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| the cell cycle and cancer virtual lab: The Cell Cycle and Cancer Renato Baserga, 1971 |
| the cell cycle and cancer virtual lab: Labster Virtual Lab Experiments: Basic Biology Sarah Stauffer, Aaron Gardner, Dewi Ayu Kencana Ungu, Ainara López-Córdoba, Matthias Heim, 2018-11-29 This textbook helps you to prepare for both your next exams and practical courses by combining theory with virtual lab simulations. With the “Labster Virtual Lab Experiments” book series you have the unique opportunity to apply your newly acquired knowledge in an interactive learning game that simulates common laboratory experiments. Try out different techniques and work with machines that you otherwise wouldn’t have access to. In this volume on “Basic Biology” you will learn how to work in a biological laboratory and the fundamental theoretical concepts of the following topics: Lab Safety Mitosis Meiosis Cellular Respiration Protein Synthesis In each chapter, you will be introduced to the basic knowledge as well as one virtual lab simulation with a true-to-life challenge. Following a theory section, you will be able to play the corresponding simulation. Each simulation includes quiz questions to reinforce your understanding of the covered topics. 3D animations will show you molecular processes not otherwise visible to the human eye. If you have purchased a printed copy of this book, you get free access to five simulations for the duration of six months. If you’re using the e-book version, you can sign up and buy access to the simulations at www.labster.com/springer. If you like this book, try out other topics in this series, including “Basic Genetcis”, “Basic Biochemistry”, and “Genetics of Human Diseases”. Please note that the simulations included in the book are not virtual reality (VR) but 2D virtual experiments. |
| the cell cycle and cancer virtual lab: The Eukaryotic Cell Cycle J. A. Bryant, Dennis Francis, 2008 Written by respected researchers, this is an excellent account of the eukaryotic cell cycle that is suitable for graduate and postdoctoral researchers. It discusses important experiments, organisms of interest and research findings connected to the different stages of the cycle and the components involved. |
| the cell cycle and cancer virtual lab: Labster Virtual Lab Experiments: Genetics of Human Diseases Aaron Gardner, Sarah Stauffer, Lindsay Petley-Ragan, Philip Wismer, Dewi Ayu Kencana Ungu, 2019-04-01 This textbook helps you to prepare for your next exams and practical courses by combining theory with virtual lab simulations. The “Labster Virtual Lab Experiments” series gives you a unique opportunity to apply your newly acquired knowledge in a learning game that simulates exciting laboratory experiments. Try out different techniques and work with machines that you otherwise wouldn’t have access to. In this book, you’ll learn the fundamental concepts of the genetics of human diseases focusing on: Monogenic Disorders - Cytogenetics - Medical Genetics - Viral Gene Therapy In each chapter, you’ll be introduced to one virtual lab simulation and a true-to-life challenge. Following a theory section, you’ll be able to play the relevant simulation that includes quiz questions to reinforce your understanding of the covered topics. 3D animations will show you molecular processes not otherwise visible to the human eye. If you have purchased a printed copy of this book, you get free access to five simulations for the duration of six months. If you’re using the e-book version, you can sign up and buy access to the simulations at www.labster.com/springer. If you like this book, try out other topics in this series, including “Basic Biology”, “Basic Genetics”, and “Basic Biochemistry”. Please note that the simulations included in the book are not virtual reality (VR) but 2D virtual experiments. |
| the cell cycle and cancer virtual lab: K-12 STEM Education: Breakthroughs in Research and Practice Management Association, Information Resources, 2017-10-31 Education is vital to the progression and sustainability of society. By developing effective learning programs, this creates numerous impacts and benefits for future generations to come. K-12 STEM Education: Breakthroughs in Research and Practice is a pivotal source of academic material on the latest trends, techniques, technological tools, and scholarly perspectives on STEM education in K-12 learning environments. Including a range of pertinent topics such as instructional design, online learning, and educational technologies, this book is an ideal reference source for teachers, teacher educators, professionals, students, researchers, and practitioners interested in the latest developments in K-12 STEM education. |
| the cell cycle and cancer virtual lab: Revolutionizing K-12 Blended Learning through the i²Flex Classroom Model Avgerinou, Maria D., Gialamas, Stefanos P., 2016-06-20 Blended learning has gained significant attention recently by educational leaders, practitioners, and researchers. i²Flex, a variation of blended learning, is based on the premise that certain non-interactive teaching activities, such as lecturing, can take place by students without teachers’ direct involvement. Classroom time can then be used for educational activities that fully exploit teacher-student and student-student interactions, allowing for meaningful personalized feedback and scaffolding on demand. Revolutionizing K-12 Blended Learning through the i²Flex Classroom Model presents a well-rounded discussion on the i²Flex model, highlighting methods for K-12 course design, delivery, and evaluation in addition to teacher performance assessment in a blended i²Flex environment. Emphasizing new methods for improving the classroom and learning experience in addition to preparing students for higher education and careers, this publication is an essential reference source for pre-service and in-service teachers, researchers, administrators, and educational technology developers. |
