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inorganic medicinal and pharmaceutical chemistry: Inorganic Medicinal and Pharmaceutical Chemistry John H. Block, 1974 |
inorganic medicinal and pharmaceutical chemistry: Essentials of Inorganic Chemistry Katja A. Strohfeldt, 2015-02-16 A comprehensive introduction to inorganic chemistry and, specifically, the science of metal-based drugs, Essentials of Inorganic Chemistry describes the basics of inorganic chemistry, including organometallic chemistry and radiochemistry, from a pharmaceutical perspective. Written for students of pharmacy and pharmacology, pharmaceutical sciences, medicinal chemistry and other health-care related subjects, this accessible text introduces chemical principles with relevant pharmaceutical examples rather than as stand-alone concepts, allowing students to see the relevance of this subject for their future professions. It includes exercises and case studies. |
inorganic medicinal and pharmaceutical chemistry: Modern Inorganic Pharmaceutical Chemistry Clarence A. Discher, Thomas Medwick, Leonard C. Bailey, 1985 Inorganic pharmaceutical chemistry text geared to actual practice in the profession of pharmacy & the health sciences. Provides theoretical & practical background to students. Compendial references. |
inorganic medicinal and pharmaceutical chemistry: Uses of Inorganic Chemistry in Medicine Nicholas P Farrell, 2007-10-31 Metal-based drugs are a commercially important sector of the pharmaceutical business, yet most bioinorganic textbooks lack the space to cover comprehensively the subject of metals in medicine. Uses of Inorganic Chemistry in Medicine approaches an understanding of the topic in a didactic and systematic manner. The field of inorganic chemistry in medicine may usefully be divided into two main categories - drugs which target metal ions in some form, whether free or protein-bound, and secondly, metal-based drugs where the central metal ion is usually the key feature of the mechanism of action. This latter category can further be subdivided into pharmacodynamic and chemotherapeutic applications, as well as those of imaging. The book summarises the chemical and biological studies on clinically used agents of lithium, gold and platinum, as well as highlighting the research on prospective new drugs, including those based on vanadium and manganese. The coverage allows a clear distinction between pharmacodynamic and therapeutic properties of metal-based drugs and focuses not only on those clinical agents in current use, but also on new drugs and uses. This book serves to fill an important niche, bridging bioinorganic and medicinal chemistry and will undoubtedly be of use to senior undergraduates and postgraduates, as well as being an invaluable asset for teachers and researchers in the discipline. |
inorganic medicinal and pharmaceutical chemistry: Experiments in Pharmaceutical Chemistry Charles Dickson, 2014-02-21 Written by an author with more than 40 years of teaching experience in the field, Experiments in Pharmaceutical Chemistry, Second Edition responds to a critical classroom need for material on directed laboratory investigations in biological and pharmaceutical chemistry. This new edition supplies 75 experiments, expanding the range of topics to 22 m |
inorganic medicinal and pharmaceutical chemistry: Pharmaceutical Chemistry - Inorganic (Vol. I). G. R. Chatwal, 2010 The present book Pharmaceutical Chemistry Inorganic, Vol I has been written according to the revised syllabus framed by the Pharmacy council of India as per Education Regulations 1991. In this book, subject matter has been recognised incorporating applicationwise classification(Therapeutic, pharmaceutical etc.) rather than the traditional chemical classification. More emphasis has been further laid by explaining the medical and pharmaceutical terms and to what extent it is justifiable to classify a compound under any of the categories. Inevitably, students will find repetition for some compou. |
inorganic medicinal and pharmaceutical chemistry: Inorganic Medicinal and Pharmaceutical Chemistry John H. Block, |
inorganic medicinal and pharmaceutical chemistry: Textbook of inorganic pharmaceutical and medicinal chemistry J. S. Qadry, 2012 Textbook of Inorganic Pharmaceutical and Medicinal Chemistry in its 11th edition has been meticulously revised in a way that highlights the importance of the role of pharmacy education controlling authorities in India devising study materials that would give them parity with all the courses including the newly introduced Pharm. D. course. The individual chapters are based on my well-known original uniformly designed principles of monographs - like presentation, keeping together drugs' groups with similar therapeutic activities. Actions of drugs on the organism as also actions of organism on the drug (e.g. biotransformation) are - to the extent chemical contemplation is accessible - part of the biochemically oriented pharmaceutical chemistry. The regularly recurring sections of the book refer particularly to structure of drugs, preparation/synthesis, properties, pharmacology, biotransformation, purity tests, analysis, uses, etc. The book is meant for students of all courses in pharmacy and for the interested chemists and medical students. It will further serve the practising hospital pharmacists for continuing education and as a reference book for working pharmacists including those connected with the industry especially the ones engaged in analytical work. |
