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| top drug interactions: Handbook of Drug Interactions Ashraf Mozayani, Lionel Raymon, 2003-10-15 A concise compilation of the known interactions of the most commonly prescribed drugs, as well as their interaction with nonprescription compounds. The agents covered include CNS drugs, cardiovascular drugs, antibiotics, and NSAIDs. For each class of drugs the authors review the pharmacology, pharmacodynamics, pharmacokinetics, chemistry, metabolism, epidemiological occurrences, adverse reactions, and significant interactions. Environmental and social pharmacological issues are also addressed in chapters on food and alcohol drug interactions, nicotine and tobacco, and anabolic doping agents. Comprehensive and easy-to-use, Handbook of Drug Interactions: A Clinical and Forensic Guide provides physicians with all the information needed to avoid prescribing drugs with undesirable interactions, and toxicologists with all the data necessary to interpret possible interactions between drugs found simultaneously in patient samples. |
| top drug interactions: Drug-Drug Interactions A. David Rodrigues, 2019-01-03 Authored by renowned leaders in the field, this comprehensive volume covers all aspects of drug-drug interactions, including preclinical, clinical, toxicological, and regulatory perspectives.Thoroughly updated, this second edition reflects the significant advances and includes extensive new material on:key interplay between transporters and enzymes |
| top drug interactions: Herb, Nutrient, and Drug Interactions Mitchell Bebel Stargrove, Jonathan Treasure, Dwight L. McKee, 2007-12-06 Presenting detailed, evidence-based coverage of the most commonly encountered therapeutic agents in modern clinical practice, this resource is designed to help you safely and effectively integrate herbal, nutrient, and drug therapy for your patients or clients. Combining pharmaceuticals with herbs or supplements may complement or interfere with a drug's therapeutic action or may increase adverse effects. Additionally, drug-induced depletion of nutrients can occur. Comprehensive clinical data, quick-reference features, and the insight and expertise of trusted authorities help you gain a confident understanding of how herbal remedies and nutritional supplements interact with pharmaceuticals and develop safe, individualized treatment strategies for your patients. More than 60 comprehensive monographs of herb-drug and nutrient-drug interactions cover the most commonly used herbs and nutrients in health-related practice and help you coordinate safe, reliable therapy. Each herb and nutrient monograph features summary tables and concise, practical suggestions that provide quick and easy reference and complement the systematic review and in-depth analysis. References included on the bound-in CD provide high-quality, evidence-based support. Unique icons throughout the text differentiate interactions, evidence, and clinical significance. Up-to-date information keeps you current with the latest developments in pharmacology, nutrition, phytotherapy, biochemistry, genomics, oncology, hematology, naturopathic medicine, Chinese medicine, and other fields. A diverse team of authoritative experts lends valuable, trans-disciplinary insight. |
| top drug interactions: A Case Approach to Perioperative Drug-Drug Interactions Catherine Marcucci, Michael P. Hutchens, Erica D. Wittwer, Toby N. Weingarten, Juraj Sprung, Wayne T. Nicholson, Kirk Lalwani, David G. Metro, Randal O. Dull, Christopher E. Swide, F. Jacob Seagull, Jeffrey R. Kirsch, Neil B. Sandson, 2015-09-15 The occurrence of deleterious or even fatal drug-drug interactions (DDIs) in the perioperative period is no longer a theoretical concern but a harrowing reality. A Case Approach to Perioperative Drug-Drug Interactions addresses the complex realm of pharmacokinetic drug interactions in an easy-to-read volume that functions as both a comprehensive clinical reference and a casebook. The book presents a summary of the core concepts of drug interactions; an organized, annotated presentation of the drug interactions most relevant to the perioperative clinician; and approximately 200 case scenarios that highlight specific drug interactions. This book fills a real void in the clinical literature and is invaluable to anesthesiologists and surgeons, as well as trainees in both specialties; intensive care staff, including physicians, physician’s assistants, and nurses; and nurse practitioners who staff preoperative evaluation clinics. |
| top drug interactions: Stockley's Drug Interactions 9 Ivan H. Stockley, 2010 |
