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| ketamine washington post: Beautiful Things Hunter Biden, 2021-04-06 Hunter Biden recounts his descent into substance abuse and his tortuous path to sobriety. The story ends with where Hunter is today |
| ketamine washington post: The Writer's Crusade Tom Roston, 2021-11-09 The story of Kurt Vonnegut and Slaughterhouse-Five, an enduring masterpiece on trauma and memory Kurt Vonnegut was twenty years old when he enlisted in the United States Army. Less than two years later, he was captured by the Germans in the single deadliest US engagement of the war, the Battle of the Bulge. He was taken to a POW camp, then transferred to a work camp near Dresden, and held in a slaughterhouse called Schlachthof Fünf where he survived the horrific firebombing that killed thousands and destroyed the city. To the millions of fans of Vonnegut’s great novel Slaughterhouse-Five, these details are familiar. They’re told by the book’s author/narrator, and experienced by his enduring character Billy Pilgrim, a war veteran who “has come unstuck in time.” Writing during the tumultuous days of the Vietnam conflict, with the novel, Vonnegut had, after more than two decades of struggle, taken trauma and created a work of art, one that still resonates today. In The Writer’s Crusade, author Tom Roston examines the connection between Vonnegut’s life and Slaughterhouse-Five. Did Vonnegut suffer from Post-Traumatic Stress Disorder? Did Billy Pilgrim? Roston probes Vonnegut’s work, his personal history, and discarded drafts of the novel, as well as original interviews with the writer’s family, friends, scholars, psychologists, and other novelists including Karl Marlantes, Kevin Powers, and Tim O’Brien. The Writer’s Crusade is a literary and biographical journey that asks fundamental questions about trauma, creativity, and the power of storytelling. |
| ketamine washington post: The Silent Patient Alex Michaelides, 2019-02-05 **THE INSTANT #1 NEW YORK TIMES BESTSELLER** An unforgettable—and Hollywood-bound—new thriller... A mix of Hitchcockian suspense, Agatha Christie plotting, and Greek tragedy. —Entertainment Weekly The Silent Patient is a shocking psychological thriller of a woman’s act of violence against her husband—and of the therapist obsessed with uncovering her motive. Alicia Berenson’s life is seemingly perfect. A famous painter married to an in-demand fashion photographer, she lives in a grand house with big windows overlooking a park in one of London’s most desirable areas. One evening her husband Gabriel returns home late from a fashion shoot, and Alicia shoots him five times in the face, and then never speaks another word. Alicia’s refusal to talk, or give any kind of explanation, turns a domestic tragedy into something far grander, a mystery that captures the public imagination and casts Alicia into notoriety. The price of her art skyrockets, and she, the silent patient, is hidden away from the tabloids and spotlight at the Grove, a secure forensic unit in North London. Theo Faber is a criminal psychotherapist who has waited a long time for the opportunity to work with Alicia. His determination to get her to talk and unravel the mystery of why she shot her husband takes him down a twisting path into his own motivations—a search for the truth that threatens to consume him.... |
| ketamine washington post: Ketamine for Treatment-Resistant Depression Sanjay J. Mathew, Carlos A. Zarate, Jr., 2018-07-07 This book brings together an international group of clinicians and researchers from a broad swath of inter-related disciplines to offer the most up-to-date information about clinical and preclinical research into ketamine and second-generation “ketamine-like” fast-acting antidepressants. Currently available antidepressant medications act through monoaminergic systems, are ineffective for many individuals suffering from depression, and are associated with a delayed onset of peak efficacy of several months. The unexpected emergence of ketamine, an anesthetic N-methyl-D-aspartate (NMDA) receptor antagonist, as a rapid-acting antidepressant has reinvigorated CNS drug discovery research and catalyzed investigation in patient populations historically ignored in antidepressant drug development programs, particularly treatment-resistant patients and those with suicidality. Recent industry and academic research efforts have coalesced to explore NMDA receptor and glutamatergic molecular targets that lack ketamine’s psychotomimetic side effects and abuse liability but retain its rapid onset of efficacy. However, many fundamental questions remain regarding the neurobiological mechanisms underlying ketamine’s rapid antidepressant effects and the puzzling persistence of benefits observed in some patients following a single dose. This book examines how insights from these studies are forging new conceptual models of the neurobiology of stress-related affective, anxiety, and addictive disorders and the nature of treatment resistance. It also discusses how ketamine’s rapid antidepressant effects provide a scientific platform to facilitate innovation in clinical trial designs pertaining to patient selection, choice of control group, outcome measures, and dose-optimization. This book brings together data and insights from this rapidly expanding and extraordinarily promising field of study. Readers will be able to extract integrated themes and useful insights from the material contained in these diverse chapters and appreciate the paradigm-shifting contributions of ketamine to modern psychiatry and clinical neuroscience research. |
