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| kvols brockman death: The Peptidergic Neuron B. Krisch, 2012-12-06 Neuropeptides rank among the phylogenetically oldest interneuronal signal substances. In the concept of neuro-secretion they were identified as neurohormones by which - via the blood - the brain regulates peripheral functions. It is now evident that the neuropeptides act as neurotransmitters/-modulators, as (neuro-)hormones, and paracrine or autocrine signal substances in diverse parts of the body. This book reviews, in several comprehensive articles written by distinguished specialists, the state of the art in the field of neuropeptides and peptidergic neurons. Special topics concern molecular aspects of processing, release and degradation of neuropeptides, receptors and signal transduction, comparative and behavioural aspects, and immunoregulatory effects of neuropeptides and their involvement on pathology of the central nervous system. |
| kvols brockman death: Clinical Endocrinology of Dogs and Cats A. Rijnberk, 2012-12-06 Clinical endocrinology is a fascinating field requiring the challenging combination of broad pathophysiological interest and specific expertise in the field of endocrinology, thereby occupying a common ground between biochemistry, physiology and clinical medicine. In the majority of cases the clinician's notion of the presence of an endocrine disease is largely based upon pattern recognition, in which physical changes play an important role. Therefore many color illustrations have been included throughout the text. In addition there are many full color graphs and illustrations of diagnostic imaging and pathology. With over 350 illustrations the book represents a richly illustrated text on the diseases of endocrine glands. For each gland there is an introductory section on the relevant morphology and physiology, followed by descriptions of the disorders of the gland. When endocrine diseases are quite different in dogs and cats, separate descriptions are given for these species. Protocols for function tests and emergency treatments are presented in the last chapters. Consequently the book provides the user with both comprehensive descriptions and quick references. The book has been written by leading clinicians in the field, with contributions from two biochemists, a radiologist and pathologist. As such a valuable textbook for veterinary students and practitioners has been compiled to fulfil the need for an up-to-date and complete book on endocrine diseases of dogs and cats. |
| kvols brockman death: The NPY Family of Peptides in Immune Disorders, Inflammation, Angiogenesis, and Cancer Zofia Zukowska, Giora Z. Feuerstein, 2006-01-17 Recent research indicates that the immune system and inflammatory reactions are governed and regulated by powerful neuronal mediators derived from the central and peripheral nervous system. The NPY family of peptides is a diverse group of neuropeptides that acts via multiple receptors, Y1-Y5, which are widespread not only in neurons but also in a variety of non-neural and immune cells. These peptides have been known as important regulators of many essential systems, such as blood pressure and cardiac function, food consumption and energy homeostasis. However, in recent years, they have also become recognized for their role as potent modulators of cell growth and immune functions with broad implications in chronic inflammatory diseases, cancer and angiogenesis. In this book, experts in the field analyze recent evidence supporting the role of NPY family of peptides in regulation of the immune/inflammatory system with special reference to its medical and therapeutic implications. |
| kvols brockman death: Phosphoinositides I: Enzymes of Synthesis and Degradation Tamas Balla, Matthias Wymann, John D. York, 2012-03-14 Phosphoinositides play a major role in cellular signaling and membrane organization. During the last three decades we have learned that enzymes turning over phosphoinositides control vital physiological processes and are involved in the initiation and progression of cancer, inflammation, neurodegenerative, cardiovascular, metabolic disease and more. In two volumes, this book elucidates the crucial mechanisms that control the dynamics of phosphoinositide conversion. Starting out from phosphatidylinositol, a chain of lipid kinases collaborates to generate the oncogenic lipid phosphatidylinositol(3,4,5)-trisphosphate. For every phosphate group added, there are specific lipid kinases – and phosphatases to remove it. Additionally, phospholipases can cleave off the inositol head group and generate poly-phosphoinositols, which act as soluble signals in the cytosol. Volume I untangles the web of these enzymes and their products, and relates them to function in health and disease. Phosphoinositide 3-kinases and 3-phosphatases have received a special focus in volume I, and recent therapeutic developments in human disease are presented along with a historical perspective illustrating the impressive progress in the field. |