| top drug interactions: Guidelines for the Psychosocially Assisted Pharmacological Treatment of Opioid Dependence World Health Organization. Department of Mental Health and Substance Abuse, World Health Organization, 2009 These guidelines were produced by the World Health Organization (WHO), Department of Mental Health and Substance Abuse, in collaboration with the United Nations Office on Drugs and Crime (UNODC) a Guidelines Development Group of technical experts, and in consultation with the International Narcotics Control Board (INCB) secretariat and other WHO departments. WHO also wishes to acknowledge the financial contribution of UNODC and the Joint United Nations Programme on HIV/AIDS (UNAIDS) to this project. - p. iv |
| top drug interactions: Mechanisms of Drug Interactions Patrick F. D'Arcy, James C. McElnay, Peter G. Welling, 2012-12-06 Over the years a number of excellent books have classified and detailed drug drug interactions into their respective categories, e.g. interactions at plasma protein binding sites; those altering intestinal absorption or bioavailability; those involving hepatic metabolising enzymes; those involving competition or antagonism for receptor sites, and drug interactions modifying excretory mechanisms. Such books have presented extensive tables of interactions and their management. Although of considerable value to clinicians, such publica tions have not, however, been so expressive about the individual mechanisms that underlie these interactions. It is within this sphere of mechanisms that this present volume specialises. It deals with mechanisms of in vitro and in vivo, drug-drug, drug food and drug-herbals interactions and those that cause drugs to interfere with diagnostic laboratory tests. We believe that an explanation of the mechanisms of such interactions will enable practitioners to understand more fully the nature of the interactions and thus enable them to manage better their clinical outcome. If mechanisms of interactions are better understood, then it may be pos sible for the researcher to develop meaningful animal/biochemical/tissue cul ture or physicochemical models to which new molecules could be exposed during their development stages. The present position, which largely relies on patients experiencing adverse interactions before they can be established or documented, can hardly be regarded as satisfactory. This present volume is classified into two major parts; firstly, pharmacoki netic drug interactions and, secondly, pharmacodynamic drug interactions. |
| top drug interactions: Drug Interaction Facts , 2008 |
| top drug interactions: Encyclopedia of Molecular Pharmacology Stefan Offermanns, W. Rosenthal, 2008-08-14 An essential text, this is a fully updated second edition of a classic, now in two volumes. It provides rapid access to information on molecular pharmacology for research scientists, clinicians and advanced students. With the A-Z format of over 2,000 entries, around 350 authors provide a complete reference to the area of molecular pharmacology. The book combines the knowledge of classic pharmacology with the more recent approach of the precise analysis of the molecular mechanisms by which drugs exert their effects. Short keyword entries define common acronyms, terms and phrases. In addition, detailed essays provide in-depth information on drugs, cellular processes, molecular targets, techniques, molecular mechanisms, and general principles. |
| top drug interactions: Drug Interactions in Infectious Diseases Stephen C. Piscitelli, Keith A. Rodvold, Manjunath P. Pai, 2011-09-08 The revised and up-to-date third edition of Drug Interactions in Infectious Diseases delivers a text that will enhance your clinical knowledge of the complex mechanisms, risks, and consequences of drug interactions associated with antimicrobials, infection, and inflammation. The third edition features five new chapters that cover material not addressed in previous editions. These new chapters describe interactions with a number of drug classes such as non-HIV antiviral, antimalarial, antiparasitic, antihelmintic, macrolide, azalide and ketolide agents. A novel chapter on probe cocktail studies has been included to highlight an important research tool for drug development. These chapters address material that cannot be retrieved easily in the medical literature. The highly acclaimed food-drug interactions as well as the study design and analysis chapters remain definitive references. The newly written drug-cytokine interaction highlights the need for our improved understanding of the complex interrelationship of acute infection, inflammation, and the risk of drug interactions. Informative tables on specific drug-drug interactions are provided throughout the chapters as a quick clinical resource. The Third Edition of Drug Interactions in Infectious Diseases is a distillation of relevant drug interactions associated with antimicrobials, infection, and inflammation. This concise review of the mechanisms and strategies to manage drug interactions should be valuable to all health care practitioners. Features • Definitive reference source of up-to-date information on antimicrobial drug interactions • Informative tables on the degree of interaction for specific antimicrobial agents • In-depth discussion of mechanisms and potential mechanistic pathways of interaction • New chapters on non-HIV antiviral, antimalarial, antiparasitic, and macrolide, azalide and ketolide agents • New chapter on probe-cocktail studies as a research tool to study drug-drug interactions • Inclusion of new antimicrobial agents and their associated drug interactions • First rate chapters on study design and analysis, and drug-food interactions • A fresh perspective on drug-cytokine interactions • Authoritative chapter on regulatory considerations of drug interactions during drug development |