inorganic medicinal and pharmaceutical chemistry: Ligand Design in Medicinal Inorganic Chemistry Tim Storr, 2014-06-12 Increasing the potency of therapeutic compounds, while limiting side-effects, is a common goal in medicinal chemistry. Ligands that effectively bind metal ions and also include specific features to enhance targeting, reporting, and overall efficacy are driving innovation in areas of disease diagnosis and therapy. Ligand Design in Medicinal Inorganic Chemistry presents the state-of-the-art in ligand design for medicinal inorganic chemistry applications. Each individual chapter describes and explores the application of compounds that either target a disease site, or are activated by a disease-specific biological process. Ligand design is discussed in the following areas: Platinum, Ruthenium, and Gold-containing anticancer agents Emissive metal-based optical probes Metal-based antimalarial agents Metal overload disorders Modulation of metal-protein interactions in neurodegenerative diseases Photoactivatable metal complexes and their use in biology and medicine Radiodiagnostic agents and Magnetic Resonance Imaging (MRI) agents Carbohydrate-containing ligands and Schiff-base ligands in Medicinal Inorganic Chemistry Metalloprotein inhibitors Ligand Design in Medicinal Inorganic Chemistry provides graduate students, industrial chemists and academic researchers with a launching pad for new research in medicinal chemistry. |
inorganic medicinal and pharmaceutical chemistry: Burger's Medicinal Chemistry, Drug Discovery and Development, 8 Volume Set , 2021-04-20 Burger’s Medicinal Chemistry, Drug Discovery and Development Explore the freshly updated flagship reference for medicinal chemists and pharmaceutical professionals The newly revised eighth edition of the eight-volume Burger’s Medicinal Chemistry, Drug Discovery and Development is the latest installment in this celebrated series covering the entirety of the drug development and discovery process. With the addition of expert editors in each subject area, this eight-volume set adds 35 chapters to the extensive existing chapters. New additions include analyses of opioid addiction treatments, antibody and gene therapy for cancer, blood-brain barrier, HIV treatments, and industrial-academic collaboration structures. Along with the incorporation of practical material on drug hunting, the set features sections on drug discovery, drug development, cardiovascular diseases, metabolic diseases, immunology, cancer, anti-Infectives, and CNS disorders. The text continues the legacy of previous volumes in the series by providing recognized, renowned, authoritative, and comprehensive information in the area of drug discovery and development while adding cutting-edge new material on issues like the use of artificial intelligence in medicinal chemistry. Included: Volume 1: Methods in Drug Discovery, edited by Kent D. Stewart Volume 2: Discovering Lead Molecules, edited by Kent D. Stewart Volume 3: Drug Development, edited by Ramnarayan S. Randad and Michael Myers Volume 4: Cardiovascular, Endocrine, and Metabolic Diseases, edited by Scott D. Edmondson Volume 5: Pulmonary, Bone, Immunology, Vitamins, and Autocoid Therapeutic Agents, edited by Bryan H. Norman Volume 6: Cancer, edited by Barry Gold and Donna M. Huryn Volume 7: Anti-Infectives, edited by Roland E. Dolle Volume 8: CNS Disorders, edited by Richard A. Glennon Perfect for research departments in the pharmaceutical and biotechnology industries, Burger’s Medicinal Chemistry, Drug Discovery and Development can be used by graduate students seeking a one-stop reference for drug development and discovery and deserves its place in the libraries of biomedical research institutes, medical, pharmaceutical, and veterinary schools. |
inorganic medicinal and pharmaceutical chemistry: Pharmaceutical Chemistry Christine Bladon, 2002-04-03 Providing a broad introduction to the growing field, this book explores the way in which peptides, proteins, nucleic acids and carbohydrates used therapeutically. With help of numerous illustrations, it covers both the compounds and how therapeutics exert their influence throuhg an understanding of biological processes. * Includes the latest developments in the field * Covers the various strategies behind the development and production of a range of key clinically useful compounds * Focuses on the concepts and ideas of why compounds are developed as pharmaceuticals * Provides many examples and problems Invaluable to all students of chemistry, medicinal and pharmaceutical chemistry, pharmacy and pharmacology. Will also be of interest to researchers and professionals needing a concise, up-to-date account of this subject. |
