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| walter and eliza hall institute ranking: Public Health Service Grants and Awards by the National Institutes of Health , 1966 |
| walter and eliza hall institute ranking: Public Health Service Publication , |
| walter and eliza hall institute ranking: Toxicogenomics in non-mammalian species Stephen Sturzenbaum, Michael Aschner, Jonathan Freedman, Some molecules or conditions are exclusively toxic to biological systems and classified as being non-essential; others are essential for life. Nevertheless, above certain threshold even the essential will become toxic. Tightly controlled homeostatic control mechanisms are thus vital drivers of well being, longevity and survival. The identification and characterization of these intricate pathways form the foundations of Toxicogenomics. The initiation, and indeed completion, of numerous non-mammalian genome-sequencing projects, has driven the exponential growth of available genetic sequences. Collating this vast amount of data into functional and mechanistically meaningful units will provide novel insights into pathogenesis, new methods of risk assessment, genetic risk-modifications in preventative medicine and new therapeutic targets for pharmaceutical and biological medicines. This Research Topic issue will explore the current knowledgebase pertaining to the multitude of genomic and toxicological tools within non-mammalian organisms. The encyclopaedic coverage will span the full taxonomic breadth ranging from simple unicellular bacteria and yeast to complex creatures such as birds and fish. The resulting collection of unique, complimentary or indeed contrasting approaches, tools and technologies (which are defined by the availability and feasibility for each organism to study genomics of xenobiotic or stress biology) will not only foster cross-phyla awareness but expand the horizon of Toxicogenomics. |
| walter and eliza hall institute ranking: Australian Science in the Making R. W. Home, Roderick Weir Home, 1990-09-28 In this 1989 volume the Australian Academy of Science celebrates and assesses two centuries of Australian science. |
| walter and eliza hall institute ranking: Medical Journal of Australia , 1926 |
| walter and eliza hall institute ranking: Regulation of Tissue Responses: The TWEAK/Fn14 Pathway and other TNF/ TNFR Superfamily Members that Activate Noncanonical NFkB Signaling Linda C. Burkly, Timothy S. Zheng, John Silke, 2016-01-21 The immune system mediates tissue responses under both physiological and pathological conditions, impacting the inflammatory, fibrogenic and regenerative components. In addition to various leukocyte subsets, it is now recognized that epithelial, endothelial and other non-hematopoietic tissue cell types actively contribute to the interplay shaping tissue responses. Further understanding the molecular pathways and mechanisms mediating these tissue responses is of great interest. In the past decade, TNF-like weak inducer of apoptosis (TWEAK) and its receptor, FGF-inducible molecule-14 (Fn14), members of the TNF/TNFR superfamily, have emerged as a prominent molecular axis regulating tissue responses. Generally leukocyte-derived, TWEAK signals through Fn14 which is highly induced in injured and diseased tissues on the surface of parenchymal, stromal and progenitor cells, thereby orchestrating a host of tissue-shaping responses, including inflammation, angiogenesis, cell proliferation or death, and the regulation of progenitor cells. Compelling preclinical results indicate that whereas transient TWEAK/Fn14 activation promotes productive tissue responses after acute injury, excessive or persistent TWEAK/Fn14 activation drives pathological tissue responses, leading to progressive damage and degeneration in target organs of injury, autoimmune and inflammatory diseases and cancer. Given that the highly inducible pattern of Fn14 expression is well conserved between mouse and man, the role of TWEAK/Fn14 in human disease is an area of intense investigation. Recent findings have also begun to shed light on how the TWEAK/Fn14 pathway fits into the immune network, interplaying with other well-established pathways, including TNFa, IL-17, IL-13 and TGFb, in regulating tissue responses. The noncanonical nuclear factor kB (NF?B) pathway plays a role in immunity and disease pathologies and appears to be activated by only a subset of TNF/ TNFR superfamily members. Of the various signaling pathways downstream of TWEAK/Fn14, particular attention has been placed on the noncanonical NF?B pathway given that given that TWEAK induces acute activation of canonical NF?B but prolonged activation of noncanonical pathway. Thus dovetailing of the TWEAK/Fn14 axis with noncanonical NF?B pathway activation may be a key mechanism underlying tissue responses. Also of great interest is a deeper understanding of where, when and how tissue responses are regulated by other TNF/ TNFR superfamily members that can signal through noncanonical NF?B. This Research Topic issue will cover: 1. TWEAK/Fn14 pathway biology, role in tissue responses, injury, and disease pathogenesis 2. Role of noncanonical NFkB signaling cascade in tissue responses 3. Translational studies of relevance of TWEAK/Fn14 and noncanonical NFkB in human disease 4. Other TNF superfamily members’ signaling through noncanonical NFkB in the regulation of tissue responses 5. Reviews and Perspectives on the above |
