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| journal of leukocyte biology impact factor: Journal of leukocyte biology Federation of American Societies for Experimental Biology, Reticuloendothelial Society, Society for Leukocyte Biology, |
| journal of leukocyte biology impact factor: Understanding Tuberculosis Pere-Joan Cardona, 2012-02-24 Mycobacterium tuberculosis in an attempt to understand the extent to which the bacilli has adapted itself to the host and to its final target. On the other hand, there is a section in which other specialists discuss how to manipulate this immune response to obtain innovative prophylactic and therapeutic approaches to truncate the intimal co-evolution between Mycobacterium tuberculosis and the Homo sapiens. |
| journal of leukocyte biology impact factor: A Text Book of Immunology J.K. Sinha & S. Bhattacharya, |
| journal of leukocyte biology impact factor: Lymphocytes—Advances in Research and Application: 2012 Edition , 2012-12-26 Lymphocytes—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Lymphocytes. The editors have built Lymphocytes—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Lymphocytes in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Lymphocytes—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
| journal of leukocyte biology impact factor: COVID-19 in Zimbabwe Lazarus Chapungu, David Chikodzi, Kaitano Dube, 2023-01-01 This contributed volume, based on papers presented at a conference held in Zimbabwe in mid-2021, interrogates solutions to COVID-19-related problems and issues across agricultural, environmental and water sectors in Zimbabwe and assesses their scientific, economic and practical validity. Across 19 chapters, this volume unpacks the science, economics and politics of the pandemic with a focus on understanding its secondary and tertiary impact on Zimbabwe’s population. The volume is also dedicated to understanding the practical and policy-oriented approaches in tackling the pandemic and confronting the “new normal” of COVID-19. It brings together researchers, development practitioners and policy makers from various disciplines in an endeavour to understand COVID-19 trends and analyse the scientific options for mitigation, containment, innovation and ultimately pre-empt the possible emergence and impacts of other pandemics in the future |
| journal of leukocyte biology impact factor: Locoregional Radionuclide Cancer Therapy Franklin C.L. Wong, 2020-12-08 This book reviews locoregional radionuclide cancer therapies (LRCT). Proving an increasingly viable alternative to radiotherapy, radionuclide therapy includes a diversity of choices of well characterized biochemical and physiologic target molecules. The delivery and retention of radionuclides may be monitored by advanced imaging for exact tissue localization and for real-time dosimetry to enable personalized precision medicine. Radiopharmaceuticals in human cancer therapies are typically delivered in systemic routes but can also be designed for locoregional routes to harness pharmacokinetic advantages of higher payload and lower systemic toxicities. This book explores the latest advancements and clinical considerations of the locoregional approach. Throughout the chapters, the clinical and scientific bases of cancer treatment and the locoregional use of radionculides are explored. Mathematical models of radiation dosimetry of locoregional radionculdies on tissues are studied using common models for multiple commercially available radionuclides. Rodent and canine tumor models of LRCT are compared for selected radionuclides and radiopharmaceuticals. The practical aspects of radiopharmaceuticals production, marketing, transport, as well as radiation protection are reviewed. Finally, the combination of LRCT with immunotherapy and other cancer therapies and prospective future use of LRCT are discussed. This is a guide for practicing nuclear physicians, interventional radiologists, radiation oncologists, radiation scientists, veterinarians and oncologists to expand their knowledge base and to prepare for designing locoregional radionuclide cancer therapies in animals and in humans. |
| journal of leukocyte biology impact factor: Porth's Essentials of Pathophysiology Tommie Norris, 2019-10-17 Vital Disease Information for Your Success in Nursing Ready yourself for the realities of professional nursing practice with this proven approach to pathophysiology. Distilling need-to-know disease content in a clear, accessible format, Porth’sEssentials of Pathophysiology offers concise yet complete coverage of how the body works to help you establish the scientific foundation essential to success in your nursing career. Approachable presentation builds understanding from basic to advanced concepts and defines key terms as you progress. “Chunked” content--including Learning Objectives, Key Points boxes, and Summary Concepts sections--highlights critical points for reflection. Full-color illustrations clarify the clinical manifestations of diseases and disease processes. Review Exercises at the end of each chapter test your retention and identify areas for further study. References provide fast, efficient access to normal laboratory values in both conventional and SI units, as well as a comprehensive glossary. Narrated animations referenced by icons in the text and available online enhance your understanding of the most challenging and clinically relevant concepts. |
