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| identical twins identical fates an introduction to epigenetics: Chromatin Regulation and Dynamics Anita Göndör, 2016-10-25 Chromatin Regulation and Dynamics integrates knowledge on the dynamic regulation of primary chromatin fiber with the 3D nuclear architecture, then connects related processes to circadian regulation of cellular metabolic states, representing a paradigm of adaptation to environmental changes. The final chapters discuss the many ways chromatin dynamics can synergize to fundamentally contribute to the development of complex diseases. Chromatin dynamics, which is strategically positioned at the gene-environment interface, is at the core of disease development. As such, Chromatin Regulation and Dynamics, part of the Translational Epigenetics series, facilitates the flow of information between research areas such as chromatin regulation, developmental biology, and epidemiology by focusing on recent findings of the fast-moving field of chromatin regulation. - Presents and discusses novel principles of chromatin regulation and dynamics with a cross-disciplinary perspective - Promotes crosstalk between basic sciences and their applications in medicine - Provides a framework for future studies on complex diseases by integrating various aspects of chromatin biology with cellular metabolic states, with an emphasis on the dynamic nature of chromatin and stochastic principles - Integrates knowledge on the dynamic regulation of primary chromatin fiber with 3D nuclear architecture, then connects related processes to circadian regulation of cellular metabolic states, representing a paradigm of adaptation to environmental changes |
| identical twins identical fates an introduction to epigenetics: Introduction to Epigenetics Renato Paro, Ueli Grossniklaus, Raffaella Santoro, Anton Wutz, 2021-04-23 This open access textbook leads the reader from basic concepts of chromatin structure and function and RNA mechanisms to the understanding of epigenetics, imprinting, regeneration and reprogramming. The textbook treats epigenetic phenomena in animals, as well as plants. Written by four internationally known experts and senior lecturers in this field, it provides a valuable tool for Master- and PhD- students who need to comprehend the principles of epigenetics, or wish to gain a deeper knowledge in this field. After reading this book, the student will: Have an understanding of the basic toolbox of epigenetic regulation Know how genetic and epigenetic information layers are interconnected Be able to explain complex epigenetic phenomena by understanding the structures and principles of the underlying molecular mechanisms Understand how misregulated epigenetic mechanisms can lead to disease |
| identical twins identical fates an introduction to epigenetics: Innate Kevin J. Mitchell, 2018-10-16 A leading neuroscientist explains why your personal traits are more innate than you think What makes you the way you are—and what makes each of us different from everyone else? In Innate, leading neuroscientist and popular science blogger Kevin Mitchell traces human diversity and individual differences to their deepest level: in the wiring of our brains. Deftly guiding us through important new research, including his own groundbreaking work, he explains how variations in the way our brains develop before birth strongly influence our psychology and behavior throughout our lives, shaping our personality, intelligence, sexuality, and even the way we perceive the world. We all share a genetic program for making a human brain, and the program for making a brain like yours is specifically encoded in your DNA. But, as Mitchell explains, the way that program plays out is affected by random processes of development that manifest uniquely in each person, even identical twins. The key insight of Innate is that the combination of these developmental and genetic variations creates innate differences in how our brains are wired—differences that impact all aspects of our psychology—and this insight promises to transform the way we see the interplay of nature and nurture. Innate also explores the genetic and neural underpinnings of disorders such as autism, schizophrenia, and epilepsy, and how our understanding of these conditions is being revolutionized. In addition, the book examines the social and ethical implications of these ideas and of new technologies that may soon offer the means to predict or manipulate human traits. Compelling and original, Innate will change the way you think about why and how we are who we are. |
| identical twins identical fates an introduction to epigenetics: Epigenetics in Allergy and Autoimmunity Christopher Chang, Qianjin Lu, 2020-05-22 This book will address the growing roles of epigenetics in disease pathogenesis, and review the contribution of epigenetic modifications to disease onset and progression. The roles that epigenetics plays in facilitating effects of the environment on allergy and immunologic diseases will be reviewed. The book is divided into three parts – the first is an introduction to epigenetics and the methods that have been developed to study epigenetics, the second addresses epigenetics in allergic diseases and the third part will cover epigenetics in autoimmune diseases. With the rapid expansion of knowledge of how genes are regulated and how this regulation affects disease phenotypes, this book will be attractive to experienced researchers as well as those just launching an epigenetics research program. It will also be of interest to allergist, immunologists, rheumatologists and dermatologist who are engaged in clinical practice as a resource for understanding the basis for personalized and precision medicine. For example, the role that epigenetics plays in the pathogenesis in various allergic and autoimmune disorders and how this determines disease phenotypes will be covered extensively in this book. This book will thus help fill the gap in available resources on epigenetics in allergy and autoimmune diseases. |