| kvols brockman death: Lymphoma Anas Younes, Bertrand Coiffier, 2013-05-17 Recently, understanding the molecular pathogenesis of malignant lymphomas has led to improvement in the diagnostic precision and to the identification of a variety of molecular therapeutic targets. In addition, new drugs have been approved in the US and Europe, resulting in changes in the standard of care of several types of lymphoid malignancies. Comprehensive in scope and developed by a team of internationally renowned authors, Lymphoma: Diagnosis and Treatment provides a timely update on the most important advances in the biology, diagnosis, and therapy of lymphomas. As part of the Current Clinical Oncology series, Lymphoma: Diagnosis and Treatment will be of value to medical oncologists, hematologists, radiation oncologists, and all physicians involved in the care of patients with lymphoid malignancies. |
| kvols brockman death: Molecular Mechanisms of Parasite Invasion Barbara A. Burleigh, Dominique Soldati, 2008-12-05 All of the parasitic organisms highlighted in this new book represent medically important human pathogens that contribute significantly to the global burden of disease. As such there is intense interest in understanding the molecular basis of infection by these pathogens—not only with regard to their clinical relevance but also the fascinating biology they reveal. For most of the parasites discussed here the ability to penetrate biological barriers and/or to establish intracellular residence is critical to survival of the pathogen in the mammalian hosts. For other parasites, a tissue invasive phenotype is a key virulence determinant. In the ensuing 18 chapters, select members of this diverse set of protozoan parasites, as well as some examples of the extremely reduced fungal parasites classified as Microsporidia, are discussed within the context of the fascinating molecular strategies employed by these organisms to migrate across biological barriers and to establish residence within target host cells. |
| kvols brockman death: Creatine and Creatine Kinase in Health and Disease Gajja S. Salomons, Markus Wyss, 2007-10-16 Although creatine was discovered already in the 1830s, it is only in recent years that its crucial role for human health and general well-being has been increasingly realized and appreciated. A number of beneficial health effects have been ascribed to oral creatine supplementation, such as neuroprotective, ergogenic, anti-diabetic, anti-inflammatory, antiviral, or antitumor effects. Creatine may even improve memory and intelligence. In the present book, emphasis is placed on the intricate interplay between creatine and creatine kinase function on one hand, and proper brain function, neurodegenerative disease and/or neuroprotection on the other hand. The book also elaborates on the recently identified inborn errors of creatine biosynthesis and transport, the so-called cerebral creatine deficiency syndromes. The clinical hallmarks of these disorders are mental retardation, epilepsy, autistic-like behaviour, and speech and language delay. In addition, the muscle growth- and strength-promoting effects, the pharmacokinetics and the safety of oral creatine supplementation are discussed. Finally, the present book outlines the emerging systems biology approaches for understanding the pleiotropic effects of creatine and creatine kinase, and hypothesizes on the most promising and influential future avenues of research towards creatine-based nutritional strategies for the prevention of neurological disease, and for improving the quality of life in general. |
| kvols brockman death: Enzyme-Catalyzed Electron and Radical Transfer Andreas Holzenburg, Nigel S. Scrutton, 2000-12-31 Dramatic advances have been made in recent years in the field of redox enzymology which has resulted in an increase of research activities. This volume will cover the recent milestone developments in this field by leading experts, uniting theory and experiment, and selecting contributions to illustrate important aspects of the mechanisms of electron and radical transfer in proteins. Features: A demonstration of the key principles controlling biological redox reactions; Experimental studies of `simple' soluble systems in various enzyme familiies to illustrate concepts in the control of electron transfer reactions; Detail of advances made in membrane electron transfer through structural descriptions of key membrane-embedded proteins; Appeal to those interested in the design and use of redox enzymes, from academics to industrialists. |
| kvols brockman death: Chromatin and Disease Tapas K. Kundu, Dipak Dasgupta, 2007-05-04 This book includes a collection of articles with the broad theme of disease connection to chromatin structure and function. It elaborates on the molecular pharmacology of the drugs targeting chromatin structure and its components. The book contains up-to-date information about the chromatin structure and chromatin related diseases and drug functions. This work is the first endeavor to present different aspects encompassing the above theme. |
