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| the laws of medicine siddhartha mukherjee free download: The Laws of Medicine Siddhartha Mukherjee, 2015-10-13 Essential, required reading for doctors and patients alike: A Pulitzer Prize-winning author and one of the world’s premiere cancer researchers reveals an urgent philosophy on the little-known principles that govern medicine—and how understanding these principles can empower us all. Over a decade ago, when Siddhartha Mukherjee was a young, exhausted, and isolated medical resident, he discovered a book that would forever change the way he understood the medical profession. The book, The Youngest Science, forced Dr. Mukherjee to ask himself an urgent, fundamental question: Is medicine a “science”? Sciences must have laws—statements of truth based on repeated experiments that describe some universal attribute of nature. But does medicine have laws like other sciences? Dr. Mukherjee has spent his career pondering this question—a question that would ultimately produce some of most serious thinking he would do around the tenets of his discipline—culminating in The Laws of Medicine. In this important treatise, he investigates the most perplexing and illuminating cases of his career that ultimately led him to identify the three key principles that govern medicine. Brimming with fascinating historical details and modern medical wonders, this important book is a fascinating glimpse into the struggles and Eureka! moments that people outside of the medical profession rarely see. Written with Dr. Mukherjee’s signature eloquence and passionate prose, The Laws of Medicine is a critical read, not just for those in the medical profession, but for everyone who is moved to better understand how their health and well-being is being treated. Ultimately, this book lays the groundwork for a new way of understanding medicine, now and into the future. |
| the laws of medicine siddhartha mukherjee free download: The Emperor of All Maladies Siddhartha Mukherjee, 2011-08-09 Selected as One of the Best Books of the 21st Century by The New York Times Winner of the Pulitzer Prize, adapted as a documentary from Ken Burns on PBS, this New York Times bestseller is “an extraordinary achievement” (The New Yorker)—a magnificent, profoundly humane “biography” of cancer. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer. |
| the laws of medicine siddhartha mukherjee free download: Good Economics for Hard Times Abhijit V. Banerjee, Esther Duflo, 2019-11-12 The winners of the Nobel Prize show how economics, when done right, can help us solve the thorniest social and political problems of our day. Figuring out how to deal with today's critical economic problems is perhaps the great challenge of our time. Much greater than space travel or perhaps even the next revolutionary medical breakthrough, what is at stake is the whole idea of the good life as we have known it. Immigration and inequality, globalization and technological disruption, slowing growth and accelerating climate change--these are sources of great anxiety across the world, from New Delhi and Dakar to Paris and Washington, DC. The resources to address these challenges are there--what we lack are ideas that will help us jump the wall of disagreement and distrust that divides us. If we succeed, history will remember our era with gratitude; if we fail, the potential losses are incalculable. In this revolutionary book, renowned MIT economists Abhijit V. Banerjee and Esther Duflo take on this challenge, building on cutting-edge research in economics explained with lucidity and grace. Original, provocative, and urgent, Good Economics for Hard Times makes a persuasive case for an intelligent interventionism and a society built on compassion and respect. It is an extraordinary achievement, one that shines a light to help us appreciate and understand our precariously balanced world. |
| the laws of medicine siddhartha mukherjee free download: The Gene Siddhartha Mukherjee, 2016-05-17 The #1 NEW YORK TIMES Bestseller The basis for the PBS Ken Burns Documentary The Gene: An Intimate History Now includes an excerpt from Siddhartha Mukherjee’s new book Song of the Cell! From the Pulitzer Prize–winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). “Sid Mukherjee has the uncanny ability to bring together science, history, and the future in a way that is understandable and riveting, guiding us through both time and the mystery of life itself.” —Ken Burns “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost” (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” (The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “The Gene is a book we all should read” (USA TODAY). |
| the laws of medicine siddhartha mukherjee free download: Code Gray Farzon A Nahvi, 2023-02-21 Code Gray is a “provocative and meaningful” (Theresa Brown, New York Times bestselling author of Healing) narrative-driven medical memoir that places you directly in the crucible of urgent life-or-death decision-making, offering insights that can help us cope at a time when the world around us appears to be falling apart. In the tradition of books by such bestselling physician-authors as Atul Gawande, Siddhartha Mukherjee, and Danielle Ofri, this beautifully written memoir by an emergency room doctor revolves around one of his routine shifts at an urban ER. Intimately narrated as it follows the experiences of real patients, it is filled with fascinating, adrenaline-pumping scenes of rescues and deaths, and the critical, often excruciating follow-through in caring for patients’ families. Centered on the riveting story of a seemingly healthy forty-three-year-old woman who arrives in the ER in sudden cardiac arrest, Code Gray weaves in stories that explore everything from the early days of the Covid outbreak to the perennial glaring inequities of our healthcare system. It offers an unforgettable, “discomfiting, and often bracing” (Bloomberg Businessweek) portrait of challenges so profound, powerful, and extreme that normal ethical and medical frameworks prove inadequate. By inviting you to experience what it is like to shift in the ER from a physician’s perspective, we are forced to test our beliefs and principles. Often, there are no clear answers to these challenges posed in the ER. You are left feeling unsettled, but through this process, we can appreciate just how complicated, emotional, unpredictable—and yet strikingly beautiful—life can be. |
