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| ncrna types: AGO-Driven Non-Coding RNAs Bibekanand Mallick, 2019-01-24 The 'RNA world' hypothesis that proposed RNA molecules as the first form of genetic material was put forwarded in the late 1980s but got impetus only recently when high-throughput sequencing technologies began unearthing new types of non-coding RNA (ncRNA) transcripts in higher eukaryotes. Till then, research on ncRNAs were primarily confined to transfer RNAs and, ribosomal RNAs, which act as the messengers of the protein synthesis and allow translation of genetic information encoded by DNA into proteins. In recent years, the integration of high-throughput genomic technologies with molecular biology and omics sciences have revolutionized the fields of ncRNA research by identifying the hidden treasures of several new types of ncRNAs encoded in the genomes of several organisms and decrypting their versatile roles in gene expression and epigenetics. Among these, two small endogenous ncRNAs, namely microRNAs (miRNAs) and piwi-interacting RNAs (piRNAs) that drive argonaute (AGO) family of proteins namely Ago and Piwi respectively and silence the expression of genes have geared up molecular and disease biology research in recent years. Both miRNAs and piRNAs are expressed in higher eukaryotes, including human and act as cellular rheostats by regulating the expression of significant fraction of genes encoded in the genomes. The aberrant expressions of these small ncRNAs within the cells cause various abnormalities and diseases including cancer. Manipulating their aberrant expression or function can serve as potential novel diagnostic/prognostic biomarkers and bring in new therapeutic strategies for multiple human diseases. This can be further translated from bench-side to clinic for improving human health. This book captures the essence of the pioneering work of some of the world's leading researchers showcasing the scientific excitements surrounding the evolving regulatory roles of miRNAs and piRNAs highlighting their potential towards the diagnosis and therapeutics of various diseases. The book is geared towards scientists, students, and will particularly appeal to active investigators in RNA biology, molecular biology, cancer research as well as clinicians and will provide them a comprehensive view of recent discoveries and research progresses to utilize miRNAs, piRNAs and their interacting proteins, Ago and Piwi for diagnosis, prognosis and therapeutics of diseases. |
| ncrna types: Non-coding RNA in Plants Rahul Datta, Chintan Kapadia, Subhan Danish, Sachidanand Singh, 2024-11-29 Non-coding RNA in Plants: Modulation and Stress Responses is the first book to present the basics of the importance of long non-coding RNA and its potential in addressing abiotic and biotic stresses. Describing the MiRNA and small RNA and their role in plant development, this book explains the importance of long non-coding RNA in plants, including its significance in virus resistance, its transposable elements, effector trigger immunity, and fungal and bacterial resistance in plants. Non-coding RNA for Modulation and Stress Response in Plants presents the state-of-the-science from its historical foundation through application throughout the lifecycle and production of agricultural and non-agricultural plants. While various coding has been explored within animal science, plant exposition has been minimal. This book is designed to inspire additional research and developments toward improved plant resiliency and production. - Presents foundational information for understanding the importance of long non-coding RNA in plants - Summarizes and illustrates identification and diversity analysis approaches toward Non-coding RNA as regulations - Explores how non-coding RNAs may play a role in the regulation of stress responses by highlighting their biogenesis and mechanisms of action |
| ncrna types: ncRNAs: Mediated Regulation Channapatna S. Prakash, Muhammad Waseem, Sajid Fiaz, 2024-11-04 Non-coding RNAs (ncRNAs) are a class of RNA molecules that do not encode proteins but play pivotal roles in regulating gene expression and cellular processes. Emerging evidence suggests that ncRNAs have evolved as key regulators in mediating adaptive responses to environmental constraints. By modulating gene expression, ncRNAs enable organisms to fine-tune their physiological and cellular processes to maintain homeostasis under different environmental conditions. Understanding the biological function of ncRNAs in response to environmental stimuli is crucial for unraveling the complex regulatory networks that underlie adaptation and survival. This book explores various types of ncRNAs, including microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs), and their involvement in the modulation of gene expression networks in plants to adapt to changing environmental conditions. Additionally, the book discusses the mechanisms by which ncRNAs interact with their target molecules, such as mRNAs and proteins, to exert regulatory effects. This information about nRNA response to environmental stresses - acting as regulators of cellular processes and stress-related signaling pathways for improving crop production - are lying unorganized in different articles of journals and edited books. Therefore, it is time demanding to publish a book dealing with these aspects. The introduction discusses the significance of understanding ncRNA-mediated regulation in the context of adaptation and survival in changing environmental conditions. By providing a comprehensive overview, this sets the stage for the subsequent chapters. Chapters then delve into the role of ncRNAs in epigenetic regulation and transgenerational effects, and explore how ncRNAs participate in shaping the epigenome and influencing heritable gene expression without altering the DNA sequence. This book discusses the implications of ncRNA-mediated epigenetic regulation in adapting to environmental challenges and its potential transgenerational effects. It summarizes key findings and highlights the importance of ncRNA-mediated regulation in responding to environmental constraints, emphasizing the unarguable biological function of ncRNAs and their role as critical regulators in adaptation and survival. |
| ncrna types: Non-coding RNAs for Crop Improvement Kavita Goswami, Temesgen Assefa Gelaw, Neeti Sanan-Mishra, 2025-02-14 This edited book covers all aspects of non-coding RNAs analysis. Non-coding RNAs are critical genetic regulators that have evolved as game-changers in modifying plant responses to stress conditions. The book explores potential relationships between different classes of non-coding RNAs and response of plants to biotic and abiotic stresses. The chapters are organized into three sections. Section 1 provides a basic understanding of the various aspects and roles of RNA silencing. Section 2 includes an overview of the molecular techniques and computational methodologies used for identification and analysis of small RNAs. Discovery timelines are also provided to highlight the significance of next-generation sequencing over time. Section 3 of the book covers the applications of RNAi techniques to improve crops and develop stress-tolerant varieties. This book compiles all available data and computational approaches to analyze non-coding RNAs. It describes the general characteristics, categorization, functional analysis, and advancements in RNAi and its role in developing stress-resilient plants. This book is helpful for students and researchers to understand the role of non-coding RNAs, which opens new insights into next-generation sequencing. It serves as excellent reading material for undergraduate and graduate students studying molecular biology, bioinformatics, agriculture, and environmental sciences. |