| identical twins identical fates an introduction to epigenetics: The Cell Biology of Stem Cells Eran Meshorer, Kathrin Plath, 2011-01-11 Stem cells have been gaining a lot of attention in recent years. Their unique potential to self-renew and differentiate has turned them into an attractive model for the study of basic biological questions such as cell division, replication, transcription, cell fate decisions, and more. With embryonic stem (ES) cells that can generate each cell type in the mammalian body and adult stem cells that are able to give rise to the cells within a given lineage, basic questions at different developmental stages can be addressed. Importantly, both adult and embryonic stem cells provide an excellent tool for cell therapy, making stem cell research ever more pertinent to regenerative medicine. As the title The Cell Biology of Stem Cells suggests, our book deals with multiple aspects of stem cell biology, ranging from their basic molecular characteristics to the in vivo stem cell trafficking of adult stem cells and the adult stem-cell niche, and ends with a visit to regeneration and cell fate reprogramming. In the first chapter, “Early embryonic cell fate decisions in the mouse”, Amy Ralson and Yojiro Yamanaka describe the mechanisms that support early developmental decisions in the mouse pre-implantation embryo and the current understanding of the source of the most immature stem cell types, which includes ES cells, trophoblast stem (TS) cells and extraembryonic endoderm stem (XEN) cells. |
| identical twins identical fates an introduction to epigenetics: Epigenetics of Aging Trygve O. Tollefsbol, 2009-11-11 Recent studies have indicated that epigenetic processes may play a major role in both cellular and organismal aging. These epigenetic processes include not only DNA methylation and histone modifications, but also extend to many other epigenetic mediators such as the polycomb group proteins, chromosomal position effects, and noncoding RNA. The topics of this book range from fundamental changes in DNA methylation in aging to the most recent research on intervention into epigenetic modifications to modulate the aging process. The major topics of epigenetics and aging covered in this book are: 1) DNA methylation and histone modifications in aging; 2) Other epigenetic processes and aging; 3) Impact of epigenetics on aging; 4) Epigenetics of age-related diseases; 5) Epigenetic interventions and aging: and 6) Future directions in epigenetic aging research. The most studied of epigenetic processes, DNA methylation, has been associated with cellular aging and aging of organisms for many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an impact on aging processes such as stem cell aging, control of telomerase, modifications of telomeres, and epigenetic drift can impact the aging process as evident in the recent studies of aging monozygotic twins. Numerous age-related diseases are affected by epigenetic mechanisms. For example, recent studies have shown that DNA methylation is altered in Alzheimer’s disease and autoimmunity. Other prevalent diseases that have been associated with age-related epigenetic changes include cancer and diabetes. Paternal age and epigenetic changes appear to have an effect on schizophrenia and epigenetic silencing has been associated with several of the progeroid syndromes of premature aging. Moreover, the impact of dietary or drug intervention into epigenetic processes as they affect normal aging or age-related diseases is becoming increasingly feasible. |
| identical twins identical fates an introduction to epigenetics: Epigenetic Aspects of Chronic Diseases Helmtrud I. Roach, Felix Bronner, Richard O.C. Oreffo, 2011-04-01 Epigenetic Aspects of Chronic Diseases assembles in comprehensive form what is known about the role of epigenetics in chronic disease development. This book provides new insights into treatment, including modulation of epigenetic regulation. Each chapter gives an outline of a respective disease, explains why epigenetics may be involved in the disease process and then presents the evidence of how changes in epigenetic status contribute to initiation and progress of the disease. The final chapters look towards future therapeutic treatment, based on manipulation of epigenetic aspects. Written by widely published experts, Epigenetic Aspects of Chronic Diseases is a valuable reference tool for clinicians and researchers who investigate and treat chronic diseases, as well as health care personnel, post-doctoral fellows and medical or dental students. |
| identical twins identical fates an introduction to epigenetics: Neurogenesis and Neural Plasticity Catherine Belzung, Peter Wigmore, 2014-07-08 This volume brings together authors working on a wide range of topics to provide an up to date account of the underlying mechanisms and functions of neurogenesis and synaptogenesis in the adult brain. With an increasing understanding of the role of neurogenesis and synaptogenesis it is possible to envisage improvements or novel treatments for a number of diseases and the possibility of harnessing these phenomena to reduce the impact of ageing and to provide mechanisms to repair the brain. |