| the laws of medicine siddhartha mukherjee free download: The Youngest Science Lewis Thomas, 1995-05-01 From the 1920s when he watched his father, a general practitioner who made housecalls and wrote his prescriptions in Latin, to his days in medical school and beyond, Lewis Thomas saw medicine evolve from an art into a sophisticated science. The Youngest Science is Dr. Thomas's account of his life in the medical profession and an inquiry into what medicine is all about--the youngest science, but one rich in possibility and promise. He chronicles his training in Boston and New York, his war career in the South Pacific, his most impassioned research projects, his work as an administrator in hospitals and medical schools, and even his experiences as a patient. Along the way, Thomas explores the complex relationships between research and practice, between words and meanings, between human error and human accomplishment, More than a magnificent autobiography, The Youngest Science is also a celebration and a warning--about the nature of medicine and about the future life of our planet. |
| the laws of medicine siddhartha mukherjee free download: Follow Your Gut Rob Knight, 2015-04-07 Allergies, asthma, obesity, acne: these are just a few of the conditions that may be caused—and someday cured—by the microscopic life inside us. The key is to understand how this groundbreaking science influences your health, mood, and more. In just the last few years, scientists have shown how the microscopic life within our bodies— particularly within our intestines—has an astonishing impact on our lives. Your health, mood, sleep patterns, eating preferences—even your likelihood of getting bitten by mosquitoes—can be traced in part to the tiny creatures that live on and inside of us. In Follow Your Gut, pioneering scientist Rob Knight pairs with award-winning science journalist Brendan Buhler to explain—with good humor and easy-to-grasp examples—why these new findings matter to everyone. They lead a detailed tour of the previously unseen world inside our bodies, calling out the diseases and conditions believed to be most directly impacted by them. With a practical eye toward deeper knowledge and better decisions, they also explore the known effects of antibiotics, probiotics, diet choice and even birth method on our children’s lifelong health. Ultimately, this pioneering book explains how to learn about your own microbiome and take steps toward understanding and improving your health, using the latest research as a guide. |
| the laws of medicine siddhartha mukherjee free download: The Song of the Cell Siddhartha Mukherjee, 2022-11-03 **Longlisted for the Baillie Gifford Prize 2023** A NEW YORK TIMES, DAILY TELEGRAPH, ECONOMIST, MAIL ON SUNDAY and GUARDIAN BOOK OF THE YEAR From the dawn of life itself, every being that has ever lived owes its existence to the cell. 'Will leave you in awe' Guardian The discovery of this vital form led to a transformation in medicine but also in our understanding of ourselves - not as bodies or machines but as ecosystems. It has also given us the power to treat a vast array of mortal maladies...and even to create new kinds of human altogether. Rich with stories of scientists, doctors and the patients whose lives may be saved by their work, The Song of the Cell is a stunning ode to the building blocks of life and the cutting-edge science harnessing their power for the better. 'Profound...As big a topic as life itself' The Times 'Medical magic' Daily Telegraph 'Vast...important...optimistic' Mail on Sunday |
| the laws of medicine siddhartha mukherjee free download: The Legal Right to Housing in India Anindita Mukherjee, 2019-12-12 Examines the benefits of seeking legal recognition for the right to housing, within the Indian legal context. |
| the laws of medicine siddhartha mukherjee free download: Malady of the Mind Jeffrey A. Lieberman, 2023-02-21 “The most important book about schizophrenia in decades, and perhaps ever…a total game-changer.” —Sylvia Nasar, author of A Beautiful Mind A comprehensive, deeply researched, and highly readable portrait of schizophrenia—its history, its various manifestations, and how today’s treatments have promising and often lifesaving potential. This “incredibly captivating” (Siddhartha Mukherjee, author of The Emperor of All Maladies) portrait of schizophrenia, the most malignant and mysterious mental illness, by renowned psychiatrist Jeffrey Lieberman, interweaves cultural and scientific history with dramatic patient profiles and clinical experiences to impart a revolutionary message of hope. For the first time in history, we can effectively treat schizophrenia, limiting its disabling effects—and we’re on the verge of being able to prevent the disease’s onset entirely. Drawing on his four-decade career, Dr. Jeffrey Lieberman expertly illuminates the past, present, and future of this historically dreaded and devastating illness. Interweaving history, science, and policy with personal anecdotes and clinical cases, Malady of the Mind is a rich, illuminating experience written in accessible, fluid prose. From Dr. Lieberman’s vantage point at the pinnacle of academic psychiatry, informed by extensive research experience and clinical care of thousands of patients, he explains how the complexity of the brain, the checkered history of psychiatric medicine, and centuries of stigma combined with misguided legislation and health care policies have impeded scientific advances and clinical progress. Despite this, there is reason for optimism: by offering evidence-based treatments that combine medication with psychosocial services and principles learned from the recovery movement, doctors can now effectively treat schizophrenia by diagnosing patients at a very early stage, achieving a mutually respectful therapeutic alliance, and preventing relapse, thus limiting the progression of the illness. Even more promising, decades of work on diagnosis, detection, and early intervention have pushed scientific progress to the cusp of prevention—meaning that in the near future, doctors may be able to prevent the onset of this disorder. A must-read for those interested in medical history, psychology, and those whose lives have been affected by schizophrenia, this “penetrating, important” (Andrew Solomon, author of Noonday Demon) work offers a comprehensive scientific portrait, crucial insights, sound advice for families and friends, and most importantly, hope for those sufferers now and future generations. |
| the laws of medicine siddhartha mukherjee free download: Tibetan Medicine Rechung Rinpoche, 1973 |
