Advertisement
| the gene generation torrent: Bioinformatics Dev Bukhsh Singh, Rajesh Kumar Pathak, 2021-10-21 Bioinformatics: Methods and Applications provides a thorough and detailed description of principles, methods, and applications of bioinformatics in different areas of life sciences. It presents a compendium of many important topics of current advanced research and basic principles/approaches easily applicable to diverse research settings. The content encompasses topics such as biological databases, sequence analysis, genome assembly, RNA sequence data analysis, drug design, and structural and functional analysis of proteins. In addition, it discusses computational approaches for vaccine design, systems biology and big data analysis, and machine learning in bioinformatics.It is a valuable source for bioinformaticians, computer biologists, and members of biomedical field who needs to learn bioinformatics approaches to apply to their research and lab activities. - Covers basic and more advanced developments of bioinformatics with a diverse and interdisciplinary approach to fulfill the needs of readers from different backgrounds - Explains in a practical way how to decode complex biological problems using computational approaches and resources - Brings case studies, real-world examples and several protocols to guide the readers with a problem-solving approach |
| the gene generation torrent: Genomic Applications in Pathology George Jabboure Netto, Karen L. Kaul, 2018-12-10 The recent advances in genomics are continuing to reshape our approach to diagnostics, prognostics and therapeutics in oncologic and other disorders. A paradigm shift in pharmacogenomics and in the diagnosis of genetic inherited diseases and infectious diseases is unfolding as the result of implementation of next generation genomic technologies. With rapidly growing knowledge and applications driving this revolution, along with significant technologic and cost changes, genomic approaches are becoming the primary methods in many laboratories and for many diseases. As a result, a plethora of clinical genomic applications have been implemented in diagnostic pathology laboratories, and the applications and demands continue to evolve rapidly. This has created a tremendous need for a comprehensive resource on genomic applications in clinical and anatomic pathology. We believe that our current textbook provides such a resource to practicing molecular pathologists, hematopathologists and other subspecialized pathologists, general pathologists, pathology and other trainees, oncologists, geneticists and a growing spectrum of other clinicians. With periodic updates and a sufficiently rapid time from submission to publication, this textbook will be the resource of choice for many professionals and teaching programs. Its focus on genomics parallels the evolution of these technologies as primary methods in the clinical lab. The rapid evolution of genomics and its applications in medicine necessitates the (frequent) updating of this publication. This text will provide a state-of-the art review of the scientific principles underlying next generation genomic technologies and the required bioinformatics approaches to analyses of the daunting amount of data generated by current and emerging genomic technologies. Implementation roadmaps for various clinical assays such as single gene, gene panels, whole exome and whole genome assays will be discussed together with issues related to reporting and the pathologist’s role in interpretation and clinical integration of genomic tests results. Genomic applications for site-specific solid tumors and hematologic neoplasms will be detailed. Genomic applications in pharmacogenomics, inherited genetic diseases and infectious diseases will also be discussed. The latest iteration of practice recommendations or guidelines in genomic testing put forth by stakeholder professional organizations such as the College of American Pathology and the Association for Molecular Pathology, will be discussed as well as regulatory issues and laboratory accreditation related to genomic testing. All chapters will be written by experts in their fields and will include the most up to date scientific and clinical information. |
| the gene generation torrent: Principles and Practices of OMICS and Genome Editing for Crop Improvement Channa S. Prakash, Sajid Fiaz, Shah Fahad, 2022-07-18 Global food security is increasingly challenging in light of population increase, the impact of climate change on crop production, and limited land available for agricultural expansion. Plant breeding and other agricultural technologies have contributed considerably for food and nutritional security over the last few decades. Genetic engineering approaches are powerful tools that we have at our disposal to overcome substantial obstacles in the way of efficiency and productivity of current agricultural practices. Genome engineering via CRISPR/Cas9, Cpf1, base editing and prime editing, and OMICs through genomics, transcriptomics, proteomics, phenomics, an metabolomics have helped to discover underlying mechanisms controlling traits of economic importance. Principle and Practices of OMICs and Genome Editing for Crop Improvement provides recent research from eminent scholars from around the world, from various geographical regions, with established expertise on genome editing and OMICs technologies. This book offers a wide range of information on OMICs techniques and their applications to develop biotic, abiotic and climate resilient crops, metabolomics and next generation sequencing for sustainable crop production, integration bioinformatics, and multi-omics for precision plant breeding. Other topics include application of genome editing technologies for food and nutritional security, speed breeding, hybrid seed production, resource use efficiency, epigenetic modifications, transgene free breeding, database and bioinformatics for genome editing, and regulations adopted by various countries around globe for genome edited crops. Both OMICs and genome editing are vigorously utilized by researchers for crop improvement programs; however, there is limited literature available in a single source. This book provides a valuable resource not only for students at undergraduate and postgraduate level but also for researchers, stakeholders, policy makers, and practitioners interested in the potential of genome editing and OMICs for crop improvement programs. |