| journal of leukocyte biology impact factor: Non-coding RNAs at the Cross-Road of Cardiometabolic Diseases and Cancer Paul Holvoet, 2021-03-26 This book gives insight into the functional role of non-coding RNAs in central pathways contributing to the development of obesity, type 2 diabetes, non-alcoholic fatty liver disease, atherosclerosis, myocardial infarction, cardiomyopathy, and heart failure. It also sheds light on the relationship of this cluster with cancer. Tumor cells, in contrast to cells in cardiometabolic tissues, can regulate this cluster of non-coding RNAs to escape from oxidative stress and anti-tumor immunity and maintain insulin sensitivity, facilitating cancer progression. The book presents a cluster of non-coding RNAs that may be prospectively analyzed in extensive cohort studies to determine their value in risk-predicting machine learning algorithms. In addition, it emphasizes the role of microvesicles in communication between tumor-adjacent tissue, inflammatory cells, and tumor cells, with a special focus on the role of miR-155. The book intends to promote interdisciplinary research. Due to the comprehensive background information provided in each chapter, it is suitable for researchers in academia and industry and for graduate students in biology, bioengineering, and medicine. |
| journal of leukocyte biology impact factor: Brain and Spinal Tumors Lee Roy Morgan, Feyzi Birol Sarica, 2020-01-29 Numerous new concepts and procedures are reviewed and discussed in this book and allude to the transport of drugs to the brain. New radiation concepts are also presented, plus management of toxicities associated with both treatment modalities. It is the goal of this book to provide information and data that will be useful for both researchers and practitioners to develop new approaches for the management of CNS malignancies. |
| journal of leukocyte biology impact factor: Inflammatory Disorders - Part A Rossen Donev, 2020-01-23 Inflammation is a biological response triggered by different stimuli that has in the body a potentially damaging effect. In certain conditions, such as injury or infection, inflammation is a normal, healthy response. However, inflammatory disorders that result in the immune system attacking the body's own cells or tissues may cause abnormal inflammation, which results in chronic pain, redness, swelling, stiffness, and damage to normal tissues. Mechanisms involved in promoting a number of different inflammatory disorders and their targeting for therapeutic benefit have been one of the hottest topics in last few decades. The two consecutive volumes (119 and 120) dedicated to this subject cover a wide spectrum of inflammatory disorders, mechanisms that are believed to cause them and different strategies for managing the inflammatory diseases. - The volume integrates methods for studying inflammatory disorders, mechanisms that trigger these disorders and strategies for managing the inflammatory disorders - It contains timely chapters written by well-renown authorities in their field - The information provided in the volume is well supported by a number of high-quality illustrations, figures and tables, and targets a very wide audience of specialists, researchers and students |
| journal of leukocyte biology impact factor: Visceral Leishmaniasis and Post-kala-azar Dermal Leishmaniasis Veer Singh, Ashish Kumar, 2025-04-03 This reference book explores various aspects of visceral leishmaniasis (VL) and post-kala-azar dermal leishmaniasis (PKDL), including their pathophysiology, treatment options, and disease control strategies. The initial chapter provides an overview of VL, its global impact, and pathogenesis. It also examines the development of PKDL from VL, outlining the transition from the acute form of the disease to the chronic dermal condition. The book further explores the symptoms and diagnosis of both VL and PKDL. Furthermore, the book delves into the immunopathogenesis of both VL and PKDL, shedding light on the complex interactions between the parasite and the host immune system. It reviews the impact of environmental factors, particularly the contamination of arsenic and antimony in drinking water, on the progression of the disease. Lastly, the book discusses preventive measures for PKDL and highlights the major challenges in effectively implementing these strategies. This book serves as a useful resource for researchers, healthcare professionals, and policymakers seeking to deepen their understanding of these diseases and develop effective strategies for their prevention and control. Key features Provides in-depth coverage of VL and PKDL, including pathogenesis, treatment, and disease control strategies Elucidates the symptoms and diagnostic methods for VL and PKDL Offers insights into the complex immunopathogenesis of VL and PKDL, exploring the interactions between parasites and host immune system Examines treatment options for both VL and PKDL, including current therapeutic approaches and emerging strategies Reviews the impact of environmental factors, such as arsenic and antimony contamination, on the disease progression Discusses preventive measures and challenges in implementing effective strategies for PKDL prevention and control |