| ketamine washington post: The Ketamine Handbook Janelle Lassalle, 2023-07-11 Once known as a horse tranquilizer drug or Special K, today, ketamine is being hailed as a new wonder drug for treatment-resistant conditions like depression and chronic pain. So what exactly is this mysterious drug, anyway? How does it work, and does it live up to the hype? Now, thanks to The Ketamine Handbook, you can understand exactly what ketamine is and how it could make an impact in your life. Written with easy, simple-to-understand terminology, this book aims to answer important questions like: What's the history of ketamine? What is ketamine-assiated psychotherapy [KAP]? How is ketamins different from psilocybin, LSD, cannabis and THC, and other psychadelics? What are the different types and forms of ketamine? Can KAP address conditions like anxiety, depression, chronic pain, PTSD, and trauma? What is the latest research, and what are the potential future applications? The answers, studies, and more are all included in this beginner-friendly guidebook that will help you navigate the potential benefits and applications of ketamine. |
| ketamine washington post: Zero Fail Carol Leonnig, 2021-05-18 NEW YORK TIMES BESTSELLER • The first definitive account of the rise and fall of the Secret Service, from the Kennedy assassination to the alarming lapses of the Obama and Trump years—from Pulitzer Prize–winning journalist Carol Leonnig “This book is a wake-up call, and a valuable study of a critically important agency.”—The New York Times A WASHINGTON POST BEST BOOK OF THE YEAR Carol Leonnig reported on the Secret Service for nearly a decade, bringing to light the secrets, scandals, and shortcomings that plague the agency today—from a toxic workplace culture to dangerously outdated equipment to the deep resentment within the ranks at key agency leaders, who put protecting the agency’s once-hallowed image before fixing its flaws. The Secret Service was born in 1865, in the wake of the assassination of Abraham Lincoln, but its story begins in earnest in 1963, with the death of John F. Kennedy. Shocked into reform by its failure to protect the president on that fateful day in Dallas, this once-sleepy agency was radically transformed into an elite, highly trained unit that would redeem itself several times, most famously in 1981 by thwarting an assassination attempt against Ronald Reagan. But by Barack Obama’s presidency, the once-proud Secret Service was running on fumes and beset by mismanagement and mistakes in judgement: break-ins at the White House, an armed gunman firing into the windows of the residence while confused agents stood by, and a massive prostitution scandal among agents in Cartagena, to name just a few. With Donald Trump’s arrival, a series of promised reforms were cast aside, as a president disdainful of public service instead abused the Secret Service to rack up political and personal gains. To explore these problems in the ranks, Leonnig interviewed dozens of current and former agents, government officials, and whistleblowers who put their jobs on the line to speak out about a hobbled agency that is in desperate need of reform. |
| ketamine washington post: The Revolutionary Ketamine Johnathan Edwards, 2023-07-11 This isn't a new drug, but it's now being used to treat depression with amazing results. What exactly is it? Is it safe? Is it right for you or your loved one? Suicide captures everyone’s attention. Suicide is a tragedy usually preceded by plenty of pain. About 1 million go through with the act each year. Imagine if your loved one is determined to end their life, and you could get them help. After reading Revolutionary Ketamine, you will understand: Suicide’s devastating cost to society and how to prevent it Why children and adolescents are committing suicide How ketamine stops suicide in its tracks Suicide is the stuff of other people’s nightmares until it happens to someone you love. Time simply stops, leaving you wondering what could have been done. Suicidal ideations hijack our brains, telling us to end our lives prematurely. What if we could remove this hijacking device? Ketamine is the one drug we have today that can safely halt suicidal ideations, yet most have never heard of it. To those who say more studies are needed to know if ketamine helps with suicidal ideations and depression, I offer you this admonition before trying the drug. If you are suffering from depression and suicidal ideations, the risk versus reward is clearly in favor of using ketamine now. Don’t wait. Dr. Edwards, the author of Revolutionary Ketamine, is committed to helping those who need never become statistics at all and will equip you with the tools to save your loved one’s life, or possibly your own. |
| ketamine washington post: All In Billie Jean King, Johnette Howard, Maryanne Vollers, 2021-08-17 NEW YORK TIMES BEST SELLER • An inspiring and intimate self-portrait of the champion of equality that encompasses her brilliant tennis career, unwavering activism, and an ongoing commitment to fairness and social justice. “A story about the personal strength, immense growth, and undeniable greatness of one woman who fearlessly stood up to a culture trying to break her down.”—Serena Williams In this spirited account, Billie Jean King details her life's journey to find her true self. She recounts her groundbreaking tennis career—six years as the top-ranked woman in the world, twenty Wimbledon championships, thirty-nine grand-slam titles, and her watershed defeat of Bobby Riggs in the famous Battle of the Sexes. She poignantly recalls the cultural backdrop of those years and the profound impact on her worldview from the women's movement, the assassinations and anti-war protests of the 1960s, the civil rights movement, and, eventually, the LGBTQ+ rights movement. She describes the myriad challenges she's hurdled—entrenched sexism, an eating disorder, near financial peril after being outed—on her path to publicly and unequivocally acknowledging her sexual identity at the age of fifty-one. She talks about how her life today remains one of indefatigable service. She offers insights and advice on leadership, business, activism, sports, politics, marriage equality, parenting, sexuality, and love. And she shows how living honestly and openly has had a transformative effect on her relationships and happiness. Hers is the story of a pathbreaking feminist, a world-class athlete, and an indomitable spirit whose impact has transcended even her spectacular achievements in sports. |
