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| pharmaceutical analytical chemistry books: Introduction to Pharmaceutical Analytical Chemistry Stig Pedersen-Bjergaard, Bente Gammelgaard, Trine G. Halvorsen, 2019-04-29 The definitive textbook on the chemical analysis of pharmaceutical drugs – fully revised and updated Introduction to Pharmaceutical Analytical Chemistry enables students to gain fundamental knowledge of the vital concepts, techniques and applications of the chemical analysis of pharmaceutical ingredients, final pharmaceutical products and drug substances in biological fluids. A unique emphasis on pharmaceutical laboratory practices, such as sample preparation and separation techniques, provides an efficient and practical educational framework for undergraduate studies in areas such as pharmaceutical sciences, analytical chemistry and forensic analysis. Suitable for foundational courses, this essential undergraduate text introduces the common analytical methods used in quantitative and qualitative chemical analysis of pharmaceuticals. This extensively revised second edition includes a new chapter on chemical analysis of biopharmaceuticals, which includes discussions on identification, purity testing and assay of peptide and protein-based formulations. Also new to this edition are improved colour illustrations and tables, a streamlined chapter structure and text revised for increased clarity and comprehension. Introduces the fundamental concepts of pharmaceutical analytical chemistry and statistics Presents a systematic investigation of pharmaceutical applications absent from other textbooks on the subject Examines various analytical techniques commonly used in pharmaceutical laboratories Provides practice problems, up-to-date practical examples and detailed illustrations Includes updated content aligned with the current European and United States Pharmacopeia regulations and guidelines Covering the analytical techniques and concepts necessary for pharmaceutical analytical chemistry, Introduction to Pharmaceutical Analytical Chemistry is ideally suited for students of chemical and pharmaceutical sciences as well as analytical chemists transitioning into the field of pharmaceutical analytical chemistry. |
| pharmaceutical analytical chemistry books: Recent Trends in Pharmaceutical Analytical Chemistry Constantinos K. Zacharis, 2021-09-01 This book covers the most recent research trends and applications of Pharmaceutical Analytical Chemistry. The included topics range from the adulteration of dietary supplements, to the determination of drugs in biological samples with the aim to investigate their pharmacokinetic properties. |
| pharmaceutical analytical chemistry books: Pharmaceutical Analysis E-Book David G. Watson, 2015-12-24 Pharmaceutical analysis determines the purity, concentration, active compounds, shelf life, rate of absorption in the body, identity, stability, rate of release etc. of a drug. Testing a pharmaceutical product involves a variety of chemical, physical and microbiological analyses. It is reckoned that over £10 billion is spent annually in the UK alone on pharmaceutical analysis, and the analytical processes described in this book are used in industries as diverse as food, beverages, cosmetics, detergents, metals, paints, water, agrochemicals, biotechnological products and pharmaceuticals. This is the key textbook in pharmaceutical analysis, now revised and updated for its fourth edition. - Worked calculation examples - Self-assessment - Additional problems (self tests) - Practical boxes - Key points boxes - New chapter on electrochemical biosensors. - New chapter on the quality control of biotechnologically produced drugs. - Extended chapter on molecular emission spectroscopy. - Now comes with an e-book on StudentConsult. - Self-assessment is interactive in the accompanying online e-book. - 65 online animations show concepts such as ionization partitioning of drug molecules etc. - ~ |
| pharmaceutical analytical chemistry books: Textbook of Practical Analytical Chemistry - E-Book Mumtaz Alam, Mymoona Akhtar, Hasan Asif, 2012-05-14 Textbook of Practical Pharmaceutical Analytical Chemistry A pharmaceutical analyst needs to have a clear understanding of the methods used to test a particular sample. This book is a sincere attempt in educating students about the concepts of the various analytical testing methods. The book has been written to cater to the needs of the B. Pharm. students in accordance with the AICTE syllabus. It can also serve as a supplementary text for the Pharm. D., D. Pharm. and the B. Sc. (Analytical Chemistry) students. Salient Features Easy narrative language encasing a student-friendly approach Basic theoretical concepts of analytical chemistry for essential understanding of the subject Experimental methods and design presented in detailed easy-to-follow formats Derivation of equivalent factor of all the drug assays mentioned in the book Coverage of all the parameters like IP limit, theory related to practical, procedure, preparation and standardization of solutions, assay procedure, complete calculations, pharmaceutical use, etc. Comprehensive presentation of testing methods and observations in a tabular form for enhanced visualization and learning Observation tables, calculations and precautions included for quick reference A must buy for all pharma students! |
| pharmaceutical analytical chemistry books: Introduction to Pharmaceutical Chemical Analysis Steen Honoré Hansen, Stig Pedersen-Bjergaard, Knut Rasmussen, 2011-10-18 This textbook is the first to present a systematic introduction to chemical analysis of pharmaceutical raw materials, finished pharmaceutical products, and of drugs in biological fluids, which are carried out in pharmaceutical laboratories worldwide. In addition, this textbook teaches the fundamentals of all the major analytical techniques used in the pharmaceutical laboratory, and teaches the international pharmacopoeias and guidelines of importance for the field. It is primarily intended for the pharmacy student, to teach the requirements in “analytical chemistry” for the 5 years pharmacy curriculum, but the textbook is also intended for analytical chemists moving into the field of pharmaceutical analysis. Addresses the basic concepts, then establishes the foundations for the common analytical methods that are currently used in the quantitative and qualitative chemical analysis of pharmaceutical drugs Provides an understanding of common analytical techniques used in all areas of pharmaceutical development Suitable for a foundation course in chemical and pharmaceutical sciences Aimed at undergraduate students of degrees in Pharmaceutical Science/Chemistry Analytical Science/Chemistry, Forensic analysis Includes many illustrative examples |