| the cell cycle and cancer virtual lab: Human Biology Sylvia S. Mader, 2008 The relationship between humans and other living things is emphasised in this text. Students are provided with a firm grasp of how their bodies function and how the human population can become more fully integrated into the biosphere. |
| the cell cycle and cancer virtual lab: Glencoe Biology, Student Edition McGraw-Hill Education, 2016-06-06 |
| the cell cycle and cancer virtual lab: The Cell Cycle David Owen Morgan, 2007 Cell division is a central biological process: it yields the cells required for development and growth, and supplies the replacement cells to repair and maintain old or damaged tissue. This book gives the students a complete overview of the process of cell division - from chromosome division, through mitosis, cytokinesis, and meiosis. |
| the cell cycle and cancer virtual lab: Cumulated Index Medicus , 1999 |
| the cell cycle and cancer virtual lab: Concepts of Biology Samantha Fowler, Rebecca Roush, James Wise, 2023-05-12 Black & white print. Concepts of Biology is designed for the typical introductory biology course for nonmajors, covering standard scope and sequence requirements. The text includes interesting applications and conveys the major themes of biology, with content that is meaningful and easy to understand. The book is designed to demonstrate biology concepts and to promote scientific literacy. |
| the cell cycle and cancer virtual lab: Virtual Drug Design Daniela Schuster, Honglin Li, 2020-01-13 In the current drug research environment in academia and industry, cheminformatics and virtual screening methods are well established and integrated tools. Computational tools are used to predict a compound’s 3D structure, the 3D structure and function of a pharmacological target, ligand-target interactions, binding energies, and other factors essential for a successful drug. This includes molecular properties such as solubility, logP value, susceptibility to metabolism, cell permeation, blood brain barrier permeation, interaction with drug transporters and potential off-target effects. Given that approximately 40 million unique compounds are readily available for purchase, such computational modeling and filtering tools are essential to support the drug discovery and development process. The aim of all these calculations is to focus experimental efforts on the most promising candidates and exclude problematic compounds early in the project. In this Research Topic on virtual activity predictions, we cover several aspects of this research area such as historical perspectives, data sources, ligand treatment, virtual screening methods, hit list handling and filtering. |
| the cell cycle and cancer virtual lab: Cytotoxicity - Definition, Identification, and Cytotoxic Compounds Hasan Basri Ila, Erman Salih Istifli, 2019 Compensating for cytotoxicity in the multicellular organism by a certain level of cellular proliferation is the primary aim of homeostasis. In addition, the loss of cellular proliferation control (tumorigenesis) is at least as important as cytotoxicity, however, it is a contrasting trauma. With the disruption of the delicate balance between cytotoxicity and proliferation, confrontation with cancer can inevitably occur. This book presents important information pertaining to the molecular control of the mechanisms of cytotoxicity and cellular proliferation as they relate to cancer. It is designed for students and researchers studying cytotoxicity and its control. |
| the cell cycle and cancer virtual lab: The Comprehensive Cancer Center Mahmoud Aljurf, Navneet S. Majhail, Mickey B.C. Koh, Mohamed A. Kharfan-Dabaja, Nelson J. Chao, 2021-10-28 This open access book provides a valuable resource for hospitals, institutions, and health authorities worldwide in their plans to set up and develop comprehensive cancer care centers. The development and implementation of a comprehensive cancer program allows for a systematic approach to evidence-based strategies of prevention, early detection, diagnosis, treatment, and palliation. Comprehensive cancer programs also provide a nexus for the running of clinical trials and implementation of novel cancer therapies with the overall aim of optimizing comprehensive and holistic care of cancer patients and providing them with the best opportunity to improve quality of life and overall survival. This book's self-contained chapter format aims to reinforce the critical importance of comprehensive cancer care centers while providing a practical guide for the essential components needed to achieve them, such as operational considerations, guidelines for best clinical inpatient and outpatient care, and research and quality management structures. Intended to be wide-ranging and applicable at a global level for both high and low income countries, this book is also instructive for regions with limited resources. The Comprehensive Cancer Center: Development, Integration, and Implementation is an essential resource for oncology physicians including hematologists, medical oncologists, radiation oncologists, surgical oncologists, and oncology nurses as well as hospitals, health departments, university authorities, governments and legislators. |
