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| michael borenstein meta analysis: Introduction to Meta-Analysis Michael Borenstein, Larry V. Hedges, Julian P. T. Higgins, Hannah R. Rothstein, 2011-08-24 This book provides a clear and thorough introduction to meta-analysis, the process of synthesizing data from a series of separate studies. Meta-analysis has become a critically important tool in fields as diverse as medicine, pharmacology, epidemiology, education, psychology, business, and ecology. Introduction to Meta-Analysis: Outlines the role of meta-analysis in the research process Shows how to compute effects sizes and treatment effects Explains the fixed-effect and random-effects models for synthesizing data Demonstrates how to assess and interpret variation in effect size across studies Clarifies concepts using text and figures, followed by formulas and examples Explains how to avoid common mistakes in meta-analysis Discusses controversies in meta-analysis Features a web site with additional material and exercises A superb combination of lucid prose and informative graphics, written by four of the world’s leading experts on all aspects of meta-analysis. Borenstein, Hedges, Higgins, and Rothstein provide a refreshing departure from cookbook approaches with their clear explanations of the what and why of meta-analysis. The book is ideal as a course textbook or for self-study. My students, who used pre-publication versions of some of the chapters, raved about the clarity of the explanations and examples. David Rindskopf, Distinguished Professor of Educational Psychology, City University of New York, Graduate School and University Center, & Editor of the Journal of Educational and Behavioral Statistics. The approach taken by Introduction to Meta-analysis is intended to be primarily conceptual, and it is amazingly successful at achieving that goal. The reader can comfortably skip the formulas and still understand their application and underlying motivation. For the more statistically sophisticated reader, the relevant formulas and worked examples provide a superb practical guide to performing a meta-analysis. The book provides an eclectic mix of examples from education, social science, biomedical studies, and even ecology. For anyone considering leading a course in meta-analysis, or pursuing self-directed study, Introduction to Meta-analysis would be a clear first choice. Jesse A. Berlin, ScD Introduction to Meta-Analysis is an excellent resource for novices and experts alike. The book provides a clear and comprehensive presentation of all basic and most advanced approaches to meta-analysis. This book will be referenced for decades. Michael A. McDaniel, Professor of Human Resources and Organizational Behavior, Virginia Commonwealth University |
| michael borenstein meta analysis: Common Mistakes in Meta-Analysis Michael Borenstein, 2019-08-15 |
| michael borenstein meta analysis: Publication Bias in Meta-Analysis Hannah R. Rothstein, Alexander J. Sutton, Michael Borenstein, 2005-11-18 Publication bias is the tendency to decide to publish a study based on the results of the study, rather than on the basis of its theoretical or methodological quality. It can arise from selective publication of favorable results, or of statistically significant results. This threatens the validity of conclusions drawn from reviews of published scientific research. Meta-analysis is now used in numerous scientific disciplines, summarizing quantitative evidence from multiple studies. If the literature being synthesised has been affected by publication bias, this in turn biases the meta-analytic results, potentially producing overstated conclusions. Publication Bias in Meta-Analysis examines the different types of publication bias, and presents the methods for estimating and reducing publication bias, or eliminating it altogether. Written by leading experts, adopting a practical and multidisciplinary approach. Provides comprehensive coverage of the topic including: Different types of publication bias, Mechanisms that may induce them, Empirical evidence for their existence, Statistical methods to address them, Ways in which they can be avoided. Features worked examples and common data sets throughout. Explains and compares all available software used for analysing and reducing publication bias. Accompanied by a website featuring software, data sets and further material. Publication Bias in Meta-Analysis adopts an inter-disciplinary approach and will make an excellent reference volume for any researchers and graduate students who conduct systematic reviews or meta-analyses. University and medical libraries, as well as pharmaceutical companies and government regulatory agencies, will also find this invaluable. |
| michael borenstein meta analysis: Handbook of Meta-analysis in Ecology and Evolution Julia Koricheva, Jessica Gurevitch, Kerrie Mengersen, 2013-04-21 Meta-analysis is a powerful statistical methodology for synthesizing research evidence across independent studies. This is the first comprehensive handbook of meta-analysis written specifically for ecologists and evolutionary biologists, and it provides an invaluable introduction for beginners as well as an up-to-date guide for experienced meta-analysts. The chapters, written by renowned experts, walk readers through every step of meta-analysis, from problem formulation to the presentation of the results. The handbook identifies both the advantages of using meta-analysis for research synthesis and the potential pitfalls and limitations of meta-analysis (including when it should not be used). Different approaches to carrying out a meta-analysis are described, and include moment and least-square, maximum likelihood, and Bayesian approaches, all illustrated using worked examples based on real biological datasets. This one-of-a-kind resource is uniquely tailored to the biological sciences, and will provide an invaluable text for practitioners from graduate students and senior scientists to policymakers in conservation and environmental management. Walks you through every step of carrying out a meta-analysis in ecology and evolutionary biology, from problem formulation to result presentation Brings together experts from a broad range of fields Shows how to avoid, minimize, or resolve pitfalls such as missing data, publication bias, varying data quality, nonindependence of observations, and phylogenetic dependencies among species Helps you choose the right software Draws on numerous examples based on real biological datasets |