| ketamine washington post: Our Love Affair with Drugs Jerrold Winter, 2020 In Our Love Affair with Drugs, Jerrold Winter provides a nontechnical, accessible account of the effects of psychoactive drugs in America. |
| ketamine washington post: Compounded Topical Pain Creams National Academies of Sciences, Engineering, and Medicine, Health and Medicine Division, Board on Health Sciences Policy, Committee on the Assessment of the Available Scientific Data Regarding the Safety and Effectiveness of Ingredients Used in Compounded Topical Pain Creams, 2020-07-21 Pain is both a symptom and a disease. It manifests in multiple forms and its treatment is complex. Physical, social, economic, and emotional consequences of pain can impair an individual's overall health, well-being, productivity, and relationships in myriad ways. The impact of pain at a population level is vast and, while estimates differ, the Centers for Disease Control and Prevention reported that 50 million U.S. adults are living in pain. In terms of pain's global impact, estimates suggest the problem affects approximately 1 in 5 adults across the world, with nearly 1 in 10 adults newly diagnosed with chronic pain each year. In recent years, the issues surrounding the complexity of pain management have contributed to increased demand for alternative strategies for treating pain. One such strategy is to expand use of topical pain medicationsâ€medications applied to intact skin. This nonoral route of administration for pain medication has the potential benefit, in theory, of local activity and fewer systemic side effects. Compounding is an age-old pharmaceutical practice of combining, mixing, or adjusting ingredients to create a tailored medication to meet the needs of a patient. The aim of compounding, historically, has been to provide patients with access to therapeutic alternatives that are safe and effective, especially for people with clinical needs that cannot otherwise be met by commercially available FDA-approved drugs. Compounded Topical Pain Creams explores issues regarding the safety and effectiveness of the ingredients in these pain creams. This report analyzes the available scientific data relating to the ingredients used in compounded topical pain creams and offers recommendations regarding the treatment of patients. |
| ketamine washington post: All the Worst Humans Phil Elwood, 2024-06-25 A New York Times Notable Book A New York Times Editors' Choice A New York Post Best Book of the Year An Amazon Best Biography/Memoir A rollicking, unexpectedly affecting story. . . It’s going to be one of the big, buzzy Beltway books of the year. —Politico A bridge-burning, riotous memoir by a top PR operative in Washington who exposes the secrets of the $129-billion industry that controls so much of what we see and hear in the media—from a man who used to pull the strings, and who is now pulling back the curtain. After nearly two decades in the Washington PR business, Elwood wants to come clean, by exposing the dark underbelly of the very industry that’s made him so successful. The first step is revealing exactly what he’s been up to for the past twenty years—and it isn’t pretty. Elwood has worked for a murderer’s row of questionable clients, including Gaddafi, Assad, and the government of Qatar. In All the Worst Humans, Elwood unveils how the PR business works, and how the truth gets made, spun, and sold to the public—not shying away from the gritty details of his unlikely career. This is a piercing look into the corridors of money, power, politics, and control, all told in Elwood’s disarmingly funny and entertaining voice. He recounts a four-day Las Vegas bacchanal with a dictator’s son, plotting communications strategies against a terrorist organization in Western Africa, and helping to land a Middle Eastern dictator’s wife a glowing profile in Vogue on the same time the Arab Spring broke out. And he reveals all his slippery tricks for seducing journalists in order to create chaos and ultimately cover for politicians, dictators, and spies—the industry-secret tactics that led to his rise as a political PR pro. Along the way, Phil walks the halls of the Capitol, rides in armored cars through Abuja, and watches his client lose his annual income at the roulette table. But as he moved up the ranks, he felt worse and worse about the sleaziness of it all—until Elwood receives a shocking wake-up call from the FBI. This risky game nearly cost Elwood his life and his freedom. Seeing the light, Elwood decides to change his ways, and his clients, and to tell the full truth about who is the worst human. |
| ketamine washington post: Pain Management and the Opioid Epidemic National Academies of Sciences, Engineering, and Medicine, Health and Medicine Division, Board on Health Sciences Policy, Committee on Pain Management and Regulatory Strategies to Address Prescription Opioid Abuse, 2017-10-28 Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring. |
| ketamine washington post: Student Mental Health Laura Weiss Roberts, M.D., M.A., 2018-04-19 The chapter authors address life transitions and the university student experience, as well as the challenges of caring for university students with mental health issues. The book has positive strategies, including ways to foster mental health for distinct university student populations. |
| ketamine washington post: The American Journal of Insanity , 1917 |