| ncrna types: Computational Biology of Non-Coding RNA Xin Lai, Shailendra Gupta, Julio Vera Gonzalez, 2024-12-19 This second edition details a collection of state-of-art methods including identification of novel ncRNAs and their targets, functional annotation and disease association in different biological contexts. Chapters guide readers through an overview of disease-specific ncRNAs, computational methods and workflows for ncRNA discovery, annotation based on high-throughput sequencing data, bioinformatics tools and databases for ncRNA analyses, network-based methods, and kinetic modelling of ncRNA-mediated gene regulation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Computational Biology of Non-Coding RNA: Methods and Protocols, Second Edition aims to ensure successful results in the further study of this vital field. |
| ncrna types: Navigating Non-coding RNA Joanna Sztuba-Solinska, 2023-06-17 Navigating Non-coding RNA: From Biogenesis to Therapeutic Application provides a concise overview of the field of non-coding RNA (ncRNA). Chapters cover the history of discoveries that have occurred in the area of ncRNA, specific types of ncRNA, housekeeping ncRNAs such as ribosomal RNA, transfer RNA, small nuclear RNA and telomerase RNA, regulatory ncRNAs such as microRNA, small interfering RNA, long non-coding RNA and Y RNA. Biogenesis, structure, function, and regulation of each of these are also explored in addition to traditional and cutting-edge methods for the identification, functional characterization and structural characterization of ncRNA. The book also focuses on the different types of epitranscriptomic modifications and their involvement in regulating ncRNA structure, stability and intermolecular interactions in addition to the role of ncRNAs in a range of diseases and potential therapeutic applications. - Covers a wide range of non-coding RNAs, including ribosomal RNA, transfer RNA, telomerase RNA, microRNA, small interfering RNA and circular RNA - Features both traditional and novel methodologies for investigating ncRNA, from microarray and conventional chemical probing to CAGE-seq and computational methods - Includes chapters on ncRNAs in a range of diseases, including cancers, neurological disorders, cardiovascular conditions and infectious illnesses - Discusses novel therapeutic strategies for targeting ncRNAs, including CRISP/Ca9 applications and RNAi-based strategies - Explores the molecular mechanisms and intermolecular interactions of ncRNA |
| ncrna types: Encyclopedia of Bioinformatics and Computational Biology , 2018-08-21 Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics, Three Volume Set combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases |
| ncrna types: Bioinformatics of Non-Coding RNAs with Applications to Biomedicine: Recent Advances and Open Challenges Carlo Maria Croce, Alfredo Ferro, Alessandro Laganà, 2017-01-27 The recent discovery of small and long non-coding RNAs (ncRNAs) has represented a major breakthrough in the life sciences. These molecules add a new layer of complexity to biological processes and pathways by revealing a sophisticated and dynamic interconnected system whose structure is just beginning to be uncovered. Genetic and epigenetic aberrations affecting ncRNA gene sequences and their expression have been linked to a variety of pathological conditions, including cancer, cardiovascular and neurological diseases. Latest advances in the development of high throughput analysis techniques may help to shed light on the complex regulatory mechanisms in which ncRNA molecules are involved. Bioinformatics tools constitute a unique and essential resource for non-coding RNA studies, providing a powerful technology to organize, integrate and analyze the huge amount of data produced daily by wet biology experiments in order to discover patterns, identify relationships among heterogeneous biological elements and formulate functional hypotheses. This Research Topic reviews current knowledge, introduces novel methods, and discusses open challenges of this exciting and innovative field in connection with the most important biomedical applications. It consists of four reviews and six original research and methods articles, spanning the full scope of the Research Topic. |
| ncrna types: Non-coding RNA and addiction Andre Pietrzykowski, Matthew Reilly, Da-Yu Wu, Leonard Lipovich, Marissa A. Ehringer, Jonathan Pollock, |
| ncrna types: Long Noncoding RNAs in Plants Santosh Kumar Upadhyay, 2020-11-13 The growth of human population has increased the demand for improved yield and quality of crops and horticultural plants. However, plant productivity continues to be threatened by stresses such as heat, cold, drought, heavy metals, UV radiations, bacterial and fungal pathogens, and insect pests. Long noncoding RNAs are associated with various developmental pathways, regulatory systems, abiotic and biotic stress responses and signaling, and can provide an alternative strategy for stress management in plants. Long Noncoding RNAs in Plants: Roles in development and stress provides the most recent advances in LncRNAs, including identification, characterization, and their potential applications and uses. Introductory chapters include the basic features and brief history of development of lncRNAs studies in plants. The book then provides the knowledge about the lncRNAs in various important agricultural and horticultural crops such as cereals, legumes, fruits, vegetables, and fiber crop cotton, and their roles and applications in abiotic and biotic stress management. - Includes the latest advances and research in long noncoding RNAs in plants - Provides alternative strategies for abiotic and biotic stress management in horticultural plants and agricultural crops - Focuses on the application and uses of long noncoding RNAs |
| ncrna types: Computational Non-coding RNA Biology Yun Zheng, 2018-09-14 Computational Non-coding RNA Biology is a resource for the computation of non-coding RNAs. The book covers computational methods for the identification and quantification of non-coding RNAs, including miRNAs, tasiRNAs, phasiRNAs, lariat originated circRNAs and back-spliced circRNAs, the identification of miRNA/siRNA targets, and the identification of mutations and editing sites in miRNAs. The book introduces basic ideas of computational methods, along with their detailed computational steps, a critical component in the development of high throughput sequencing technologies for identifying different classes of non-coding RNAs and predicting the possible functions of these molecules. Finding, quantifying, and visualizing non-coding RNAs from high throughput sequencing datasets at high volume is complex. Therefore, it is usually possible for biologists to complete all of the necessary steps for analysis. - Presents a comprehensive resource of computational methods for the identification and quantification of non-coding RNAs - Introduces 23 practical computational pipelines for various topics of non-coding RNAs - Provides a guide to assist biologists and other researchers dealing with complex datasets - Introduces basic computational methods and provides guidelines for their replication by researchers - Offers a solution to researchers approaching large and complex sequencing datasets |