| michael borenstein meta analysis: The Handbook of Research Synthesis and Meta-Analysis Harris Cooper, Larry V. Hedges, Jeffrey C. Valentine, 2009-02-05 Praise for the first edition: The Handbook is a comprehensive treatment of literature synthesis and provides practical advice for anyone deep in the throes of, just teetering on the brink of, or attempting to decipher a meta-analysis. Given the expanding application and importance of literature synthesis, understanding both its strengths and weaknesses is essential for its practitioners and consumers. This volume is a good beginning for those who wish to gain that understanding. —Chance Meta-analysis, as the statistical analysis of a large collection of results from individual studies is called, has now achieved a status of respectability in medicine. This respectability, when combined with the slight hint of mystique that sometimes surrounds meta-analysis, ensures that results of studies that use it are treated with the respect they deserve....The Handbook of Research Synthesis is one of the most important publications in this subject both as a definitive reference book and a practical manual.—British Medical Journal When the first edition of The Handbook of Research Synthesis was published in 1994, it quickly became the definitive reference for researchers conducting meta-analyses of existing research in both the social and biological sciences. In this fully revised second edition, editors Harris Cooper, Larry Hedges, and Jeff Valentine present updated versions of the Handbook's classic chapters, as well as entirely new sections reporting on the most recent, cutting-edge developments in the field. Research synthesis is the practice of systematically distilling and integrating data from a variety of sources in order to draw more reliable conclusions about a given question or topic. The Handbook of Research Synthesis and Meta-Analysis draws upon years of groundbreaking advances that have transformed research synthesis from a narrative craft into an important scientific process in its own right. Cooper, Hedges, and Valentine have assembled leading authorities in the field to guide the reader through every stage of the research synthesis process—problem formulation, literature search and evaluation, statistical integration, and report preparation. The Handbook of Research Synthesis and Meta-Analysis incorporates state-of-the-art techniques from all quantitative synthesis traditions. Distilling a vast technical literature and many informal sources, the Handbook provides a portfolio of the most effective solutions to the problems of quantitative data integration. Among the statistical issues addressed by the authors are the synthesis of non-independent data sets, fixed and random effects methods, the performance of sensitivity analyses and model assessments, and the problem of missing data. The Handbook of Research Synthesis and Meta-Analysis also provides a rich treatment of the non-statistical aspects of research synthesis. Topics include searching the literature, and developing schemes for gathering information from study reports. Those engaged in research synthesis will also find useful advice on how tables, graphs, and narration can be used to provide the most meaningful communication of the results of research synthesis. In addition, the editors address the potentials and limitations of research synthesis, and its future directions. The past decade has been a period of enormous growth in the field of research synthesis. The second edition Handbook thoroughly revises original chapters to assure that the volume remains the most authoritative source of information for researchers undertaking meta-analysis today. In response to the increasing use of research synthesis in the formation of public policy, the second edition includes a new chapter on both the strengths and limitations of research synthesis in policy debates |
| michael borenstein meta analysis: Systematic Reviews in Health Research Matthias Egger, Julian P. T. Higgins, George Davey Smith, 2022-06-13 Systematic Reviews in Health Research Explore the cutting-edge of systematic reviews in healthcare In this Third Edition of the classic Systematic Reviews textbook, now titled Systematic Reviews in Health Research, a team of distinguished researchers deliver a comprehensive and authoritative guide to the rapidly evolving area of systematic reviews and meta-analysis. The book demonstrates why systematic reviews—when conducted properly—provide the highest quality evidence on clinical and public health interventions and shows how they contribute to inference in many other contexts. The new edition reflects the broad role of systematic reviews, including: Twelve new chapters, covering additional study designs, methods and software, for example, on genetic association studies, prediction models, prevalence studies, network and dose-response meta-analysis Thorough update of 15 chapters focusing on systematic reviews of interventions Access to a companion website offering supplementary materials and practical exercises (www.systematic-reviews3.org) A key text for health researchers, Systematic Reviews in Health Research is also an indispensable resource for practitioners, students, and instructors in the health sciences needing to understand research synthesis. |
| michael borenstein meta analysis: Research Synthesis and Meta-Analysis Harris Cooper, 2015-12-24 The Fifth Edition of Harris Cooper′s bestselling text offers practical advice on how to conduct a synthesis of research in the social, behavioral, and health sciences. The book is written in plain language with four running examples drawn from psychology, education, and health science. With ample coverage of literature searching and the technical aspects of meta-analysis, this one-of-a-kind book applies the basic principles of sound data gathering to the task of producing a comprehensive assessment of existing research. |
| michael borenstein meta analysis: Statistical Methods for Meta-Analysis Larry V. Hedges, Ingram Olkin, 2014-06-28 The main purpose of this book is to address the statistical issues for integrating independent studies. There exist a number of papers and books that discuss the mechanics of collecting, coding, and preparing data for a meta-analysis , and we do not deal with these. Because this book concerns methodology, the content necessarily is statistical, and at times mathematical. In order to make the material accessible to a wider audience, we have not provided proofs in the text. Where proofs are given, they are placed as commentary at the end of a chapter. These can be omitted at the discretion of the reader.Throughout the book we describe computational procedures whenever required. Many computations can be completed on a hand calculator, whereas some require the use of a standard statistical package such as SAS, SPSS, or BMD. Readers with experience using a statistical package or who conduct analyses such as multiple regression or analysis of variance should be able to carry out the analyses described with the aid of a statistical package. |
| michael borenstein meta analysis: Introduction to Meta-Analysis Michael Borenstein, Larry V. Hedges, Julian P. T. Higgins, Hannah R. Rothstein, 2021-04-20 A clear and thorough introduction to meta-analysis, the process of synthesizing data from a series of separate studies The first edition of this text was widely acclaimed for the clarity of the presentation, and quickly established itself as the definitive text in this field. The fully updated second edition includes new and expanded content on avoiding common mistakes in meta-analysis, understanding heterogeneity in effects, publication bias, and more. Several brand-new chapters provide a systematic how to approach to performing and reporting a meta-analysis from start to finish. Written by four of the world's foremost authorities on all aspects of meta-analysis, the new edition: Outlines the role of meta-analysis in the research process Shows how to compute effects sizes and treatment effects Explains the fixed-effect and random-effects models for synthesizing data Demonstrates how to assess and interpret variation in effect size across studies Explains how to avoid common mistakes in meta-analysis Discusses controversies in meta-analysis Includes access to a companion website containing videos, spreadsheets, data files, free software for