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| prof dick swaab: The Human Hypothalamus Dick F. Swaab, Ruud M. Buijs, Paul J. Lucassen, Ahmad Salehi, Felix Kreier, 2021-07-04 The Human Hypothalamus: Neuroendocrine Disorders, Volume 181 in the Handbook of Clinical Neurology series, provides comprehensive summaries of recent research on the brain and nervous system as they relate to clinical neurology. This volume summarizes the role of the hypothalamus in neuroendocrine disorders, identifying the mechanism of action, disorder etiology, and best practices for assessment and treatment. Disorders covered include pituitary hypothalamic disorders of development and growth, hypothalamic tumor related disorders, hypothalamic autoimmune disorders and infection, disorders of vasopressin, water and sodium homeostasis, eating disorders, and gonadotropic hormone regulation disorders. - Discusses the importance of the hypothalamus in human growth and development - Reviews hypothalamic related tumors, as well as pituitary, autoimmune, vasopressin and hormone regulation disorders - Includes metabolic and eating disorders - Identifies mechanisms of disease action and etiology - Provides best practice information for assessment and treatment |
| prof dick swaab: We Are Our Brains D. F. Swaab, 2014-01-07 A vivid account of what makes us human. Based groundbreaking new research, We Are Our Brains is a sweeping biography of the human brain, from infancy to adulthood to old age. Renowned neuroscientist D. F. Swaab takes us on a guided tour of the intricate inner workings that determine our potential, our limitations, and our desires, with each chapter serving as an eye-opening window on a different stage of brain development: the gender differences that develop in the embryonic brain, what goes on in the heads of adolescents, how parenthood permanently changes the brain. Moving beyond pure biological understanding, Swaab presents a controversial and multilayered ethical argument surrounding the brain. Far from possessing true free will, Swaab argues, we have very little control over our everyday decisions, or who we will become, because our brains predetermine everything about us, long before we are born, from our moral character to our religious leanings to whom we fall in love with. And he challenges many of our prevailing assumptions about what makes us human, decoding the intricate “moral networks” that allow us to experience emotion, revealing maternal instinct to be the result of hormonal changes in the pregnant brain, and exploring the way that religious “imprinting” shapes the brain during childhood. Rife with memorable case studies, We Are Our Brains is already a bestselling international phenomenon. It aims to demystify the chemical and genetic workings of our most mysterious organ, in the process helping us to see who we are through an entirely new lens. Did you know? • The father’s brain is affected in pregnancy as well as the mother’s. • The withdrawal symptoms we experience at the end of a love affair mirror chemical addiction. • Growing up bilingual reduces the likelihood of Alzheimer’s. • Parental religion is imprinted on our brains during early development, much as our native language is. Praise for We Are Our Brains “Swaab’s ‘neurobiography’ is witty, opinionated, passionate, and, above all, cerebral.”—Booklist (starred review) “A fascinating survey . . . Swaab employs both personal and scientific observation in near-equal measure.”—Publishers Weekly (starred review) “A cogent, provocative account of how twenty-first-century ‘neuroculture’ has the potential to effect profound medical and social change.”—Kirkus Reviews |
| prof dick swaab: Photographic Treatment © Laurence Aëgerter, 2017 Photographic Treatment consists of a series of five books, Daily Photo Dose 1, 2, 3, 4 and 5, each with thirty black and white photographic diptychs collected and edited by Laurence Aegerter. Conducted in collaboration with neurologists, gerontologists and psychologists, the project aims to provide an image-based therapeutic tool to improve the well-being of senile dementia patients. |
| prof dick swaab: The End of Gender Debra Soh, 2021-08-31 International sex researcher, neuroscientist, and frequent contributor to The Globe and Mail (Toronto) Debra Soh [discusses what she sees as] gender myths in this ... examination of the many facets of gender identity-- |
| prof dick swaab: Woman Enough Kristen Worley, Johanna Schneller, 2019-03-26 A powerful and inspiring story of self-realization and legal victory that upends our basic assumptions about sexual identity. In 1966, a male baby, Chris, was adopted by an upper-middle-class Toronto couple. From early childhood, Chris felt ill-at-ease as a boy and like an outsider in his conservative family. An obsession with sports--running, waterskiing and especially cycling--helped him survive what he would eventually understand to be a profound disconnect between his anatomical sexual identity and his gender identity. In his twenties, with the support of newfound friends and family and the medical community, Chris became Kristen. Chris had been a world-class cyclist, and now Kristen wanted to compete for her country and herself in the 2008 Beijing Olympics. She became the first athlete in the world to submit to the International Olympic Committee's gender verification process, the Stockholm Consensus. An all-male jury determined she fit their biological criteria--but the IOC ultimately objected to her use of testosterone supplements. They, and other sports bodies, regard them as performance enhancing, when in fact all transitioned female athletes need the hormone to stay healthy and to compete. So Kristen filed a complaint against the sports bodies standing in her way with the Ontario Human Rights Tribunal. And she won. Woman Enough is the account of a human rights battle with global repercussions for the world of sport; it's a challenge to rethink fixed ideas about gender; and it's the extraordinary story of a boy who was rejected for who he wasn't, and who fought back until she found out who she is. |