| pharmaceutical analytical chemistry books: Organic Analytical Chemistry Jag Mohan, 2003 Rapid developments in analytical techniques and the use of modern reagents in organic synthesis during the last two decades have revolutionized the approach to organic structure determination. As advanced topics in organic analysis such as spectroscopic methods are being introduced, postgraduate students (majoring in organic chemistry) have been feeling handicapped by the non-availability of a book that could uncover various aspects of qualitative and quantitative organic analysis. This book is written primarily to stimulate the interest of students of organic chemistry and pharmaceutical sciences in organic analytical chemistry. Key features: Identification and characterization of organic compounds by classical methods Mechanism of various reactions involved in the detection of functional groups and their derivatization Functional groups interfering with a given test procedure Identification of organic compounds by spectral methods (IR, UV, NMR and Mass Spectrometry) Chemical analysis by other instrumental techniques-Atomic emission spectroscopy, Electron spin resonance spectroscopy, Atomic absorption spectroscopy, flnorimetry & Phosphorimetry, Flame photometry and X-ray methods General techniques for separation and purification including Gas Chromatography and HPLC Preparation of organic compounds based on important name reactions and pharmaceutical properties Mechanism of the reactions involved in the synthesis Simple analytical techniques and specific methods of quantitative elemental, functional groups and biochemical estimations Composite spectral problems Incorporating ample modern techniques of organic analysis, this book will be of great value to graduate & postgraduate students, teachers and researchers in the field of organic chemistry and pharmaceutical sciences. |
| pharmaceutical analytical chemistry books: Pharmaceutical Chemical Analysis Ole Pedersen, 2006-01-13 Complete, referenced information in an easy-to-use formatMany of the monographs in the European Pharmacopiea, the industry standard test for certain groups of ingredients and excipients, do not describe the tests in full, but reference general methods based on test-tube chemistry. When a test fails, you need to know what went wrong, how it can be f |
| pharmaceutical analytical chemistry books: Analytical Chemistry in a GMP Environment James M. Miller, Jonathan B. Crowther, 2000-05 Based on the Laboratory Analyst Training and Certification Program ... chemists from a range of pharmaceutical companies and a few academic laboratories explain how to comply with the US Food and Drug Administration's Good Manufacturing Practice rules as analytical technologies are changing rapidly .... Among the topics are the drug development process, uniform and consistent interpretation of compliance issues, the role of statistics and basic topics in analytical chemistry, and detectors and quantitative analysis. The emphasis is on high-performance liquid chromatographic methods. |
| pharmaceutical analytical chemistry books: Statistical Methods in Analytical Chemistry Peter C. Meier, Richard E. Zünd, 2005-03-04 This new edition of a successful, bestselling book continues to provide you with practical information on the use of statistical methods for solving real-world problems in complex industrial environments. Complete with examples from the chemical and pharmaceutical laboratory and manufacturing areas, this thoroughly updated book clearly demonstrates how to obtain reliable results by choosing the most appropriate experimental design and data evaluation methods. Unlike other books on the subject, Statistical Methods in Analytical Chemistry, Second Edition presents and solves problems in the context of a comprehensive decision-making process under GMP rules: Would you recommend the destruction of a $100,000 batch of product if one of four repeat determinations barely fails the specification limit? How would you prevent this from happening in the first place? Are you sure the calculator you are using is telling the truth? To help you control these situations, the new edition: * Covers univariate, bivariate, and multivariate data * Features case studies from the pharmaceutical and chemical industries demonstrating typical problems analysts encounter and the techniques used to solve them * Offers information on ancillary techniques, including a short introduction to optimization, exploratory data analysis, smoothing and computer simulation, and recapitulation of error propagation * Boasts numerous Excel files and compiled Visual Basic programs-no statistical table lookups required! * Uses Monte Carlo simulation to illustrate the variability inherent in statistically indistinguishable data sets Statistical Methods in Analytical Chemistry, Second Edition is an excellent, one-of-a-kind resource for laboratory scientists and engineers and project managers who need to assess data reliability; QC staff, regulators, and customers who want to frame realistic requirements and specifications; as well as educators looking for real-life experiments and advanced students in chemistry and pharmaceutical science. From the reviews of Statistical Methods in Analytical Chemistry, First Edition: This book is extremely valuable. The authors supply many very useful programs along with their source code. Thus, the user can check the authenticity of the result and gain a greater understanding of the algorithm from the code. It should be on the bookshelf of every analytical chemist.-Applied Spectroscopy The authors have compiled an interesting collection of data to illustrate the application of statistical methods . . . including calibrating, setting detection limits, analyzing ANOVA data, analyzing stability data, and determining the influence of error propagation.-Clinical Chemistry The examples are taken from a chemical/pharmaceutical environment, but serve as convenient vehicles for the discussion of when to use which test, and how to make sense out of the results. While practical use of statistics is the major concern, it is put into perspective, and the reader is urged to use plausibility checks.-Journal of Chemical Education The discussion of univariate statistical tests is one of the more thorough I have seen in this type of book . . . The treatment of linear regression is also thorough, and a complete set of equations for uncertainty in the results is presented . . . The bibliography is extensive and will serve as a valuable resource for those seeking more information on virtually any topic covered in the book.-Journal of American Chemical Society This book treats the application of statistics to analytical chemistry in a very practical manner. [It] integrates PC computing power, testing programs, and analytical know-how in the context of good manufacturing practice/good laboratory practice (GMP/GLP) . . .The book is of value in many fields of analytical chemistry and should be available in all relevant libraries.-Chemometrics and Intelligent Laboratory Systems |
