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ngs ppt: Extracellular Vesicles Wojciech Chrzanowski, Chwee Teck Lim, Sally Yunsun Kim, 2021-10-20 Extracellular and biofluids vesicles (EVs) are highly specialised yet ubiquitous nanoscale messengers secreted by cells. With the development of stem cell engineering, EVs promise to deliver next generation tools in regenerative medicine and tissue engineering, as well as in diagnostics. A vibrant and promising field, this book provides the first resource to the field. Covering basic cell biology, including EV production and intracellular communication, this book will provide material scientists and engineers with a foundation to the necessary biology. The reader will then learn about the isolation of extracellular vesicles their physicochemical characterisation and therapeutic application of EVs in regenerative medicine as well as their potential as biomarkers in medical diagnostic. This book will also discuss the regulatory landscape of EVs. Bridging cell biology, biomaterials, biophysics and biomedical engineering the content of this book is written with a broad interdisciplinary audience in mind. Researchers, new and established will find this a must-have on their shelf. |
ngs ppt: NASA Thesaurus , 1994 |
ngs ppt: An Introduction to the Geography of Tourism Velvet Nelson, 2017-03-03 Tourism is an astonishingly complex phenomenon that is becoming an ever-greater part of life in today’s global world. This clear and engaging text introduces undergraduate students to this vast subject through the lens of geography, the only field with the breadth to consider all of the aspects, activities, and perspectives that constitute tourism. |
ngs ppt: Crop Improvement in the Era of Next-Generation Sequencing Manohar Chakrabarti, Umesh K. Reddy , Nabanita Chattopadhyay, 2025-02-27 To feed the burgeoning world population, global food production must increase drastically. This is becoming more challenging with the imminent threats of global climate change, especially the incidences of abiotic stresses, such as drought, heat, and salinity are predicted to increase soon. Global climate change may also affect plant-biotic interactions. Additionally, modernization in underdeveloped and developing countries is expected to decrease available land for agricultural usage. Thus, to achieve sustainable agricultural development, it is imperative to produce more food without using additional land and other valuable resources, including water. These necessitates should develop novel, rapid, and robust crop improvement methods that complement traditional plant breeding approaches. Crop improvement strategies to tackle future challenges necessitate the elucidation of underlying genes and gene regulatory networks. The dwindling cost of next-generation sequencing and the emergence of novel sequencing approaches, such as long-read sequencing technology (e.g., PacBio, Oxford Nanopore, and others) are transforming agricultural research at an unprecedented rate is opening a plethora of opportunities in turbocharging crop improvement initiatives. Recent advances in next-generation sequencing will continue to play a pivotal role in future crop improvement efforts. However, the progress of genomic technologies has not been uniformed world-wide. Thus, it is now relevant to compile a collection of recent advancements in the field of structural, functional, and comparative genomics and its relevance to crop improvement, so that it is disseminated to a broader audience. |
ngs ppt: Research & Development , 1995-07 |
ngs ppt: Applied Computer Science for GGOS Observatories Alexander N.J. Neidhardt, 2017-08-08 This book combines elementary theory from computer science with real-world challenges in global geodetic observation, based on examples from the Geodetic Observatory Wettzell, Germany. It starts with a step-by-step introduction to developing stable and safe scientific software to run successful software projects. The use of software toolboxes is another essential aspect that leads to the application of generative programming. An example is a generative network middleware that simplifies communication. One of the book’s main focuses is on explaining a potential strategy involving autonomous production cells for space geodetic techniques. The complete software design of a satellite laser ranging system is taken as an example. Such automated systems are then combined for global interaction using secure communication tunnels for remote access. The network of radio telescopes is used as a reference. Combined observatories form coordinated multi-agent systems and offer solutions for operational aspects of the Global Geodetic Observing System (GGOS) with regard to “Industry 4.0”. |
ngs ppt: Physical and Chemical Examination of Paints, Varnishes, and Colors Henry Alfred Gardner, 1940 |