| identical twins identical fates an introduction to epigenetics: Techniques in Genetic Engineering Isil Aksan Kurnaz, 2015-05-08 Although designed for undergraduates with an interest in molecular biology, biotechnology, and bioengineering, this book-Techniques in Genetic Engineering-IS NOT: a laboratory manual; nor is it a textbook on molecular biology or biochemistry. There is some basic information in the appendices about core concepts such as DNA, RNA, protein, genes, and |
| identical twins identical fates an introduction to epigenetics: International Handbook of Psychology Learning and Teaching Joerg Zumbach, Douglas A. Bernstein, Susanne Narciss, Giuseppina Marsico, 2022-12-16 The International Handbook of Psychology Learning and Teaching is a reference work for psychology learning and teaching worldwide that takes a multi-faceted approach and includes national, international, and intercultural perspectives. Whether readers are interested in the basics of how and what to teach, in training psychology teachers, in taking steps to improve their own teaching, or in planning or implementing research on psychology learning and teaching, this handbook will provide an excellent place to start. Chapters address ideas, issues, and innovations in the teaching of all psychology courses, whether offered in psychology programs or as part of curricula in other disciplines. The book also presents reviews of relevant literature and best practices related to everything from the basics of course organization to the use of teaching technology. Three major sections consisting of several chapters each address “Teaching Psychology in Tertiary (Higher) Education”, “Psychology Learning and Teaching for All Audiences”, and “General Educational and Instructional Approaches to Psychology Learning and Teaching”. |
| identical twins identical fates an introduction to epigenetics: Genetics in Medicine James Scott Thompson, Margaret Wilson Thompson, 1973 |
| identical twins identical fates an introduction to epigenetics: The Palgrave Handbook of Biology and Society Maurizio Meloni, John Cromby, Des Fitzgerald, Stephanie Lloyd, 2017-10-27 This comprehensive handbook synthesizes the often-fractured relationship between the study of biology and the study of society. Bringing together a compelling array of interdisciplinary contributions, the authors demonstrate how nuanced attention to both the biological and social sciences opens up novel perspectives upon some of the most significant sociological, anthropological, philosophical and biological questions of our era. The six sections cover topics ranging from genomics and epigenetics, to neuroscience and psychology to social epidemiology and medicine. The authors collaboratively present state-of-the-art research and perspectives in some of the most intriguing areas of what can be called biosocial and biocultural approaches, demonstrating how quickly we are moving beyond the acrimonious debates that characterized the border between biology and society for most of the twentieth century. This landmark volume will be an extremely valuable resource for scholars and practitioners in all areas of the social and biological sciences. The chapter 'Ten Theses on the Subject of Biology and Politics: Conceptual, Methodological, and Biopolitical Considerations' is open access under a CC BY 4.0 license via link.springer.com. Versions of the chapters 'The Transcendence of the Social', 'Scrutinizing the Epigenetics Revolution', 'Species of Biocapital, 2008, and Speciating Biocapital, 2017' and 'Experimental Entanglements: Social Science and Neuroscience Beyond Interdisciplinarity' are available open access via third parties. For further information please see license information in the chapters or on link.springer.com. |
| identical twins identical fates an introduction to epigenetics: Molecular Exercise Physiology Adam P Sharples, Henning Wackerhage, James P Morton, 2022-05-11 Fully revised and expanded, the second edition of Molecular Exercise Physiology offers a student-friendly introduction. It introduces a history documenting the emergence of molecular biology techniques to investigate exercise physiology, the methodology used, exercise genetics and epigenetics, and the molecular mechanisms that lead to adaptation after different types of exercise, with explicit links to outcomes in sport performance, nutrition, physical activity and clinical exercise. Structured around key topics in sport and exercise science and featuring contributions from pioneering scientists, such as Nobel Prize winners, this edition includes new chapters based on cutting-edge research in epigenetics and muscle memory, satellite cells, exercise in cancer, at altitude, and in hot and cold climates. Chapters include learning objectives, structured guides to further reading, review questions, overviews of work by key researchers and box discussions from important pioneers in the field, making it a complete resource for any molecular exercise physiology course. The book includes cell and molecular biology laboratory methods for dissertation and research projects in molecular exercise physiology and muscle physiology. This book is essential reading for upper-level undergraduate or postgraduate courses in cellular and molecular exercise physiology and muscle physiology. It is a valuable resource for any student with an advanced interest in exercise physiology in both sport performance and clinical settings. |
