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| the clinical chemistry of laboratory animals: The Clinical Chemistry of Laboratory Animals David M. Kurtz, Judith S. Prescott, 2017 Preceded by The clinical chemistry of laboratory animals / edited by Walter F. Loeb, Fred W. Quimby. 2nd ed. c1999. |
| the clinical chemistry of laboratory animals: The Clinical Chemistry of Laboratory Animals David M. Kurtz, Gregory S. Travlos, 2017-10-18 Key features: Serves as the detailed, authoritative source of the clinical chemistry of the most commonly used laboratory animals Includes detailed chapters dedicated to descriptions of clinical chemistry-related topics specific to each laboratory species as well as organ/class-specific chapters Presents information regarding evaluation and interpretation of a variety of individual clinical chemistry end points Concludes with detailed chapters dedicated to descriptions of statistical analyses and biomarker development of clinical chemistry-related topics Provides extensive reference lists at the end of each chapter to facilitate further study Extensively updated and expanded since the publication of Walter F. Loeb and Fred W. Quimby’s second edition in 1999, the new The Clinical Chemistry of Laboratory Animals, Third Edition continues as the most comprehensive reference on in vivo animal studies. By organizing the book into species- and organ/class-specific chapters, this book provides information to enable a conceptual understanding of clinical chemistry across laboratory species as well as information on evaluation and interpretation of clinical chemistry data relevant to specific organ systems. Now sponsored by the American College of Laboratory Animal Medicine (ACLAM), this well-respected resource includes chapters on multiple laboratory species and provides pertinent information on their unique physiological characteristics, methods for sample collection, and preanalytical sources of variation for the particular species. Basic methodology for common procedures for each species is also discussed. New Chapters in the Third Edition Include: The Laboratory Zebrafish and Other Fishes Evaluation of Cardiovascular and Pulmonary Function and Injury Evaluation of Skeletal Muscle Function and Injury Evaluation of Bone Function and Injury Vitamins Development of Biomarkers Statistical Methods The Clinical Chemistry of Laboratory Animals, Third Edition is intended as a reference for use by veterinary students, clinical veterinarians, verterinary toxicologists, veterinary clinical pathologists, and laboratory animal veterinarians to aid in study design, collection of samples, and interpretation of clinical chemistry data for laboratory species. |
| the clinical chemistry of laboratory animals: Clinical Chemistry of Laboratory Animals Fred W. Quimby, 1985-05-01 |
| the clinical chemistry of laboratory animals: The Clinical Chemistry of Laboratory Animals WF Loeb (Ed), 1989 |
| the clinical chemistry of laboratory animals: Clinical Chemistry of Laboratory Animals, Second Edition W F Loeb, Fred Quimby, 1999-12-02 This updated and extensively revised edition is designed to aid laboratory animal veterinarians, clinical chemists, toxicologists, clinical pathologists and other biomedical investigators. Clinical Chemistry of Laboratory Animals helps these professionals select and interpret clinical chemistry studies on specimens from laboratory animals. Additionally, this comprehensive reference guides the investigator in the evaluation of organs and systems of laboratory animals. Leading experts contribute knowledge in their respective subspecialties. New chapters that focus on the pig and ferret are included, and toher chapters have been rewritten to incorporate new information. |
| the clinical chemistry of laboratory animals: Manual of Veterinary Clinical Chemistry Leslie C. Sharkey, Judith Radin, 2010-04-15 This title provides veterinary students and non-specialist with a case study base workbook which serves as a guide to effective use and interpretation of clinical chemistry laboratory methods in domestic animals. There are over 100 case studies involving real patients and findings in dogs, cats, horses, lamas, alpacas, pot belled pigs and ferrets. Case studies consist of patient history, physical examination findings, and clinicopthologic data such as CBC, urinalysis, cytology or fluid analysis. A summary is given for each patient that includes a description of follow up tests and response to treatment. Multiple cases of common diseases are included to illustrate the variety of clinciopathologic findings with the same diagnosis depending on individual patient factors. Diagnostic dilemmas in which different diseases may present with similar clinical signs and laboratory data are also included. Published by Teton New Media in the USA and distributed by Manson Publishing outside of North America. |
| the clinical chemistry of laboratory animals: Clinical Biochemistry of Domestic Animals J. J. Kaneko, C. E. Cornelius, 2014-05-10 Clinical Biochemistry of Domestic Animals, Second Edition, Volume I, is a major revision of the first edition prompted by the marked expansion of knowledge in the clinical biochemistry of animals. In keeping with this expansion of knowledge, this edition is comprised of two volumes. Chapters on the pancreas, thyroid, and pituitary-adrenal systems have been separated and entirely rewritten. Completely new chapters on muscle metabolism, iron metabolism, blood clotting, and gastrointestinal function have been added. All the chapters of the first edition have been revised with pertinent new information, and many have been completely rewritten. This volume contains 10 chapters and opens with a discussion of carbohydrate metabolism and associated disorders. Separate chapters follow on lipid metabolism, plasma proteins, and porphyrins. Subsequent chapters deal with liver, pancreatic, and thyroid functions; the role of the pituitary and adrenal glands in health and disease; the function of calcium, inorganic phosphorus, and magnesium metabolism in health and disease; and iron metabolism. |