| walter and eliza hall institute ranking: Essential Kinases and Transcriptional Regulators and Their Roles in Autoimmunity Raffi Gugasyan, Margaret Hibbs, Marc Pellegrini, 2020-08-06 |
| walter and eliza hall institute ranking: To Win the Battle Robert C. Stevenson, 2013 In 1915 the 1st Australian Division led the way ashore at Gallipoli. In 1916 it achieved the first Australian victory on the Western Front at Pozières. It was still serving with distinction in the battles that led to the defeat of the German army in 1918. To Win the Battle explains how the division rose from obscurity to forge a reputation as one of the great fighting formations of the British Empire during the First World War, forming a central part of the Anzac legend. Drawing on primary sources as well as recent scholarship, this fresh approach suggests that the early reputation of Australia's premier division was probably higher than its performance warranted. Robert Stevenson shows that the division's later success was founded on the capacity of its commanders to administer, train and adapt to the changing conditions on the battlefield, rather than on the innate qualities of its soldiers. |
| walter and eliza hall institute ranking: Journal of the American Medical Association , 1919 |
| walter and eliza hall institute ranking: The Journal of the American Medical Association American Medical Association, 1919 Includes proceedings of the Association, papers read at the annual sessions, and list of current medical literature. |
| walter and eliza hall institute ranking: British Medical Journal , 1916 |
| walter and eliza hall institute ranking: Making Waves David Penington, 2010 Engaging and well-written, this memoir offers insight into the public and private life of David Penington, one of Australia's leading public health experts and the former vice chancellor of the University of Melbourne. A fascinating read, the narrative reveals a tireless leader who, at every stage of his working life, has never shunned public controversy in a bid to improve the lives of all Australians. From his appointment to St. Vincent’s Hospital through his assistance in the implementation of the Medicare system, this autobiography highlights Penington’s accomplishments and contributions to Australia’s national public health policy. |
| walter and eliza hall institute ranking: Nation's Health , 1924 |
| walter and eliza hall institute ranking: Nation's Health John Augustus Lapp, Charles-Edward Amory Winslow, Frank Leslie Rector, 1924 |
| walter and eliza hall institute ranking: Proceedings of the Linnean Society of New South Wales Linnean Society of New South Wales, 1928 |
| walter and eliza hall institute ranking: R & D Contracts, Grants for Training, Construction, and Medical Libraries , 1989 |
| walter and eliza hall institute ranking: Research and Development Contracts , |
| walter and eliza hall institute ranking: The British Australasian , 1919 |
| walter and eliza hall institute ranking: Breast Cancer: New Insights for the Healthcare Professional: 2011 Edition , 2012-01-09 Breast Cancer: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Breast Cancer. The editors have built Breast Cancer: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Breast Cancer in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Breast Cancer: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
| walter and eliza hall institute ranking: The Lancet , 1907 |
| walter and eliza hall institute ranking: Selected Works of Terry Speed Sandrine Dudoit, 2012-04-11 The purpose of this volume is to provide an overview of Terry Speed’s contributions to statistics and beyond. Each of the fifteen chapters concerns a particular area of research and consists of a commentary by a subject-matter expert and selection of representative papers. The chapters, organized more or less chronologically in terms of Terry’s career, encompass a wide variety of mathematical and statistical domains, along with their application to biology and medicine. Accordingly, earlier chapters tend to be more theoretical, covering some algebra and probability theory, while later chapters concern more recent work in genetics and genomics. The chapters also span continents and generations, as they present research done over four decades, while crisscrossing the globe. The commentaries provide insight into Terry’s contributions to a particular area of research, by summarizing his work and describing its historical and scientific context, motivation, and impact. In addition to shedding light on Terry’s scientific achievements, the commentaries reveal endearing aspects of his personality, such as his intellectual curiosity, energy, humor, and generosity. |
| walter and eliza hall institute ranking: The Medical Journal of Australia , 1919 |