| pharmaceutical analytical chemistry books: Robustness of Analytical Chemical Methods and Pharmaceutical Technological Products M.M.W.B. Hendriks, J.H. de Boer, A.K. Smilde, 1996-12-11 In analytical chemistry and pharmaceutical technology attention is increasingly focussed on improving the quality of methods and products. This book aims at fostering the awareness of the potential of existing mathematical and statistical methods to improve this quality. It provides procedures and ideas on how to make a product or a method less sensitive to small variations in influencing factors. Major issues covered are robustness and stability improvement and ruggedness testing. General strategies and a theoretical introduction to these methods are described, and thorough overviews of methods used in both application areas and descriptions of practical applications are given.Features of this book:• Gives a good overview of mathematical and statistical methods used in two application areas, i.e. pharmaceutical technology and analytical chemistry• Illustrates the different approaches available to attain robustness• Gives ideas on how to use methods in practical situations.The book is intended for those who develop and optimize, and are responsible for the overall quality of, analytical methods and pharmaceutical technological products and procedures. |
| pharmaceutical analytical chemistry books: Pharmaceutical Analysis for Small Molecules Behnam Davani, 2017-08-01 A comprehensive introduction for scientists engaged in new drug development, analysis, and approvals Each year the pharmaceutical industry worldwide recruits thousands of recent science graduates—especially chemistry, analytical chemistry, pharmacy, and pharmaceutical majors—into its ranks. However, because of their limited background in pharmaceutical analysis most of those new recruits find making the transition from academia to industry very difficult. Designed to assist both recent graduates, as well as experienced chemists or scientists with limited regulatory, compendial or pharmaceutical analysis background, make that transition, Pharmaceutical Analysis for Small Molecules is a concise, yet comprehensive introduction to the drug development process and analysis of chemically synthesized, small molecule drugs. It features contributions by distinguished experts in the field, including editor and author, Dr. Behnam Davani, an analytical chemist with decades of technical management and teaching experience in compendial, regulatory, and industry. This book provides an introduction to pharmaceutical analysis for small molecules (non-biologics) using commonly used techniques for drug characterization and performance tests. The driving force for industry to perform pharmaceutical analyses is submission of such data and supporting documents to regulatory bodies for drug approval in order to market their products. In addition, related required supporting studies including good laboratory/documentation practices including analytical instrument qualification are highlighted in this book. Topics covered include: Drug Approval Process and Regulatory Requirements (private standards) Pharmacopeias and Compendial Approval Process (public standards) Common methods in pharmaceutical analysis (typically compendial) Common Calculations for assays and impurities and other specific tests Analytical Method Validation, Verification, Transfer Specifications including how to handle out of specification (OOS) and out of trend (OOT) Impurities including organic, inorganic, residual solvents and elemental impurities Good Documentation Practices for regulatory environment Management of Analytical Laboratories Analytical Instrument Qualifications including IQ, OQ, PQ and VQ Due to global nature of pharmaceutical industry, other topics on both regulatory (ICH) and Compendial harmonization are also highlighted. Pharmaceutical Analysis for Small Molecules is a valuable working resource for scientists directly or indirectly involved with the drug development process, including analytical chemists, pharmaceutical scientists, pharmacists, and quality control/quality assurance professionals. It also is an excellent text/reference for graduate students in analytical chemistry, pharmacy, pharmaceutical and regulatory sciences. |
| pharmaceutical analytical chemistry books: Analytical Chemistry Bryan M. Ham, Aihui MaHam, 2015-10-01 A comprehensive study of analytical chemistry providing the basics of analytical chemistry and introductions to the laboratory Covers the basics of a chemistry lab including lab safety, glassware, and common instrumentation Covers fundamentals of analytical techniques such as wet chemistry, instrumental analyses, spectroscopy, chromatography, FTIR, NMR, XRF, XRD, HPLC, GC-MS, Capillary Electrophoresis, and proteomics Includes ChemTech an interactive program that contains lesson exercises, useful calculators and an interactive periodic table Details Laboratory Information Management System a program used to log in samples, input data, search samples, approve samples, and print reports and certificates of analysis |
| pharmaceutical analytical chemistry books: Essentials of Pharmaceutical Chemistry Donald Cairns, 2012 An introduction to pharmaceutical chemistry for undergraduate pharmacy, chemistry and medicinal chemistry students. Essentials of Pharmaceutical Chemistry is a chemistry introduction that covers all of the core material necessary to provide an understanding of the basic chemistry of drug molecules. Now a core text on many university courses, it contains numerous worked examples and problems |