| the clinical chemistry of laboratory animals: A Toxicologist's Guide to Clinical Pathology in Animals John E. Whalan, 2015-04-09 This guide provides an easy-to-use desk reference for diagnostic information on commonly used hematology, clinical chemistry and urinalysis parameters. Additional reference materials are provided as an aid in evaluating clinical pathology data. For many toxicologists, the evaluation of hematology, clinical chemistry and urinalysis data can be the most challenging aspect of animal toxicity studies. In a typical toxicity study, dozens of parameters are measured several times over the course of the study. There may be hundreds of data points, each of which needs to be considered. A Toxicologist’s Guide to Clinical Pathology in Animals will serve as an essential primer for toxicologists in training and in industry as well as for researchers and professionals in a veterinary practice or a laboratory. |
| the clinical chemistry of laboratory animals: Formulary for Laboratory Animals C. Terrance Hawk, Steven Leary, Timothy Morris, 2005-01-24 Formulary for Laboratory Animals is an invaluable reference for treatment of laboratory animals and pocket pets. Drugs are listed alphabetically and categorized in five sections based on pharmacologic activity and animal species. This at-a-glance pocket reference is valuable for students and practitioners of veterinary medicine, researchers and laboratory technicians who prescribe or administer drugs used on common laboratory animals. The third edition includes a stronger international component, coverage of several new drugs, hundreds of additional dosages, and a thorough update throughout based on the most current research. The third edition also includes a chapter describing how to estimate drug dosages among species using allometric scaling methodology. |
| the clinical chemistry of laboratory animals: The Clinical Chemistry of Laboratory Animals Walter F. Loeb, Fred W. Quimby, 1989 Millions of individual clinical chemistry determinations are performed annual on specimens from rats, mice, and other lab species in the course of biomedi studies. Information obtained is used in a plethora of journal publications agency reports. The objective here is to make this data readily avail. |
| the clinical chemistry of laboratory animals: Animal Clinical Chemistry G.O. Evans, 1996-04-29 By presenting background information on the selection and application of biochemical tests in safety assessment studies, this text seeks to provide a basis for improving the knowledge required to interpret data from toxicological studies. In addition to chapters which discuss the assessment of specific organ toxicity (such as the liver, kidney and thyroid), the book also covers pre-analytical variables, regulatory requirements and statistical approaches, and highlights some of the major differences between man and different laboratory animals. The editor and contributor are all members of the Animal Clinical Chemistry Association, a group formed to advance the science of animal clinical chemistry in safety evaluation, toxicology and veterinary science. |
| the clinical chemistry of laboratory animals: The Laboratory Rat Mark A. Suckow, Steven H. Weisbroth, Craig L. Franklin, 2005-12-20 The Laboratory Rat, Second Edition features updated information on a variety of topics including: rat genetics and genomics, both spontaneous and induced disease; state-of-the-art technology for housing and husbandry; occupational health, and experimental models. A premier source of information on the laboratory rat that will be of interest to veterinary and medical students, senior graduate, graduate students, post-docs and researchers who utilize animals in biomedical research. - At least 50% new information than first edition - Includes topics on rat genetics and genomics, occupational health, and experimental models - The premier source of information on the laboratory rat |
| the clinical chemistry of laboratory animals: Handbook of Laboratory Animal Science, Volume I Jann Hau, Steven J. Schapiro, 2010-12-02 Laboratory animal testing provides most of our current knowledge of human physiology, microbiology, immunology, pharmacology, and pathology. From studies of genetics in fruit flies to studies of cellular processes in genetically modified mice to recent dramatic developments in genetics, translational research, and personalized medicines, biomedical |
| the clinical chemistry of laboratory animals: Equine Hematology, Cytology, and Clinical Chemistry Raquel M. Walton, Rick L. Cowell, Amy C. Valenciano, 2020-11-04 The all-new Equine Hematology, Cytology, and Clinical Chemistry draws on hematology and clinical chemistry information featured in the first edition of Equine Clinical Pathology and adds valuable cytopathology material from Diagnostic Cytology and Hematology of the Horse, making it a truly definitive reference to clinical pathology in equids. Thoroughly updated and expanded throughout, this Second Edition offers more images, more information, and new knowledge for previous chapters and entirely new chapters on bone marrow evaluation and cytopathology. Designed to present clear, concise, and clinically relevant information, the book is logically organized for easy reference. Numerous figures, tables and images support the text, together with summarized information for ease of use. Offers a focus on clinical pathology in the horse, with in-depth information on hematology, clinical chemistry, and cytopathology in equids Presents equine disease from a systems-based, clinicopathological perspective Features hundreds of high-quality images Includes contributions from veterinary specialists with expert knowledge of clinical pathology A must-have purchase for anyone using hematology, clinical chemistry, and cytology in equine patients, Equine Hematology, Cytology, and Clinical Chemistry, 2nd Edition is a valuable resource for equine practitioners, clinical pathologists and residents, and veterinary students. |
| the clinical chemistry of laboratory animals: Education and Training in the Care and Use of Laboratory Animals , |
| the clinical chemistry of laboratory animals: Pathology of Laboratory Rodents and Rabbits Stephen W. Barthold, Stephen M. Griffey, Dean H. Percy, 2016-01-04 Now in its fourth edition, Pathology of Laboratory Rodents and Rabbits has become a standard text for veterinary pathologists, laboratory animal veterinarians, students, and others interested in these species. • The standard reference on the pathogenesis and cardinal diagnostic features of diseases of mice, rats, hamsters, gerbils, guinea pigs, and rabbits • Expanded coverage of rabbit disease, normal anatomic features, and biology • Over 450 color photographs illustrating gross and microscopic pathology • Companion website offering images from the text in PowerPoint |