| prof dick swaab: Circadian Clocks: Role in Health and Disease Michelle L. Gumz, 2016-02-29 This book sheds new light on the molecular mechanisms that generate circadian rhythms. It examines how biological rhythms influence physiological processes such as sleep, hormone synthesis and secretion, immunity, kidney function, the cardiovascular system, blood pressure, and the digestive system. Clinical implications are considered while exploring the impact of rhythms on neuropsychiatric disorders and chronotherapy’s potential for reducing cardiovascular risk. Offering a cross-section of expertise in both basic and translational (bench-to-bedside) research, this book serves as a guide for physicians and scientists who wish to learn more about the impact of circadian rhythms on physiological processes in health and disease. |
| prof dick swaab: Autonomic Nervous System Ruud M. Buijs, Dick F. Swaab, 2013-11-11 Autonomic Nervous System provides an introduction to the latest science and detailed chapters on advances in the clinical diagnosis and treatment of autonomic system disorders. The autonomic nervous system controls all involuntary actions within the human nervous system. Core body functions regulated by the autonomic system include breathing, heartbeat, blood pressure, body temperature, perspiration, and bowel, bladder and sexual function. Our understanding of the neurotransmitters associated with the autonomic nervous system has expanded over the past 15 years associated with current research efforts and are now impacting the diagnosis and treatment of autonomic nervous system disorders by clinical neurologists. This volume is a valuable companion for neuroscience and clinical neurology researchers and practitioners. - A volume in the Handbook of Clinical Neurology series, which has an unparalleled reputation as the world's most comprehensive source of information in neurology - International list of contributors, including the leading workers in the field - Describes the advances that have occurred in clinical neurology and the neurosciences and their impact on the understanding of neurological disorders and on patient care |
| prof dick swaab: Innate Kevin J. Mitchell, 2018-10-16 A leading neuroscientist explains why your personal traits are more innate than you think What makes you the way you are—and what makes each of us different from everyone else? In Innate, leading neuroscientist and popular science blogger Kevin Mitchell traces human diversity and individual differences to their deepest level: in the wiring of our brains. Deftly guiding us through important new research, including his own groundbreaking work, he explains how variations in the way our brains develop before birth strongly influence our psychology and behavior throughout our lives, shaping our personality, intelligence, sexuality, and even the way we perceive the world. We all share a genetic program for making a human brain, and the program for making a brain like yours is specifically encoded in your DNA. But, as Mitchell explains, the way that program plays out is affected by random processes of development that manifest uniquely in each person, even identical twins. The key insight of Innate is that the combination of these developmental and genetic variations creates innate differences in how our brains are wired—differences that impact all aspects of our psychology—and this insight promises to transform the way we see the interplay of nature and nurture. Innate also explores the genetic and neural underpinnings of disorders such as autism, schizophrenia, and epilepsy, and how our understanding of these conditions is being revolutionized. In addition, the book examines the social and ethical implications of these ideas and of new technologies that may soon offer the means to predict or manipulate human traits. Compelling and original, Innate will change the way you think about why and how we are who we are. |
| prof dick swaab: What About Me? Paul Verhaeghe, 2014-03-31 According to current thinking, anyone who fails to succeed must have something wrong with them. The pressure to achieve and be happy is taking a heavy toll, resulting in a warped view of the self, disorientation, and despair. People are lonelier than ever before. Today’s pay-for-performance mentality is turning institutions such as schools, universities, and hospitals into businesses, while individuals are being made to think of themselves as one-person enterprises. Love is increasingly hard to find, and we struggle to lead meaningful lives. In What about Me?, Paul Verhaeghe’s main concern is how social change has led to this psychic crisis and altered the way we think about ourselves. He investigates the effects of thirty years’ acceptance of neo-liberalism, free-market forces, and privatisation, and the resulting relationship between our engineered society and individual identity. It turns out that who we are is, as always, determined by the context in which we live. From his clinical experience as a psychotherapist, Verhaeghe shows the profound impact that social change is having on mental health, even to the extent of affecting the nature of the disorders from which we suffer. But his book ends on a note of cautious optimism. We can once again become masters of our fate — if we accept the challenge. |
| prof dick swaab: Our Ageing Brain Andre Aleman, 2014-09-11 An international bestseller delivering good news on brain function and ageing We all worry sometimes that our brains — particularly our memories — just don’t work as well as they used to. In this illuminating book, internationally acclaimed Dutch neuroscientist André Aleman shows that although the decline in our mental capacities begins earlier than we think, this is not such a bad thing. In fact, older people are more resistant to the effects of stress, cope better with their emotions and with complex situations, and are — generally speaking — happier than their younger counterparts. Our Ageing Brain will change the way we think about age and mental acuity. Drawn from the latest research in cognitive science, it outlines what takes place in the brain as we age, how to recognise the early symptoms of Alzheimer’s disease, and how to distinguish fact from fiction when it comes to ways of slowing down the ageing process. It concludes with the seven most important things we can each do to keep our brains healthy. Published here in English for the first time, this is a refreshing, informative, and ultimately reassuring examination of what happens to our most important organ as we grow older. PRAISE FOR ANDRÉ ALEMAN ‘[A] remarkably cheerful book, full of facts revealed by new research, positive anecdotes about astonishing wrinklies, and some very good life-style advice.’ The Cooma-Monaro Express ‘A book you can't put down, no matter how old you are.’ Psychologie Magazine |
