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statistics in epidemiology methods techniques and applications: Statistics in Epidemiology Hardeo Sahai, Anwer Khurshid, 1995-12-21 Epidemiologic studies provide research strategies for investigating public health and scientific questions relating to the factors that cause and prevent ailments in human populations. Statistics in Epidemiology: Methods, Techniques and Applications presents a comprehensive review of the wide range of principles, methods and techniques underlying prospective, retrospective and cross-sectional approaches to epidemiologic studies. Written for epidemiologists and other researchers without extensive backgrounds in statistics, this new book provides a clear and concise description of the statistical tools used in epidemiology. Emphasis is given to the application of these statistical tools, and examples are provided to illustrate direct methods for applying common statistical techniques in order to obtain solutions to problems. Statistics in Epidemiology: Methods, Techniques and Applications goes beyond the elementary material found in basic epidemiology and biostatistics books and provides a detailed account of techniques: |
statistics in epidemiology methods techniques and applications: Spatial Epidemiology Paul Elliott, 2000 Spatial epidemiology is concerned with describing, quantifying and explaining geographical variations in disease, especially with respect to variations in environmental exposures at the small-area scale. The recent and rapid expansion of the field looks set to continue in line with growing public, government and media concern about environment and health issues, and a scientific need to understand and explain the effects of environmental pollutants on health. This book brings together contributions from an international group of practitioners from a wide spectrum of disciplines including epidemiologists, statisticians, geographers, demographers and pollution modellers, providing a comprehensive reference on state-of-the-art methods and applications in the emerging field of spatial epidemiology. The book is divided into four sections. Section one gives an introduction to spatial epidemiological studies and summarises data requirements and problems with respect to modelling health events, including bias and confounding. Section two gives an overview of the state-of-the-art in statistical methodology, including Bayesian approaches to disease mapping, cluster detection, analysis of point exposures, geostatistical methods and methods for ecological correlation studies. Section three gives examples of disease mapping and cluster studies, involving mortality data, communicable disease data, Hodgkins disease, diabetes and childhood leukemias. Section four reviews methods ofexposure assessment for use in spatial epidemiological studies, and discusses possible links between exposure and health data in risk asessment, and in the effects on human health of traffic related pollution, water quality and climate change. This book aims to give an authoritative account of current practice and developments in the field. As such it should be of interest to epidemiologists, public health practitioners, statisticians, geographers, environmental scientists and others concerned with understanding the geographical distribution of disease and the effects of environmental exposures on human health. It will be a a valuable source for undergraduate and postgraduate coursees in epidemiology, medical geography, biostatistics, environmental health and environmental science as well as a useful source of reference for health policy makers, health economists, regulators and others in the field of environmental health. |
statistics in epidemiology methods techniques and applications: Epidemiology and Medical Statistics , 2007-11-21 This volume, representing a compilation of authoritative reviews on a multitude of uses of statistics in epidemiology and medical statistics written by internationally renowned experts, is addressed to statisticians working in biomedical and epidemiological fields who use statistical and quantitative methods in their work. While the use of statistics in these fields has a long and rich history, explosive growth of science in general and clinical and epidemiological sciences in particular have gone through a see of change, spawning the development of new methods and innovative adaptations of standard methods. Since the literature is highly scattered, the Editors have undertaken this humble exercise to document a representative collection of topics of broad interest to diverse users. The volume spans a cross section of standard topics oriented toward users in the current evolving field, as well as special topics in much need which have more recent origins. This volume was prepared especially keeping the applied statisticians in mind, emphasizing applications-oriented methods and techniques, including references to appropriate software when relevant.· Contributors are internationally renowned experts in their respective areas· Addresses emerging statistical challenges in epidemiological, biomedical, and pharmaceutical research· Methods for assessing Biomarkers, analysis of competing risks· Clinical trials including sequential and group sequential, crossover designs, cluster randomized, and adaptive designs· Structural equations modelling and longitudinal data analysis |
statistics in epidemiology methods techniques and applications: Statistical Methods in Epidemiology Harold A. Kahn, Christopher T. Sempos, 1989 This book is an expanded version of the Kahn's widely used text, An Introduction to Epidemiologic Methods (Oxford, 1983). It provides clear insight into the basic statistical tools used in epidemiology and is written so that those without advanced statistical training can comprehend the ideas underlying the analytical techniques. The authors emphasize the extent to which similar results are obtained from different methods, both simple and complex. To this edition they have added a new chapter on Comparison of Numerical Results for Various Methods of Adjustment and also one on The Primacy of Data Collection. New topics include the Kaplan-Meier product-limit method and the Cox proportional hazards model for analysis of time-related outcomes. An appendix of data from the Framingham Heart Study is used to illustrate the application of various analytical methods to an identical set of real data and provides source material for student exercises. The text has been updated throughout. |