inorganic medicinal and pharmaceutical chemistry: Bioinorganic Medicinal Chemistry Enzo Alessio, 2011-03-07 This book gives a comprehensive overview about medicinal inorganic chemistry. Topics like targeting strategies, mechanism of action, Pt-based antitumor drugs, radiopharmaceuticals are covered in detail and offer the reader an in-depth overview about this important topic. |
inorganic medicinal and pharmaceutical chemistry: Essentials of Inorganic Chemistry Katja A. Strohfeldt, 2014-12-30 A comprehensive introduction to inorganic chemistry and, specifically, the science of metal-based drugs, Essentials of Inorganic Chemistry describes the basics of inorganic chemistry, including organometallic chemistry and radiochemistry, from a pharmaceutical perspective. Written for students of pharmacy and pharmacology, pharmaceutical sciences, medicinal chemistry and other health-care related subjects, this accessible text introduces chemical principles with relevant pharmaceutical examples rather than as stand-alone concepts, allowing students to see the relevance of this subject for their future professions. It includes exercises and case studies. |
inorganic medicinal and pharmaceutical chemistry: Inorganic General, Medical and Pharmaceutical Chemistry Oscar Oldberg, 1900 |
inorganic medicinal and pharmaceutical chemistry: Textbook of Organic Medicinal and Pharmaceutical Chemistry Charles Owens Wilson, Ole Gisvold, Robert F. Doerge, 1977 |
inorganic medicinal and pharmaceutical chemistry: Pharmaceutical Inorganic Chemistry V. Alagarsamy, 2019-05-27 The main object of this book is to attract the under graduate and post graduate students, to learn the basic theories of Pharmaceutical Inorganic Chemistry. Thus the book is aimed to eliminate the inadequacy in teaching and learning of Pharmaceutical Inorganic Chemistry by providing enormous information about the inorganic compounds used in Pharmacy. -The content of the book is innovative and presented in eight chapters, in a concise form as per the needs of the students. -Incorporation of all the Chemical & Pharmaceutical aspects of the inorganic compounds and their formulations -Describing all the aspects of inorganic pharmaceuticals in easy to understand manner is the first of its kind. -For each chapter, a brief introduction, detailed discussion of the basic theory and applications in pharmacy are provided. -Pharmaceutically important inorganic pharmaceuticals are discussed in detail with the sources, official standards, preparations, physical and chemical properties, tests for identification, uses and their storage conditions. -The principles of assay of each compound, which is difficult to remember by the students is described in a student friendly manner to understand easily and able to reproduce well in examinations, is the first of its kind.- Presentation with simplified way of explanation along with chemical reactions of all compounds helps to reproduce well in examinations. |
inorganic medicinal and pharmaceutical chemistry: Medicinal Chemistry Gareth Thomas, 2011-09-20 Medicinal Chemistry: An Introduction, Second Edition provides a comprehensive, balanced introduction to this evolving and multidisciplinary area of research. Building on the success of the First Edition, this edition has been completely revised and updated to include the latest developments in the field. Written in an accessible style, Medicinal Chemistry: An Introduction, Second Edition carefully explains fundamental principles, assuming little in the way of prior knowledge. The book focuses on the chemical principles used for drug discovery and design covering physiology and biology where relevant. It opens with a broad overview of the subject with subsequent chapters examining topics in greater depth. From the reviews of the First Edition: It contains a wealth of information in a compact form ANGEWANDTE CHEMIE, INTERNATIONAL EDITION Medicinal Chemistry is certainly a text I would chose to teach from for undergraduates. It fills a unique niche in the market place. PHYSICAL SCIENCES AND EDUCATIONAL REVIEWS |
inorganic medicinal and pharmaceutical chemistry: Medicinal Inorganic Chemistry Ajay Kumar Goswami, 2024-12-16 The book is novel in many aspects in the field of Inorganic Medicinal Chemistry which is a less explored area. The salient feature include Theoretical drug designing using PASS, ADMET and Docking studies for organic ligands Hydroxytriazenes and their cobalt complexes. Alternative systems of medicine like Ayurveda , Zuotai and Chinese system. Role of metal complexes in medicine has been extensively reviewed and presented. Extremely useful book for students of Pharma. Medicinal chemistry and doctoral students of chemistry as well as allied branches. |
