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| sliding filament theory summary: The Sliding-Filament Theory of Muscle Contraction David Aitchison Smith, 2019-02-05 Understanding the molecular mechanism of muscle contraction started with the discovery that striated muscle is composed of interdigitating filaments which slide against each other. Sliding filaments and the working-stroke mechanism provide the framework for individual myosin motors to act in parallel, generating tension and loaded shortening with an efficient use of chemical energy. Our knowledge of this exquisitely structured molecular machine has exploded in the last four decades, thanks to a bewildering array of techniques for studying intact muscle, muscle fibres, myofibrils and single myosin molecules. After reviewing the mechanical and biochemical background, this monograph shows how old and new experimental discoveries can be modelled, interpreted and incorporated into a coherent mathematical theory of contractility at the molecular level. The theory is applied to steady-state and transient phenomena in muscle fibres, wing-beat oscillations in insect flight muscle, motility assays and single-molecule experiments with optical trapping. Such a synthesis addresses major issues, most notably whether a single myosin motor is driven by a working stroke or a ratchet mechanism, how the working stroke is coupled to phosphate release, and whether one cycle of attachment is driven by the hydrolysis of one molecule of ATP. Ways in which the theory can be extended are explored in appendices. A separate theory is required for the cooperative regulation of muscle by calcium via tropomyosin and troponin on actin filaments. The book reviews the evolution of models for actin-based regulation, culminating in a model motivated by cryo-EM studies where tropomyosin protomers are linked to form a continuous flexible chain. It also explores muscle behaviour as a function of calcium level, including emergent phenomena such as spontaneous oscillatory contractions and direct myosin regulation by its regulatory light chains. Contraction models can be extended to all levels of calcium-activation by embedding them in a cooperative theory of thin-filament regulation, and a method for achieving this grand synthesis is proposed. Dr. David Aitchison Smith is a theoretical physicist with thirty years of research experience in modelling muscle contractility, in collaboration with experimental groups in different laboratories. |
| sliding filament theory summary: Anatomy & Physiology Lindsay Biga, Devon Quick, Sierra Dawson, Amy Harwell, Robin Hopkins, Joel Kaufmann, Mike LeMaster, Philip Matern, Katie Morrison-Graham, Jon Runyeon, 2019-09-26 A version of the OpenStax text |
| sliding filament theory summary: Mechanism of Muscular Contraction Jack A. Rall, 2014-10-21 This book describes the evolution of ideas relating to the mechanism of muscular contraction since the discovery of sliding filaments in 1954. An amazing variety of experimental techniques have been employed to investigate the mechanism of muscular contraction and relaxation. Some background of these various techniques is presented in order to gain a fuller appreciation of their strengths and weaknesses. Controversies in the muscle field are discussed along with some missed opportunities and false trails. The pathway to ATP and the high energy phosphate bond will be discussed, as well as the discovery of myosin, contraction coupling and the emergence of cell and molecular biology in the muscle field. Numerous figures from original papers are also included for readers to see the data that led to important conclusions. This book is published on behalf of the American Physiological Society by Springer. Access to APS books published with Springer is free to APS members. |
| sliding filament theory summary: Basic Physiology for Anaesthetists David Chambers, Christopher Huang, Gareth Matthews, 2019-07-25 Every trainee in anaesthesia requires a thorough understanding of basic physiology and its application to clinical practice. Now in its second edition, this comprehensively illustrated textbook bridges the gap between medical school and reference scientific texts. It covers the physiology requirements of the Primary FRCA examination syllabus. Chapters are organised by organ system, with particular emphasis given to the respiratory, cardiovascular and nervous systems. The practical question-and-answer format helps the reader prepare for oral examinations, while 'clinical relevance' boxes translate the physiological concepts to clinical practice. This new edition has been thoroughly updated and revised throughout, and includes six new chapters, including the physiology of the eye, upper airway and exercise testing. It provides junior anaesthetists with an essential 'one stop' physiology resource. |
| sliding filament theory summary: Pharmacology of Neuromuscular Function W. C. Bowman, 1990 Pharmacology of Neuromuscular Function, Second Edition provides information pertinent to drugs that affect membrane potentials of the conduction of action potentials in nerve endings and muscle fibers. This book reviews, in a general way, some of the properties of excitable membranes. Organized into seven chapters, this edition begins with an overview of innervation of striated muscles by somatic efferent nerve fibers. This text then explains the transmission from nerve to muscle, which is mediated by acetylcholine that is synthesized and stored in the axon terminals. Other chapters consider t ... |