| top drug interactions: The Top 100 Drugs Andrew Hitchings, Dagan Lonsdale, Daniel Burrage, Emma Baker, 2022-11 Now in its third edition, this small and accessible guide contains essential information for the safe prescribing of the most commonly used drugs in the NHS. The Top 100 Drugs combines the best elements of a students' textbook with those of a prescribers' manual. It gives equal weight to essential information on the science of pharmacology as well as the real-world practicalities of prescribing, all in an accessible and clear format. Written by leaders in the field of clinical pharmacology, this popular book has been fully revised and updated to include the drugs used today, including monoclonal antibodies and antiviral drugs for COVID-19. With common indications, mechanism of action, adverse effects, important interactions and a clinical tip for each drug as well as questions to test knowledge, this book is key to helping students understand everything they need to know about the drugs they are likely to use in practice. Compact and easy to follow - can be carried around on the wards Logically ordered - offers multiple ways to find the drug you are looking for A Clinical Tip for each drug, drawn from the authors' experience 100 self-assessment questions to encourage integration and revision of knowledge and understanding Fully updated to include the most commonly prescribed drugs today, based on original research led by the authors of over 1 billion community prescriptions and approximately 1 million hospital prescriptions All drug monographs extensively reviewed and updated Dedicated section emergency drugs Updated self-assessment material, now including calculation and prescription-writing questions, in addition to single-best-answer questions |
| top drug interactions: The ESC Textbook of Cardiovascular Medicine A. John Camm, 2019 |
| top drug interactions: Lexi-Comp's Drug Interactions Handbook Kenneth A. Bachmann, 2004 |
| top drug interactions: Top 300 Drugs Pocket Reference Guide (2024 Edition) Coventry House Publishing, 2024-07-23 The Top 300 Drugs Pocket Reference Guide serves as a portable reference to learn the essential information for the most commonly prescribed drugs. This on-the-go resource details the brand name, pharmacologic class, mechanism of action, dosage form, common use, and other clinical details for each drug. Whether you’re a pharmacy student or healthcare professional, this guide will serve as an effective resource to learn the basic characteristics of the most popular drugs. Drug details include: • Brand Names • Pharmacologic Classes • Mechanisms of Action • Common Uses • Dosage Forms • Dosing Information • Administration Methods • Monitoring Guidelines • Contraindications • Drug Interactions • Adverse Effects • Black Box Warnings |
| top drug interactions: Herb Contraindications and Drug Interactions Francis J. Brinker, 1998 |
| top drug interactions: Stockley's Drug Interactions Pocket Companion 2016 Claire L. Preston, 2016 Stockley's Drug Interactions Pocket Companion 2016 is a portable, easy-to-use, A-Z guide to common drug interactions. This new edition is based on the latest updates of Stockley's Drug Interactions and offers evidence-based guidance on the management of common drug-drug, drug-herb, and drug-food interactions. Key features include: - New and updated interactions advice, including revalidation of the Antidiabetics monographs - Over 2300 monographs - A comprehensive back-of-book index - Severity rating symbols to indicate the clinical significance of each interaction. Presented in the familiar style of the Stockley family of products, the quick-reference format makes this an essential clinical reference for physicians, pharmacists, nurses, and other healthcare professionals. |
| top drug interactions: Antibiotics Simplified Jason C. Gallagher, Conan MacDougall, 2008-05-22 Antibiotics Simplified is a succinct guide designed to bridge knowledge gained in basic sciences courses with clinical practice in infectious diseases. Introductory chapters explain the rationale behind the treatment of infectious diseases, describe a system for selecting antimicrobial agents and briefly review basic microbiology. Later chapters present relevant characteristics of drug classes, emphasizing clinical pearls for individual agents, and also include content on antifungals. The concise nature of the text allows for emphasis on key points, allowing readers to extract the most important characteristics of anti-infective drugs from the larger mass of material that they learn from detailed pharmacology textbooks. This is an ideal handbook for students as well as practicing clinicians and pharmacists. |
