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| npj systems biology and applications impact factor: Systems Medicine , 2020-08-24 Technological advances in generated molecular and cell biological data are transforming biomedical research. Sequencing, multi-omics and imaging technologies are likely to have deep impact on the future of medical practice. In parallel to technological developments, methodologies to gather, integrate, visualize and analyze heterogeneous and large-scale data sets are needed to develop new approaches for diagnosis, prognosis and therapy. Systems Medicine: Integrative, Qualitative and Computational Approaches is an innovative, interdisciplinary and integrative approach that extends the concept of systems biology and the unprecedented insights that computational methods and mathematical modeling offer of the interactions and network behavior of complex biological systems, to novel clinically relevant applications for the design of more successful prognostic, diagnostic and therapeutic approaches. This 3 volume work features 132 entries from renowned experts in the fields and covers the tools, methods, algorithms and data analysis workflows used for integrating and analyzing multi-dimensional data routinely generated in clinical settings with the aim of providing medical practitioners with robust clinical decision support systems. Importantly the work delves into the applications of systems medicine in areas such as tumor systems biology, metabolic and cardiovascular diseases as well as immunology and infectious diseases amongst others. This is a fundamental resource for biomedical students and researchers as well as medical practitioners who need to need to adopt advances in computational tools and methods into the clinical practice. Encyclopedic coverage: ‘one-stop’ resource for access to information written by world-leading scholars in the field of Systems Biology and Systems Medicine, with easy cross-referencing of related articles to promote understanding and further research Authoritative: the whole work is authored and edited by recognized experts in the field, with a range of different expertise, ensuring a high quality standard Digitally innovative: Hyperlinked references and further readings, cross-references and diagrams/images will allow readers to easily navigate a wealth of information |
| npj systems biology and applications impact factor: Artificial Intelligence in Science Challenges, Opportunities and the Future of Research OECD, 2023-06-26 The rapid advances of artificial intelligence (AI) in recent years have led to numerous creative applications in science. Accelerating the productivity of science could be the most economically and socially valuable of all the uses of AI. |
| npj systems biology and applications impact factor: Integrative Approaches in Environmental Health and Exposome Research Élodie Giroux, Francesca Merlin, Yohan Fayet, 2023-06-12 Research on the relationship between health and the environment in a postgenomic context is increasingly aimed at understanding the various exposures as a whole, simultaneously taking into account data pertaining to the biology of organisms and the physical and social environment. Exposome research is a paradigmatic case of this new trend in environmental health studies. This book takes a multidisciplinary approach focusing on the conceptual, epistemological, and sociological reflections in the latest research on environmental and social determinants of health and disease. It offers a combination of theoretical and practical approaches and the authors are scholars from a multidisciplinary background (epidemiology, geography, philosophy of medicine and biology, sociology). Crucially, the book balances the benefit and cost of the integration of biological and social factors when modelling aetiology of disease. |
| npj systems biology and applications impact factor: Metabolic and Bioenergetic Drivers of Neurodegenerative Disease: Neurodegenerative Disease Research and Commonalities with Metabolic Diseases , 2020-07-30 Metabolic Drivers and Bioenergetic Components of Neurodegenerative Disease summarizes recent developments in intervention trials in neurodegenerative diseases, particularly Alzheimer's and Parkinson's, as well as increasing evidence for the overlap between drivers of metabolic and neurodegenerative disease that impact mitochondrial function and bioenergetics, and subsequently cellular function and pathophysiology. Topics covered include Brain Glucose and Ketone Utilization in Brain Ageing and Neurodegenerative Diseases; the Mitochondrial Hypothesis: Dysfunction, Bioenergetic Defects, and the Metabolic Link to Alzheimer's Disease; the Metabolic Impact on Neuroinflammation and Microglial Modulation in Neurodegenerative Diseases, the Impact of Circadian and Diurnal Rhythms on Cellular Metabolic Function and Neurodegenerative Diseases, and much more. - Summarizes the current status of and future research in Alzheimer's and Parkinson's diseases - Reviews the impact of the metabolic hypothesis on underlying mechanisms of neurodegenerative diseases |
| npj systems biology and applications impact factor: Artificial intelligence in science Alistair Nolan, 2024-01-05 The rapid advances of artificial intelligence (AI) in recent years have led to numerous creative applications in science. Accelerating the productivity of science could be the most economically and socially valuable of all the uses of AI. Utilising AI to accelerate scientific productivity will support the ability of OECD countries to grow, innovate and meet global challenges, from climate change to new contagions. This publication is aimed at a broad readership, including policy makers, the public, and stakeholders in all areas of science. It is written in non-technical language and gathers the perspectives of prominent researchers and practitioners. The book examines various topics, including the current, emerging, and potential future uses of AI in science, where progress is needed to better serve scientific advancements, and changes in scientific productivity. Additionally, it explores measures to expedite the integration of AI into research in developing countries. A distinctive contribution is the book’s examination of policies for AI in science. Policy makers and actors across research systems can do much to deepen AI’s use in science, magnifying its positive effects, while adapting to the fast-changing implications of AI for research governance. ABOUT THE AUTHOR Alistair Nolan is a Senior Policy Analyst in the OECD’s Directorate for Science, Technology and Innovation. Prior to the OECD, Mr. Nolan led a range of industry-related analytic and technical assistance projects with the United Nations. Over a number of years at the OECD Alistair has been involved in work on skills and education assessment, entrepreneurship, private sector development and policy evaluation. Alistair is currently coordinating various streams of OECD work on artificial intelligence, and is overseeing the work on AI diffusion under the AI-WIPS project. Mr. Nolan oversaw preparation of the 2017 publication The Next Production Revolution: Implications for Governments and Business, which examines a variety of emerging technologies, their impacts and policy implications, and which was referenced at the start of the 2017 G7 Taormina Action Plan. Mr. Nolan led work on 2020 publication The Digitalisation of Science, Technology and Innovation : Key Developments and Policies, which among other topics addresses the role of AI in advanced production. |