| journal of leukocyte biology impact factor: New Updates in Tumor Microenvironment Samuel Evans Adunyah, 2025-02-26 This book covers interesting aspects of the tumor microenvironment (TME), its biological functions, regulation, and the challenges it poses to achieving cancer therapy. The TME consists of numerous biological components, including various cell types, cytokines, chemokines, pro-tumor factors, and anti-immune factors, which promote tumor growth, proliferation, tumor survival, anti-apoptosis, and development of tumor drug resistance. This book provides new updates on the biological properties of TME and its impacts on various cancer types. |
| journal of leukocyte biology impact factor: Macrophages Vijay Kumar, 2022-12-14 Macrophages were first discovered in 1882 when Elia Metchnikoff recognized them as important phagocytic cells that can engulf any foreign material, including fungal spores. This discovery has proved to be a milestone in establishing the field of innate immunity. Macrophages are still ruling the area after 140 years of their discovery. This book explores the diverse role of macrophages in vertebrate immunity, parasitic, bacterial, and viral infections, regeneration, inflammation, and neurological diseases. |
| journal of leukocyte biology impact factor: The Immune Response Tak W. Mak, Mary E. Saunders, 2005-11-11 The Immune Response is a unique reference work covering the basic and clinical principles of immunology in a modern and comprehensive fashion. Written in an engaging conversational style, the book conveys the broad scope and fascinating appeal of immunology. The book is beautifully illustrated with superb figures as well as many full color plates. This extraordinary work will be an invaluable resource for lecturers and graduate students in immunology, as well as a vital reference for research scientists and clinicians studying related areas in the life and medical sciences. - Current and thorough 30 chapter reference reviewed by luminaries in the field - Unique 'single voice' ensures consistency of definitions and concepts - Comprehensive and elegant illustrations bring key concepts to life - Provides historical context to allow fuller understanding of key issues - Introductory chapters 1-4 serve as an 'Immunology Primer' before topics are discussed in more detail |
| journal of leukocyte biology impact factor: Encyclopedia of Cancer , 2018-10-12 Encyclopedia of Cancer, Third Edition, Three Volume Set provides a comprehensive, up-to-date overview of the multiple facets of the disease, including research, treatment and societal impact. This new edition comprises 180 contributions from renown experts who present the latest in Mechanisms, Hallmarks of Cancer, Causes of Cancer, Prevention and Control, Diagnosis and Therapy, Pathology and the Genetics of specific Cancers. Readers will find a comprehensive overview of the main areas of oncology, including etiology, mechanisms, prevention, and treatments, from basic science to clinical applications and public health, all set alongside the latest advances and hot topics that have emerged since the previous edition. Topics of interest in the field, including genomics and epigenomics, our understanding of the causes of cancer and the approaches to preventing it (e.g., HPV vaccination, role of obesity and nutrition, molecular markers of environmental exposures), new screening techniques (e.g., low-dose CT for lung cancer) and improvements in the treatment of many cancers (e.g., breast cancer, lung adenocarcinoma) are comprehensively and authoritatively presented. Comprises 180 contributions from renowned experts who present the latest in mechanisms, hallmarks of cancer, causes, prevention and control, diagnosis and therapy, pathology and genetics Presents a comprehensive overview of the main areas of oncology, including etiology, mechanisms, prevention, and treatments, from basic science to clinical applications and public health |
| journal of leukocyte biology impact factor: Studies on Veterinary Medicine Lester Mandelker, Peter Vajdovich, 2011-03-03 This compendium of research material on the role of oxidative stress in animal disease and morbidity examines both the general and the specific. Sourced from scientists, veterinarians, and members of the medical community from around the world, it includes chapters on our wider understanding of the corrosive function of free radicals in cell biology as well as focusing on the interplay between oxidative stress and metabolism in a variety of animal species including dogs, ruminants and birds. Since biogerontologist Denham Harman first posited that free radicals arising from the metabolic activity of oxygen play a central role in aging and disease, a mass of evidence has accumulated linking oxidative stress and biological degradation. We now understand that living in an aerobic environment inevitably leads to the production of free radicals