| ketamine washington post: Love Undetectable Andrew Sullivan, 2014-07-09 I intend to be among the first generation that survives this disease. That was former New Republic editor Andrew Sullivan's first public statement about his HIV diagnosis. Speaking to heterosexual and homosexual audiences alike, this book is about the first steps in that journey of survival. If Sullivan's acclaimed first book, Virtually Normal, was about politics, this long-awaited sequel is about life. In a memoir in the form of three essays, Sullivan asks hard questions about his own life and others'. Can the practice of friendship ever compensate for a life without love? Is sex at war or at peace with spirituality? Can faith endure the randomness of death? Is homosexuality genetic or environmental? Love Undetectable, then, refers to many things: to a virus that, for many, has become undetectable in the bloodstream thanks to new drugs, and to the failed search for love and intimacy that helped spread it; to the love of God, which in times of plague seems particularly hard to find and understand; to a sexual orientation long pathologized and denied any status as an equal form of human love; and to the love between friends, a love ignored when it isn't demeaned, and obscured by the more useful imperatives of family and society. In a work destined to be as controversial as his first book, Sullivan takes on religious authorities and gay activists; talks candidly about his own promiscuity and search for love; revisits Freud in the origins of homosexuality; and makes one of the more memorable modern cases for elevating the virtue of friendship over the satisfactions of love. Scholarly, impassioned, wide-ranging, and embattled, Love Undetectable is a book that is ultimately not about homosexuality or plague, but about humanity and mortality. |
| ketamine washington post: Wherever You Go, There They Are Annabelle Gurwitch, 2018-04-10 A hilarious new collection of essays from New York Times bestselling author Annabelle Gurwitch When Annabelle Gurwitch was a child, surrounded by a cast of epically dysfunctional relatives, she secretly prayed that it was all a terrible mistake. Suffering from a colossal case of “family envy,” Gurwitch began seeking out other forms of community. If she’s learned anything, it’s that no matter how hard you try to escape a crazy family, you just end up in another crazy family. Using her own clan of hucksters and scam artists as inspiration, Wherever You Go, There They Are unpacks and redefines our ideas of community and belonging. In her essays, Gurwitch explores family mythologies, the fragility of sisterhood, the rituals and rites of passage into urban tribes, the seductive charm of a cult, and the spectacularly daunting search for the community where her aging parents will spend the last chapter of their lives. With a wry wit and healthy dose of irresistible self-deprecation, Gurwitch asks: Who and what makes a family in our modern society? Is it our blood relations, the people we work with, pray with, our pets? By turns hilarious and deeply moving, Wherever You Go, There They Are is an irreverent, laugh-out-loud examination of family—both those that we join unwittingly and those we join on purpose. |
| ketamine washington post: The Scientist Lilly, 1996-10-23 The author of Mind of the Dolphin and Center of the Cyclone tells the story of his astonishing discoveries - from his early experiments mapping the brains of monkeys and communication with dolphins to his awesome breakthroughs with consciousness expanding drugs and isolation tanks. His revelations in The Scientist are staggering - his latest report on the solid state conspiracy, on communication with extraterrestrials and the imperative of dolphin/human dialog will grip the reader with its sense of cosmic vision. This expanded edition of The Scientist contains bubbles of consensus reality - text and photos - in the hyperspace narrative. It includes an introduction by Timothy Leary, an afterward by Burgess Meredith, biographical and bibliographic information. The third edition has an update on John Lilly's work with Human/Dolphin communication and the results of recent reintroduction of captive dolphins and other cetaceans to the wild. |
| ketamine washington post: Playing Scared Sara Solovitch, 2015-07-02 Stage fright is one of the human psyche's deepest fears. Over half of British adults name public speaking as their greatest fear, even greater than heights and snakes. Laurence Olivier learned to adapt to it, as have actors Salma Hayek and Hugh Grant. Musicians such as Paul McCartney and Adele have battled it and learned to cope. Playing Scared is Sara Solovitch's journey into the myriad causes of stage fright and the equally diverse ways we can overcome it. As a young child, Sara studied piano and fell in love with music. As a teen, she played Bach and Mozart at her hometown's annual music festival, but was overwhelmed by stage fright, which led her to give up aspirations of becoming a professional pianist. In her late fifties, Sara gave herself a one-year deadline to tame performance anxiety and play before an audience. She resumed music lessons, while exploring meditation, exposure therapy, cognitive therapy, biofeedback and beta blockers, among many other remedies. She practiced performing in airports, hospitals and retirement homes. Finally, the day before her sixtieth birthday, she gave a formal recital for an audience of fifty. Using her own journey as inspiration, Sara has written a thoughtful and insightful cultural history of performance anxiety and a tribute to pursuing personal growth at any age. |
| ketamine washington post: Synthetic Panics Philip Jenkins, 1999-07 America has a long history of drug panics in which countless social problems have been blamed on the devastating effects of some harmful substance. In the last forty years, such panics have often focused on synthetic or designer drugs, like methamphetamine, PCP, Ecstasy, methcathinone, and rave drugs like ketamine, and GHB. Fear of these substances has provided critical justification for the continuing war on drugs. Synthetic Panics traces the history of these anti-drug movements, demonstrating that designer chemicals inspire so much fear not because they are uniquely dangerous, but because they bring into focus deeply rooted public concerns about social and cultural upheaval. Jenkins highlights the role of the mass media in spreading anti-drug hysteria and shows how proponents of the war on drugs use synthetic panics to scapegoat society's others and exacerbate racial, class, and intergenerational conflict. |