| the clinical chemistry of laboratory animals: Clinical Pathology and Laboratory Techniques for Veterinary Technicians Amy L. MacNeill, Anne M. Barger, 2024-02-06 Clinical Pathology and Laboratory Techniques for Veterinary Technicians Up-to-date, practical reference book demonstrating laboratory procedures in dogs, cats, cattle and horses The newly revised and updated Second Edition of Clinical Pathology and Laboratory Techniques for Veterinary Technicians is an inclusive reference on laboratory procedures pertaining to small animals, horses, and cattle, providing information on hematology, hemostasis, clinical chemistry, urinalysis, parasitology, endocrine testing, and quality assurance. The text clarifies ‘how-to’ information while also discussing the importance of ‘why’ laboratory procedures are performed in a particular way, enabling readers to gain true understanding of the topics discussed. To aid in reader comprehension, high-quality photographs labeled with magnification and stain information, which clearly depict cellular morphology, inclusions, and infectious organisms, are included throughout each chapter. The text also offers key objectives, technician tip boxes, case examples, and a glossary of key terms, along with a companion website that provides instructor questions, and an answer key to multiple choice questions in the book. Clinical Pathology and Laboratory Techniques for Veterinary Technicians includes information on: Sample collection, handling, and quality assurance, to ensure laboratory test results are valid Hematology data collection techniques that may be used on a daily basis to evaluate the overall health of animal patients Clinical chemistry data to indicate organ function, covering how different chemicals measured in patient samples relate to the function of specific organs in the body In-house parasitology procedures, with important advances in molecular diagnostics have been made that improve the detection and identification of parasites Information about common endocrinopathies and submission of samples for endocrine testing. With complete coverage of the subject, Clinical Pathology and Laboratory Techniques for Veterinary Technicians is an essential resource for students enrolled in veterinary technology programs and veterinary colleges, and may be used as a textbook to guide and supplement information provided in both didactic and laboratory-based clinical pathology courses. |
| the clinical chemistry of laboratory animals: Veterinary Comparative Hematopathology Victor E. Valli, 2008-02-28 Hematopoietic neoplasms are the most common animal tumors for which chemo- or radiation therapy are now given. New research, information, and images unavailable in any previous publication now make it possible to examine these diseases, categorize for treatment, and in some cases ascertain the impact on survival. A ground-breaking book in veterinary medicine, Veterinary Comparative Hematopathology is a heavily illustrated comprehensive reference on hematopoietic neoplasms in domestic and laboratory animals. The book enables veterinary pathologists and oncologists to provide more specificity in both diagnosis and therapy, and will serve as a seminal reference for future work in the field. The book offers a unique comparative approach based on the WHO classification of these tumors in humans. Known animal tumors are described and compared to their counterparts in humans. Those tumors now defined in humans but without a recognized animal counterpart are described in the human context, thus better facilitating future identification in animals. Ground-breaking book in veterinary medicine Over 1400 color images Comprehensive reference for veterinary pathologists and oncologists Unique comparative approach makes this a seminal text on animal tumors |
| the clinical chemistry of laboratory animals: Guide for the Care and Use of Laboratory Animals National Research Council, Division on Earth and Life Studies, Institute for Laboratory Animal Research, Committee for the Update of the Guide for the Care and Use of Laboratory Animals, 2011-01-27 A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates. |
| the clinical chemistry of laboratory animals: The Laboratory Hamster and Gerbil Karl J. Field, Amber L. Sibold, 1998-12-04 The Laboratory Hamster and Gerbil details basic information and common procedures for individuals performing research with hamsters and gerbils. It includes duties of animal facility management, animal husbandry, regulatory compliance, and technical procedures and assists in the humane care and use of hamsters and gerbils in the laboratory. It provides quick, easy-to-use information for investigators, technicians, and animal caretakers and includes references to alternative procedures and methods. The book also offers possible sources and suppliers of animals, feed, sanitation supplies, cages, and research and veterinary supplies. |
| the clinical chemistry of laboratory animals: Temperature Regulation in Laboratory Rodents Christopher J. Gordon, 1993-08-27 With the help of extensive data tables and figures, this book explains the key facets of rodent thermal physiology, including neurological control and gender and intraspecies variations. The book should therefore find use in government, academic or industrial laboratories whose researchers are working with rodents. |