| npj systems biology and applications impact factor: Signal Analysis in Pharmacovigilance Anoop Kumar, 2024-09-26 This book provides detailed concepts and information on principles and processes of signal analysis in pharmacovigilance along with case studies. It covers the fundamental concepts and principles of pharmacovigilance, emphasizing the need for robust signal detection and analysis methods. The book reviews the diverse array of databases and tools employed for signal detection, including electronic health records (EHRs), social media mining, claims data, and distributed data networks. In turn, the book discusses the application of molecular dynamics, molecular docking, and the use of the FDA Adverse Event Reporting System (FAERS) database in signal analysis. Toward the end, the book explores the identification, validation, and assessment of signals associated with vaccines. This book is useful for graduate, post-graduate students of pharmaceutical sciences, and scientists in pharmacology research and drug development. |
| npj systems biology and applications impact factor: Biocomputing 2023 - Proceedings Of The Pacific Symposium Russ B Altman, Lawrence Hunter, Marylyn D Ritchie, Tiffany A Murray, Teri E Klein, 2022-11-24 The Pacific Symposium on Biocomputing (PSB) 2023 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2023 will be held on January 3-7, 2023 in Kohala Coast, Hawaii. Tutorials and workshops will be offered prior to the start of the conference.PSB 2023 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's 'hot topics.' In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field. |
| npj systems biology and applications impact factor: Hacking Darwin Jamie Metzl, 2019-04-23 A gifted and thoughtful writer, Metzl brings us to the frontiers of biology and technology, and reveals a world full of promise and peril. — Siddhartha Mukherjee MD, New York Times bestselling author of The Emperor of All Maladies and The Gene A groundbreaking exploration of genetic engineering and its impact on the future of our species from leading geopolitical expert and technology futurist, Jamie Metzl. At the dawn of the genetics revolution, our DNA is becoming as readable, writable, and hackable as our information technology. But as humanity starts retooling our own genetic code, the choices we make today will be the difference between realizing breathtaking advances in human well-being and descending into a dangerous and potentially deadly genetic arms race. Enter the laboratories where scientists are turning science fiction into reality. In this captivating and thought-provoking nonfiction science book, Jamie Metzl delves into the ethical, scientific, political, and technological dimensions of genetic engineering, and shares how it will shape the course of human evolution. Cutting-edge insights into the field of genetic engineering and its implications for humanity's future Explores the transformative power of genetic technologies and their potential to reshape human life Examines the ethical considerations surrounding genetic engineering and the choices we face as a species Engaging narrative that delves into the scientific breakthroughs and real-world applications of genetic technologies Provides a balanced perspective on the promises and risks associated with genetic engineering Raises thought-provoking questions about the future of reproduction, human health, and our relationship with nature Drawing on his extensive background in genetics, national security, and foreign policy, Metzl paints a vivid picture of a world where advancements in technology empower us to take control of our own evolution, but also cautions against the pitfalls and ethical dilemmas that could arise if not properly managed. Hacking Darwin is a must-read for anyone interested in the intersection of science, technology, and humanity's future. |
| npj systems biology and applications impact factor: Biocomputing 2022 - Proceedings Of The Pacific Symposium Russ B Altman, A Keith Dunker, Lawrence Hunter, Marylyn D Ritchie, Tiffany A Murray, Teri E Klein, David Baker, 2021-11-29 The Pacific Symposium on Biocomputing (PSB) 2022 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2022 will be held on January 3 - 7, 2022 in Kohala Coast, Hawaii. Tutorials and workshops will be offered prior to the start of the conference.PSB 2022 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's 'hot topics.' In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field. |
| npj systems biology and applications impact factor: Semantic AI in Knowledge Graphs Sanju Tiwari, Fernando Ortiz Rodriguez, Sarra Ben Abbes, Patience Usoro Usip, Rim Hantach, 2023-08-21 Recent combinations of semantic technology and artificial intelligence (AI) present new techniques to build intelligent systems that identify more precise results. Semantic AI in Knowledge Graphs locates itself at the forefront of this novel development, uncovering the role of machine learning to extend the knowledge graphs by graph mapping or corpus-based ontology learning. Securing efficient results via the combination of symbolic AI and statistical AI such as entity extraction based on machine learning, text mining methods, semantic knowledge graphs, and related reasoning power, this book is the first of its kind to explore semantic AI and knowledge graphs. A range of topics are covered, from neuro-symbolic AI, explainable AI and deep learning to knowledge discovery and mining, and knowledge representation and reasoning. A trailblazing exploration of semantic AI in knowledge graphs, this book is a significant contribution to both researchers in the field of AI and data mining as well as beginner academicians. |
| npj systems biology and applications impact factor: The Mathematical Biology of Diatoms Janice L. Pappas, 2023-04-18 THE MATHEMATICAL BIOLOGY OF DIATOMS This book contains unique, advanced applications using mathematics, algorithmic techniques, geometric analysis, and other computational methods in diatom research. Historically, diatom research has centered on taxonomy and systematics. While these topics are of the utmost importance, other aspects of this important group of unicells have been increasingly explored in the biological sciences. While mathematical applications are still rare, they are starting take hold and provide an extensive avenue of new diatom research, including applications in multidisciplinary fields. The work contained in this volume is an eclectic mix of analytical studies on diatoms. Mathematical treatment of the various biological disciplines covered in this book range from implicit, but succinct studies to more elaborate detailed computational studies. Topics include growth models, nanostructure, nanoengineering, cell growth, araphid diatoms, valve ontogeny, diatom metabolism, diatom motility, synchronization, diatom kinematics, photonics, biogenic sensors, photochemistry, diatom light response, colony growth, siliceous unicells, algal kinetics, diatom structure, diatom imaging, functional morphology, geometric structure, biomineralization, high-resolution imaging, non-destructive imaging, and 3D structure. This wide-ranging volume provides an introductory as well as an advanced treatment of recent interests in diatom research. The mathematical research in this volume may be applicable to studies of other unicells, biomechanics, biological processes, physio-chemical analyses, or nanoscience. |