ngs ppt: Organic Chemistry of the Earth’s Atmosphere Valerii A. Isidorov, 1990-05-21 Organic chemicals constitute minor gaseous components of the earth's atmosphere. Despite low concentrations they play an important role in the global processes influencing the composition of our atmosphere. The author summarizes the multidisciplinary data on sources and thermo- and photochemical transformations of organic components in the atmosphere. Modern methods of atmospheric microimpurity analysis are explained. Models for their time-dimensional distribution both in the urban atmosphere and in unpolluted air are developed. The book provides a unique source of contemporary information for scientists involved in atmospheric chemistry, meteorology, ecology and geophysics. |
ngs ppt: Plant Transposable Elements Marie-Angèle Grandbastien, Josep Casacuberta, 2013-01-08 Transposable elements are short lengths of DNA with the capacity to move between different points within a genome. This process can affect the function of genes at or near the insertion site. The present book gives an overview of the impact of transposable elements on plant genomes and explains how to recognize and study transposable elements, e.g. by using state-of-the-art strategies like “new generation sequencing.” Moreover, the impact of transposable elements on plant genome structure and function is reviewed in detail, and also illustrated in examples and case studies. The book is intended both for readers familiar with the field and for newcomers. With large-scale sequencing becoming increasingly available, more and more people will come across transposable element sequences in their data, and this volume will hopefully help to convince them that they are not just “junk DNA.” |
ngs ppt: Immunoassays Robert M. Nakamura, William R. Dito, Ernest S. Tucker, 1980 |
ngs ppt: Clinical Applications for Next-Generation Sequencing Urszula Demkow, Rafal Ploski, 2015-09-10 Clinical Applications for Next Generation Sequencing provides readers with an outstanding postgraduate resource to learn about the translational use of NGS in clinical environments. Rooted in both medical genetics and clinical medicine, the book fills the gap between state-of-the-art technology and evidence-based practice, providing an educational opportunity for users to advance patient care by transferring NGS to the needs of real-world patients. The book builds an interface between genetic laboratory staff and clinical health workers to not only improve communication, but also strengthen cooperation. Users will find valuable tactics they can use to build a systematic framework for understanding the role of NGS testing in both common and rare diseases and conditions, from prenatal care, like chromosomal abnormalities, up to advanced age problems like dementia. - Fills the gap between state-of-the-art technology and evidence-based practice - Provides an educational opportunity which advances patient care through the transfer of NGS to real-world patient assessment - Promotes a practical tool that clinicians can apply directly to patient care - Includes a systematic framework for understanding the role of NGS testing in many common and rare diseases - Presents evidence regarding the important role of NGS in current diagnostic strategies |
ngs ppt: Applications of Random Matrices in Physics Édouard Brezin, Vladimir Kazakov, Didina Serban, Paul Wiegmann, Anton Zabrodin, 2006-07-03 Random matrices are widely and successfully used in physics for almost 60-70 years, beginning with the works of Dyson and Wigner. Although it is an old subject, it is constantly developing into new areas of physics and mathematics. It constitutes now a part of the general culture of a theoretical physicist. Mathematical methods inspired by random matrix theory become more powerful, sophisticated and enjoy rapidly growing applications in physics. Recent examples include the calculation of universal correlations in the mesoscopic system, new applications in disordered and quantum chaotic systems, in combinatorial and growth models, as well as the recent breakthrough, due to the matrix models, in two dimensional gravity and string theory and the non-abelian gauge theories. The book consists of the lectures of the leading specialists and covers rather systematically many of these topics. It can be useful to the specialists in various subjects using random matrices, from PhD students to confirmed scientists. |
ngs ppt: A Pattern Language Christopher Alexander, 2018-09-20 You can use this book to design a house for yourself with your family; you can use it to work with your neighbors to improve your town and neighborhood; you can use it to design an office, or a workshop, or a public building. And you can use it to guide you in the actual process of construction. After a ten-year silence, Christopher Alexander and his colleagues at the Center for Environmental Structure are now publishing a major statement in the form of three books which will, in their words, lay the basis for an entirely new approach to architecture, building and planning, which will we hope replace existing ideas and practices entirely. The three books are The Timeless Way of Building, The Oregon Experiment, and this book, A Pattern Language. At the core of these books is the idea that people should design for themselves their own houses, streets, and communities. This idea may be radical (it implies a radical transformation of the architectural