| pharmaceutical analytical chemistry books: Pharmaceutical Chemistry Christine Bladon, 2002-04-03 Providing a broad introduction to the growing field, this book explores the way in which peptides, proteins, nucleic acids and carbohydrates used therapeutically. With help of numerous illustrations, it covers both the compounds and how therapeutics exert their influence throuhg an understanding of biological processes. * Includes the latest developments in the field * Covers the various strategies behind the development and production of a range of key clinically useful compounds * Focuses on the concepts and ideas of why compounds are developed as pharmaceuticals * Provides many examples and problems Invaluable to all students of chemistry, medicinal and pharmaceutical chemistry, pharmacy and pharmacology. Will also be of interest to researchers and professionals needing a concise, up-to-date account of this subject. |
| pharmaceutical analytical chemistry books: Introduction to Pharmaceutical Analytical Chemistry Stig Pedersen-Bjergaard, Bente Gammelgaard, Trine G. Halvorsen, 2026-04-13 |
| pharmaceutical analytical chemistry books: Pharmaceutical Analysis,A Textbook for Pharmacy Students and Pharmaceutical Chemists,3 David G. Watson, 2012 This introductory text highlights the most important aspects of a wide range of techniques used in the control of the quality of pharmaceuticals. Written with the needs of the student in mind, this clear, practical guide includes self-testing sections with arithmetical examples and tests to help students brush up on their arithmetical skills in an applied context. |
| pharmaceutical analytical chemistry books: HPLC for Pharmaceutical Scientists Yuri V. Kazakevich, Rosario LoBrutto, 2007-02-16 HPLC for Pharmaceutical Scientists is an excellent book for both novice and experienced pharmaceutical chemists who regularly use HPLC as an analytical tool to solve challenging problems in the pharmaceutical industry. It provides a unified approach to HPLC with an equal and balanced treatment of the theory and practice of HPLC in the pharmaceutical industry. In-depth discussion of retention processes, modern HPLC separation theory, properties of stationary phases and columns are well blended with the practical aspects of fast and effective method development and method validation. Practical and pragmatic approaches and actual examples of effective development of selective and rugged HPLC methods from a physico-chemical point of view are provided. This book elucidates the role of HPLC throughout the entire drug development process from drug candidate inception to marketed drug product and gives detailed specifics of HPLC application in each stage of drug development. The latest advancements and trends in hyphenated and specialized HPLC techniques (LC-MS, LC-NMR, Preparative HPLC, High temperature HPLC, high pressure liquid chromatography) are also discussed. |
| pharmaceutical analytical chemistry books: Pharmaceutical Process Chemistry Takayuki Shioiri, Kunisuke Izawa, Toshiro Konoike, 2010-12-09 Covering the whole area of process chemistry in the pharmaceutical industry, this monograph provides the essential knowledge on the basic chemistry needed for future development and key industrial techniques, as well as morphology, engineering and regulatory compliances. Application-oriented and well structured, the authors include recent examples of excellent industrial production of active pharmaceutical ingredients. |
| pharmaceutical analytical chemistry books: Chromatographic Analysis of Pharmaceuticals John A. Adamovics, 2017-09-29 Updated and revised throughout. Second Edition explores the chromatographic methods used for the measurement of drugs, impurities, and excipients in pharmaceutical preparations--such as tablets, ointments, and injectables. Contains a 148-page table listing the chromatographic data of over 1300 drugs and related substances--including sample matrix analyzed, sample handling procedures, column packings, mobile phase, mode of detection, and more. |
| pharmaceutical analytical chemistry books: NMR Spectroscopy in Pharmaceutical Analysis Iwona Wawer, Bernd Diehl, 2017-07-07 For almost a decade, quantitative NMR spectroscopy (qNMR) has been established as valuable tool in drug analysis. In all disciplines, i. e. drug identification, impurity profiling and assay, qNMR can be utilized. Separation techniques such as high performance liquid chromatography, gas chromatography, super fluid chromatography and capillary electrophoresis techniques, govern the purity evaluation of drugs. However, these techniques are not always able to solve the analytical problems often resulting in insufficient methods. Nevertheless such methods find their way into international pharmacopoeias. Thus, the aim of the book is to describe the possibilities of qNMR in pharmaceutical analysis. Beside the introduction to the physical fundamentals and techniques the principles of the application in drug analysis are described: quality evaluation of drugs, polymer characterization, natural products and corresponding reference compounds, metabolism, and solid phase NMR spectroscopy for the characterization drug substances, e.g. the water content, polymorphism, and drug formulations, e.g. tablets, powders. This part is accompanied by more special chapters dealing with representative examples. They give more detailed information by means of concrete examples. - Combines theory, techniques, and concrete applications—all of which closely resemble the laboratory experience - Considers international pharmacopoeias, addressing the concern for licensing - Features the work of academics and researchers, appealing to a broad readership |
| pharmaceutical analytical chemistry books: History of Analytical Chemistry Ferenc Szabadváry, 2016-01-22 History of Analytical Chemistry is a systematic account of the historical development of analytical chemistry spanning about 4,000 years. Many scientists who have helped to develop the methods of analytical chemistry are mentioned. Various methods of analysis are discussed, including electrogravimetry, optical methods, electrometric analysis, radiochemical analysis, and chromatography. This volume is comprised of 14 chapters and begins with an overview of analytical chemistry in ancient Greece, the origin of chemistry, and the earliest knowledge of analysis. The next chapter focuses on analytical chemistry during the Middle Ages, with emphasis on alchemy. Analytical knowledge during the period of iatrochemistry and the development of analytical chemistry during the phlogiston period are then examined. Subsequent chapters deal with the development of the fundamental laws of chemistry, including the principle of the indestructibility of matter; analytical chemistry during the period of Berzelius; and developments in qualitative and gravimetric analysis. Elementary organic analysis is also considered, along with the development of the theory of analytical chemistry. This book will be helpful to chemists as well as students and researchers in the field of analytical chemistry. |