| npj systems biology and applications impact factor: Rethinking Cancer Bernhard Strauss, Marta Bertolaso, Ingemar Ernberg, Mina J. Bissell, 2021-04-27 Leading scientists argue for a new paradigm for cancer research, proposing a complex systems view of cancer supported by empirical evidence. Current consensus in cancer research explains cancer as a disease caused by specific mutations in certain genes. After dramatic advances in genome sequencing, never before have we known so much about the individual cancer cell--and yet never before has it been so unclear what to do with this knowledge. In this volume, leading researchers argue for a new theory framework for understanding and treating cancer. The contributors propose a complex systems view of cancer, presenting conceptual building blocks for a new research paradigm supported by empirical evidence. The contributors first discuss the new research framework in terms of theoretical foundations and then take up the relevance of a systems approach, reviewing such topics as nonlinearity, recurrence after treatment, the cellular attractor concept, network theory, and non-coding DNA--the dark matter of our genome. They address the temporality of cancer progression, drawing on evolutionary theory and clinical experience. Finally, they cover the dominant role of the tissue microenvironment in cancer, analyzing topics including altered metabolic pathways, the disease-defining influence on metastasis, and the interconnectedness of different environmental niches across levels of organization. |
| npj systems biology and applications impact factor: RAS: Past, Present, and Future , 2022-01-29 Advances in Cancer Research, volume 153 provides a timely review of the biology, biochemistry, and current approaches to therapeutically target the RAS oncoprotein, the most frequently mutated oncogene family in human cancers. 2021 saw the approval of the first direct RAS inhibitor (sotorasib) for use in treating non-small cell lung cancers harboring KRAS(G12C) mutations. The successful approval and use of this drug highlights that the once undruggable RAS is indeed pharmacologically tractable. This volume provides an overview of efforts to develop additional approaches to therapeutically target oncogenic RAS. In addition, the reader will find excellent reviews on the history and research efforts to understand the biochemistry and oncogenic activity of RAS in human cancers. - Overview of the history and development of efforts to pharmacologically inhibit RAS. - Discussion of the biochemistry and biology of different RAS mutant proteins and how this might be effectively leveraged in the development of anti-RAS therapies. - Up-to-date reviews of the cutting-edge approaches to develop new anti-RAS pharmacologics. |
| npj systems biology and applications impact factor: Decoding Non-Coding RNA Implicated in Cancer Cell Survival & Growth Modulation Ramkrishna Mitra, Wei Jiang, 2022-06-03 |
| npj systems biology and applications impact factor: Senescence, Senotherapeutics and Mitochondria , 2023-07-14 Senescence, Senotherapeutics and Mitochondria, Volume 136 offers updates on this unique topics, with chapters covering Cellular Senescence in Aging: Molecular Basis, Implications and Therapeutic Interventions, Mitochondria-associated Cellular Senescence Mechanisms: Biochemical and Pharmacological Perspectives, Mitochondria in cell senescence: Friend or Foe?, The role of mitochondria and mitophagy in cell senescence, Small molecules targeting mitochondrial dysfunction for potential senotheraputics, Senolytic and senomorphic interventions to defy senescence-associated mitochondrial dysfunction, Mitochondrial targeting peptides and probes, Mitochondria-derived peptides in healthy ageing and therapy of age-related diseases, and much more. Other sections cover Targeting of mitostasis-proteostasis axis by antioxidant polysaccharides in neurodegeneration, Phytotherapeutic targeting of the mitochondria in neurodegenerative disorders, Melatonin as mitochondria-targeted drugs, Coenzyme Q-related compounds to maintain healthy mitochondria during aging, Changing ROS, NAD and AMP: a path to longevity via mitochondrial therapeutics, and more. - Updates on how mitochondria are closely related to the survival of senescent cells using either mitochondria-targeted senolytic or redox modulator senomorphic strategies - Differentiates itself from other books with its multidisciplinary perspectives and multidimensional clinical approaches - Offers a novel perspective on both the basic and clinical sciences for a wide group of well-established academicians, students and researchers in medicinal chemistry, gerontology, geriatrics, oncology, pharmacology, pathology, bioinformatics, sports science and nutritional sciences |
| npj systems biology and applications impact factor: In Silico Drug Design Kunal Roy, 2019-02-12 In Silico Drug Design: Repurposing Techniques and Methodologies explores the application of computational tools that can be utilized for this approach. The book covers theoretical background and methodologies of chem-bioinformatic techniques and network modeling and discusses the various applied strategies to systematically retrieve, integrate and analyze datasets from diverse sources. Other topics include in silico drug design methods, computational workflows for drug repurposing, and network-based in silico screening for drug efficacy. With contributions from experts in the field and the inclusion of practical case studies, this book gives scientists, researchers and R&D professionals in the pharmaceutical industry valuable insights into drug design. - Discusses the theoretical background and methodologies of useful techniques of cheminformatics and bioinformatics that can be applied for drug repurposing - Offers case studies relating to the in silico modeling of FDA-approved drugs for the discovery of antifungal, anticancer, antiplatelet agents, and for drug therapies against diseases - Covers tools and databases that can be utilized to facilitate in silico methods for drug repurposing |
| npj systems biology and applications impact factor: Blood-Brain Barrier , 2024-07-20 Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. - Provides the latest information on blood-brain barrier research - Offers outstanding and original reviews on a range ofblood-brain barrier research topics - Serves as an indispensable reference for researchers and students alike |