| the clinical chemistry of laboratory animals: Handbook of Laboratory Animal Bacteriology, Second Edition Axel Kornerup Hansen, Dennis Sandris Nielsen, 2014-11-11 The Handbook of Laboratory Animal Bacteriology, Second Edition provides comprehensive information on all bacterial phylae found in laboratory rodents and rabbits to assist managers, veterinary pathologists and laboratory animal veterinarians in the management of these organisms. The book starts by examining the general aspects of bacteriology and how to sample and identify bacteria in animals. It then describes the most relevant species within each phylum and discusses the impact they may have on research. Emphasizing those bacteria known to interfere with research protocols, the book offers methods for isolation and differentiation among related bacteria. It discusses where to purchase reagents for rodent bacteriology and outlines standards for safety in a bacteriological laboratory. Highlights of the second edition: Focuses on modern sequencing techniques based on molecular identification Reorganizes content according to modern systematics based on new identification methods Presents new chapters on mechanisms behind bacterial impact on animal models and on the systematic classification of bacteria Provides information on a range of bacteria interfering with animal models for human disease, not only for those bacteria which cause disease in laboratory animal colonies Includes new figures in color and with enhanced resolution The book is essential reading for those interested in the management of organisms known to interfere with the colony health of rabbits and rodents used in research protocols—including facility managers, clinical veterinarians, veterinary pathologists, and researchers. |
| the clinical chemistry of laboratory animals: Veterinary Hematology and Clinical Chemistry Mary Anna Thrall, 2004 This reference on veterinary haematology and clinical chemistry is designed to be both comprehensive and practical. From basic principles and laboratory techniques to diagnostic evaluation, readers will find equally concise and clear coverage of both haematology and clinical chemistry for many domestic and exotic species. It also features numerous four-colour and black-and-white illustrations, coverage of avian and exotic haematology and an extensive use of case studies. |
| the clinical chemistry of laboratory animals: Laboratory Animal and Exotic Pet Medicine Margi Sirois, 2015-07-24 - NEW! Updated design features more high-quality, full-color illustrations and a revised reader-friendly layout with learning objectives and key points to make content easier to follow. |
| the clinical chemistry of laboratory animals: Hayes' Principles and Methods of Toxicology A. Wallace Hayes, Tetyana Kobets, 2023-07-03 Hayes’ Principles and Methods of Toxicology has long been established as a reliable and informative reference for the concepts, methodologies, and assessments integral to toxicology. The new edition contains updated and new chapters with the addition of new authors while maintaining the same high standards that have made this book a benchmark resource in the field. Key Features: The comprehensive yet concise coverage of various aspects of fundamental and applied toxicology makes this book a valuable resource for educators, students, and professionals. Questions provided at the end of each chapter allow readers to test their knowledge and understanding of the material covered. All chapters have been updated and over 60 new authors have been added to reflect the dynamic nature of toxicological sciences New topics in this edition include Safety Assessment of Cosmetics and Personal Care Products, The Importance of the Dose/Rate Response, Novel Approaches and Alternative Models, Epigenetic Toxicology, and an Expanded Glossary. The volume is divided into 4 major sections, addressing fundamental principles of toxicology (Section I. Principles of Toxicology), major classes of established chemical hazards (Section II. Agents), current methods used for the assessment of various endpoints indicative of chemical toxicity (Section III. Methods), as well as toxicology of specific target systems and organs (Section IV. Organ- and System-Specific Toxicology). This volume will be a valuable tool for the audience that wishes to broaden their understanding of hazards and mechanisms of toxicity and to stay on top of the emerging methods and concepts of the rapidly advancing field of toxicology and risk assessment. |
| the clinical chemistry of laboratory animals: Laboratory Animal Anaesthesia Paul Flecknell, 2009-04-09 Laboratory Animal Anesthesia looks at recent significant developments in anesthetic practices in laboratory experiments involving animals. It also provides information about basic standards for proper use of anesthesia. In addition, it examines the equipment and different anesthetic agents that are used in performing an experiment on animals. The book also discusses the profound effects of anesthesia on the physiological aspect of the animals' body systems, such as hypothermia and respiratory depression. The book addresses the proper management and care that should be provided for the animals that undergo anesthesia. Furthermore, it covers different anesthetic procedures that should be used on various kinds of small animals intended for laboratory experiments. The main goal of this book is to provide information about the different anesthetic agents used in experiments, and the proper standards to follow when using anesthetics on lab animals.• New edition provides new information on anesthesia and analgesia, and has an extensively revised and updated bibliography• Provides a balanced consideration of the needs of scientific research and the welfare of laboratory animals• Written by a veterinary anesthetist and scientist with over 30 years' experience in the field, and who is actively engaged in research in this area• Provides rapid, easily accessed information using tabulated summaries• Provides those with limited experience of anesthesia with the information they need to carry our procedures effectively, safely, and humanely• Provides sufficient depth for the more experienced anesthetist moving to this field |
| the clinical chemistry of laboratory animals: Anesthesia and Analgesia in Laboratory Animals Richard Fish, Peggy J. Danneman, Marilyn Brown, Alicia Karas, 2011-04-28 Anesthesia and Analgesia in Laboratory Animals focuses on the special anesthetic, analgesic, and postoperative care requirements associated with experimental surgery. Fully revised and updated this new edition provides the reader with agents, methods, and techniques for anesthesia and analgesia that ensure humane and successful procedural outcomes. - Provides researchers with the most comprehensive and up-to-date review of the use of anesthesia and analgesia in laboratory animals - Thoroughly updated with new material on ferrets, birds, reptiles, amphibians, fish, and invertebrates - Includes hot topic areas such as pain research, ethical issues, legal issues, and imaging studies |