| top drug interactions: Depression in Adults with a Chronic Physical Health Problem National Collaborating Centre for Mental Health (Great Britain), 2010 This clinical guideline was commissioned by NICE and developed by the National Collaborating Centre for Mental Health. It sets out clear, evidence - and consensus-based recommendations for healthcare staff on how to treat and manage depression in adults with a chronic physical health problem. A fifth of people with a chronic physical health problem (such as cancer, diabetes, heart disease and stroke) have depression - a rate that is two to three times higher than in those who are in good physical health. A combination of depression and a chronic physical health problem can significantly worsen the negative outcomes for people with both conditions. The NICE Guideline is an invaluable resource enabling healthcare professionals to address these problems and recognize, assess and offer effective treatments for depression in people with a chronic physical health problem. The guideline reviews the evidence for the identification of depression in people with a chronic physical health problem and the associated service-level interventions (such as stepped care and collaborative care) and psychosocial, psychological and pharmacological interventions. It places special emphasis on advising health professionals about interactions between antidepressants and any prescribed medication for the physical health problem. As in the updated edition of The NICE Guideline on depression, this guideline also covers subthreshold depressive symptoms. It has a useful introduction to depression in adults with a chronic physical health problem and a chapter on service user, carer and staff experience of care. An accompanying CD contains further information about the evidence, including: characteristics of included studies; profile tables that summarize both the quality of the evidence and the results of the evidence synthesis; all meta-analytical data presented as forest plots; and, detailed information about how to use and interpret forest. |
| top drug interactions: Drug-Drug Interactions Dong Hyun Kim, Sangkyu Lee, 2021-09-17 Drug-drug interactions (DDIs) cause a drug to affect other drugs, leading to reduced drug efficacy or increased toxicity of the affected drug. Some well-known interactions are known to be the cause of adverse drug reactions (ADRs) that are life threatening to the patient. Traditionally, DDI have been evaluated around the selective action of drugs on specific CYP enzymes. The interaction of drugs with CYP remains very important in drug interactions but, recently, other important mechanisms have also been studied as contributing to drug interaction including transport- or UDP-glucuronyltransferase as a Phase II reaction-mediated DDI. In addition, novel mechanisms of regulating DDIs can also be suggested. In the case of the substance targeted for interaction, not only the DDIs but also the herb-drug or food-drug interactions have been reported to be clinically relevant in terms of adverse side effects. Reporting examples of drug interactions on a marketed drug or studies on new mechanisms will be very helpful for preventing the side effects of the patient taking these drugs. This Special Issue aims to highlight current progress in understanding both the clinical and nonclinical interactions of commercial drugs and the elucidation of the mechanisms of drug interactions. |
| top drug interactions: Nutrient-Drug Interactions Kelly Anne Meckling, 2006-06-23 Current research has given us a more complete understanding of how the chemicals in foods and herbs interact with natural and synthetic drugs. In some cases a single food or supplement can profoundly increase or decrease the toxicity and/or efficacy of a single drug. Although it is standard practice to examine the effects of food consumption on the |
| top drug interactions: The Top 100 Drug Interactions Philip D. Hansten, John R. Horn, 2004-02 |
| top drug interactions: Stockley's Herbal Medicines Interactions Elizabeth M. Williamson, 2009 This book contains data on over 150 of the most commonly used herbal medicines, dietary supplements and nutraceuticals. |
| top drug interactions: Handbook of Drug'nutrient Interactions Joseph I. Boullata, Vincent T. Armenti, 2014-01-15 |