| the gene generation torrent: Microbial Endophytes Ajay Kumar, E.K. Radhakrishnan, 2020-03-05 Microbial Endophytes: Functional Biology and Applications focuses on endophytic bacteria and fungi, including information on foundational endophytes and the latest advances in relevant genomics, proteomics and nanotechnological aspects. The book provides insights into the molecular aspects of plant endophytes and their interactions and applications, also exploring the potential commercialization of endophytic microorganisms and their use as bio fertilizers, in biocontrol, and as bioactive compounds for other sustainable applications. Coverage of important and emerging legal considerations relevant to those working to implement these important bacteria in production processes is also included. - Presents discussion on entry, colonization and the distribution of endophytic microorganisms - Explores the phyto immunological functions of endophytic microorganisms - Provides genomic insights on plant endophyte interaction - Identifies bio-commercial aspects of microbial endophytes for sustainable agriculture, including potential legal issues and IPR in microbial research |
| the gene generation torrent: "Source-tracking”, molecular epidemiology and antigenic diversity of SARS-CoV-2 infections causing coronavirus disease 2019, COVID-19 Charles A. Narh, Cordelia Manickam, Davide Zella, Lydia Mosi, Bathri Narayan Vajravelu, 2022-11-16 |
| the gene generation torrent: Genomes 4 T. A. Brown, 2018-12-07 Genomes 4 has been completely revised and updated. It is a thoroughly modern textbook about genomes and how they are investigated. As with Genomes 3, techniques come first, then genome anatomies, followed by genome function, and finally genome evolution. The genomes of all types of organism are covered: viruses, bacteria, fungi, plants, and animals including humans and other hominids. Genome sequencing and assembly methods have been thoroughly revised including a survey of four genome projects: human, Neanderthal, giant panda, and barley. Coverage of genome annotation emphasizes genome-wide RNA mapping, with CRISPR-Cas 9 and GWAS methods of determining gene function covered. The knowledge gained from these techniques forms the basis of the three chapters that describe the three main types of genomes: eukaryotic, prokaryotic (including eukaryotic organelles), and viral (including mobile genetic elements). Coverage of genome expression and replication is truly genomic, concentrating on the genome-wide implications of DNA packaging, epigenome modifications, DNA-binding proteins, non-coding RNAs, regulatory genome sequences, and protein-protein interactions. Also included are applications of transcriptome analysis, metabolomics, and systems biology. The final chapter is on genome evolution, focusing on the evolution of the epigenome, using genomics to study human evolution, and using population genomics to advance plant breeding. Established methods of molecular biology are included if they are still relevant today and there is always an explanation as to why the method is still important. Each chapter has a set of short-answer questions, in-depth problems, and annotated further reading. There is also an extensive glossary. Genomes 4 is the ideal text for upper level courses focused on genomes and genomics. |
| the gene generation torrent: Bioinformatics for Beginners Supratim Choudhuri, 2014-05-09 Bioinformatics for Beginners: Genes, Genomes, Molecular Evolution, Databases and Analytical Tools provides a coherent and friendly treatment of bioinformatics for any student or scientist within biology who has not routinely performed bioinformatic analysis. The book discusses the relevant principles needed to understand the theoretical underpinnings of bioinformatic analysis and demonstrates, with examples, targeted analysis using freely available web-based software and publicly available databases. Eschewing non-essential information, the work focuses on principles and hands-on analysis, also pointing to further study options. - Avoids non-essential coverage, yet fully describes the field for beginners - Explains the molecular basis of evolution to place bioinformatic analysis in biological context - Provides useful links to the vast resource of publicly available bioinformatic databases and analysis tools - Contains over 100 figures that aid in concept discovery and illustration |
| the gene generation torrent: Molecular Diversity of Environmental Prokaryotes Thiago Bruce Rodrigues, Amaro Emiliano Trindade Silva, 2016-08-19 This book correlates the vast genetic diversity associated with environmental samples and still underexploited potential for the development of biotechnology products. The book points out the potential of different types of environmental samples. It presents the main characteristics of microbial diversity, the main approaches used for molecular characterization of the diversity, and practical examples of application of the exploration of the microbial diversity. It presents a not-yet-explored structure for discussing the main topics related to molecular biology of environmental prokaryotes and their biotechnological applications. |