| ncrna types: AGO-Driven Non-Coding RNAs Bibekanand Mallick, 2019-01-20 The 'RNA world' hypothesis that proposed RNA molecules as the first form of genetic material was put forwarded in the late 1980s but got impetus only recently when high-throughput sequencing technologies began unearthing new types of non-coding RNA (ncRNA) transcripts in higher eukaryotes. Till then, research on ncRNAs were primarily confined to transfer RNAs and, ribosomal RNAs, which act as the messengers of the protein synthesis and allow translation of genetic information encoded by DNA into proteins. In recent years, the integration of high-throughput genomic technologies with molecular biology and omics sciences have revolutionized the fields of ncRNA research by identifying the hidden treasures of several new types of ncRNAs encoded in the genomes of several organisms and decrypting their versatile roles in gene expression and epigenetics. Among these, two small endogenous ncRNAs, namely microRNAs (miRNAs) and piwi-interacting RNAs (piRNAs) that drive argonaute (AGO) family of proteins namely Ago and Piwi respectively and silence the expression of genes have geared up molecular and disease biology research in recent years. Both miRNAs and piRNAs are expressed in higher eukaryotes, including human and act as cellular rheostats by regulating the expression of significant fraction of genes encoded in the genomes. The aberrant expressions of these small ncRNAs within the cells cause various abnormalities and diseases including cancer. Manipulating their aberrant expression or function can serve as potential novel diagnostic/prognostic biomarkers and bring in new therapeutic strategies for multiple human diseases. This can be further translated from bench-side to clinic for improving human health. This book captures the essence of the pioneering work of some of the world's leading researchers showcasing the scientific excitements surrounding the evolving regulatory roles of miRNAs and piRNAs highlighting their potential towards the diagnosis and therapeutics of various diseases. The book is geared towards scientists, students, and will particularly appeal to active investigators in RNA biology, molecular biology, cancer research as well as clinicians and will provide them a comprehensive view of recent discoveries and research progresses to utilize miRNAs, piRNAs and their interacting proteins, Ago and Piwi for diagnosis, prognosis and therapeutics of diseases. - Provides a unified cutting-edge resource for both miRNAs and piRNAs, two promising AGO-clade small ncRNAs, their functions and potential applications - Showcase high-throughput technologies and other approaches for discovery of these small ncRNAs and their targets - Unveils the diverse molecular mechanisms by which miRNAs and piRNAs regulate gene expression in animal cells - Showcase recent discoveries on involvement of Argonaute and Piwi proteins in different biological processes and diseases as well as their possible use in diagnosis - Report breakthroughs in the use of small ncRNAs for diagnosis and personalized therapy |
| ncrna types: Epitranscriptomics Stefan Jurga, Jan Barciszewski, 2021-07-28 This book reviews a novel and exciting field of cellular and molecular biology called epitranscriptomics, which focuses on changes in an organism’s cells resulting from the posttranscriptional modification of cellular RNA. RNA-binding proteins (RBPs) play a crucial role in these posttranscriptional modifications and also support several cellular processes necessary for maintaining RNA homeostasis. Exploring the mechanisms underlying RNA modifications and RBP function is an emerging area of biomedical research, taking the study of gene regulation a step beyond epigenetics. This book reveals that the RNA molecule is not just an information-carrying molecule with some secondary structures. Accordingly, how RNA is modified, regulated, packaged, and controlled is an important aspect. Leading experts address questions such as where the over 170 distinct posttranscriptional RNA modifications are located on the genome, what percentage of mRNAs and noncoding RNAs these modifications include, and how an RNA modification impacts a person’s biology. In closing, the book reviews the role of RNA modifications and RBPs in a variety of diseases and their pathogenesis. Addressing some of the most exciting challenges in epitranscriptomics, this book provides a valuable and engaging resource for researchers in academia and industry studying the phenomena of RNA modification. |
| ncrna types: Essential Guide to Neurodegenerative Disorders Wael Mohamed, 2024-11-24 Handbook of Neurodegenerative Disorders: Mechanism, Diagnostic and Therapeutic Advances provides a comprehensive review on the current biomedical studies aimed at identifying the underlying causes of neurodegeneration. This book reviews the most recent developments in molecular and cellular processes altered during neurodegeneration. Divided into four parts, the first covers the mechanism of cell death in neurodegeneration. The second section reviews the recent progress in gene and gene products in neurodegeneration, including Huntington's disease, Parkinson's disease, Friedreich' s ataxia, and spinal muscular atrophy. The final sections cover the current and future diagnostic techniques of neurodegenerative disorders along with therapeutic approaches. - Reviews big data and neurodegeneration disorders, including gene mapping - Examines the structural basis of protein assembly into amyloid filaments in neurodegenerative disease - Covers the progress and challenges of pharmacotherapy of neurodegenerative disorders |
| ncrna types: Non-coding RNA and the Reproductive System Dagmar Wilhelm, Pascal Bernard, 2015-12-11 This book provides an overview of the role and function of regulatory RNAs that lack protein-coding potential in key reproductive tissues. This includes the role of small interfering RNAs (siRNAs), microRNAs (miRNAs), PIWI-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs) and long non-coding RNAs (lncRNAs). Through clear, detailed and comprehensive debate, international leading experts discuss the role these novel regulators in normal development of sexual dimorphisms, including the differentiation of ovaries and testes, the genital tract including prostate, epididymis and uterus, as well as mammary glands. In addition, particular attention is paid on their role in pathophysiological processes within the reproductive tract. The power of next generation sequencing has proved to be an invaluable tool to discover new non-coding RNAs. While the identification of non-coding RNA is relatively easy, analysing their function represents still a challenge today. In this book, authors present historical and conceptual background information, highlight the ways in which non-coding RNAs function is analysed and present their vision of the future research in their key research area. |