profession) but it comes simply from the observation that most of the wonderful places of the world were not made by architects but by the people. At the core of the books, too, is the point that in designing their environments people always rely on certain languages, which, like the languages we speak, allow them to articulate and communicate an infinite variety of designs within a forma system which gives them coherence. This book provides a language of this kind. It will enable a person to make a design for almost any kind of building, or any part of the built environment. Patterns, the units of this language, are answers to design problems (How high should a window sill be? How many stories should a building have? How much space in a neighborhood should be devoted to grass and trees?). More than 250 of the patterns in this pattern language are given: each consists of a problem statement, a discussion of the problem with an illustration, and a solution. As the authors say in their introduction, many of the patterns are archetypal, so deeply rooted in the nature of things that it seemly likely that they will be a part of human nature, and human action, as much in five hundred years as they are today. |
ngs ppt: Precise Geodetic Infrastructure National Research Council, Division on Earth and Life Studies, Board on Earth Sciences and Resources, Committee on Seismology and Geodynamics, Committee on the National Requirements for Precision Geodetic Infrastructure, 2010-10-25 Geodesy is the science of accurately measuring and understanding three fundamental properties of Earth: its geometric shape, its orientation in space, and its gravity field, as well as the changes of these properties with time. Over the past half century, the United States, in cooperation with international partners, has led the development of geodetic techniques and instrumentation. Geodetic observing systems provide a significant benefit to society in a wide array of military, research, civil, and commercial areas, including sea level change monitoring, autonomous navigation, tighter low flying routes for strategic aircraft, precision agriculture, civil surveying, earthquake monitoring, forest structural mapping and biomass estimation, and improved floodplain mapping. Recognizing the growing reliance of a wide range of scientific and societal endeavors on infrastructure for precise geodesy, and recognizing geodetic infrastructure as a shared national resource, this book provides an independent assessment of the benefits provided by geodetic observations and networks, as well as a plan for the future development and support of the infrastructure needed to meet the demand for increasingly greater precision. Precise Geodetic Infrastructure makes a series of focused recommendations for upgrading and improving specific elements of the infrastructure, for enhancing the role of the United States in international geodetic services, for evaluating the requirements for a geodetic workforce for the coming decades, and for providing national coordination and advocacy for the various agencies and organizations that contribute to the geodetic infrastructure. |
ngs ppt: Savannah Harbor Expansion Project Chatman County, Georgia and Jasper County, South Carolina United States. Office of the Assistant Secretary of the Army (Civil Works), 2013 |
ngs ppt: Diagnostic Molecular Pathology William B. Coleman, Gregory J. Tsongalis, 2023-10-18 Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing, Second Edition assembles a group of experts to discuss the molecular basis and mechanisms of major human diseases and disease processes and how the molecular features of disease can be harnessed to develop practical molecular tests for disease detection, diagnosis and prognosis. The book explains how molecular tests are utilized in the treatment of patients in personalized medicine, highlights new technologies and approaches of applied molecular pathology, and discusses how this discovery-based research yields new and useful biomarkers and tests. As it is essential to stay up-to-date on new molecular diagnostics in this changing field, this book covers critically important areas in the practice of personalized medicine and reflects our understanding of the pathology, pathogenesis and pathophysiology of human disease. - Includes new material on mass spectrometry for infectious diseases, microbiome, homology-directed repair for PARPi, whole genome sequencing for constitutional testing, and much more - Provides insights on the value of the molecular test in comparison to traditional methods, which include speed, precision, sensitivity and clinical impacts for the patient - Focuses on the menu of molecular diagnostic tests available in modern molecular pathology or clinical laboratories that can be applied to disease detection, diagnosis and classification in the clinical workup of a patient - Explains how molecular tests are utilized to guide the treatment of patients in personalized medicine (guided therapies) and for the prognostication of disease |