| sliding filament theory summary: Biomechanics of Skeletal Muscles Vladimir M. Zatsiorsky, Boris I. Prilutsky, 2012-04-10 Richly illustrated and presented in clear, concise language, Biomechanics of Skeletal Muscles is an essential resource for those seeking advanced knowledge of muscle biomechanics. Written by leading experts Vladimir Zatsiorsky and Boris Prilutsky, the text is one of the few to look at muscle biomechanics in its entirety—from muscle fibers to muscle coordination—making it a unique contribution to the field. Using a blend of experimental evidence and mechanical models, Biomechanics of Skeletal Muscles provides an explanation of whole muscle biomechanics at work in the body in motion. The book first addresses the mechanical behavior of single muscles—from the sarcomere level up to the entire muscle. The architecture of human muscle, the mechanical properties of tendons and passive muscles, the biomechanics of active muscles, and the force transmission and shock absorption aspects of muscle are explored in detail. Next, the various issues of muscle functioning during human motion are addressed. The transformation from muscle force to joint movements, two-joint muscle function, eccentric muscle action, and muscle coordination are analyzed. This advanced text assumes some knowledge of algebra and calculus; however, the emphasis is on understanding physical concepts. Higher-level computational descriptions are placed in special sections in the later chapters of the book, allowing those with a strong mathematical background to explore this material in more detail. Readers who choose to skip over these sections will find that the book still provides a strong conceptual understanding of advanced topics. Biomechanics of Skeletal Muscles also contains numerous special features that facilitate readers’ comprehension of the topics presented. More than 300 illustrations and accompanying explanations provide an extensive visual representation of muscle biomechanics. Refresher sidebars offer brief reminders of mathematical and biomechanical concepts, and From the Literature sidebars present practical examples that illustrate the concepts under discussion. Chapter summaries and review questions provide an opportunity for reflection and self-testing, and reference lists at the end of each chapter provide a starting point for further study. Biomechanics of Skeletal Muscles offers a thorough explanation of whole muscle biomechanics, bridging the gap between foundational biomechanics texts and scientific literature. With the information found in this text, readers can prepare themselves to better understand the latest in cutting-edge research. Biomechanics of Skeletal Muscles is the third volume in the Biomechanics of Human Motion series. Advanced readers in human movement science gain a comprehensive understanding of the biomechanics of human motion as presented by one of the world’s foremost researchers on the subject, Dr. Vladimir Zatsiorsky. The series begins with Kinematics of Human Motion, which details human body positioning and movement in three dimensions; continues with Kinetics of Human Motion, which examines the forces that create body motion and their effects; and concludes with Biomechanics of Skeletal Muscles, which explains the action of the biological motors that exert force and produce mechanical work during human movement. |
| sliding filament theory summary: Muscle Atrophy Junjie Xiao, 2018-11-02 The book addresses the development of muscle atrophy, which can be caused by denervation, disuse, excessive fasting, aging, and a variety of diseases including heart failure, chronic kidney diseases and cancers. Muscle atrophy reduces quality of life and increases morbidity and mortality worldwide. The book is divided into five parts, the first of which describes the general aspects of muscle atrophy including its characteristics, related economic and health burdens, and the current clinical therapy. Secondly, basic aspects of muscle atrophy including the composition, structure and function of skeletal muscle, muscle changes in response to atrophy, and experimental models are summarized. Thirdly, the book reviews the molecular mechanisms of muscle atrophy, including protein degradation and synthesis pathways, noncoding RNAs, inflammatory signaling, oxidative stress, mitochondria signaling, etc. Fourthly, it highlights the pathophysiological mechanisms of muscle atrophy in aging and disease. The book’s fifth and final part covers the diagnosis, treatment strategies, promising agents and future prospects of muscle atrophy. The book will appeal to a broad readership including scientists, undergraduate and graduate students in medicine and cell biology. |
| sliding filament theory summary: Keynes & Aidley's Nerve and Muscle Christopher L.-H. Huang, 2020-11-19 This well-established and acclaimed textbook introducing the rapidly growing field of nerve and muscle function has been completely revised and updated. Written with undergraduate students in mind, it begins with the fundamental principles demonstrated by the pioneering electrophysiological experiments on cell excitability. This leads to more challenging material recounting recent discoveries from applying modern biochemical, genetic, physiological and biophysical, experimental and mathematical analysis. The resulting interdisciplinary approach conveys a unified contemporary understanding of nerve and skeletal, cardiac and smooth muscle function at the molecular, cellular and systems levels. Emphasis on important strategic experiments throughout clarifies the basis for our current scientific views, highlights the excitement and challenge of biomedical discovery, and suggests directions for future advances. These fundamental ideas are then translated into discussions of related disease conditions and their clinical management. Now including colour illustrations, it is an invaluable text for students of physiology, neuroscience, cell biology and biophysics. |