inorganic medicinal and pharmaceutical chemistry: Metallo-Drugs: Development and Action of Anticancer Agents Astrid Sigel, Helmut Sigel, Eva Freisinger, Roland K.O. Sigel, 2018-02-05 Volume 18, entitled Metallo-Drugs: Development and Action of Anticancer Agents of the series Metal Ions in Life Sciences centers on biological, medicinal inorganic chemistry. The serendipitous discovery of the antitumor activity of cis-diamminodichloroplatinum(II) (cisplatin) by Barnett Rosenberg in the 1960s is a landmark in metallodrug-based chemotherapy. The success of cisplatin in the clinic, followed by oxaliplatin and carboplatin, along with their drawbacks relating mainly to resistance development and severe toxicity, initiated research on polynuclear platinum complexes and on Pt(IV) complexes as prodrugs. Furthermore, the indicated shortcomings led to the exploration of other transition and main group metal ions, among them Ru(II/III), Au(I/III), Ti(IV), V(IV/V), and Ga(III) including also the essential metal ions Fe(II/III), Cu(I/II), and Zn(II). Ionic as well as covalent and non-covalent interactions between structurally very different complexes and biomolecules like nucleic acids, proteins, and carbohydrates are studied and discussed with regard to their possible anticancer actions. Hence, MILS-18 summarizes the research at the forefront of medicinal inorganic chemistry, including studies on the next-generation, tailor-made anticancer drugs. All this and more is treated in an authoritative and timely manner in the 17 stimulating chapters of this book, written by 39 internationally recognized experts from 10 nations (from the US via Europe to China and Australia). The impact of this vibrant research area is manifested by more than 2700 references, nearly 150 illustrations (more than half in color) and several comprehensive tables. Metallo-Drugs: Development and Action of Anticancer Agents is an essential resource for scientists working in the wide range from enzymology, material sciences, analytical, organic, and inorganic biochemistry all the way through to medicine including the clinic ... not forgetting that it also provides excellent information for teaching. |
inorganic medicinal and pharmaceutical chemistry: Pharmaceutical Organic Chemistry V. Alagarsamy, 2020-06-20 Pharmaceutical organic chemistry is the main branch of organic chemistry deals with the study of preparation, structure and reactions of organic compounds. As it deals with all the chemical reactions related to life, study of Pharmaceutical organic chemistry is important. Application of Organic chemistry in the development of pharmaceuticals, resulted in evolving Pharmaceutical organic chemistry. Hence studying Organic chemistry and applying this knowledge in Pharmaceutical substances is called as Pharmaceutical organic chemistry. Organic chemistry forms the basis of biochemistry, in which various aspects of health and diseases are studied. The biochemical knowledge is very important for the practice of nutritional, medical and related life sciences. In addition Organic chemistry paved way for the development of medicinal chemistry, Pharmaceutical organic chemistry, bioinformatics, biotechnology, gene therapy, Pharmacology, pathology, chemical engineering, dental science and so on. Organic substances play such a vital role in our daily life that all of us should know about organic chemistry in order to understand the manner how it influence our life process. |
inorganic medicinal and pharmaceutical chemistry: Chemistry for Pharmacy Students Professor Satyajit D. Sarker, Lutfun Nahar, 2013-05-28 This book has succeeded in covering the basic chemistry essentials required by the pharmaceutical science student... the undergraduate reader, be they chemist, biologist or pharmacist will find this an interesting and valuable read. –Journal of Chemical Biology, May 2009 Chemistry for Pharmacy Students is a student-friendly introduction to the key areas of chemistry required by all pharmacy and pharmaceutical science students. The book provides a comprehensive overview of the various areas of general, organic and natural products chemistry (in relation to drug molecules). Clearly structured to enhance student understanding, the book is divided into six clear sections. The book opens with an overview of general aspects of chemistry and their importance to modern life, with particular emphasis on medicinal applications. The text then moves on to a discussion of the concepts of atomic structure and bonding and the fundamentals of stereochemistry and their significance to pharmacy- in relation to drug action and toxicity. Various aspects of aliphatic, aromatic and heterocyclic chemistry and their pharmaceutical importance are then covered with final chapters looking at organic reactions and their applications to drug discovery and development and natural products chemistry. accessible introduction to the key areas of chemistry required for all pharmacy degree courses student-friendly and written at a level suitable for non-chemistry students includes learning objectives at the beginning of each chapter focuses on the physical properties and actions of drug molecules |