| identical twins identical fates an introduction to epigenetics: Epigenetics in Human Disease Trygve Tollefsbol, 2012-07-26 Epigenetics is one of the fastest growing fields of sciences, illuminating studies of human diseases by looking beyond genetic make-up and acknowledging that outside factors play a role in gene expression. The goal of this volume is to highlight those diseases or conditions for which we have advanced knowledge of epigenetic factors such as cancer, autoimmune disorders and aging as well as those that are yielding exciting breakthroughs in epigenetics such as diabetes, neurobiological disorders and cardiovascular disease. Where applicable, attempts are made to not only detail the role of epigenetics in the etiology, progression, diagnosis and prognosis of these diseases, but also novel epigenetic approaches to the treatment of these diseases. Chapters are also presented on human imprinting disorders, respiratory diseases, infectious diseases and gynecological and reproductive diseases. Since epigenetics plays a major role in the aging process, advances in the epigenetics of aging are highly relevant to many age-related human diseases. Therefore, this volume closes with chapters on aging epigenetics and breakthroughs that have been made to delay the aging process through epigenetic approaches. With its translational focus, this book will serve as valuable reference for both basic scientists and clinicians alike. Comprehensive coverage of fundamental and emergent science and clinical usage Side-by-side coverage of the basis of epigenetic diseases and their treatments Evaluation of recent epigenetic clinical breakthroughs |
| identical twins identical fates an introduction to epigenetics: Measuring and Interpreting Subjective Wellbeing in Different Cultural Contexts Robert A. Cummins, 2018-05-17 The scientific study of 'wellbeing' involves both objective and subjective variables. While objective wellbeing can be simply measured as tangible aspects of the living environment, measuring subjective wellbeing involves quantifying self-reported feelings. Although reliable and valid measures can be achieved, in a cross-cultural context differences in language and culture present formidable challenges to measurement comparability. This Element begins by describing the behaviour of subjective wellbeing in single cultures, using the theory of homeostasis. Robert A. Cummins then discusses cross-cultural differences in subjective wellbeing, with a focus on measurement invariance as a means of ensuring the validity of comparative results. Cummins proposes that the major barrier to creating such comparability of measurement is a pervasive response bias that differs between cultures. He concludes that current instruments are inadequate to provide valid cross-cultural measures of subjective wellbeing, and that suitable measures may be created as short forms of current scales. |
| identical twins identical fates an introduction to epigenetics: Atlas of Chick Development Ruth Bellairs, Mark Osmond, 2005-09-15 This outstanding work is the only modern book devoted to the chick embryo and has been an essential resource for geneticists, molecular and developmental biologists, and other life scientists who use the chick embryo as their research model. This new enlarged and updated second edition is published in response to continuing demand. The text provides a detailed description of development, from fertilization to hatching, with emphasis on the earlier stages though also covering individual organ systems in detail. There are reviews of the more recent molecular research and a new section highlighting the important landmarks in the history of chick embryology which have had an impact on our understanding of developmental processes. The book is beautifully illustrated with 74 text-figures and over 500 photographs, including nearly 200 new scanning electron micrographs. - Updated and expanded text to accompany diagrams - More than 200 new labelled scanning electron micrographs showing individual tissues in great detail - Reviews of recent molecular research - Discusses the roles of genes such as Hox genes, BMPs, and sonic hedgehog during early development - New sections on genetical anomalies, techniques, and the poultry industry |
| identical twins identical fates an introduction to epigenetics: Biochemistry and Genetics Pretest Self-Assessment and Review 5/E Golder N. Wilson, 2013-06-05 PreTest is the closest you can get to seeing the USMLE Step 1 before you take it! 500 USMLE-style questions and answers! Great for course review and the USMLE Step 1, PreTest asks the right questions so you’ll know the right answers. You’ll find 500 clinical-vignette style questions and answers along with complete explanations of correct and incorrect answers. The content has been reviewed by students who recently passed their exams, so you know you are studying the most relevant and up-to-date material possible. No other study guide targets what you really need to know in order to pass like PreTest! |
| identical twins identical fates an introduction to epigenetics: Essential Medical Genetics Michael Connor, Malcolm Ferguson-Smith, 1997-04-29 Essential Medical Genetics gives a balanced introduction to the basic principles of genetics and how it is applied to the understanding and treatment of diseases with a genetic component. Divided into two sections, basic principles and clinical applications, it covers the information that medical students are taught at the preclinical and clinical levels. This book has been written for clinicians, scientists, counselors and teachers--and any other professionals desiring an understanding of modern medical genetics. |