| sliding filament theory summary: Encyclopedia of Exercise Medicine in Health and Disease Frank C. Mooren, 2012-04-19 The Encyclopedia of Exercise Medicine is intelligently structured, easy accessible and user-friendly: A-Z format, clear, concise language and uniform essay structure as well as extensive cross references between keywords and related articles enables efficient searches in a user-friendly manner both for experts and newcomers. It is intended to be a comprehensive up-to-date data base on the adaptation of the human body to exercise and on the therapeutic use of exercise with up to 2,000 keywords. It covers all aspects within the full range of modern exercise medicine of each particular scientific discipline (cancer, parasitology, aging, etc.). This includes information on methodological approaches to measuring the principle components of motor fitness, and practical aspects of their enhancement by trainings regimes as well as by nutrition and the application of drugs. Such a wide range of entries, all written by leading experts in their respective fields, will therefore address both the basic/clinical scientist as well as the practitioner. Moreover, the Encyclopedia of Exercise Medicine is aimed at people in related fields, health care professionals, physiotherapists, trainers, students, informed athletes and interested laypersons. It is available both in print and as a fully searchable and hyperlinked electronic online edition. |
| sliding filament theory summary: Excitation-Contraction Coupling in Skeletal, Cardiac, and Smooth Muscle George B. Frank, C. Paul Bianchi, Henk Keurs, 2012-12-06 The Third International Symposium on Excitation-Contraction Coupling in Skeletal, Cardiac, and Smooth Muscle, organized by George Frank, C. Paul Bianchi, and Henk E. DJ. ter Keurs, was held in Banff Centre, Banff, Alberta, Canada during June 26 to June 30, 1991. The theme of these symposia has been to recognize the similarities and dissimilarities of excitation-contraction coupling in skeletal, cardiac, and smooth muscle. Cross fertilization of concepts of excitation-contraction coupling in these three types of muscle has occurred since the early studies in the late fifties and early sixties on skeletal muscle. Investigators in each field meet only at specialized symposia which exclude investigators in the other fields. The purpose of the symposia has been to bring together international investigators studying excitation-contraction coupling in skeletal, cardiac, and smooth muscle so that we may learn from each other and hence provide a more global concept of excitation-contraction. The Third International Symposia has accomplished its objective as we recognize that calcium channels of the sarcolemma and the sarcoplasmic reticulum play key essential roles in excitation-contraction coupling in all three types of muscles. In skeletal muscle the recognition that E-C coupling consists of two parallel mechanisms, one dependent upon a dihydropyridine voltage-sensitive sensors coupled to calcium release from the terminal cisternae via the ryanodine sensitive channel in the foot structure of the triad. |
| sliding filament theory summary: Kinesiology Carol A. Oatis, 2009 The Second Edition of Kinesiology: The Mechanics and Pathomechanics of Human Movement relates the most current understanding of anatomy and mechanics with clinical practice concerns. Featuring seven chapters devoted to biomechanics, straightforward writing, and over 900 beautiful illustrations, the text provides you with detailed coverage of the structure, function, and kinesiology of each body region. You will gain an in-depth understanding of the relationship between the quality of movement and overall human health. Special features include: New DVD containing about 150 videos provides dynamic examples of clinical demonstrations, principle illustrations, and lab activities. This powerful resource explores patient function, dysfunction, and injury for greater comprehension. Clinical Relevance Boxes reinforce the relationship of biomechanical principles to patient care through real-life case studies. Muscle Attachment Boxes provide easily accessed anatomical information and tips on muscle palpation Examining the Forces Boxes highlight the advanced mathematical concepts used to determine forces on joint structure. Evidence-based presentations deliver the most current literature and essential classic studies for your understanding of musculoskeletal structure and function. Whether you are a student or practitioner in the field of physical therapy, occupational therapy, or exercise science, this comprehensive book serves as an excellent resource for best practice techniques. |
| sliding filament theory summary: Mechanics of Motor Proteins and the Cytoskeleton Jonathon Howard, 2005-12-06 Mechanics of Motor Proteins and the Cytoskeleton provides a physical foundation for molecular mechanics. Part I explains how small particles like proteins respond to mechanical, thermal, and chemical forces, Part II focuses on cytoskeletal filaments, and Part III focuses on motor proteins. The treatments are unified in the respect that they are organized around principles rather than proteins: chapters are centred on topics such as structure, chemistry, and mechanics, and different filaments or motors are discussed together. |
| sliding filament theory summary: Wind Energy Explained James F. Manwell, Jon G. McGowan, Anthony L. Rogers, 2010-09-14 Wind energy’s bestselling textbook- fully revised. This must-have second edition includes up-to-date data, diagrams, illustrations and thorough new material on: the fundamentals of wind turbine aerodynamics; wind turbine testing and modelling; wind turbine design standards; offshore wind energy; special purpose applications, such as energy storage and fuel production. Fifty additional homework problems and a new appendix on data processing make this comprehensive edition perfect for engineering students. This book offers a complete examination of one of the most promising sources of renewable energy and is a great introduction to this cross-disciplinary field for practising engineers. “provides a wealth of information and is an excellent reference book for people interested in the subject of wind energy.” (IEEE Power & Energy Magazine, November/December 2003) “deserves a place in the library of every university and college where renewable energy is taught.” (The International Journal of Electrical Engineering Education, Vol.41, No.2 April 2004) “a very comprehensive and well-organized treatment of the current status of wind power.” (Choice, Vol. 40, No. 4, December 2002) |