that go on to attack biological membranes and lipoproteins via oxidation in a process called lipid peroxidation. Reacting with carbon-based molecules such as polyunsaturated fatty acids, these free radicals cause oxidative stress and tissue damage. The purpose of Studies on Veterinary Medicine is to inform clinicians, students and others of the plethora of consequences that free radical damage (ROS) has on various cells, tissues, and organs, as well as in different species of animals. The chapters also analyze the effects of oxidative stress on aging and various morbidities such as diabetes, cognitive dysfunction and heart disease. Contributors variously present their interpretation of the role played by oxidative damage in disease and assess the benefits of antioxidant therapies. |
| journal of leukocyte biology impact factor: Educational Rankings Annual 2005 Gale Group, 2004-09 This up-to-date resource presents more than 4,000 national, regional, local and international lists and rankings compiled from hundreds of respected sources. Entries typically include a description of the ranking; background information on criteria for establishing the hierarchy; additional remarks about the ranking; the complete or partial (if extensive) ranking; and a complete source citation for locating additional information if necessary. |
| journal of leukocyte biology impact factor: Ibuprofen K. D. Rainsford, 2015-09-08 Ibuprofen has become one of the foremost pain-relieving medications world-wide with its proven safety and efficacy in a wide variety of painful and inflammatory conditions. It has also been widely investigated for application in a variety of painful and non-pain inflammatory states including cancer and neurodegenerative conditions, reflecting the unique and novel properties of the drug that would never have been foreseen from knowledge of the properties when it was initially discovered. Edited by leading world expert with over 40 years record in research, teaching and as a scientific advisor in the field of anti-inflammatory/analgesic agents. Professor Kim Rainsford is also the founding Editor-in-Chief of the journal, Inflammopharmacology, as well as being an Associate Editor of The Journal of Pharmacy & Pharmacology. Provides a thorough coverage of the medicinal chemistry and pharmaceutics of ibuprofen, and its pharmacokinetics in both humans and animals. Includes molecular, pharmacological and toxicological studies, and discusses the safety and efficacy of non-prescription ibuprofen, including its side effects. Ibuprofen: Discovery, Development & Therapeutics provides a definitive reference on all the main aspects of the chemical and pharmaceutical properties, mechanisms of action and therapeutic uses of ibuprofen including its role in the prevention and treatment of rheumatic conditions, cancer and neurodegenerative conditions such as Alzheimer’s and Parkinson’s diseases. The book has its origins in a volume first published in 1999, since when there have been considerable advances in research and clinical studies on ibuprofen in the treatment of many inflammatory and even non-inflammatory states. This book will prove invaluable to scientists, clinicians, pharmacists and all those who need to know about the actions and uses of anti-inflammatory and analgesic drugs. |
| journal of leukocyte biology impact factor: Bioactive Food as Dietary Interventions for Arthritis and Related Inflammatory Diseases Ronald Ross Watson, Victor R Preedy, 2012-10-22 While diet has long been recognized as having potential to alleviate symptoms of inflammatory diseases including arthritis, lupus and fibromyalgia, research indicates that specific foods offer particular benefits in preventing or mitigating specific symptoms. Bioactive Food as Dietary Interventions for Arthritis and Inflammatory Diseases is the only available resource focused on exploring the latest advances in bioactive food research written for the scientist or professional audience. - The only single-volume resource for scientists and professionals seeking information on how bioactive foods may assist in the treatment of inflammatory disease - Includes coverage of probiotics, prebiotics, and polyphenols - Convenient, efficient and effective source that allows reader to identify potential uses of compounds – or indicate those compounds whose use may in fact be of little or no health benefit - Documents foods that can affect inflammatory disease and ways the associated information could be used to understand other diseases, which share common etiological pathways |
| journal of leukocyte biology impact factor: Leishmaniasis Leonardo de Azevedo Calderon, 2022-04-13 Leishmaniasis is a major global health challenge, affecting approximately 12 million of the poorest people in 100 countries. It is a deforming and fatal disease in the visceral form. Therapies for leishmaniasis are numerically restricted, basically consisting of the administration of miltefosine, pentavalent antimonials, amphotericin B, or pentamidine. This is an important vulnerability against therapy efficiency that must be overcome by the scientific community. This book discusses important aspects of the disease, such as treatment, epidemiology, and molecular and cell biology. The information contained herein is important for young researchers as they seek to develop safe and effective treatments for this neglected tropical disease. |