| the cell cycle and cancer virtual lab: Cell Cycle Regulation Philipp Kaldis, 2006-06-26 This book is a state-of-the-art summary of the latest achievements in cell cycle control research with an outlook on the effect of these findings on cancer research. The chapters are written by internationally leading experts in the field. They provide an updated view on how the cell cycle is regulated in vivo, and about the involvement of cell cycle regulators in cancer. |
| the cell cycle and cancer virtual lab: Plant Cryopreservation: A Practical Guide Barbara B.M. Reed, 2007-10-31 Cryopreservation has proven to be an important tool for the storage and conservation of plant genetic resources. This book is a unique resource for plant scientists, providing more than 100 ready-to-use cryopreservation protocols for plant types from algae and bryophytes to a range of flowering plants. It includes techniques for diverse plant parts such as dormant buds, pollen, and apical meristems and for cell types such as suspension and callus cultures. |
| the cell cycle and cancer virtual lab: Mitosis/Cytokinesis Arthur Zimmerman, 2012-12-02 Mitosis/Cytokinesis provides a comprehensive discussion of the various aspects of mitosis and cytokinesis, as studied from different points of view by various authors. The book summarizes work at different levels of organization, including phenomenological, molecular, genetic, and structural levels. The book is divided into three sections that cover the premeiotic and premitotic events; mitotic mechanisms and approaches to the study of mitosis; and mechanisms of cytokinesis. The authors used a uniform style in presenting the concepts by including an overview of the field, a main theme, and a conclusion so that a broad range of biologists could understand the concepts. This volume also explores the potential developments in the study of mitosis and cytokinesis, providing a background and perspective into research on mitosis and cytokinesis that will be invaluable to scientists and advanced students in cell biology. The book is an excellent reference for students, lecturers, and research professionals in cell biology, molecular biology, developmental biology, genetics, biochemistry, and physiology. |
| the cell cycle and cancer virtual lab: The Heterogeneity of Cancer Metabolism Anne Le, 2018-06-26 Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies. |
| the cell cycle and cancer virtual lab: The Plant Cell Cycle Dirk Inzé, 2011-06-27 In recent years, the study of the plant cell cycle has become of major interest, not only to scientists working on cell division sensu strictu , but also to scientists dealing with plant hormones, development and environmental effects on growth. The book The Plant Cell Cycle is a very timely contribution to this exploding field. Outstanding contributors reviewed, not only knowledge on the most important classes of cell cycle regulators, but also summarized the various processes in which cell cycle control plays a pivotal role. The central role of the cell cycle makes this book an absolute must for plant molecular biologists. |
| the cell cycle and cancer virtual lab: The Emperor of All Maladies Siddhartha Mukherjee, 2011-08-09 Selected as One of the Best Books of the 21st Century by The New York Times Winner of the Pulitzer Prize, adapted as a documentary from Ken Burns on PBS, this New York Times bestseller is “an extraordinary achievement” (The New Yorker)—a magnificent, profoundly humane “biography” of cancer. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer. |
| the cell cycle and cancer virtual lab: Computational and Experimental Fluid Mechanics with Applications to Physics, Engineering and the Environment Leonardo Di G. Sigalotti, Jaime Klapp, Eloy Sira, 2014-01-11 The book presents a collection of selected papers from the I Workshop of the Venezuelan Society of Fluid Mechanics held on Margarita Island, Venezuela from November 4 to 9, 2012. Written by experts in their respective fields, the contributions are organized into five parts: - Part I Invited Lectures, consisting of full-length technical papers on both computational and experimental fluid mechanics covering a wide range of topics from drops to multiphase and granular flows to astrophysical flows, - Part II Drops, Particles and Waves - Part III Multiphase and Multicomponent Flows - Part IV Atmospheric and Granular Flows - and Part V Turbulent and Astrophysical Flows. The book is intended for upper-level undergraduate and graduate students as well as for physicists, chemists and engineers teaching and working in the field of fluid mechanics and its applications. The contributions are the result of recent advances in theoretical and experimental research in fluid mechanics, encompassing both fundamentals as well as applications to fluid engineering design, including pipelines, turbines, flow separators, hydraulic systems and biological fluid elements, and to granular, environmental and astrophysical flows. |
| the cell cycle and cancer virtual lab: Resistance to Immunotherapeutic Antibodies in Cancer Benjamin Bonavida, 2013-08-04 The traditional approaches to treat various cancers include chemotherapy, radiation and/or hormonal therapy. While these therapies continue to be effective in large part, they are not selective and highly toxic. There have been encouraging results in alternative therapeutic approach called antibody-mediated anti-cancer therapy, which is less toxic, more selective, and can also reverse drug/radiation resistance. Monoclonal antibodies or mAbs can be used to destroy malignant tumor cells and prevent tumor growth by blocking specific cell receptors. mAbs can bind only to cancer cell-specific antigens and induce an immunological response against the target cancer cell. The book covers the common and unique features of mAbs agains various cancer, gives the latest developments on the molecular, biochemical and genetic mechanisms of resistance by various mAbs, as well as discuss novel mAbs to overcome resistance. |