inorganic medicinal and pharmaceutical chemistry: Pharmaceutical Chemistry Chris Rostron, Jill Barber, 2021 Taking medication is a common occurrence for many people, whether it is to soothe an aching head, regulate blood sugars, or to treat life threatening conditions. In the UK alone, over 900 million prescriptions are dispensed every year. Overseeing all of this are pharmacists: experts in medicines and their use.Pharmaceutical Chemistry provides a wide-ranging overview of organic chemistry as applied to the study and practice of pharmacy. Drugs are simply chemicals, so to fully understand their manufacture, formulation, and the way they work in our bodies, a knowledge of organic compounds and their reactions is essential.By reading this book, students will begin to understand how a drug molecule is made; the process that turns it into a medicine; the role the pharmacist has when dispensing that medicine; and what happens in the body when it is taken. Most importantly, the text shows how each of these aspects are integrated, helping you to see the bigger picture. Pharmaceutical Chemistry is available for students and institutions to purchase in a variety of formats, and is supported by online resources.The ebook offers a mobile experience and convenient access: www.oxfordtextbooks.co.uk/ebooks.The online resources include:For students:- Self-assessment questions to help the reader to check and reinforce understanding of the material introduced in each chapter- Bonus material to accompany chapters 3, 7 and 11- Answers to self-check questions from the bookFor registered adopters of the book:- Figures from the book, available to download. |
inorganic medicinal and pharmaceutical chemistry: PHARMACEUTICAL INORGANIC CHEMISTRY Simplified (Practical Book) K. S. Jain, 2020-02 |
inorganic medicinal and pharmaceutical chemistry: Advances in Metallodrugs Shahid Ul Islam, Athar Adil Hashmi, Salman Ahmad Khan, 2020-07-08 This book is organized into 12 important chapters that focus on the progress made by metal-based drugs as anticancer, antibacterial, antiviral, anti-inflammatory, and anti-neurodegenerative agents, as well as highlights the application areas of newly discovered metallodrugs. It can prove beneficial for researchers, investigators and scientists whose work involves inorganic and coordination chemistry, medical science, pharmacy, biotechnology and biomedical engineering. |
inorganic medicinal and pharmaceutical chemistry: Inorganic Chemistry Gary Wulfsberg, 2000-03-16 This is a textbook for advanced undergraduate inorganic chemistry courses, covering elementary inorganic reaction chemistry through to more advanced inorganic theories and topics. The approach integrates bioinorganic, environmental, geological and medicinal material into each chapter, and there is a refreshing empirical approach to problems in which the text emphasizes observations before moving onto theoretical models. There are worked examples and solutions in each chapter combined with chapter-ending study objectives, 40-70 exercises per chapter and experiments for discovery-based learning. |
inorganic medicinal and pharmaceutical chemistry: Textbook of Pharmaceutical Inorganic Chemistry Ali Mohammed, 2018-01-30 The book is intended for use by undergraduate students of pharmacy . It follows the general arrangement and classification of drugs. The general format of presentation of each compound includes introduction preparation physical characters. Chemical properties identification tests purity tests assay methods and uses. |
inorganic medicinal and pharmaceutical chemistry: Medicinal Applications of Coordination Chemistry Chris J Jones, John R Thornback, 2007-10-31 Metals in pharmaceuticals have played an increasingly important role in medicine over the last century, particularly in cancer therapy and diagnostic imaging methods. Medicinal Applications of Coordination Chemistry focuses on the role that transition metals play in clinical applications. Medicinal Applications of Coordination Chemistry begins with a brief historical review and an introduction to the chemistry of d- and f- block metals. Subsequent sections discuss metallodrugs for a number of different applications, the design of new drugs and the relationship between structure and function. Key sections include diagnostic applications of metal compounds in anatomical and functional imaging, and therapeutic applications of metals compounds. This book is ideal for researchers in academia and industry and comes complete with examples of real life applications. |