| identical twins identical fates an introduction to epigenetics: Genes in Conflict Austin BURT, Robert Trivers, Austin Burt, 2009-06-30 Covering all species from yeast to humans, this is the first book to tell the story of selfish genetic elements that act narrowly to advance their own replication at the expense of the larger organism. |
| identical twins identical fates an introduction to epigenetics: Molecular Diagnostics Lela Buckingham, 2012 The first text on molecular diagnostics specifically designed for clinical laboratory science programs is back! This exceptional resource introduces the fundamentals of nucleic acid, as well as more advanced concepts. With a focus on the application of molecular concepts in the clinical laboratory to diagnosis diseases, the 2nd Edition includes important updates and improvements to keep up with the rapidly developing field. Inside youll find in-depth explanations of the principles of molecular-based assays as well as reference material, trouble-shooting tips for the laboratory, and discussions that emphasize the continuing emergence of new diagnostic technologies. |
| identical twins identical fates an introduction to epigenetics: Age of Onset of Mental Disorders Giovanni de Girolamo, Patrick D. McGorry, Norman Sartorius, 2018-11-11 This book presents a thorough and critical review of current knowledge about the age of onset of mental disorders. The opening chapters offer information about the impact of the age of onset on the clinical picture, course, and outcome of physical illnesses, and about the neurobiological implications and correlates of different ages of onset. The impact and correlates of the ages of onset of all the most important mental disorders are then discussed in detail by internationally renowned scientists. The background to the book is the recognition that a better understanding of age of onset makes it possible to estimate the lifetime risk of disorders, helps to elucidate pathogenesis, and facilitates efficient, targeted clinical management. The book will be of value for clinicians, mental health professionals, mental health researchers, epidemiologists, and different stakeholders in the mental health field. |
| identical twins identical fates an introduction to epigenetics: Human Development in the Life Course Tania Zittoun, Jaan Valsiner, Dankert Vedeler, João Salgado, Miguel M. Gonçalves, Dieter Ferring, 2015-10-01 Drawing on philosophy, the history of psychology and the natural sciences, this book proposes a new theoretical foundation for the psychology of the life course. It features the study of unique individual life courses in their social and cultural environment, combining the perspectives of developmental and sociocultural psychology, psychotherapy, learning sciences and geronto-psychology. In particular, the book highlights semiotic processes, specific to human development, that allow us to draw upon past experiences, to choose among alternatives and to plan our futures. Imagination is an important outcome of semiotic processes and enables us to deal with daily constraints and transitions, and promotes the transformation of social representation and symbolic systems - giving each person a unique style, or 'melody', of living. The book concludes by questioning the methodology and epistemology of current life course studies. |
| identical twins identical fates an introduction to epigenetics: Cooperative Evolution Christopher Bryant, Valerie A. Brown, 2021-03-16 Cooperative Evolution offers a fresh account of evolution consistent with Charles Darwin’s own account of a cooperative, inter-connected, buzzing and ever-changing world. Told in accessible language, treating evolutionary change as a cooperative enterprise brings some surprising shifts from the traditional emphasis on the dominance of competition. The book covers many evolutionary changes reconsidered as cooperation. These include the cooperative origins of life, evolution as a spiral rather than a ladder or tree, humans as a part of natural systems rather than the purpose, relationships between natural and social change, and the role of the individual in adaptive radiation onto new ground. The story concludes with a projection of human evolution from the past into the future. ‘Environmental studies courses have needed a book like Cooperative Evolution for a long time. It is a boon for those teaching the complexity of the evolutionary story.’ — Dr John A. Harris, BSc(Hons) MSc PhD, School of Environmental Science, University of Canberra ‘As a regenerative, holistic-thinking farmer I daily witness the results of cooperative evolution as the seasons unfold. A pleasure to read, Cooperative Evolution gives entry to recent thinking on evolutionary processes.’ — David Marsh, MSA, ‘Allendale’, Boorowa, New South Wales, 2018 National Individual Landcarer Award recipient ‘This book is an engaging new look at ideas about evolution as we know it today. In the hands of two eminent biologists, it presents an approachable yet challenging argument. I heartily recommend it.’ — Emeritus Professor Sue Stocklmayer AO, BSc MSc PhD, Centre for the Public Awareness of Science, The Australian National University |