prediction intervals, and step-by-step instructions for performing analyses using Comprehensive Meta-Analysis (CMA) Download videos, class materials, and worked examples at www.Introduction-to-Meta-Analysis.com This book offers the reader a unified framework for thinking about meta-analysis, and then discusses all elements of the analysis within that framework. The authors address a series of common mistakes and explain how to avoid them. As the editor-in-chief of the American Psychologist and former editor of Psychological Bulletin, I can say without hesitation that the quality of manuscript submissions reporting meta-analyses would be vastly better if researchers read this book. —Harris Cooper, Hugo L. Blomquist Distinguished Professor Emeritus of Psychology and Neuroscience, Editor-in-chief of the American Psychologist, former editor of Psychological Bulletin A superb combination of lucid prose and informative graphics, the authors provide a refreshing departure from cookbook approaches with their clear explanations of the what and why of meta-analysis. The book is ideal as a course textbook or for self-study. My students raved about the clarity of the explanations and examples. —David Rindskopf, Distinguished Professor of Educational Psychology, City University of New York, Graduate School and University Center, & Editor of the Journal of Educational and Behavioral Statistics The approach taken by Introduction to Meta-analysis is intended to be primarily conceptual, and it is amazingly successful at achieving that goal. The reader can comfortably skip the formulas and still understand their application and underlying motivation. For the more statistically sophisticated reader, the relevant formulas and worked examples provide a superb practical guide to performing a meta-analysis. The book provides an eclectic mix of examples from education, social science, biomedical studies, and even ecology. For anyone considering leading a course in meta-analysis, or pursuing self-directed study, Introduction to Meta-analysis would be a clear first choice. —Jesse A. Berlin, ScD |
| michael borenstein meta analysis: Practical Meta-Analysis Mark W. Lipsey, David B. Wilson, 2001 By integrating and translating the current methodological and statistical work into a practical guide, the authors of this text provide readers with a state-of-the-art introduction to the various approaches to doing meta-analysis. |
| michael borenstein meta analysis: Conducting Meta-Analysis Using SAS Winfred Arthur, Jr., Winston Bennett, Allen I. Huffcutt, 2001-06 Designed to teach the reader about meta-analysis and show them how to conduct one using SAS. Its focus is more applied and practical than theoretical and will include additional programming codes and examples. Web site to house program code and sample ou |
| michael borenstein meta analysis: How Science Takes Stock Morton Hunt, 1999-10-21 Policymakers, medical practitioners, and the public alike face an increasingly bewildering flood of new and often contradictory scientific studies on almost every topic. Whether the issue is the the best treatment for breast cancer, the need for prenatal food programs to improve the health of poor infants and mothers, or the ability of women to succeed in scientific professions, the healthy growth of modern science has at times done more to stir up controversy than to establish reliable knowledge. But now scientists in several fields have developed a sophisticated new methodology called meta-analysis to address this problem. By numerically combining diverse research findings on a single question, meta-analysis can be used to identify their central tendency and reach conclusions far more reliable than those of any single investigation. How Science Takes Stock vividly tells the story of meta-analysis through the eyes of its architects and champions, and chronicles its history, techniques, achievements, and controversies. Noted science author Morton Hunt visits key practitioners and recounts their use of meta-analysis to resolve important scientific puzzles and longstanding debates. Does psychotherapy work, and if so what form works best? Does spending federal money on education really improve student performance? Can a single enzyme significantly decrease the risk of heart attack? Do boot camps reduce juvenile delinquency? With each account, Hunt illustrates the major components of the meta-analytic method, reveals strategies for resolving practical and theoretical problems, and discusses the impact of meta-analysis on the science and policy communities. In many cases, he demonstrates how meta-analysts have gone a step further to determine the causes of earlier discrepancies. In this way they not only identify successful approaches to the question at hand, but also clarify the conditions under which they will work best. Hunt also portrays the important but frequently controversial business of doing meta-analysis for legislators and government agencies, particularly in sensitive areas of social policy. How Science Takes Stock demonstrates how the statistical techniques of meta-analysis produce more accurate data than the standard literature review or the old-fashioned process of tallying up the results of each scientific study as if they were votes in an election to decide the truth. Hunt also addresses issues of quality control in each phase of the meta-analytic process, and answers skeptics who claim that the dissimilarities between studies are often too significant for meta-analysis to be any more than an apples and oranges approach. This volume conveys the power of meta-analysis to help social policymakers and health professionals resolve their most pressing problems. How Science Takes Stock concludes with a discussion of the future of meta-analysis that examines its potential for further refinements, its growth in the scientific literature, and exciting new possibilities for its future use. An appendix by meta-analysis expert Harris Cooper offers some finer points on the mechanics of conducting a meta-analytic investigation. |
| michael borenstein meta analysis: Cochrane Handbook for Systematic Reviews of Interventions Julian P. T. Higgins, Sally Green, 2008-11-24 Healthcare providers, consumers, researchers and policy makers are inundated with unmanageable amounts of information, including evidence from healthcare research. It has become impossible for all to have the time and resources to find, appraise and interpret this evidence and incorporate it into healthcare decisions. Cochrane Reviews respond to this challenge by identifying, appraising and synthesizing research-based evidence and presenting it in a standardized format, published in The Cochrane Library (www.thecochranelibrary.com). The Cochrane Handbook for Systematic Reviews of Interventions contains methodological guidance for the preparation and maintenance of Cochrane intervention reviews. Written in a clear and accessible format, it is the essential manual for all those preparing, maintaining and reading Cochrane reviews. Many of the principles and methods described here are appropriate for systematic reviews applied to other types of research and to systematic reviews of interventions undertaken by others. It is hoped therefore that this book will be invaluable to all those who want to understand the role of systematic reviews, critically appraise published reviews or perform reviews themselves. |