| npj systems biology and applications impact factor: Advances in Applied Microbiology , 2021-08-03 Advances in Applied Microbiology, Volume 116 continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas relating to the topic of microbiology, with this release focusing on the lipid production by oleaginous yeasts. - Contains contributions from leading authorities in the field - Informs and updates on all the latest developments in the field of microbiology - Includes discussions on the role of specific molecules in pathogen life stages, interactions, and much more |
| npj systems biology and applications impact factor: Multilayer Networks: Analysis and Visualization Manlio De Domenico, 2022-03-31 The adoption of multilayer analysis techniques is rapidly expanding across all areas of knowledge, from social sciences (the first facing the complexity of such structures, decades ago) to computer science, from biology to engineering. However, until now, no book has dealt exclusively with the analysis and visualization of multilayer networks. Multilayer Networks: Analysis and Visualization provides a guided introduction to one of the most complete computational frameworks, named muxViz, with introductory information about the underlying theoretical aspects and a focus on the analytical side. Dozens of analytical scripts and examples to use the muxViz library in practice, by means of the Graphical User Interface or by means of the R scripting language, are provided. In addition to researchers in the field of network science, as well as practitioners interested in network visualization and analysis, this book will appeal to researchers without strong technical or computer science background who want to learn how to use muxViz software, such as researchers from humanities, social science and biology: audiences which are targeted by case studies included in the book. Other interdisciplinary audiences include computer science, physics, neuroscience, genetics, urban transport and engineering, digital humanities, social and computational social science. Readers will learn how to use, in a very practical way (i.e., without focusing on theoretical aspects), the algorithms developed by the community and implemented in the free and open-source software muxViz. The data used in the book is available on a dedicated (open and free) site. |
| npj systems biology and applications impact factor: Point Particles to Capture Polarized Embryonic Cells & Cold Pools in the Atmosphere Silas Boye Nissen, 2020-08-31 Part 1: How are the incredible diversity and robustness compatible with animal morphologies? Based on apical-basal and planar cell polarities’ ubiquity, I suggest a 3D mathematical model: Point particles represent cells having zero, one, or two unit-arrows representing polarities. I test the model abilities on preimplantation development, sea urchin gastrulation, mammalian neurulation, organoid folding, and tubulogenesis. I find that a minimal, versatile toolbox, including cellular polarities, captures the emergence of diverse and robust animal morphologies. Part 2: How are deep convective events spatially organized in the tropical atmosphere? Here, I test the importance of atmospheric cold pools for organizing convection. I suggest a 2D mathematical model: Points expand into circles representing cold pools. When circles meet, a convective event occurs, and a new circle forms. I find this model captures convective scale increase and initial stages of convective self-aggregation. The latter is crucial due to its link to tropical cyclogenesis. |
| npj systems biology and applications impact factor: Climate Change and Soil Microorganisms for Environmental Sustainability Meenu Saraf, |
| npj systems biology and applications impact factor: Biocomputing 2020 - Proceedings Of The Pacific Symposium Russ B Altman, A Keith Dunker, Lawrence Hunter, Marylyn D Ritchie, Tiffany A Murray, Teri E Klein, 2019-11-28 The Pacific Symposium on Biocomputing (PSB) 2020 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2020 will be held on January 3 -7, 2020 in Kohala Coast, Hawaii. Tutorials and workshops will be offered prior to the start of the conference.PSB 2020 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's 'hot topics.' In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field. |
| npj systems biology and applications impact factor: Cell Signaling Adeeb Shehzad, 2025-04-17 This book provides a comprehensive understanding of cell signaling, molecular interactions, and their implications for human health and diseases. It introduces fundamental principles underlying cell communication through signaling molecules and their diverse transmission and reception mechanisms, highlighting their role in intercellular communication through voltage- and ion-gated channels, immunological and neuron synapses, and rhinovirus–receptor interaction involved in pathogenesis and disease development. Toward the end, the book highlights the profound implications of altered cell signaling pathways in the inflammation and immune response followed by the progression of various disorders, including cancer, endocrine disorders, and neurological illnesses. It explores the diagnostic and therapeutic implications of cell signaling in targeted therapies, highlighting advanced techniques for detecting signaling molecules and innovative therapeutic approaches to inspire new developments in precision medicine. It serves as an important resource for academics, students, and professionals in the fields of cell biology and biomedical sciences. Key Features: Provides in-depth understanding of cell signaling, exploring its complexities and impact on human health and disease Introduces fundamental principles of cell communication, emphasizing the different signaling molecules and their various transmission pathways Focuses on complex structures and functions of receptors, highlighting their essential role in intercellular communication and regulating cellular behavior Examines the molecular aspects of cell surface adhesion receptors, elucidating protein–protein interactions, signaling cascades, and enzyme–substrate interactions Discusses the impact of cell signaling on inflammation, cancer, and endocrine and neurological disorders |
| npj systems biology and applications impact factor: Boolean Networks as Predictive Models of Emergent Biological Behaviors Jordan C. Rozum, Colin Campbell, Eli Newby, Fatemeh Sadat Fatemi Nasrollahi, Réka Albert, 2024-03-28 Interacting biological systems at all organizational levels display emergent behavior. Modeling these systems is made challenging by the number and variety of biological components and interactions – from molecules in gene regulatory networks to species in ecological networks – and the often-incomplete state of system knowledge, such as the unknown values of kinetic parameters for biochemical reactions. Boolean networks have emerged as a powerful tool for modeling these systems. This Element provides a methodological overview of Boolean network models of biological systems. After a brief introduction, the authors describe the process of building, analyzing, and validating a Boolean model. They then present the use of the model to make predictions about the system's response to perturbations and about how to control its behavior. The Element emphasizes the interplay between structural and dynamical properties of Boolean networks and illustrates them in three case studies from disparate levels of biological organization. |
