Introduction To Population Genetics

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  introduction to population genetics: An Introduction to Population Genetics Rasmus Nielsen, Montgomery Slatkin, 2013-07-18 This book covers both classical population genetics theory developed in terms of allele and haplotype frequencies and modern population genetics theory developed in terms of coalescent theory. It features applications of theory to problems that arise in the study of human and other populations and assumes little prior knowledge of mathematics.
  introduction to population genetics: Introduction to Population Genetics Richard Halliburton, 2004 Making the theory of population genetics relevant to readers, this book explains the related mathematics with a logical organization. It presents the quantitative aspects of population genetics, and employs examples of human genetics, medical evolution, human evolution, and endangered species. For an introduction to, and understanding of, population genetics.
  introduction to population genetics: Mathematical Population Genetics 1 Warren J. Ewens, 2004-01-09 This is the first of a planned two-volume work discussing the mathematical aspects of population genetics with an emphasis on evolutionary theory. This volume draws heavily from the author’s 1979 classic, but it has been revised and expanded to include recent topics which follow naturally from the treatment in the earlier edition, such as the theory of molecular population genetics.
  introduction to population genetics: Theory of Population Genetics and Evolutionary Ecology Jonathan Roughgarden, Joan Roughgarden, 1996 This is a reprint of a classic which synthesizes population, genetics, and population genetics to form one of the first books on evolutionary ecology. Written by one of the foremost authorities in the field, it is designed as an introduction useful to readers at various levels from diverse backgrounds. It features balanced, readable coverge of both elementary and advanced topics that are essential to those interested in evolutionary biology, ecology, animal behavior, sociobiology, and paleobiology.
  introduction to population genetics: Population Genetics and Microevolutionary Theory Alan R. Templeton, 2006-09-29 The advances made possible by the development of molecular techniques have in recent years revolutionized quantitative genetics and its relevance for population genetics. Population Genetics and Microevolutionary Theory takes a modern approach to population genetics, incorporating modern molecular biology, species-level evolutionary biology, and a thorough acknowledgment of quantitative genetics as the theoretical basis for population genetics. Logically organized into three main sections on population structure and history, genotype-phenotype interactions, and selection/adaptation Extensive use of real examples to illustrate concepts Written in a clear and accessible manner and devoid of complex mathematical equations Includes the author's introduction to background material as well as a conclusion for a handy overview of the field and its modern applications Each chapter ends with a set of review questions and answers Offers helpful general references and Internet links
  introduction to population genetics: An Introduction to Population Genetics Theory J.F. Crow, 2017-01-01 This text book, originally published in 1970, presents the field of population genetics, starting with elementary concepts and leading the reader well into the field. It is concerned mainly with population genetics in a strict sense and deals primarily with natural populations and less fully with the rather similar problems that arise in breading live stock and cul t i vat ed plans . The emphasis is on the behavior of genes and population attributes under natural selection where the most important measure is Darwinian fitness. This text is intended for graduatestudents and advanced undergraduates in genetics and population biology. This book steers a middle course between completely verbal biological arguments and the rigor of the mathematician. The first two-thirds of the book do not require advanced mathematical background. An ordinary knowledge of calculus will suffice. The latter parts of the book, which deal with population stochastically, use more advanced methods.
  introduction to population genetics: Introduction to Conservation Genetics Richard Frankham, David A. Briscoe, Jonathan D. Ballou, 2002-03-14 Genetic diversity, biodiversity, population management.
  introduction to population genetics: Population Genetics Matthew Hamilton, 2009-04-08 This book aims to make population genetics approachable, logical and easily understood. To achieve these goals, the book’s design emphasizes well explained introductions to key principles and predictions. These are augmented with case studies as well as illustrations along with introductions to classical hypotheses and debates. Pedagogical features in the text include: Interact boxes that guide readers step-by-step through computer simulations using public domain software. Math boxes that fully explain mathematical derivations. Methods boxes that give insight into the use of actual genetic data. Numerous Problem boxes are integrated into the text to reinforce concepts as they are encountered. Dedicated website at www.wiley.com/go/hamiltongenetics This text also offers a highly accessible introduction to coalescent theory, the major conceptual advance in population genetics of the last two decades.
  introduction to population genetics: Genetics of Populations Philip Hedrick, 2011-08-24 The Fourth Edition of Genetics of Populations is the most current, comprehensive, and accessible introduction to the field for advanced undergraduate and graduate students, and researchers in genetics, evolution, conservation, and related fields. In the past several years, interest in the application of population genetics principles to new molecular data has increased greatly, and Dr. Hedrick's new edition exemplifies his commitment to keeping pace with this dynamic area of study. Reorganized to allow students to focus more sharply on key material, the Fourth Edition integrates coverage of theoretical issues with a clear presentation of experimental population genetics and empirical data. Drawing examples from both recent and classic studies, and using a variety of organisms to illustrate the vast developments of population genetics, this text provides students and researchers with the most comprehensive resource in the field.