| ketamine washington post: The Healing of America T. R. Reid, 2010-08-31 A New York Times Bestseller, with an updated explanation of the 2010 Health Reform Bill Important and powerful . . . a rich tour of health care around the world. —Nicholas Kristof, The New York Times Bringing to bear his talent for explaining complex issues in a clear, engaging way, New York Times bestselling author T. R. Reid visits industrialized democracies around the world--France, Britain, Germany, Japan, and beyond--to provide a revelatory tour of successful, affordable universal health care systems. Now updated with new statistics and a plain-English explanation of the 2010 health care reform bill, The Healing of America is required reading for all those hoping to understand the state of health care in our country, and around the world. T. R. Reid's latest book, A Fine Mess: A Global Quest for a Simpler, Fairer, and More Efficient Tax System, is also available from Penguin Press. |
| ketamine washington post: Something Dangerous Merrill Singer, 2005-06-03 This research-based, theory-driven ethnographic account of the changing underground world of drug use and associated health effects covers the essential ground in a succinct, authoritative fashion. After a thorough outline of the nature and history of drug use dynamics, the author assesses the role of youth in new drug use practices, the impact of illicit drug distribution and the war on drugs, and the public health risks of trends in drug use behavior. Additionally, it considers mechanisms for effective public health response to emergent health risks associated with changing drug use patterns. Because Singer carefully explains all technical terms, uses clarifying examples, and avoids jargon, readers will walk away from this volume with a deeper grasp of this social problem; with appreciation for how change figures into drug use practices; and with knowledge of key social, cultural, political-economic, criminal justice, and health factors. Ideal as a text in the undergraduate classroom, its targeted focus and careful exploration of new concepts and theories also make it appealing for use at more advanced levels. |
| ketamine washington post: Deskbound Kelly Starrett, Glen Cordoza, 2016-04-26 Sitting can wreak havoc on your health, and not just in the form of minor aches and pains. Recent studies show that too much sitting contributes to a host of diseases—from obesity and diabetes to cancer and depression. The typical seated office worker suffers from more musculoskeletal injuries than those workers who do daily manual labor. It turns out that sitting is as much an occupational risk as is lifting heavy weights on the job. The facts are in: sitting literally shortens your life. Your chair is your enemy, and it is murdering your body. In this groundbreaking new book, Dr. Kelly Starrett—renowned physical therapist and author of the New York Times and Wall Street Journal bestseller Becoming a Supple Leopard—unveils a detailed battle plan for surviving our chair-centric society. Deskbound provides creative solutions for reducing the amount of time you spend perched on your backside, as well as strategies for transforming your desk into a dynamic, active workstation that can improve your life. You will learn how to: • Easily identify and fix toxic body positions • Eradicate back, neck, and shoulder pain • Mitigate carpel tunnel syndrome forever • Organize and stabilize your spine and trunk • Walk, hinge, squat, and carry with peak skill • Perform daily body maintenance work using fourteen mobility templates for resolving pain and increasing range of motion Whether your goal is to maximize your performance in or out of the workplace, lose weight, or simply live pain-free, Deskbound will work for you. It is a revolutionary cure for death-by-desk. |
| ketamine washington post: The Eat Fat, Get Thin Cookbook Mark Hyman, 2018-09-11 The companion cookbook to Dr. Hyman's revolutionary Eat Fat, Get Thin, with more than 175 delicious, nutritious, heart- and waist-friendly recipes. Dr. Hyman's Eat Fat, Get Thin radically changed the way we view dietary fat, and proved that the key to losing weight and keeping it off is to eat ample amounts of good fats. Now, Dr. Hyman shares more than 175 mouthwatering recipes to help you incorporate these good fats into your diet and continue on your path to wellness. With easy-to-prepare recipes for every meal -- featuring nuts, coconut oil, avocados, and lots of other superfoods you thought were off limits -- you can achieve fast and sustained weight loss. Your health is a life-long journey, and The Eat Fat, Get Thin Cookbook helps make that journey both doable and delicious. |
| ketamine washington post: Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System Institute of Medicine, Board on Health Sciences Policy, Forum on Neuroscience and Nervous System Disorders, 2011-08-05 Glutamate is the most pervasive neurotransmitter in the central nervous system (CNS). Despite this fact, no validated biological markers, or biomarkers, currently exist for measuring glutamate pathology in CNS disorders or injuries. Glutamate dysfunction has been associated with an extensive range of nervous system diseases and disorders. Problems with how the neurotransmitter glutamate functions in the brain have been linked to a wide variety of disorders, including schizophrenia, Alzheimer's, substance abuse, and traumatic brain injury. These conditions are widespread, affecting a large portion of the United States population, and remain difficult to treat. Efforts to understand, treat, and prevent glutamate-related disorders can be aided by the identification of valid biomarkers. The Institute of Medicine's Forum on Neuroscience and Nervous System Disorders held a workshop on June 21-22, 2010, to explore ways to accelerate the development, validation, and implementation of such biomarkers. Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System: Workshop Summary investigates promising current and emerging technologies, and outlines strategies to procure resources and tools to advance drug development for associated nervous system disorders. Moreover, this report highlights presentations by expert panelists, and the open panel discussions that occurred during the workshop. |