| npj systems biology and applications impact factor: Computational Physiology Kimberly J. McCabe, 2022-06-09 This open access volume compiles student reports from the 2021 Simula Summer School in Computational Physiology. Interested readers will find herein a number of modern approaches to modeling excitable tissue. This should provide a framework for tools available to model subcellular and tissue-level physiology across scales and scientific questions. In June through August of 2021, Simula held the seventh annual Summer School in Computational Physiology in collaboration with the University of Oslo (UiO) and the University of California, San Diego (UCSD). The course focuses on modeling excitable tissues, with a special interest in cardiac physiology and neuroscience. The majority of the school consists of group research projects conducted by Masters and PhD students from around the world, and advised by scientists at Simula, UiO and UCSD. Each group then produced a report that addreses a specific problem of importance in physiology and presents a succinct summary of the findings. Reports may not necessarily represent new scientific results; rather, they can reproduce or supplement earlier computational studies or experimental findings. Reports from eight of the summer projects are included as separate chapters. The fields represented include cardiac geometry definition (Chapter 1), electrophysiology and pharmacology (Chapters 2–5), fluid mechanics in blood vessels (Chapter 6), cardiac calcium handling and mechanics (Chapter 7), and machine learning in cardiac electrophysiology (Chapter 8). |
| npj systems biology and applications impact factor: Cryptic Enzymes and Moonlighting Proteins Helen Irving, Chris Gehring, Aloysius Wong, 2025-04-24 Cryptic Enzymes and Moonlighting Proteins, a new volume in the Foundations and Frontiers in Enzymology series, offers a thorough overview of cryptic enzymes and moonlighting proteins in signaling cascades. In early chapters, leading international contributors discuss evolutionary considerations for moonlighting proteins, moonlighting interactions in the extracellular matrix, eukaryotic moonlighting proteins, modulating, moonlighting kinases, moonlighting proteins in neurobiology signaling, metabolic enzymes moonlighting as RNA binding and regulatory proteins. Later, methods-driven chapters discuss practical aspects of identifying hidden moonlighting domains in proteins, computational approaches and bioinformatic tools for the identification of cryptic enzymes, establishing cryptic enzyme interactomes, and assessing contributions of moonlighting proteins to signal cascades.The book also explores recent advances in research and brings together an array of information across different fields to enable better targeting of these exciting proteins and their interactomes. With a clear focus on the role of moonlighting and cryptic enzymes in signal transduction, users will find examples of cryptic enzymes across species, as well as those in human healthy biology and pathogenesis. - Covers recent advances in our understanding of cryptic moonlighting proteins in signal cascades, highlighting and examining key themes across disciplines - Empowers researchers to better target cryptic enzymes and moonlighting proteins and their interactomes. - Features chapter contributions from international leaders in the field |
| npj systems biology and applications impact factor: Pharmacogenetic biomarkers for chemotherapy-induced adverse drug reactions Niclas Björn, 2019-11-20 Cancer is a serious disease expected to be the world-leading cause of death in the 21st century. The use of harsh chemotherapies is motivated and accepted but, unfortunately, is often accompanied by severe toxicity and adverse drug reactions (ADRs). These occur because the classical chemotherapies’ common modes of action effectively kill and/or reduce the growth rate not only of tumour cells, but also of many other rapidly dividing healthy cells in the body. There are also considerable interindividual differences in ADRs, even between patients with similar cancers and disease stage treated with equal doses; some experience severe to life-threatening ADRs after one dose, leading to treatment delays, adjustments, or even discontinuation resulting in suboptimal treatment, while others remain unaffected through all treatment cycles. Being able to predict which patients are at high or low risk of ADRs, and to adjust doses accordingly before treatment, would probably decrease toxicity and patient suffering while also increasing treatment tolerability and effects. In this thesis, we have used next-generation sequencing (NGS) and bioinformatics for the prediction of myelosuppressive ADRs in lung and ovarian cancer patients treated with gemcitabine/carboplatin and paclitaxel/carboplatin. Paper I shows that ABCB1 and CYP2C8 genotypes have small effects inadequate for stratification of paclitaxel/carboplatin toxicity. This supports the transition to whole-exome sequencing (WES) and whole-genome sequencing (WGS). Papers II and IV, respectively, use WES and WGS, and demonstrate that genetic variation in or around genes involved in blood cell regulation and proliferation, or genes differentially expressed at chemotherapy exposure, can be used in polygenic prediction models for stratification of gemcitabine/carboplatininduced myelosuppression. Paper III reassuringly shows that WES and WGS are concordant and mostly yield comparable genotypes across the exome. Paper V proves that single-cell RNA sequencing of hematopoietic stem cells is a feasible method for elucidating differential transcriptional effects induced as a response to in vitro chemotherapy treatment. In conclusion, our results supports the transition to genome-wide approaches using WES, WGS, and RNA sequencing to establish polygenic models that combine effects of multiple pharmacogenetic biomarkers for predicting chemotherapy-induced ADRs. This approach could be applied to improve risk stratification and our understanding of toxicity and ADRs related to other drugs and diseases. We hope that our myelosuppression prediction models can be refined and validated to facilitate personalized treatments, leading to increased patient wellbeing and quality of life. |
| npj systems biology and applications impact factor: p53 in Breast Cancer Manzoor Ahmad Mir, 2024-12-24 p53 in Breast Cancer: Molecular Mechanisms, Clinical Implications, and Therapeutic Targets comprehensively reviews the role of p53 in breast cancer development, progression, and treatment. It explores the multifaceted functions of p53, from its fundamental connection to breast cancer and pathway mechanisms to its influence on cancer metabolism and the impact of mutational alterations. The initial chapters discuss the complex landscape of p53's involvement in cancer metabolism, the ramifications of its mutations, and its crucial role as a tumor suppressor. The subsequent chapters review the regulatory functions of p53 in cell death, DNA repair, genomic stability, and cell cycle dynamics, highlighting its interactions with transcription factors, DNA repair enzymes, and family members p63 and p73. It further reviews the regulation of mutant p53 via post-translational modifications and delves into the approaches to combat mutated p53, highlighting targeted therapies and efforts to overcome chemoresistance. The chapters also address the role of p53 biomarkers in diagnosis and prognosis, the optimization of treatment responses, and the impact of nutrition on p53 activity. This book is an important resource for oncology and molecular biology researchers. Key Features Provides a thorough examination of the p53 gene and its crucial involvement in breast cancer. Explores the critical implications of mutational alterations in p53 on the development and progression of breast cancer. Examines the role of p53 in managing apoptosis and contributing to DNA repair and genomic stability. Discusses the complex interactions of p53 with transcription factors, DNA repair enzymes, p63, and p73. Highlights the role of p53 as a biomarker in diagnosing and predicting breast cancer prognosis. |