| sliding filament theory summary: Concepts of Biology Samantha Fowler, Rebecca Roush, James Wise, 2023-05-12 Black & white print. Concepts of Biology is designed for the typical introductory biology course for nonmajors, covering standard scope and sequence requirements. The text includes interesting applications and conveys the major themes of biology, with content that is meaningful and easy to understand. The book is designed to demonstrate biology concepts and to promote scientific literacy. |
| sliding filament theory summary: Stretch Intensity and the Inflammatory Response: A Paradigm Shift Nikos C. Apostolopoulos, 2018-12-27 In this manuscript, practitioners and students who are concerned with sports and rehabilitation medicine, kinesiology, as well as coaches and athletes, are introduced to numerous concepts, including mechanotransduction, inflammation, pro- and anti-inflammatory cytokines, calpains, the extracellular matrix, neutrophils and macrophages, and their relevance to stretching, particularly stretching intensity. Although the quantitative parameters of training, duration, and frequency are important, it is the qualitative criterion of intensity (“how much”) that the author suggests is ultimately of greater concern. Intensity, the rate and magnitude of force, may be responsible for the proper recovery, regeneration, and adaptation of the musculoskeletal tissues from training, competition, or rehabilitation from injuries. Research suggests that too much force results in the stimulation of an inflammatory response, one associated with a biochemical feedback emerging from a mechanical stimulus. The intent of this manuscript is twofold: to initiate the discussion of the importance of stretching intensity with regard to proper recovery, regeneration, and adaptation, and to suggest that researchers need to explore its potential role in addressing numerous inflammatory (RA) and non-inflammatory (OA, recurrent tendinitis etc.) musculoskeletal conditions as well. |
| sliding filament theory summary: Training for Speed and Endurance Peter Reaburn, David Jenkins, 1996 Authoritative yet accessible coverage of an area of growing importance. |
| sliding filament theory summary: Molecular Biology of the Cell , 2002 |
| sliding filament theory summary: Actin-based Motility Marie-France Carlier, 2010-09-23 Since the discovery of actin by Straub in the 1950’s and the pioneering work of Oosawa on actin self-assembly in helical laments in the 1960’s, many books and conference proceedings have been published. As one of the most essential p- teins in life, essential for movement in organisms rangingfrom bacteria to higher eukaryotes, it is no surprise that actin has fascinated generations of scientists from many different elds. Actin can be considered as a “living treasure” of biology; the kinetics and thermodynamics of self-assembly, the dissipative nature of actin po- merization, the molecular interactions of monomeric and polymerized actin with regulators, the mechanical properties of actin gels, and more recently the force p- ducing motile and morphogenetic processes organized by the actin nanomachine in response to signaling, are all milestones in actin research. Discoveries that directly derive from and provide deeper insight into the fundamental properties of actin are constantly being made, making actin an ever appealing research molecule. At the same time, the explosion in new technologies and techniques in biological sciences has served to attract researchers from an expanding number of disciplines, to study actin. This book presents the latest developments of these new multiscale approaches of force and movement powered by self-assembly processes, with the hope to opening our perspectives on the many areas of actin-based motility research. |
| sliding filament theory summary: An Introduction to Biomechanics Jay D. Humphrey, Sherry DeLange, 2013-11-11 Designed to meet the needs of undergraduate students, Introduction to Biomechanics takes the fresh approach of combining the viewpoints of both a well-respected teacher and a successful student. With an eye toward practicality without loss of depth of instruction, this book seeks to explain the fundamental concepts of biomechanics. With the accompanying web site providing models, sample problems, review questions and more, Introduction to Biomechanics provides students with the full range of instructional material for this complex and dynamic field. |
| sliding filament theory summary: Software-Defined Radio for Engineers Alexander M. Wyglinski, Robin Getz, Travis Collins, Di Pu, 2018-04-30 Based on the popular Artech House classic, Digital Communication Systems Engineering with Software-Defined Radio, this book provides a practical approach to quickly learning the software-defined radio (SDR) concepts needed for work in the field. This up-to-date volume guides readers on how to quickly prototype wireless designs using SDR for real-world testing and experimentation. This book explores advanced wireless communication techniques such as OFDM, LTE, WLA, and hardware targeting. Readers will gain an understanding of the core concepts behind wireless hardware, such as the radio frequency front-end, analog-to-digital and digital-to-analog converters, as well as various processing technologies. Moreover, this volume includes chapters on timing estimation, matched filtering, frame synchronization message decoding, and source coding. The orthogonal frequency division multiplexing is explained and details about HDL code generation and deployment are provided. The book concludes with coverage of the WLAN toolbox with OFDM beacon reception and the LTE toolbox with downlink reception. Multiple case studies are provided throughout the book. Both MATLAB and Simulink source code are included to assist readers with their projects in the field. |