  introduction to population genetics: Population Genetics John H. Gillespie, 2004-08-06 Publisher Description
  introduction to population genetics: Principles of Population Genetics Daniel L. Hartl, Andrew G. Clark, 1997-01-01 Principles of Population Genetics, Third Edition gives a balanced presentation of theory and observation for students at the undergraduate and graduate levels. Applications of the principles discussed are illustrated by numerous worked examples.
  introduction to population genetics: A Primer of Molecular Population Genetics Asher D. Cutter, 2019 What are the genomic signatures of adaptations in DNA? How often does natural selection dictate changes to DNA? How does the ebb and flow in the abundance of individuals over time get marked onto chromosomes to record genetic history? Molecular population genetics seeks to answer such questions by explaining genetic variation and molecular evolution from micro-evolutionary principles. It provides a way to learn about how evolution works and how it shapes species by incorporating molecular details of DNA as the heritable material. It enables us to understand the logic of how mutations originate, change in abundance in populations, and become fixed as DNA sequence divergence between species. With the revolutionary advances in genomic data acquisition, understanding molecular population genetics is now a fundamental requirement for today's life scientists. These concepts apply in analysis of personal genomics, genome-wide association studies, landscape and conservation genetics, forensics, molecular anthropology, and selection scans. This book introduces, in an accessible way, the bare essentials of the theory and practice of molecular population genetics.
  introduction to population genetics: Theoretical Population Genetics J.S. Gale, 2012-12-06 The rise of the neutral theory of molecular evolution seems to have aroused a renewed interest in mathematical population genetics among biologists, who are primarily experimenters rather than theoreticians. This has encouraged me to set out the mathematics of the evolutionary process in a manner that, I hope, will be comprehensible to those with only a basic knowledge of calculus and matrix algebra. I must acknowledge from the start my great debt to my students. Equipped initially with rather limited mathematics, they have pursued the subject with much enthusiasm and success. This has enabled me to try a number of different approaches over the years. I was particularly grateful to Dr L. J. Eaves and Professor W. E. Nance for the opportunity to give a one-semester course at the Medical College of Virginia, and I would like to thank them, their colleagues and their students for the many kindnesses shown to me during my visit. I have concentrated almost entirely on stochastic topics, since these cause the greatest problems for non-mathematicians. The latter are particularly concerned with the range of validity of formulae. A sense of confidence in applying these formulae is, almost certainly, best gained by following their derivation. I have set out proofs in fair detail, since, in my experience, minor points of algebraic manipulation occasionally cause problems. To avoid loss of continuity, I have sometimes put material in notes at the end of chapters.
  introduction to population genetics: My Thoughts on Biological Evolution Motoo Kimura, 2020-07-29 This book, written by Motoo Kimura (1924–94), is a classic in evolutionary biology. In 1968, Kimura proposed the “neutral theory of molecular evolution”, which became the theoretical basis of modern evolutionary studies. After publishing his work in 1983 in the book “Neutral Theory of Molecular Evolution”, Kimura wrote this book in 1988 for the general public. It was originally written in Japanese and is translated here for the first time. In the book, Kimura first summarizes the development of evolutionary theory since Lamarck and Darwin. He then shows how the search for mechanisms of evolution developed into population genetics and describes how the study of molecular evolution matured by taking in the fruits of molecular biology. Kimura proceeds to carefully explain his neutral evolution theory at the molecular level. Finally, he presents his view of the world from an evolutionary perspective. The book has long served as an in-depth introduction to evolutionary biology for students and young researchers in Japan. There has been remarkably rapid progress in the field of bioscience at the molecular level over the past 30 years. Nevertheless, the book remains an important contribution that laid the foundations for what followed in molecular evolutionary studies.