| the laws of medicine siddhartha mukherjee free download: Understanding Patient Safety, Second Edition Robert Wachter, 2012-05-02 Gain a thorough understanding of the key principles of patient safety with the subject's pioneer text -- Now in full color This highly readable yet comprehensive book will appeal to every member of the healthcare team. It is a must for every physician's bookshelf. -- Abraham Verghese, MD, Professor, Stanford University and author of the bestselling Cutting for Stone Bob Wachter's quest to improve the safety of American healthcare represents the very essence of a physician's duty to put the patient first. His unflinching candor about the nature and magnitude of our current safety problems is matched only by his passion for improvement. -- Mark R. Chassin, MD, MPP, MPH, President, The Joint Commission Amazingly readable for such a wealth of important information. This book should be required reading for every health professional and every healthcare executive. -- Christine Cassel, MD, President and CEO, American Board of Internal Medicine In a single volume, Wachter accomplishes the seemingly impossible: furnishing the novice with a highly accessible, easy-to-read introduction to patient safety, while providing a comprehensive, fully annotated reference for the experienced patient safety practitioner. All of the important issues are addressed in individual chapters, each with a lively and relevant clinical example and a “key points” summary at the end bracketing full, balanced and lucid descriptions. A true gem, destined to be a close companion for all of us who strive to make healthcare safe. -- Lucian Leape, MD, Professor, Harvard School of Public Health and Chair, Lucian Leape Institute of the National Patient Safety Foundation There's no more prominent authority on patient safety than Bob Wachter. And there's no more effective primer on patient safety than this one. -- Atul Gawande, MD, MPH, Associate Professor, Harvard Medical School, staff writer for the New Yorker, and bestselling author of Complications and The Checklist Manifesto Compelling: a must read for all concerned with patient safety. Bob Wachter has a unique voice, incorporating clinical experience, research expertise, and policy implications…all with the patient front and center. -- Peter J. Pronovost, MD, PhD, Professor and Director of the Armstrong Institute for Patient Safety and Quality, Johns Hopkins Medicine Understanding Patient Safety, Second Edition is the essential book for anyone seeking to learn the core clinical, organizational, and systems issues of patient safety. Written in an engaging and accessible style by one of the world’s leading authorities on patient safety and quality, Understanding Patient Safety is filled with valuable cases and analyses, as well as tables, graphics, references, and tools. This classic reference is designed to make the patient safety field understandable to medical, nursing, pharmacy, hospital administration, and other trainees, and to be the go-to book for experienced clinicians and non-clinicians alike. The second edition has been revised to include coverage of the latest issues and trends, including: Information technology Measurements of safety, errors, and harm Checklist-based interventions Safety targets Policy issues in patient safety Balancing “no blame” and accountability Understanding Patient Safety, Second Edition delivers key insights to help you understand and prevent a a broad range of errors, including those related to medications, surgery, diagnosis, infections, and nursing care. The crucial contextual issues -- including errors at the person-machine interface, the role of culture, patient engagement in their own safety, and workforce and trainee considerations, are also well covered. Finally, the book provides a practical overview of how to organize an effective safety program, in both hospitals and clinics. |
| the laws of medicine siddhartha mukherjee free download: The Biopsychosocial Model of Health and Disease Derek Bolton, Grant Gillett, 2019-03-28 This open access book is a systematic update of the philosophical and scientific foundations of the biopsychosocial model of health, disease and healthcare. First proposed by George Engel 40 years ago, the Biopsychosocial Model is much cited in healthcare settings worldwide, but has been increasingly criticised for being vague, lacking in content, and in need of reworking in the light of recent developments. The book confronts the rapid changes to psychological science, neuroscience, healthcare, and philosophy that have occurred since the model was first proposed and addresses key issues such as the model’s scientific basis, clinical utility, and philosophical coherence. The authors conceptualise biology and the psychosocial as in the same ontological space, interlinked by systems of communication-based regulatory control which constitute a new kind of causation. These are distinguished from physical and chemical laws, most clearly because they can break down, thus providing the basis for difference between health and disease. This work offers an urgent update to the model’s scientific and philosophical foundations, providing a new and coherent account of causal interactions between the biological, the psychological and social. |
| the laws of medicine siddhartha mukherjee free download: The Four Laws of Debt Free Prosperity Blaine Harris, Charles A. Coonradt, 1996 |
| the laws of medicine siddhartha mukherjee free download: Outstanding Books for the College Bound Angela Carstensen, 2011-05-27 More than simply a vital collection development tool, this book can help librarians help young adults grow into the kind of independent readers and thinkers who will flourish at college. |
| the laws of medicine siddhartha mukherjee free download: The Science of the Art of Medicine J. E. Brush, 2015-11-15 Doctors use reason and probability to assess and treat patients. But given the complexity, uncertainty, and fast pace of real-worldmedical practice, physicians have no choice but to use mental shortcuts and probability estimates as they do their vital work.When doctors deeply understand how they reason, they improve their clinical decision making. This book teaches students,residents, and practicing physicians to think clearly about the logic, probability, and cognitive psychology of medical reasoning.Simple examples, visual explanations, and historical context make the art of how doctors think fascinating and highly relevantto daily medical practice. Reading this book will help you improve the care of your patients, one at a time. |