| prof dick swaab: Religion and Psychiatry Peter Verhagen, Herman M. Van Praag, Juan José Lopez-Ibor, John Cox, Driss Moussaoui, 2012-02-27 Religion (and spirituality) is very much alive and shapes the cultural values and aspirations of psychiatrist and patient alike, as does the choice of not identifying with a particular faith. Patients bring their beliefs and convictions into the doctor-patient relationship. The challenge for mental health professionals, whatever their own world view, is to develop and refine their vocabularies such that they truly understand what is communicated to them by their patients. Religion and Psychiatry provides psychiatrists with a framework for this understanding and highlights the importance of religion and spirituality in mental well-being. This book aims to inform and explain, as well as to be thought provoking and even controversial. Patiently and thoroughly, the authors consider why and how, when and where religion (and spirituality) are at stake in the life of psychiatric patients. The interface between psychiatry and religion is explored at different levels, varying from daily clinical practice to conceptual fieldwork. The book covers phenomenology, epidemiology, research data, explanatory models and theories. It also reviews the development of DSM V and its awareness of the importance of religion and spirituality in mental health. What can religious traditions learn from each other to assist the patient? Religion and Psychiatry discusses this, as well as the neurological basis of religious experiences. It describes training programmes that successfully incorporate aspects of religion and demonstrates how different religious and spiritual traditions can be brought together to improve psychiatric training and daily practice. Describes the relationship of the main world religions with psychiatry Considers training, policy and service delivery Provides powerful support for more effective partnerships between psychiatry and religion in day to day clinical care This is the first time that so many psychiatrists, psychologists and theologians from all parts of the world and from so many different religious and spiritual backgrounds have worked together to produce a book like this one. In that sense, it truly is a World Psychiatric Association publication. Religion and Psychiatry is recommended reading for residents in psychiatry, postgraduates in theology, psychology and psychology of religion, researchers in psychiatric epidemiology and trans-cultural psychiatry, as well as professionals in theology, psychiatry and psychology of religion |
| prof dick swaab: The Power of Hormones Max Nieuwdorp, 2024-07-30 Decode the subtle signals of hormones with this foundational book from expert endocrinologist and leading researcher in the field. Hormones rule our lives. From conception, to birth, to our last breath, hormones control the delicate processes that keep our bodies in balance. However, when this careful stasis is disturbed, our hormones can wreak havoc on our health. Max Nieuwdorp, MD, PhD, knows exactly what signals your hormones are sending you and how they impact how you look, feel, and behave. In this foundational guide to hormonal health, he breaks down how hormones impact every system in the body, empowering you with the knowledge you need to get to the root of chronic health problems and set yourself up long lasting, sustainable wellness. Inspired by Dr. Nieuwdorp’s day-to-day interaction with his patients, The Power of Hormones describes hormonal health in a detailed and accessible style, helping you clue in to symptoms of hormonal imbalance such as persistent fatigue and weight gain. His unique approach advocates for considering the far-reaching roles played by hormones throughout the body and is a go-to guide for understanding how they influence our health, our lives, and who we are. |
| prof dick swaab: The Human Hypothalamus Dick F. Swaab, Felix Kreier, Paul J. Lucassen, Ahmad Salehi, Ruud M. Buijs, 2021-06-15 The Hypothalamus is an important area of the brain for understanding a variety of neurological disorders. This volume summarizes for readers the anatomy and physiology of the anterior hypothalamus, to better understand pathology and treatment of hypothalamus related disorders. In addition to anatomy and physiology in humans, cytoarchitecture and chemoarchitecture in rodents is provided. The volume explores the role of the hypothalamus in disorders of eating, sleeping, anxiety, and mood, as well as its role in sexual behavior and gender identity. Coverage includes how Parkinson's, Alzheimer's and other neurological disorders relate to the hypothalamus. - Reviews the anatomy and physiology of the anterior hypothalamus - Provides cytoarchitecture and chemoarchitecture from rodents - Discusses hypothalamic related disorders of eating, sleeping, anxiety, and mood - Covers how Parkinson's, Alzheimer's and other neurological disorders relate to the hypothalamus - Explores the role of the hypothalamus in sexual behavior and gender identity |
| prof dick swaab: Life Before Birth: the Challenges of Fetal Development (Second Edition) Peter W. Nathanielsz, 2021-04 We pass more biological milestones before birth than any other time in our lives. Peter W. Nathanielsz writes that how we develop in the womb is the most fascinating biological story, central to our life-time health. The first edition of Life Before Birth, published in twelve languages, was the first evidence-based book on the science of fetal development, easily accessible for the general reader. This unique book unlocks the awe-inspiring biology that unfolds as fetuses live and grow in one environment, the womb, while simultaneously preparing for independent life in a very different previously unexperienced world. The new edition shows how the placenta functions as a fetal lung, gut, kidney and multiple glands. Just as training prepares a track athlete, fetal preparations determine performance when the great event of birth occurs. The development of a unique fetal blood system that changes within minutes when the placenta is lost at birth is a truly dramatic story. |