| ketamine washington post: An Outsider's Guide to Humans Camilla Pang PhD, 2021-12-07 An instruction manual for life, love, and relationships by a brilliant young scientist whose Asperger's syndrome allows her--and us--to see ourselves in a different way...and to be better at being human Diagnosed with Autism Spectrum Disorder at the age of eight, Camilla Pang struggled to understand the world around her. Desperate for a solution, she asked her mother if there was an instruction manual for humans that she could consult. With no blueprint to life, Pang began to create her own, using the language she understands best: science. That lifelong project eventually resulted in An Outsider's Guide to Humans, an original and incisive exploration of human nature and the strangeness of social norms, written from the outside looking in--which is helpful to even the most neurotypical thinker. Camilla Pang uses a set of scientific principles to examine life's everyday interactions: - How machine learning can help us sift through data and make more rational decisions - How proteins form strong bonds, and what they teach us about embracing individual differences to form diverse groups - Why understanding thermodynamics is the key to seeking balance over seeking perfection - How prisms refracting light can keep us from getting overwhelmed by our fears and anxieties, breaking them into manageable and separate wavelengths Pang's unique perspective of the world tells us so much about ourselves--who we are and why we do the things we do--and is a fascinating guide to living a happier and more connected life. |
| ketamine washington post: A Birthday Cake for George Washington Ramin Ganeshram, 2016 An expoloration of fifty influential and inspirational women who changed the world. Everyone is buzzing about the president's birthday! Especially George Washington's servants who scurry around the kitchen preparing to make this the best celebration ever. Oh, how George Washington loves his cake! And, oh, how he depends on Hercules, his head chef, to make it for him. Hercules, a slave, takes great pride in baking the president's cake. But this year there is one problem--they are out of sugar. This story, told in the voice of Delia, Hercules' young daughter, is based on real events, and underscores the loving exchange between a very determined father and his eager daughter who are faced with an unspoken, bittersweet reality. |
| ketamine washington post: Galileo Mario Livio, 2021-05-25 An “intriguing and accessible” (Publishers Weekly) interpretation of the life of Galileo Galilei, one of history’s greatest and most fascinating scientists, that sheds new light on his discoveries and how he was challenged by science deniers. “We really need this story now, because we’re living through the next chapter of science denial” (Bill McKibben). Galileo’s story may be more relevant today than ever before. At present, we face enormous crises—such as minimizing the dangers of climate change—because the science behind these threats is erroneously questioned or ignored. Galileo encountered this problem 400 years ago. His discoveries, based on careful observations and ingenious experiments, contradicted conventional wisdom and the teachings of the church at the time. Consequently, in a blatant assault on freedom of thought, his books were forbidden by church authorities. Astrophysicist and bestselling author Mario Livio draws on his own scientific expertise and uses his “gifts as a great storyteller” (The Washington Post) to provide a “refreshing perspective” (Booklist) into how Galileo reached his bold new conclusions about the cosmos and the laws of nature. A freethinker who followed the evidence wherever it led him, Galileo was one of the most significant figures behind the scientific revolution. He believed that every educated person should know science as well as literature, and insisted on reaching the widest audience possible, publishing his books in Italian rather than Latin. Galileo was put on trial with his life in the balance for refusing to renounce his scientific convictions. He remains a hero and inspiration to scientists and all of those who respect science—which, as Livio reminds us in this “admirably clear and concise” (The Times, London) book, remains threatened everyday. |
| ketamine washington post: Feeling Unreal Daphne Simeon M.D., Jeffrey Abugel, 2008-11-07 Everything feels unreal to me, like a dream...I feel detached, like a stranger to myself. These are quotes from actual people, experiencing something they don't understand. What they are saying is being heard by friends, families, and physicians today more than ever before. They do not simply suffer from anxiety, or depression, and they are not schizophrenic. They have found themselves trapped in a very real and singular disorder, yet few even know its name. Their enigmatic state of mind has been studied for more than 100 years, but only recently has it become clear how prevalent and how distinctive it really is. The condition is called Depersonalization Disorder, and Feeling Unreal is the first book to reveal what it's all about. This important volume explores not only Depersonalization, but the philosophical and literary implications of selflessness as well, while providing the latest research, possible treatments, and ways to live and thrive when life seems unreal. For those who still believe that such experiences are merely part of something else, that depersonalization is just a symptom and not a disorder in its own right, Feeling Unreal presents compelling evidence to the contrary. This book provides long-awaited answers for people suffering from Depersonalization Disorder and their loved ones, for mental health professionals, and for all students of the condition, while serving as a wake up call to the medical community at large. |