| the gene generation torrent: Nucleosomes, Histones and Chromatin Part B , 2012-12-31 This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. The volume covers nucleosomes, histones and chromatin and has chapters on dynamic mapping of histone-DNA interactions in nucleosomes by unzipping single molecules of DNA, digital DNase technology, and genome-wide analysis of chromatin transition. - Contains quality chapters authored by leaders in the field - The volume covers nucleosomes, histones and chromatin - Has chapters on dynamic mapping of histone-DNA interactions in nucleosomes by unzipping single molecules of DNA, digital DNase technology, and genome-wide analysis of chromatin transition |
| the gene generation torrent: Achieving Nutritional Security and Food Safety Through Genomics-Based Breeding of Crops Reyazul Rouf Mir, Sachiko Narita Isobe, Manish Kumar Pandey, Ajay Kumar, 2021-03-22 |
| the gene generation torrent: Clinical Genomics Shashikant Kulkarni, Somak Roy, 2014-11-10 Clinical Genomics provides an overview of the various next-generation sequencing (NGS) technologies that are currently used in clinical diagnostic laboratories. It presents key bioinformatic challenges and the solutions that must be addressed by clinical genomicists and genomic pathologists, such as specific pipelines for identification of the full range of variants that are clinically important. This book is also focused on the challenges of diagnostic interpretation of NGS results in a clinical setting. Its final sections are devoted to the emerging regulatory issues that will govern clinical use of NGS, and reimbursement paradigms that will affect the way in which laboratory professionals get paid for the testing. - Simplifies complexities of NGS technologies for rapid education of clinical genomicists and genomic pathologists towards genomic medicine paradigm - Tried and tested practice-based analysis for precision diagnosis and treatment plans - Specific pipelines and meta-analysis for full range of clinically important variants |
| the gene generation torrent: Nucleosomes, Histones & Chromatin Carl Wu, C. David Allis, 2012 Covers nucleosomes, histones and chromatin, with chapters on dynamic mapping of histone-DNA interactions in nucleosomes by unzipping single molecules of DNA, Digital DNase technology, and Genome-wide Analysis of Chromatin Transition. |
| the gene generation torrent: The Gut Microbiome Vivian C. H. Wu, 2022-12-16 The influence of the gut microbiome on human health and disease has been established in recent years through advances in high-throughput DNA sequencing. The Gut Microbiome: Bench to Table presents a scientific introduction to this topic, analyzes research on how the microbiome is affected by nutrients, and how dietary modifications can alter the microbiome. Written by a multidisciplinary team of experts it is divided into three sections. The first section details the current state of laboratory-scale analysis of gut microbiome samples and how we can identify the communities and their functional repertoire. Section II explains the next phase of translational research models such as preclinical, animal studies, proof of concept safety, and efficacy human trials. The third section demonstrates the effectiveness of therapeutic treatments in larger populations. It addresses how diet influences the gut microbiome and presents an array of approaches that have been reported, including a discussion of issues of the safety of probiotics and selected supplements and micronutrients. This book is essential for clinicians, dietitians and food and nutrition professionals who wish to have the most up-to-date knowledge on food sciences. |
| the gene generation torrent: CELLULAR AND MOLECULAR PHARMACOLOGY Ms. Manisha Chhikara , Dr Tanuj Hooda, Dr Amit Lather, Mrs Pooja Suridia , Mrs. Chetna Verma , Mrs. Jyoti Dahiya , ..... |
| the gene generation torrent: Genomic, Proteomics, and Biotechnology RC Sobti, Manishi Mukesh, Aastha Sobti, 2022-12-29 High-throughput molecular technologies (omics) can help to decipher the contributions of different physiological systems and identify candidate molecules that are representative of different physiological pathways thereby allowing the discovery of biomarkers. Notably, the omics technologies along with and computational methods, bioprospecting, and artificial intelligence will continue to lead to better understanding of biological mechanisms that are responsible for physical attributes, or phenotypes. Research breakthroughs obtained through these technologies can be used to enhance productivity of food animals, meet the increasing demand for animal-sourced foods, enhance high-quality nutrient availability, ensure nutrient safety, mitigate the effects of climate variability, and result in new technologies that provide continued improvement in food security worldwide. Such breakthroughs are an urgent necessity because over the past 50 years, there has been an unprecedented increase in the world’s population, which will reach ten billion by the year 2050. Innovative and technological advancements that enhance all aspects of food production will arise from basic, fundamental research. Besides food, animal by-products have found many applications in the fields of pharmaceuticals, cosmetics, and household and industrial products. Hence, the need to ameliorate the productivity, reproductivity, growth performance, and disease resistance in animals has created a worldwide interest in gaining a deeper understanding of animal biology, biotechnology and genomics, and proteomics. The present volume thoroughly discusses the omics studies in domestic and non-domestic animals and their role in mitigation of various challenges ahead. The volume thus focuses on i. Omics (genomics, proteomics, transcriptomics, metabolonomics) technologies in identifying, characterizing biodiversity ii. Role of molecular techniques for improvement of domestic and non-domestic organisms iii. Animal and alternative model systems (using stem cells, tissue engineering, cell free systems, 3D platforms etc.) for studying life phenomena iv. Genetically modified organisms as factories for the products |