| identical twins identical fates an introduction to epigenetics: The Age of Addiction David T. Courtwright, 2019-05-06 “A mind-blowing tour de force that unwraps the myriad objects of addiction that surround us...Intelligent, incisive, and sometimes grimly entertaining.” —Rod Phillips, author of Alcohol: A History “A fascinating history of corporate America’s efforts to shape our habits and desires.” —Vox We live in an age of addiction, from compulsive gaming and shopping to binge eating and opioid abuse. Sugar can be as habit-forming as cocaine, researchers tell us, and social media apps are deliberately hooking our kids. But what can we do to resist temptations that insidiously rewire our brains? A renowned expert on addiction, David Courtwright reveals how global enterprises have both created and catered to our addictions. The Age of Addiction chronicles the triumph of what he calls “limbic capitalism,” the growing network of competitive businesses targeting the brain pathways responsible for feeling, motivation, and long-term memory. “Compulsively readable...In crisp and playful prose and with plenty of needed humor, Courtwright has written a fascinating history of what we like and why we like it, from the first taste of beer in the ancient Middle East to opioids in West Virginia.” —American Conservative “A sweeping, ambitious account of the evolution of addiction...This bold, thought-provoking synthesis will appeal to fans of ‘big history’ in the tradition of Guns, Germs, and Steel.” —Publishers Weekly |
| identical twins identical fates an introduction to epigenetics: Transposons and the Dynamic Genome Dirk-Henner Lankenau, Jean-Nicolas Volff, 2009-06-30 This volume gives an overview on mobile DNA and how such contradiction to the obligatory stability of genomes can be understood. Obviously, an understanding can only be achieved by cutting deeply into the evolutionary history of life. |
| identical twins identical fates an introduction to epigenetics: Textbook of Clinical Embryology Kevin Coward, Dagan Wells, 2013-10-31 The success of Assisted Reproductive Technology is critically dependent upon the use of well optimized protocols, based upon sound scientific reasoning, empirical observations and evidence of clinical efficacy. Recently, the treatment of infertility has experienced a revolution, with the routine adoption of increasingly specialized molecular biological techniques and advanced methods for the manipulation of gametes and embryos. This textbook – inspired by the postgraduate degree program at the University of Oxford – guides students through the multidisciplinary syllabus essential to ART laboratory practice, from basic culture techniques and micromanipulation to laboratory management and quality assurance, and from endocrinology to molecular biology and research methods. Written for all levels of IVF practitioners, reproductive biologists and technologists involved in human reproductive science, it can be used as a reference manual for all IVF labs and as a textbook by undergraduates, advanced students, scientists and professionals involved in gamete, embryo or stem cell biology. |
| identical twins identical fates an introduction to epigenetics: Predisposed John R. Hibbing, Kevin B. Smith, John R. Alford, 2013-09-23 Buried in many people and operating largely outside the realm of conscious thought are forces inclining us toward liberal or conservative political convictions. Our biology predisposes us to see and understand the world in different ways, not always reason and the careful consideration of facts. These predispositions are in turn responsible for a significant portion of the political and ideological conflict that marks human history. With verve and wit, renowned social scientists John Hibbing, Kevin Smith, and John Alford—pioneers in the field of biopolitics—present overwhelming evidence that people differ politically not just because they grew up in different cultures or were presented with different information. Despite the oft-heard longing for consensus, unity, and peace, the universal rift between conservatives and liberals endures because people have diverse psychological, physiological, and genetic traits. These biological differences influence much of what makes people who they are, including their orientations to politics. Political disputes typically spring from the assumption that those who do not agree with us are shallow, misguided, uninformed, and ignorant. Predisposed suggests instead that political opponents simply experience, process, and respond to the world differently. It follows, then, that the key to getting along politically is not the ability of one side to persuade the other side to see the error of its ways but rather the ability of each side to see that the other is different, not just politically, but physically. Predisposed will change the way you think about politics and partisan conflict. As a bonus, the book includes a Left/Right 20 Questions game to test whether your predispositions lean liberal or conservative. |
| identical twins identical fates an introduction to epigenetics: Mismatch Peter Gluckman, Mark Hanson, 2008-02-14 We have built a world that no longer fits our bodies. Our genes - selected through our evolution - and the many processes by which our development is tuned within the womb, limit our capacity to adapt to the modern urban lifestyle. There is a mismatch. We are seeing the impact of this mismatch in the explosion of diabetes, heart disease and obesity. But it also has consequences in earlier puberty and old age. Bringing together the latest scientific research in evolutionary biology, development, medicine, anthropology and ecology, Peter Gluckman and Mark Hanson, both leading medical scientists, argue that many of our problems as modern-day humans can be understood in terms of this fundamental and growing mismatch. It is an insight that we ignore at our peril. |