statistics in epidemiology methods techniques and applications: International Encyclopedia of Statistical Science Miodrag Lovric, 2010-12-01 The goal of this book is multidimensional: a) to help reviving Statistics education in many parts in the world where it is in crisis. For the first time authors from many developing countries have an opportunity to write together with the most prominent world authorities. The editor has spent several years searching for the most reputable statisticians all over the world. International contributors are either presidents of the local statistical societies, or head of the Statistics department at the main university, or the most distinguished statisticians in their countries. b) to enable any non-statistician to obtain quick and yet comprehensive and highly understandable view on certain statistical term, method or application c) to enable all the researchers, managers and practicioners to refresh their knowledge in Statistics, especially in certain controversial fields. d) to revive interest in statistics among students, since they will see its usefulness and relevance in almost all branches of Science. |
statistics in epidemiology methods techniques and applications: Modern Methods for Epidemiology Yu-Kang Tu, Darren C. Greenwood, 2012-05-22 Routine applications of advanced statistical methods on real data have become possible in the last ten years because desktop computers have become much more powerful and cheaper. However, proper understanding of the challenging statistical theory behind those methods remains essential for correct application and interpretation, and rarely seen in the medical literature. Modern Methods for Epidemiology provides a concise introduction to recent development in statistical methodologies for epidemiological and biomedical researchers. Many of these methods have become indispensible tools for researchers working in epidemiology and medicine but are rarely discussed in details by standard textbooks of biostatistics or epidemiology. Contributors of this book are experienced researchers and experts in their respective fields. This textbook provides a solid starting point for those who are new to epidemiology, and for those looking for guidance in more modern statistical approaches to observational epidemiology. Epidemiological and biomedical researchers who wish to overcome the mathematical barrier of applying those methods to their research will find this book an accessible and helpful reference for self-learning and research. This book is also a good source for teaching postgraduate students in medical statistics or epidemiology. |
statistics in epidemiology methods techniques and applications: Scan Statistics Joseph Glaz, Vladimir Pozdnyakov, Sylvan Wallenstein, 2009-12-24 Scan statistics is currently one of the most active and important areas of research in applied probability and statistics, having applications to a wide variety of fields: archaeology, astronomy, bioinformatics, biosurveillance, molecular biology, genetics, computer science, electrical engineering, geography, material sciences, physics, reconnaissance, reliability and quality control, telecommunication, and epidemiology. Filling a gap in the literature, this self-contained volume brings together a collection of selected chapters illustrating the depth and diversity of theory, methods and applications in the area of scan statistics. |
statistics in epidemiology methods techniques and applications: Multivariate Methods in Epidemiology Theodore R. Holford, 2002-05-30 This text describes the statistical tools that are currently used to analyse epidemiologic data on the association between possible risk factors and the actual risk of disease. |
statistics in epidemiology methods techniques and applications: Epidemiology Mark Woodward, 2013-12-19 Highly praised for its broad, practical coverage, the second edition of this popular text incorporated the major statistical models and issues relevant to epidemiological studies. Epidemiology: Study Design and Data Analysis, Third Edition continues to focus on the quantitative aspects of epidemiological research. Updated and expanded, this edition shows students how statistical principles and techniques can help solve epidemiological problems. New to the Third Edition New chapter on risk scores and clinical decision rules New chapter on computer-intensive methods, including the bootstrap, permutation tests, and missing value imputation New sections on binomial regression models, competing risk, information criteria, propensity scoring, and splines Many more exercises and examples using both Stata and SAS More than 60 new figures After introducing study design and reviewing all the standard methods, this self-contained book takes students through analytical methods for both general and specific epidemiological study designs, including cohort, case-control, and intervention studies. In addition to classical methods, it now covers modern methods that exploit the enormous power of contemporary computers. The book also addresses the problem of determining the appropriate size for a study, discusses statistical modeling in epidemiology, covers methods for comparing and summarizing the evidence from several studies, and explains how to use statistical models in risk forecasting and assessing new biomarkers. The author illustrates the techniques with numerous real-world examples and interprets results in a practical way. He also includes an extensive list of references for further reading along with exercises to reinforce understanding. Web Resource A wealth of supporting material can be downloaded from the book’s CRC Press web page, including: Real-life data sets used in the text SAS and Stata programs used for examples in the text SAS and Stata programs for special techniques covered Sample size spreadsheet |
statistics in epidemiology methods techniques and applications: Advanced Statistics with Applications in R Eugene Demidenko, 2019-11-12 Advanced Statistics with Applications in R fills the gap between several excellent theoretical statistics textbooks and many applied statistics books where teaching reduces to using existing packages. This book looks at what is under the hood. Many statistics issues including the recent crisis with p-value are caused by misunderstanding of statistical concepts due to poor theoretical background of practitioners and applied statisticians. This book is the product of a forty-year experience in teaching of probability and statistics and their applications for solving real-life problems. There are more than 442 examples in the book: basically every probability or statistics concept is illustrated with an example accompanied with an R code. Many examples, such as Who said π? What team is better? The fall of the Roman empire, James Bond chase problem, Black Friday shopping, Free fall equation: Aristotle or Galilei, and many others are intriguing. These examples cover biostatistics, finance, physics and engineering, text and image analysis, epidemiology, spatial statistics, sociology, etc. Advanced Statistics with Applications in R teaches students to use theory for solving real-life problems through computations: there are about 500 R codes and 100 datasets. These data can be freely downloaded from the author's website dartmouth.edu/~eugened. This book is suitable as a text for senior undergraduate students with major in statistics or data science or graduate students. Many researchers who apply statistics on the regular basis find explanation of many fundamental concepts from the theoretical perspective illustrated by concrete real-world applications. |