| kvols brockman death: Calcium Signalling and Disease Ernesto Carafoli, Marisa Brini, 2010-11-20 Authors highlight several promising discoveries in the field of calcium signaling that provide new information about both genetic and acquired pathologies. Their discussions will give you new insights into the underlying causes of congenital and acquired diseases and point the way to new, even more promising research and therapies. |
| kvols brockman death: Adlerian Psychotherapy Jon Carlson, Matt Englar-Carlson, 2017 This book provides an introduction and overview to Alfred Adler's person-centered approach to psychotherapy. In Adler's view, all behavior has social meaning, and the socio-cultural context of a person's life is a driving influence on their mental health and life experiences. |
| kvols brockman death: Contact Counseling Len Sperry, Lee R. Hess, 1974 |
| kvols brockman death: Working with Dreams Montague Ullman, Nan Zimmerman, 2017-09-07 Originally published in 1979, this is a dream book with an outstanding difference: it takes the interpretation of dreams out of the realm of the professionals and gives it to the ultimate expert – the dreamer. Working with Dreams stresses the uniqueness of every dream and dreamer. With anecdotes and examples from their own dream groups, the authors show how to deal with the intimacy and honesty of a dream; how to explore its meanings without distorting them; how to let a dream tell us about ourselves and add to our understanding. Dr Ullman and Mrs Zimmerman start with the question of what is in a dream – what is real and what is symbolic? – and then go on to explain what happens during sleep and the way a dream develops. They cover remembering and recording dreams and dealing with the imagery of dreams. They illustrate the many predicaments that dreams depict, the self-deceptions we practice in relation to our dreams, and then show how dream groups – whether a family or a group of strangers – can work together to uncover the meaning of dreams. And they enrich their book by discussing everything from the history of dreams to the possibilities of dreams across space and time. The result is a storehouse of information about the world of dreams. |
| kvols brockman death: The Psychology of Courage Julia Yang, Alan Milliren, 2009-07-29 Courage refers to the willingness for risk taking and to move ahead in the presence of difficulties. The purpose of this book is to present courage as the main foundation of understanding and training for mental health in the three life task areas described by Adler: Work, Love, and Friendship. It explores the meaning of each life task and problems of fear, compensation, or evasion, as well as Adlerian insight on socially useful attitudes of approaching the task under discussion. Socratic dialog boxes are included throughout each chapter to encourage the interactivity between the text and readers’ thought processes. Also included is a set of twenty-two helping tools that were creatively designed for self-exercise or to be used to help others uncover or acquire courage. For those in the helping professions, this text will be a unique and valuable handbook for not only working with and helping their clients, but also for their own personal development. |
| kvols brockman death: The Lexicon of Adlerian Psychology Jane Griffith, Robert L. Powers, 2007 The Adlerian Lexicon features 106 inclusive entries of terms (one entry per page) associated with the Individual Psychology of Alfred Adler, with a foreword by Guy J. Masaster, Ph.D., University of Texas at Austin, president of the International Association of Individual Psychology; an introduction to Adler; an extensive bibliography of Adlerian materials; and an index. Adler, who with Freud and Jung was one of the founders of modern psychology, chose the term Individual Psychology to represent his emphasis on the holism of the individual (individual = that which cannot be divided), as distinguished from a consideration of the individual in terms of part processes. The Adlerian Lexicon has no competitor in the English language. It serves as the authoritative reference work for practitioners, students, and scholars of modern psychiatry and psychology. Originally published in 1984, the present text is the second edition, revised and expanded. |