| pharmaceutical analytical chemistry books: Analytical Techniques in the Pharmaceutical Sciences Anette Müllertz, Yvonne Perrie, Thomas Rades, 2016-08-30 The aim of this book is to present a range of analytical methods that can be used in formulation design and development and focus on how these systems can be applied to understand formulation components and the dosage form these build. To effectively design and exploit drug delivery systems, the underlying characteristic of a dosage form must be understood--from the characteristics of the individual formulation components, to how they act and interact within the formulation, and finally, to how this formulation responds in different biological environments. To achieve this, there is a wide range of analytical techniques that can be adopted to understand and elucidate the mechanics of drug delivery and drug formulation. Such methods include e.g. spectroscopic analysis, diffractometric analysis, thermal investigations, surface analytical techniques, particle size analysis, rheological techniques, methods to characterize drug stability and release, and biological analysis in appropriate cell and animal models. Whilst each of these methods can encompass a full research area in their own right, formulation scientists must be able to effectively apply these methods to the delivery system they are considering. The information in this book is designed to support researchers in their ability to fully characterize and analyze a range of delivery systems, using an appropriate selection of analytical techniques. Due to its consideration of regulatory approval, this book will also be suitable for industrial researchers both at early stage up to pre-clinical research. |
| pharmaceutical analytical chemistry books: Pharmaceutical Chemistry Chris Rostron, Jill Barber, 2021 Taking medication is a common occurrence for many people, whether it is to soothe an aching head, regulate blood sugars, or to treat life threatening conditions. In the UK alone, over 900 million prescriptions are dispensed every year. Overseeing all of this are pharmacists: experts in medicines and their use.Pharmaceutical Chemistry provides a wide-ranging overview of organic chemistry as applied to the study and practice of pharmacy. Drugs are simply chemicals, so to fully understand their manufacture, formulation, and the way they work in our bodies, a knowledge of organic compounds and their reactions is essential.By reading this book, students will begin to understand how a drug molecule is made; the process that turns it into a medicine; the role the pharmacist has when dispensing that medicine; and what happens in the body when it is taken. Most importantly, the text shows how each of these aspects are integrated, helping you to see the bigger picture. Pharmaceutical Chemistry is available for students and institutions to purchase in a variety of formats, and is supported by online resources.The ebook offers a mobile experience and convenient access: www.oxfordtextbooks.co.uk/ebooks.The online resources include:For students:- Self-assessment questions to help the reader to check and reinforce understanding of the material introduced in each chapter- Bonus material to accompany chapters 3, 7 and 11- Answers to self-check questions from the bookFor registered adopters of the book:- Figures from the book, available to download. |
| pharmaceutical analytical chemistry books: HPLC Methods for Clinical Pharmaceutical Analysis Hermann Mascher, 2012-02-13 Filling a gap in the literature for a hands-on guide focusing on everyday laboratory challenges, this English edition has been expanded and revised using the feedback received on the successful German precursor. Throughout the book, Professor Mascher draws on his 30 years of experience and provides abundant practical advice, troubleshooting and other hints highlighted in boxes, as well as a broad selection of walkthrough case studies. Based on a course taught by the author, the first part of the book intuitively explains all steps of routine bioanalysis and explains how to set up a robust, inexpensive and effi cient method for a given substance. In the second part he includes 20 worked example cases that highlight common challenges and how to overcome them. With its appendix containing tried-and-tested analytical methods for 100 clinically relevant substances from the author`s own laboratory, complete with spectral and MS data as well as literature references and basic pharmacokinetic information, this is a life-long companion for everyone working in clinical, pharmaceutical and biochemical analysis. Comments to the German book: The book comes to life through its examples, showing not only what did work in the author's laboratory, but also what didn't. ChemieReport Indispensable for novices, while even old hands will be able to expand their knowledge. A collection of analytical data for ca. 100 substances completes the book's offering, leaving almost nothing to be desired. pharmind |
| pharmaceutical analytical chemistry books: Handbook of Analytical Quality by Design Sarwar Beg, Md Saquib Hasnain, Mahfoozur Rahman, Waleed H Almalki, 2021-01-09 Handbook of Analytical Quality by Design addresses the steps involved in analytical method development and validation in an effort to avoid quality crises in later stages. The AQbD approach significantly enhances method performance and robustness which are crucial during inter-laboratory studies and also affect the analytical lifecycle of the developed method. Sections cover sample preparation problems and the usefulness of the QbD concept involving Quality Risk Management (QRM), Design of Experiments (DoE) and Multivariate (MVT) Statistical Approaches to solve by optimizing the developed method, along with validation for different techniques like HPLC, UPLC, UFLC, LC-MS and electrophoresis. This will be an ideal resource for graduate students and professionals working in the pharmaceutical industry, analytical chemistry, regulatory agencies, and those in related academic fields. - Concise language for easy understanding of the novel and holistic concept - Covers key aspects of analytical development and validation - Provides a robust, flexible, operable range for an analytical method with greater excellence and regulatory compliance |