| the laws of medicine siddhartha mukherjee free download: Understanding Coronavirus Raul Rabadan, 2021-10-14 Since the identification of the first cases of the coronavirus in December 2019, there has been a significant amount of confusion regarding the origin and spread of the so-called 'coronavirus', SARS-CoV-2, and the cause of the disease COVID-19. Conflicting messages from the media and officials across different countries and organizations, the abundance of disparate sources of information, unfounded conspiracy theories on the origins of the virus, unproven therapies, and inconsistent public health measures, have all served to increase anxiety in the population. Where did the virus come from? How is it transmitted? How does it cause disease? Is it like flu? What is a pandemic? In this concise and accessible introduction, a leading expert provides answers to these commonly asked questions. This revised and updated edition now also covers how the virus mutates, how important these mutations are, how vaccines work, and what we can expect in the near and long-term future. |
| the laws of medicine siddhartha mukherjee free download: The Real Doctor Will See You Shortly Matt McCarthy, 2015-04-07 A scorchingly frank look at how doctors are made, bringing readers into the critical care unit to see one burgeoning physician's journey from ineptitude to competence. In medical school, Matt McCarthy dreamed of being a different kind of doctor—the sort of mythical, unflappable physician who could reach unreachable patients. But when a new admission to the critical care unit almost died his first night on call, he found himself scrambling. Visions of mastery quickly gave way to hopes of simply surviving hospital life, where confidence was hard to come by and no amount of med school training could dispel the terror of facing actual patients. This funny, candid memoir of McCarthy’s intern year at a New York hospital provides a scorchingly frank look at how doctors are made, taking readers into patients’ rooms and doctors’ conferences to witness a physician's journey from ineptitude to competence. McCarthy's one stroke of luck paired him with a brilliant second-year adviser he called “Baio” (owing to his resemblance to the Charles in Charge star), who proved to be a remarkable teacher with a wicked sense of humor. McCarthy would learn even more from the people he cared for, including a man named Benny, who was living in the hospital for months at a time awaiting a heart transplant. But no teacher could help McCarthy when an accident put his own health at risk, and showed him all too painfully the thin line between doctor and patient. The Real Doctor Will See You Shortly offers a window on to hospital life that dispenses with sanctimony and self-seriousness while emphasizing the black-comic paradox of becoming a doctor: How do you learn to save lives in a job where there is no practice? |
| the laws of medicine siddhartha mukherjee free download: An American Sickness Elisabeth Rosenthal, 2017-04-11 A New York Times bestseller/Washington Post Notable Book of 2017/NPR Best Books of 2017/Wall Street Journal Best Books of 2017 This book will serve as the definitive guide to the past and future of health care in America.”—Siddhartha Mukherjee, Pulitzer Prize-winning author of The Emperor of All Maladies and The Gene At a moment of drastic political upheaval, An American Sickness is a shocking investigation into our dysfunctional healthcare system - and offers practical solutions to its myriad problems. In these troubled times, perhaps no institution has unraveled more quickly and more completely than American medicine. In only a few decades, the medical system has been overrun by organizations seeking to exploit for profit the trust that vulnerable and sick Americans place in their healthcare. Our politicians have proven themselves either unwilling or incapable of reining in the increasingly outrageous costs faced by patients, and market-based solutions only seem to funnel larger and larger sums of our money into the hands of corporations. Impossibly high insurance premiums and inexplicably large bills have become facts of life; fatalism has set in. Very quickly Americans have been made to accept paying more for less. How did things get so bad so fast? Breaking down this monolithic business into the individual industries—the hospitals, doctors, insurance companies, and drug manufacturers—that together constitute our healthcare system, Rosenthal exposes the recent evolution of American medicine as never before. How did healthcare, the caring endeavor, become healthcare, the highly profitable industry? Hospital systems, which are managed by business executives, behave like predatory lenders, hounding patients and seizing their homes. Research charities are in bed with big pharmaceutical companies, which surreptitiously profit from the donations made by working people. Patients receive bills in code, from entrepreneurial doctors they never even saw. The system is in tatters, but we can fight back. Dr. Elisabeth Rosenthal doesn't just explain the symptoms, she diagnoses and treats the disease itself. In clear and practical terms, she spells out exactly how to decode medical doublespeak, avoid the pitfalls of the pharmaceuticals racket, and get the care you and your family deserve. She takes you inside the doctor-patient relationship and to hospital C-suites, explaining step-by-step the workings of a system badly lacking transparency. This is about what we can do, as individual patients, both to navigate the maze that is American healthcare and also to demand far-reaching reform. An American Sickness is the frontline defense against a healthcare system that no longer has our well-being at heart. |