| the gene generation torrent: Henry's Clinical Diagnosis and Management by Laboratory Methods E-Book Richard A. McPherson, Matthew R. Pincus, 2021-06-09 For more than 100 years, Henry's Clinical Diagnosis and Management by Laboratory Methods has been recognized as the premier text in clinical laboratory medicine, widely used by both clinical pathologists and laboratory technicians. Leading experts in each testing discipline clearly explain procedures and how they are used both to formulate clinical diagnoses and to plan patient medical care and long-term management. Employing a multidisciplinary approach, it provides cutting-edge coverage of automation, informatics, molecular diagnostics, proteomics, laboratory management, and quality control, emphasizing new testing methodologies throughout. - Remains the most comprehensive and authoritative text on every aspect of the clinical laboratory and the scientific foundation and clinical application of today's complete range of laboratory tests. - Updates include current hot topics and advances in clinical laboratory practices, including new and extended applications to diagnosis and management. New content covers next generation mass spectroscopy (MS), coagulation testing, next generation sequencing (NGS), transfusion medicine, genetics and cell-free DNA, therapeutic antibodies targeted to tumors, and new regulations such as ICD-10 coding for billing and reimbursement. - Emphasizes the clinical interpretation of laboratory data to assist the clinician in patient management. - Organizes chapters by organ system for quick access, and highlights information with full-color illustrations, tables, and diagrams. - Provides guidance on error detection, correction, and prevention, as well as cost-effective test selection. - Includes a chapter on Toxicology and Therapeutic Drug Monitoring that discusses the necessity of testing for therapeutic drugs that are more frequently being abused by users. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices. |
| the gene generation torrent: Sequencing Technologies in Microbial Food Safety and Quality Devarajan Thangardurai, Leo M.L. Nollet, Saher Islam, Jeyabalan Sangeetha, 2021-04-14 Molecular landscape for food safety analysis is rapidly revolutionizing because of high resolution and value added resulting analysis of next-generation sequencing (NGS) approaches. These modern sequencing technologies drive worldwide advancements in food safety and quality. Sequencing Technologies in Microbial Food Safety and Quality reviews several practices in that NGS contributes to foodborne pathogens functional characterization, management and control. This book focuses on potential uses of sequencing technologies in microbial food safety and quality and highlights present challenges in the food industry. Key Features: Application of whole genome sequencing technologies in disease diagnostics, surveillance, transmission, and outbreak investigation in food sector Impact of sequencing tools in the area of food microbiology Recent advances in genomic DNA sequencing of microbial species from single cells Microbial bioinformatics resources for food microbiology High-throughput insertion tracking by deep sequencing for the analysis of food pathogens This book includes contributions from experts who have manipulated sequencing tools in relation to microbial food safety and quality. Presenting comprehensive details about NGS approaches in food science, this book is an updated and reliable reference for food scientists, nutritionists, food product investigators to study and implement the sequencing technologies for developing quality and safe food. This book would also serve as informative resource for food industry officials, government researchers, food science or food nutrition students who seek comprehensive knowledge about the role of emerging sequencing technologies in revolutionizing the food industry. |
| the gene generation torrent: Companion and Complementary Diagnostics Jan Trøst Jørgensen, 2019-05-08 Companion and Complementary Diagnostics: From Biomarker Discovery to Clinical Implementation provides readers with in-depth insights into the individual steps in the development of companion diagnostic assays, from the early biomarker discovery phase straight through to final regulatory approval. Further, the clinical implementation of companion diagnostic testing in the clinic is also discussed. As the development of predictive or selective biomarker assays linked to specific drugs is substantially increasing, this book offers comprehensive information on this quickly-evolving area of biomedicine. It is an essential resource for those in academic institutions, hospitals and pharma, and biotech and diagnostic commercial companies. - Covers all aspects, from biomarker discovery, to development and regulatory approval - Explains the how to aspects of companion diagnostics - Incorporates information on the entire process, allowing for easier and deeper understanding of the topic |
| the gene generation torrent: Genome-Wide Association Studies Krishnarao Appasani, 2016-01-14 Over the last twenty years, genome-wide association studies (GWAS) have revealed a great deal about the genetic basis of a wide range of complex diseases and they will undoubtedly continue to have a broad impact as we move to an era of personalised medicine. This authoritative text, written by leaders and innovators from both academia and industry, covers the basic science as well as the clinical, biotechnological and pharmaceutical potential of these methods. With special emphasis given to highlighting pharmacogenomics and population genomics studies using next-generation technology approaches, this is the first book devoted to combining association studies with single nucleotide polymorphisms, copy number variants, haplotypes and expressed quantitative trait loci. A reliable guide for newcomers to the field as well as for experienced scientists, this is a unique resource for anyone interested in how the revolutionary power of genomics can be applied to solve problems in complex disease. |