| pharmaceutical analytical chemistry books: Quantitative Calculations in Pharmaceutical Practice and Research Themistolēs P. Chatzēiōannou, 1993 This practical handbook aims at familiarizing students and scientists with the most common calculations encountered in the pharmaceutical sciences. It consolidates theoretical knowledge by applying it to the solution of real problems. Each chapter provides a short introduction of the relevant theory and includes equations to aid the comprehension of the theoretical principle. The text includes 220 solved examples and 250 problems and answers. Annotation copyright by Book News, Inc., Portland, OR |
| pharmaceutical analytical chemistry books: Solubility in Pharmaceutical Chemistry Christoph Saal, Anita Nair, 2020-01-20 This book describes the physicochemical fundamentals and biomedical principles of drug solubility. Methods to study and predict solubility in silico and in vitro are described and the role of solubility in a medicinal chemistry and pharmaceutical industry context are discussed. Approaches to modify and control solubility of a drug during the manufacturing process and of the pharmaceutical product are essential practical aspects of this book. |
| pharmaceutical analytical chemistry books: Introduction to Pharmaceutical Analysis R R Badwaik, Shiv Shankar Shukla, Dulal Krishna Tripathi, 2019-12-02 The content of the book, Introduction to Pharmaceutical Analysis, has been prepared primarily in accordance to the syllabus prepared by the Pharmacy Council of India for B. Pharm 1st semester course. However, the content of the book is not limited to the syllabus only, it provides the information which are bare necessary to understand a particular concept but beyond the syllabus. Moreover, there are two Appendices, Appendix I and II at the end. These are equally important and need to be known. One is Test solutions and the other one is for Volumetric solutions. In fact, many students do not know the difference between these solutions that are essential for analysis. How to prepare all these solutions are mentioned there. Hence, the book would be a real helpful to all those who are associated to pharmaceutical analysis, may be during their post-graduation and during service pharmaceutical industry. |
| pharmaceutical analytical chemistry books: Essentials of Pharmaceutical Analysis Muhammad Sajid Hamid Akash, Kanwal Rehman, 2019-12-17 Recent advances in the pharmaceutical sciences and biotechnology have facilitated the production, design, formulation and use of various types of pharmaceuticals and biopharmaceuticals. This book provides detailed information on the background, basic principles, and components of techniques used for the analysis of pharmaceuticals and biopharmaceuticals. Focusing on those analytical techniques that are most frequently used for pharmaceuticals, it classifies them into three major sections and 19 chapters, each of which discusses a respective technique in detail. Chiefly intended for graduate students in the pharmaceutical sciences, the book will familiarize them with the components, working principles and practical applications of these indispensable analytical techniques. |
| pharmaceutical analytical chemistry books: Formulation and Analytical Development for Low-Dose Oral Drug Products Jack Zheng, 2009-02-09 There are unique challenges in the formulation, manufacture, analytical chemistry, and regulatory requirements of low-dose drugs. This book provides an overview of this specialized field and combines formulation, analytical, and regulatory aspects of low-dose development into a single reference book. It describes analytical methodologies like dissolution testing, solid state NMR, Raman microscopy, and LC-MS and presents manufacturing techniques such as granulation, compaction, and compression. Complete with case studies and a discussion of regulatory requirements, this is a core reference for pharmaceutical scientists, regulators, and graduate students. |
| pharmaceutical analytical chemistry books: Chromatographic Methods Development Gregory K. Webster, Laila Kott, 2019-10-28 This book is a comprehensive compilation of modern and cutting-edge chromatographic techniques written by pharmaceutical industry experts, academics, and vendors in the field. This book is an inclusive guide to developing all chromatographic methods (such as liquid chromatography and gas chromatography). It covers modern techniques for developing methods using chromatographic development software, requirements for validations, discussion on orthogonality, and how to transfer methods from HPLC to UHPLC. The text introduces some newer techniques that are heavily employed by chemists analyzing proteins and RNAi, as well as novel techniques such as counter current chromatography. This book is valuable for both the novice starting out in undergraduate labs and those who are new to the pharmaceutical industry and is a useful reference for seasoned analysts. |
| pharmaceutical analytical chemistry books: Pharmaceutical Chemistry David G. Watson, 2011 Intends to define the area of pharmaceutical chemistry as distinct from medicinal chemistry. This book emphasizes on the physicochemical properties of drug molecules and, in so far as they are known, the way that these properties govern the interaction of the drug with its target. |
| pharmaceutical analytical chemistry books: Solid-State Properties of Pharmaceutical Materials Stephen R. Byrn, George Zografi, Xiaoming (Sean) Chen, 2017-08-28 Presents a detailed discussion of important solid-state properties, methods, and applications of solid-state analysis Illustrates the various phases or forms that solids can assume and discussesvarious issues related to the relative stability of solid forms and tendencies to undergo transformation Covers key methods of solid state analysis including X-ray powder diffraction, thermal analysis, microscopy, spectroscopy, and solid state NMR Reviews critical physical attributes of pharmaceutical materials, mainly related to drug substances, including particle size/surface area, hygroscopicity, mechanical properties, solubility, and physical and chemical stability Showcases the application of solid state material science in rational selection of drug solid forms, analysis of various solid forms within drug substance and the drug product, and pharmaceutical product development Introduces appropriate manufacturing and control procedures using Quality by Design, and other strategies that lead to safe and effective products with a minimum of resources and time |