statistics in epidemiology methods techniques and applications: Encyclopedia of Epidemiology Sarah Boslaugh, 2008 Presents information from the field of epidemiology in a less technical, more accessible format. Covers major topics in epidemiology, from risk ratios to case-control studies to mediating and moderating variables, and more. Relevant topics from related fields such as biostatistics and health economics are also included. |
statistics in epidemiology methods techniques and applications: Methods in Social Epidemiology J. Michael Oakes, Jay S. Kaufman, 2006-05-11 Social epidemiology is the study of how social interactions—social norms, laws, institutions, conventia, social conditions and behavior—affect the health of populations. This practical, comprehensive introduction to methods in social epidemiology is written by experts in the field. It is perfectly timed for the growth in interest among those in public health, community health, preventive medicine, sociology, political science, social work, and other areas of social research. Topics covered are: Introduction: Advancing Methods in Social Epidemiology The History of Methods of Social Epidemilogy to 1965 Indicators of Socioeconomic Position Measuring and Analyzing 'Race' Racism and Racial Discrimination Measuring Poverty Measuring Health Inequalities A Conceptual Framework for Measuring Segregation and its Association with Population Outcomes Measures of Residential Community Contexts Using Census Data to Approximate Neighborhood Effects Community-based Participatory Research: Rationale and Relevance for Social Epidemiology Network Methods in Social Epidemiology Identifying Social Interactions: A Review, Multilevel Studies Experimental Social Epidemiology: Controlled Community Trials Propensity Score Matching Methods for Social Epidemiology Natural Experiments and Instrumental Variable Analyses in Social Epidemiology and Using Causal Diagrams to Understand Common Problems in Social Epidemiology. Publication of this highly informative textbook clearly reflects the coming of age of many social epidemiology methods, the importance of which rests on their potential contribution to significantly improving the effectiveness of the population-based approach to prevention. This book should be of great interest not only to more advanced epidemiology students but also to epidemiologists in general, particularly those concerned with health policy and the translation of epidemiologic findings into public health practice. The cause of achieving a ‘more complete’ epidemiology envisaged by the editors has been significantly advanced by this excellent textbook. —Moyses Szklo, professor of epidemiology and editor-in-chief, American Journal of Epidemiology, Johns Hopkins University Social epidemiology is a comparatively new field of inquiry that seeks to describe and explain the social and geographic distribution of health and of the determinants of health. This book considers the major methodological challenges facing this important field. Its chapters, written by experts in a variety of disciplines, are most often authoritative, typically provocative, and often debatable, but always worth reading. —Stephen W. Raudenbush, Lewis-Sebring Distinguished Service Professor, Department of Sociology, University of Chicago The roadmap for a new generation of social epidemiologists. The publication of this treatise is a significant event in the history of the discipline. —Ichiro Kawachi, professor of social epidemiology, Department of Society, Human Development, and Health, Harvard University Methods in Social Epidemiology not only illuminates the difficult questions that future generations of social epidemiologists must ask, it also identifies the paths they must boldly travel in the pursuit of answers, if this exciting interdisciplinary science is to realize its full potential. This beautifully edited volume appears at just the right moment to exert a profound influence on the field. —Sherman A. James, Susan B. King Professor of Public Policy Studies, professor of Community and Family Medicine, professor of African-American Studies, Duke University |
statistics in epidemiology methods techniques and applications: Medical Uses of Statistics Bailar/Mostelle, 2019-05-20 This work explains the purpose of statistical methods in medical studies and analyzes the statistical techniques used by clinical investigators, with special emphasis on studies published in The New England Journal of Medicine. It clarifies fundamental concepts of statistical design and analysis, and facilitates the understanding of research results. |
statistics in epidemiology methods techniques and applications: Statistics in the Health Sciences Albert Vexler, Alan Hutson, 2018-01-19 This very informative book introduces classical and novel statistical methods that can be used by theoretical and applied biostatisticians to develop efficient solutions for real-world problems encountered in clinical trials and epidemiological studies. The authors provide a detailed discussion of methodological and applied issues in parametric, semi-parametric and nonparametric approaches, including computationally extensive data-driven techniques, such as empirical likelihood, sequential procedures, and bootstrap methods. Many of these techniques are implemented using popular software such as R and SAS.— Vlad Dragalin, Professor, Johnson and Johnson, Spring House, PA It is always a pleasure to come across a new book that covers nearly all facets of a branch of science one thought was so broad, so diverse, and so dynamic that no single book could possibly hope to capture all of the fundamentals as well as directions of the field. The topics within the book’s purview—fundamentals of measure-theoretic probability; parametric and non-parametric statistical inference; central limit theorems; basics of martingale theory; Monte Carlo methods; sequential analysis; sequential change-point detection—are all covered with inspiring clarity and precision. The authors are also very thorough and avail themselves of the most recent scholarship. They provide a detailed account of the state of the art, and bring together results that were previously scattered across disparate disciplines. This makes the book more than just a textbook: it is a panoramic companion to the field of Biostatistics. The book is self-contained, and the concise but careful exposition of material makes it accessible to a wide audience. This is appealing to graduate students interested in getting into the field, and also to professors looking to design a course on the subject. — Aleksey S. Polunchenko, Department of Mathematical Sciences, State University of New York at Binghamton This book should be appropriate for use both as a text and as a reference. This book delivers a ready-to-go well-structured product to be employed in developing advanced courses. In this book the readers can find classical and new theoretical methods, open problems and new procedures. The book presents biostatistical results that are novel to the current set of books on the market and results that are even new with respect to the modern scientific literature. Several of these results can be found only in this book. |