| sliding filament theory summary: Introduction to Sports Biomechanics Roger Bartlett, 2002-04-12 Introduction to Sports Biomechanics has been developed to introduce you to the core topics covered in the first two years of your degree. It will give you a sound grounding in both the theoretical and practical aspects of the subject. Part One covers the anatomical and mechanical foundations of biomechanics and Part Two concentrates on the measuring techniques which sports biomechanists use to study the movements of the sports performer. In addition, the book is highly illustrated with line drawings and photographs which help to reinforce explanations and examples. |
| sliding filament theory summary: Heart Failure in the Child and Young Adult Joseph Rossano, John Lynn Jefferies, Anthony C Chang, Jeffrey A. Towbin, Robert E Shaddy, 2017-12-05 Heart Failure in the Child and Young Adult: From Bench to Bedside combines multiple etiologies for pediatric heart failure, including congenital heart disease, cardiomyopathies, infectious diseases and metabolic abnormalities. This comprehensive resource combines research from multiple contributors with current guidelines to bridge the knowledge gap for the recognition and management of heart failure in children. Coverage begins with the basic science of heart failure, then progresses through diagnosis, management, treatment and surgery, finally concluding with advanced special topics, including genetics, self-management and nanomedicine. - Provides coverage of the basic science of heart failure, its epidemiology and economic aspects, outpatient and inpatient management, and advanced therapies, including mechanical circulatory support and heart transplantation - Combines cutting-edge research with current guidelines from the field |
| sliding filament theory summary: Meiosis and Gametogenesis , 1997-11-24 In spite of the fact that the process of meiosis is fundamental to inheritance, surprisingly little is understood about how it actually occurs. There has recently been a flurry of research activity in this area and this volume summarizes the advances coming from this work. All authors are recognized and respected research scientists at the forefront of research in meiosis. Of particular interest is the emphasis in this volume on meiosis in the context of gametogenesis in higher eukaryotic organisms, backed up by chapters on meiotic mechanisms in other model organisms. The focus is on modern molecular and cytological techniques and how these have elucidated fundamental mechanisms of meiosis. Authors provide easy access to the literature for those who want to pursue topics in greater depth, but reviews are comprehensive so that this book may become a standard reference.Key Features* Comprehensive reviews that, taken together, provide up-to-date coverage of a rapidly moving field* Features new and unpublished information* Integrates research in diverse organisms to present an overview of common threads in mechanisms of meiosis* Includes thoughtful consideration of areas for future investigation |
| sliding filament theory summary: CSCS Study Guide Cscs Certification Prep Team, 2017-01-26 This guide covers quick overview, test-taking strategies, introductions to the CSCS exam, exercise sciences, nutrition, exercise technique, program design organization and administration, practice questions, detailed answer explanations. |
| sliding filament theory summary: Biomechanics of Human Motion Ph D Arus, Taylor & Francis Group, 2021-12-13 This book covers the general laws governing human biomechanics through an extensive review of martial arts techniques and references to fundamental theory. |
| sliding filament theory summary: Cells, Gels and the Engines of Life Gerald H. Pollack, 2001 An award-winning book that challenges the current wisdom of how cells work in a visionary, provocative, and accessible way... reads like a detective story. This highly praised book emphasises the role of cell water and the gel-like nature of the cell, building on these features to explore the mechanisms of communication, transport, contraction, division, and other essential cell functions. Lucidly written for the non-expert, the book is profound enough for biologists, chemists, physicists and engineers to devour. |
| sliding filament theory summary: Biomechanical Basis of Human Movement Joseph Hamill, Kathleen Knutzen, Timothy R. Derrick, 2015 Focusing on the quantitative nature of biomechanics, this book integrates current literature, meaningful numerical examples, relevant applications, hands-on exercises, and functional anatomy, physics, calculus, and physiology to help students - regardless of their mathematical background - understand the full continuum of human movement potential. |
| sliding filament theory summary: Physiology of Sport and Exercise W. Larry Kenney, Jack H. Wilmore, David L. Costill, 2012-01 Physiology of Sport and Exercise, Fifth Edition,offers comprehensive coverage of the relationship between human physiology and exercise. Updated in both content and design, this edition features revamped artwork that better illustrates how the body performs and responds to physical activity. |