| pharmaceutical analytical chemistry books: A Textbook of Pharmaceutical Analysis Kenneth Antonio Connors, 1975 |
| pharmaceutical analytical chemistry books: Computational Pharmaceutical Solid State Chemistry Yuriy A. Abramov, 2016-04-18 This book is the first to combine computational material science and modeling of molecular solid states for pharmaceutical industry applications. • Provides descriptive and applied state-of-the-art computational approaches and workflows to guide pharmaceutical solid state chemistry experiments and to support/troubleshoot API solid state selection • Includes real industrial case examples related to application of modeling methods in problem solving • Useful as a supplementary reference/text for undergraduate, graduate and postgraduate students in computational chemistry, pharmaceutical and biotech sciences, and materials science |
| pharmaceutical analytical chemistry books: Remington Adeboye Adejare, 2020-11-03 The PCP's Bicentennial Edition Remington: The Science and Practice of Pharmacy, Twenty Third Edition, offers a trusted, completely updated source of information for education, training, and development of pharmacists. Published for the first time with Elsevier, this edition includes coverage of biologics and biosimilars as uses of those therapeutics have increased substantially since the previous edition. Also discussed are formulations, drug delivery (including prodrugs, salts, polymorphism. With clear, detailed color illustrations, fundamental information on a range of pharmaceutical science areas, and information on new developments in industry, pharmaceutical industry scientists, especially those involved in drug discovery and development will find this edition of Remington an essential reference. Intellectual property professionals will also find this reference helpful to cite in patents and resulting litigations. Additional graduate and postgraduate students in Pharmacy and Pharmaceutical Sciences will refer to this book in courses dealing with medicinal chemistry and pharmaceutics. - Contains a comprehensive source of principles of drug discovery and development topics, especially for scientists that are new in the pharmaceutical industry such as those with trainings/degrees in chemistry and engineering - Provides a detailed source for formulation scientists and compounding pharmacists, from produg to excipient issues - Updates this excellent source with the latest information to verify facts and refresh on basics for professionals in the broadly defined pharmaceutical industry |
| pharmaceutical analytical chemistry books: Method Validation in Pharmaceutical Analysis Joachim Ermer, John H. McB. Miller, 2006-03-06 Adopting a practical approach, the authors provide a detailed interpretation of the existing regulations (GMP, ICH), while also discussing the appropriate calculations, parameters and tests. The book thus allows readers to validate the analysis of pharmaceutical compounds while complying with both the regulations as well as the industry demands for robustness and cost effectiveness. Following an introduction to the basic parameters and tests in pharmaceutical validation, including specificity, linearity, range, precision, accuracy, detection and quantitation limits, the text focuses on a life-cycle approach to validation and the integration of validation into the whole analytical quality assurance system. The whole is rounded off with a look at future trends. With its first-hand knowledge of the industry as well as regulating bodies, this is an invaluable reference for analytical chemists, the pharmaceutical industry, pharmaceutists, QA officers, and public authorities. |
| pharmaceutical analytical chemistry books: Essentials of Inorganic Chemistry Katja A. Strohfeldt, 2015-02-16 A comprehensive introduction to inorganic chemistry and, specifically, the science of metal-based drugs, Essentials of Inorganic Chemistry describes the basics of inorganic chemistry, including organometallic chemistry and radiochemistry, from a pharmaceutical perspective. Written for students of pharmacy and pharmacology, pharmaceutical sciences, medicinal chemistry and other health-care related subjects, this accessible text introduces chemical principles with relevant pharmaceutical examples rather than as stand-alone concepts, allowing students to see the relevance of this subject for their future professions. It includes exercises and case studies. |
| pharmaceutical analytical chemistry books: Pharmaceutical Analysis David C. Lee, Michael Webb, 2008-06-26 This book concentrates on the analytical aspects of drug development and manufacture, focusing on the analysis of the active ingredient or drug substance. It provides those joining the industry or other areas of pharmaceutical research with a source of reference to a broad range of techniques and their applications, allowing them to choose the most appropriate analytical technique for a particular purpose.· Quality Control and Regulation· Development of Achiral Separation Methods in Pharmaceutical Analysis· Chiral Analysis of Pharmaceuticals· Nuclear Magnetic Resonance Spectroscopy in Pharmaceutical Analysis· Mass Spectrometry in Pharmaceutical Analysis· Vibrational Spectroscopy in Pharmaceutical Analysis· Solid-State Analysis and Polymorphism· Microscopy and Imaging in Pharmaceutical Analysis· Process Analysis in the Pharmaceutical Industry |
| pharmaceutical analytical chemistry books: High-Throughput Analysis in the Pharmaceutical Industry Perry G. Wang, 2008-08-20 The introduction of combinatorial chemistry technology has increased the amount of compounds generated in a year from 50 to 2000. Conventional analytical approaches simply cannot keep up. These circumstances have caused drug discovery to take on the shape of a bottleneck, like traffic through a toll booth. In order to break the bottleneck, a corres |
Global pharmaceutical industry - statistics & facts | Statista
Nov 22, 2024 · Consequently, pharmaceutical companies came into the public’s focus, with the pressure to provide results quickly growing. This was especially true for the global leaders of …
Pharmaceutical industry in Germany - statistics & facts
Jan 13, 2025 · The pharmaceutical market is lucrative as medicines are essential to daily life and something that almost everyone will need at some point. Furthermore, it is an industry heavily …
Pharmaceutical industry in Poland - statistics & facts
Apr 25, 2025 · Pharmaceutical spending in Poland has shown a significant upward trend in recent years, reflecting a growing consumer investment in health-related products. In 2023, ...