| prof dick swaab: The Male Brain Louann Brizendine, MD, 2011-01-25 From the author of the groundbreaking New York Times bestseller The Female Brain, here is the eagerly awaited follow-up book that demystifies the puzzling male brain. Dr. Louann Brizendine, the founder of the first clinic in the country to study gender differences in brain, behavior, and hormones, turns her attention to the male brain, showing how, through every phase of life, the male reality is fundamentally different from the female one. Exploring the latest breakthroughs in male psychology and neurology with her trademark accessibility and candor, she reveals that the male brain: -is a lean, mean, problem-solving machine. Faced with a personal problem, a man will use his analytical brain structures, not his emotional ones, to find a solution. -thrives under competition, instinctively plays rough and is obsessed with rank and hierarchy. -has an area for sexual pursuit that is 2.5 times larger than the female brain, consuming him with sexual fantasies about female body parts. -experiences such a massive increase in testosterone at puberty that he perceive others' faces to be more aggressive. The Male Brain finally overturns the stereotypes. Impeccably researched and at the cutting edge of scientific knowledge, this is a book that every man, and especially every woman bedeviled by a man, will need to own. |
| prof dick swaab: Race, Monogamy, and Other Lies They Told You Agustín Fuentes, 2015-05 There are three major myths of human nature: humans are divided into biological races; humans are naturally aggressive; and men and women are truly different in behavior, desires, and wiring. In an engaging and wide-ranging narrative, Agustín Fuentes counters these pervasive and pernicious myths about human behavior. Tackling misconceptions about what race, aggression, and sex really mean for humans, Fuentes incorporates an accessible understanding of culture, genetics, and evolution, requiring us to dispose of notions of “nature or nurture.” Presenting scientific evidence from diverse fields—including anthropology, biology, and psychology—Fuentes devises a myth-busting toolkit to dismantle persistent fallacies about the validity of biological races, the innateness of aggression and violence, and the nature of monogamy and differences between the sexes. A final chapter plus an appendix provide a set of take-home points on how readers can myth-bust on their own. Accessible, compelling, and original, this book is a rich and nuanced account of how nature, culture, experience, and choice interact to influence human behavior. |
| prof dick swaab: Fluid Balance, Hydration, and Athletic Performance Flavia Meyer, Zbigniew Szygula, Boguslaw Wilk, 2016-01-06 Athletes and nonathletes frequently consume too little water or fluids, affecting exercise performance as well as overall health. This book comprehensively reviews the aspects relating to body fluid balance, rehydration, and physical exercise. It provides background on body water balance and turnover, topics related to electrolyte balance, and sweating as the basis for thermoregulatory and fluid homeostasis during exercise. In addition, chapters cover body water balance evaluation and regulation; cardiovascular and metabolic responses to fluid imbalance; effects of dehydration on aerobic power, muscle strength, and cognitive function; fluid intake timing; and optimal beverage selection. |
| prof dick swaab: The Human Hypothalamus Dick F. Swaab, Ruud M. Buijs, Felix Kreier, Paul J. Lucassen, Ahmad Salehi, 2021-07-07 The Human Hypothalamus: Neuropsychiatric Disorders, Volume 181 in the Handbook of Clinical Neurology series, provides comprehensive summaries of recent research on the brain and nervous system as they relate to clinical neurology. This volume identifies the neurobiology and neurophysiology of disorders relating to the hypothalamus and provides treatment information for these disorders. Disorders covered include neuropsychiatric, neurodegenerative, periodic, and autoimmune disorders. Coverage includes Alzheimer's, Parkinson's, epilepsy, sleep, pain, depression, anxiety, OCD, PTSD, schizophrenia, autism, aggressions, addiction, and more. - Summarizes research on how the hypothalamus relates to neurological disorders - Contains neuropsychiatric, neurodegenerative, periodic and autonomic disorders - Includes the neurobiology of, and treatment for, each disorder - Covers depression, anxiety, OCD, PTSD, schizophrenia, autism, aggression, addiction, and more - Provides coverage of sleep and pain |
| prof dick swaab: Into the Gray Zone Adrian Owen, 2017-06-20 In this “riveting read, meshing memoir with scientific explication” (Nature), a world-renowned neuroscientist reveals how he learned to communicate with patients in vegetative or “gray zone” states and, more importantly, he explains what those interactions tell us about the working of our own brains. “Vivid, emotional, and thought-provoking” (Publishers Weekly), Into the Gray Zone takes readers to the edge of a dazzling, humbling frontier in our understanding of the brain: the so-called “gray zone” between full consciousness and brain death. People in this middle place have sustained traumatic brain injuries or are the victims of stroke or degenerative diseases, such as Alzheimer’s and Parkinson’s. Many are oblivious to the outside world, and their doctors believe they are incapable of thought. But a sizeable number—as many as twenty percent—are experiencing something different: intact minds adrift deep within damaged brains and bodies. An expert in the field, Adrian Owen led a team that, in 2006, discovered this lost population and made medical history. Scientists, physicians, and philosophers have only just begun to grapple with the implications. Following Owen’s journey of exciting medical discovery, Into the Gray Zone asks some tough and terrifying questions, such as: What is life like for these patients? What can their families and friends do to help them? What are the ethical implications for religious organizations, politicians, the Right to Die movement, and even insurers? And perhaps most intriguing of all: in defining what a life worth living is, are we too concerned with the physical and not giving enough emphasis to the power of thought? What, truly, defines a satisfying life? “Strangely uplifting…the testimonies of people who have returned from the gray zone evoke the mysteries of consciousness and identity with tremendous power” (The New Yorker). This book is about the difference between a brain and a mind, a body and a person. Into the Gray Zone is “a fascinating memoir…reads like a thriller” (Mail on Sunday). |