statistics in epidemiology methods techniques and applications: Measurement Error and Misclassification in Statistics and Epidemiology Paul Gustafson, 2003-09-25 Mismeasurement of explanatory variables is a common hazard when using statistical modeling techniques, and particularly so in fields such as biostatistics and epidemiology where perceived risk factors cannot always be measured accurately. With this perspective and a focus on both continuous and categorical variables, Measurement Error and Misclassi |
statistics in epidemiology methods techniques and applications: Statistical Methods in Diagnostic Medicine Xiao-Hua Zhou, Donna K. McClish, Nancy A. Obuchowski, 2009-09-25 An important role of diagnostic medicine research is to estimate and compare the accuracies of diagnostic tests. This book provides a comprehensive account of statistical methods for design and analysis of diagnostic studies, including sample size calculations, estimation of the accuracy of a diagnostic test, comparison of accuracies of competing diagnostic tests, and regression analysis of diagnostic accuracy data. Discussing recently developed methods for correction of verification bias and imperfect reference bias, methods for analysis of clustered diagnostic accuracy data, and meta-analysis methods, Statistical Methods in Diagnostic Medicine explains: * Common measures of diagnostic accuracy and designs for diagnostic accuracy studies * Methods of estimation and hypothesis testing of the accuracy of diagnostic tests * Meta-analysis * Advanced analytic techniques-including methods for comparing correlated ROC curves in multi-reader studies, correcting verification bias, and correcting when an imperfect gold standard is used Thoroughly detailed with numerous applications and end-of-chapter problems as well as a related FTP site providing FORTRAN program listings, data sets, and instructional hints, Statistical Methods in Diagnostic Medicine is a valuable addition to the literature of the field, serving as a much-needed guide for both clinicians and advanced students. |
statistics in epidemiology methods techniques and applications: Essential Statistical Methods for Medical Statistics J. Philip Miller, 2010-11-08 Essential Statistical Methods for Medical Statistics presents only key contributions which have been selected from the volume in the Handbook of Statistics: Medical Statistics, Volume 27 (2009). While the use of statistics in these fields has a long and rich history, the explosive growth of science in general, and of clinical and epidemiological sciences in particular, has led to the development of new methods and innovative adaptations of standard methods. This volume is appropriately focused for individuals working in these fields. Contributors are internationally renowned experts in their respective areas. - Contributors are internationally renowned experts in their respective areas - Addresses emerging statistical challenges in epidemiological, biomedical, and pharmaceutical research - Methods for assessing Biomarkers, analysis of competing risks - Clinical trials including sequential and group sequential, crossover designs, cluster randomized, and adaptive designs - Structural equations modelling and longitudinal data analysis |
statistics in epidemiology methods techniques and applications: A Statistical Approach to Genetic Epidemiology Andreas Ziegler, Inke R. Kônig, Friedrich Pahlke, 2010-06-14 Diese zweite Auflage des sehr erfolgreichen Lehrbuchs der Statistik in der genetischen Epidemiologie wurde sorgfältig durchgesehen, aktualisiert und an vielen Stellen erweitert. Wie gewohnt mit vielen Aufgaben und Lösungen, dazu jetzt auch Farbabbildungen und auf Wunsch gekoppelt mit einem maßgeschneiderten E-Learning-Kurs. |
statistics in epidemiology methods techniques and applications: Methods and Applications of Statistics in Business, Finance, and Management Science Narayanaswamy Balakrishnan, 2010-07-13 Inspired by the Encyclopedia of Statistical Sciences, Second Edition, this volume presents the tools and techniques that are essential for carrying out best practices in the modern business world The collection and analysis of quantitative data drives some of the most important conclusions that are drawn in today's business world, such as the preferences of a customer base, the quality of manufactured products, the marketing of products, and the availability of financial resources. As a result, it is essential for individuals working in this environment to have the knowledge and skills to interpret and use statistical techniques in various scenarios. Addressing this need, Methods and Applications of Statistics in Business, Finance, and Management Science serves as a single, one-of-a-kind resource that guides readers through the use of common statistical practices by presenting real-world applications from the fields of business, economics, finance, operations research, and management science. Uniting established literature with the latest research, this volume features classic articles from the acclaimed Encyclopedia of Statistical Sciences, Second Edition along with brand-new contributions written by today's leading academics and practitioners. The result is a compilation that explores classic methodology and new topics, including: Analytical methods for risk management Statistical modeling for online auctions Ranking and selection in mutual funds Uses of Black-Scholes formula in finance Data mining in prediction markets From auditing and marketing to stock market price indices and banking, the presented literature sheds light on the use of quantitative methods in research relating to common financial applications. In addition, the book supplies insight on common uses of statistical techniques such as Bayesian methods, optimization, simulation, forecasting, mathematical modeling, financial time series, and data mining in modern research. Providing a blend of traditional methodology and the latest research, Methods and Applications of Statistics in Business, Finance, and Management Science is an excellent reference for researchers, managers, consultants, and students in the fields of business, management science, operations research, supply chain management, mathematical finance, and economics who must understand statistical literature and carry out quantitative practices to make smart business decisions in their everyday work. |