| the clinical chemistry of laboratory animals: The Mouse in Biomedical Research , 2006-12-15 Normative Biology, Husbandry, and Models, the third volume in the four volume set, The Mouse in Biomedical Research, encompasses 23 chapters whose contents provide a broad overview on the laboratory mouse's normative biology, husbandry, and its use as a model in biomedical research. This consists of chapters on behavior, physiology, reproductive physiology, anatomy, endocrinology, hematology, and clinical chemistry. Other chapters cover management, as well as nutrition, gnotobiotics and disease surveillance. There are also individual chapters describing the mouse as a model for the study of aging, eye research, neurodegenerative diseases, convulsive disorders, diabetes, and cardiovascular and skin diseases. Chapters on imaging techniques and the use of the mouse in assays of biological products are also included. |
| the clinical chemistry of laboratory animals: Exotic Animal Laboratory Diagnosis J. Jill Heatley, Karen E. Russell, 2020-01-27 Exotic Animal Laboratory Diagnosis ist ein praxisorientiertes, leserfreundliches Fachbuch mit allem Wissenswerten für die Durchführung diagnostischer Tests bei vielen Exoten. - Erläutert detailliert, wie Proben entnommen, Tests durchgeführt und Laborergebnisse interpretiert werden. - Bietet Informationen zu jeder Tierart, die zum schnellen Nachschlagen einheitlich präsentiert werden. - Legt den Schwerpunkt auf klinische biochemische Untersuchungen, Urinanalysen und gängige Diagnoseverfahren, die in anderen Publikationen nicht zu finden sind. - Führt in einem leicht zugänglichen Fachbuch alles Wissenswerte zu Auswahl, Durchführung und Anwendung von Testverfahren zusammen. - Deckt eine Vielzahl von Tierarten ab, u. a. Kleinsäugetiere, Primaten, Reptilien, Wassertiere, Wildtiere, Laborversuchstiere und Hausvögel. |
| the clinical chemistry of laboratory animals: The Laboratory Rabbit, Guinea Pig, Hamster, and Other Rodents Mark A. Suckow, Karla A. Stevens, Ronald P. Wilson, 2012-01-09 This is a single volume, comprehensive book sanctioned by the American College of Laboratory Animal Medicine (ACLAM), covering the rabbit, guinea pig, hamster, gerbil and other rodents often used in research. This well illustrated reference includes basic biology, anatomy, physiology, behavior, infectious and noninfectious diseases, husbandry and breeding, common experimental methods, and use of the species as a research model. It is a resource for advancements in the humane and responsible care of: rabbit, guinea pig, hamster, gerbil, chinchilla, deer mouse, kangaroo rat, cotton rat, sand rat, and degu Includes up-to-date, common experimental methods. Organized by species for easy access during bench research. |
| the clinical chemistry of laboratory animals: The Biology of the Laboratory Rabbit Patrick J. Manning, 2014-04-25 After nearly 20 years, the publication of this Second Edition of The Biology of the Laboratory Rabbit attests to its popularity within the scientific community as well as to the need to update an expanding database on the rabbit as a major species in laboratory investigation. The principal aim of this text is to provide a comprehensive and authoritative source of scientifically based information on a major laboratory animal species. The text continues to emphasize the normal biology as well as diseases of the European (domestic) rabbit, Orytolagus cuniculus, especially the New Zealand White breed, with occasional reference to other rabbit species (Sylvilagus sp.) and hares (Lepus sp.). New topics have been added to this second edition in response to changing trends in biomedical research and product testing as well as to suggestions from readers.New chapters included on: - Anesthesia and analgesia - Models in infectious disease research - Models in ophthalmology and vision research - Polyclonal antibody production - Toxicity and safety testing - Drug doses and clinical reference data |
| the clinical chemistry of laboratory animals: Large Animal Internal Medicine - E-Book Bradford P. Smith, 2014-04-01 Large Animal Internal Medicine, 4th Edition features a problem-based approach with discussions of over 150 clinical signs. This is the first internal medicine reference that enables you to efficiently diagnose horses, cattle, sheep, and goats based on clinical observation and laboratory and diagnostic testing. With this user-friendly format, you can find essential information about specific diseases and reach a diagnosis by simply identifying the signs. - A unique problem-based approach with discussions of over 150 clinical signs and manifestations helps you quickly reach a diagnosis based on observations and laboratory tests. - Causes of Presenting Signs boxes provide easy access to complete lists of common, less common, and uncommon diseases associated with manifestations or signs of disease. - Complete lists of diseases associated with a given lab abnormality in Causes of Abnormal Laboratory Values boxes help you easily interpret abnormalities in clinical chemistry, hematology, blood proteins, and clotting tests. - An expert team of over 180 authors contributing information in their areas of expertise ensures you are using the most accurate and up-to-date information available. - Color plates accompanying Diseases of the Eye and Diseases of the Alimentary Tract enable you to visually recognize the clinical appearance of ophthalmologic conditions and alimentary tract disorders for quick and easy diagnosis and treatment. - NEW! Extensively updated content from expert authors clarifies the latest research and clinical findings on pain, the nervous system, toxicology, BVD, malignant catarrhal fever, bluetongue, and strong ions. - NEW! Vaccines and vaccination protocols keep you up-to-date with the information you need to prevent newly emerging diseases in large animals. - NEW! Expanded coverage of the veterinarian's role in animal welfare; equine abdominal ultrasound; DNA, genetic, and PCR testing; and colostrum supplements and replacers supplies you with the most current large animal internal medicine information. - NEW! Current information on foreign animal diseases dangerous to large animals in the US, including coverage of rinderpest, keeps you aware of diseases that can be transmitted from other countries. |