| npj systems biology and applications impact factor: Medicinal and Aromatic Plants Lakhan Kumar, Navneeta Bharadvaja, Ram Singh, Raksha Anand, 2024-06-29 Due to complex phytochemical components and associated beneficial properties, numerous medicinal and aromatic plants, in whole or parts, have been used for nutritional purposes or the treatment of various diseases and disorders in humans and animals. Essential oils from medicinal and aromatic plants (MAPs) have been exploited for product formulations of pharmaceuticals, cosmetics, food and beverage, colorants, biopesticides, and several other utility chemicals of industrial importance. There is scientific evidence of many medicinal plant extracts possessing immunomodulatory, immunostimulatory, antidiabetic, anticarcinogenic, antimicrobial, and antioxidant properties, thus demonstrating their traditional use in popular medicine. With the advent of modern technology, the exploitation of natural resources has exponentially increased in order to fulfill the demand of an increased human population with improved quality of life. The traditional agriculture and production-based supply of commodities is inadequate to meet the current demand. Biotechnological approaches are gaining importance to bridge the gaps in demand and supply. In the proposed book, medicinal and aromatic plant-based secondary metabolites have been discussed in terms of their therapeutic potential and industrial relevance. To discuss the qualitative and quantitative analysis of a range of medicinal and aromatic plants-based secondary metabolites (SMs), bioprocess development for their extraction and bioseparation, a brief overview of their industrial relevance, various tissue culturing strategies, biotechnological approaches to enhance production, scale-up strategies, management of residual biomass post extraction of target SMs is central to the idea of the proposed book. A section will explore the verticals mentioned above. In the next section, the book addresses the approaches for conserving and improving medicinal and aromatic plant genetic resources. In the third section, approaches to managing the post-harvest crop residue and secondary metabolites extracted plant biomass will be thoroughly discussed. The recent integration of artificial intelligence to improve medicinal and aromatic plant research at several levels, including the development and employment of computational approaches to enhance secondary metabolite production, tissue culture, drug design and discovery, and disease treatment, will be included in the fourth section. The book summarizes current research status, gaps in knowledge, agro-industrial potential, waste or residual plant biomass management, conservation strategies, and computational approaches in the area of medicinal and aromatic plants with an aim to translate biotechnological interventions into reality. |
| npj systems biology and applications impact factor: Inflammatory Bowel Disease and Gut Microbiota Neeraj Mishra, Sumel Ashique, Ashish Garg, 2025-07-15 This new volume delves into the extensive new research on inflammatory bowel disease (IBD) and gut microbiota that has led to effective therapeutic interventions. Highlighting novel methodologies and innovative treatment approaches, the book provides a comprehensive investigation of IBD, exploring the significance of gut microbiota and investigating the fundamental role of microbial imbalances in the initiation and progression of inflammatory processes as well as the prominent therapeutic consequences of restoring microbial homeostasis. From nanoparticle-based drug delivery systems that advance the bioavailability of the medicament to the use of bio-nanosensors for early detection of disease, the book covers a broad spectrum of inventions that hold potential for revolutionizing IBD treatment. The authors look at the impact of nutraceuticals, probiotics, prebiotics, functional foods, oral siRNA-based nanomedicine, and other novel drug delivery systems on gut microbiota for the management of IBD. The book also explores the role of reactive oxygen species (ROSs), superoxide dismutases (SODs), and inflammation in association with gut microbiota and IBD. |
| npj systems biology and applications impact factor: Old Yeasts Cândida Lucas, Célia Pais, 2017-12-13 Yeast-based biotechnology traditionally regards the empirical production of fermented drinks and leavened bread, processes which surprisingly keep posing challenges and fuelling research. But yeasts nowadays also provide amenable cell factories, producing bulk and fine chemicals and molecules, and are increasingly used as tools in processes as diverse as food preservation or bioremediation. Importantly, yeasts are excellent models of cell and molecular biology for higher eukaryotes, including humans, contributing with key discoveries to understand processes and diseases. All taken, yeast-related business is worth billions, critically contributing to the economical welfare of many differently developed countries. This book provides some insights into aspects of yeast science and biotechnology less frequently addressed in the literature but nonetheless decisive to improve knowledge and, accordingly, boost up yeast-based innovation. |
| npj systems biology and applications impact factor: Deep Learning in Genetics and Genomics Khalid Raza, 2024-11-28 Deep Learning in Genetics and Genomics: Vol. 2 (Advanced Applications) delves into the Deep Learning methods and their applications in various fields of studies, including genetics and genomics, bioinformatics, health informatics and medical informatics generating the momentum of today's developments in the field. In 25 chapters this title covers advanced applications in the field which includes deep learning in predictive medicines), analysis of genetic and clinical features, transcriptomics and gene expression patterns analysis, clinical decision support in genetic diagnostics, deep learning in personalised genomics and gene editing, and understanding genetic discoveries through Explainable AI. Further, it also covers various deep learning-based case studies, making this book a unique resource for wider, deeper, and in-depth coverage of recent advancement in deep learning based approaches. This volume is not only a valuable resource for health educators, clinicians, and healthcare professionals but also to graduate students of genetics, genomics, biology, biostatistics, biomedical sciences, bioinformatics, and interdisciplinary sciences. - Embraces the potential that deep learning holds for understanding genome biology - Encourages further advances in this area, extending to all aspects of genomics research - Provides Deep Learning algorithms in genetic and genomic research |