| journal of leukocyte biology impact factor: Journal of Leukocyte Biology , 1995 |
| journal of leukocyte biology impact factor: Immunopsychiatry Antonio L. Teixeira, Moises E. Bauer, 2019-01-03 In recent years, a dedicated effort has been made to understand the immune dysfunction that is associated with major psychiatric disorders. The expanding knowledge of the immune system as a major homeostatic system has been very helpful in indicating new potential biomarkers and therapeutic targets to reduce the burden of psychiatric disorders. Indeed, immune cells, their secreted molecules, and cell signalling events are highly promising. Yet, the literature on immunology of psychiatric disorders is still dispersed, and only a few attempts have been made to consolidate the current knowledge in this expanding area. This book assembles and presents the available data on the immune/inflammatory dysfunction in psychiatric disorders, indicating the potential of immune mechanisms as either biomarkers or therapeutic targets, as well as discussing the challenges ahead of incorporating this knowledge into clinical practice. An international team of senior experts in the field review all psychiatric disorders in order to provide an integrated, in-depth understanding of the role of immune changes in psychiatric diseases for mental health clinicians as well as for researchers in immunology, psychiatry, neurology, and pharmacology. |
| journal of leukocyte biology impact factor: Advances in Public Health Research and Treatment: 2013 Edition , 2013-06-21 Advances in Public Health Research and Treatment: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Epidemiologic Methods. The editors have built Advances in Public Health Research and Treatment: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Epidemiologic Methods in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Public Health Research and Treatment: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
| journal of leukocyte biology impact factor: Hematology Charles Lawrie, 2012-03-02 Hematology encompasses the physiology and pathology of blood and of the blood-forming organs. In common with other areas of medicine, the pace of change in hematology has been breathtaking over recent years. There are now many treatment options available to the modern hematologist and, happily, a greatly improved outlook for the vast majority of patients with blood disorders and malignancies. Improvements in the clinic reflect, and in many respects are driven by, advances in our scientific understanding of hematological processes under both normal and disease conditions. Hematology - Science and Practice consists of a selection of essays which aim to inform both specialist and non-specialist readers about some of the latest advances in hematology, in both laboratory and clinic. |
| journal of leukocyte biology impact factor: Lindhe's Clinical Periodontology and Implant Dentistry Niklaus P. Lang, Tord Berglundh, William V. Giannobile, Mariano Sanz, 2021-07-28 Discover the latest edition of the cornerstone reference on periodontology and implant dentistry that combines scholarship and science with practical clinical instruction The Seventh Edition of Lindhe's Clinical Periodontology and Implant Dentistry brings together a distinguished team of periodontal specialists and academics who deliver another must-have resource for students, researchers, and practitioners specializing in periodontal care and implant dentistry. Seamlessly integrating the foundational science behind periodontology with practical clinical protocols in two comprehensive volumes, the chapters cover anatomy, microbiology, occlusion trauma, pathology, tissue regeneration, treatment planning protocols, infection control, reconstructive therapy, occlusal and prosthetic therapy, and more. The Seventh Edition of Lindhe's Clinical Periodontology and Implant Dentistry: Provides an introduction to anatomy, including periodontal tissues, the edentulous ridge, the mucosa at teeth and implants, and osseointegration Discusses the epidemiology of periodontal and peri-implant diseases Explores the microbiology, including dental biofilms and calculus, periodontal infections, peri-implant infections, the pathogenesis of gingivitis and periodontitis, and the genetic susceptibility to periodontal disease Includes the latest perio- and peri-implant disease classifications Contains updated evidence-based preventive and treatment modalities for the treatment of periodontal and peri-implant diseases Features the latest evidence-based therapeutic alternatives on the use of dental implants to rehabilitate the lost dentition Perfect for postgraduate dental students, researchers, and practitioners specializing in periodontal care and implant dentistry, Lindhe's Clinical Periodontology and Implant Dentistry continues to be the cornerstone reference work on periodontology. |