| ncrna types: Artificial Intelligence Applications and Innovations Lazaros Iliadis, Ilias Maglogiannis, Vassilis Plagianakos, 2018-05-21 This book constitutes the refereed proceedings of 4 workshops held at the 14th IFIP WG 12.5 International Conference on Artificial Intelligence Applications and Innovations, AIAI 2018, held in Rhodes, Greece, in May 2018. The workshops were the Workshop on Semantics in the Deep: Semantic Analytics for Big Data, SEDSEAL 2018; the Third Workshop on 5G - Putting Intelligence to the Network Edge, 5G-PINE 2018; the 7th Mining Humanistic Data Workshop, MHDW 2018; and the Workshop on Intelligent Cloud and IOT Paradigms in EHealth, HEALTHIOT 2018. The 19 full papers and 5 short papers presented were carefully reviewed and selected from a total of 53 submissions: SEDSEAL accepted 2 full papers out of 5 submissions, 5G-PINE 6 full and one short paper out of 24, MHDW 7 full and 4 short papers out of 15, and HEALTHIOT 4 full papers out of 9. The papers cover topics such as AI in 5G and telecommunications, AI and e-health services, AI in 5G networks, incremental learning, clustering, AI in text mining, visual data analytics, AI in molecular biology, DNA, RNA, proteins, big data analytics, Internet of Things and recommender systems, and AI in biomedical applications. |
| ncrna types: The Role of ncRNA in Cardiac Remodeling Zhanpeng Huang, Kun Wang, Jiandong Liu, 2022-04-20 |
| ncrna types: Pattern Recognition in Computational Molecular Biology Mourad Elloumi, Costas Iliopoulos, Jason T. L. Wang, Albert Y. Zomaya, 2015-11-30 A comprehensive overview of high-performance pattern recognition techniques and approaches to Computational Molecular Biology This book surveys the developments of techniques and approaches on pattern recognition related to Computational Molecular Biology. Providing a broad coverage of the field, the authors cover fundamental and technical information on these techniques and approaches, as well as discussing their related problems. The text consists of twenty nine chapters, organized into seven parts: Pattern Recognition in Sequences, Pattern Recognition in Secondary Structures, Pattern Recognition in Tertiary Structures, Pattern Recognition in Quaternary Structures, Pattern Recognition in Microarrays, Pattern Recognition in Phylogenetic Trees, and Pattern Recognition in Biological Networks. Surveys the development of techniques and approaches on pattern recognition in biomolecular data Discusses pattern recognition in primary, secondary, tertiary and quaternary structures, as well as microarrays, phylogenetic trees and biological networks Includes case studies and examples to further illustrate the concepts discussed in the book Pattern Recognition in Computational Molecular Biology: Techniques and Approaches is a reference for practitioners and professional researches in Computer Science, Life Science, and Mathematics. This book also serves as a supplementary reading for graduate students and young researches interested in Computational Molecular Biology. |
| ncrna types: Genome and Epigenome Editing for Stress-Tolerant Crops Jen-Tsung Chen, 2025-05-06 Provides a timely overview of the use of CRISPR and non-coding RNA technologies to develop climate-resilient crops With mounting challenges from climate change, expanding populations, and resource limitations, the need for resilient and sustainable agricultural systems has never been greater. Genome and Epigenome Editing for Stress-Tolerant Crops summarizes advanced techniques for creating crops that can withstand both biotic and abiotic stressors. Edited by renowned biologist Jen-Tsung Chen, this authoritative volume discusses the coordination of CRISPR/Cas technology with ncRNA-based epigenetics to enhance stress tolerance and improve crop quality. In addition to offering insights into genetic and molecular advances, contributions by experts in the field present key methodologies and applications that bridge multiple omics technologies with genome editing for impactful agricultural outcomes. Addressing emerging tools and strategies that could be instrumental in achieving the United Nations Sustainable Development Goals (SDGs) and advancing sustainable agriculture, Genome and Epigenome Editing for Stress-Tolerant Crops: Provides an in-depth overview of CRISPR/Cas and non-coding RNA strategies to develop stress-tolerant crops. Integrates multiple omics approaches, including genomics, transcriptomics, and metabolomics for comprehensive crop improvement. Discusses strategies for resilience against both abiotic and biotic stressors, such as drought, salinity, pests, and pathogens. Offers practical applications of CRISPR and RNA technologies for high-yield, high-quality crop development. Presents recent research advancements in epigenetic regulation to fine-tune plant stress responses. Discusses future directions in plant science to inspire new research and experimental designs. Genome and Epigenome Editing for Stress-Tolerant Crops is essential reading for advanced undergraduate and graduate courses in plant biology, molecular genetics, and agricultural biotechnology. It is also a valuable reference for researchers, plant breeders, and scientists working on crop improvement and climate-resilient agriculture initiatives. |
| ncrna types: Combating cancer with natural products: Non-coding RNA and RNA modification Yongye Huang, Yun Dai, Peng Qu, Yue Hou, 2023-03-15 |
| ncrna types: Thompson & Thompson Genetics in Medicine Robert L. Nussbaum, Roderick R. McInnes, Huntington F Willard, 2015-05-21 Updated to reflect the newest changes in genetics, Thompson & Thompson's Genetics in Medicine returns as one of the most favored texts in this fascinating and rapidly evolving field. By integrating the classic principles of human genetics with modern molecular genetics, this medical reference book utilizes a variety of learning tools to help you understand a wide range of genetic disorders. Acquire the state-of-the-art knowledge you need on the latest advances in molecular diagnostics, the Human Genome Project, pharmacogenetics, and bio-informatics. Better understand the relationship between basic genetics and clinical medicine with a variety of clinical case studies. Recognize a wide range of genetic disorders with visual guidance from more than 240 dynamic illustrations and high-quality photos. Immerse yourself in updated graphics, full-color text, illustrations, line diagrams, and clinical photos of genetic diseases. Explore the latest genetic content available in order to remain up to date on the most current trends in the field. Take advantage of a double-page clinical case study section that demonstrates and reinforces general principles of disease inheritance, pathogenesis, diagnosis, management, and counseling. Enhance your critical thinking skills and better retain information. Each chapter ends with up to 5 quick genetic problems related to what has just been reviewed, with answers provided in the back of the book. Student Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices. You'll also access USMLE-style and multiple choice questions. |