| identical twins identical fates an introduction to epigenetics: Complexity Melanie Mitchell, 2009-04-01 What enables individually simple insects like ants to act with such precision and purpose as a group? How do trillions of neurons produce something as extraordinarily complex as consciousness? In this remarkably clear and companionable book, leading complex systems scientist Melanie Mitchell provides an intimate tour of the sciences of complexity, a broad set of efforts that seek to explain how large-scale complex, organized, and adaptive behavior can emerge from simple interactions among myriad individuals. Based on her work at the Santa Fe Institute and drawing on its interdisciplinary strategies, Mitchell brings clarity to the workings of complexity across a broad range of biological, technological, and social phenomena, seeking out the general principles or laws that apply to all of them. Richly illustrated, Complexity: A Guided Tour--winner of the 2010 Phi Beta Kappa Book Award in Science--offers a wide-ranging overview of the ideas underlying complex systems science, the current research at the forefront of this field, and the prospects for its contribution to solving some of the most important scientific questions of our time. |
| identical twins identical fates an introduction to epigenetics: Psychology and Pathophysiological Outcomes of Eating Akikazu Takada, Hubertus Himmerich, 2021 The psychology of eating is regulated by neural mechanisms. When not well controlled, eating may result in disorders and health hazards such as obesity, type 2 diabetes mellitus, and vascular diseases. Lifestyles and cultures influence eating habits, thus there are differences in the prevalence of health problems depending upon living environments. This book examines the psychology and the pathophysiological outcomes of eating. Chapters address such topics as the influence of lifestyle, circadian rhythm, sleep, and fragrant odors on appetite and weight regulation; the impact of glucose, sucrose, lactate, and ketone bodies on the brain; the consequences of glycation stress on the skeletal muscle; and much more. |
| identical twins identical fates an introduction to epigenetics: Epigenetic Mechanisms of Gene Regulation Vincenzo E. A. Russo, Robert A. Martienssen, Arthur D. Riggs, 1996 Many inheritable changes in gene function are not explained by changes in the DNA sequence. Such epigenetic mechanisms are known to influence gene function in most complex organisms and include effects such as transposon function, chromosome imprinting, yeast mating type switching and telomeric silencing. In recent years, epigenetic effects have become a major focus of research activity. This monograph, edited by three well-known biologists from different specialties, is the first to review and synthesize what is known about these effects across all species, particularly from a molecular perspective, and will be of interest to everyone in the fields of molecular biology and genetics. |
| identical twins identical fates an introduction to epigenetics: The Kaiser Wilhelm Institute for Anthropology, Human Heredity and Eugenics, 1927-1945 Hans-Walter Schmuhl, 2008-01-14 When the Kaiser Wilhelm Institute for Anthropology, Human Heredity and Eugenics opened its doors in 1927, it could rely on wide political approval. In 1933 the institute and its founding director Eugen Fischer came under pressure to adjust, which they were able to ward off through Selbstgleichschaltung (auto-coordination). The Third Reich brought about a mutual beneficial servicing of science and politics. With their research into hereditary health and racial policies the institute’s employees provided the Brownshirt rulers with legitimating grounds. This volume traces the history of the Kaiser Wilhelm Institute for Anthropology, Human Heredity and Eugenics between democracy and dictatorship. Attention is turned to the haunting transformation of the research program, the institute’s integration into the national and international science panorama, and its relationship to the ruling power. The volume also confronts the institute’s interconnection to the political crimes of Nazi Germany terminating in bestial medical crimes. |
| identical twins identical fates an introduction to epigenetics: Biological Physics Philip Nelson, 2013-12-16 Biological Physics focuses on new results in molecular motors, self-assembly, and single-molecule manipulation that have revolutionized the field in recent years, and integrates these topics with classical results. The text also provides foundational material for the emerging field of nanotechnology. |
| identical twins identical fates an introduction to epigenetics: Single-cell Sequencing and Methylation Buwei Yu, Jiaqiang Zhang, Yiming Zeng, Li Li, Xiangdong Wang, 2020-10-14 With the rapid development of biotechnologies, single-cell sequencing has become an important tool for understanding the molecular mechanisms of diseases, defining cellular heterogeneities and characteristics, and identifying intercellular communications and single-cell-based biomarkers. Providing a clear overview of the clinical applications, the book presents state-of-the-art information on immune cell function, cancer progression, infection, and inflammation gained from single-cell DNA or RNA sequencing. Furthermore, it explores the role of target gene methylation in the pathogenesis of diseases, with a focus on respiratory cancer, infection and chronic diseases. As such it is a valuable resource for clinical researchers and physicians, allowing them to refresh their knowledge and improve early diagnosis and therapy for patients. |