| the laws of medicine siddhartha mukherjee free download: LGBTQ Social Movements Lisa M. Stulberg, 2018-01-16 In recent years, there has been substantial progress on lesbian, gay, bisexual, transgender, and queer (LGBTQ) civil rights in the United States. We are now, though, in a time of incredible political uncertainty for queer people. LGBTQ Social Movements provides an accessible introduction to mainstream LGBTQ movements in the US, illustrating the many forms that LGBTQ activism has taken since the mid-twentieth century. Covering a range of topics, including the Stonewall uprising and gay liberation, AIDS politics, queer activism, marriage equality fights, youth action, and bisexual and transgender justice, Lisa M. Stulberg explores how marginalized people and communities have used a wide range of political and cultural tools to demand and create change. The five key themes that guide the book are assimilationism and liberationism as complex strategies for equality, the limits and possibilities of legal change, the role of art and popular culture in social change, the interconnectedness of social movements, and the role of privilege in movement organizing. This book is an important tool for understanding current LGBTQ politics and will be essential reading for students and scholars of sexuality, LGBTQ studies, and social movements, as well as anyone new to thinking about these issues. |
| the laws of medicine siddhartha mukherjee free download: Big Data Security Shibakali Gupta, Indradip Banerjee, Siddhartha Bhattacharyya, 2019-10-08 After a short description of the key concepts of big data the book explores on the secrecy and security threats posed especially by cloud based data storage. It delivers conceptual frameworks and models along with case studies of recent technology. |
| the laws of medicine siddhartha mukherjee free download: Chasing My Cure David Fajgenbaum, 2019-09-10 LOS ANGELES TIMES AND PUBLISHERS WEEKLY BESTSELLER • The powerful memoir of a young doctor and former college athlete diagnosed with a rare disease who spearheaded the search for a cure—and became a champion for a new approach to medical research. “A wonderful and moving chronicle of a doctor’s relentless pursuit, this book serves both patients and physicians in demystifying the science that lies behind medicine.”—Siddhartha Mukherjee, New York Times bestselling author of The Emperor of All Maladies and The Gene David Fajgenbaum, a former Georgetown quarterback, was nicknamed the Beast in medical school, where he was also known for his unmatched mental stamina. But things changed dramatically when he began suffering from inexplicable fatigue. In a matter of weeks, his organs were failing and he was read his last rites. Doctors were baffled by his condition, which they had yet to even diagnose. Floating in and out of consciousness, Fajgenbaum prayed for a second chance, the equivalent of a dramatic play to second the game into overtime. Miraculously, Fajgenbaum survived—only to endure repeated near-death relapses from what would eventually be identified as a form of Castleman disease, an extremely deadly and rare condition that acts like a cross between cancer and an autoimmune disorder. When he relapsed while on the only drug in development and realized that the medical community was unlikely to make progress in time to save his life, Fajgenbaum turned his desperate hope for a cure into concrete action: Between hospitalizations he studied his own charts and tested his own blood samples, looking for clues that could unlock a new treatment. With the help of family, friends, and mentors, he also reached out to other Castleman disease patients and physicians, and eventually came up with an ambitious plan to crowdsource the most promising research questions and recruit world-class researchers to tackle them. Instead of waiting for the scientific stars to align, he would attempt to align them himself. More than five years later and now married to his college sweetheart, Fajgenbaum has seen his hard work pay off: A treatment he identified has induced a tentative remission and his novel approach to collaborative scientific inquiry has become a blueprint for advancing rare disease research. His incredible story demonstrates the potency of hope, and what can happen when the forces of determination, love, family, faith, and serendipity collide. Praise for Chasing My Cure “A page-turning chronicle of living, nearly dying, and discovering what it really means to be invincible in hope.”—Angela Duckworth, #1 New York Times bestselling author of Grit “[A] remarkable memoir . . . Fajgenbaum writes lucidly and movingly . . . Fajgenbaum’s stirring account of his illness will inspire readers.”—Publishers Weekly |
| the laws of medicine siddhartha mukherjee free download: Complications Atul Gawande, 2002 In Gripping Accounts Of True Cases, Atul Gawande Performs Exploratory Surgery On Medicine Itself, Laying Bare A Science Not In Its Idealized Form But As It Actually Is Complicated, Perplexing And Profoundly Human. He Offers An Unflinching View From The Scalpel S Edge, Where Science Is Ambiguous, Information Is Limited, The Stakes Are High, Yet Decisions Must Be Made. Dramatic, Revealing Stories Of Patients And Doctors Explore How Daily Mistakes Occur, Why Good Surgeons Go Bad, And What Happens When Medicine Comes Up Against The Inexplicable: An Architect With Incapacitating Back Pain For Which There Is No Physical Cause; A Young Woman With Nausea That Won T Go Away; A Television Newscaster Whose Blushing Is So Severe That She Cannot Do Her Job. At Once Tough-Minded And Humane, Complications Is A New Kind Of Medical Writing, Nuanced And Lucid, Unafraid To Confront The Uncertainties That Lie At The Heart Of Modern Medicine, Yet Always Alive To The Possibilities Of Wisdom In This Extraordinary Endeavor. Highly Acclaimed Book That Is Destined To Be A Bestseller Literally Straight-From-The-Gut Writing |
| the laws of medicine siddhartha mukherjee free download: Niosh Pocket Guide to Chemical Hazards Niosh, Centers for Disease Control and Preventi, Dhhs, 2012-06-01 The NIOSH Pocket Guide to Chemical Hazards presents information taken from the NIOSH/OSHA Occupational Health Guidelines for Chemical Hazards, from National Institute for Occupational Safety and Health (NIOSH) criteria documents and Current Intelligence Bulletins, and from recognized references in the fields of industrial hygiene, occupational medicine, toxicology, and analytical chemistry. The information is presented in tabular form to provide a quick, convenient source of information on general industrial hygiene practices. The information in the Pocket Guide includes chemical structures or formulas, identification codes, synonyms, exposure limits, chemical and physical properties, incompatibilities and reactivities, measurement methods, respirator selections, signs and symptoms of exposure, and procedures for emergency treatment. |
| the laws of medicine siddhartha mukherjee free download: Clinical Medicine for the MRCP PACES Gautam Mehta, 2010-07-15 A book of 75 cases which mimic the style and approach of the MRCP PACES exam. The book will equip the candidate attempting the MRCP PACES examination, but will also provide an overview of evidence-based medicine for competency-based training. |