| ncrna types: Computational Biomedicine Peter Coveney, Vanessa Díaz-Zuccarini, Peter Hunter, Marco Viceconti, 2014-06 Computational Biomedicine unifies the different strands of a broad-ranging subject to demonstrate the power of a tool that has the potential to revolutionise our understanding of the human body, and the therapeutic strategies available to maintain and protect it. |
| ncrna types: Thompson & Thompson Genetics and Genomics in Medicine E-Book Ronald Cohn, Stephen Scherer, Ada Hamosh, 2023-07-10 First published in 1966, Thompson and Thompson Genetics and Genomics in Medicine has become an essential textbook for medical students, genetic counseling students, students in laboratory medicine, and more advanced trainees. With its focus on fundamental principles in human genetics and genomics and their application to medicine, the book has served many as a well-thumbed resource they return to over and over. Such students can continue to depend on this valuable text, joining those in newer fields of genome data analysis for all they need to know about genetics and genomics throughout their basic science training, clinical placements and beyond. Coverage includes new discoveries—such as the functional roles of non-coding RNAs, chromatin regulation and epigenetics—latest technologies, and new diagnoses they are enabling. Under an expanded title, this ninth edition has been completely revised by a new editorial team overseeing a large cadre of contributing authors. Support groups have also assisted to update illustrations featuring beautiful images of those living with genetic conditions. - Comprehensive coverage of: genomes in biology and medicine; copy number and structural genomic variation; novel discoveries; latest technology; and new genetic diagnoses - Over 40 clinical case studies, capturing the latest challenges of variable expression, pleiotropy, and complex disorders through new diagnostic strategies - Full-color text, illustrations, updated line diagrams, and clinical photos - End-of-chapter questions and comprehensive answers to challenge the reader to consolidate the material into practice and prepare for examination - An enhanced eBook version is included with purchase. The eBook allows you to access all the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud - Updated and new clinical cases, supported with photography by the not-for-profit organization, Positive Exposure - New content on growing role of sequencing and novel functional assays in diagnosis and screening of genetic conditions - New chapter on Epigenetics - Clearer and more precise terminology, in response to contemporary and evolving guidelines - New sections describing the use (and need for) genetic information from diverse populations, including unique indigenous and founder populations, for diagnosis and management. |
| ncrna types: The Role of ncRNAs in Solid Tumors Prognosis: From Laboratory To Clinical Utility Jian-Guo Zhou, Zhaohui Huang, Ondrej Slaby, Alfons Navarro, 2021-03-23 |
| ncrna types: Computational Systems Bioinformatics (Volume 7) - Proceedings Of The Csb 2008 Conference Peter Markstein, Ying Xu, 2008-08-01 This proceedings volume contains 29 papers covering many of the latest developments in the fast-growing field of bioinformatics. The contributions span a wide range of topics, including computational genomics and genetics, protein function and computational proteomics, the transcriptome, structural bioinformatics, microarray data analysis, motif identification, biological pathways and systems, and biomedical applications.The papers not only cover theoretical aspects of bioinformatics but also delve into the application of new methods, with input from computation, engineering and biology disciplines. This multidisciplinary approach to bioinformatics gives these proceedings a unique viewpoint of the field./a |
| ncrna types: The Elusive Road Towards Effective Cancer Prevention and Treatment Franklyn De Silva, Jane Alcorn, 2022-10-28 Cancer will remain a global major health problem unless new diagnostic, prognostic, and management approaches are discovered to address both loss of life and quality of life. Here we summarize the general physiology, pathology, heterogeneity, and evolution of cancer, current status, limitations and challenges associated with prevention, incidence, treatment, survival, and mortality, as well as future directions with regards to solid tumors. Perspectives are provided on how to improve pre-clinical understandings, outcomes, and patient care. Further, this comprehensive, timely overview of the literature has educational value as part of an academic course, seminar, or as a supplementary text. Features : This book summarizes the current status, successes, difficulties, advancements, limitations, and challenges in medical interventions that impact patients’ quality of life. Includes concise descriptions of all relevant cell and molecular biology concepts including evolutionary paradigms, hallmarks of cancer, and heterogeneity to help understand the pathophysiology of cancer, cancer-associated disease conditions, and effective cancer therapy. Contains an array of colorful figures and schematics summarizing complex informative pathological, physiological, and biochemical concepts. Covers a multitude of sub-topics pertaining to cancer biology including diagnosis; chemotherapy, radiotherapy and targeted therapy; metastasis; disseminated and circulating tumor cells, and cancer stem cells; drug resistance and cellular reprogramming; complex epigenetics; tumor-derived exosomes; oncogenic viruses; metabolic syndrome and cancer metabolism; convoluted neovascularization; efficient biomarkers; immunotherapy; role of nutraceuticals and natural products. Provides perspectives on how to improve pre-clinical understandings, and outcomes, linking toxicological, and pharmacological aspects in patient care. This timely, relevant comprehensive assortment of scientific literature has educational value to a wider audience including as part of an academic course, seminar, or as a supplementary text. |
| ncrna types: Clinical Applications of Noncoding RNAs in Cancer Subash Gupta, Kishore Challagundla, 2022-01-19 Clinical Applications of Noncoding RNAs in Cancer summarizes the existing strategies, advances, and future opportunities on the role of noncoding RNAs in cancer patients. Established clinicians and researchers from all around the world share their views and expertise and provide readers with invaluable knowledge on the subject. This book provides a comprehensive collection of information on the utility of noncoding RNAs in the diagnosis, prognosis, and therapy of cancer. It also discusses the evolutionary significance of noncoding RNAs and how the molecular tools such as RNA-seq, RNA-FISH, ic-SHAPE, and quantitative real-time PCR help in the detection and elucidation of the functions of noncoding RNAs. Additionally, the challenges associated with noncoding RNA approaches and future developments are discussed. It is a valuable resource for cancer researchers, oncologists, clinicians, and other biomedical field members who want to learn more about noninvasive ways to diagnose and efficiently treat diverse cancer types. - Presents a beginning chapter summary to help readers understand the content thoroughly - Encompasses detailed description of information from clinical studies on noncoding RNAs in cancer therapy - Discusses one cancer type per chapter making the content easy to reference |