| the cell cycle and cancer virtual lab: Membranes and Transport Anthony N. Martonosi, 1982-08-31 This work is a collection of short reviews on membranes and transport. It portrays the field as a mosaic of bright little pieces, which are interesting in themselves but gain full signif icance when viewed as a whole. Traditional boundaries are set aside and biochemists, biophysicists, physiologists, and cell biologists enter into a natural discourse. The principal motivation of this work was to ease the problems of communication that arose from the explosive growth and interdisciplinary character of membrane research. In these volumes we hope to provide a readily available comprehensive source of critical information covering many of the exciting, recent developments on the structure, biosyn thesis, and function of biological membranes in microorganisms, animal cells, and plants. The 182 reviews contributed by leading authorities should enable experts to check up on recent developments in neighboring areas of research, allow teachers to organize material for membrane and transport courses, and give advanced students the opportunity to gain a broad view of the topic. Special attention was given to developments that are expected to open new areas of investigation. The result is a kaleidoscope of facts, viewpoints, theories, and techniques, which radiates the excitement of this important field. Publication of these status reports every few years should enable us to follow progress in an interesting and easygoing format. I am grateful to the authors, to Plenum Publishing Corporation, and to several of my colleagues for their thoughtful suggestions and enthusiastic cooperation, which made this work possible. |
| the cell cycle and cancer virtual lab: Cancer Cell Metabolism , 2020 This book illustrates various aspects of cancer cell metabolism, including metabolic regulation in solid tumours vs. non-solid tumours, the molecular pathways involved in its metabolism, and the role of the tumour microenvironment in the regulation of cancer cell metabolism. It summarizes the complexity of cancer cell metabolism in terms of the switch from anaerobic to aerobic glycolysis and how mitochondrial damage promotes aerobic glycolysis in cancer cells. The respective chapters provide the latest information on the metabolic remodelling of cancer cells and elucidate the important role of the signalling pathways in reprogramming of cancer cell metabolism. In addition, the book highlights the role of autophagy in cancer cell metabolism, and how metabolic crosstalk between cancer cells and cancer-associated fibroblasts promotes cancer cell progression. In closing, it summarizes recent advancements in drug development through targeting cancer metabolism. |
| the cell cycle and cancer virtual lab: The Drug Development Paradigm in Oncology National Academies of Sciences, Engineering, and Medicine, Health and Medicine Division, Board on Health Care Services, National Cancer Policy Forum, 2018-02-12 Advances in cancer research have led to an improved understanding of the molecular mechanisms underpinning the development of cancer and how the immune system responds to cancer. This influx of research has led to an increasing number and variety of therapies in the drug development pipeline, including targeted therapies and associated biomarker tests that can select which patients are most likely to respond, and immunotherapies that harness the body's immune system to destroy cancer cells. Compared with standard chemotherapies, these new cancer therapies may demonstrate evidence of benefit and clearer distinctions between efficacy and toxicity at an earlier stage of development. However, there is a concern that the traditional processes for cancer drug development, evaluation, and regulatory approval could impede or delay the use of these promising cancer treatments in clinical practice. This has led to a number of effortsâ€by patient advocates, the pharmaceutical industry, and the Food and Drug Administration (FDA)â€to accelerate the review of promising new cancer therapies, especially for cancers that currently lack effective treatments. However, generating the necessary data to confirm safety and efficacy during expedited drug development programs can present a unique set of challenges and opportunities. To explore this new landscape in cancer drug development, the National Academies of Sciences, Engineering, and Medicine developed a workshop held in December 2016. This workshop convened cancer researchers, patient advocates, and representatives from industry, academia, and government to discuss challenges with traditional approaches to drug development, opportunities to improve the efficiency of drug development, and strategies to enhance the information available about a cancer therapy throughout its life cycle in order to improve its use in clinical practice. This publication summarizes the presentations and discussions from the workshop. |