ngs ppt: DNA Sequencing Anjana Munshi, 2012 This book illustrates methods of DNA sequencing and its application in plant, animal and medical sciences. It has two distinct sections. The one includes 2 chapters devoted to the DNA sequencing methods and the second includes 6 chapters focusing on various applications of this technology. The content of the articles presented in the book is guided by the knowledge and experience of the contributing authors. This book is intended to serve as an important resource and review to the researchers in the field of DNA sequencing. |
ngs ppt: Haze in the Grand Canyon National Research Council, Division on Earth and Life Studies, Commission on Geosciences, Environment and Resources, Board on Atmospheric Sciences and Climate, Board on Environmental Studies and Toxicology, Committee on Haze in National Parks and Wilderness Areas, 1990-02-01 This book presents working principles for assessing the relative importance of anthropogenic emission sources that contribute to haze in U.S. national parks and wilderness areas and discusses various alternative source control methods. Haze in the Grand Canyon evaluates and recommends strategies for improving critical scientific and technical gaps in the information and databases on haze. It examines such topics as methods for determining individual source contributions, regional and seasonal factors that affect haze, strategies for improving air quality models, the interactive role of photochemical exodants, and scientific and technological considerations in choosing emission control measures. |
ngs ppt: Diagnostics Stewardship in Molecular Microbiology: From at Home testing to NGS, An Issue of the Clinics in Laboratory Medicine, E-Book Jennifer Dien Bard, Esther Babady, 2024-02-05 In this issue of Clinics in Laboratory Medicine, guest editors Drs. Jennifer Dien Bard and Esther Babady bring their considerable expertise to the topic of Diagnostics Stewardship in Molecular Microbiology: From At-Home Testing to Next Generation Sequencing. Molecular testing for infectious diseases diagnostics is quickly expanding beyond clinical microbiology laboratories, while higher complexity tests based on next generation sequencing are now available for infectious diseases diagnosis. Diagnostic stewardship, led by microbiology experts in collaboration with clinicians and other healthcare workers, is critical in ensuring responsible and judicious use of these tests. In this issue, top experts in the field address practical challenges and provide guidance for diagnostic stewardship of molecular infectious disease diagnostics tests, from point-of-care to next generation sequencing. - Contains 10 relevant, practice-oriented topics including taking center stage: clinical laboratory leading diagnostic stewardship efforts; mapping out when and on whom high-dollar NGS tests should be ordered; working with LIS to maximize ordering and reporting of molecular microbiology results; present and future non-culture-based diagnostics: what are the potentials and considerations as it relates to stewardship and the role of the clinical microbiologist?; and more. - Provides in-depth clinical reviews on diagnostics stewardship in molecular microbiology, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews. |
ngs ppt: Bioinformatics: A Practical Handbook Of Next Generation Sequencing And Its Applications Lloyd Wai Yee Low, Martti Tapani Tammi, 2017-07-26 Rapid technological developments have led to increasingly efficient sequencing approaches. Next Generation Sequencing (NGS) is increasingly common and has become cost-effective, generating an explosion of sequenced data that need to be analyzed. The skills required to apply computational analysis to target research on a wide range of applications that include identifying causes of cancer, vaccine design, new antibiotics, drug development, personalized medicine and higher crop yields in agriculture are highly sought after.This invaluable book provides step-by-step guides to complex topics that make it easy for readers to perform essential analyses from raw sequenced data to answering important biological questions. It is an excellent hands-on material for teachers who conduct courses in bioinformatics and as a reference material for professionals. The chapters are written to be standalone recipes making it suitable for readers who wish to self-learn selected topics. Readers will gain skills necessary to work on sequenced data from NGS platforms and hence making themselves more attractive to employers who need skilled bioinformaticians to handle the deluge of data. |
ngs ppt: Knowledge Representation in the Social Semantic Web Katrin Weller, 2010-10-29 The main purpose of this book is to sum up the vital and highly topical research issue of knowledge representation on the Web and to discuss novel solutions by combining benefits of folksonomies and Web 2.0 approaches with ontologies and semantic technologies. The book contains an overview of knowledge representation approaches in past, present and future, introduction to ontologies, Web indexing and in first case the novel approaches of developing ontologies. |