| ncrna types: Computational Systems Bioinformatics Peter Markstein, 2008 This proceedings volume contains 29 papers covering many of the latest developments in the fast-growing field of bioinformatics. The contributions span a wide range of topics, including computational genomics and genetics, protein function and computational proteomics, the transcriptome, structural bioinformatics, microarray data analysis, motif identification, biological pathways and systems, and biomedical applications.The papers not only cover theoretical aspects of bioinformatics but also delve into the application of new methods, with input from computation, engineering and biology disciplines. This multidisciplinary approach to bioinformatics gives these proceedings a unique viewpoint of the field. |
| ncrna types: Cancer Metastasis Through the Lymphovascular System Stanley P. Leong, S. David Nathanson, Jonathan S. Zager, 2022-06-24 This textbook describes in detail the process of cancer metastasis from a single cell in the primary site through its arduous journey to the sentinel lymph node as the main gateway and beyond to distant sites. The most up-to-date knowledge on key topics in the molecular biology, diagnosis, and treatment of metastatic cancer is highlighted by a large panel of experts. The book begins with a comprehensive overview of the genetic and molecular mechanisms that promote or inhibit cancer metastasis through lymphatic pathways to lymph nodes or through vascular pathways to distant sites, providing the reader with an essential basic knowledge. This is followed by further details on the role of the immune system within the primary tumor and the lymph node and the importance of the microenvironment at the metastatic site. The role of the sentinel lymph node in cancer metastasis is emphasized. Special attention is also given to state-of-the-art imaging techniques for the detection of early-stage cancer and cancer metastases, as well as the use of liquid biopsies in sarcoma, prostate, gastrointestinal, and lung cancer. Clinical patterns of malignant tumors arising in different organ systems are compared, described, and discussed with the goal of determining what similarities and/or differences exist. The book concludes with a detailed discussion of surgical intervention, radiation, and systemic therapy of primary and metastatic cancer, and briefly previews several emerging topics, such as the latest findings on personalized cancer therapy, cancer stem cells, unique molecular mechanisms of virus-induced cancer, the impact of the microbiome on cancer metastasis and the application of artificial intelligence in cancer metastasis research. By providing fundamental knowledge of the biological and clinical aspects of cancer metastasis, this book will be an important reference for cancer researchers, clinical oncologists, teachers, and students. Written by experts in the field, each chapter includes a summary of the chapter's key points and open-ended questions that address pressing issues in the field and encourage the reader to consider future directions. |
| ncrna types: Cellular Oxidative Stress Silvia Dossena, Angela Marino , 2021-09-06 This book collects 17 original research papers and 9 reviews that are part of the Special Issue “Cellular Oxidative Stress”, published in the journal Antioxidants. Oxidative stress on a cellular level affects the function of tissues and organs and may eventually lead to disease. Therefore, a precise understanding of how oxidative stress develops and can be counteracted is of utmost importance. The scope of the book is to emphasize the latest findings on the cellular targets of oxidative stress and the potential beneficial effect of antioxidants on human health. |
| ncrna types: Fundamentals of Advanced Omics Technologies: From Genes to Metabolites , 2014-02-14 Fundamentals of Advanced Omics Technologies: From Genes to Metabolites covers the fundamental aspects of the new instrumental and methodological developments in omics technologies, including those related to genomics, transcriptomics, epigenetics, proteomics and metabolomics, as well as other omics approaches such as glycomics, peptidomics and foodomics. The principal applications are presented in the following complementary volume. The chapters discuss in detail omics technologies, DNA microarray analysis, next-generation sequencing technologies, genome-wide analysis of methylation and histone modifications, emerging nanotechniques in proteomics, imaging mass spectrometry in proteomics, recent quantitative proteomics approaches, and advances in high-resolution NMR-based metabolomics, as well as MS-based non-targeted metabolomics and metabolome analysis by CE-MS, global glycomics analyses, foodomics, and high resolution analytical tools for quantitative peptidomics. Key aspects related to chemometrics, bioinformatics, data treatment, data integration and systems biology, deep-sequencing data analysis, statistical approaches for the analysis of microarray data, the integration of transcriptome and metabolome data and computational approaches for visualization and integration of omics data are also covered. - Covers the latest advances in instrumentation, experimental design, sample preparation, and data analysis - Provides thorough explanations and descriptions of specific omics technologies - Describes advanced tools and methodologies for data pretreatment, storage, curation and analysis, as well as data integration |
| ncrna types: Comprehensive Foodomics , 2020-11-12 Comprehensive Foodomics, Three Volume Set offers a definitive collection of over 150 articles that provide researchers with innovative answers to crucial questions relating to food quality, safety and its vital and complex links to our health. Topics covered include transcriptomics, proteomics, metabolomics, genomics, green foodomics, epigenetics and noncoding RNA, food safety, food bioactivity and health, food quality and traceability, data treatment and systems biology. Logically structured into 10 focused sections, each article is authored by world leading scientists who cover the whole breadth of Omics and related technologies, including the latest advances and applications. By bringing all this information together in an easily navigable reference, food scientists and nutritionists in both academia and industry will find it the perfect, modern day compendium for frequent reference. List of sections and Section Editors: Genomics - Olivia McAuliffe, Dept of Food Biosciences, Moorepark, Fermoy, Co. Cork, Ireland Epigenetics & Noncoding RNA - Juan Cui, Department of Computer Science & Engineering, University of Nebraska-Lincoln, Lincoln, NE Transcriptomics - Robert Henry, Queensland Alliance for Agriculture and Food Innovation, The University of Queensland, St Lucia, Australia Proteomics - Jens Brockmeyer, Institute of Biochemistry and Technical Biochemistry, University Stuttgart, Germany Metabolomics - Philippe Schmitt-Kopplin, Research Unit Analytical BioGeoChemistry, Neuherberg, Germany Omics data treatment, System Biology and Foodomics - Carlos Leon Canseco, Visiting Professor, Biomedical Engineering, Universidad Carlos III de Madrid Green Foodomics - Elena Ibanez, Foodomics Lab, CIAL, CSIC, Madrid, Spain Food safety and Foodomics - Djuro Josic, Professor Medicine (Research) Warren Alpert Medical School, Brown University, Providence, RI, USA & Sandra Kraljevic Pavelic, University of Rijeka, Department of Biotechnology, Rijeka, Croatia Food Quality, Traceability and Foodomics - Daniel Cozzolino, Centre for Nutrition and Food Sciences, The University of Queensland, Queensland, Australia Food Bioactivity, Health and Foodomics - Miguel Herrero, Department of Bioactivity and Food Analysis, Foodomics Lab, CIAL, CSIC, Madrid, Spain Brings all relevant foodomics information together in one place, offering readers a ‘one-stop,’ comprehensive resource for access to a wealth of information Includes articles written by academics and practitioners from various fields and regions Provides an ideal resource for students, researchers and professionals who need to find relevant information quickly and easily Includes content from high quality authors from across the globe |