| sliding filament theory summary: Engineering Physiology Karl H. E. Kroemer, Hiltrud J. Kroemer, Katrin E. Kroemer-Elbert, 2020-07-08 This fifth edition of “Engineering Physiology” has the same purpose as the earlier prints: to provide physiological information which engineers, designers, supervisors, managers and other planners need to make work and equipment “fit the human.” Chapters have been revised, figures and tables updated. New material discusses, among other topics, models of the human body that provide practical and design-oriented information, biomechanics describing the body’s capabilities and limitations, effects of shift work / sleep loss on attitude and performance, and new techniques to measure body sizes and the resultant changes in applications of that information. The book does not replace standard (biological-medical-chemical) textbooks on human physiology; instead, it provides information on human features and functions which are basic to ergonomics or human (factors) engineering, terms often used interchangeably. It helps lay the foundations for teamwork among engineers and physiologists, biologists and physicians. Bioengineering topics concern bones and tissues, neural networks, biochemical processes, bio- and anthromechanics, biosensors, perception of information and related actions, to mention just a few areas of common interest. Such understanding provides the underpinnings for devising work tasks, tools, workplaces, vehicles, work-rest schedules, human-machine systems, homes and designed environments so that we humans can work and live safely, efficiently and comfortably. |
| sliding filament theory summary: Continuum Modeling in Mechanobiology Larry A. Taber, 2020-06-15 This book examines key theoretical tools that are currently used to develop mathematical models as an aid in understanding the biological response of cells and tissues to mechanical stimuli. Problems in growth and remodeling, tissue and organ development, and functional adaptation are all covered. Chapters on tensor analysis and nonlinear elasticity provide the necessary background for understanding the engineering theories that are currently used to solve challenges in mechanobiology. This is an ideal book for biomechanical engineers who work on problems in mechanobiology and tissue engineering. |
| sliding filament theory summary: Physics of Cancer Claudia Tanja Mierke, 2018 In order to increase the healing opportunities of cancer, it is important to impair the dissemination and the spreading of cancer cells from the initial tumor and the formation of metastases in other organs or tissues of the human body. The underlying physical principles of these oncological processes are a major constituent of the research field highlighted in Physics of Cancer. This revised second edition is improved linguistically with multiple increases of the number of figures and the inclusion of several novel chapters such as actin filaments during matrix invasion, microtubuli during migration and matrix invasion, nuclear deformability during migration and matrix invasion, and the active role of the tumor stroma in regulating cell invasion -- Prové de l'editor. |
| sliding filament theory summary: Handbook of Human Motion , 2018-04-24 The Handbook of Human Motion is a large cross-disciplinary reference work which covers the many interlinked facets of the science and technology of human motion and its measurement. Individual chapters cover fundamental principles and technological developments, the state-of-the-art and consider applications across four broad and interconnected fields; medicine, sport, forensics and animation. The huge strides in technological advancement made over the past century make it possible to measure motion with unprecedented precision, but also lead to new challenges. This work introduces the many different approaches and systems used in motion capture, including IR and ultrasound, mechanical systems and video, plus some emerging techniques. The large variety of techniques used for the study of motion science in medicine can make analysis a complicated process, but extremely effective for the treatment of the patient when well utilised. The handbook descri bes how motion capture techniques are applied in medicine, and shows how the resulting analysis can help in diagnosis and treatment. A closely related field, sports science involves a combination of in-depth medical knowledge and detailed understanding of performance and training techniques, and motion capture can play an extremely important role in linking these disciplines. The handbook considers which technologies are most appropriate in specific circumstances, how they are applied and how this can help prevent injury and improve sporting performance. The application of motion capture in forensic science and security is reviewed, with chapters dedicated to specific areas including employment law, injury analysis, criminal activity and motion/facial recognition. And in the final area of application, the book describes how novel motion capture techniques have been designed specifically to aid the creation of increasingly realistic animation within films and v ideo games, with Lord of the Rings and Avatar just two examples. Chapters will provide an overview of the bespoke motion capture techniques developed for animation, how these have influenced advances in film and game design, and the links to behavioural studies, both in humans and in robotics. Comprising a cross-referenced compendium of different techniques and applications across a broad field, the Handbook of Human Motion provides the reader with a detailed reference and simultaneously a source of inspiration for future work. The book will be of use to students, researchers, engineers and others working in any field relevant to human motion capture. |
| sliding filament theory summary: Machina Carnis Dorothy M. Needham, 1971-11-30 This book is an account of the centuries of experiment and speculation that have led to our understanding of how muscles work. |