| walter and eliza hall institute ranking: Incentivising Angels Stephen Barkoczy, Tamara Wilkinson, 2019-04-24 This book examines tax incentives for investors in start-up companies through a critical analysis of Australia’s early-stage investors (ESI) program, and a comparison of that program with the United Kingdom’s Seed Enterprise Investment Scheme (SEIS) upon which it is loosely modelled. It discusses the importance of innovation and the special role that venture capital plays in supporting start-ups, and explains the policy rationale for introducing the ESI program as well as dissecting its technical requirements in detail. Special attention is devoted to the program’s ‘early stage’ and ‘innovation’ requirements, which are crucial for determining whether a start-up qualifies for the tax incentives. The book is the first in-depth scholarly legal analysis of the ESI program and the first occasion it has been compared and contrasted with a foreign program. The comparative discussion of the ESI program with the SEIS program enables the authors to make suggestions for reforms to the ESI program so that it can better achieve its policy objectives. The fact that the book includes reform suggestions makes it particularly interesting for policy makers. It is also of broad relevance to legal and finance scholars and students as well as entrepreneurs, angels, venture capitalists and their advisors. |
| walter and eliza hall institute ranking: Indonesia's Technological Challenge Hal Hill, Kian Wie Thee, 1998 This volume provides a lively review of recent economic and political developments in Indonesia and addresses the issue of the country's Technological Challenge from a variety of perspectives. These include the policy foundations, the analytical issues, case studies, international co-operation and transfers, as well as particular challenges at the sectoral level and among both large and small enterprises. This is the first volume in English to examine these important questions facing the world's fourth largest country. |
| walter and eliza hall institute ranking: BRW. , 2005 |
| walter and eliza hall institute ranking: Higher Education in Regional and City Development: State of Victoria, Australia 2010 OECD, 2010-12-08 This publication explores a range of helpful policy measures and institutional reforms to mobilise higher education for the development of the State of Victoria. |
| walter and eliza hall institute ranking: The Bulletin of the American College of Physicians , 1964 |
| walter and eliza hall institute ranking: Public Health Service grants and awards. 1966 pt. 3-5 |publ 1967 , 1959* |
| walter and eliza hall institute ranking: Nature, Nurture and Chance Frank Fenner, 2006-07-01 Microbiologists; Virologists; Educators; Geographers; Biography; Australia. |
| walter and eliza hall institute ranking: Building, Lighting and Engineering , 1926 |
| walter and eliza hall institute ranking: The Shop Richard Joseph Wheeler Selleck, 2003 Telling as much a social, educational, and cultural story as institutional history, this detailed account chronicles the ideological patterns, internal and countrywide conflicts, and student experiences at the University of Melbourne from 1850 to 1939. The daily life of staff, professors, and students are recounted during times of turmoil and peace in Australia, including the depression of the 1890s and World War I. The account offers a window into the pedagogical conflicts and research achievements of one of Australia's oldest continuing educational institutions. |
| walter and eliza hall institute ranking: IMS Bulletin , 2007 |
| walter and eliza hall institute ranking: The Bulletin , 1992-11 |
| walter and eliza hall institute ranking: The Australian Journal of Science , 1949 |
| walter and eliza hall institute ranking: Votes and Proceedings of the Legislative Assembly Victoria. Parliament. Legislative Assembly, 1928 |
| walter and eliza hall institute ranking: Emerging Infectious Diseases , 2013 |
| walter and eliza hall institute ranking: Abstracts in Biocommerce , 1989 |
| walter and eliza hall institute ranking: The Price of Health James A. Gillespie, James Alexander Gillespie, 2002-06-06 This 1991 book is a history of political conflict over health policy in Australia, providing background to an ongoing debate. |
| walter and eliza hall institute ranking: The Roll of the Royal College of Physicians of London Royal College of Physicians of London, William Munk, 1989 |
| walter and eliza hall institute ranking: The Rose and Mackay Textbook of Autoimmune Diseases M. Eric Gershwin, George C. Tsokos, Betty Diamond, 2024-08-05 The Rose-Mackay Textbook of Autoimmune Diseases, Seventh Edition is a comprehensive reference that emphasizes the 3 P's of 21st Century medicine: precision, prediction, and prevention. Topics cover the modern systems approach to biology that involves large amounts of personalized, ongoing physiologic data (omics) coupled with advanced methods of analysis, new tests of genetic engineering, such as CRISPR, auto inflammatory diseases, autoimmune responses to tumor immunotherapy, and information on normal immune response and disorders. Each of the major autoimmune disorders is discussed by researchers and clinical investigators experienced in dealing with patients.This new edition continues its success with 75% of the content revised, updated, or completely new. This edition is a valuable resource to clinicians involved in the diagnosis and treatment of autoimmune disease, as well as to scientists who want to follow developments in the field. - Provides new research on autoimmune diseases, their diagnosis, prevention, and therapy - Covers a complete range of all common, rare and new autoimmune diseases, including cancer and COVID - Extensively revised with 75% new material based on autoimmunity, developments in the different diagnosis and therapies for these autoimmune diseases, and a completely updated description of the different diseases - Supplemented with a website that hosts a Podcast per chapter |
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