Pharmaceutical industry in Canada - Statistics & Facts
Feb 9, 2024 · The pharmaceutical industry in Canada is a significant economic segment, employing more than 33 thousand people in the manufacturing sector alone. However, …
Pharmaceutical industry in Italy - Statistics & Facts
Jul 18, 2024 · Industry overview 12 Premium Statistic Pharmaceutical market: worldwide revenue 2001-2024 Basic Statistic Revenue of leading European pharmaceutical markets 2023
Pharmaceutical industry in Argentina - Statistics & Facts
Jan 10, 2024 · The pharmaceutical landscape in Argentina is characterized by a wide variety of over-the-counter (OTC), and prescription drug categories. These include therapeutic …
U.S. pharmaceutical industry - statistics & facts | Statista
Nov 22, 2024 · Top 50 pharmaceutical companies - Rx sales and R&D spending 2023 Leading 50 global pharmaceutical companies by prescription sales and R&D spending in 2023 (in billion …
Pharmaceutical market in Italy - Statistics & Facts | Statista
Premium Statistic Pharmaceutical enterprises in Italy 2023, by capital provenience Market overview Premium Statistic Global pharmaceutical market - revenue distribution 2010-2023, by …
Pharmaceutical industry in Brazil - Statistics & Facts
Feb 12, 2025 · The pharmaceutical industry in Brazil is composed of over 200 companies, of which more than half are located in São Paulo, the most populous city in Brazil. In 2022, ...
Pharmaceutical market in the Philippines - statistics & facts
Dec 21, 2023 · Pharmaceutical products are supplied by multinational companies (MNCs) and local companies. MNCs are marketing and distributing finished medicine products and raw and …
Global pharmaceutical industry - statistics & facts | Statista
Nov 22, 2024 · Consequently, pharmaceutical companies came into the public’s focus, with the pressure to provide results quickly growing. This was especially true for the global leaders of …
Pharmaceutical industry in Germany - statistics & facts
Jan 13, 2025 · The pharmaceutical market is lucrative as medicines are essential to daily life and something that almost everyone will need at some point. Furthermore, it is an industry heavily …
Pharmaceutical industry in Poland - statistics & facts
Apr 25, 2025 · Pharmaceutical spending in Poland has shown a significant upward trend in recent years, reflecting a growing consumer investment in health-related products. In 2023, ...
Pharmaceutical industry in Canada - Statistics & Facts
Feb 9, 2024 · The pharmaceutical industry in Canada is a significant economic segment, employing more than 33 thousand people in the manufacturing sector alone. However, …
Pharmaceutical industry in Italy - Statistics & Facts
Jul 18, 2024 · Industry overview 12 Premium Statistic Pharmaceutical market: worldwide revenue 2001-2024 Basic Statistic Revenue of leading European pharmaceutical markets 2023
Pharmaceutical industry in Argentina - Statistics & Facts
Jan 10, 2024 · The pharmaceutical landscape in Argentina is characterized by a wide variety of over-the-counter (OTC), and prescription drug categories. These include therapeutic …
U.S. pharmaceutical industry - statistics & facts | Statista
Nov 22, 2024 · Top 50 pharmaceutical companies - Rx sales and R&D spending 2023 Leading 50 global pharmaceutical companies by prescription sales and R&D spending in 2023 (in billion …
Pharmaceutical market in Italy - Statistics & Facts | Statista
Premium Statistic Pharmaceutical enterprises in Italy 2023, by capital provenience Market overview Premium Statistic Global pharmaceutical market - revenue distribution 2010-2023, by …
Pharmaceutical industry in Brazil - Statistics & Facts
Feb 12, 2025 · The pharmaceutical industry in Brazil is composed of over 200 companies, of which more than half are located in São Paulo, the most populous city in Brazil. In 2022, ...
Pharmaceutical market in the Philippines - statistics & facts
Dec 21, 2023 · Pharmaceutical products are supplied by multinational companies (MNCs) and local companies. MNCs are marketing and distributing finished medicine products and raw and …