| ncrna types: Long Non Coding RNA Biology M.R.S. Rao, 2017-08-16 This contributed volume offers a comprehensive and detailed overview of the various aspects of long non-coding RNAs and discusses their emerging significance. Written by leading experts in the field, it motivates young researchers around the globe, and offers graduate and postgraduate students fascinating insights into genes and their regulation in eukaryotes and higher organisms. |
| ncrna types: Frontiers In Autism Research: New Horizons For Diagnosis And Treatment Valerie W Hu, 2014-05-09 This book focuses on the emerging and expanding areas of research on ASD and their potential to lead to better diagnosis and more effective therapies. These areas include innovative and integrative approaches to genetic/genomic analyses and investigations of epigenetic contributions, including the role of noncoding RNAs, DNA methylation, alternative splicing, RNA editing, and faulty translation in gene regulation and expression, metabolic and immune dysfunction, co-morbidities, as well as hormonal and gene-environment interactions that may increase risk for ASD.Within each chapter, experts review cutting-edge research as well as provide their perspective on the future of research in their respective areas, including the challenges involved and the types of studies or advances that are necessary to move the field forward to achieve predicted translational goals.Contributors: Argel Aguilar-Valles, Evdokia Anagnostou, Emma Ashwin, Bonnie Auyeung, Kelly M Bakulski, Simon Baron-Cohen, Margaret L Bauman, Donna Betts, Chad A Bousman, Daniel B Campbell, Manuel F Casanova, Bhismadev Chakrabarti, Gursharan Chana, Abha Chauhan, Ved Chauhan, Jessica DeWitt, Keith W Dunaway, Alal Eran, Ian P Everall, M Daniele Fallin, Richard E Frye, Piers Gillett, Matthew Ginsberg, Christos G Gkogkas, Rhonda J Greenhaw, Simon G Gregory, Elena L Grigorenko, Feng Gu, Rebecca Harmer, Martha Herbert, Valerie W Hu, Karen L Jones, Petra Kern, Arkady Khoutorsky, Rebecca Knickmeyer, Isaac S Kohane, Louis M Kunkel, Janine M LaSalle, Michael V Lombardo, Deepali Mankad, Marvin Natowicz, Laura Nicholls, Christos Pantelis, Natalia Rakhlin, Radhika Ramadas, Daniel A Rossignol, Tewarit Sarachana, Stephen W Scherer, Gabriela Schmulevich, Ayten Shah, Frank R Sharp, Alison B Singer, Efstratios Skafidas, Estate M Sokhadze, Nahum Sonenberg, Boryana Stamova, Zohreh Talebizadeh, Renee Testa, Judy Van de Water, Irina Voineagu, Daniel Williams, Ryan K C Yuen, Daniela Zantomio. |
| ncrna types: MicroRNAs in Cancer Cesar Lopez-Camarillo, Laurence A. Marchat, 2013-02-22 MicroRNA (miRNA) biology is a cutting-edge topic in basic as well as biomedical research. This is a specialized book focusing on the current understanding of the role of miRNAs in the development, progression, invasion, and metastasis of diverse types of cancer. It also reviews their potential for applications in cancer diagnosis, prognosis, and th |
| ncrna types: Genetic Engineering and Molecular Techniques Mr. Rohit Manglik, 2024-04-17 EduGorilla Publication is a trusted name in the education sector, committed to empowering learners with high-quality study materials and resources. Specializing in competitive exams and academic support, EduGorilla provides comprehensive and well-structured content tailored to meet the needs of students across various streams and levels. |
| ncrna types: Recent Developments in Myelodysplastic Syndromes Ota Fuchs, 2019-02-20 This book deals with the rapid progress in the area of myelodysplastic syndromes (MDS). MDS are a group of age-associated heterogeneous malignant bone marrow stem cell disorders. MDS are characterized by ineffective hematopoiesis, which leads to refractory cytopenias and to clonal instability. Patients with MDS have myeloid dysplasia, intramedullary apoptosis and an increased risk of transformation to acute myeloid leukemia (AML). The use of next generation sequencing has allowed for the identification of molecular mutations in several genes in about 90% of MDS patients. Several mutations will likely be incorporated into future prognostic scoring systems for MDS. About 50% of MDS cases are characterized by the presence of cytogenetic abnormalities. The correct morphological and cytogenetic analysis interpretation plays an important role in diagnosis and prognosis of these disorders. Cell death and an inflammatory gene signature are associated with MDS. Better understanding of the genetic and molecular mechanisms of MDS pathogenesis provides an opportunity for new treatment strategies to be developed. Promising novel therapies targeting pathophysiological mechanisms of MDS are being studied but the drugs currently used in MDS therapy remain limited. The only curative therapy for MDS is allogeneic hematopoietic stem cell transplantation. Recent advances in strategies to minimize transplant-related toxicity make this treatment possible for more MDS patients who are sufficiently fit. |
| ncrna types: Animal Models of Speech and Language Disorders Santosh A. Helekar, 2013-10-17 Basic research over the last decade or two has uncovered similarities between speech, especially its sensori-motor aspects, and vocal communication in several non-human species. The most comprehensive studies so far have been conducted in songbirds. Songbirds offer us a model system to study the interactions between developmental or genetic predispositions and tutor-dependent influences, on the learning of vocal communication. Songbird research has elucidated cellular and molecular mechanisms underlying learning and production of vocal patterns, perception of vocal sounds, vocal motor control and vocal neuromotor plasticity. More recently, the entire genome of the songbird zebra finch has been sequenced. These discoveries, along with the identification of several genes implicated in familial human speech and language disorders, have made it possible to look for analogues of speech and language dysfunction in zebra finches, at least at the perceptual and sensori-motor levels. Two approaches in particular have led us closer to the development of animal models of human speech conditions, namely developmental stuttering and a familial verbal dyspraxia associated with a mutation in the gene for the transcription factor FoxP2. Work on other animals that show developmental sensori-motor learning of vocal sounds used for communication have also shown significant progress, leading to the possibility of development of models of speech and language dysfunction in them. Among mammals, the principal ones include dolphins and whales. In non-human primates, while vocal learning per se is not very prominent, investigations on their communicative abilities have thrown some light on the rudiments of language. These considerations make the publication of a book focused on animal models of speech and language disorders, detailing the overall investigative approach of neurobehavioral studies in animals capable of vocal communication and learned vocalizations, a much-needed and worthwhile project. It would serve as a unifying review of research in this new multidisciplinary frontier, spanning the molecular to the behavioral, for clinicians and researchers, as well as a teaching resource for advanced speech pathology and neuroscience students. This book will also be the first of its kind. |