| the clinical chemistry of laboratory animals: Tietz Textbook of Laboratory Medicine - E-Book Nader Rifai, 2022-02-03 Use THE definitive reference for laboratory medicine and clinical pathology! Tietz Textbook of Laboratory Medicine, 7th Edition provides the guidance necessary to select, perform, and evaluate the results of new and established laboratory tests. Comprehensive coverage includes the latest advances in topics such as clinical chemistry, genetic metabolic disorders, molecular diagnostics, hematology and coagulation, clinical microbiology, transfusion medicine, and clinical immunology. From a team of expert contributors led by Nader Rifai, this reference includes access to wide-ranging online resources on Expert Consult — featuring the comprehensive product with fully searchable text, regular content updates, animations, podcasts, over 1300 clinical case studies, lecture series, and more. - Authoritative, current content helps you perform tests in a cost-effective, timely, and efficient manner; provides expertise in managing clinical laboratory needs; and shows how to be responsive to an ever-changing environment. - Current guidelines help you select, perform, and evaluate the results of new and established laboratory tests. - Expert, internationally recognized chapter authors present guidelines representing different practices and points of view. - Analytical criteria focus on the medical usefulness of laboratory procedures. - Use of standard and international units of measure makes this text appropriate for any user, anywhere in the world. - Elsevier eBooks+ provides the entire text as a fully searchable eBook, and includes animations, podcasts, more than 1300 clinical case studies, over 2500 multiple-choice questions, a lecture series, and more, all included with print purchase. - NEW! 19 additional chapters highlight various specialties throughout laboratory medicine. - NEW! Updated, peer-reviewed content provides the most current information possible. - NEW! The largest-ever compilation of clinical cases in laboratory medicine is included with print purchase on Elsevier eBooks+. - NEW! Over 100 adaptive learning courses included with print purchase on Elsevier eBooks+ offer the opportunity for personalized education. |
| the clinical chemistry of laboratory animals: Ferrets, Rabbits and Rodents - E-Book Katherine Quesenberry, Christoph Mans, Connie Orcutt, 2020-04-24 **Selected for Doody's Core Titles® 2024 in Veterinary Medicine**Learn to treat a wide variety of small mammals and pocket pets with Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, 4th Edition. Covering the conditions most often seen in veterinary practice, this highly readable and easy-to-navigate text covers preventative medicine along with disease management, ophthalmology, dentistry, and zoonosis. More than 700 full-color photographs and illustrations highlight radiographic interpretation as well as diagnostic, surgical, and therapeutic techniques. This fourth edition also features new coverage of degus (large rodent species); new coverage of prairie dogs; and expanded coverage of surgical procedures, physical therapy rehabilitation and alternative medicine for rabbits, neoplasia in rabbits, and zoonotic disease. With expert contributors from around the globe, Ferrets, Rabbits, and Rodents is the authoritative, single point of reference for small mammal care that is hard to find elsewhere. - Logical organization lays out sections by different animals and organizes parts within chapters by body system — making it quick and easy to access important information. - Drug formulary provides dosage instructions for a wealth of species including ferrets, rabbits, guinea pigs, chinchillas, hamsters, rats/mice, prairie dogs, hedgehogs, and sugar gliders. - More than 700 photographs and illustrations highlight key concepts such as radiographic interpretation and the main points of diagnostic, surgical, and therapeutic techniques. - Chapter on ophthalmology provides an area of study that is difficult to find for ferrets, rabbits, rodents, and other small mammals. - Chapter outlines offer an at-a-glance overview of the chapter contents at the beginning of the chapter. - Access to Expert Consult site provides an excellent comprehensive reference and a fully searchable eBook. - NEW! Coverage of surgical procedures has been further expanded in this edition. Surgical procedures are presented in a separate section and shown step by step through color photographs and radiographs, accompanied by line drawings. - NEW! Additional information on physical therapy rehabilitation and alternative medicine for rabbits includes chiropractic care and acupuncture. - NEW! Expanded content on neoplasia in rabbits incorporates lymphoreticular disorders, thymoma, and other neoplastic diseases of rabbits. - NEW! All new chapter on prairie dogs has been added. - NEW! All new chapter on degus (large rodent species) has been added. - UPDATED! Chapter on zoonotic disease has been updated to further cover specific zoonotic diseases in addition to addressing the increased potential for disease transmission from animals to humans. - NEW! Global author perspective incorporates the expertise of authors practicing outside of North America. - UPDATED! Photographs show the diseases and disorders that are more commonly seen in practice. |
| the clinical chemistry of laboratory animals: Handbook of Laboratory Health and Safety Measures S.B. Pal, 2013-03-14 During the past two decades, many books, governmental reports and regu lations on safety measures against chemieals, fire, microbiological and radioactive hazards in laboratories have been published from various coun tries. These topics have also been briefly discussed in books on laboratory planning and management. The application ofvarious scientific instruments based on different ionizing and non-ionizing radiations have brought new safety problems to the laboratory workers of today, irrespective of their scientific disciplines, be they medicine, natural or life sciences. However, no comprehensive laboratory handbook dealing with aIl these hazards, some of which are recently introduced, had so far been available in a single volume. Therefore, it was thought worthwhile to publish this Handbook on safety and health measures for laboratories, with contributions from several experts on these subjects. As this second edition of the Handbook, like the first edition, is a multiauthor volume, some duplication in conte nt among chapters is unavoidable in order to maintain the context of a chapter as weIl as make each chapter complete. An attempt has also been made to maintain the central theme, which is how to work in a laboratory with maximum possible environmental safety. |