| sliding filament theory summary: Smooth Muscle Excitation T. B. Bolton, T. Tomita, 1996 This book is a compendium of the latest electrophysiological research on smooth muscles from an international collection of authors. It includes recent discoveries in calcium stores and their relationship to contraction and to electrical changes in the membrane. A major section of the book concentrates on calcium release mechanisms in the cell, their control, and the consequences of calcium release in the cell for membrane events. Smooth Muscle Excitation also covers the effects of chemicals released from adjacent cells. Key Features * State-of-the-art volume that represents a synopsis of all work currently being undertaken in this area throughout the world * Content covers both basic and clinical research * Provides a range of drug development studies * Presents contributions from many internationally recognized smooth muscle physiologists |
| sliding filament theory summary: Human Physiology Dee Unglaub Silverthorn, 2013-07-23 This test broke ground with its thorough coverage of molecular physiology seamlessly integrated into a traditional homeostasis-based systems approach. This edition introduces a major reorganisation of the early chapters to provide the best foundation for the course and new art features that streamline review and essential topics so that students can access them more easily on an as-needed basis. |
| sliding filament theory summary: Core Topics in Cardiac Anesthesia Jonathan H. Mackay, Joseph E. Arrowsmith, 2012-03-15 Since the publication of the first edition of Core Topics in Cardiac Anaesthesia, the clinical landscape has undergone significant change. Recent developments include the increased use of electrophysiology, the resurgence of primary percutaneous intervention in acute coronary syndromes, the use of percutaneous devices in patients previously considered inoperable, and the withdrawal of aprotinin. Against this landscape, this invaluable resource has been fully updated. New chapters are dedicated to right heart valves, pulmonary vascular disease, cardiac tumours and cardiac trauma. All other chapters have been updated according to the latest international guidelines. Written and edited by an international author team with a wealth of expertise in all aspects of the perioperative care of cardiac patients, topics are presented in an easy to digest and a readily accessible manner. Core Topics in Cardiac Anaesthesia, Second Edition is essential reading for residents and fellows in anaesthesia and cardiac surgery and clinical perfusionists. |
| sliding filament theory summary: Exercise Physiology Stanley P. Brown, Wayne C. Miller, Jane M. Eason, 2006 Bridging the gap between exercise physiology principles and clinical practice, this text provides comprehensive coverage of both traditional basic science and clinical exercise physiology principles. The book presents clinical applications and examples that connect theory to practice. More than 500 full-color illustrations and numerous graphs and tables complement the text. Reader-friendly features including Perspective Boxes, Research Highlights, Biography Boxes, and Case Studies engage readers and reinforce key concepts. A bonus three-dimensional interactive anatomy CD-ROM from Primal Pictures and a Student Resource CD-ROM accompany the book. LiveAdvise online faculty support and student tutoring services are available free with the text. |
| sliding filament theory summary: Biomechanics and Gait Analysis Nicholas Stergiou, 2020-03-25 Biomechanics and Gait Analysis presents a comprehensive book on biomechanics that focuses on gait analysis. It is written primarily for biomedical engineering students, professionals and biomechanists with a strong emphasis on medical devices and assistive technology, but is also of interest to clinicians and physiologists. It allows novice readers to acquire the basics of gait analysis, while also helping expert readers update their knowledge. The book covers the most up-to-date acquisition and computational methods and advances in the field. Key topics include muscle mechanics and modeling, motor control and coordination, and measurements and assessments. This is the go to resource for an understanding of fundamental concepts and how to collect, analyze and interpret data for research, industry, clinical and sport. - Details the fundamental issues leading to the biomechanical analyses of gait and posture - Covers the theoretical basis and practical aspects associated with gait analysis - Presents methods and tools used in the field, including electromyography, signal processing and spectral analysis, amongst others |
| sliding filament theory summary: Clinical Application of Neuromuscular Techniques: The upper body Leon Chaitow, Judith DeLany, 2008-01-01 Discusses theories and physiology relevant to the manual treatment of chronic pain, especially as it regards the soft tissues of the upper body. Includes step-by-step protocols that address each muscle of a region and a regional approach to treatment, and gives a structural review of each region, including ligaments and functional anatomy. |
| sliding filament theory summary: AS Level Textbook John Honeybourne, Michael Hill, Helen Moors, 2000 The second edition of this well-established text has been updated to match the revised course specifications for OCR, AQA and Edexcel syllabuses. |
SLIDING | definition in the Cambridge English Dictionary
When he's turning a double play and jumping over a guy sliding into second, he could include it. Those who can pay are charged on a sliding scale, from $5 to $30. The child and dependent …
SLIDING Definition & Meaning - Merriam-Webster
The meaning of SLIDE is to move smoothly along a surface : slip. How to use slide in a sentence.