| top drug interactions: Deep Learning for Coders with fastai and PyTorch Jeremy Howard, Sylvain Gugger, 2020-06-29 Deep learning is often viewed as the exclusive domain of math PhDs and big tech companies. But as this hands-on guide demonstrates, programmers comfortable with Python can achieve impressive results in deep learning with little math background, small amounts of data, and minimal code. How? With fastai, the first library to provide a consistent interface to the most frequently used deep learning applications. Authors Jeremy Howard and Sylvain Gugger, the creators of fastai, show you how to train a model on a wide range of tasks using fastai and PyTorch. You’ll also dive progressively further into deep learning theory to gain a complete understanding of the algorithms behind the scenes. Train models in computer vision, natural language processing, tabular data, and collaborative filtering Learn the latest deep learning techniques that matter most in practice Improve accuracy, speed, and reliability by understanding how deep learning models work Discover how to turn your models into web applications Implement deep learning algorithms from scratch Consider the ethical implications of your work Gain insight from the foreword by PyTorch cofounder, Soumith Chintala |
| top drug interactions: Transporters and Drug-Metabolizing Enzymes in Drug Toxicity Albert P. Li, 2021-07-27 TRANSPORTERS AND DRUG-METABOLIZING ENZYMES IN DRUG TOXICITY Explore up-to-date coverage on the interaction between drug metabolism enzymes, transporters, and drug toxicity with this leading resources Transporters and Drug-Metabolizing Enzymes in Drug Toxicity delivers a comprehensive and updated review of the relationship between drug metabolism, transporters, and toxicity, providing insights into a major challenge in drug development – accurate assessment of human drug toxicity. Combining two disciplines frequently considered independently of one another, the book combines drug metabolism and toxicology with a focus on the role of biotransformation on drug toxicity and as a major factor for species and individual differences. Mechanism and species differences in drug metabolizing enzymes and transporters are discussed, as are the methods used to investigate the role of drug metabolizing enzymes and transporters in drug toxicity. Finally, the distinguished authors describe promising new experimental approaches to accurately assessing human drug toxicity via the consideration of human-specific drug metabolism in toxicity assays. In addition to topics as diverse as extended clearance models, experimental approaches for the estimation of DILI potential of drug candidates and roles of transporters in renal drug toxicity, readers will also enjoy the inclusion of such subjects as: A thorough overview of and introduction to drug metabolism and transporters and drug toxicity An exploration of drug metabolism enzymes and transporter activities as risk factors of marketed drugs associated with drug-induced fatalities A discussion of human-based in vitro experimental models for the evaluation of metabolism-dependent drug toxicity A treatment of mechanism-based experimental models for the evaluation of BSEP inhibition and DILI An examination of transporters and cochlea toxicity Perfect for scientists, students, and practitioners with interests in metabolism, toxicology, and drug development in the pharmaceutical industry, Transporters and Drug-Metabolizing Enzymes in Drug Toxicity will also earn a place in the libraries of medicinal chemists, pharmacologists, biochemists, toxicologists, and regulators in the pharmaceutical and health industries. |
| top drug interactions: The Top 100 Drug Interactions Philip D. Hansten, John R. Horn, 2002 |
| top drug interactions: Worst Pills, Best Pills Sid M. Wolfe, 2009-04-14 More than 100,000 people a year die in American hospitals from adverse reactions to medication, making drug reactions one of the leading causes of death in this country, researchers are reporting today.... -- Journal of the American Medical Association study, as quoted in The New York Times It is no longer a secret that adverse drug reactions can be dangerous or even fatal, or that doctors often prescribe two relatively safe drugs -- which may cause a life-threatening interaction if taken together. THIS IS THE BOOK THAT TELLS YOU WHAT OTHER PILL BOOKS WON'T ABOUT YOUR MEDICATION! Top-selling drugs that are among the 160 Do Not Use Drugs discussed inside: Ultram Darvoset-N Lopid Desogen & OrthoCept Elavil Ativan Restoril Flexeril Valium Bentyl Entex LA Glucophage Macrobid Patients fill more than 80 million prescriptions a year for these drugs! Consumer advocate Sidney M. Wolfe, M.D., director of Public Citizen's Health Research Group, has thoroughly revised and updated this accessible, indispensable bestseller that alerts you to the potential risks of hundreds of medications available today. Worst Pills, Best Pills gives you the information you need to become actively involved in caring for yourself -- by asking your doctor smart questions about the drugs prescribed for you. Arranged by disease/condition, it offers chapters on adverse drug reactions, alphabetical indexes listing pills by their brand and generic names, new information about commonly used drugs, guidelines for helping you to say no if your doctor prescribes a drug you should not take, and safer alternative choices. Worst Pills, Best Pills also includes startling information about certain drugs that can actually cause depression, hallucinations or psychoses, sexual dysfunction, dementia, auto accidents, insomnia, parkinsonism, and more. Caution: Call your doctor before stopping the use of any drug. |