| michael borenstein meta analysis: Network Meta-Analysis for Decision-Making Sofia Dias, A. E. Ades, Nicky J. Welton, Jeroen P. Jansen, Alexander J. Sutton, 2018-03-19 A practical guide to network meta-analysis with examples and code In the evaluation of healthcare, rigorous methods of quantitative assessment are necessary to establish which interventions are effective and cost-effective. Often a single study will not provide the answers and it is desirable to synthesise evidence from multiple sources, usually randomised controlled trials. This book takes an approach to evidence synthesis that is specifically intended for decision making when there are two or more treatment alternatives being evaluated, and assumes that the purpose of every synthesis is to answer the question for this pre-identified population of patients, which treatment is 'best'? A comprehensive, coherent framework for network meta-analysis (mixed treatment comparisons) is adopted and estimated using Bayesian Markov Chain Monte Carlo methods implemented in the freely available software WinBUGS. Each chapter contains worked examples, exercises, solutions and code that may be adapted by readers to apply to their own analyses. This book can be used as an introduction to evidence synthesis and network meta-analysis, its key properties and policy implications. Examples and advanced methods are also presented for the more experienced reader. Methods used throughout this book can be applied consistently: model critique and checking for evidence consistency are emphasised. Methods are based on technical support documents produced for NICE Decision Support Unit, which support the NICE Methods of Technology Appraisal. Code presented is also the basis for the code used by the ISPOR Task Force on Indirect Comparisons. Includes extensive carefully worked examples, with thorough explanations of how to set out data for use in WinBUGS and how to interpret the output. Network Meta-Analysis for Decision Making will be of interest to decision makers, medical statisticians, health economists, and anyone involved in Health Technology Assessment including the pharmaceutical industry. |
| michael borenstein meta analysis: Introduction to Meta-Analysis , 2009-04-13 This text provides a concise and clearly presented discussion of all the elements in a meta-analysis. It is illustrated with worked examples throughout, with visual explanations, using screenshots from Excel spreadsheets and computer programs such as Comprehensive Meta-Analysis (CMA) or Strata. |
| michael borenstein meta analysis: Bariatric Endoscopy Christopher C. Thompson, 2025-02-11 The issues presented in this text have particular relevance in our obesogenic society. Over one-third of the adult population in the United States suffers from obesity, and it is now apparent that this epidemic is progressively becoming global in scale. Lifestyle modification, dietary programs, and medical therapies have an important role, however, alone they are not adequate for many patients. Bariatric surgery has provided an effective alternative for achieving durable weight loss in many patients with morbid obesity, and there are currently several types of surgery being employed for weight loss and the treatment of obesity associated comorbid illness. It is estimated that over 200,000 bariatric procedures are performed annually in the United States. The most common are Roux-en-Y gastric bypass and sleeve gastrectomy among others. Each of these surgeries may also have important variations, and are in turn associated with unique gastrointestinal complications. Additionally, there are new medications and emerging endobariatric therapies that are gaining wide acceptance, and offering less invasive alternatives to this struggling population. This textbook on obesity management and bariatric endoscopy is the work of a multidisciplinary group of international experts and is intended to serve as a comprehensive guide to the endoscopic management of patients with obesity. It is divided into three main sections: I. Obesity Overview and Medical Management; II. Traditional Bariatric Surgery and Endoscopic Management of Complications; and III. Endoscopic Bariatric Therapies. Epidemiology, pharmacological and surgical treatment of obesity, surgical anatomy, post-operative complications, endoscopic treatment of complications, and endoscopic bariatric therapies are covered in-depth. In addition to thoroughly revised chapters from the previous edition, the latest volume includes more than 10 new chapters. Clinical gastroenterologists, gastroenterologists in training, and surgeons with a special interest in obesity management will find this book to be of practical importance. |
| michael borenstein meta analysis: Power and Precision , 2001 |
| michael borenstein meta analysis: Handbook of Meta-Analysis Christopher H. Schmid, Theo Stijnen, Ian White, 2020-09-07 Meta-analysis is the application of statistics to combine results from multiple studies and draw appropriate inferences. Its use and importance have exploded over the last 25 years as the need for a robust evidence base has become clear in many scientific areas, including medicine and health, social sciences, education, psychology, ecology, and economics. Recent years have seen an explosion of methods for handling complexities in meta-analysis, including explained and unexplained heterogeneity between studies, publication bias, and sparse data. At the same time, meta-analysis has been extended beyond simple two-group comparisons of continuous and binary outcomes to comparing and ranking the outcomes from multiple groups, to complex observational studies, to assessing heterogeneity of effects, and to survival and multivariate outcomes. Many of these methods are statistically complex and are tailored to specific types of data. Key features Rigorous coverage of the full range of current statistical methodology used in meta-analysis Comprehensive, coherent, and unified overview of the statistical foundations behind meta-analysis Detailed description of the primary methods for both univariate and multivariate data Computer code to reproduce examples in chapters Thorough review of the literature with thousands of references Applications to specific types of biomedical and social science data Supplementary website with code, data, sample chapters, and errata This book is for a broad audience of graduate students, researchers, and practitioners interested in the theory and application of statistical methods for meta-analysis. It is written at the level of graduate courses in statistics, but will be of interest to and readable for quantitative scientists from a range of disciplines. The book can be used as a graduate level textbook, as a general reference for methods, or as an introduction to specialized topics using state-of-the art methods. |
| michael borenstein meta analysis: Synthesizing Research Harris M. Cooper, 1998-01-15 This text is appropriate for anyone who has taken an introductory research methods course and it includes updated coverage of report writing, validity issues, study retrieval and evaluation of research studies. |