| the cell cycle and cancer virtual lab: Cells Benjamin Lewin, 2007 CELLS, the most cutting-edge textbook in the field, is the ideal resource for advanced undergraduate and graduate students entering the world of cell biology, and is a useful tool for scientists who wish to learn more about topics outside their field. This important new text provides full coverage of the structure, organization, growth, regulation, movements, and interaction of cells, with an emphasis on eukaryotic cells. Where they are known, the molecular bases for human diseases are discussed in each chapter.Under the direction of Dr. Benjamin Lewin and three expert lead editors, each chapter was prepared by top scientists who specialize in the subject area. All chapters were carefully edited to maintain consistent use of terminology and to achieve a homogeneous level of detail and rigor.--Publisher's website. |
| the cell cycle and cancer virtual lab: Males With Eating Disorders Arnold E. Andersen, 2014-06-17 First published in 1990. The subject of anorexia nervosa and, more recently, bulimia nervosa in males has been a source of interest and controversy in the fields of psychiatry and medicine for more than 300 years. These disorders, sometimes called eating disorders, raise basic questions concerning the nature of abnormalities of the motivated behaviors: Are they subsets of more widely recognized illnesses such as mood disorders? Are they understandable by reference to underlying abnormalities of biochemistry or brain function? In what ways are they similar to and in what ways do they differ from anorexia nervosa and bulimia nervosa in females? This book will be of interest to a wide variety of people—physicians, psychologists, nurses, social workers, occupational therapists, nutritionists, educators, and all others who may be interested for personal or professional reasons. |
| the cell cycle and cancer virtual lab: Cancer and Aging M. Extermann, 2013-01-18 Cancer is clearly an age-related disease. Recent research in both aging and cancer has demonstrated the complex interaction between the two phenomena. This affects a wide spectrum of research and practice, anywhere from basic research to health care organization. Core examples of these close associations are addressed in this book. Starting with basic research, the first chapters cover cancer development, mTOR inhibition, senescent cells altering the tumor microenvironment, and immune senescence affecting cancer vaccine response. Taking into account the multidisciplinarity of geriatric oncology, several chapters focus on geriatric and oncologic aspects in patient assessment, treatment options, nursing and exercise programs. The book is rounded off by a discussion on the impact of the metabolic syndrome illustrating the interactions between comorbidity and cancer and a chapter on frailty.This book provides the reader with insights that will hopefully foster his or her reflection in their own research and practice to further the development of this most exciting field. Given the aging of the population worldwide and the high prevalence of cancer, it is essential reading not only for oncologists and geriatricians but for all health practitioners. |
| the cell cycle and cancer virtual lab: New Challenges for Cancer Systems Biomedicine Alberto D'Onofrio, Paola Cerrai, Alberto Gandolfi, 2013-01-25 The future of oncology seems to lie in Molecular Medicine (MM). MM is a new science based on three pillars. Two of them are evident in its very name and are well known: medical science and molecular biology. However, there is a general unawareness that MM is firmly based on a third, and equally important, pillar: Systems Biomedicine. Currently, this term denotes multilevel, hierarchical models integrating key factors at the molecular, cellular, tissue, through phenotype levels, analyzed to reveal the global behavior of the biological process under consideration. It becomes increasingly evident that the tools to construct such complex models include, not only bioinformatics and modern applied statistics, as is unanimously agreed, but also other interdisciplinary fields of science, notably, Mathematical Oncology, Systems Biology and Theoretical Biophysics. |
| the cell cycle and cancer virtual lab: Index Medicus , 2004 Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings. |
| the cell cycle and cancer virtual lab: Organelle and Molecular Targeting Lara Scheherazade Milane, Mansoor M. Amiji, 2021-12-27 We have surpassed the omics era and are truly in the Age of Molecular Therapeutics. The fast-paced development of SARS-CoV-2 vaccines, such as the mRNA vaccines encoding the viral spike protein, demonstrated the need for and capability of molecular therapy and nanotechnology-based solutions for drug delivery. In record speed, the SARS-CoV-2 viral RNA genome was sequenced and shared with the scientific community, allowing the rapid design of molecular therapeutics. The mRNA vaccines exploit the host cell endoplasmic reticulum to produce viral spike proteins for antigen presentation and recognition by the innate and adaptive immune system. Lipid nanoparticles enable the delivery of the fragile, degradation-sensitive nucleic acid payloads. Molecular-based therapeutics and nanotechnology solutions continue to drive the scientific and medical response to the COVID-19 pandemic as new mRNA, DNA, and protein-based vaccines are developed and approved and the emergency use approved vaccines are rapidly manufactured and distributed throughout the globe. The need for molecular therapies and drug delivery solutions is clear, and as these therapies progress and become more specialized there will be important advancements in organelle targeting. For