| journal of leukocyte biology impact factor: Leukocytes: Advances in Research and Application: 2011 Edition , 2012-01-09 Leukocytes: Advances in Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Leukocytes. The editors have built Leukocytes: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Leukocytes in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Leukocytes: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
| journal of leukocyte biology impact factor: Porth's Pathophysiology Tommie L. Norris, Rupa Lalchandani, 2018-10-08 Publisher’s Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. The 10th edition of Porth’s Pathophysiology: Concepts of Altered Health Statescontinues a legacy of excellence by providing comprehensive, nursing-focused coverage designed to help grasp both the physical and psychological aspects of altered health. The book’s unique emphasis on “concepts of altered health states, as opposed to factual descriptions of diseases and disorders, helps students grasp both the physical and psychological aspects of altered health. Porth’s Pathophysiology: Concepts of Altered Health States Tenth Edition Tommie L. Norris, DNS, RN Meet today’s clinical challenges with the trusted authority in pathophysiology Make the most of your pathophysiology course and master the knowledge to ensure clinical success. Trusted for more than 30 years and updated to reflect today’s nursing challenges, this engaging text makes complex concepts accessible and helps you easily and confidently grasp normal body function, the effects of disease on body systems, and the body’s ability to compensate and adapt. This edition also considers the many technological advances that allow healthcare providers to diagnose earlier and with more accuracy. Highlights of the Tenth Edition Approachable presentation builds understanding from basic to advanced concepts and defines key terms as you progress. “Chunked” content keeps you focused on the most critical information and helps you review salient points efficiently. Unit-Opening Case Studies, which are revisited in one or more chapters in the unit, bring pathophysiology to life and equip you for success in clinical practice. Approximately 1,000 vibrant illustrations clarify the clinical manifestations of diseases and disease processes. Understanding boxes break physiologic processes and phenomena into their sequential parts, providing insight into the many opportunities for disease to disrupt the processes. Key Points boxes and In Summary sections reduce the need for memorization and help you incorporate important points into broader conceptual units. NEW!Pediatric Considerations and Geriatric Considerations boxes in each chapter specify how the chapter content applies to these two special populations. NEW!Concept Mastery Alerts explain topics that students can find confusing. Review Exercises at the end of each chapter test your retention and identify areas for further study. References provide fast, efficient access to normal laboratory values in both conventional and SI units, as well as a comprehensive glossary. Narrated animations referenced by icons in the text and available online enhance your understanding of the most challenging and clinically relevant concepts. |
| journal of leukocyte biology impact factor: Bladder Cancer Abdullah Erdem Canda, 2012-02-01 This book is an invaluable source of knowledge on bladder cancer biology, epidemiology, biomarkers, prognostic factors, and clinical presentation and diagnosis. It is also rich with plenty of up-to-date information, in a well-organized and easy to use format, focusing on the treatment of bladder cancer including surgery, chemotherapy, radiation therapy, immunotherapy, and vaccine therapy. These chapters, written by the experts in their fields, include many interesting, demonstrative and colorful pictures, figures, illustrations and tables. Due to its practicality, this book is recommended reading to anyone interested in bladder cancer. |
| journal of leukocyte biology impact factor: Immunotherapy of Melanoma Anand Rotte, Madhuri Bhandaru, 2016-12-19 This book focusses on the different types of immunotherapeutics that are currently being used and developed for the treatment of melanoma. In recent years, immunotherapy has revolutionized the treatment of metastatic melanoma and other types of cancer. Discussing treatment options for melanoma and the success of immunotherapy along with the challenges of immunotherapy, this book covers epidemiology, susceptibility genes, and treatment recommendations from Society for Immunotherapy of Cancer, as well as immune based therapies such as aldesleukin, Intron-A, Sylatron, Yervoy, Opdivo, Keytruda, Imlygic, DC vaccines and adoptive cell therapy. The detailed information included on the key immune cells involved in anti-tumor immune response and immune-inhibitory mechanisms in tumor microenvironment will aid the understanding of tumor immunology. Both academic as well as industry-based researchers, developing novel anti-cancer therapies, will also benefit from the details of promising molecular targets and immunotherapeutic strategies under investigation. With 132 illustrations including synopsis tables for important information, over 1200 references (majority of which are openly accessible) and details of more than 150 ongoing clinical trials, this book is a valuable source of information for health care providers as well as cancer biologists interested in learning about melanoma and the significant advances made by immunotherapy. |