| the gene generation torrent: Sabiston and Spencer Surgery of the Chest, E-Book Frank W. Sellke, Pedro J. del Nido, Scott J. Swanson, 2023-09-27 **Selected for Doody's Core Titles® 2024 in Thoracic Surgery**The only text to cover the full range of adult cardiac, thoracic, and pediatric chest surgery, Sabiston and Spencer Surgery of the Chest, 10th edition provides unparalleled guidance in a single, two-volume resource. This gold standard reference, edited by Drs. Frank Sellke, Pedro del Nido, and Scott Swanson, covers today's most important knowledge and techniques in cardiac and thoracic surgery—the information you need for specialty board review and for day-to-day surgical practice. Meticulously organized so that you can quickly find expert information on open and endoscopic surgical techniques, this 10th Edition is an essential resource not only for all cardiothoracic surgeons, but also for physicians, residents, and students concerned with diseases of the chest. - Features short, focused chapters divided into three major sections: Adult Cardiac Surgery, Pediatric Cardiac Surgery, and Thoracic Surgery - Presents the knowledge and expertise of global experts who provide a comprehensive view of the entire specialty - Provides full-color coverage throughout, helping you visualize challenging surgical techniques and procedures and navigate the text efficiently - Includes new chapters on dissection complications and percutaneous treatment of mitral and tricuspid valve disease - Offers extensively revised or rewritten chapters on surgical revascularization, acute dissection, vascular physiology, the latest innovations in minimally invasive cardiothoracic surgery and percutaneous devices, the molecular biology of thoracic malignancy, robotics in chest surgery, congenital valve reconstructions, novel hybrid procedures in pediatric cardiac surgery, and 3D visualization of cardiac anatomy for surgical procedure planning - Keeps you up to date with the latest developments in cardiothoracic imaging and diagnosis - Provides access to more than 30 surgical videos online, and features new figures, tables, and illustrations throughout |
| the gene generation torrent: Biochips and Medical Imaging Adam de la Zerda, Shan Xiang Wang, 2022-07-19 Advanced, recent developments in biochips and medical imaging Biochips and Medical Imaging is designed as a professional resource, covering recent biochip and medical imaging developments. Within the text, the authors encourage uniting aspects of engineering, biology, and medicine to facilitate advancements in the field of molecular diagnostics and imaging. Biochips are microchips for efficiently screening biological analytes. This book aims at presenting information on the state-of-the-art and emerging biosensors, biochips, and imaging devices of the body's systems, including the endocrine, circulatory, and immune systems. Medical diagnostics includes biochips (in-vitro diagnostics) and medical and molecular imaging (in-vivo imaging). Biochips and Medical Imaging explores the role of in-vitro and in-vivo diagnostics. It enables an instructor to share in-depth examples of the use of biochips in diagnosing cancer and cardiovascular diseases. Provides real-life knowledge on biochips and medical imaging, written by leading researchers Serves as a resource for professionals working in the biochip or imaging fields Features an accessible approach for anyone interested in biochips and their applications Readers of Biochips and Medical Imaging can expand their knowledge of medical technology, even if they have no biological knowledge and a limited math background. With its focus on important developments, this book is sure to also capture the interest of bioengineering and biomaterials scientists, structural biologists, electrical engineers, and nanotechnologists. |
| the gene generation torrent: Network World , 1998-01-19 For more than 20 years, Network World has been the premier provider of information, intelligence and insight for network and IT executives responsible for the digital nervous systems of large organizations. Readers are responsible for designing, implementing and managing the voice, data and video systems their companies use to support everything from business critical applications to employee collaboration and electronic commerce. |
| the gene generation torrent: Plant Pathology Nicola Luchi, 2022-07-12 This volume covers the latest developments in different areas of plant pathology. The chapters in this volume are organized into seven parts. Part One provides traditional methods for isolation and identification of invasive pathogens and root disease. Part Two looks at new and rapid DNA extraction protocols from different samples, and Part Three focuses on molecular detection protocols for identifying and quantifying plant pathogens, including fungal and bacterial invasive species. Part Four describes the application of metabarcoding in plant pathology, and Part Five talks about plant pathogen interactions. Part Six concentrates on population genomics of plant pathogens, and Part Seven covers biocontrol on plant pathogens. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Plant Pathology: Methods and Protocols is a valuable resource for researchers in the plant pathology community, and discusses various approaches for the detection, identification, and control of plant diseases. |