| ketamine washington post: Welcome to Shirley Kelly McMasters, 2015-12-22 Shirley seemed to be doomed from the beginning. Founded by a Vaudevillian huckster who touted it as a seaside haven despite the sand bar that blocks access to the shore, the town has been plagued by one disaster after another—a UFO, a childhood cancer cluster, and a mysterious federal nuclear laboratory in nearby Brookhaven that leaked toxic nuclear and chemical waste into the aquifer from which the residents unknowingly drew their well water. This is Kelly McMasters' account of growing up in a cursed town and loving it anyway, and of a girl's awakening to tragedy and to a sense of mission. Told in a deliciously engaging voice, Welcome to Shirley balances the bitter with the sweet, the funny with the infuriating, in an unforgettable story of working class Long Island. |
| ketamine washington post: Center of the Cyclone John Lilly, 2009-05-01 In this long-out-of-print counterculture classic, Dr. John C. Lilly takes readers behind the scenes into the inner life of a scientist exploring inner space, or “far-out spaces,” as Lilly called them. The book explains how he derived his theory of the operations of the human mind and brain from his personal experiences and experiments in solitude, isolation, and confinement; LSD; and other methods of mystical experience. It also includes glimpses into Lilly's friendship with such 1960s' notables as Oscar Ichazo, Ram Dass, Timothy Leary, Albert Hofmann, Fritz Perls, and Claudio Narajo. Written for the non-specialist, Center of the Cyclone shows an important, modern thinker at his most personal and profound. |
| ketamine washington post: Antidepressants Matthew Macaluso, Sheldon H. Preskorn, 2019-05-31 This volume reviews the known neurobiology of depression and combines classic data on antidepressant treatments with modern theory on the physiology of depression. It also discusses novel mechanism of action drugs. |
| ketamine washington post: The Extreme Gone Mainstream Cynthia Miller-Idriss, 2019-12-03 This book comes at a time that could hardly be more important. Miller-Idriss opens up a completely new approach to understanding the processes of violent radicalization through subcultural products...(and) will surely become a standard work in the study of right-wing extremism.--Daniel Koehler, founder and director of the German Institute on Radicalization and De-Radicalization Studies.dies. |
| ketamine washington post: The Hanford Plaintiffs Trisha T. Pritikin, 2020-02-25 For more than four decades beginning in 1944, the Hanford nuclear weapons facility in southeastern Washington State secretly blanketed much of the Pacific Northwest with low-dose ionizing radiation, the byproduct of plutonium production. For those who lived in the vicinity, many of them families of Hanford workers, the consequences soon became apparent as rates of illness and death steadily climbed—despite repeated assurances from the Atomic Energy Commission that the facility posed no threat. Trisha T. Pritikin, who has battled a lifetime of debilitating illness to become a lawyer and advocate for her fellow “downwinders,” tells the devastating story of those who were harmed in Hanford’s wake and, seeking answers and justice, were subjected to yet more suffering. At the center of The Hanford Plaintiffs are the oral histories of twenty-four people who joined In re Hanford Nuclear Reservation Litigation, the class-action suit that sought recognition of, and recompense for, the grievous injury knowingly caused by Hanford. Radioactive contamination of American communities was not uncommon during the wartime Manhattan Project, nor during the Cold War nuclear buildup that followed. Pritikin interweaves the stories of people poisoned by Hanford with a parallel account of civilians downwind of the Nevada atomic test site, who suffer from identical radiogenic diseases. Against the heartrending details of personal illness and loss and, ultimately, persistence in the face of a legal system that protects the government on all fronts and at all costs, The Hanford Plaintiffs draws a damning picture of the failure of the US Congress and the Judiciary to defend the American public and to adequately redress a catastrophic wrong. Documenting the legal, medical, and human cost of one community’s struggle for justice, this book conveys in clear and urgent terms the damage done to ordinary Americans in the name of business, progress, and patriotism. |
| ketamine washington post: Neurologic Eliezer J. Sternberg, 2015 Investigates the brain's hidden logic behind seemingly irrational behaviors to explain how conscious and unconscious systems interact in order to create experiences and preserve the sense of self. --Publisher's description. |
| ketamine washington post: Rapid Acting Antidepressants , 2020-06-26 The Advances in Pharmacology series presents a variety of chapters from the best authors in the field. |