inorganic medicinal and pharmaceutical chemistry: Biological Inorganic Chemistry Ivano Bertini, 2007 Part A.: Overviews of biological inorganic chemistry : 1. Bioinorganic chemistry and the biogeochemical cycles -- 2. Metal ions and proteins: binding, stability, and folding -- 3. Special cofactors and metal clusters -- 4. Transport and storage of metal ions in biology -- 5. Biominerals and biomineralization -- 6. Metals in medicine. -- Part B.: Metal ion containing biological systems : 1. Metal ion transport and storage -- 2. Hydrolytic chemistry -- 3. Electron transfer, respiration, and photosynthesis -- 4. Oxygen metabolism -- 5. Hydrogen, carbon, and sulfur metabolism -- 6. Metalloenzymes with radical intermediates -- 7. Metal ion receptors and signaling. -- Cell biology, biochemistry, and evolution: Tutorial I. -- Fundamentals of coordination chemistry: Tutorial II. |
inorganic medicinal and pharmaceutical chemistry: Drug Design and Action Joaquín M. Campos Rosa, M. Encarnación Camacho Quesada, 2017-08-21 This two volume book is an excellent introduction to this interdisciplinary area, lying on the interface between organic chemistry, biochemistry and medicine. The authors give a comprehensive overview of the field and outline the actual challenges in pharmaceutical science and industry. Volume 1 introduces the concepts of drug design and drug metabolic processes as well as antibacterial, antiviral and anticancer agents. |
inorganic medicinal and pharmaceutical chemistry: Medicinal Chemistry for Practitioners Jie Jack Li, 2020-06-23 Presenting both a panoramic introduction to the essential disciplines of drug discovery for novice medicinal chemists as well as a useful reference for veteran drug hunters, this book summarizes the state-of-the-art of medicinal chemistry. It covers key drug targets including enzymes, receptors, and ion channels, and hit and lead discovery. The book hen surveys a drug's pharmacokinetics and toxicity, with a solid chapter covering fundamental bioisosteres as a guide to structure-activity relationship investigations. |
inorganic medicinal and pharmaceutical chemistry: Medicinal Organometallic Chemistry Gérard Jaouen, Nils Metzler-Nolte, 2010-09-14 Contents: Gérard Jaouen, Nils Metzler-Nolte : Introduction ; Stéphane GIBAUD and Gérard JAOUEN: Arsenic - based drugs: from Fowler’s solution to modern anticancer chemotherapy; Ana M. Pizarro, Abraha Habtemariam and Peter J. Sadler : Activation Mechanisms for Organometallic Anticancer Complexes; Angela Casini, Christian G. Hartinger, Alexey A. Nazarov, Paul J. Dyson : Organometallic antitumour agents with alternative modes of action; Elizabeth A. Hillard, Anne Vessières, Gerard Jaouen : Ferrocene functionalized endocrine modulators for the treatment of cancer; Megan Hogan and Matthias Tacke : Titanocenes – Cytotoxic and Anti-Angiogenic Chemotherapy Against Advanced Renal-Cell Cancer; Seann P. Mulcahy and Eric Meggers : Organometallics as Structural Scaffolds for Enzyme Inhibitor Design; Christophe Biot and Daniel Dive : Bioorganometallic Chemistry and Malaria; Nils Metzler-Nolte : Biomedical applications of organometal-peptide conjugates; Roger Alberto : Organometallic Radiopharmaceuticals; Brian E. Mann : Carbon Monoxide – an essential signaling molecule. |
inorganic medicinal and pharmaceutical chemistry: Medicinal Chemistry Thomas Nogrady, Donald F. Weaver, 2005-08-11 Fully updated and rewritten by a basic scientist who is also a practicing physician, the third edition of this popular textbook remains comprehensive, authoritative and readable. Taking a receptor-based, target-centered approach, it presents the concepts central to the study of drug action in a logical, mechanistic way grounded on molecular and principles. Students of pharmacy, chemistry and pharmacology, as well as researchers interested in a better understanding of drug design, will find this book an invaluable resource. Starting with an overview of basic principles, Medicinal Chemistry examines the properties of drug molecules, the characteristics of drug receptors, and the nature of drug-receptor interactions. Then it systematically examines the various families of receptors involved in human disease and drug design. The first three classes of receptors are related to endogenous molecules: neurotransmitters, hormones and immunomodulators. Next, receptors associated with cellular organelles (mitochondria, cell nucleus), endogenous macromolecules (membrane proteins, cytoplasmic enzymes) and pathogens (viruses, bacteria) are examined. Through this evaluation of receptors, all the main types of human disease and all major categories of drugs are considered. There have been many changes in the third edition, including a new chapter on the immune