| the gene generation torrent: Basic and Advanced Laboratory Techniques in Histopathology and Cytology Pranab Dey, 2023-01-01 The second edition of this well-received book provides detailed information on the basic and advanced laboratory techniques in histopathology and cytology. It offers clear guidance on the principles and techniques of routine and special laboratory techniques. It also covers advanced laboratory techniques such as immunocytochemistry, flow cytometry, liquid-based cytology, polymerase chain reactions, tissue microarray, molecular technology, etc. The book's second edition covers several important recent topics with many new chapters, such as liquid biopsy, artificial neural network, digital pathology, and next-generation sequencing. Each chapter elucidates basic principle, practical methods, troubleshooting, and clinical applications of the technique. It includes multiple colored line drawings, microphotographs, and tables to illustrate each technique. The book is a helpful guide to the post-graduate students and fellows in pathology, practicing pathologists, as well as laboratory technicians, and research students. |
| the gene generation torrent: Development in Waste Water Treatment Research and Processes Maulin P. Shah, Nidhi Shah, 2024-06-19 Development in Waste Water Treatment Research and Processes: Role of Environmental Microbiology in Industrial Wastewater Research focuses on environmental bioremediation concepts, providing a comprehensive view of recent trends and emerging technologies in environmental bioremediation, addressing current limitations and challenges pertaining to generally accepted and applied bioremediation strategies, and discussing corrective strategies for the removal of pollutants from the environment.Describing the broader role of environmental microbiology specifically in the treatment of industrial wastewater research, the book includes sections on the recovery of resources from wastewater that will be of interest to environmental microbiologists, biotechnologists, environmental engineers, chemical engineers, and those working in the bioremediation field. - Describes the importance of microorganisms in environmental bioremediation technologies - Points out the reuse of treated wastewater through emerging technologies - Pays special attention to the occurrence of novel micro-pollutants |
| the gene generation torrent: Translational Cardiometabolic Genomic Medicine Annabelle Rodriguez-Oquendo, 2015-09-07 Translational Cardiometabolic Genomic Medicine, edited by Dr. Annabelle Rodriguez-Oquendo, is an important resource to postgraduate (medical, dental and graduate) students, postdoctoral fellows, basic scientists, and physician scientists seeking to understand and expand their knowledge base in the field of genomic medicine as it is applied to cardiometabolic diseases. This handbook integrates cutting-edge experimental approaches such as chromatin immunoprecipitation paired end tagging (CHIA-PET), to population studies such as the Multi-Ethnic Study of Atherosclerosis. It encompasses a range of book chapters that highlight bioinformatic approaches to better understanding functionality of the noncoding regions of the human genome to the use of molecular diagnostic testing in predicting increased risk of cardiovascular diseases. Where applicable, this reference also includes chapters related to therapeutic options specifically aligned to molecular targets. - Provides comprehensive research on translational genomic medicine - Explains state-of-the-art genome editing for stem cells and mouse models with significant relevance to human cardiometabolic disease - Includes discussions on the functional effects of single nucleotide polymorphisms and cardiometabolic diseases, stratified by sex and race - Encompasses a range of book chapters that highlight bioinformatic approaches to better understanding functionality of the noncoding regions of the human genome |
| the gene generation torrent: Broadening the Genetic Base of Grain Cereals Mohar Singh, Sandeep Kumar, 2016-09-13 This book offers comprehensive coverage of important grain cereals including their origin and distribution, crop gene pool, level of diversity, production constraints, traits of importance for genetic base widening, crop improvement methodologies, genome mapping, genomics for breeding, and future strategies. The chapters, contributed by eminent crop researchers from around the world, provide rare insights into the crop-specific constraints and prospects drawing from their substantial experience. As such, the book offers an essential source of information for grain cereals scientists, teachers, students, policy planners and developmental experts alike. Grain cereals, which comprise rice, wheat, maize, barley, oats, sorghum and millets, are members of the grass family. These crops are vital to human nutrition, thanks to their roles as staple food crops in different parts of the globe. Some of them are rich sources of carbohydrates, which provide energy, while others are important sources of minerals, vitamins and proteins, in addition to their medicinal properties. In most cereals, the existing variability among elite germplasm has been exploited to attain a desirable level of productivity. However, to make further breakthroughs in enhancing yield and improving stability in future crop cultivars, new sources of genes/alleles need to be identified in wild/weedy species and incorporated into the cultivated varieties. Though there have been many publications on various aspects of grain cereal improvement in the recent past, to date this essential information has remained scattered among different periodicals. |
| the gene generation torrent: Bioinformatics and Biomedical Engineering Ignacio Rojas, Olga Valenzuela, Fernando Rojas Ruiz, Luis Javier Herrera, Francisco Ortuño, 2023-06-28 This volume constitutes the proceedings of the 10th International Work-Conference on IWBBIO 2023, held in Meloneras, Gran Canaria, Spain, during July 12-14, 2022. The total of 79 papers presented in the proceedings, was carefully reviewed and selected from 209 submissions. The papers cove the latest ideas and realizations in the foundations, theory, models, and applications for interdisciplinary and multidisciplinary research encompassing disciplines of computer science, mathematics, statistics, biology, bioinformatics, and biomedicine. |