| prof dick swaab: The Moral Conflict of Law and Neuroscience Peter A. Alces, 2018-01-18 New insights offered by neuroscience have provoked discussions of the nature of human agency and responsibility. Alces draws on neuroscience to explore the internal contradictions of legal doctrines, and consider what would be involved in constructing novel legal regimes based on emerging understandings of human capacities and characteristics not only in criminal law but in contract and tort law.--Provided by publisher. |
| prof dick swaab: How Intelligence Happens John Duncan, 2010-10-22 A lively journey through the brain’s inner workings from “one of the world’s leading cognitive neuroscientists” (The Wall Street Journal). Human intelligence builds sprawling cities, vast cornfields, and complex microchips. It takes us from the atom to the limits of the universe. How does the biological brain, a collection of billions of cells, enable us to do things no other species can do? In this book, neuroscientist John Duncan offers an adventure story—the story of the hunt for basic principles of human intelligence, behavior, and thought. Using results drawn from classical studies of intelligence testing; from attempts to build computers that think; from studies of how minds change after brain damage; from modern discoveries of brain imaging; and from groundbreaking recent research, he synthesizes often difficult-to-understand information into clear, fascinating prose about how brains work. Moving from the foundations of psychology, artificial intelligence, and neuroscience to the most current scientific thinking, How Intelligence Happens is “a timely, original, and highly readable contribution to our understanding” (Nancy Kanwisher, MIT) from a winner of the Heineken Prize for Cognitive Science |
| prof dick swaab: Autonomic Nervous System Ruud M. Buijs, Carolina Escobar, Dick F. Swaab, 2013-11-11 Our biological clock, the suprachiasmatic nucleus (SCN), sets the pace of our life: it provides a rhythmic function to our sleep–wake cycle. In order to do so properly the SCN synchronizes our physiology to behavioral patterns by directing the autonomic and hormonal output of the hypothalamus to the different organs of the body that require a different setting – activity or inactivity – during particular phases of the day or night. In this chapter we show that this delicate balance requires that the SCN should not only provide an output to these organs but also be informed about the physiological state of the organs in order to adapt its output. This occurs via a hypothalamic neuronal network that provides the necessary input to the SCN. We argue that the feedback that the SCN receives from its hypothalamic target structures is essential to maintain a balance in our physiological functions, which fluctuate during the sleep–wake cycle. We propose that this crucial role of the hypothalamus in the homeostatic response is the reason why, e.g., in aging or depression, changes in the functioning of the biological clock, the SCN, lead to the development of pathology. In addition, if this balance is not adequately organized, for example, if the signals of the biological clock are violated by being active and eating during the night, as in shift work, one will be more susceptible to diseases such as hypertension, obesity, diabetes, and metabolic syndrome. |
| prof dick swaab: Decision Making: Neural and Behavioural Approaches , 2013-01-10 This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields.This volume explores interdisciplinary research on decision making taking a neural and behavioural approach - Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research - Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered - All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist |
| prof dick swaab: Brain Machine Interfaces , 2011-08-21 This volume follows on from the symposium Brain Machine Interfaces - Implications for science, clinical practice and society, held on August 26th-29th 2010 in Ystad, Sweden, and features contributions from pioneers and leading scientists in the field of BMI and motor systems physiology, including spinal cord, basal ganglia and motor cortex. The wide range of topics covered include implants for mind control of prostheses and in robotics, clinical and experimental research on Deep Brain Stimulation (DBS) for the treatment of Parkinson's disease, depression and Alzheimer's disease, cochlear implants, retinal implants, novel flexible micro- and nano-electrode implants, safety aspects including acute and chronic tissue reactions to implants and on ethical issues in DBS. Program and abstracts from the individual contributors can be found on http://www.med.lu.se/nrc/bmi_symposium. - Leading authors review the state-of-the-art in their field of investigation and provide their views and perspectives for future research - Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered - All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist |
| prof dick swaab: Orexin/Hypocretin System Anantha Shekhar, 2012-09-05 In The Orexin/Hypocretin System: Physiology and Pathophysiology, leading researchers and clinicians set the stage for further research on the loss of orexin/hypocretin neurons in humans, regulation of sleep and wakefulness by the orexin/hypocretin system, and the role of the orexin/hypocretin system in many other physiological processes, including feeding, autonomic regulation, and neuroendocrine regulation. Topics of interest include an assessment of the functions and the physiology of orexin/hypocretin, its pathophysiology in human narcolepsy-cataplexy, and possible pharmacological treatments. The authors also introduce several experimental methods for orexin/hypocretin research, and, using multidisciplinary approaches, explain their uses and limitations. Authoritative and state-of-the-art, The Orexin/Hypocretin System: Physiology and Pathophysiology will aid scientists in the search for novel bioactive peptides and their receptors, as well as novel physiological insights and opportunities for the clinical treatment of not only narcolepsy, but also a broad range of diseases associated with endocrine, feeding and body weight regulation.--Résumé de l'éditeur. |