ngs ppt: Data-Intensive Text Processing with MapReduce Jimmy Lin, Chris Dyer, 2022-05-31 Our world is being revolutionized by data-driven methods: access to large amounts of data has generated new insights and opened exciting new opportunities in commerce, science, and computing applications. Processing the enormous quantities of data necessary for these advances requires large clusters, making distributed computing paradigms more crucial than ever. MapReduce is a programming model for expressing distributed computations on massive datasets and an execution framework for large-scale data processing on clusters of commodity servers. The programming model provides an easy-to-understand abstraction for designing scalable algorithms, while the execution framework transparently handles many system-level details, ranging from scheduling to synchronization to fault tolerance. This book focuses on MapReduce algorithm design, with an emphasis on text processing algorithms common in natural language processing, information retrieval, and machine learning. We introduce the notion of MapReduce design patterns, which represent general reusable solutions to commonly occurring problems across a variety of problem domains. This book not only intends to help the reader think in MapReduce, but also discusses limitations of the programming model as well. Table of Contents: Introduction / MapReduce Basics / MapReduce Algorithm Design / Inverted Indexing for Text Retrieval / Graph Algorithms / EM Algorithms for Text Processing / Closing Remarks |
ngs ppt: Diagnostic Techniques for Semiconductor Materials Processing: Volume 406 Stella W. Pang, 1996-03-18 The fabrication of Si- and compound semiconductor-based devices involves a number of steps ranging from material growth to pattern definition by lithography, and ultimately, pattern transfer by etching/deposition. The key to device manufacturing, however, is reproducibility, low cost and high yield. Diagnostic techniques allow correlation between processing and actual device performance to be established. Researchers from universities, industry and government come together in this book to examine the advances in diagnostic techniques that provide critical information on structural, optical and electrical properties of semiconductor devices, as well as monitoring techniques for equipment/processes for control and feedback. The overriding goal is for rapid, accurate materials characterization, both in situ and ex situ. Topics include: in situ diagnostics; proximal probe microscopies; optical probes of devices and device properties; spectroscopic ellipsometry/structural diagnostics; and material analysis - X-ray techniques, strain measurements and passivation. |
ngs ppt: Molecular Epidemiology Paul A. Schulte, Frederica P. Perera, 2012-12-02 This book will serve as a primer for both laboratory and field scientists who are shaping the emerging field of molecular epidemiology. Molecular epidemiology utilizes the same paradigm as traditional epidemiology but uses biological markers to identify exposure, disease or susceptibility. Schulte and Perera present the epidemiologic methods pertinent to biological markers. The book is also designed to enumerate the considerations necessary for valid field research and provide a resource on the salient and subtle features of biological indicators. |
ngs ppt: Governing the Commons Elinor Ostrom, 2015-09-23 The governance of natural resources used by many individuals in common is an issue of increasing concern to policy analysts. Both state control and privatization of resources have been advocated, but neither the state nor the market have been uniformly successful in solving common pool resource problems. After critiquing the foundations of policy analysis as applied to natural resources, Elinor Ostrom here provides a unique body of empirical data to explore conditions under which common pool resource problems have been satisfactorily or unsatisfactorily solved. Dr Ostrom uses institutional analysis to explore different ways - both successful and unsuccessful - of governing the commons. In contrast to the proposition of the 'tragedy of the commons' argument, common pool problems sometimes are solved by voluntary organizations rather than by a coercive state. Among the cases considered are communal tenure in meadows and forests, irrigation communities and other water rights, and fisheries. |
ngs ppt: Bioinformatics: Sequences, Structures, Phylogeny Asheesh Shanker, 2018-10-13 This book provides a comprehensive overview of the concepts and approaches used for sequence, structure, and phylogenetic analysis. Starting with an introduction to the subject and intellectual property protection for bioinformatics, it guides readers through the latest sequencing technologies, sequence analysis, genomic variations, metagenomics, epigenomics, molecular evolution and phylogenetics, structural bioinformatics, protein folding, structure analysis and validation, drug discovery, reverse vaccinology, machine learning, application of R programming in biological data analysis, and the use of Linux in handling large data files. |
ngs ppt: Manual of Surveying Instructions Cadastral Survey (U.S.), United States. Bureau of Land Management. Wyoming State Office. Cadastral Survey, 2009 |