statistics in epidemiology methods techniques and applications: Quantitative Methods for Health Research Nigel Bruce, Daniel Pope, Debbi Stanistreet, 2013-03-18 Quantitative Research Methods for Health Professionals: A Practical Interactive Course is a superb introduction to epidemiology, biostatistics, and research methodology for the whole health care community. Drawing examples from a wide range of health research, this practical handbook covers important contemporary health research methods such as survival analysis, Cox regression, and meta-analysis, the understanding of which go beyond introductory concepts. The book includes self-assessment exercises throughout to help students explore and reflect on their understanding and a clear distinction is made between a) knowledge and concepts that all students should ensure they understand and b) those that can be pursued by students who wish to do so. The authors incorporate a program of practical exercises in SPSS using a prepared data set that helps to consolidate the theory and develop skills and confidence in data handling, analysis and interpretation. |
statistics in epidemiology methods techniques and applications: Statistics in Medicine Robert H. Riffenburgh, Daniel L. Gillen, 2020-07-03 Statistics in Medicine, Fourth Edition, helps medical and biomedical investigators design and answer questions about analyzing and interpreting data and predicting the sample size required to achieve useful results. It makes medical statistics easy for the non-biostatistician by outlining common methods used in 90% of medical research. The text covers how to plan studies from conception to publication, what to do with data, and follows with step-by-step instructions for biostatistical methods from the simplest levels, to more sophisticated methods now used in medical articles. Examples from almost every medical specialty, and from dentistry, nursing, pharmacy and health care management are provided. This book does not require background knowledge of statistics or mathematics beyond high school algebra and provides abundant clinical examples and exercises to reinforce concepts. It is a valuable source for biomedical researchers, healthcare providers and anyone who conducts research or quality improvement projects. - Expands and revises important topics, such as basic concepts behind descriptive statistics and testing, descriptive statistics in three dimensions, the relationship between statistical testing and confidence intervals, and more - Presents an easy-to-follow format with medical examples, step-by-step methods and check-yourself exercises - Explains statistics for users with little statistical and mathematical background - Encompasses all research development stages, from conceiving a study, planning it in detail, carrying out the methods, putting obtained data in analyzable form, analyzing and interpreting the results, and publishing the study |
statistics in epidemiology methods techniques and applications: Methods of Clinical Epidemiology Suhail A. R. Doi, Gail M. Williams, 2013-06-01 “Methods of Clinical Epidemiology” serves as a text on methods useful to clinical researchers. It provides a clear introduction to the common research methodology specific to clinical research for both students and researchers. This book sets out to fill the gap left by texts that concentrate on public health epidemiology and focuses on what is not covered well in such texts. The four sections cover methods that have not previously been brought together in one text and serves as a second level textbook of clinical epidemiology methodology. This book will be of use to postgraduate students in clinical epidemiology as well as clinical researchers at the start of their careers. |
statistics in epidemiology methods techniques and applications: Biostatistics in Public Health Using STATA Erick L. Suárez, Cynthia M. Pérez, Graciela M. Nogueras, Camille Moreno-Gorrín, 2016-03-24 Striking a balance between theory, application, and programming, Biostatistics in Public Health Using STATA is a user-friendly guide to applied statistical analysis in public health using STATA version 14. The book supplies public health practitioners and students with the opportunity to gain expertise in the application of statistics in epidemiologic studies. The book shares the authors’ insights gathered through decades of collective experience teaching in the academic programs of biostatistics and epidemiology. Maintaining a focus on the application of statistics in public health, it facilitates a clear understanding of the basic commands of STATA for reading and saving databases. The book includes coverage of data description, graph construction, significance tests, linear regression models, analysis of variance, categorical data analysis, logistic regression model, poisson regression model, survival analysis, analysis of correlated data, and advanced programming in STATA. Each chapter is based on one or more research problems linked to public health. Additionally, every chapter includes exercise sets for practicing concepts and exercise solutions for self or group study. Several examples are presented that illustrate the applications of the statistical method in the health sciences using epidemiologic study designs. Presenting high-level statistics in an accessible manner across research fields in public health, this book is suitable for use as a textbook for biostatistics and epidemiology courses or for consulting the statistical applications in public health. For readers new to STATA, the first three chapters should be read sequentially, as they form the basis of an introductory course to this software. |
statistics in epidemiology methods techniques and applications: Statistics for Epidemiology Nicholas P. Jewell, 2003-08-26 Statistical ideas have been integral to the development of epidemiology and continue to provide the tools needed to interpret epidemiological studies. Although epidemiologists do not need a highly mathematical background in statistical theory to conduct and interpret such studies, they do need more than an encyclopedia of recipes. Statistics for Epidemiology achieves just the right balance between the two approaches, building an intuitive understanding of the methods most important to practitioners and the skills to use them effectively. It develops the techniques for analyzing simple risk factors and disease data, with step-by-step extensions that include the use of binary regression. It covers the logistic regression model in detail and contrasts it with the Cox model for time-to-incidence data. The author uses a few simple case studies to guide readers from elementary analyses to more complex regression modeling. Following these examples through several chapters makes it easy to compare the interpretations that emerge from varying approaches. Written by one of the top biostatisticians in the field, Statistics for Epidemiology stands apart in its focus on interpretation and in the depth of understanding it provides. It lays the groundwork that all public health professionals, epidemiologists, and biostatisticians need to successfully design, conduct, and analyze epidemiological studies. |
statistics in epidemiology methods techniques and applications: Bayesian Methods in Epidemiology Lyle D. Broemeling, 2013-08-13 Written by a biostatistics expert with over 20 years of experience in the field, Bayesian Methods in Epidemiology presents statistical methods used in epidemiology from a Bayesian viewpoint. It employs the software package WinBUGS to carry out the analyses and offers the code in the text and for download online.The book examines study designs that |