| top drug interactions: Food Medication Interactions Zaneta M. Pronsky, Keith Ayoob, 2015 |
| top drug interactions: Martindale Sean C. Sweetman, 2006-01-01 This is thirty-fifth edition of Martindale, which provides reliable, and evaluated information on drugs and medicines used throughout the world. It contains encyclopaedic facts about drugs and medicines, with: 5,500 drug monographs; 128,000 preparations; 40,700 reference citations; 10,900 manufacturers. There are synopses of disease treatments which enables identification of medicines, the local equivalent and the manufacturer. It also Includes herbals, diagnostic agents, radiopharmaceuticals, pharmaceutical excipients, toxins, and poisons as well as drugs and medicines. Based on published information and extensively referenced |
| top drug interactions: Meded101 Guide to Drug Food Interactions Eric Christianson, 2020-07-16 This is the perfect book for clinical rounds and internships! Food can significantly alter the concentrations of some medications. Alternatively, medications can contribute to nutritional deficiencies and other dietary complications. In this reference book, we lay out over 500 of the most commonly used medications and how they impact diet or how diet can alter the effects of drugs. This guide is designed to highlight important food and drug interactions with the most commonly used medications in clinical practice. In addition to highlighting potential food medication interactions, we have also laid out common adverse effects, indications, clinical pearls, mechanisms of action, and monitoring parameters that are critical for each medication. This is meant to be a quick reference for healthcare professionals and students who work in healthcare as dietitians, pharmacists, nurses, nurse practitioners, physicians, physician assistants, and others. |
| top drug interactions: Pharmacokinetic and Pharmacodynamic Drug Interactions Associated with Antiretroviral Drugs Tony K. L. Kiang, Kyle John Wilby, Mary H. H. Ensom, 2018-07-07 Clinically-focussed, with easily accessible tables and chapter summaries suitable for clinicians and researchers, this comprehensive book provides a systematic, critical evaluation of the current literature. An updated clinical decision-making algorithm specifically tailored to the antiretroviral drugs is also provided. The identified interactions are interpreted in the context of known mechanisms derived from clinical, preclinical, and in vitro data. The clinical relevance of the interactions is systematically evaluated and gaps in literature discussed in the context of potential future experiments. In addition to the comprehensive summary of pharmacokinetic and pharmacodynamic drug interactions associated with WHO-recommended antiretroviral drugs on the market today (i.e. nucleotide reverse-transcriptase inhibitors, non-nucleoside reverse-transcriptase inhibitors, integrase inhibitors, and protease inhibitors), this book also provides detailed section summaries on the epidemiology of HIV infection, diagnosis and pharmacotherapy, basic pharmacology of the individual antiretrovirals, pertinent pre-clinical and in vitro molecular pharmacology, and in vitro drug interaction data available in the literature today. |
| top drug interactions: Drug Interactions National Library of Medicine (U.S.). Toxicology Information Program, 1972 |
| top drug interactions: The Pill Book Harold M. Silverman, 2017-07-26 The Pill BookBy Harold M. Silverman |
| top drug interactions: Drug Interactions in Anesthesia Norman Ty Smith, 1986 |
| top drug interactions: Drug Interactions; an Annotated Bibliography with Selected Excerpts: 1970-1971 National Library of Medicine (U.S.). Toxicology Information Program, 1972 |
| top drug interactions: The Top 100 Drug Interactions, 2013 Philip D. Hansten, John R. Horn, 2013-01-01 |