ngs ppt: Immune Infertility Walter K.H. Krause, Rajesh K. Naz, 2016-11-02 This book offers comprehensive coverage of both basic and clinical aspects of immune reactions responsible for infertility. It has four sections focusing on Sperm antigens, Antisperm antibodies (ASAs), Clinical impact of ASAs, and Immune contraception, and include contributions from leading experts in these fields. This new edition of the book offers a comprehensive update that reflects the very significant advances in reproductive immunology that have been achieved over the past five years, especially related to the sperm proteome, sperm-egg binding/fusion proteins, gene knockout studies, and immunocontraception. Reproductive immunology continues to be a fast-growing discipline in which new knowledge is emerging almost every day. Immune Infertility is a model source of vital and reliable information on the latest scientific developments in the field. It will be of value for clinicians, scientists, students, residents, and fellows working in reproductive biology, obstetrics and gynecology, and urology. |
ngs ppt: Antarctic Bibliography Stuart G. Hibben, 1997 |
ngs ppt: Annihilation of Caste B.R. Ambedkar, 2014-10-07 B.R. Ambedkar's Annihilation of Caste is one of the most important, yet neglected, works of political writing from India. Written in 1936, it is an audacious denunciation of Hinduism and its caste system. It offers a scholarly critique of Hindu scriptures, scriptures that sanction a rigidly hierarchical and iniquitous social system. Arundhati Roy introduces this extensively annotated edition in The Doctor and the Saint, examining the persistence of caste in modern India, and how the conflict between Ambedkar and Gandhi continues to resonate. Roy breathes new life into Ambedkar's anti-caste utopia, and says that without a Dalit revolution, India will continue to be hobbled by systemic inequality. |
ngs ppt: Introduction to Bioinformatics Stephen A. Krawetz, David D. Womble, 2003-01-31 to Bioinformatics A Theoretical and Practical Approach Edited by Stephen A. Krawetz, PhD Wayne State University School of Medicine, Detroit MI and David D. Womble, PhD Wayne State University School of Medicine, Detroit, MI ~ Springer Science+ ~ Business Media, LLC © 2003 Springer Science+Business Media New York Originally published by Humana Press !ne. in 2003 Softcover reprint of the hardcover 1 st edition 2003 humanapress.com Ali rights reserved. No part of this book may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording, or otherwise without written permission from the Publisher. Ali papers, comments, opinions, conclusions, or recommendations are those of the author(s), and do not necessarily reflect the views of the publisher. This publication is printed on acid-free paper. G) ANSI Z39.48-1984 (American Standards Institute) Permanence of Paper for Printed Library Materials. Production Editor: Mark J. Breaugh. Cover design by Patricia F. Cleary and Paul A. Thiessen. Cover illustration by Paul A. Thiessen, chemicalgraphics.com. |
ngs ppt: Gene Expression Analysis Nalini Raghavachari, Natalia Garcia-Reyero, 2025-02-03 This second edition volume expands on the previous edition with updates on the latest methodologies in the transcriptomics field. The chapters in this book cover topics such as spatial omics, long-read sequencing technology, tissue microarrays, analysis of saliva and extracellular vesicles, machine learning and artificial intelligence-based approaches for analysis of singe cells transcriptome, and large sets of data on multi-omics including transcriptomics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Gene Expression Analysis: Methods and Protocols, Second Edition is a valuable resource for advanced undergraduate and graduate students studying gene expression analysis, and scientists interested in learning more about this rapidly advancing field. |
ngs ppt: Pedagogy of the Oppressed Paulo Freire, 1972 |
ngs ppt: Van Buren County, Michigan, 1870 Census Index , 1991 |
ngs ppt: Mastering MIcrosoft VBA Guy Hart-Davis, 2006-01-18 VBA is used for writing macros, automating Office applications, and creating custom applications in Word, Excel, PowerPoint, Outlook, and Access Easily accessible by novice programmers, VBA is also powerful enough for IT professionals who need to create specialized business applications, generating wide interest Completely revised for the new versions of the language and the Office suite, this book is the most up-to-date VBA guide on the market Includes what everyone, from power users to system administrators and professional developers, needs to know Covers all Office products in depth |