| the clinical chemistry of laboratory animals: Use of Laboratory Animals in Biomedical and Behavioral Research National Research Council, Institute of Medicine, Institute for Laboratory Animal Research, Commission on Life Sciences, Committee on the Use of Laboratory Animals in Biomedical and Behavioral Research, 1988-02-01 Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action. |
| the clinical chemistry of laboratory animals: Recognition and Alleviation of Pain in Laboratory Animals National Research Council, Division on Earth and Life Studies, Institute for Laboratory Animal Research, Committee on Recognition and Alleviation of Pain in Laboratory Animals, 2009-12-14 The use of animals in research adheres to scientific and ethical principles that promote humane care and practice. Scientific advances in our understanding of animal physiology and behavior often require theories to be revised and standards of practice to be updated to improve laboratory animal welfare. Recognition and Alleviation of Pain in Laboratory Animals, the second of two reports revising the 1992 publication Recognition and Alleviation of Pain and Distress in Laboratory Animals from the Institute for Laboratory Animal Research (ILAR), focuses on pain experienced by animals used in research. This book aims to educate laboratory animal veterinarians; students, researchers and investigators; Institutional Animal Care and Use Committee members; and animal care staff and animal welfare officers on the current scientific and ethical issues associated with pain in laboratory animals. It evaluates pertinent scientific literature to generate practical and pragmatic guidelines for recognizing and alleviating pain in laboratory animals, focusing specifically on the following areas: physiology of pain in commonly used laboratory species; pharmacologic and non-pharmacologic principles to control pain; identification of humane endpoints; and principles for minimizing pain associated with experimental procedures. Finally, the report identifies areas in which further scientific investigation is needed to improve laboratory animal welfare. |
| the clinical chemistry of laboratory animals: Clinical Pathology for the Veterinary Team Andrew J. Rosenfeld, Sharon M. Dial, 2011-11-28 Clinical Pathology for the Veterinary Team is a concise, reliable resource for technical team members performing clinical diagnostic evaluation. Focusing on sample handling, machinery calibration, normal physiology and anatomy, clinical diagnostics, and disease processes, this essential bench-side reference for in-house laboratories helps technical team members to consistently achieve high-quality results in small animal lab work. With chapters on blood counts, chemistry, urinalysis and electrolytes, advanced diagnostics, and cytology, Clinical Pathology for the Veterinary Team offers key technical information for consistently obtaining and evaluating samples. The book is a practical resource for anyone performing lab work, including veterinary technicians, technician and veterinary students, and veterinarians. |
| the clinical chemistry of laboratory animals: Veterinary Hematology William J. Reagan, Armando R. Irizarry Rovira, Dennis B. DeNicola, 2019-05-21 Now in its third edition, Veterinary Hematology: Atlas of Common Domestic and Non-Domestic Species continues to offer veterinarians and veterinary technicians an essential guide to veterinary hematology. Comprehensive in scope, the atlas presents the fundamentals of both normal and abnormal blood cell morphologies, with coverage of a wide range of species, including dogs, cats, horses, ruminants, llamas, rats, mice, nonhuman primates, ferrets, rabbits, guinea pigs, birds, amphibians, and reptiles. Designed as a useful and accessible guide, the updated third edition presents more than 300 color images and includes a new chapter that describes the best techniques for using hematology instruments. The authors—noted experts on the topic—clearly show how to identify and interpret the hematological changes that may occur in a variety of species. In addition, a companion website offers a wealth of additional hematological images. This vital atlas: Provides an updated edition of the popular veterinary hematology atlas for veterinarians, veterinary students, and veterinary technicians Contains a new instructive chapter on hematology instrumentation Presents hundreds of high-quality color photographs that help in identification Covers a range of species from dogs and cats to birds and reptiles Features a companion website that provides a wealth of hematological images Written for both novice and experienced veterinarians, Veterinary Hematology provides a complete resource to blood morphologic abnormalities in domestic and non-domestic species. |
| the clinical chemistry of laboratory animals: Animal Clinical Chemistry G. O. Evans, 1996 By presenting background information on the selection and application of biochemical tests in safety assessment studies, this text seeks to provide a basis for improving the knowledge required to interpret data from toxicological studies. In addition to chapters which discuss the assessment of specific organ toxicity (such as the liver, kidney and thyroid), the book also covers pre-analytical variables, regulatory requirements and statistical approaches, and highlights some of the major differences between man and different laboratory animals. The editor and contributor are all members of the. |
CLINICAL Definition & Meaning - Merriam-Webster
The meaning of CLINICAL is of, relating to, or conducted in or as if in a clinic. How to use clinical in a sentence.