| michael borenstein meta analysis: Mergers, Merger Control, and Remedies John Kwoka, 2015 A comprehensive analysis of merger outcomes based on all empirical studies, with an assessment of the effectiveness of antitrust policy toward mergers. In recent decades, antitrust investigations and cases targeting mergers—including those involving Google, Ticketmaster, and much of the domestic airline industry—have reshaped industries and changed business practices profoundly. And yet there has been a relative dearth of detailed evaluations of the effects of mergers and the effectiveness of merger policy. In this book, John Kwoka, a noted authority on industrial organization, examines all reliable empirical studies of the effect of specific mergers and develops entirely new information about the policies and remedies of antitrust agencies regarding these mergers. Combined with data on outcomes, this policy information enables analysis of, and creates new insights into, mergers, merger policies, and the effectiveness of remedies in preventing anticompetitive outcomes. After an overview of mergers, merger policy, and a common approach to merger analysis, Kwoka offers a detailed analysis of the studied mergers, relevant policies, and chosen remedies. Kwoka finds, first and foremost, that most of the studied mergers resulted in competitive harm, usually in the form of higher product prices but also with respect to various non-price outcomes. Other important findings include the fact that joint ventures and code sharing arrangements do not result in such harm and that policies intended to remedy mergers—especially conduct remedies—are not generally effective in restraining price increases. The book's uniquely comprehensive analysis advances our understanding of merger decisions and policies, suggests policy improvements for competition agencies and remedies, and points the way to future research. |
| michael borenstein meta analysis: The Handbook of Research Synthesis Harris Cooper, Larry V. Hedges, 1993-11-23 “The Handbook is a comprehensive treatment of literature synthesis and provides practical advice for anyone deep in the throes of, just teetering on the brink of, or attempting to decipher a meta-analysis. Given the expanding application and importance of literature synthesis, understanding both its strengths and weaknesses is essential for its practitioners and consumers. This volume is a good beginning for those who wish to gain that understanding.” —Chance “Meta-analysis, as the statistical analysis of a large collection of results from individual studies is called, has now achieved a status of respectability in medicine. This respectability, when combined with the slight hint of mystique that sometimes surrounds meta-analysis, ensures that results of studies that use it are treated with the respect they deserve....The Handbook of Research Synthesis is one of the most important publications in this subject both as a definitive reference book and a practical manual.”—British Medical Journal The Handbook of Research Synthesis is the definitive reference and how-to manual for behavioral and medical scientists applying the craft of research synthesis. It draws upon twenty years of ground-breaking advances that have transformed the practice of synthesizing research literature from an art into a scientific process in its own right. Editors Harris Cooper and Larry V. Hedges have brought together leading authorities to guide the reader through every stage of the research synthesis process—problem formulation, literature search and evaluation, statistical integration, and report preparation. The Handbook of Research Synthesis incorporates in a single volume state-of-the-art techniques from all quantitative synthesis traditions, including Bayesian inference and the meta-analytic approaches. Distilling a vast technical literature and many informal sources, the Handbook provides a portfolio of the most effective solutions to problems of quantitative data integration. The Handbook of Research Synthesis also provides a rich treatment of the non-statistical aspects of research synthesis. Topics include searching the literature, managing reference databases and registries, and developing coding schemes. Those engaged in research synthesis will also find useful advice on how tables, graphs, and narration can be deployed to provide the most meaningful communication of the results of research synthesis. The Handbook of Research Synthesis is an illuminating compilation of practical instruction, theory, and problem solving. It provides an accumulation of knowledge about the craft of reviewing a scientific literature that can be found in no other single source. The Handbook offers the reader thorough instruction in the skills necessary to conduct powerful research syntheses meeting the highest standards of objectivity, systematicity, and rigor demanded of scientific enquiry. This definitive work will represent the state of the art in research synthesis for years to come. |
| michael borenstein meta analysis: Applied Meta-Analysis with R and Stata Ding-Geng (Din) Chen, Karl E. Peace, 2021-03-30 Review of the First Edition: The authors strive to reduce theory to a minimum, which makes it a self-learning text that is comprehensible for biologists, physicians, etc. who lack an advanced mathematics background. Unlike in many other textbooks, R is not introduced with meaningless toy examples; instead the reader is taken by the hand and shown around some analyses, graphics, and simulations directly relating to meta-analysis... A useful hands-on guide for practitioners who want to familiarize themselves with the fundamentals of meta-analysis and get started without having to plough through theorems and proofs. —Journal of Applied Statistics Statistical Meta-Analysis with R and Stata, Second Edition provides a thorough presentation of statistical meta-analyses (MA) with step-by-step implementations using R/Stata. The authors develop analysis step by step using appropriate R/Stata functions, which enables readers to gain an understanding of meta-analysis methods and R/Stata implementation so that they can use these two popular software packages to analyze their own meta-data. Each chapter gives examples of real studies compiled from the literature. After presenting the data and necessary background for understanding the applications, various methods for analyzing meta-data are introduced. The authors then develop analysis code using the appropriate R/Stata packages and functions. What’s New in the Second Edition: Adds Stata programs along with the R programs for meta-analysis Updates all the statistical meta-analyses with R/Stata programs Covers fixed-effects and random-effects MA, meta-regression, MA with rare-event, and MA-IPD vs MA-SS Adds five new chapters on multivariate MA, publication bias, missing data in MA, MA in evaluating diagnostic accuracy, and network MA Suitable as a graduate-level text for a meta-data analysis course, the book is also a valuable reference for practitioners and biostatisticians (even those with little or no experience in using R or Stata) in public health, medical research, governmental agencies, and the pharmaceutical industry. |
| michael borenstein meta analysis: Meta Analysis Elena Kulinskaya, Stephan Morgenthaler, Robert G. Staudte, 2008-04-15 Meta Analysis: A Guide to Calibrating and Combining Statistical Evidence acts as a source of basic methods for scientists wanting to combine evidence from different experiments. The authors aim to promote a deeper understanding of the notion of statistical evidence. The book is comprised of two parts – The Handbook, and The Theory. The Handbook is a guide for combining and interpreting experimental evidence to solve standard statistical problems. This section allows someone with a rudimentary knowledge in general statistics to apply the methods. The Theory provides the motivation, theory and results of simulation experiments to justify the methodology. This is a coherent introduction to the statistical concepts required to understand the authors’ thesis that evidence in a test statistic can often be calibrated when transformed to the right scale. |