| ketamine washington post: A Really Good Day Ayelet Waldman, 2017-01-10 The true story of how a renowned writer’s struggle with mood storms led her to try a remedy as drastic as it is forbidden: microdoses of LSD. Her revealing, fascinating journey provides a window into one family and the complex world of a once-infamous drug seen through new eyes. When a small vial arrives in her mailbox from Lewis Carroll, Ayelet Waldman is at a low point. Her moods have become intolerably severe; she has tried nearly every medication possible; her husband and children are suffering with her. So she opens the vial, places two drops on her tongue, and joins the ranks of an underground but increasingly vocal group of scientists and civilians successfully using therapeutic microdoses of LSD. As Waldman charts her experience over the course of a month--bursts of productivity, sleepless nights, a newfound sense of equanimity--she also explores the history and mythology of LSD, the cutting-edge research into the drug, and the byzantine policies that control it. Drawing on her experience as a federal public defender, and as the mother of teenagers, and her research into the therapeutic value of psychedelics, Waldman has produced a book that is eye-opening, often hilarious, and utterly enthralling. |
| ketamine washington post: Your Psilocybin Mushroom Companion Michelle Janikian, 2019-11-19 Discover the transformational power of psilocybin mushroom with this all-encompassing guide to harnessing magic mushrooms safely and effectively. Thanks to cutting-edge research, the medical and mental health communities are rediscovering the transformative power of psychedelics. And among the psychedelics showing the most promise for opening and healing the mind is the psilocybin mushroom. This friendly, fact-packed companion to magic mushrooms offers a full guide to having the most successful and beneficial experiences—whether you’re a complete newcomer or have dabbled in psychedelics before. Author Michelle Janikian’s straightforward, matter-of-fact approach pairs the most up-to-date research with personal advice and experiences to provide a whole perspective of the pros, cons, and many possibilities of experimenting with psychedelic mushrooms. Whether you’re looking to try mushrooms for healing, personal or spiritual growth, out of curiosity, or for just plain fun, Your Psilocybin Mushroom Companion helps you prepare for every type of journey—from microdosing to full trips and even “trip sitting.” With this book, you’ll find it’s never been easier to use these sacred fungi safely and responsibly. |
| ketamine washington post: Donald Trump v. The United States Michael S. Schmidt, 2023-01-17 NEW YORK TIMES BESTSELLER • With unparalleled reporting, a Pulitzer Prize–winning New York Times reporter chronicles the clash between a president and the officials of his own government who tried to stop him. “A meticulously reported volume that clearly benefits from the author’s extraordinary access . . . [a] startling dissection of the Trump presidency.”—The New York Times Donald Trump v. The United States tells the dramatic, high-stakes story of those who felt compelled to confront and try to contain the most powerful man in the world as he shredded norms and sought to expand his power. Michael S. Schmidt takes readers inside the defining events of the presidency, chronicles them up close, and records the clash between an increasingly emboldened president and those around him, who find themselves trying to thwart the president they had pledged to serve, unsure whether he is acting in the interest of the country, his ego, his family business, or Russia. Through their eyes and ears, we observe an epic struggle. Drawing on secret FBI and White House documents and confidential sources inside federal law enforcement and the West Wing, Donald Trump v. The United States is vital journalism from a Pulitzer Prize–winning reporter that records the shocking reality of a presidency like no other. It is a riveting contemporary history and a lasting account of just how fragile and vulnerable the institutions of American democracy really are. |
| ketamine washington post: Eat Out, Eat Well Hope S. Warshaw, 2015-03-02 The average American will eat out at a restaurant five times this week, and while there are healthy choices available at restaurants, it's not always clear what they are. Fortunately, Hope S. Warshaw has created the ultimate guide to eating healthy—and eating well—in restaurants for people with diabetes, prediabetes, heart health, or those just looking to lose a few pounds. In Eat Out, Eat Well, Hope has created individual strategy guides for a wide variety of cuisines, ranging from everyday burger shops to ethnic choices. Each style of restaurant includes healthy meal options, which recommend certain dishes and portion sizes. There's information on what to avoid and how to go about the making special requests. Each restaurant style also includes nutrient counts to help identify healthy choices. For anyone trying to manage their diabetes but looking to have dinner out, this is an indispensable guide. |
| ketamine washington post: Drugs and Drug Policy Clayton J. Mosher, Scott M. Akins, 2020-11-10 Provides a cross-national perspective on the regulation of drug use by examining and critiquing drug policies in the United States and abroad in terms of their scope, goals, and effectiveness. -- Provided by publisher. |
Schedule I - Steam Community
Schedule I - Schedule I drugs, substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse. - The Drug Enforcement …
Steam Workshop::best guns
May 10, 2018 · TFA Counter-Strike: Online / Counter-Strike Nexon: Zombie SWEPs [Part 2]
Steam Community :: Guide :: Complete list of all reports
Aug 12, 2020 · text convos (all 3), search history (How to get a ketamine prescription, Does ketamine make you forget?, how long before a standard ketamine dose wears off?) Don …
Schedule I - Steam Community
Schedule I - Schedule I drugs, substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse. - The Drug Enforcement …
Steam Workshop::best guns
May 10, 2018 · TFA Counter-Strike: Online / Counter-Strike Nexon: Zombie SWEPs [Part 2]
Steam Community :: Guide :: Complete list of all reports
Aug 12, 2020 · text convos (all 3), search history (How to get a ketamine prescription, Does ketamine make you forget?, how long before a standard ketamine dose wears off?) Don …