| the laws of medicine siddhartha mukherjee free download: Topological Data Analysis for Genomics and Evolution Raul Rabadan, Andrew J. Blumberg, 2019-12-19 An introduction to geometric and topological methods to analyze large scale biological data; includes statistics and genomic applications. |
| the laws of medicine siddhartha mukherjee free download: Malignant S. Lochlann Jain, 2013-10-15 Cancer can kill: this fact makes it concrete. Still, it's a devious knave. Nearly every American will experience it up-close and all too personally, wondering why the billions of research dollars thrown at the word haven't exterminated it from the English language. Like a sapper diffusing a bomb, Jain unscrambles the emotional, bureaucratic, medical, and scientific tropes that create the thing we call cancer. Scientists debate even the most basic facts about the disease, while endlessly generated, disputed, population data produce the appearance of knowledge. Jain takes the vacuum at the center of cancer seriously and demonstrates the need to understand cancer as a set of relationships--economic, sentimental, medical, personal, ethical, institutional, statistical. Malignant analyzes the peculiar authority of the socio-sexual psychopathologies of body parts; the uneven effects of expertise and power; the potentially cancerous consequences of medical procedures such as IVF; the huge industrial investments that manifest themselves as bone-cold testing rooms; the legal mess of medical malpractice law; and the teeth-grittingly jovial efforts to smear makeup and wigs over the whole messy problem of bodies spiraling into pain and decay. Malignant examines the painful cognitive dissonances produced by the ways a culture that has relished dazzling success in every conceivable arena have twisted one of its staunchest failures into an economic triumph. The intractable foil to American achievement, cancer hands us -- on a silver platter and ready for Jain's incisively original dissection -- our sacrifice to the American Dream-- |
| the laws of medicine siddhartha mukherjee free download: Pandemic Exposures Didier Fassin, Marion Fourcade, 2022-06-05 For people and governments around the world, the onset of the COVID-19 pandemic seemed to place the preservation of human life at odds with the pursuit of economic and social life. Yet this simple alternative belies the complexity of the entanglements the crisis has created and revealed, not just between health and wealth but also around morality, knowledge, governance, culture, and everyday subsistence. Didier Fassin and Marion Fourcade have assembled an eminent team of scholars from across the social sciences, conducting research on six continents, to reflect on the multiple ways the coronavirus has entered, reshaped, or exacerbated existing trends and structures in every part of the globe. The contributors show how the disruptions caused by the pandemic have both hastened the rise of new social divisions and hardened old inequalities and dilemmas. An indispensable volume, Pandemic Exposures provides an illuminating analysis of this watershed moment and its possible aftermath. |
| the laws of medicine siddhartha mukherjee free download: The Good Doctor Barron H. Lerner, 2014-05-13 The story of two doctors, a father and son, who practiced in very different times and the evolution of the ethics that profoundly influence health care As a practicing physician and longtime member of his hospital’s ethics committee, Dr. Barron Lerner thought he had heard it all. But in the mid-1990s, his father, an infectious diseases physician, told him a stunning story: he had physically placed his body over an end-stage patient who had stopped breathing, preventing his colleagues from performing cardiopulmonary resuscitation, even though CPR was the ethically and legally accepted thing to do. Over the next few years, the senior Dr. Lerner tried to speed the deaths of his seriously ill mother and mother-in-law to spare them further suffering. These stories angered and alarmed the younger Dr. Lerner—an internist, historian of medicine, and bioethicist—who had rejected physician-based paternalism in favor of informed consent and patient autonomy. The Good Doctor is a fascinating and moving account of how Dr. Lerner came to terms with two very different images of his father: a revered clinician, teacher, and researcher who always put his patients first, but also a physician willing to “play God,” opposing the very revolution in patients' rights that his son was studying and teaching to his own medical students. But the elder Dr. Lerner’s journals, which he had kept for decades, showed the son how the father’s outdated paternalism had grown out of a fierce devotion to patient-centered medicine, which was rapidly disappearing. And they raised questions: Are paternalistic doctors just relics, or should their expertise be used to overrule patients and families that make ill-advised choices? Does the growing use of personalized medicine—in which specific interventions may be best for specific patients—change the calculus between autonomy and paternalism? And how can we best use technologies that were invented to save lives but now too often prolong death? In an era of high-technology medicine, spiraling costs, and health-care reform, these questions could not be more relevant. As his father slowly died of Parkinson’s disease, Barron Lerner faced these questions both personally and professionally. He found himself being pulled into his dad’s medical care, even though he had criticized his father for making medical decisions for his relatives. Did playing God—at least in some situations—actually make sense? Did doctors sometimes “know best”? A timely and compelling story of one family’s engagement with medicine over the last half century, The Good Doctor is an important book for those who treat illness—and those who struggle to overcome it. |
| the laws of medicine siddhartha mukherjee free download: Intimate Matters John D'Emilio, Estelle B. Freedman, 1989 Traces changing American attitudes towards human sexuality, discusses social issues involving race, gender, class, and sexual preference, and looks at crusaders for sexual change |