| michael borenstein meta analysis: An Introduction to Systematic Reviews David Gough, Sandy Oliver, James Thomas, 2012-03-22 This timely, engaging book provides an overview of the nature, logic, diversity and process of undertaking systematic reviews as part of evidence informed decision making. A focused, accessible and technically up-to-date book, it covers the full breadth of approaches to reviews from statistical meta analysis to meta ethnography. It is ideal for anyone undertaking their own systematic review - providing all the necessary conceptual and technical background needed to make a good start on the process. The content is divided into five clear sections: • Approaches to reviewing • Getting started • Gathering and describing research • Appraising and synthesising data • Making use of reviews/models of research use. Easy to read and logically structured, this book is essential reading for anyone doing systematic reviews. David Gough is Professor of Evidence Informed Policy and Practice and Director of SSRU and its EPPI-Centre and Co-Editor of the journal Evidence & Policy. Sandy Oliver is Professor of Public Policy and Deputy Director of SSRU and its EPPI-Centre. James Thomas is Reader in Social Policy, Assistant Director of SSRU and Associate Direcctor of the EPPI-Centre. |
| michael borenstein meta analysis: Diagnostic Meta-Analysis Giuseppe Biondi-Zoccai, 2019-01-19 This book is the first exclusively devoted to the systematic synthesis of diagnostic test accuracy studies. It builds upon the major recent developments in reporting standards, search methods, and, in particular, statistical tools specifically devoted to diagnostic studies. In addition, it borrows extensively from the latest advances in systematic reviews and meta-analyses of intervention studies. After a section dedicated to methods for designing reviews, synthesizing evidence and appraising inconsistency in research, the application of these approaches is demonstrated in the context of case studies from various clinical disciplines. Diagnosis is central in medical decision-making, and in many other fields of human endeavor, such as education and psychology. The plurality of sources of evidence on diagnostic test accuracy poses a huge challenge for practitioners and researchers, as do the multiple dimensions of evidence validity, which include sensitivity, specificity, predictive values, and likelihood ratios. This book offers an invaluable resource for anyone aiming to improve decision-making processes in diagnosis, classification or risk prognostication, from epidemiologists to biostatisticians, radiologists, laboratory physicians and graduate students, as any physician interested in refining his methodological skills in clinical diagnosis. |
| michael borenstein meta analysis: Principles of Drug Addiction Treatment , 2011 This is a print on demand edition of a hard to find publication. Addresses addiction to a wide variety of drugs, incl. nicotine, alcohol, and illicit and prescription drugs. Contents: Principles of effective treatment; Why do drug-addicted persons keep using drugs?; What is Drug Addiction Treatment (DAT)?; How effective is it?; How long does DAT last?; How do we get more substance-abusing people into DAT?; What are the unique needs of women, and adolescents with substance use disorders?; Are there DAT for older adults, and people addicted to prescription drugs?; Is the use of medications like methadone and buprenorphine simply replacing one drug addiction with another?; Where do 12-step or self-help programs fit into DAT?; How does DAT help reduce the spread of HIV/AIDS, hepatitis C, and other infectious diseases? |
| michael borenstein meta analysis: Meta-Analytic Structural Equation Modelling Suzanne Jak, 2015-11-28 This book explains how to employ MASEM, the combination of meta-analysis (MA) and structural equation modelling (SEM). It shows how by using MASEM, a single model can be tested to explain the relationships between a set of variables in several studies. This book gives an introduction to MASEM, with a focus on the state of the art approach: the two stage approach of Cheung and Cheung & Chan. Both, the fixed and the random approach to MASEM are illustrated with two applications to real data. All steps that have to be taken to perform the analyses are discussed extensively. All data and syntax files are available online, so that readers can imitate all analyses. By using SEM for meta-analysis, this book shows how to benefit from all available information from all available studies, even if few or none of the studies report about all relationships that feature in the full model of interest. |
| michael borenstein meta analysis: The Oxford Handbook of the Five Factor Model Thomas A. Widiger, 2017-03-27 The Five Factor Model, which measures individual differences on extraversion, agreeableness, conscientiousness, emotional stability, and openness to experience, is arguably the most prominent dimensional model of general personality structure. In fact, there is now a considerable body of research supporting its construct validity and practical application in clinical, health, and organizational settings. Taking this research to the forefront, The Oxford Handbook of the Five Factor Model showcases the work of expert researchers in the field as they each offer important insight and perspective on all that is known about the Five Factor Model to date. By establishing the origins, foundation, and predominance of the Five Factor Model, this Handbook will focus on such areas as construct validity, diagnosis and assessment, personality neuroscience, and how the Five Factor Model operates in business and industry, animal personality, childhood temperament, and clinical utility. |
| michael borenstein meta analysis: Systematic Reviews in Educational Research Katja Buntins, Melissa Bond, Svenja Bedenlier, 2020-10-08 In this open access edited volume, international researchers of the field describe and discuss the systematic review method in its application to research in education. Alongside fundamental methodical considerations, reflections and practice examples are included and provide an introduction and overview on systematic reviews in education research.; Open Access With contributions from international experts First volume with a special focus on systematic reviews in educational research Contains practical examples Takes ethical considerations into account This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors. |
| michael borenstein meta analysis: Meta-analysis Ralf Schulze, 2004 Meta-analysis has become the standard method for summarizing research findings in many scientific fields. This book provides a comprehensive treatment and comparison of the statistical procedures available for meta-analysis with correlations as effect sizes. |