| prof dick swaab: Brain Extracellular Matrix in Health and Disease , 2014-10-30 In the central nervous system, extracellular matrix (ECM) molecules, including hyaluronic acid, chondroitin and heparan sulfate proteoglycans, tenascins, reelin and agrin, along with their remodelling enzymes, such as neurotrypsin, neuropsin, plasminogen activators, and metalloproteinases, are secreted by neural and non-neural cells into the extracellular space to form the ECM and signal via ECM receptors. Despite recent advances in the ECM field, the importance of neural ECM for physiological and pathological processes is currently less widely recognized than that of other CNS elements. This book will enlighten recent progress in our understanding of mechanisms by which neural ECM, its receptors and activity-dependent ECM remodeling regulate neural development, synaptic plasticity, and contribute to pathological changes in the brain. In the first part, the roles of ECM signaling and proteolytic modification of ECM in neurogenesis, neural migration, axonal pathfinding, synaptogenesis, synaptic and homeostatic plasticity will be discussed. The second part will focus on the emerging ECM-dependent mechanisms associated with CNS injury, epilepsy, neurodegenerative and neuropsychiatric diseases. For further development of neural ECM field, a very important contribution is the third part of the book, which is devoted to neural ECM-targeting tools and therapeutics. The concluding fourth part will highlight advances in development of artificial ECM and ECM-based systems suitable for multisite recording and stimulation of neural cells. - Authors are the leading experts in the field of brain extracellular matrix in health and disease - Book covers the most important aspects of brain extracellular matrix in health and disease - Interesting for both scientists and clinicians |
| prof dick swaab: Optogenetics Thomas Knopfel, Edward S. Boyden, 2012-04-19 Optogenetics is a fast-growing field concerning the invention, and use, of molecules that are genetically expressed in cells, and then either report on cellular physiology in optical form, or enable control of specific pathways in cells when actuated by light. This book reviews the current state, as well as the underlying principles and future directions, of a diversity of optogenetic tools of importance for observing and controlling cellular signaling and physiology. These tools are already revolutionizing neuroscience, and are starting to have impact on fields ranging from metabolism to development to cardiology. The book contains a dozen chapters written by world experts on these topics, half focusing on the optogenetic molecular tools themselves, and half on the genetic and hardware approaches that make them powerfully useful in intact tissues and organisms. Leading authors review the state-of-the-art in their field of investigation and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist |
| prof dick swaab: Saussure and Sechehaye: Myth and Genius Pieter Seuren, 2018-08-13 In this book, Pieter Seuren argues that Ferdinand de Saussure has been grossly overestimated over the past century, while his junior colleague Albert Sechehaye has been undeservedly ignored. Saussure was anything but the great innovator he is generally believed to be. Sechehaye was a genius providing many trenchant analyses and anticipating many modern insights. The lives and works of both men are discussed in detail and they are placed in the cultural, intellectual and social environment of their day. Much attention is paid to the theoretical issues involved, in particular to the notion and history of structuralism, to the great subject-predicate debate that dominated linguistic theory at the time, and to questions of methodology in the theory of language. |
| prof dick swaab: Doctor Ferdinand Peeters Karl van den Broeck, 2018 The story of doctor Ferdinand Peeters (1918-1998) and his role in the development of the pill has held Belgium in thrall for almost a decade. It is time to introduce the real father of the contraceptive pill to the rest of the world. After years of research, Belgian journalist Karl van den Broeck concluded that not the American Gregory Pincus was the inventor of the pill. His prototype had so many adverse effects that it wasn’t a viable option in the long term. It was the Belgian doctor Ferdinand Peeters who, in 1959-1960, created the first clinically applicable contraceptive pill: Anovlar. It was this pill that set the standard for all future pills to follow. Ferdinand – Nand – Peeters was a devout Catholic and during an audience with pope John XXIII, he urged that the church should sanction the use of the Pill. But when Paul VI decided in 1968 that birth control other than the practice of periodic abstinence would remain forbidden, doctor Peeters didn’t breathe a word about his role in the development of the pill. Even his family was barely aware of it. In The Real Father of the Pill, Karl van den Broeck tells the long hidden story behind this invention, a story of innovation and threats, of grateful women and papal ambivalence. With this book doctor Peeters is finally given the recognition he deserves. This book includes the documentary The Real Father of the Pill. More information can be found in the book. |
| prof dick swaab: Biophilia Edward O. WILSON, 2009-06-30 Biophilia is Edward O. Wilson's most personal book, an evocation of his own response to nature and an eloquent statement of the conservation ethic. Wilson argues that our natural affinity for life—biophilia—is the very essence of our humanity and binds us to all other living species. |