  introduction to population genetics: Population Genetics, Molecular Evolution, and the Neutral Theory Motoo Kimura, 1994 One of this century's leading evolutionary biologists, Motoo Kimura revolutionized the field with his random drift theory of molecular evolution—the neutral theory—and his groundbreaking theoretical work in population genetics. This volume collects 57 of Kimura's most important papers and covers forty years of his diverse and original contributions to our understanding of how genetic variation affects evolutionary change. Kimura's neutral theory, first presented in 1968, challenged the notion that natural selection was the sole directive force in evolution. Arguing that mutations and random drift account for variations at the level of DNA and amino acids, Kimura advanced a theory of evolutionary change that was strongly challenged at first and that eventually earned the respect and interest of evolutionary biologists throughout the world. This volume includes the seminal papers on the neutral theory, as well as many others that cover such topics as population structure, variable selection intensity, the genetics of quantitative characters, inbreeding systems, and reversibility of changes by random drift. Background essays by Naoyuki Takahata examine Kimura's work in relation to its effects and recent developments in each area.
  introduction to population genetics: Understanding Population Genetics Torbjörn Säll, Bengt O. Bengtsson, 2017-07-14 An inspiring introduction to a vital scientific field. The reader is taken through ten mathematical derivations that lead to important results, explaining in a hands-on manner the key concepts and methods of theoretical population genetics. The derivations are carefully worked out and easy to follow. Particular attention is given to the underlying assumptions and the mathematics used. The results are discussed and broadened out with relevant current implications. All topics feature questions with helpful answers. The book is intended for the reader who already knows some population genetics but requires a more comprehensive understanding. It is particularly suited to those who analyse genetic data and wish to better grasp what their results actually mean. It will also be helpful for those who wish to understand how population genetics contributes to the explanation of evolution. Or as the writers claim: If one wants to understand life in all its improbable and amazing richness one must start by understanding population genetics.
  introduction to population genetics: Molecular Plant Taxonomy Pascale Besse, 2014-01-11 Plant taxonomy is an ancient discipline facing new challenges with the current availability of a vast array of molecular approaches which allow reliable genealogy-based classifications. Although the primary focus of plant taxonomy is on the delimitation of species, molecular approaches also provide a better understanding of evolutionary processes, a particularly important issue for some taxonomic complex groups. Molecular Plant Taxonomy: Methods and Protocols describes laboratory protocols based on the use of nucleic acids and chromosomes for plant taxonomy, as well as guidelines for phylogenetic analysis of molecular data. Experts in the field also contribute review and application chapters that will encourage the reader to develop an integrative taxonomy approach, combining nucleic acid and cytogenetic data together with other crucial information (taxonomy, morphology, anatomy, ecology, reproductive biology, biogeography, paleobotany), which will help not only to best circumvent species delimitation but also to resolve the evolutionary processes in play. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Molecular Plant Taxonomy: Methods and Protocols seeks to provide conceptual as well as technical guidelines to plant taxonomists and geneticists.
  introduction to population genetics: A Primer of Population Genetics Daniel L. Hartl, 1988 The use of molecular methods to study genetic polymorphisms has made a familiarity with population genetics essential for any biologist whose work is at the population level. A Primer of Population Genetics, Third Edition provides a concise but comprehensive introduction to population genetics. The four chapters of the book address genetic variation, the causes of evolution, molecular population genetics, and the genetic architecture of complex traits. Chapter-end problems reinforce ideas and, while there are some equations, the emphasis is on explanation rather than derivation.
  introduction to population genetics: Introduction to Forest Genetics Jonathan Wright, 2012-12-02 Introduction to Forest Genetics examines some of the basic genetic concepts typically used in forestry and tree improvement studies, including Mendelian and population genetics. It also describes techniques that are generally useful in tree improvement work, including individual tree selection and breeding, provenance testing, species and racial hybridization, and introduction of exotics. Organized into 19 chapters, this volume begins with an overview of forest genetics and problems associated with forest genetics. It then discusses concepts from basic genetics, including chromosome structure and function; DNA and RNA; nongenetic inheritance; and genotype versus phenotype. Other chapters focus on inbreeding: complete elimination of homozygous recessive trees; mutation and migration; and controlled pollination and vegetative propagation. The book also covers the establishment and measurement of test plantations; general principles and methods of selective breeding; choice of breeding method and type of seed orchard; heritability and genetic gain; geographic variation in Scotch pine and American trees; species and racial hybridization; chromosome studies; and polyploidy and haploidy breeding. This book is a valuable resource for foresters, professional tree breeders, and those with or without previous training in genetics or forestry.