system. Because of their increasingly prominent role in drug discovery, molecular modeling techniques, high throughput screening, neuropharmacology and genetics/genomics are given much more attention. The chapter on hormonal therapies has been thoroughly updated and re-organized. Emerging enzyme targets in drug design (e.g. kinases, caspases) are discussed, and recent information on voltage-gated and ligand-gated ion channels has been incorporated. The sections on antihypertensive, antiviral, antibacterial, anti-inflammatory, antiarrhythmic, and anticancer drugs, as well as treatments for hyperlipidemia and peptic ulcer, have been substantially expanded. One new feature will enhance the book's appeal to all readers: clinical-molecular interface sections that facilitate understanding of the treatment of human disease at a molecular level. |
inorganic medicinal and pharmaceutical chemistry: Concise Inorganic Pharmaceutical Chemistry (phar.Che-I) Dr. K. R. Mahadik, 2008-06-07 |
inorganic medicinal and pharmaceutical chemistry: Metals in Medicine James C. Dabrowiak, 2017-05-02 Working from basic chemical principles, Metals in Medicine, 2nd Edition describes a wide range of metal-based agents for treating and diagnosing disease. Thoroughly revised and restructured to reflect significant research activity and advances, this new edition contains extensive updates and new pedagogical features while retaining the popular feature boxes and end-of-chapter problems of the first edition. Topics include: Metallo-Drugs and their action Platinum drugs for treating cancer Anticancer agents beyond cisplatin including ruthenium, gold, titanium and gallium Responsive Metal Complexes Treating arthritis and diabetes with metal complexes Metal complexes for killing bacteria, parasites and viruses Metal ion imbalance and its links to diseases including Alzheimer's, Wilson's and Menkes disease Metal complexes for detecting disease Nanotechnology in medicine Now in full colour, Metals in Medicine, 2nd Edition employs real-life applications and chapter-end summaries alongside feature boxes and problems. It provides a complete and methodical examination of the use of metal complexes in medicine for advanced undergraduate and postgraduate students in medicinal inorganic chemistry, bioinorganic chemistry, biochemistry, pharmacology, biophysics, biology and bioengineering. It is also an invaluable resource for academic researchers and industrial scientists in inorganic chemistry, medicinal chemistry and drug development. |
inorganic medicinal and pharmaceutical chemistry: Pharmaceutical Chemistry (English Edition) Dr. Desh Deepak Pandey, Dr.Arpit Katiyar, Neeraj Kumar, 2024-04-01 Thakur publication Pvt. Ltd. Presenting Pharmaceutical Chemistry in English Edition book for d.pharm- 1st year as per PCI. The Pharmaceutical Chemistry book by Thakur Publication Pvt. Ltd. is a comprehensive guide for first-year students pursuing Diploma in Pharmacy (D.Pharm) as per the guidelines laid down by the Pharmacy Council of India (PCI). The book covers a wide range of topics related to the chemical and physical properties of drugs, drug interactions, and the synthesis and analysis of pharmaceutical compounds. It also includes detailed information on the principles of medicinal chemistry, drug design, and drug metabolism. With clear and concise explanations and numerous illustrations, this book is an essential resource for students to gain a thorough understanding of pharmaceutical chemistry and its applications in the pharmaceutical industry. This dual-color book evokes a sense of satisfaction and fosters a profound grasp of its content among students. |
inorganic medicinal and pharmaceutical chemistry: Inorganic Structural Chemistry Ulrich M]ller, 1993-04-15 An introductory textbook on the structural principles of inorganic-chemical molecules and solids. Traditional concepts and modern approaches are considered and demonstrated with the aid of examples. The most important structural types are examined from different perspectives. |
inorganic medicinal and pharmaceutical chemistry: Chemical Epigenetics Antonello Mai, 2020-03-31 This book presents an authoritative review of the most significant findings about all the epigenetic targets (writers, readers, and erasers) and their implication in physiology and pathology. The book also covers the design, synthesis and biological validation of epigenetic chemical modulators, which can be useful as novel chemotherapeutic agents. Particular attention is given to the chemical mechanisms of action of these molecules and to the drug discovery prose which allows their identification. This book will appeal to students who want to know the extensive progresses made by epigenetics (targets and modulators) in the last years from the beginning, and to specialized scientists who need an instrument to quickly search and check historical and/or updated notices about epigenetics. |