| michael borenstein meta analysis: Evidence Synthesis for Decision Making in Healthcare Nicky J. Welton, Alexander J. Sutton, Nicola Cooper, Keith R. Abrams, A. E. Ades, 2012-04-12 In the evaluation of healthcare, rigorous methods of quantitative assessment are necessary to establish interventions that are both effective and cost-effective. Usually a single study will not fully address these issues and it is desirable to synthesize evidence from multiple sources. This book aims to provide a practical guide to evidence synthesis for the purpose of decision making, starting with a simple single parameter model, where all studies estimate the same quantity (pairwise meta-analysis) and progressing to more complex multi-parameter structures (including meta-regression, mixed treatment comparisons, Markov models of disease progression, and epidemiology models). A comprehensive, coherent framework is adopted and estimated using Bayesian methods. Key features: A coherent approach to evidence synthesis from multiple sources. Focus is given to Bayesian methods for evidence synthesis that can be integrated within cost-effectiveness analyses in a probabilistic framework using Markov Chain Monte Carlo simulation. Provides methods to statistically combine evidence from a range of evidence structures. Emphasizes the importance of model critique and checking for evidence consistency. Presents numerous worked examples, exercises and solutions drawn from a variety of medical disciplines throughout the book. WinBUGS code is provided for all examples. Evidence Synthesis for Decision Making in Healthcare is intended for health economists, decision modelers, statisticians and others involved in evidence synthesis, health technology assessment, and economic evaluation of health technologies. |
| michael borenstein meta analysis: Meta-Analysis Mike W.-L. Cheung, 2015-05-06 Presents a novel approach to conducting meta-analysis using structural equation modeling. Structural equation modeling (SEM) and meta-analysis are two powerful statistical methods in the educational, social, behavioral, and medical sciences. They are often treated as two unrelated topics in the literature. This book presents a unified framework on analyzing meta-analytic data within the SEM framework, and illustrates how to conduct meta-analysis using the metaSEM package in the R statistical environment. Meta-Analysis: A Structural Equation Modeling Approach begins by introducing the importance of SEM and meta-analysis in answering research questions. Key ideas in meta-analysis and SEM are briefly reviewed, and various meta-analytic models are then introduced and linked to the SEM framework. Fixed-, random-, and mixed-effects models in univariate and multivariate meta-analyses, three-level meta-analysis, and meta-analytic structural equation modeling, are introduced. Advanced topics, such as using restricted maximum likelihood estimation method and handling missing covariates, are also covered. Readers will learn a single framework to apply both meta-analysis and SEM. Examples in R and in Mplus are included. This book will be a valuable resource for statistical and academic researchers and graduate students carrying out meta-analyses, and will also be useful to researchers and statisticians using SEM in biostatistics. Basic knowledge of either SEM or meta-analysis will be helpful in understanding the materials in this book. |
| michael borenstein meta analysis: Medical Statistics at a Glance Aviva Petrie, Caroline Sabin, 2019-09-30 Now in its fourth edition, Medical Statistics at a Glance is a concise and accessible introduction to this complex subject. It provides clear instruction on how to apply commonly used statistical procedures in an easy-to-read, comprehensive and relevant volume. This new edition continues to be the ideal introductory manual and reference guide to medical statistics, an invaluable companion for statistics lectures and a very useful revision aid. This new edition of Medical Statistics at a Glance: Offers guidance on the practical application of statistical methods in conducting research and presenting results Explains the underlying concepts of medical statistics and presents the key facts without being unduly mathematical Contains succinct self-contained chapters, each with one or more examples, many of them new, to illustrate the use of the methodology described in the chapter. Now provides templates for critical appraisal, checklists for the reporting of randomized controlled trials and observational studies and references to the EQUATOR guidelines for the presentation of study results for many other types of study Includes extensive cross-referencing, flowcharts to aid the choice of appropriate tests, learning objectives for each chapter, a glossary of terms and a glossary of annotated full computer output relevant to the examples in the text Provides cross-referencing to the multiple choice and structured questions in the companion Medical Statistics at a Glance Workbook Medical Statistics at a Glance is a must-have text for undergraduate and post-graduate medical students, medical researchers and biomedical and pharmaceutical professionals. |
| michael borenstein meta analysis: The Cult of Statistical Significance Stephen Thomas Ziliak, Deirdre Nansen McCloskey, 2008-02-19 How the most important statistical method used in many of the sciences doesn't pass the test for basic common sense |
| michael borenstein meta analysis: The Handbook of Research Synthesis and Meta-Analysis Harris Cooper, Larry V. Hedges, Jeffrey C. Valentine, 2019-06-14 Research synthesis is the practice of systematically distilling and integrating data from many studies in order to draw more reliable conclusions about a given research issue. When the first edition of The Handbook of Research Synthesis and Meta-Analysis was published in 1994, it quickly became the definitive reference for conducting meta-analyses in both the social and behavioral sciences. In the third edition, editors Harris Cooper, Larry Hedges, and Jeff Valentine present updated versions of classic chapters and add new sections that evaluate cutting-edge developments in the field. The Handbook of Research Synthesis and Meta-Analysis draws upon groundbreaking advances that have transformed research synthesis from a narrative craft into an important scientific process in its own right. The editors and leading scholars guide the reader through every stage of the research synthesis process—problem formulation, literature search and evaluation, statistical integration, and report preparation. The Handbook incorporates state-of-the-art techniques from all quantitative synthesis traditions and distills a vast literature to explain the most effective solutions to the problems of quantitative data integration. Among the statistical issues addressed are the synthesis of non-independent data sets, fixed and random effects methods, the performance of sensitivity analyses and model assessments, the development of machine-based abstract screening, the increased use of meta-regression and the problems of missing data. The Handbook also addresses the non-statistical aspects of research synthesis, including searching the literature and developing schemes for gathering information from study reports. Those engaged in research synthesis will find useful advice on how tables, graphs, and narration can foster communication of the results of research syntheses. The third edition of the Handbook provides comprehensive instruction in the skills necessary to conduct research syntheses and represents the premier text on research synthesis. Praise for the first edition: The Handbook is a comprehensive treatment of literature synthesis and provides practical advice for anyone deep in the throes of, just teetering on the brink of, or attempting to decipher a meta-analysis. Given the expanding application and importance of literature synthesis, understanding both its strengths and weaknesses is essential for its practitioners and consumers. This volume is a good beginning for those who wish to gain that understanding. —Chance Meta-analysis, as the statistical analysis of a large collection of results from individual studies is called, has now achieved a status of respectability in medicine. This respectability, when combined with the slight hint of mystique that sometimes surrounds meta-analysis, ensures that results of studies that use it are treated with the respect they deserve....The Handbook of Research Synthesis is one of the most important publications in this subject both as a definitive reference book and a practical manual.