| npj systems biology and applications impact factor: Encyclopedia of Happiness, Quality of Life and Subjective Wellbeing Hilke Brockmann, Roger Fernandez-Urbano, 2024-08-06 This comprehensive Encyclopedia delves into the underpinnings, approaches, and recent advancements in the dynamic global landscape of happiness and wellbeing research. Laying out the foundational concepts and disciplinary perspectives in the field, international leading and diverse authors survey the determinants and mechanisms which are associated with happiness, quality of life and subjective wellbeing. This title contains one or more Open Access entries. |
| npj systems biology and applications impact factor: From Theory of Knowledge Management to Practice Fausto Pedro García Márquez, René Vinicio Sánchez Loja, 2024-01-31 From Theory of Knowledge Management to Practice is a collaborative compilation featuring contributions from various authors. The book amalgamates analytical principles with the practical aspects of knowledge management in the business realm. Its unique contribution lies in bridging the gap between engineering/technology disciplines and the organizational, administrative, and planning dimensions of knowledge management. This integration is particularly valuable when viewed in conjunction with other sub-disciplines like economics, finance, marketing, and decision and risk analysis, among others. The book not only introduces but also illustrates knowledge management theories through practical case studies. These case studies showcase significant outcomes across different sectors, drawing on diverse real-world scenarios. The theoretical framework is accompanied by relevant analytical techniques, adopting a progressive approach that transitions from basic concepts to intricate and dynamic decision-making processes involving multiple data points, including big data and extensive datasets. The integration of computational techniques, dynamic analysis, probabilistic methods, and mathematical optimization further enhances the book's utility, offering expert support for the analysis of multi-criteria decision-making problems characterized by specific constraints and requirements. |
| npj systems biology and applications impact factor: An Introduction to Computational Systems Biology Karthik Raman, 2021-05-30 This book delivers a comprehensive and insightful account of applying mathematical modelling approaches to very large biological systems and networks—a fundamental aspect of computational systems biology. The book covers key modelling paradigms in detail, while at the same time retaining a simplicity that will appeal to those from less quantitative fields. Key Features: A hands-on approach to modelling Covers a broad spectrum of modelling, from static networks to dynamic models and constraint-based models Thoughtful exercises to test and enable understanding of concepts State-of-the-art chapters on exciting new developments, like community modelling and biological circuit design Emphasis on coding and software tools for systems biology Companion website featuring lecture videos, figure slides, codes, supplementary exercises, further reading, and appendices: https://ramanlab.github.io/SysBioBook/ An Introduction to Computational Systems Biology: Systems-Level Modelling of Cellular Networks is highly multi-disciplinary and will appeal to biologists, engineers, computer scientists, mathematicians and others. |
| npj systems biology and applications impact factor: Computational Methods for Rational Drug Design Mithun Rudrapal, 2025-02-05 Comprehensive resource covering computational tools and techniques for the development of cost-effective drugs to combat diseases, with specific disease examples Computational Methods for Rational Drug Design covers the tools and techniques of drug design with applications to the discovery of small molecule-based therapeutics, detailing methodologies and practical applications and addressing the challenges of techniques like AI/ML and drug design for unknown receptor structures. Divided into 23 chapters, the contributors address various cutting-edge areas of therapeutic importance such as neurodegenerative disorders, cancer, multi-drug resistant bacterial infections, inflammatory diseases, and viral infections. Edited by a highly qualified academic with significant research contributions to the field, Computational Methods for Rational Drug Design explores topics including: Computer-assisted methods and tools for structure- and ligand-based drug design, virtual screening and lead discovery, and ADMET and physicochemical assessments In silico and pharmacophore modeling, fragment-based design, de novo drug design and scaffold hopping, network-based methods and drug discovery Rational design of natural products, peptides, enzyme inhibitors, drugs for neurodegenerative disorders, anti-inflammatory therapeutics, antibacterials for multi-drug resistant infections, and antiviral and anticancer therapeutics Protac and protide strategies in drug design, intrinsically disordered proteins (IDPs) in drug discovery and lung cancer treatment through ALK receptor-targeted drug metabolism and pharmacokinetics Helping readers seamlessly navigate the challenges of drug design, Computational Methods for Rational Drug Design is an essential reference for pharmaceutical and medicinal chemists, biochemists, pharmacologists, and phytochemists, along with molecular modeling and computational drug discovery professionals. |
| npj systems biology and applications impact factor: Open AI and Computational Intelligence for Society 5.0 Pandey, Rajiv, Srivastava, Nidhi, Prasad, Rajesh, Prasad, Jayashree, Garcia, Manuel B., 2024-11-29 As technology rapidly advances, the complexity of societal challenges grows, necessitating intelligent solutions that can adapt and evolve. However, developing such solutions requires a deep understanding of computational intelligence (CI) and its application in addressing real-world problems. Moreover, ethical considerations surrounding AI, such as bias and accountability, are crucial to ensure responsible development and deployment of intelligent systems. Open AI and Computational Intelligence for Society 5.0 offers a comprehensive exploration of CI, providing insights into intelligent systems' theory, design, and application. This book is a practical guide for scientists, engineers, and researchers seeking to develop thoughtful solutions for complex societal issues. Integrating disruptive technologies and frameworks illuminates the path toward creating intelligent machines collaborating with humans to enhance problem-solving and improve quality of life. |