| kvols brockman death: Concepts of Personality Joseph M. Wepman, Ralph W. Heine, 2008-09-01 The psychologist who pursues an interest in personality is constantly faced by a dilemma. He seeks to investigate what is to him the most intriguing and interesting subject--the multifaceted operations of man in his natural environment. The predicament lies in the discrepancy between the complexity and richness of man's subjective experience, and the pallid analog of these experiences the psychologist is able to study effectively with the research procedures available to him. In Concepts of Personality Joseph M. Wepman and Ralph W. Heine offer a comprehensive survey of classical and contemporary personality theory, including a wide array of examples of these two trends. If the psychologist holds to the premises of strict objectivity through controlled observations, he finds himself driven to the periphery of the very problem he seeks to understand. This is a place where the reliability of measurement and the validity and predictability of his instruments can often be specified, but only at the cost of abandoning the goal of useful generality or of application to the individual in his ordinary life circumstances. Concepts of Personality, unlike most books on the subject, is not limited to broad, general theories. It includes chapters on basic processes--learning, perception, genetics, and drive theory; on the major analytical approaches of psychology and psychiatry; on anthropological and sociological contributions; and on the problems of measurement and assessment. Each chapter is by an authority on the point of view expressed. The editors' introduction, itself a major essay on the complex and divergent patterns and themes of contemporary views of personality, carefully leads the reader through the information at hand. The book as a whole constitutes an encyclopedic summary of the state of the science. Joseph M. Wepman was professor of psychology and surgery and chairman of the Interdepartmental Clinical and Counseling Psychology Training Program of the University of Chicago. He is the author of Recovering from Aphasia and Aphasia and the Family. Ralph W. Heine was professor of psychiatry and psychology and chief clinical psychologist in the department of psychiatry at the University of Chicago. He is the author of The Student Physician as Psychotherapist and Psychotherapy. |
| kvols brockman death: Clinical Endocrinology of Companion Animals Jacquie Rand, Ellen Behrend, Danielle Gunn-Moore, Michelle Campbell-Ward, 2012-11-13 Clinical Endocrinology of Companion Animals offers fast access to clinically relevant information on managing the patient with endocrine disease. Written by leading experts in veterinary endocrinology, each chapter takes the same structure to aid in the rapid retrieval of information, offering information on pathogenesis, signalment, clinical signs, diagnosis, differential diagnosis, treatment, prognosis, and prevention for a broad list of endocrine disorders. Chapters begin with brief summaries for quick reference, then delve into greater detail. With complete coverage of the most common endocrine diseases, the book includes chapters on conditions in dogs, cats, horses, ferrets, reptiles, and other species. Clinical Endocrinology of Companion Animals is a highly practical resource for any veterinarian treating these common diseases. |
| kvols brockman death: Encyclopedia of Psychology, 4 Volume Set Raymond J. Corsini, 1994-03 Includes entries on such topics as psychoanalysis, assertiveness training, neurotransmitters, and small-sample statistics. |
| kvols brockman death: Physiology of Domestic Animals Øystein V. Sjaastad, Sjaastad V., Hove Knut, Olav Sand, 2004 |
| kvols brockman death: Operational Theories of Personality Arthur Burton, 1974 |
| kvols brockman death: Character Education in Adolescence Rudolf Allers, 1940 |
| kvols brockman death: The Psychology of Hope Ezra Stotland, 1969 A dynamic and systematic new approach to experimental and clinical psychology. The author uses a wide range of data from a vast number of experimental and clinical studies to demonstrate how the different levels of expectation and goal achievement can be studied objectively. Building from simple to highly complex schemas, he conceptualizes hope and its counterpart, hopelessness, as both necessary and vital to motivation, action and non-action (lethargy) in animal as well as human behaviour. |
| kvols brockman death: Methods of Group Psychotherapy Raymond J. Corsini, 1957 |
| kvols brockman death: Manual for Life Style Assessment Bernard H. Shulman, Harold H. Mosak, 1988 First published in 1988. Routledge is an imprint of Taylor & Francis, an informa company. |
| kvols brockman death: The Crisis in Psychiatry and Religion Orval Hobart Mowrer, 1961 |
| kvols brockman death: Catharsis in Psychotherapy Michael P. Nichols, Melvin Zax, 1977 |
| kvols brockman death: Child and Adult Before God André Godin, 1965 |
| kvols brockman death: Parenting Young Children Gary McKay, Don C. Dinkmeyer, James S. Dinkmeyer, 2008 Offers helpful strategies for parents of children under six. |
| kvols brockman death: Current Personality Theories Raymond J. Corsini, 1977 |
| kvols brockman death: Critical Incidents in Psychotherapy Stanley W. Standal, Raymond J. Corsini, 1959 |