| prof dick swaab: Enhancing Performance for Action and Perception , 2011-07-16 This volume of Progess in Brain Research follows on from the 32nd International Symposium of the Groupe de recherche sur le système nerveux central (GRSNC), May 2010, and aims to provide an overview of the various neural mechanisms that contribute to learning new motor and sensory skills, and to adapting to changed circumstances, including the use of devices and implants to substitute for lost sensory or motor abilities (brain machine interfaces). The focus is on recent developments covering five major themes: - Mechanisms to improve motor performance - Neuro-rehabilitation of motor function - Mechanisms to enhance sensory perception - Cross modal interationc for enhancing sensorimotor performance - Assistive technologies to enhance sensorimotor performance This volume focuses on the translation of scientific knowledge into applications and strategies that can help restore lost function following injury or disease including assistive neuroprosthetic technologies to enhance sensorimotor performance and neurorehabilitation. - Leading authors review the state-of-the-art in their field of investigation and provide their views and perspectives for future research - Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered - All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist |
| prof dick swaab: Neurotherapy Joost Verhaagen, Elly M. Hol, Inge Huitinga, Jan Wijnholds, Arthur B. Bergen, Gerard J. Boer, Dick F. Swaab, 2009-09-14 This book focuses on the exciting recent progress in restorative neurology and neuroscience. The book includes chapters on major neurodegenerative disorders of the brain and the visual system, including Parkinson's disease, Alzheimer's disease, amyotrophic lateral sclerosis, Huntington's disease, macular degeneration, retinitis pigmentosa, glaucoma, spinal cord trauma, and multiple sclerosis. The primary goal of the book is to give an overview of new developments in translational research and in potential therapeutic strategies, including stem cell therapy, immunotherapy, gene therapy, pharmacotherapy, neuroprostheses and deep brain stimulation. - Provides the reader with a unique overview over all aspects of new advances in the therapy of neurological and psychiatric disorders - Covers all levels of biological organization including novel molecular and cellular targets, electrophysiological, anatomical and behavioural substrates of neurodegeneration and the application of whole brain in vivo imaging - Broad focus with contributions by the top scientists worldwide in the respective disciplines |
| prof dick swaab: Experimental Methods in Neuropsychology Kenneth Hugdahl, 2012-12-06 Clinical neuropsychology typically employs large standardized test-batteries to cover the cognitive deficits caused by brain lesions and neurodegenerative diseases. The neuropsychologist moves between three levels of explanation; the behavioral level, the cognitive level and the brain level. The behavioral level is measured as actual performance on a test, i. e. the obtained test score. The cognitive level refers to the underlying cognitive processes that are reflected in the test scores. The brain level, finally, refers to the neural underpinnings and substrates to the cognitive processes. The recent decades have witnessed a dramatic increase in our knowledge about cognitive processes and the underlying neural substrates. Experimental techniques and paradigms have played an important role in the accumulation of new knowledge in this field. Thus, there is a need to present a collection of experimental paradigms and techniques to neuropsychology. Some of these paradigms and techniques have however a long history in neuropsychology, like dichotic listening and EEG measures, while others are new and novel to most neuropsychologists like animal model paradigms and brain imaging and brain stimulation. Experimental techniques typically aim at discovery of causal relationships and with a focus on search for mechanisms. In the first chapter, Merill Hiscock presents an overview of experimental techniques and its adaptation in clinical neuropsychology, with a focus on behavioral techniques and methods. |
| prof dick swaab: Generations Z in Europe Christian Scholz, Anne Rennig, 2019-09-30 Generations Z in Europe brings together differing geographic perspectives from a range of researchers to present a fascinating picture of the contemporary reality for 'Gen-Z' workers from nine European countries. The findings will help readers understand the diversity of issues and commonalities for this new part of the global workforce. |
| prof dick swaab: Ethnolinguistic Prehistory George L. van Driem, 2021-05-25 This volume provides the most up-to-date and holistic but compact account of the peopling of the world from the perspective of language, genes and material culture, presenting a view from the Himalayas. The phylogeny of language families, the chronology of branching of linguistic family trees and the historical and modern geographical distribution of language communities inform us about the spread of languages and linguistic phyla. The global distribution and the chronology of spread of Y chromosomal haplogroups appears closely correlated with the spread of language families. New findings on ancient DNA have greatly enhanced our understanding of the prehistory and provenance of our biological ancestors. The archaeological study of past material cultures provides yet a third independent window onto the complex prehistory of our species. |
| prof dick swaab: Defenses in Contemporary International Criminal Law Geert-Jan G. J. Knoops, 2008 The Second Edition of Defenses in Contemporary International Criminal Law ventures farther into this uneasy territory than any previous work, offering a meticulous analysis of the case law in the post World War II Military Tribunals and the ad hoc tribunals for Rwanda and the Former Yugoslavia, with particular attention to the defenses developed, their rationales, and their origins in various municipal systems. It analyzes the defense provisions in the charters and statutes underlying these tribunals and the new International Criminal Court, while examining the first judgment in this field rendered by the Special Court for Sierra Leone, on June 20, 2007. The conceptual reach of this work includes not only the defenses recognized in the field's jurisprudence and scholarship (superior orders, duress, self-defense, insanity, necessity, mistake of law and fact, immunity of States), but also presents a strong case for the incorporation of genetic and neurobiological data into the functioning of certain defenses. Procedural mechanisms to invoke these defenses are also addressed. |