| npj systems biology and applications impact factor: Bioinformatics for Plant Research and Crop Breeding Jen-Tsung Chen, 2024-10-28 Explore and advance bioinformatics and systems biology tools for crop breeding programs in this practical resource for researchers Plant biology and crop breeding have produced an immense amount of data in recent years, from genomics to interactome and beyond. Bioinformatics tools, which aim at analyzing the vast quantities of data produced by biological research and processes, have developed at a rapid pace to meet the challenges of this vast data trove. The resulting field of bioinformatics and systems biology is producing increasingly rich and transformative research. Bioinformatics for Plant Research and Crop Breeding offers an overview of this field, its recent advances, and its wider applications. Drawing on a range of analytical and data-science tools, its foundation on an in-silico platform acquired multi-omics makes it indispensable for scientists and researchers alike. It promises to become ever more relevant as new techniques for generating and organizing data continue to transform the field. Bioinformatics for Plant Research and Crop Breeding readers will also find: A focus on emerging trends in plant science, sustainable agriculture, and global food security Detailed discussion of topics including plant diversity, plant stresses, nanotechnology in agriculture, and many others Applications incorporating artificial intelligence, machine learning, deep learning and more Bioinformatics for Plant Research and Crop Breeding is ideal for researchers and scientists interested in the potential of OMICs, and bioinformatic tools to aid and develop crop improvement programs. |
| npj systems biology and applications impact factor: Artificial Intelligence in Urology Andrew J Hung, 2024-10-19 Artificial Intelligence in Urology: Present and Future summarizes the cutting-edge development and adoption of Artificial Intelligence (AI) technologies in urology. The book explores barriers that prevent the further adoption of AI technologies, provides ethical considerations, and investigates the future role AI is expected to play. In addition, it includes applications of AI technology in the diagnosis and treatment of cancers (prostate, bladder, and more) and kidney stones, and in both adult and pediatric care. This is the perfect reference for researchers developing AI technologies for clinical applications and for clinicians who aim to effectively adopt AI technologies to solve clinical questions. - Describes the state-of-the-art of AI applications in urology by leading experts in the field - Provides a comprehensive review of how different strategies in AI are utilized to solve a wide range of clinical problems—from diagnosis, treatment, and prognostication of urologic diseases - Comprises contents that can be used as a springboard to allow readers to adopt AI technologies in their field of study/practice |
| npj systems biology and applications impact factor: The Aesthetics of Scientific Experiments Milena Ivanova, Alice Murphy, 2023-06-16 The relationship between aesthetics and science has begun to generate substantial interest. However, for the most part, the focus has been on the beauty of theories, and other aspects of scientific practice have been neglected. This book offers a novel perspective on aesthetics in experimentation via ten original essays from an interdisciplinary group comprised of philosophers, historians of science and art, and artists. The collection provides an analysis of the concept of beauty in the evaluation of experiments. What properties do practising experimenters value? How have the aesthetic properties of scientific experiments changed over the years? Secondly, the volume looks at the role that aesthetic factors, including negative values such as ugliness, as well as experiences of the sublime and the profound, play in the construction of an experiment and its reception. Thirdly, the chapters provide in-depth historical case studies from the Royal Society, which also allows for a study of the depiction of scientific experiment in artworks, as well as contemporary examples from the Large Hadron Collider and cases of experiments designed by artificial intelligence. Finally, it offers an exploration of the commonalities between how we learn from experiments on the one hand and the cognitive value of artworks on the other. The Aesthetics of Scientific Experiments will be of interest to researchers and advanced students working in philosophy and history of science, philosophy and history of art, as well as practising scientists and science communicators. |
如何评价 Nature 出版社的合作期刊计划（Nature Partner Journal
总之国内只认可Nature打头的那一票Sister Journals（不包括 Nature Communications 这个庶子）为大子刊，Nature Communications一般认为略低于JACS而与Angew/ AM 持平，NPG Asia Mater定位 …
《自然》杂志为什么有那么多子刊，定位如何？ - 知乎
《自然》杂志为什么有那么多子刊，定位如何？《科学》就始终只有一样。《自然》的商业控股如何，是不是某…
科研圈里有没有nature四大子刊这个说法，网上搜的结果靠谱吗， …
没听过，事实上科研圈是大致这么排名的. 1.nature/science本刊. 2.nature大子刊（比如nature energy、nature catalyst这种…）至于大子刊之间的排名，这个和学科方向有关，比如nature energy、nature …
为什么npj Climate and Atmospheric是中科院一区，但不是top？
Dec 28, 2023 · 知乎，中文互联网高质量的问答社区和创作者聚集的原创内容平台，于 2011 年 1 月正式上线，以「让人们更好的分享知识、经验和见解，找到自己的解答」为品牌使命。知乎凭借认真、专 …
投稿Communications Physics和npj Quantum Materials哪个更好？
May 7, 2023 · 投稿Communications Physics和npj Quantum Materials哪个更好？ 凝聚态理论的工作 投更好的期刊被编辑拒了 这两个之间有些犹豫 不太清楚哪个更好 显示全部 关注者
science或nature系列的文章审稿有多少个阶段？ - 知乎
知乎，中文互联网高质量的问答社区和创作者聚集的原创内容平台，于 2011 年 1 月正式上线，以「让人们更好的分享知识、经验和见解，找到自己的解答」为品牌使命。知乎凭借认真、专业、友善的社区 …
如何看待Nature将于2021年新增子刊Nature Computational …
据报道Nature将于2021年新增三本子刊，分别为Nature Aging, Nature Computational Science与Nature Revie…
Endnote如何导入新的output style（参考文献格式）模板？ - 知乎
已有一个新的参考文献模板，如何将其导入到Endnote中使用？
如何看待 12 月 17 日最新发布的《2020 年中国科学院文献情报中 …
Dec 17, 2020 · npj computational materials 掉到2区有点出乎我的意料。 前段时间一篇投PRL的文章二审被拒，当时还犹豫要不要转投npj computational materials，一来这个杂志同样接受短文，文章结 …
量子信息方面的SCI期刊有哪些？ - 知乎
npj quantum information，关注的不多但看到的文章都挺有意思的，不过发文量也不多。 physical review RESEARCH，再提名一下前几年新出的prr，最近看的挺多的质量好像出奇的高。也 …
如何评价 Nature 出版社的合作期刊计划（Nature Partner Journal
总之国内只认可Nature打头的那一票Sister Journals（不包括 Nature Communications 这个庶子）为大子刊，Nature Communications一般认为略低于JACS而与Angew/ AM 持平，NPG Asia …
《自然》杂志为什么有那么多子刊，定位如何？ - 知乎
《自然》杂志为什么有那么多子刊，定位如何？《科学》就始终只有一样。《自然》的商业控股如何，是不是某…
科研圈里有没有nature四大子刊这个说法，网上搜的结果靠谱吗， …
没听过，事实上科研圈是大致这么排名的. 1.nature/science本刊. 2.nature大子刊（比如nature energy、nature catalyst这种…）至于大子刊之间的排名，这个和学科方向有关，比如nature …
为什么npj Climate and Atmospheric是中科院一区，但不是top？
Dec 28, 2023 · 知乎，中文互联网高质量的问答社区和创作者聚集的原创内容平台，于 2011 年 1 月正式上线，以「让人们更好的分享知识、经验和见解，找到自己的解答」为品牌使命。知乎 …
投稿Communications Physics和npj Quantum Materials哪个更好？
May 7, 2023 · 投稿Communications Physics和npj Quantum Materials哪个更好？ 凝聚态理论的工作 投更好的期刊被编辑拒了 这两个之间有些犹豫 不太清楚哪个更好 显示全部 关注者
science或nature系列的文章审稿有多少个阶段？ - 知乎
知乎，中文互联网高质量的问答社区和创作者聚集的原创内容平台，于 2011 年 1 月正式上线，以「让人们更好的分享知识、经验和见解，找到自己的解答」为品牌使命。知乎凭借认真、专业 …
如何看待Nature将于2021年新增子刊Nature Computational …
据报道Nature将于2021年新增三本子刊，分别为Nature Aging, Nature Computational Science与Nature Revie…
Endnote如何导入新的output style（参考文献格式）模板？ - 知乎
已有一个新的参考文献模板，如何将其导入到Endnote中使用？
如何看待 12 月 17 日最新发布的《2020 年中国科学院文献情报中 …
Dec 17, 2020 · npj computational materials 掉到2区有点出乎我的意料。 前段时间一篇投PRL的文章二审被拒，当时还犹豫要不要转投npj computational materials，一来这个杂志同样接受短 …
量子信息方面的SCI期刊有哪些？ - 知乎
npj quantum information，关注的不多但看到的文章都挺有意思的，不过发文量也不多。 physical review RESEARCH，再提名一下前几年新出的prr，最近看的挺多的质量好像出奇的高。也 …