statistics in epidemiology methods techniques and applications: Propensity Score Analysis Shenyang Guo, Mark W. Fraser, 2015 Provides readers with a systematic review of the origins, history, and statistical foundations of Propensity Score Analysis (PSA) and illustrates how it can be used for solving evaluation and causal-inference problems. |
statistics in epidemiology methods techniques and applications: Testing Statistical Hypotheses Erich L. Lehmann, Joseph P. Romano, 2006-03-30 The third edition of Testing Statistical Hypotheses updates and expands upon the classic graduate text, emphasizing optimality theory for hypothesis testing and confidence sets. The principal additions include a rigorous treatment of large sample optimality, together with the requisite tools. In addition, an introduction to the theory of resampling methods such as the bootstrap is developed. The sections on multiple testing and goodness of fit testing are expanded. The text is suitable for Ph.D. students in statistics and includes over 300 new problems out of a total of more than 760. |
statistics in epidemiology methods techniques and applications: Biostatistics Wayne W. Daniel, Chad L. Cross, 2018-11-13 The ability to analyze and interpret enormous amounts of data has become a prerequisite for success in allied healthcare and the health sciences. Now in its 11th edition, Biostatistics: A Foundation for Analysis in the Health Sciences continues to offer in-depth guidance toward biostatistical concepts, techniques, and practical applications in the modern healthcare setting. Comprehensive in scope yet detailed in coverage, this text helps students understand—and appropriately use—probability distributions, sampling distributions, estimation, hypothesis testing, variance analysis, regression, correlation analysis, and other statistical tools fundamental to the science and practice of medicine. Clearly-defined pedagogical tools help students stay up-to-date on new material, and an emphasis on statistical software allows faster, more accurate calculation while putting the focus on the underlying concepts rather than the math. Students develop highly relevant skills in inferential and differential statistical techniques, equipping them with the ability to organize, summarize, and interpret large bodies of data. Suitable for both graduate and advanced undergraduate coursework, this text retains the rigor required for use as a professional reference. |
statistics in epidemiology methods techniques and applications: Advanced Medical Statistics (2nd Edition) Ying Lu, Ji-qian Fang, Lu Tian, Hua Jin, 2015-06-29 The book aims to provide both comprehensive reviews of the classical methods and an introduction to new developments in medical statistics. The topics range from meta analysis, clinical trial design, causal inference, personalized medicine to machine learning and next generation sequence analysis. Since the publication of the first edition, there have been tremendous advances in biostatistics and bioinformatics. The new edition tries to cover as many important emerging areas and reflect as much progress as possible. Many distinguished scholars, who greatly advanced their research areas in statistical methodology as well as practical applications, also have revised several chapters with relevant updates and written new ones from scratch.The new edition has been divided into four sections, including, Statistical Methods in Medicine and Epidemiology, Statistical Methods in Clinical Trials, Statistical Genetics, and General Methods. To reflect the rise of modern statistical genetics as one of the most fertile research areas since the publication of the first edition, the brand new section on Statistical Genetics includes entirely new chapters reflecting the state of the art in the field.Although tightly related, all the book chapters are self-contained and can be read independently. The book chapters intend to provide a convenient launch pad for readers interested in learning a specific topic, applying the related statistical methods in their scientific research and seeking the newest references for in-depth research. |
statistics in epidemiology methods techniques and applications: Statistical Analysis of Human Growth and Development Yin Bun Cheung, 2013-10-28 Statistical Analysis of Human Growth and Development is an accessible and practical guide to a wide range of basic and advanced statistical methods that are useful for studying human growth and development. Designed for nonstatisticians and statisticians new to the analysis of growth and development data, the book collects methods scattered throughout the literature and explains how to use them to solve common research problems. It also discusses how well a method addresses a specific scientific question and how to interpret and present the analytic results. Stata is used to implement the analyses, with Stata codes and macros for generating example data sets, a detrended Q-Q plot, and weighted maximum likelihood estimation of binary items available on the book’s CRC Press web page. After reviewing research designs and basic statistical tools, the author discusses the use of existing tools to transform raw data into analyzable variables and back-transform them to raw data. He covers regression analysis of quantitative, binary, and censored data as well as the analysis of repeated measurements and clustered data. He also describes the development of new growth references and developmental indices, the generation of key variables based on longitudinal data, and the processes to verify the validity and reliability of measurement tools. Looking at the larger picture of research practice, the book concludes with coverage of missing values, multiplicity problems, and multivariable regression. Along with two simulated data sets, numerous examples from real experimental and observational studies illustrate the concepts and methods. Although the book focuses on examples of anthropometric measurements and changes in cognitive, social-emotional, locomotor, and other abilities, the ideas are applicable to many other physical and psychosocial phenomena, such as lung function and depressive symptoms. |