ClinicalTrials.gov
Glossary. Study record managers: refer to the Data Element Definitions if submitting registration or results information.. Search for terms
CLINICAL | English meaning - Cambridge Dictionary
CLINICAL definition: 1. used to refer to medical work or teaching that relates to the examination and treatment of ill…. Learn more.
CLINICAL definition and meaning | Collins English Dictionary
Clinical means involving or relating to the direct medical treatment or testing of patients. [ medicine ] The first clinical trials were expected to begin next year.
Clinical Definition & Meaning | Britannica Dictionary
CLINICAL meaning: 1 : relating to or based on work done with real patients of or relating to the medical treatment that is given to patients in hospitals, clinics, etc.; 2 : requiring treatment as a …
Clinical - definition of clinical by The Free Dictionary
1. pertaining to a clinic. 2. concerned with or based on actual observation and treatment of disease in patients rather than experimentation or theory. 3. dispassionately analytic; …
Clinical Research What is It - Johns Hopkins Medicine
Clinical research is the comprehensive study of the safety and effectiveness of the most promising advances in patient care. Clinical research is different than laboratory research. It involves …
Clinical Research Stages | NIDCR
Click each stage below to access materials and resources related to each phase of clinical research. Learn about how NIDCR works with investigators to ensure that NIDCR-funded …
Meaning of clinical – Learner’s Dictionary - Cambridge Dictionary
CLINICAL definition: 1. relating to medical treatment and tests: 2. only considering facts and not influenced by…. Learn more.
Search Clinical Trials | Find Clinical Trials Near You
ClinicalConnection is your go-to resource for finding clinical trials as a patient, and recruiting patients as a research site. We connect individuals with clinical research trials worldwide. …
CLINICAL Definition & Meaning - Merriam-Webster
The meaning of CLINICAL is of, relating to, or conducted in or as if in a clinic. How to use clinical in a sentence.
ClinicalTrials.gov
Glossary. Study record managers: refer to the Data Element Definitions if submitting registration or results information.. Search for terms
CLINICAL | English meaning - Cambridge Dictionary
CLINICAL definition: 1. used to refer to medical work or teaching that relates to the examination and treatment of ill…. Learn more.
CLINICAL definition and meaning | Collins English Dictionary
Clinical means involving or relating to the direct medical treatment or testing of patients. [ medicine ] The first clinical trials were expected to begin next year.
Clinical Definition & Meaning | Britannica Dictionary
CLINICAL meaning: 1 : relating to or based on work done with real patients of or relating to the medical treatment that is given to patients in hospitals, clinics, etc.; 2 : requiring treatment as a …
Clinical - definition of clinical by The Free Dictionary
1. pertaining to a clinic. 2. concerned with or based on actual observation and treatment of disease in patients rather than experimentation or theory. 3. dispassionately analytic; …
Clinical Research What is It - Johns Hopkins Medicine
Clinical research is the comprehensive study of the safety and effectiveness of the most promising advances in patient care. Clinical research is different than laboratory research. It involves …
Clinical Research Stages | NIDCR
Click each stage below to access materials and resources related to each phase of clinical research. Learn about how NIDCR works with investigators to ensure that NIDCR-funded …
Meaning of clinical – Learner’s Dictionary - Cambridge Dictionary
CLINICAL definition: 1. relating to medical treatment and tests: 2. only considering facts and not influenced by…. Learn more.
Search Clinical Trials | Find Clinical Trials Near You
ClinicalConnection is your go-to resource for finding clinical trials as a patient, and recruiting patients as a research site. We connect individuals with clinical research trials worldwide. …