| journal of leukocyte biology impact factor: Immunobiology of the Shark Sylvia L. Smith, Robert B. Sim, Martin F. Flajnik, 2014-12-04 Sharks belong to the oldest vertebrate species that possess immune systems similar to that of mammals. This makes them a great model species to study the fundamentals of the mammalian immune system. This book describes the cellular, genetic, and molecular specifics of immune systems in sharks and uses them to understand shark immunity as well as the evolution of immune systems in more recently-evolved vertebrates. Written by global experts, the book will be a resource for immunologists, geneticists, ecologists, evolutionary and conservation biologists, and investigators engaged in shark research. |
| journal of leukocyte biology impact factor: Evolving Trends in Kidney Cancer Sashi S. Kommu, Inderbir Gill, 2020-07-22 Kidney cancer imposes a significant cancer burden and its incidence continues to rise globally. Mortality in advanced kidney cancer remains high despite oncological, surgical and multimodal optimisation. Genetic associations, heterogeneity and limitations in early diagnosis through lack of optimal biomarkers add to the challenges. Over the last two decades there has been an exponential increase in diagnostic and therapeutic advances in the management of kidney cancer. The coupling of scientific advances in engineering and technology with oncological therapeutics has recently ushered a renewed optimism. The role of minimally invasive approaches through focal therapy and surgical extirpation using the robotic platform has been unprecedented and paramount. Virtual augmentation and mixed reality platforms have proved useful supplementary tools in surgical planning. The role of surgical simulation and training in development of surgeons with the optimal skill set is essential to provide optimal care. This book is the first in a series that explores the evolving trends in kidney cancer. The focus of the book is broad and includes topics ranging from immunotherapy to surgical simulation. Some chapters explore leading edge concepts while others capture the evolving trends and future concepts. The Editors aim to stimulate the readers to explore the key concepts and to encourage research and innovation along the main themes presented. |
| journal of leukocyte biology impact factor: Nutrition and Physical Activity in Inflammatory Diseases Manohar L. Garg, Lisa G. Wood, 2013 Certain nutrients and physical activity can significantly alter immune function and inflammation. Targeted interventions may be an effective and inexpensive means to improve the inflammation and immune dysfunction associated with chronic diseases. This book defines the relevant underlying biological mechanisms and strengthens our understanding of how nutrients and physical activity impact inflammatory diseases. A useful reference for researchers and students of nutrition, physiology and sports science, it explores the unique aspects of inflammation induced by nutritional deficiencies or activity levels, and their interrelationship. |
| journal of leukocyte biology impact factor: The Oxford Handbook of Psychoneuroimmunology Suzanne Segerstrom, 2012-07-19 This volume collects the state-of-the-art applications of psychological theory to the interactions among the mind, the nervous system, and the immune system, including applications drawn from affective science, developmental psychology, behavioral neuroscience, and clinical psychology. |
| journal of leukocyte biology impact factor: Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity Franck Mauvais-Jarvis, 2017-12-08 The book provides a reference for years to come, written by world-renowned expert investigators studying sex differences, the role of sex hormones, the systems biology of sex, and the genetic contribution of sex chromosomes to metabolic homeostasis and diseases. In this volume, leaders of the pharmaceutical industry present their views on sex-specific drug discovery. Many of the authors presented at the Keystone Symposium on “Sex and gender factors affecting metabolic homeostasis, diabetes and obesity” to be held in March 2017 in Lake Tahoe, CA. This book will generate new knowledge and ideas on the importance of gender biology and medicine from a molecular standpoint to the population level and to provide the methods to study them. It is intended to be a catalyst leading to gender-specific treatments of metabolic diseases. There are fundamental aspects of metabolic homeostasis that are regulated differently in males and females, and influence both the development of diabetes and obesity and the response to pharmacological intervention. Still, most preclinical researchers avoid studying female rodents due to the added complexity of research plans. The consequence is a generation of data that risks being relevant to only half of the population. This is a timely moment to publish a book on sex differences in diseases as NIH leadership has asked scientists to consider sex as a biological variable in preclinical research, to ensure that women get the same benefit of medical research as men. |