example, using organelle targeting to direct lipid nanoparticles with mRNA payloads to the endoplasmic reticulum would increase the efficacy of mRNA vaccines, reducing the required dose and therefore the biomanufacturing demand. Likewise, improving the delivery of DNA therapeutics to the nucleus would improve efficacy. Organelles and molecules have always been drug targets, but until recently we have not had the tools or capability to design and develop such highly specific therapeutics. Organelle targeting has far-reaching implications. For example, mitochondria are central to both energy production and intrinsic apoptosis. Effectively targeting and manipulating mitochondria has therapeutic applications for diseases such as myopathies, cancer, neurodegeneration, progerias, diabetes, and the natural aging process. The SARS-CoV-2 vaccines that exploit the endoplasmic reticulum (for mRNA vaccines) and the nucleic translational process (DNA vaccines) attest to the need for organelle and molecular therapeutics. This book covers the status, demand, and future of organelle- and molecularly targeted therapeutics that are critical to the advancement of modern medicine. Organelle and molecular targeting is the drug design and drug delivery approach of today and the future; understanding this approach is essential for students, scientists, and clinicians contributing to modern medicine. |
| the cell cycle and cancer virtual lab: Cancer Evolution Charles Swanton, 2017 Tumor progression is driven by mutations that confer growth advantages to different subpopulations of cancer cells. As a tumor grows, these subpopulations expand, accumulate new mutations, and are subjected to selective pressures from the environment, including anticancer interventions. This process, termed clonal evolution, can lead to the emergence of therapy-resistant tumors and poses a major challenge for cancer eradication efforts. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine examines cancer progression as an evolutionary process and explores how this way of looking at cancer may lead to more effective strategies for managing and treating it. The contributors review efforts to characterize the subclonal architecture and dynamics of tumors, understand the roles of chromosomal instability, driver mutations, and mutation order, and determine how cancer cells respond to selective pressures imposed by anticancer agents, immune cells, and other components of the tumor microenvironment. They compare cancer evolution to organismal evolution and describe how ecological theories and mathematical models are being used to understand the complex dynamics between a tumor and its microenvironment during cancer progression. The authors also discuss improved methods to monitor tumor evolution (e.g., liquid biopsies) and the development of more effective strategies for managing and treating cancers (e.g., immunotherapies). This volume will therefore serve as a vital reference for all cancer biologists as well as anyone seeking to improve clinical outcomes for patients with cancer. |
| the cell cycle and cancer virtual lab: Pancreas Shailesh V. Shrikhande, Markus Büchler, 2022 Gastrointestinal surgery (GI) is performed for a range of benign and malignant diseases in both elective and emergency settings. This volume covers the surgery and management of the pancreas, including acute and chronic pancreatitis and pancreatic cancer. |
| the cell cycle and cancer virtual lab: Computational Intelligence Methods for Bioinformatics and Biostatistics Andrea Bracciali, Giulio Caravagna, David Gilbert, Roberto Tagliaferri, 2017-10-14 This book constitutes the thoroughly refereed post-conference proceedings of the 13th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics, CIBB 2016, held in Stirling, UK, in September 2016. The 19 revised full papers and 6 keynotes abstracts presented were carefully reviewed and selected from 61 submissions. The papers deal with the application of computational intelligence to open problems in bioinformatics, biostatistics, systems and synthetic biology, medicalinformatics, computational approaches to life sciences in general |
| the cell cycle and cancer virtual lab: Serious Games Analytics Christian Sebastian Loh, Yanyan Sheng, Dirk Ifenthaler, 2015-06-18 This volume brings together research on how gameplay data in serious games may be turned into valuable analytics or actionable intelligence for performance measurement, assessment, and improvement. Chapter authors use empirical research methodologies, including existing, experimental, and emerging conceptual frameworks, from various fields, such as: computer science software engineering educational data mining statistics information visualization. Serious games is an emerging field where the games are created using sound learning theories and instructional design principles to maximize learning and training success. But how would stakeholders know what play-learners have done in the game environment, and if the actions performance brings about learning? Could they be playing the game for fun, really learning with evidence of performance improvement, or simply gaming the system, i.e., finding loopholes to fake that they are making progress? This volume endeavors to answer these questions. |