—British Medical Journal When the first edition of The Handbook of Research Synthesis was published in 1994, it quickly became the definitive reference for researchers conducting meta-analyses of existing research in both the social and biological sciences. In this fully revised second edition, editors Harris Cooper, Larry Hedges, and Jeff Valentine present updated versions of the Handbook's classic chapters, as well as entirely new sections reporting on the most recent, cutting-edge developments in the field. Research synthesis is the practice of systematically distilling and integrating data from a variety of sources in order to draw more reliable conclusions about a given question or topic. The Handbook of Research Synthesis and Meta-Analysis draws upon years of groundbreaking advances that have transformed research synthesis from a narrative craft into an important scientific process in its own right. Cooper, Hedges, and Valentine have assembled leading authorities in the field to guide the reader through every stage of the research synthesis process—problem formulation, literature search and evaluation, statistical integration, and report preparation. The Handbook of Research Synthesis and Meta-Analysis incorporates state-of-the-art techniques from all quantitative synthesis traditions. Distilling a vast technical literature and many informal sources, the Handbook provides a portfolio of the most effective solutions to the problems of quantitative data integration. Among the statistical issues addressed by the authors are the synthesis of non-independent data sets, fixed and random effects methods, the performance of sensitivity analyses and model assessments, and the problem of missing data. The Handbook of Research Synthesis and Meta-Analysis also provides a rich treatment of the non-statistical aspects of research synthesis. Topics include searching the literature, and developing schemes for gathering information from study reports. Those engaged in research synthesis will also find useful advice on how tables, graphs, and narration can be used to provide the most meaningful communication of the results of research synthesis. In addition, the editors address the potentials and limitations of research synthesis, and its future directions. The past decade has been a period of enormous growth in the field of research synthesis. The second edition Handbook thoroughly revises original chapters to assure that the volume remains the most authoritative source of information for researchers undertaking meta-analysis today. In response to the increasing use of research synthesis in the formation of public policy, the second edition includes a new chapter on both the strengths and limitations of research synthesis in policy debates |
| michael borenstein meta analysis: Applied Meta-Analysis with R Ding-Geng (Din) Chen, Karl E. Peace, 2013-05-03 In biostatistical research and courses, practitioners and students often lack a thorough understanding of how to apply statistical methods to synthesize biomedical and clinical trial data. Filling this knowledge gap, Applied Meta-Analysis with R shows how to implement statistical meta-analysis methods to real data using R. Drawing on their extensive research and teaching experiences, the authors provide detailed, step-by-step explanations of the implementation of meta-analysis methods using R. Each chapter gives examples of real studies compiled from the literature. After presenting the data and necessary background for understanding the applications, various methods for analyzing meta-data are introduced. The authors then develop analysis code using the appropriate R packages and functions. This systematic approach helps readers thoroughly understand the analysis methods and R implementation, enabling them to use R and the methods to analyze their own meta-data. Suitable as a graduate-level text for a meta-data analysis course, the book is also a valuable reference for practitioners and biostatisticians (even those with little or no experience in using R) in public health, medical research, governmental agencies, and the pharmaceutical industry. |
| michael borenstein meta analysis: JAMA Guide to Statistics and Methods Edward H. Livingston, Roger J. Lewis, 2019-11-29 Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. The world-renowned experts at JAMA® explain statistical analysis and the methods used in medical research Written in the language and style appropriate for clinicians and researchers, this new JAMA Guide to Statistics and Methods provides explanations and expert discussion of the statistical analytic approaches and methods used in the medical research reported in articles appearing in JAMA and the JAMA Network journals. This addition to the JAMAevidence® series is particularly timely and necessary because today’s physicians and other health care professionals must pursue lifelong learning to keep up with the ever-expanding universe of new medical science and evidence-based clinical information. Readers and users of research articles must have a firm grasp of the myriad new statistical, analytic, and methodologic approaches used in contemporary medical studies. To provide concrete examples, the explanations in the book link to research articles that incorporate the specific statistical test or methodological approach being discussed. |
| michael borenstein meta analysis: Systematic Reviews in Health Care George Davey Smith, Douglas G. Altman, Matthias Egger, 2008 The second edition of this best-selling book has been thoroughly revised and expanded to reflect the significant changes and advances made in systematic reviewing. New features include discussion on the rationale, meta-analyses of prognostic and diagnostic studies and software, and the use of systematic reviews in practice. |
| michael borenstein meta analysis: Weight Bias Kelly D. Brownell, Rebecca M. Puhl, Marlene B. Schwartz, Leslie Rudd, 2005-08-24 Discrimination based on body shape and size remains commonplace in today's society. This important volume explores the nature, causes, and consequences of weight bias and presents a range of approaches to combat it. Leading psychologists, health professionals, attorneys, and advocates cover such critical topics as the barriers facing obese adults and children in health care, work, and school settings; how to conceptualize and measure weight-related stigmatization; theories on how stigma develops; the impact on self-esteem and health, quite apart from the physiological effects of obesity; and strategies for reducing prejudice and bringing about systemic change. |
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