| journal of leukocyte biology impact factor: 23/03/2024 Francisco Javier Quintana, 2024-06-11 Mechanisms of Disease Pathogenesis in Multiple Sclerosis summarizes our current understanding on MS and its clinical features and monitoring with available biomarkers, focusing on mechanisms that drive disease pathogenesis and their control by genetic, environmental factors and novel therapies for disease management. The book is written for neurologists, neuroimmunologists and clinical, translational and basic researchers interested in mechanisms of neurodegeneration. Multiple Sclerosis (MS) is an autoimmune disease which targets the central nervous system (CNS). It is the most common cause of non-traumatic neurological disability in young adults with a prevalence of 1 in 1000 and increasing, hence the importance of this book. - Summarizes our current understanding of Multiple Sclerosis - Discusses clinical features and available biomarker monitoring - Focuses on mechanisms that drive disease pathogenesis |
| journal of leukocyte biology impact factor: Annual Review of Nursing Research, Volume 31, 2013 Barbara Smith, 2013-10-28 Print+CourseSmart |
| journal of leukocyte biology impact factor: Cell Biology Reviews , 1991 |
| journal of leukocyte biology impact factor: Crosstalk between Peripheral and Local Immune Response in the Pathophysiology of Stroke and Neurodegeneration Diseases Yuanjian Fang, Lei Huang, Xiangsheng Zhang, Anwen Shao, Jiping Tang, Dirk M. Hermann, 2023-12-27 |
| journal of leukocyte biology impact factor: Impact of Addictive Substances and Behaviours on Individual and Societal Well-being Peter Anderson, Jürgen Rehm, Robin Room, 2015-02-12 Impact of Addictive Substances and Behaviours on Individual and Societal Well-being outlines an innovative and fascinating new framework for understanding the harm that addictive substances and behaviours can cause. Taking a holistic approach and with well-being as a central tenet, it demonstrates how using different methods can lead to a more just and evidence-based approach to dealing with addictions. Presenting the latest and most comprehensive research, the expert team of authors examines the harm caused by addictive substances and behaviour, factors that contribute to addictions, and current European approaches to governing addictive substances and behaviours. It is both legal and illegal drugs, and behaviour that cause harm. For the world as a whole, cigarettes were the second largest cause of ill health and early death in 2010, alcohol the fifth, and illegal drugs the eighteenth. Regular and sustained heavy engagement in addictive substances and behaviour also impacts on quality of life and material living conditions. The well-being framework outlined here for understanding this impact places particular emphasis on the reciprocal relationship between well-being and drug use: well-being can be a driver of the heavy use of addictive substances and behaviours, and also compounds the harm done. Furthermore, the response of society can increase the harm caused by drug use, and stigma, social exclusion, and the actions of the criminal justice system can impair individual and societal well-being considerably. Impact of Addictive Substances and Behaviours on Individual and Societal Well-being is based on the research from ALICE RAP, a multidisciplinary European study of addictive substances and behaviours in contemporary society. A timely addition to the field, this book is essential reading for those wanting to make a real impact in the field of addiction prevention policy, including public managers, practitioners, public health professionals, and stakeholders influencing policy for addictive substances and behaviours, as well as academics. |
| journal of leukocyte biology impact factor: Cellular, Molecular, Physiological, and Behavioral Aspects of Spinal Cord Injury Rajkumar Rajendram, Victor R Preedy, Colin R Martin, 2022-05-10 Spinal injury affects about 10 million people annually worldwide, impacting on the family unit and causing lifelong disabilities, with varied symptoms including paresthesia, spasticity, loss of motor control, and often severe pain. Cellular, Molecular, Physiological, and Behavioral Aspects of Spinal Cord Injury will enhance readers' understanding of the biological and psychological effects of spinal cord injury. Featuring chapters on gene expression, metabolic effects, and behavior, this volume discusses in detail the impact of spinal cord injury to better understand the underlying pathways and processes. The book has applicability for neuroscientists, neurologists, clinicians, and anyone working to better understand these injuries. - Summarizes the neuroscience of spinal cord injury, including cellular and molecular biology - Contains chapter abstracts, key facts, dictionary, and summary points to aid in understanding - Features chapters on signaling and hormonal events - Includes plasticity and gene expression - Examines health and stress behaviors after spinal cord injury |
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