inorganic medicinal and pharmaceutical chemistry: Bioinorganic Medicinal Chemistry Enzo Alessio, 2011-02-25 This book gives a comprehensive overview about medicinal inorganic chemistry. Topics like targeting strategies, mechanism of action, Pt-based antitumor drugs, radiopharmaceuticals are covered in detail and offer the reader an in-depth overview about this important topic. |
Inorganic compound - Wikipedia
An inorganic compound is typically a chemical compound that lacks carbon–hydrogen bonds — that is, a compound that is not an organic compound. [1] [2] The study of inorganic compounds …
Difference Between Organic and Inorganic - Science Notes and …
Aug 24, 2018 · Inorganic chemists study all other types of substances, including salts, metals, and minerals. The main difference between the two classes of substances is that organic …
Inorganic chemistry - Wikipedia
Inorganic chemistry deals with synthesis and behavior of inorganic and organometallic compounds. This field covers chemical compounds that are not carbon-based, which are the …
Inorganic compound | Definition & Examples | Britannica
Inorganic compound, any substance in which two or more chemical elements (usually other than carbon) are combined, nearly always in definite proportions. Compounds of carbon are …
Inorganic chemistry | Definition & Facts | Britannica
Inorganic chemistry, field of science concerned with the composition, properties, and structure of chemical elements and compounds that contain little or no carbon. It is distinguished from …
INORGANIC Definition & Meaning - Merriam-Webster
The meaning of INORGANIC is being or composed of matter other than plant or animal : mineral. How to use inorganic in a sentence.
1.1: What is Inorganic Chemistry? - Chemistry LibreTexts
Organic chemistry is the study of carbon-based molecules because the first molecules that were isolated from living organisms contained carbon. On the other hand, minerals and other non …
What Is Inorganic Chemistry? Examples and Applications
Apr 26, 2025 · Inorganic chemistry is classically defined as the study of the structures, properties, and behaviors of inorganic compounds—those that do not primarily contain carbon-hydrogen …
INORGANIC | English meaning - Cambridge Dictionary
INORGANIC definition: 1. not being or consisting of living material, or (of chemical substances) containing no carbon or…. Learn more.
Chapter 1: Introduction to Inorganic Chemistry
Aug 23, 2023 · Section 1.1: What is Inorganic Chemistry? A generally-accepted definition of inorganic chemistry is the study of non-carbon molecules, or all the elements on the periodic …
Inorganic compound - Wikipedia
An inorganic compound is typically a chemical compound that lacks carbon–hydrogen bonds — that is, a compound that is not an organic compound. [1] [2] The study of inorganic compounds …
Difference Between Organic and Inorganic - Science Notes and …
Aug 24, 2018 · Inorganic chemists study all other types of substances, including salts, metals, and minerals. The main difference between the two classes of substances is that organic compounds …
Inorganic chemistry - Wikipedia
Inorganic chemistry deals with synthesis and behavior of inorganic and organometallic compounds. This field covers chemical compounds that are not carbon-based, which are the subjects of …
Inorganic compound | Definition & Examples | Britannica
Inorganic compound, any substance in which two or more chemical elements (usually other than carbon) are combined, nearly always in definite proportions. Compounds of carbon are classified …
Inorganic chemistry | Definition & Facts | Britannica
Inorganic chemistry, field of science concerned with the composition, properties, and structure of chemical elements and compounds that contain little or no carbon. It is distinguished from …
INORGANIC Definition & Meaning - Merriam-Webster
The meaning of INORGANIC is being or composed of matter other than plant or animal : mineral. How to use inorganic in a sentence.
1.1: What is Inorganic Chemistry? - Chemistry LibreTexts
Organic chemistry is the study of carbon-based molecules because the first molecules that were isolated from living organisms contained carbon. On the other hand, minerals and other non …
What Is Inorganic Chemistry? Examples and Applications
Apr 26, 2025 · Inorganic chemistry is classically defined as the study of the structures, properties, and behaviors of inorganic compounds—those that do not primarily contain carbon-hydrogen …
INORGANIC | English meaning - Cambridge Dictionary
INORGANIC definition: 1. not being or consisting of living material, or (of chemical substances) containing no carbon or…. Learn more.
Chapter 1: Introduction to Inorganic Chemistry
Aug 23, 2023 · Section 1.1: What is Inorganic Chemistry? A generally-accepted definition of inorganic chemistry is the study of non-carbon molecules, or all the elements on the periodic …