| the gene generation torrent: Carrion Ecology, Evolution, and Their Applications M. Eric Benbow, Jeffery K. Tomberlin, Aaron M. Tarone, 2015-08-18 Shortlisted for the 2018 TWS Wildlife Publication Awards in the edited book categoryDecomposition and recycling of vertebrate remains have been understudied, hampered largely due to these processes being aesthetically challenging (e.g., smell and sight). Technological innovations have provided the means to explore new and historically understo |
| the gene generation torrent: Automation and Emerging Technology in Clinical Microbiology, An Issue of Clinics in Laboratory Medicine Carey-Ann D. Burnham, 2013-09-28 The field of Clinical Microbiology is evolving at a rapid pace, perhaps more so than any other arm of laboratory medicine. This can be attributed to new technology, including high throughput gene sequencing, multiplex molecular assays, rapid evolution of antimicrobial resistance, and discovery of new pathogens. In addition, modern medical procedures, such as solid organ and stem cell transplantation, have resulted in an explosion of infections with agents that historically have been considered to be of low virulence. This issue of Clinics in Laboratory Medicine will highlight some of the advances in diagnostic microbiology, including MALDI-TOF MS, pathogen discovery, and personalized antimicrobial chemotherapy. In addition, one of the papers will focus on implementation of new technologies and how to maximize patient impact of these new methods. |
| the gene generation torrent: Clinical Molecular Diagnostics Shiyang Pan, Jinhai Tang, 2021-07-08 This book covers the discovery of molecular biomarkers, the development of laboratory testing techniques and their clinical applications, focusing on basic research to clinical practice. It introduces new and crucial knowledge and ethics of clinical molecular diagnosis. This book emphasizes the applications of clinical molecular diagnostic test on health management, especially from different diseased organs. It lets readers to understand and realize precision healthcare. |
| the gene generation torrent: The Crisis: a Discourse of the Aspects of Providence, in November 1777; by James Morison .. James Morison (of Norham.), 1778 |
| the gene generation torrent: Genetic testing in pediatric disorders Merlin G. Butler, Jessica Duis, 2024-01-03 |
| the gene generation torrent: Forensic DNA Analysis Elena Pilli, Andrea Berti, 2021-03-31 Forensic DNA Analysis: Technological Development and Innovative Applications provides a fascinating overview of new and innovative technologies and current applications in forensic genetics. Edited by two forensic experts with many years of forensic crime experience with the Italian police and with prestigious academic universities, the volume takes an interdisciplinary perspective, the volume presents an introduction to genome polymorphisms, discusses, forensic genetic markers, presents a variety of new methods and techniques in forensic genetics, and looks at a selection of new technological innovations and inventions now available from commercial vendors. The book is an important resource for scientists, researchers, and other experts in the field who will find it of interest for its exhaustive discussion of the most important technological innovations in forensic genetics. For those newer to the field, the volume will be an invaluable reference guide to the forensic world. |
| the gene generation torrent: Oncogenomics Franco Dammacco, Franco Silvestris, 2018-10-30 Oncogenomics: From Basic Research to Precision Medicine offers a thorough survey of precision medicine and its diagnostic and therapeutic applications in oncology. Gathering contributions from leading international researchers in the field, chapters examine recent translational advances in oncogenomic methods and technologies, detailing novel molecular classifications of tumors as well as diagnostic and prognostic biomarkers for various types of cancers including pancreatic, gastrointestinal, breast, hematological, lung, osteotropic, genitourinary, and skin cancers. This book provides a foundation for clinical oncologists, human geneticists, and physicians to develop new targeted cancer treatments and incorporate genomic medicine into clinical practice, with particular attention paid to noninvasive diagnostic techniques such as the liquid biopsy and molecular characterization of solid malignancies. - Provides clinical oncologists, human geneticists, physicians, and students with a thorough understanding of current diagnostic and prognostic applications of genomic methods and technologies to a variety of solid malignancies - Employs current knowledge in oncogenomics towards developing therapeutic interventions for various cancer types - Features a team of internationally recognized researchers and physicians in clinical oncology, oncogenomics and precision medicine |
| the gene generation torrent: The Role of Immune Checkpoint Molecules in Solid and Hematopoietic Stem Cell Transplantation Vera Rebmann, Lambros Kordelas, Frans H. J. Claas, 2022-02-07 |