| kvols brockman death: Pathos of Power Kenneth Bancroft Clark, 1974 Discusses the ability of psychotechnology to control the fragility and pathos of the ego, which can create and validate humanity while also rationalizing cruelties and inhumanity. The negative, animalistic characteristics of man must be subordinated to the positive values of love and empathy without sacrificing creativity or selective capacities. It is proposed that a program of direct biochemical intervention be implemented to control negativistic tendencies. Ultimately, world leaders who have the nuclear power to determine the fate of humanity should be given the earliest perfected form of appropriate drugs. This requirement would control the barbaric use of power and insure that survival of the human species is not sacrificed to the personal ego pathos of powerful individuals. |
| kvols brockman death: The History of Psychiatry Franz Alexander (d), Sheldon T. Selesnick, 1966 |
| kvols brockman death: Earliest Childhood Memories Arnold Bruhn, 1990-11-26 How is a sense of self formed from memory? It is difficult to conceptualize a psychology of the self without memory serving as the foundation. Earliest Childhood Memories provides a structure and a theory by which this question can be addressed. Cognitive-Perceptual Theory is the only personality theory grounded on autobiographical memory. In addition, Cognitive-Perceptual Theory addresses how personal growth and personality affect memory organization. When a personality change occurs, early memories change in a parallel manner to reflect the current world view (realign). The Early Memories Procedure (EMP), the first procedure to assess autobiographical memory, consists of five spontaneous early memories, a particularly clear or important memory (lifetime), fifteen directed memories of various types, several rating scales, and open-ended questions. The procedure assesses all major clinically relevant areas of autobiographical memory. The first non-edited book on early memories addressed to professionals, this volume will be of interest to analysts, clinical psychologists, psychiatrists, social workers, school psychologists, and counselors. |
| kvols brockman death: The Parent's Handbook Don C. Dinkmeyer, Gary D. Mckay, 1997 The STEP (Systematic Training for Effective Parenting) program has taught over two million parents more effective parenting techniques, encouraging mutual respect between parent and child, cooperation, responsibility, and self-reliance. The Parent's Handbook shows parents the best way to raise responsible children who will grow into responsible adults. Illustrations & charts. Size C. 136 pp. 30,000 print. |
| kvols brockman death: Family Constellation Walter Toman, 1969 |
| kvols brockman death: American Therapy Jonathan Engel, 2011-01 Begins with Sigmund Freud, who in 1910 brought his nascent movement over from Europe. His techniques laid the groundwork for therapy as we know it today. Engel paints a broad picture of the mental health care landscape in America. He looks at the groups that deliver what is understood as psychotherapy: the efforts of social workers, priests, and pastoral counselors, as well as self-help gurus and support groups like Alcoholics Anonymous. A change in psychotherapy began in the 1970s with the advent of cognitive-behavioral therapy, which brought us into the age of tailored therapeutic interventions. żThere is something uniquely American about the way we have taken to therapy as a form of health care and as a kind of self-improvement.ż |
| kvols brockman death: Boundaries of the Soul June K. Singer, 1973 |
| kvols brockman death: Freud and His Followers Paul Foazen, 1974 A Meridian book. Includes bibliographical references and index. |
| kvols brockman death: Systems and Theories of Psychology James P. Chaplin, T. S. Krawiec, 1970 |
| kvols brockman death: The Natural Superiority of Women Ashley Montagu, 1968 |
Filiano Lab – Investigating Neuro-Immune Communication in ...
Investigating Neuro-Immune Communication in Health and Disease
Filiano Lab | Duke Department of Neurosurgery
Our lab is interested in understanding the complex interactions between the immune system and nervous system with the intent to uncover novel therapeutic targets to combat diseases such …
Anthony J Filiano | Duke Marcus Center for Cellular Cures
Our lab is interested in understanding the complex interactions between the immune system and nervous system with the intent to uncover novel therapeutic targets to combat diseases such …
Anthony J Filiano | Duke Institute for Brain Sciences
Our lab is interested in understanding the complex interactions between the immune system and nervous system with the intent to uncover novel therapeutic targets to combat diseases such …
Anthony J Filiano | Duke Department of Neurosurgery
Our lab is interested in understanding the complex interactions between the immune system and nervous system with the intent to uncover novel therapeutic targets to combat diseases such …
Anthony Filiano - Google Scholar
How and why do T cells and their derived cytokines affect the injured and healthy brain? AJ Filiano, LH Martens, AH Young, BA Warmus, P Zhou, G Diaz-Ramirez, ... ME Ward, A …
Projects – Filiano Lab
Our lab is a neuroimmunology lab, primarily investigating mechanisms of the interplay between the immune system and central nervous system in health and disease. Ongoing projects focus …
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