ngs ppt: RNA Modifications Mary McMahon, 2022-06-18 This detailed book describes some of the most recent advances and up-to-date methodologies to detect, quantify, analyze, and elucidate the biological function of different types of RNA modifications. Importantly, the methodologies and tools described herein can be applied to a wide variety of organisms and can be used to address biological and clinical questions. Beginning with a section on bioinformatics tools, the collection continues with sections on detecting RNA modifications using Nanopore direct RNA sequencing, next-generation sequencing approaches, qPCR- and molecular biology-based methods, mass spectrometry- and NMR-based methods, as well as approaches to assess kinetics, determinants, and functions of RNA modifications. Written for the highly successful Methods in Molecular Biology series style, chapters include introduction to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, RNA Modifications: Methods and Protocols serves as an ideal guide for those working directly in the fields of epitranscriptomics and post-transcriptional gene regulation, as well as for scientists and clinicians interested in bioinformatic tools to study RNA modifications and techniques to dissect their roles in physiology and disease. /divChapter 20 is available open access under a CC BY 4.0 license. |
ngs ppt: Plant Omics: Trends and Applications Khalid Rehman Hakeem, Hüseyin Tombuloğlu, Güzin Tombuloğlu, 2016-08-23 To comprehend the organizational principle of cellular functions at diff erent levels, an integrative approach with large-scale experiments, the so-called ‘omics’ data including genomics, transcriptomics, proteomics, and metabolomics, is needed. Omics aims at the collective characterization and quantifi cation of pools of biological molecules that translate into the structure, function, and dynamics of an organism or organisms. Currently, omics is an essential tool to understand the molecular systems that underlie various plant functions. Furthermore, in several plant species, the development of omicsresources has progressed to address the particular biological properties of individual species. Integration of knowledge from omics-based research is an emerging issue as researchers seek to identify significance, gain biological insights and promote translational research. From these perspectives, we intend to provide the emerging aspects of plant systems research based on omics and bioinformatics analyses together with their associated resources and technological advances. Th e present book covers a wide range of omics topics, and discusses the latest trends and application area of plant sciences. In this volume, we have highlighted the working solutions as well as open problems and future challenges in plant omics studies. We believe that this book will initiate and introduce readers to state-of-the-art developments and trends in omics-driven research. |
ngs ppt: Offshore Tax Evasion: pages 1002-2154 United States. Congress. Senate. Committee on Homeland Security and Governmental Affairs. Permanent Subcommittee on Investigations, 2014 |
ngs ppt: Single Nucleotide Polymorphisms Pui-Yan Kwok, 2008-02-04 A comprehensive collection of readily reproducible techniques for the difficult process of single nucleotide polymorphisms (SNP) discovery and genotyping. These cutting-edge protocols for mutation/SNP detection utilize denaturing high-performance liquid chromatography (dHPLC), single-strand conformation polymorphism (SSCP), conformation-sensitive gel electrophoresis (CSGE), chemical cleavage, and direct sequencing. Equally powerful and up-to-date methods are given for genotyping SNPs, including molecular beacons, the Taqman assay, single-base extension approaches, pyrosequencing, ligation, the Invader assay, and primer extension with mass spectrometry detection. |
ngs ppt: Storing Digital Binary Data in Cellular DNA Rocky Termanini, 2020-08-18 Storing Digital Binary Data into Cellular DNA demonstrates how current digital information storage systems have short longevity and limited capacity, also pointing out that their production and consumption of data exceeds supply. Author Rocky Termanini explains the DNA system and how it encodes vast amounts of data, then presents information on the emergence of DNA as a storage technology for the ever-growing stream of data being produced and consumed. The book will be of interest to a range of readers looking to understand this game-changing technology, including researchers in computer science, biomedical engineers, geneticists, physicians, clinicians, law enforcement and cybersecurity experts. - Presents a comprehensive reference on the fascinating and emerging technology of DNA storage - Helps readers understand key concepts on how DNA works as an information storage system - Provides readers with key information on the technologies used to work with DNA data encoding, such as CRISPR - Covers emerging areas of application and ethical concern, such as Smart Cities, cybercrime and cyberwarfare - Includes coverage of synthesizing DNA-encoded data, sequencing DNA-encoded data, and fusing DNA with Digital Immunity Ecosystems (DIE) |
如何解读 NGS 测序的核心原理? - 知乎
NGS应用已不再局限于全基因组分析,对于基础基因组学和疾病研究的最新进步更是影响深远。以下是一些有用的参考资料,可以帮助你更好地了解某个主题:www.sigmaaldrich.cn. NGS方法 …
Heads and tails when using NGS - Beginners - American Distilling ...
Aug 5, 2018 · Assuming decent quality NGS, any potential spirit heads cut will be minuscule compared to your gin heads cut (initial juniper bitterness and louching) in volume. Not to …
Vinegar manufacturer questions on NGS safety - Safety - American ...