statistics in epidemiology methods techniques and applications: Biostatistics for Epidemiology and Public Health Using R Bertram K.C. Chan, PhD, 2015-11-05 Since it first appeared in 1996, the open-source programming language R has become increasingly popular as an environment for statistical analysis and graphical output. In addition to being freely available, R offers several advantages for biostatistics, including strong graphics capabilities, the ability to write customized functions, and its extensibility. This is the first textbook to present classical biostatistical analysis for epidemiology and related public health sciences to students using the R language. Based on the assumption that readers have minimal familiarity with statistical concepts, the author uses a step-bystep approach to building skills. The text encompasses biostatistics from basic descriptive and quantitative statistics to survival analysis and missing data analysis in epidemiology. Illustrative examples, including real-life research problems and exercises drawn from such areas as nutrition, environmental health, and behavioral health, engage students and reinforce the understanding of R. These examples illustrate the replication of R for biostatistical calculations and graphical display of results. The text covers both essential and advanced techniques and applications in biostatistics that are relevant to epidemiology. This text is supplemented with teaching resources, including an online guide for students in solving exercises and an instructor's manual. KEY FEATURES: First overview biostatistics textbook for epidemiology and public health that uses the open-source R program Covers essential and advanced techniques and applications in biostatistics as relevant to epidemiology Features abundant examples and exercises to illustrate the application of R language for biostatistical calculations and graphical displays of results Includes online student solutions guide and instructor's manual |
statistics in epidemiology methods techniques and applications: Pediatric Epidemiology W. Kiess, C.-G. Bornehag, C. Gennings, 2017-11-27 Pediatric epidemiology differs substantially from general epidemiology especially when it comes to ethical, developmental and societal aspects. This unique book addresses biological considerations and ethical and legal questions in dealing with pediatric and adolescent populations. Classic topics, such as how to recruit representative samples, how to deal with confounding variables, and how to work with genetic information are the core areas of the book are also in focus. Last but not the least, this volume adds to the current understanding of global trends in occurrence, transmission, and control of epidemic pediatric diseases. This book not only serves as a textbook for epidemiologists, pediatricians, geneticists, and child and public health specialists but is also a key reference for those embarking on pediatric cohort studies and epidemiological studies involving the pediatric population. |
statistics in epidemiology methods techniques and applications: Spatial Analysis in Epidemiology Dirk U. Pfeiffer, Timothy P. Robinson, Mark Stevenson, Kim B. Stevens, David J. Rogers, Archie C. A. Clements, 2008-05-29 This book provides a practical, comprehensive and up-to-date overview of the use of spatial statistics in epidemiology - the study of the incidence and distribution of diseases. Used appropriately, spatial analytical methods in conjunction with GIS and remotely sensed data can provide significant insights into the biological patterns and processes that underlie disease transmission. In turn, these can be used to understand and predict disease prevalence. This user-friendly text brings together the specialised and widely-dispersed literature on spatial analysis to make these methodological tools accessible to epidemiologists for the first time. With its focus is on application rather than theory, Spatial Analysis in Epidemiology includes a wide range of examples taken from both medical (human) and veterinary (animal) disciplines, and describes both infectious diseases and non-infectious conditions. Furthermore, it provides worked examples of methodologies using a single data set from the same disease example throughout, and is structured to follow the logical sequence of description of spatial data, visualisation, exploration, modelling and decision support. This accessible text is aimed at graduate students and researchers dealing with spatial data in the fields of epidemiology (both medical and veterinary), ecology, zoology and parasitology, environmental science, geography and statistics. |
statistics in epidemiology methods techniques and applications: Molecular Tools and Infectious Disease Epidemiology Betsy Foxman, 2010-12-28 Molecular Tools and Infectious Disease Epidemiology examines the opportunities and methodologic challenges in the application of modern molecular genetic and biologic techniques to infectious disease epidemiology. The application of these techniques dramatically improves the measurement of disease and putative risk factors, increasing our ability to detect and track outbreaks, identify risk factors and detect new infectious agents. However, integration of these techniques into epidemiologic studies also poses new challenges in the design, conduct, and analysis. This book presents the key points of consideration when integrating molecular biology and epidemiology; discusses how using molecular tools in epidemiologic research affects program design and conduct; considers the ethical concerns that arise in molecular epidemiologic studies; and provides a context for understanding and interpreting scientific literature as a foundation for subsequent practical experience in the laboratory and in the field. The book is recommended for graduate and advanced undergraduate students studying infectious disease epidemiology and molecular epidemiology; and for the epidemiologist wishing to integrate molecular techniques into his or her studies. - Presents the key points of consideration when integrating molecular biology and epidemiology - Discusses how using molecular tools in epidemiologic research affects program design and conduct - Considers the ethical concerns that arise in molecular epidemiologic studies - Provides a context for understanding and interpreting scientific literature as a foundation for subsequent practical experience in the laboratory and in the field |
statistics in epidemiology methods techniques and applications: Analysis of Incidence Rates Peter Cummings, 2019-04-16 Incidence rates are counts divided by person-time; mortality rates are a well-known example. Analysis of Incidence Rates offers a detailed discussion of the practical aspects of analyzing incidence rates. Important pitfalls and areas of controversy are discussed. The text is aimed at graduate students, researchers, and analysts in the disciplines of epidemiology, biostatistics, social sciences, economics, and psychology. Features: Compares and contrasts incidence rates with risks, odds, and hazards. Shows stratified methods, including standardization, inverse-variance weighting, and Mantel-Haenszel methods Describes Poisson regression methods for adjusted rate ratios and rate differences. Examines linear regression for rate differences with an emphasis on common problems. Gives methods for correcting confidence intervals. Illustrates problems related to collapsibility. Explores extensions of count models for rates, including negative binomial regression, methods for clustered data, and the analysis of longitudinal data. Also, reviews controversies and limitations. Presents matched cohort methods in detail. Gives marginal methods for converting adjusted rate ratios to rate differences, and vice versa. Demonstrates instrumental variable methods. Compares Poisson regression with the Cox proportional hazards model. Also, introduces Royston-Parmar models. All data and analyses are in online Stata files which readers can download. Peter Cummings is Professor Emeritus, Department of Epidemiology, School of Public Health, University of Washington, Seattle WA. His research was primarily in the field of injuries. He used matched cohort methods to estimate how the use of seat belts and presence of airbags were related to death in a traffic crash. He is author or co-author of over 100 peer-reviewed articles. |