| the gene generation torrent: Toxicogenomics in non-mammalian species Stephen Sturzenbaum, Michael Aschner, Jonathan Freedman, Some molecules or conditions are exclusively toxic to biological systems and classified as being non-essential; others are essential for life. Nevertheless, above certain threshold even the essential will become toxic. Tightly controlled homeostatic control mechanisms are thus vital drivers of well being, longevity and survival. The identification and characterization of these intricate pathways form the foundations of Toxicogenomics. The initiation, and indeed completion, of numerous non-mammalian genome-sequencing projects, has driven the exponential growth of available genetic sequences. Collating this vast amount of data into functional and mechanistically meaningful units will provide novel insights into pathogenesis, new methods of risk assessment, genetic risk-modifications in preventative medicine and new therapeutic targets for pharmaceutical and biological medicines. This Research Topic issue will explore the current knowledgebase pertaining to the multitude of genomic and toxicological tools within non-mammalian organisms. The encyclopaedic coverage will span the full taxonomic breadth ranging from simple unicellular bacteria and yeast to complex creatures such as birds and fish. The resulting collection of unique, complimentary or indeed contrasting approaches, tools and technologies (which are defined by the availability and feasibility for each organism to study genomics of xenobiotic or stress biology) will not only foster cross-phyla awareness but expand the horizon of Toxicogenomics. |
| the gene generation torrent: Metagenomics: Techniques, Applications, Challenges and Opportunities Reena Singh Chopra, Chirag Chopra, Neeta Raj Sharma, 2020-09-08 This book summarizes the various areas of research in metagenomics and their potential applications in medicine, the environment and biotechnology. The book presents the recent advances in theoretical, methodological and applied aspects of metagenomics and highlights their applications in the fields of environmental microbial forensics, bioremediation, drug-discovery and agriculture. In addition, the book discusses various metagenomics approaches used for understanding the microbial physiology and biochemistry. Lastly the book describes a range of bioinformatics tools and computational methods for metagenomics analysis as well as the functional diversity and dynamics of microbial communities colonizing the human skin. |
| the gene generation torrent: Modern Techniques in Biosensors Gorachand Dutta, Arindam Biswas, Amlan Chakrabarti, 2021-01-04 This book focusses on recent advances and different research issues in the biosensor technology and also presents theoretical, methodological, well-established and validated empirical work dealing with the technology. The book addresses challenges for the development of a point-of-care test platform. The book also describes printed chip-based assay (Lab-on-a-Chip, Lab-on-a-PCB) for rapid, inexpensive, multiplex detection of disease biomarkers in real samples. It aims to overcome existing barriers for Lab-on-a-Chip commercialization (lack of cost effective mass manufacturing methods, self-contained, fully autonomous operation and user-friendliness). Different advanced techniques including electrochemical, optical, mass, colorimetric and signal amplification strategies describe early stage disease diagnosis. The book gathers scientific and technological novelties and advancements already developed or under development in the academic and research communities. It covers a vast audience from basic science to engineering and technology experts and learners. |
| the gene generation torrent: 68th AACC Annual Scientific Meeting Abstract eBook American Association for Clinical Chemistry, 2016-06-14 The poster abstracts presented at the 68th AACC Annual Scientific Meeting & Clinical Lab Expo and published in Clinical Chemistry, Vol. 62, No. 10, Supplement, 2016. |
Gene - Wikipedia
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional …
Home - Gene - NCBI - National Center for Biotechnology ...
Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to …
Gene | Journal | ScienceDirect.com by Elsevier
Gene publishes papers that focus on the regulation, expression, function, and evolution of genes in all biological contexts, including all prokaryotic and eukaryotic organisms, as well as viruses. …
Gene | Definition, Structure, Expression, & Facts | Britannica
May 18, 2025 · gene, unit of hereditary information that occupies a fixed position (locus) on a chromosome. Genes achieve their effects by directing the synthesis of proteins. In eukaryotes …
What is a gene? - MedlinePlus
May 21, 2024 · A gene is the basic physical and functional unit of heredity. Genes are made up of DNA. Some genes act as instructions to make molecules called proteins, which are needed for …
Gene - Definition and Examples - Biology Dictionary
Oct 27, 2020 · A gene is an extremely specific sequence of nucleotide monomers that has the ability to completely or partially control the expression of one or more traits in every type of …
Gene
Jun 9, 2025 · The gene is considered the basic unit of inheritance. Genes are passed from parents to offspring and contain the information needed to specify physical and biological …
Gene - Wikipedia
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional …
Home - Gene - NCBI - National Center for Biotechnology ...
Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to …
Gene | Journal | ScienceDirect.com by Elsevier
Gene publishes papers that focus on the regulation, expression, function, and evolution of genes in all biological contexts, including all prokaryotic and eukaryotic organisms, as well as viruses. …
Gene | Definition, Structure, Expression, & Facts | Britannica
May 18, 2025 · gene, unit of hereditary information that occupies a fixed position (locus) on a chromosome. Genes achieve their effects by directing the synthesis of proteins. In eukaryotes …
What is a gene? - MedlinePlus
May 21, 2024 · A gene is the basic physical and functional unit of heredity. Genes are made up of DNA. Some genes act as instructions to make molecules called proteins, which are needed for …
Gene - Definition and Examples - Biology Dictionary
Oct 27, 2020 · A gene is an extremely specific sequence of nucleotide monomers that has the ability to completely or partially control the expression of one or more traits in every type of …
Gene
Jun 9, 2025 · The gene is considered the basic unit of inheritance. Genes are passed from parents to offspring and contain the information needed to specify physical and biological …