| prof dick swaab: Shapeshifters Gavin Francis, 2018-06-05 From birth to death, a lyrical exploration of the role of transformation in human life To be alive is to be in perpetual metamorphosis: growing, healing, learning, aging. In Shapeshifters, physician and writer Gavin Francis considers the inevitable changes all of our bodies undergo -- such as birth, puberty, and death, but also laughter, sleeping, and healing-and those that only some of our bodies will: like getting a tattoo, experiencing psychosis, suffering anorexia, being pregnant, or undergoing a gender transition. In Francis's hands, each event becomes an opportunity to explore the meaning of identity and the natures-biological, psychological, and philosophical-of our selves. True to its own subject, Shapeshifters combines Francis's lyrical imagination and deep knowledge of medicine and the humanities for a life-altering read. |
| prof dick swaab: Brain & Behavior Bob Garrett, Gerald Hough, 2017-10-04 Ignite your excitement about behavioral neuroscience with Brain & Behavior: An Introduction to Behavioral Neuroscience, Fifth Edition by best-selling author Bob Garrett and new co-author Gerald Hough. Garrett and Hough make the field accessible by inviting readers to explore key theories and scientific discoveries using detailed illustrations and immersive examples as their guide. Spotlights on case studies, current events, and research findings help readers make connections between the material and their own lives. A study guide, revised artwork, new animations, and an accompanying interactive eBook stimulate deep learning and critical thinking. |
| prof dick swaab: Down Syndrome: From Understanding the Neurobiology to Therapy , 2012-10-16 Down syndrome (DS) is the most common example of neurogenetic aneuploid disorder leading to mental retardation. In most cases, DS results from an extra copy of chromosome 21 (HSA21) producing deregulated gene expression in brain that gives raise to subnormal intellectual functioning. The topic of this volume is of broad interest for the neuroscience community, because it tackles the concept of neurogenomics, that is, how the genome as a whole contributes to a neurodevelopmental cognitive disorders, such as DS, and thus to the development, structure and function of the nervous system. This volume of Progress in Brain Research discusses comparative genomics, gene expression atlases of the brain, network genetics, engineered mouse models and applications to human and mouse behavioral and cognitive phenotypes. It brings together scientists of diverse backgrounds, by facilitating the integration of research directed at different levels of biological organization, and by highlighting translational research and the application of the existing scientific knowledge to develop improved DS treatments and cures. - Leading authors review the state-of-the-art in their field of investigation and provide their views and perspectives for future research - Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered - All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist |
| prof dick swaab: Enhancing Performance for Action and Perception Andrea Michelle Green, 2011 This volume of Progess in Brain Research follows on from the 32nd International Symposium of the Groupe de recherche sur le système nerveux central (GRSNC), May 2010, and aims to provide an overview of the various neural mechanisms that contribute to learning new motor and sensory skills, and to adapting to changed circumstances including the use of devices and implants to substitute for lost sensory or motor abilities (brain machine interfaces). The focus is on recent developments covering five major themes: Mechanisms to improve motor performance Neuro-rehabilitation of motor function Mechanisms to enhance sensory perception Cross modal interationc for enhancing sensorimotor performance Assistive technologies to enhance sensorimotor performance Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist. |
Prof. Dr. 与 Prof.有什么区别？ - 知乎
Prof.Dr.的称呼应该只是将两个并列，类似于国内的作者简介中“教授，博士”的职称学历列出。Prof.则不一定有Dr.的学历。 有一说将Prof. Dr. 也称为“博士生导师”，同PhD …
为什么有的教授的title是Prof有的是Dr？ - 知乎
但对于对title稍微在意的教授来说，Prof.肯定是比Dr.更厉害的title。有一次导师和美国一家公司一起写proposal，对方最开始给导师用是的Dr.，但我导师毫不犹豫地把她的title改成 …
给教授写信到底怎么称呼？ - 知乎
Sep 11, 2015 · 这里特别说一下，千万不要用Dr. Firstname或Prof. First name 开头。 这是一种调侃式的说法，比如你好哥们刚拿phd你可以doctor叫他叫着玩。 要么用 prof. Last name， 要 …
德国大学教授的头衔应该怎么理解？如果已经是工学博士，为什么 …
Dec 26, 2022 · Prof. 是指正教授（终身教授），大学里的最高职位，通常是研究所（Institute）或教研室（Lehrstule）的主任。 其实两者之间是没有谁比谁更厉害的说法，因为德国的教职和 …
英国大学中老师的“Dr”和 “Prof” 有什么本质上的区别吗？ - 知乎
一般来说，老师在没有获得终身教职的时候会叫Dr. 在之后会叫prof. 还有就是有些老师博士毕业的学校比任教的学校好，也会叫Dr. 不过整体上就是一个老师自己选择的喜好问题
德国大学教授的头衔主要有哪些？Prof. Dr. Dr. h.c. mult. 分别是什 …
德国大学教授的头衔主要有哪些？Prof. Dr. Dr. h.c. mult. 分别是什么缩写 最近在翻译同济大学和慕尼黑工业大学的协议，协议中同济大学校长的署名写的是：Prof. Dr. PEI Gang，而慕尼黑工 …
你见过最长的学术头衔什么？ - 知乎
解释：Prof.=Professor (教授)，Dr.=Doktor (博士)，rer. nat.=rerum naturalium （是拉丁语，德语是Naturwissenschaft=自然科学），habil.=Habilitation（取得在大学授课资格，博士毕业生专 …
教授、博导和研究员这三种职称的区别是什么？ - 知乎
Dec 5, 2018 · 类似的还有：不同学校的同一职称有何区别？比如，清华大学的教授和国内某不知名二本院校的教授，在职称上…
发现 - 知乎
知乎，中文互联网高质量的问答社区和创作者聚集的原创内容平台，于 2011 年 1 月正式上线，以「让人们更好的分享知识、经验和见解，找到自己的解答」为品牌使命。知乎凭借认真、专业 …
留学生给教授写邮件时要注意什么？ - 知乎
第一行Title部分，如果是你的教授，不管是Professor还是Lecturer，一般统称Prof. 后面一定要加教授的Last Name或者Full Name，见过好多留学生在Prof.后面加First Name的。 正文一般先表 …
Prof. Dr. 与 Prof.有什么区别？ - 知乎
Prof.Dr.的称呼应该只是将两个并列，类似于国内的作者简介中“教授，博士”的职称学历列出。Prof.则不一定有Dr.的学历。 有一说将Prof. Dr. 也称为“博士生导师”，同PhD …
为什么有的教授的title是Prof有的是Dr？ - 知乎
但对于对title稍微在意的教授来说，Prof.肯定是比Dr.更厉害的title。有一次导师和美国一家公司一起写proposal，对方最开始给导师用是的Dr.，但我导师毫不犹豫地把她的title改成 …
给教授写信到底怎么称呼？ - 知乎
Sep 11, 2015 · 这里特别说一下，千万不要用Dr. Firstname或Prof. First name 开头。 这是一种调侃式的说法，比如你好哥们刚拿phd你可以doctor叫他叫着玩。 要么用 prof. Last name， 要 …
德国大学教授的头衔应该怎么理解？如果已经是工学博士，为什么 …
Dec 26, 2022 · Prof. 是指正教授（终身教授），大学里的最高职位，通常是研究所（Institute）或教研室（Lehrstule）的主任。 其实两者之间是没有谁比谁更厉害的说法，因为德国的教职和 …
英国大学中老师的“Dr”和 “Prof” 有什么本质上的区别吗？ - 知乎
一般来说，老师在没有获得终身教职的时候会叫Dr. 在之后会叫prof. 还有就是有些老师博士毕业的学校比任教的学校好，也会叫Dr. 不过整体上就是一个老师自己选择的喜好问题
德国大学教授的头衔主要有哪些？Prof. Dr. Dr. h.c. mult. 分别是什 …
德国大学教授的头衔主要有哪些？Prof. Dr. Dr. h.c. mult. 分别是什么缩写 最近在翻译同济大学和慕尼黑工业大学的协议，协议中同济大学校长的署名写的是：Prof. Dr. PEI Gang，而慕尼黑工 …
你见过最长的学术头衔什么？ - 知乎
解释：Prof.=Professor (教授)，Dr.=Doktor (博士)，rer. nat.=rerum naturalium （是拉丁语，德语是Naturwissenschaft=自然科学），habil.=Habilitation（取得在大学授课资格，博士毕业生专 …
教授、博导和研究员这三种职称的区别是什么？ - 知乎
Dec 5, 2018 · 类似的还有：不同学校的同一职称有何区别？比如，清华大学的教授和国内某不知名二本院校的教授，在职称上…
发现 - 知乎
知乎，中文互联网高质量的问答社区和创作者聚集的原创内容平台，于 2011 年 1 月正式上线，以「让人们更好的分享知识、经验和见解，找到自己的解答」为品牌使命。知乎凭借认真、专业 …
留学生给教授写邮件时要注意什么？ - 知乎
第一行Title部分，如果是你的教授，不管是Professor还是Lecturer，一般统称Prof. 后面一定要加教授的Last Name或者Full Name，见过好多留学生在Prof.后面加First Name的。 正文一般先表 …