| the laws of medicine siddhartha mukherjee free download: The Urge Carl Erik Fisher, 2022-01-25 Named a Best Book of the Year by The New Yorker and The Boston Globe An authoritative, illuminating, and deeply humane history of addiction—a phenomenon that remains baffling and deeply misunderstood despite having touched countless lives—by an addiction psychiatrist striving to understand his own family and himself “Carl Erik Fisher’s The Urge is the best-written and most incisive book I’ve read on the history of addiction. In the midst of an overdose crisis that grows worse by the hour and has vexed America for centuries, Fisher has given us the best prescription of all: understanding. He seamlessly blends a gripping historical narrative with memoir that doesn’t self-aggrandize; the result is a full-throated argument against blaming people with substance use disorder. The Urge is a propulsive tour de force that is as healing as it is enjoyable to read.” —Beth Macy, author of Dopesick As a psychiatrist in training fresh from medical school, Carl Erik Fisher found himself face-to-face with an addiction crisis that nearly cost him everything. Desperate to make sense of his condition, he turned to the history of addiction, learning that our society’s current quagmire is only part of a centuries-old struggle to treat addictive behavior. A rich, sweeping account that probes not only medicine and science but also literature, religion, philosophy, and public policy, The Urge introduces us to those who have endeavored to address addiction through the ages and examines the treatments that have produced relief for many people, the author included. Only by reckoning with our history of addiction, Fisher argues, can we light the way forward for those whose lives remain threatened by its hold. The Urge is at once an eye-opening history of ideas, a riveting personal story of addiction and recovery, and a clinician’s urgent call for a more nuanced and compassionate view of one of society’s most intractable challenges. |
| the laws of medicine siddhartha mukherjee free download: Beyond Measure Margaret Heffernan, 2015-05-05 Foundational introduction to the concept that organizations create major impacts by making small changes. |
| the laws of medicine siddhartha mukherjee free download: Morningstar Ann Hood, 2018-08-07 “[An] enchanting journey through Ann Hood’s early fascination with reading.… Book lovers will find Morningstar irresistible.”—Lynn Sharon Schwartz, author of Ruined by Reading Growing up in a mill town in Rhode Island, in a household that didn’t foster a love of reading, novelist Ann Hood discovered nonetheless the transformative power of literature. She learned to channel her imagination, ambitions, and curiosity by devouring ever-growing stacks of books. In Morningstar, Hood recollects with warmth and honesty how The Bell Jar, Marjorie Morningstar, The Harrad Experiment, and The Outsiders influenced her teen psyche and introduced her to topics that could not be discussed at home: desire, fear, sexuality, and madness. Later, Johnny Got His Gun and Grapes of Wrath dramatically influenced her political thinking while the Vietnam War and Kent State shootings became headline news, and classics such as Dr. Zhivago and Les Misérables stoked her ambitions to travel the world. With characteristic insight and charm, Hood showcases the ways in which books gave her life and can transform—even save—our own lives. |
| the laws of medicine siddhartha mukherjee free download: The Courage to Care Christie Watson, 2020-09-17 Nurses have never been more important. 'An inspiring book for our challenging times' Olivia Coleman We benefit from their expertise in our hospitals and beyond: in our schools, on our streets, in prisons, hospices and care homes. When we feel most alone, nurses remind us that we are not alone at all. In The Courage to Care bestselling author Christie Watson reveals the remarkable extent of nurses' work: - A community mental-health nurse choreographs support for a man suffering from severe depression - A teen with stab wounds is treated by the critical-care team; his school nurse visits and he drops the bravado - A pregnant woman loses frightening amounts of blood following a car accident; it is a military nurse who synchronises the emergency department into immaculate order and focus. Christie makes a further discovery: that, time and again, it is patients and their families - including her own - who show exceptional strength in the most challenging times. We are all deserving of compassion, and as we share in each other's suffering, Christie Watson shows us how we can find courage too. The courage to care. 'Let's be thankful for wonderful nurses - and writers - like Christie Watson' Jacqueline Wilson 'The handbook for compassion... a must-read' Chris Evans |
| the laws of medicine siddhartha mukherjee free download: The Book of Why Judea Pearl, Dana Mackenzie, 2018-05-15 The hugely influential book on how the understanding of causality revolutionized science and the world, by the pioneer of artificial intelligence 'Wonderful ... illuminating and fun to read' Daniel Kahneman, Nobel Prize-winner and author of Thinking, Fast and Slow 'Correlation does not imply causation.' For decades, this mantra was invoked by scientists in order to avoid taking positions as to whether one thing caused another, such as smoking and cancer, or carbon dioxide and global warming. But today, that taboo is dead. The causal revolution, sparked by world-renowned computer scientist Judea Pearl and his colleagues, has cut through a century of confusion and placed cause and effect on a firm scientific basis. Now, Pearl and science journalist Dana Mackenzie explain causal thinking to general readers for the first time, showing how it allows us to explore the world that is and the worlds that could have been. It is the essence of human and artificial intelligence. And just as Pearl's discoveries have enabled machines to think better, The Book of Why explains how we too can think better. 'Pearl's accomplishments over the last 30 years have provided the theoretical basis for progress in artificial intelligence and have redefined the term thinking machine' Vint Cerf |