  introduction to population genetics: An Introduction to Population Genetics Ching Chun Li, 1948
  introduction to population genetics: Population Genetics and Evolution Lawrence E. Mettler, Thomas G. Gregg, 1969
  introduction to population genetics: The Geometry of Population Genetics Ethan Akin, 2013-04-09 The differential equations which model the action of selection and recombination are nonlinear equations which are impossible to It is even difficult to describe in general the solve explicitly. Recently, Shahshahani began using qualitative behavior of solutions. differential geometry to study these equations [28]. with this mono graph I hope to show that his ideas illuminate many aspects of pop ulation genetics. Among these are his proof and clarification of Fisher's Fundamental Theorem of Natural Selection and Kimura's Maximum Principle and also the effect of recombination on entropy. We also discover the relationship between two classic measures of 2 genetic distance: the x measure and the arc-cosine measure. There are two large applications. The first is a precise definition of the biological concept of degree of epistasis which applies to general (i.e. frequency dependent) forms of selection. The second is the unexpected appearance of cycling. We show that cycles can occur in the two-locus-two-allele model of selection plus recombination even when the fitness numbers are constant (i.e. no frequency dependence). This work is addressed to two different kinds of readers which accounts for its mode of organization. For the biologist, Chapter I contains a description of the entire work with brief indications of a proof for the harder results. I imagine a reader with some familiarity with linear algebra and systems of differential equations. Ideal background is Hirsch and Smale's text [15].
  introduction to population genetics: The Origins of Theoretical Population Genetics William B. Provine, 2020-07-24 Tracing the development of population genetics through the writings of such luminaries as Darwin, Galton, Pearson, Fisher, Haldane, and Wright, William B. Provine sheds light on this complex field as well as its bearing on other branches of biology.
  introduction to population genetics: Evolutionary Genetics Glenn-Peter Sætre, Mark Ravinet, 2019 With recent technological advances, vast quantities of genetic and genomic data are being generated at an ever-increasing pace. The explosion in access to data has transformed the field of evolutionary genetics. A thorough understanding of evolutionary principles is essential for making sense of this, but new skill sets are also needed to handle and analyze big data. This contemporary textbook covers all the major components of modern evolutionary genetics, carefully explaining fundamental processes such as mutation, natural selection, genetic drift, and speciation. It also draws on a rich literature of exciting and inspiring examples to demonstrate the diversity of evolutionary research, including an emphasis on how evolution and selection has shaped our own species. Practical experience is essential for developing an understanding of how to use genetic and genomic data to analyze and interpret results in meaningful ways. In addition to the main text, a series of online tutorials using the R language serves as an introduction to programming, statistics, and analysis. Indeed the R environment stands out as an ideal all-purpose source platform to handle and analyze such data. The book and its online materials take full advantage of the authors' own experience in working in a post-genomic revolution world, and introduces readers to the plethora of molecular and analytical methods that have only recently become available. Evolutionary Genetics is an advanced but accessible textbook aimed principally at students of various levels (from undergraduate to postgraduate) but also for researchers looking for an updated introduction to modern evolutionary biology and genetics.
  introduction to population genetics: Introduction to Population Ecology Larry L. Rockwood, 2015-06-15 Introduction to Population Ecology, 2nd Edition is a comprehensive textbook covering all aspects of population ecology. It uses a wide variety of field and laboratory examples, botanical to zoological, from the tropics to the tundra, to illustrate the fundamental laws of population ecology. Controversies in population ecology are brought fully up to date in this edition, with many brand new and revised examples and data. Each chapter provides an overview of how population theory has developed, followed by descriptions of laboratory and field studies that have been inspired by the theory. Topics explored include single-species population growth and self-limitation, life histories, metapopulations and a wide range of interspecific interactions including competition, mutualism, parasite-host, predator-prey and plant-herbivore. An additional final chapter, new for the second edition, considers multi-trophic and other complex interactions among species. Throughout the book, the mathematics involved is explained with a step-by-step approach, and graphs and other visual aids are used to present a clear illustration of how the models work. Such features make this an accessible introduction to population ecology; essential reading for undergraduate and graduate students taking courses in population ecology, applied ecology, conservation ecology, and conservation biology, including those with little mathematical experience.
  introduction to population genetics: Information Geometry and Population Genetics Julian Hofrichter, Jürgen Jost, Tat Dat Tran, 2017-02-23 The present monograph develops a versatile and profound mathematical perspective of the Wright--Fisher model of population genetics. This well-known and intensively studied model carries a rich and beautiful mathematical structure, which is uncovered here in a systematic manner. In addition to approaches by means of analysis, combinatorics and PDE, a geometric perspective is brought in through Amari's and Chentsov's information geometry. This concept allows us to calculate many quantities of interest systematically; likewise, the employed global perspective elucidates the stratification of the model in an unprecedented manner. Furthermore, the links to statistical mechanics and large deviation theory are explored and developed into powerful tools. Altogether, the manuscript provides a solid and broad working basis for graduate students and researchers interested in this field.