| top drug interactions: A Manual of Adverse Drug Interactions J.P. Griffin, P.F. D'Arcy, 1997-11-17 For twenty years this book, now in its 5th edition, has provided information on adverse drug interactions that is unrivalled in coverage and scholarship.Adverse drug reactions, many of them ascribable to interactions with other drugs or with chemical substances in food or the environment, are thought to cause or complicate one in twenty of hospital admissions.The book is conveniently divided into two parts: Part 1 comments on drug interactions and their mechanisms, on a pharmacokinetic and pharmacodynamic level, while Part 2 consists of drug interaction tables, divided and subdivided into categories of disorders, and the drugs used in the treatment of these disorders.If safety in drugs is to improve, education of prescribers is vitally important. This book, with its up-to-date and coordinated approach, serves that purpose well. The real threat, as the authors remind us, is the ignorance of practitioners, not the drug itself. The volume is therefore an essential addition to the shelves of those responsible for the prescription of drugs, in order to prevent a potential backlash when used in combination with other drugs or chemical substances. |
| top drug interactions: Drug Interactions; an Annotated Bibliography with Selected Excerpts National Library of Medicine (U.S.). Toxicology Information Program, 1972 |
| top drug interactions: Top Screwups Doctors Make and How to Avoid Them Joe Graedon, Teresa Graedon, 2012-09-11 A primary care doctor is skeptical of his patient’s concerns. A hospital nurse or intern is unaware of a drug’s potential side effects. A physician makes the most “common” diagnosis while overlooking the signs of a rarer and more serious illness, and the patient doesn’t see the necessary specialist until it’s too late. A pharmacist dispenses the wrong drug and a patient dies as a result. Sadly, these kinds of mistakes happen all the time. Each year, 6.1 million Americans are harmed by diagnostic mistakes, drug disasters, and medical treatments. A decade ago, the Institute of Medicine estimated that up to 98,000 people died in hospitals each year from preventable medical errors. And new research from the University of Utah, HealthGrades of Denver, and elsewhere suggests the toll is much higher. Patient advocates and bestselling authors Joe and Teresa Graedon came face-to-face with the tragic consequences of doctors’ screwups when Joe’s mother died in Duke Hospital—one of the best in the world—due to a disastrous series of entirely preventable errors. In Top Screwups Doctors Make and How to Avoid Them, the Graedons expose the most common medical mistakes, from doctor’s offices and hospitals to the pharmacy counters and nursing homes. Patients across the country shared their riveting horror stories, and doctors recounted the disastrous—and sometimes deadly—consequences of their colleagues’ oversights and errors. While many patients feel vulnerable and dependent on their health care providers, this book is a startling wake-up call to how wrong doctors can be. The good news is that we can protect ourselves, and our loved ones, by being educated and vigilant medical consumers. The Graedons give patients the specific, practical steps they need to take to ensure their safety: the questions to ask a specialist before getting a final diagnosis, tips for promoting good communication with your doctor, presurgery checklists, how to avoid deadly drug interactions, and much more. Whether you’re sick or healthy, young or old, a parent of a young child, or caring for an elderly loved one, Top Screwups Doctors Make and How to Avoid Them is an eye-opening look at the medical mistakes that can truly affect any of us—and an empowering guide that explains what we can do about it. |
| top drug interactions: Drug Interactions in Infectious Diseases: Mechanisms and Models of Drug Interactions Manjunath P. Pai, Jennifer J. Kiser, Paul O. Gubbins, Keith A. Rodvold, 2018-03-05 The 4th edition of Drug Interactions in Infectious Diseases is being split into two separate volumes – “Mechanisms and Models of Drug Interactions” and “Antimicrobial Drug Interactions”. This volume, “Mechanisms and Models of Drug Interactions,” delivers a text that enhances clinical knowledge of the complex mechanisms, risks, and consequences of drug interactions associated with antimicrobials, infection, and inflammation. The book provides a comprehensive review of basic clinical pharmacology with a focus on metabolism and transporter-mediated drug interactions. The chapters address materials that cannot be retrieved easily in the medical literature, including materials focused on the complex interrelationship of acute infection, inflammation, and the risk of drug interactions in the Drug-Cytokine chapter. The Food-Drug and Herb-Drug interactions chapters remain definitive resources. A new chapter on in vitro modeling of drug interactions is included along with updates on design and data analysis of clinical drug interaction studies. Authoritative discussion of models for regulatory decision-making on drug-drug interactions provides the necessary framework to aid antimicrobial drug development. This concise review of the mechanisms and models of drug interactions provides important insights to health care practitioners as well as scientists in drug development. |
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