| the laws of medicine siddhartha mukherjee free download: Superbugs Matt McCarthy, 2019-06-04 Drug-resistant bacteria — known as superbugs — are one of the biggest medical threats of our time. Here, a doctor, researcher, and ethics professor tells the exhilarating story of his race to beat them and save countless lives. When doctor Matt McCarthy first meets Jackson, a mechanic from Queens, it is in the ER, where he has come for treatment for an infected gunshot wound. Usually, antibiotics would be prescribed, but Jackson’s infection is one of a growing number of superbugs, bacteria that have built up resistance to known drugs. He only has one option, and if that doesn’t work he may lose his leg or even his life. On the same day, McCarthy and his mentor Tom Walsh begin work on a groundbreaking clinical trial for a new antibiotic they believe will eradicate certain kinds of superbugs and demonstrate to Big Pharma that investment in these drugs can save millions of lives and prove financially viable. But there are countless hoops to jump through before they can begin administering the drug to patients, and for people like Jackson time is in short supply. Superbugs is a compelling tale of medical ingenuity. From the muddy trenches of the First World War, where Alexander Fleming searched for a cure for soldiers with infected wounds, to breakthroughs in antibiotics and antifungals today that could revolutionise how infections are treated, McCarthy takes the reader on a roller-coaster ride through the history — and future — of medicine. Along the way, we meet patients like Remy, a teenage girl with a dangerous and rare infection; Donny, a retired firefighter with a compromised immune system; and Bill, the author’s own father-in-law, who contracts a deadly staph infection. And we learn about the ethics of medical research: why potentially life-saving treatments are often delayed for years to protect patients from exploitation. Can McCarthy get his trial approved and underway in time to save the lives of his countless patients infected with deadly bacteria, who have otherwise lost all hope? |
| the laws of medicine siddhartha mukherjee free download: When Your Child Is Sick Joanna Breyer, 2021-02-18 'Warm, wise and practical' Cressida Cowell, MBE An invaluable reference for parents of sick or hospitalised children by an experienced and eminent psychologist. To many parents, it is hard to imagine a more upsetting reality than one where their child is hospitalised, severely sick, or terminally ill. In When Your Child is Sick, psychologist Joanna Breyer distils decades of experience working with sick children and their families into a comprehensive guide for navigating the uncharted and frightening terrain. She provides expert advice to guide them through the hospital setting, at-home care, and long-term outcomes. Breyer's actionable techniques and direct advice will help parents feel more in-control of a circumstance that has upended their life. She alerts parents to key personnel in the hospital, gives dialogue prompts to help parents ask for the help they need, addresses the needs of their other children at home, offers advice on how to best utilise friends and family who want to help, includes stories from other families who have been there, and teaches coping techniques to help both parents and children weather the stress of prolonged illness and even death. When Your Child is Sick is a valuable guide to managing the myriad practical and emotional complications of an impossible situation. |
| the laws of medicine siddhartha mukherjee free download: Past Life Oracle Cards - a 44-card Deck and Guidebook Dr. Brian L. Weiss, 2014 |
| the laws of medicine siddhartha mukherjee free download: Searching for Peace Ehud Olmert, 2022-03-15 A revealing memoir by the Israeli leader who almost made peace with the Palestinians Written almost entirely from inside a prison cell, Searching for Peace is the compelling memoir of former Israeli prime minister Ehud Olmert. The child of parents who were members of the Irgun, the paramilitary group that fought for the establishment of Israel, Olmert became the youngest member of the Israeli Knesset in 1973, serving in the right-wing Likud party. He rose quickly in the party, serving in national government before being elected mayor of Jerusalem in 1993. As mayor he overcame decades of municipal malaise, inertia, and waves of terror attacks to bring huge improvements in the city's infrastructure, education, and welfare. Although a child of the Israeli right, it was during his mayoralty that he realized the inevitability of compromise and the need to divide the city in any future peace agreement with the Palestinians. Olmert rejoined the national government in 2003 as a top aide to then-Prime Minister Ariel Sharon. After Sharon suffered a debilitating stroke in 2006, Olmert took over as acting prime minister, then led Sharon's new centrist party Kadima to victory in elections. Heading a coalition government, Olmert led Israel through the war with Lebanon in July 2006 and approved the dramatic strike on Syria's nuclear reactor the following year. From late 2006 through 2008, Olmert engaged in some three dozen negotiations with Palestinian leader Mahmoud Abbas. The talks, Olmert says, came “within a hair's breadth” of reaching a comprehensive peace deal. At the same time, Olmert was fighting allegations that he had illegally accepted large sums of money from a well-connected American businessman. He was acquitted of all but a minor charge against him, but in 2014 he was convicted on charges of taking $15,000 in bribes involving the construction of an industrial park while he served as Minister of Industry and Trade. He served 16 months in prison, using his time to write these memoirs. Searching for Peace offers a riveting political story and an unparalleled window into Israeli history, peacemaking, politics, U.S.-Israel relations, and the future of the Middle East. |
| the laws of medicine siddhartha mukherjee free download: David and Goliath Malcolm Gladwell, 2015-04-07 Malcolm Gladwell's provocative new #1 bestseller -- now in paperback. Three thousand years ago on a battlefield in ancient Palestine, a shepherd boy felled a mighty warrior with nothing more than a pebble and a sling-and ever since, the names of David and Goliath have stood for battles between underdogs and giants. David's victory was improbable and miraculous. He shouldn't have won. Or should he? In DAVID AND GOLIATH, Malcolm Gladwell challenges how we think about obstacles and disadvantages, offering a new interpretation of what it means to be discriminated against, suffer from a disability, lose a parent, attend a mediocre school, or endure any number of other apparent setbacks. In the tradition of Gladwell's previous bestsellers-The Tipping Point, Blink, Outliers and What the Dog Saw-DAVID AND GOLIATH draws upon history, psychology and powerful story-telling to reshape the way we think of the world around us. |
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