  introduction to population genetics: Population Genomics: Wildlife Paul A. Hohenlohe, Om P. Rajora, 2020-12-09 Population genomics is revolutionizing wildlife biology, conservation, and management by providing key and novel insights into genetic, population and landscape-level processes in wildlife, with unprecedented power and accuracy. This pioneering book presents the advances and potential of population genomics in wildlife, outlining key population genomics concepts and questions in wildlife biology, population genomics approaches that are specifically applicable to wildlife, and application of population genomics in wildlife population and evolutionary biology, ecology, adaptation and conservation and management. It is important for students, researchers, and wildlife professionals to understand the growing set of population genomics tools that can address issues from delineation of wildlife populations to assessing their capacity to adapt to environmental change. This book brings together leading experts in wildlife population genomics to discuss the key areas of the field, as well as challenges, opportunities and future prospects of wildlife population genomics.
  introduction to population genetics: Molecular Population Genetics Matthew W. Hahn, 2018
  introduction to population genetics: Plant Genetic Conservation Nigel Maxted, Danny Hunter, Rodomiro Ortiz Ríos, 2020-09-10 Plant diversity sustains all animal life, and the genetic diversity within plants underpins global food security. This text provides a practical and theoretical introduction to the strategies and actions to adopt for conserving plant genetic variation, as well as explaining how humans can exploit this diversity for sustainable development. Notably readable, it initially offers current knowledge on the characterization and evaluation of plant genetic resources. The authors then discuss strategies from in situ and ex situ conservation to crop breeding, exploring how these can be used to improve food security in the face of increasing agrobiodiversity loss, human population growth and climate change. Each chapter draws on examples from the literature or the authors' research and includes further reading references. Containing other useful features such as a glossary, it is invaluable for professionals and undergraduate and graduate students in plant sciences, ecology, conservation, genetics and natural resource management.
  introduction to population genetics: Introduction to Population Genetics CROW, James Franklin Crow, Motoo Kimura, 2001-02-02
  introduction to population genetics: Some Mathematical Models from Population Genetics Alison Etheridge, 2011-01-05 This work reflects sixteen hours of lectures delivered by the author at the 2009 St Flour summer school in probability. It provides a rapid introduction to a range of mathematical models that have their origins in theoretical population genetics. The models fall into two classes: forwards in time models for the evolution of frequencies of different genetic types in a population; and backwards in time (coalescent) models that trace out the genealogical relationships between individuals in a sample from the population. Some, like the classical Wright-Fisher model, date right back to the origins of the subject. Others, like the multiple merger coalescents or the spatial Lambda-Fleming-Viot process are much more recent. All share a rich mathematical structure. Biological terms are explained, the models are carefully motivated and tools for their study are presented systematically.
  introduction to population genetics: Population Genetics for Animal Conservation Giorgio Bertorelle, 2009-05-28 Illustrates the power and utility of the synergy between population genetics and conservation biology in animal conservation.
  introduction to population genetics: Principles of Biology Lisa Bartee, Walter Shiner, Catherine Creech, 2017 The Principles of Biology sequence (BI 211, 212 and 213) introduces biology as a scientific discipline for students planning to major in biology and other science disciplines. Laboratories and classroom activities introduce techniques used to study biological processes and provide opportunities for students to develop their ability to conduct research.
  introduction to population genetics: Encyclopedia of Genetics Sydney Brenner, Jeffrey Miller (H), William J. Broughton, 2002
  introduction to population genetics: Concepts of Biology Samantha Fowler, Rebecca Roush, James Wise, 2023-05-12 Black & white print. Concepts of Biology is designed for the typical introductory biology course for nonmajors, covering standard scope and sequence requirements. The text includes interesting applications and conveys the major themes of biology, with content that is meaningful and easy to understand. The book is designed to demonstrate biology concepts and to promote scientific literacy.
  introduction to population genetics: Population Biology of Plant Pathogens , 2015
  introduction to population genetics: Basic Concepts in Population, Quantitative, and Evolutionary Genetics James Franklin Crow, 1986
  introduction to population genetics: Population Genetics Ching Chun Li, 1958
  introduction to population genetics: Primer of Genetic Analysis James N. Thompson, Jr, Jenna J. Hellack, Gerald Braver, David S. Durica, 2007-10-01 This third edition of a student-tested primer provides guided instruction in the analysis and interpretation of genetic principles and problem solving. All core areas of genetics are covered. Each section is introduced with a summary of key concepts and terms. A series of problems, graded from simple to more complex, then allows students to test their understanding of the material. Each question is accompanied by a detailed explanation. This new edition includes additional problems, extensively expanded coverage of molecular biology throughout, new overview chapters, and an expanded glossary.
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