SLIDING Definition & Meaning | Dictionary.com
Sliding definition: rising or falling, increasing or decreasing, according to a standard or to a set of conditions.. See examples of SLIDING used in a sentence.
Sliding - definition of sliding by The Free Dictionary
n. 1. A sliding movement or action. 2. a. A smooth, usually inclined surface or track for sliding: a water slide. b. A playground apparatus for children to slide on, typically consisting of a smooth …
Sliding - Definition, Meaning & Synonyms | Vocabulary.com
6 days ago · /ˈslaɪdɪŋ/ IPA guide Other forms: slidingly Definitions of sliding adjective being a smooth continuous motion synonyms:
SLIDING definition in American English | Collins English Dictionary
2 senses: 1. rising or falling in accordance with given specifications 2. regulated or moved by sliding.... Click for more definitions.
sliding - WordReference.com Dictionary of English
to move along in continuous contact with a smooth or slippery surface: to slide down a snow-covered hill. to slip or skid. to glide or pass smoothly. to slip easily, quietly, or unobtrusively on …
slide verb - Definition, pictures, pronunciation and usage notes ...
Definition of slide verb from the Oxford Advanced Learner's Dictionary. [intransitive, transitive] to move easily over a smooth or wet surface; to make something move in this way. As I turned …
sliding - Wiktionary, the free dictionary
Mar 26, 2025 · sliding The act of making a slip or losing one's traction. (rare) Effortless or fluid movement. (rare) Dragging; moving something alongside oneself.
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SLIDING | definition in the Cambridge English Dictionary
When he's turning a double play and jumping over a guy sliding into second, he could include it. Those who can pay are charged on a sliding scale, from $5 to $30. The child and dependent …
SLIDING Definition & Meaning - Merriam-Webster
The meaning of SLIDE is to move smoothly along a surface : slip. How to use slide in a sentence.
SLIDING Definition & Meaning | Dictionary.com
Sliding definition: rising or falling, increasing or decreasing, according to a standard or to a set of conditions.. See examples of SLIDING used in a sentence.
Sliding - definition of sliding by The Free Dictionary
n. 1. A sliding movement or action. 2. a. A smooth, usually inclined surface or track for sliding: a water slide. b. A playground apparatus for children to slide on, typically consisting of a smooth …
Sliding - Definition, Meaning & Synonyms | Vocabulary.com
6 days ago · /ˈslaɪdɪŋ/ IPA guide Other forms: slidingly Definitions of sliding adjective being a smooth continuous motion synonyms:
SLIDING definition in American English | Collins English Dictionary
2 senses: 1. rising or falling in accordance with given specifications 2. regulated or moved by sliding.... Click for more definitions.
sliding - WordReference.com Dictionary of English
to move along in continuous contact with a smooth or slippery surface: to slide down a snow-covered hill. to slip or skid. to glide or pass smoothly. to slip easily, quietly, or unobtrusively on …
slide verb - Definition, pictures, pronunciation and usage notes ...
Definition of slide verb from the Oxford Advanced Learner's Dictionary. [intransitive, transitive] to move easily over a smooth or wet surface; to make something move in this way. As I turned …
sliding - Wiktionary, the free dictionary
Mar 26, 2025 · sliding The act of making a slip or losing one's traction. (rare) Effortless or fluid movement. (rare) Dragging; moving something alongside oneself.
Sliding Patio Door - Patio Doors - The Home Depot
Get free shipping on qualified Sliding Patio Door Patio Doors products or Buy Online Pick Up in Store today in the Doors & Windows Department.