Jul 6, 2023 · 3. Even if you do dilute the NGS the vapors above the liquid can be flammable. I once saw a wine tank explode when the lid was welded while there was wine in the bottom of …
NGS suppliers - Gin - American Distilling Institute Forums
Dec 31, 2014 · Wheat NGS is particularly what I am interested in. After a recent visit to London and speaking with many of the smaller craft gin distillers over there they seem to prefer it, …
Do I need a DSP license to purchase, brand, and sell NGS
Mar 29, 2016 · So, based upon bullet 1 & 3 above, you could bring in NGS and bottle, provided you get a Basic Permit. However, without at least a Basic Permit, you cannot do what you ask. …
NGS - Vodka - American Distilling Institute Forums
Oct 19, 2016 · So in other words, re-bubbler X claims that its ok to re-bubble NGS becuase re-bubbler Y is doing it, and re-bubbler Y is saying exactally the same thing about re-bubbler X. …
NGS or GNS? - General Discussion - American Distilling Institute …
Mar 3, 2013 · "Grain" is an attributive noun which can apply to either "spirit" or "neutral spirit", thus both GNS and NGS are grammatically correct. However, the term "neutral grain spirit" does …
Blending Our Vodka and NGS Labeling - Vodka - American …
Dec 5, 2017 · Dhdunbar is correct, you will need to submit a formula if you buy or make NGS that is not designated as vodka at the time of production, and you want to change it to vodka. And …
Achieving 95% without NGS - American Distilling Institute Forums
Nov 19, 2014 · Even starting with NGS diluted down to 50% abv it is still not practical to to get an average 95% output on a 6 plate still. I think the key to your question is that by starting with …
Full Distillery or Part-Out / NGS, BOTTLES, STILLS
Aug 13, 2024 · Hey! I have a distillery in Northern Arizona with 27 account around Flagstaff. I am happy to sell the entire company or just individual items. Long story short, moving to Australia. …
如何解读 NGS 测序的核心原理? - 知乎
NGS应用已不再局限于全基因组分析,对于基础基因组学和疾病研究的最新进步更是影响深远。以下是一些有用的参考资料,可以帮助你更好地了解某个主题:www.sigmaaldrich.cn. NGS方法 …
Heads and tails when using NGS - Beginners - American Distilling ...
Aug 5, 2018 · Assuming decent quality NGS, any potential spirit heads cut will be minuscule compared to your gin heads cut (initial juniper bitterness and louching) in volume. Not to …
Vinegar manufacturer questions on NGS safety - Safety - American ...
Jul 6, 2023 · 3. Even if you do dilute the NGS the vapors above the liquid can be flammable. I once saw a wine tank explode when the lid was welded while there was wine in the bottom of …
NGS suppliers - Gin - American Distilling Institute Forums
Dec 31, 2014 · Wheat NGS is particularly what I am interested in. After a recent visit to London and speaking with many of the smaller craft gin distillers over there they seem to prefer it, …
Do I need a DSP license to purchase, brand, and sell NGS
Mar 29, 2016 · So, based upon bullet 1 & 3 above, you could bring in NGS and bottle, provided you get a Basic Permit. However, without at least a Basic Permit, you cannot do what you ask. …
NGS - Vodka - American Distilling Institute Forums
Oct 19, 2016 · So in other words, re-bubbler X claims that its ok to re-bubble NGS becuase re-bubbler Y is doing it, and re-bubbler Y is saying exactally the same thing about re-bubbler X. …
NGS or GNS? - General Discussion - American Distilling Institute …
Mar 3, 2013 · "Grain" is an attributive noun which can apply to either "spirit" or "neutral spirit", thus both GNS and NGS are grammatically correct. However, the term "neutral grain spirit" does …
Blending Our Vodka and NGS Labeling - Vodka - American …
Dec 5, 2017 · Dhdunbar is correct, you will need to submit a formula if you buy or make NGS that is not designated as vodka at the time of production, and you want to change it to vodka. And …
Achieving 95% without NGS - American Distilling Institute Forums
Nov 19, 2014 · Even starting with NGS diluted down to 50% abv it is still not practical to to get an average 95% output on a 6 plate still. I think the key to your question is that by starting with …
Full Distillery or Part-Out / NGS, BOTTLES, STILLS
Aug 13, 2024 · Hey! I have a distillery in Northern Arizona with 27 account around Flagstaff. I am happy to sell the entire company or just individual items. Long story short, moving to Australia. …