| the cell cycle and cancer virtual lab: Radical Kate Pickert, 2019-10-01 In this powerful and unflinching page-turner (New York Times), a healthcare journalist examines the science, history, and culture of breast cancer. As a health-care journalist, Kate Pickert knew the emotional highs and lows of medical treatment well -- but always from a distance, through the stories of her subjects. That is, until she was unexpectedly diagnosed with an aggressive type of breast cancer at the age of 35. As she underwent more than a year of treatment, Pickert realized that the popular understanding of breast care in America bears little resemblance to the experiences of today's patients and the rapidly changing science designed to save their lives. After using her journalistic skills to navigate her own care, Pickert embarked on a quest to understand the cultural, scientific and historical forces shaping the lives of breast-cancer patients in the modern age. Breast cancer is one of history's most prolific killers. Despite billions spent on research and treatments, it remains one of the deadliest diseases facing women today. From the forests of the Pacific Northwest to an operating suite in Los Angeles to the epicenter of pink-ribbon advocacy in Dallas, Pickert reports on the turning points and people responsible for the progress that has been made against breast cancer and documents the challenges of defeating a disease that strikes one in eight American women and has helped shape the country's medical culture. Drawing on interviews with doctors, economists, researchers, advocates and patients, as well as on journal entries and recordings collected over the author's treatment, Radical puts the story of breast cancer into context, and shows how modern treatments represent a long overdue shift in the way doctors approach cancer -- and disease -- itself. |
| the cell cycle and cancer virtual lab: Pathology of Malignant Mesothelioma Francoise Galateau-Sallé, 2010-05-06 • Only up-to-date title in the market • Current topic with significant media coverage • Internationally relevant, the use of asbestos and its consequences is a global problem • This title aids in pathological diagnosis which is very difficult • Contributors are experts from France, UK, USA, Australia and Canada • Plentiful, colored illustrations complete the text • Target group exceeds pathologists: The diagnosis is evidence for medico-legal purposes, which makes the book invaluable to members of legal profession specializing in this disease |
| the cell cycle and cancer virtual lab: Laboratory Manual for Anatomy & Physiology featuring Martini Art, Cat Version Michael G. Wood, 2012-02-27 This is the eBook of the printed book and may not include any media, website access codes, or print supplements that may come packaged with the bound book. Known for its carefully guided lab activities, accurate art and photo program, and unique practice and review tools that encourage students to draw, label, apply clinical content, and think critically, Wood, Laboratory Manual for Anatomy & Physiology featuring Martini Art , Cat Version, Fifth Edition offers a comprehensive approach to the two-semester A&P laboratory course. The stunning, full-color illustrations are adapted from Martini/Nath/Bartholomew, Fundamentals of Anatomy & Physiology, Ninth Edition, making this lab manual a perfect companion to that textbook for instructors who want lab manual art to match textbook art. The use of the Martini art also makes this lab manual a strong companion to Martini/Ober/Nath, Visual Anatomy & Physiology. This manual can also be used with any other two-semester A&P textbook for those instructors who want students in the lab to see different art from what is in their textbook. This lab manual is available in three versions: Main, Cat, and Pig. The Cat and Pig versions are identical to the Main version but also include nine cat or pig dissection exercises at the back of the lab manual. The Fifth Edition features more visually effective art and abundant opportunities for student practice in the manual. This package contains: Laboratory Manual for Anatomy & Physiology featuring Martini Art, Cat Version, Fifth Edition |
| the cell cycle and cancer virtual lab: Genome Stability Igor Kovalchuk, Olga Kovalchuk, 2021-07-17 Genome Stability: From Virus to Human Application, Second Edition, a volume in the Translational Epigenetics series, explores how various species maintain genome stability and genome diversification in response to environmental factors. Here, across thirty-eight chapters, leading researchers provide a deep analysis of genome stability in DNA/RNA viruses, prokaryotes, single cell eukaryotes, lower multicellular eukaryotes, and mammals, examining how epigenetic factors contribute to genome stability and how these species pass memories of encounters to progeny. Topics also include major DNA repair mechanisms, the role of chromatin in genome stability, human diseases associated with genome instability, and genome stability in response to aging. This second edition has been fully revised to address evolving research trends, including CRISPRs/Cas9 genome editing; conventional versus transgenic genome instability; breeding and genetic diseases associated with abnormal DNA repair; RNA and extrachromosomal DNA; cloning, stem cells, and embryo development; programmed genome instability; and conserved and divergent features of repair. This volume is an essential resource for geneticists, epigeneticists, and molecular biologists who are looking to gain a deeper understanding of this rapidly expanding field, and can also be of great use to advanced students who are looking to gain additional expertise in genome stability. - A deep analysis of genome stability research from various kingdoms, including epigenetics and transgenerational effects - Provides comprehensive coverage of mechanisms utilized by different organisms to maintain genomic stability - Contains applications of genome instability research and outcomes for human disease - Features all-new chapters on evolving areas of genome stability research, including CRISPRs/Cas9 genome editing, RNA and extrachromosomal DNA, programmed genome instability, and conserved and divergent features of repair |