| ncrna types: MicroRNA Cancer Regulation Ulf Schmitz, Olaf Wolkenhauer, Julio Vera, 2013-02-03 This edited reflects the current state of knowledge about the role of microRNAs in the formation and progression of solid tumours. The main focus lies on computational methods and applications, together with cutting edge experimental techniques that are used to approach all aspects of microRNA regulation in cancer. We are sure that the emergence of high-throughput quantitative techniques will make this integrative approach absolutely necessary in the near future. This book will be a resource for researchers starting out with cancer microRNA research, but is also intended for the experienced researcher who wants to incorporate concepts and tools from systems biology and bioinformatics into his work. Bioinformaticians and modellers are provided with a general perspective on microRNA biology in cancer, and the state-of-the-art in computational microRNA biology. |
| ncrna types: Molecular Pharmacology John Dickenson, Fiona Freeman, Chris Lloyd Mills, Christian Thode, Shiva Sivasubramaniam, 2012-11-30 This textbook provides a fresh, comprehensive and accessible introduction to the rapidly expanding field of molecular pharmacology. Adopting a drug target-based, rather than the traditional organ/system based, approach this innovative guide reflects the current advances and research trend towards molecular based drug design, derived from a detailed understanding of chemical responses in the body. Drugs are then tailored to fit a treatment profile, rather than the traditional method of ‘trial and error’ drug discovery which focuses on testing chemicals on animals or cell cultures and matching their effects to treatments. Providing an invaluable resource for advanced under-graduate and MSc/PhD students, new researchers to the field and practitioners for continuing professional development, Molecular Pharmacology explores; recent advances and developments in the four major human drug target families (G-protein coupled receptors, ion channels, nuclear receptors and transporters), cloning of drug targets, transgenic animal technology, gene therapy, pharmacogenomics and looks at the role of calcium in the cell. Current - focuses on cutting edge techniques and approaches, including new methods to quantify biological activities in different systems and ways to interpret and understand pharmacological data. Cutting Edge - highlights advances in pharmacogenomics and explores how an individual’s genetic makeup influences their response to therapeutic drugs and the potential for harmful side effects. Applied - includes numerous, real-world examples and a detailed case-study based chapter which looks at current and possible future treatment strategies for cystic fibrosis. This case study considers the relative merits of both drug therapy for specific classes of mutation and gene therapy to correct the underlying defect. Accessible - contains a comprehensive glossary, suggestions for further reading at the end of each chapter and an associated website that provides a complete set of figures from within the book. |
Non-coding RNA - Wikipedia
A non-coding RNA (ncRNA) is a functional RNA molecule that is not translated into a protein. The DNA sequence from which a functional non-coding RNA is transcribed is often called an RNA …
Non-coding RNAs: Classification, Biology and Functioning
More recently, several classes of short regulatory non-coding RNAs, including piwi-associated RNAs, endogenous short-interfering RNAs and microRNAs have been discovered in …
Emerging role of non‐coding RNA in health and disease - PMC
Non-coding RNAs (ncRNAs) have now emerged as indispensable players in the diagnosis, development, and therapeutics of every abnormality concerning physiology, pathology, …
Non–coding RNA genes and the modern RNA world - Nature
Dec 1, 2001 · Non-coding RNA (ncRNA) genes produce functional RNA molecules rather than encoding proteins. However, almost all means of gene identification assume that genes …
Long non-coding RNAs: definitions, functions, challenges and ...
Jan 3, 2023 · Genes specifying long non-coding RNAs (lncRNAs) occupy a large fraction of the genomes of complex organisms. The term ‘lncRNAs’ encompasses RNA polymerase I (Pol I), …
Non-coding RNA: Types and their role in diseases | Abcam
Non-coding RNAs (ncRNA) are transcribed from DNA but do not translate into proteins. They play crucial roles in regulating gene expression at both the transcriptional and post-transcriptional …
Coding and Non-Coding RNA - Bio-Rad
Learn about the diverse classes of noncoding RNAs, the structures and origins of different ncRNA species, their biological functions, and clinical implications.
Non-coding RNA - Wikipedia
A non-coding RNA (ncRNA) is a functional RNA molecule that is not translated into a protein. The DNA sequence from which a functional non-coding RNA is transcribed is often called an RNA …
Non-coding RNAs: Classification, Biology and Functioning
More recently, several classes of short regulatory non-coding RNAs, including piwi-associated RNAs, endogenous short-interfering RNAs and microRNAs have been discovered in …
Emerging role of non‐coding RNA in health and disease - PMC
Non-coding RNAs (ncRNAs) have now emerged as indispensable players in the diagnosis, development, and therapeutics of every abnormality concerning physiology, pathology, …
Non–coding RNA genes and the modern RNA world - Nature
Dec 1, 2001 · Non-coding RNA (ncRNA) genes produce functional RNA molecules rather than encoding proteins. However, almost all means of gene identification assume that genes …
Long non-coding RNAs: definitions, functions, challenges and ...
Jan 3, 2023 · Genes specifying long non-coding RNAs (lncRNAs) occupy a large fraction of the genomes of complex organisms. The term ‘lncRNAs’ encompasses RNA polymerase I (Pol I), …
Non-coding RNA: Types and their role in diseases | Abcam
Non-coding RNAs (ncRNA) are transcribed from DNA but do not translate into proteins. They play crucial roles in regulating gene expression at both the transcriptional and post-transcriptional …
Coding and Non-Coding RNA - Bio-Rad
Learn about the diverse classes of noncoding RNAs, the structures and origins of different ncRNA species, their biological functions, and clinical implications.