statistics in epidemiology methods techniques and applications: Design of Experiments and Advanced Statistical Techniques in Clinical Research Basavarajaiah D. M., Bhamidipati Narasimha Murthy, 2020-11-05 Recent Statistical techniques are one of the basal evidence for clinical research, a pivotal in handling new clinical research and in evaluating and applying prior research. This book explores various choices of statistical tools and mechanisms, analyses of the associations among different clinical attributes. It uses advanced statistical methods to describe real clinical data sets, when the clinical processes being examined are still in the process. This book also discusses distinct methods for building predictive and probability distribution models in clinical situations and ways to assess the stability of these models and other quantitative conclusions drawn by realistic experimental data sets. Design of experiments and recent posthoc tests have been used in comparing treatment effects and precision of the experimentation. This book also facilitates clinicians towards understanding statistics and enabling them to follow and evaluate the real empirical studies (formulation of randomized control trial) that pledge insight evidence base for clinical practices. This book will be a useful resource for clinicians, postgraduates scholars in medicines, clinical research beginners and academicians to nurture high-level statistical tools with extensive scope. |
statistics in epidemiology methods techniques and applications: Introduction to Statistics and Data Analysis Christian Heumann, Michael Schomaker, Shalabh, 2023-01-30 Now in its second edition, this introductory statistics textbook conveys the essential concepts and tools needed to develop and nurture statistical thinking. It presents descriptive, inductive and explorative statistical methods and guides the reader through the process of quantitative data analysis. This revised and extended edition features new chapters on logistic regression, simple random sampling, including bootstrapping, and causal inference. The text is primarily intended for undergraduate students in disciplines such as business administration, the social sciences, medicine, politics, and macroeconomics. It features a wealth of examples, exercises and solutions with computer code in the statistical programming language R, as well as supplementary material that will enable the reader to quickly adapt the methods to their own applications. |
statistics in epidemiology methods techniques and applications: Handbook of Spatial Epidemiology Andrew B. Lawson, Sudipto Banerjee, Robert P. Haining, María Dolores Ugarte, 2016 This handbook explains how to model epidemiological problems and improve inference about disease etiology from a geographical perspective. Top epidemiologists, geographers, and statisticians share interdisciplinary viewpoints on analyzing spatial data and space-time variations in disease incidences. The book explores the use of GIS and spatial statistics as tools for the analysis of spatial epidemiological data. It covers methodological advances as well as applications in human and veterinary epidemiology. A supplementary website provides color figures, program code, and datasets. |
statistics in epidemiology methods techniques and applications: Epidemiology and the Delivery of Health Care Services Denise M. Oleske, 2009-09-18 This completely revised and updated edition of an outstanding text addresses the fundamental knowledge of epidemiological methods and statistics that can be applied to evolving systems, programs, technologies, and policies. This edition presents new chapters on causal thinking, ethics, and web resources, analyzes data on multinational increases in poverty and longevity, details the control of transmissible diseases, and explains quality management, and the evaluation of healthcare system performance. |
statistics in epidemiology methods techniques and applications: Exact Analysis of Discrete Data Karim F. Hirji, 2005-11-18 Researchers in fields ranging from biology and medicine to the social sciences, law, and economics regularly encounter variables that are discrete or categorical in nature. While there is no dearth of books on the analysis and interpretation of such data, these generally focus on large sample methods. When sample sizes are not large or the data are |
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Statista - The Statistics Portal for Market Data, Market Research …
Jun 5, 2025 · Find statistics, consumer survey results and industry studies from over 22,500 sources on over 60,000 topics on the internet's leading statistics database
United States - Statistics & Facts | Statista
Feb 27, 2025 · Demographics With a total population of around 335 million people, the United States is the third most populous country in the world, behind India and China.Fertility rates …
Conflicts worldwide 2025 - statistics & facts | Statista
May 30, 2025 · Annual car sales worldwide 2010-2023, with a forecast for 2024; Monthly container freight rate index worldwide 2023-2024; Automotive manufacturers' estimated market share in …
U.S. tariffs - statistics & facts | Statista
May 15, 2025 · Detailed statistics U.S. top five imported products 2023, by type of product and country of origin Share of Americans who approve of a 25 percent tariff on Mexican and …
Industry Overview - Statista
Find statistics, consumer survey results and industry studies from over 22,500 sources on over 60,000 topics on the internet's leading statistics database
Statista China | Statista
Statistics. Statista数据平台提供来自22,500多个数据源的80,000个不同主题的统计数据和预测,并不断实时更新。 ...
2024 U.S. Presidential Election - statistics & facts | Statista
Nov 4, 2024 · Detailed statistics Forecasted electoral votes earned by U.S. presidential candidates, by lean 2024 Share of adults aged 35 to 49 motivated to vote in 2024 than 2020 in …
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Most viewed statistics. Recent Statistics Popular Statistics. Annual car sales worldwide 2010-2023, with a forecast for 2024; Monthly container freight rate index worldwide 2023-2024;
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Death rate disparities 9 Basic Statistic Leading causes of death among children aged 5-9 years in the United States 2020-2022 Basic Statistic Leading causes of death among children aged 10 …