| the cell cycle and cancer virtual lab: Ecology and Evolution of Cancer Beata Ujvari, Frdric Thomas, Benjamin Roche, 2017-03-10 The Ecology and Evolution of Cancer is a timely work outlining ideas that not only represent a substantial and original contribution to the fields of evolution, ecology and cancer, but also goes beyond by connecting the interface of these disciplines. This work engages the expertise of a multidisciplinary research team to collate and review the latest knowledge and development of this exciting research field. The evolutionary perspective of cancer has gained significant international recognition and interest, which is fully understandable given that somatic cellular selection and evolution are elegant explanations for carcinogenesis. Cancer is now generally accepted to be an evolutionary and ecological process with complex interactions between tumor cells and their environment sharing many similarities with organismal evolution. As a critical contribution to this field of research, The Ecology and Evolution of Cancer is important and relevant for the applications of evolutionary biology to understand the origin of cancers, to control neoplastic progression and to prevent therapeutic failures. Covers all aspects of the evolution of cancer, appealing to researchers seeking to understand its origins and effects of treatments on its progression, as well as lecturers in evolutionary medicine Functions as both an introduction to cancer and evolution and a review of the current research on this burgeoning, exciting field, presented by an international group of leading editors and contributors Improves understanding of the origin and the evolution of cancer, aiding efforts to determine how this disease interferes with biotic interactions that govern ecosystems Highlights research that intends to apply evolutionary principles to help predict emergence and metastatic progression with the aim of improving therapies |
Cell: Cell - Cell Press
Cell publishes findings of unusual significance in any area of experimental biology, including but not limited to cell biology, molecular biology, …
Cell (biology) - Wikipedia
The cell is the basic structural and functional unit of all forms of life. Every cell consists of cytoplasm enclosed within a membrane; many cells …
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Apr 25, 2025 · cell, in biology, the basic membrane-bound unit that contains the fundamental molecules of life and of which all living things are …
The cell: Types, functions, and organelles - Medical News To…
Dec 19, 2023 · A cell is the smallest living organism and the basic unit of life on earth. Together, trillions of cells make up the human body. Cells have …
Cell – Definition, Structure, Types, Functions, Examples
Apr 7, 2024 · A cell is the basic structural and functional unit of all living organisms, responsible for various life processes and …
Cell: Cell - Cell Press
Cell publishes findings of unusual significance in any area of experimental biology, including but not limited to cell biology, molecular biology, neuroscience, immunology, virology and …
Cell (biology) - Wikipedia
The cell is the basic structural and functional unit of all forms of life. Every cell consists of cytoplasm enclosed within a membrane; many cells contain organelles, each with a specific …
Cell | Definition, Types, Functions, Diagram, Division, Theory,
Apr 25, 2025 · cell, in biology, the basic membrane-bound unit that contains the fundamental molecules of life and of which all living things are composed. A single cell is often a complete …
The cell: Types, functions, and organelles - Medical News Today
Dec 19, 2023 · A cell is the smallest living organism and the basic unit of life on earth. Together, trillions of cells make up the human body. Cells have three parts: the membrane, the nucleus, …
Cell – Definition, Structure, Types, Functions, Examples
Apr 7, 2024 · A cell is the basic structural and functional unit of all living organisms, responsible for various life processes and containing essential biological
What Is a Cell? | Learn Science at Scitable - Nature
All cells evolved from a common ancestor and use the same kinds of carbon-based molecules. Learn how cell function depends on a diverse group of nucleic acids, proteins, lipids, and sugars.
What is a cell? - MedlinePlus
Feb 22, 2021 · Cells are the basic building blocks of all living things. The human body is composed of trillions of cells. They provide structure for the body, take in nutrients from food, …
Cell Definition - BYJU'S
Jan 14, 2018 · Cells are the structural, functional, and biological units of all living beings. A cell can replicate itself independently. Hence, they are known as the building blocks of life. Each …
Chapter 6. Cell Structure and Function – Human Anatomy and …
Describe the general characteristics of each of the following cell types and relate their characteristics to their functions: nerve cell, muscle cell, red blood cell (erythrocyte), and white …
Introduction to cells - Basic Biology
Aug 30, 2020 · A cell is the simplest unit of life and they are responsible for keeping an organism alive and functioning. This introduction to cells is the starting point for the area of biology that …