| identical twins identical fates an introduction to epigenetics: Explorations Beth Shook, Katie Nelson, Kelsie Aguilera, 2019-12-20 Welcome to Explorations and biological anthropology! An electronic version of this textbook is available free of charge at the Society for Anthropology in Community Colleges' webpage here: www.explorations.americananthro.org |
| identical twins identical fates an introduction to epigenetics: Studying Drug Abuse Lee N. Robins, 1985 |
| identical twins identical fates an introduction to epigenetics: Oral Histology - Development Antonio Nanci, 2010-12-15 Accompanying CD-ROM contains ... 150 color images with legends, 472 book figures with legends, 438 multiple choice test questions, and 119 interactive drag-and-drop exercises. -- from CD-ROM Welcome screen. |
| identical twins identical fates an introduction to epigenetics: Understanding Pathophysiology Sue Huether, Kathryn McCance, 2012 |
| identical twins identical fates an introduction to epigenetics: Bioinformatics and Systems Biology Frederick Marcus, 2008-07-31 Collaborative research in bioinformatics and systems biology is a key element of modern biology and health research. This book highlights and provides access to many of the methods, environments, results and resources involved, including integral laboratory data generation and experimentation and clinical activities. Collaborative projects embody a research paradigm that connects many of the top scientists, institutions, their resources and research worldwide, resulting in first-class contributions to bioinformatics and systems biology. Central themes include describing processes and results in collaborative research projects using computational biology and providing a guide for researchers to access them. The book is also a practical guide on how science is managed. It shows how collaborative researchers are putting results together in a way accessible to the entire biomedical community. |
| identical twins identical fates an introduction to epigenetics: The Kaufmann Protocol Sandra Kaufmann, 2018-07-31 The Protocol is the first ever organized system that answers the question why we age as organisms. It offers a personalized program to legitimately curb the effects of time on the human body--Page 4 of cover. |
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Dec 16, 2022 · Identical twins (monozygotic twins) occur when a single fertilized egg splits and develops into two individuals. Eight to 12 days after conception, the embryonic layers that split …
Menopause hormone therapy: Is it right for you? - Mayo Clinic
Apr 18, 2025 · Menopause hormone therapy is medicine with female hormones. It's taken to replace the estrogen the body stops making after menopause, which is when periods stop for …
Perimenopause - Diagnosis and treatment - Mayo Clinic
May 25, 2023 · The term "bioidentical" implies that the hormones in the product are chemically identical to those your body produces. However, compounded bioidentical hormones aren't …
replicate 和 duplicate 有什么不同? - 知乎
Copy, Replicate, Duplicate 三者的不同： Copy 仅仅是照抄、照搬，可以是从头到尾全部丝毫不变地从A照搬到B上，也可以是丝毫不差地照抄照搬A的某一、或某几部分到 B上。
Long COVID: Lasting effects of COVID-19 - Mayo Clinic
Aug 23, 2024 · After any coronavirus disease 2019 (COVID-19) illness, no matter how serious, some people report that symptoms stay for months. This lingering illness has often been called …
Cholesterol-lowering supplements may be helpful - Mayo Clinic
Nov 10, 2022 · Some red yeast rice products contain a substance (monacolin K) that is chemically identical to the active ingredient in lovastatin (Altoprev), a prescription medication that lowers …
Cold or allergy: Which is it? - Mayo Clinic
Feb 13, 2024 · You can tell the difference between a cold and a seasonal allergy by key symptoms and how regularly symptoms appear. Colds are caused by your immune system's …
Bone marrow transplant - Mayo Clinic
Jan 31, 2025 · Bone marrow is the spongy tissue inside some bones. Its job is to produce blood cells. If your bone marrow isn't functioning properly because of cancer or another disease, you …
Bioidentical hormones: Are they safer? - Mayo Clinic
Oct 3, 2024 · No, they aren't. The hormones marketed as "bioidentical" and "natural" aren't safer than hormones used in traditional hormone therapy. And there's no proof that they work any …
Twin pregnancy: Getting ready for twins or multiples
Dec 17, 2024 · Identical twins might share a placenta and an amniotic and chorionic sac. Or the twins might share a placenta and each have separate sacs. Both have the same genetic …
Conjoined twins - Symptoms and causes - Mayo Clinic
Dec 16, 2022 · Identical twins (monozygotic twins) occur when a single fertilized egg splits and develops into two individuals. Eight to 12 days after conception, the embryonic layers that split …
Menopause hormone therapy: Is it right for you? - Mayo Clinic
Apr 18, 2025 · Menopause hormone therapy is medicine with female hormones. It's taken to replace the estrogen the body stops making after menopause, which is when periods stop for …
Perimenopause - Diagnosis and treatment - Mayo Clinic
May 25, 2023 · The term "bioidentical" implies that the hormones in the product are chemically identical to those your body produces. However, compounded bioidentical hormones aren't …
replicate 和 duplicate 有什么不同? - 知乎
Copy, Replicate, Duplicate 三者的不同： Copy 仅仅是照抄、照搬，可以是从头到尾全部丝毫不变地从A照搬到B上，也可以是丝毫不差地照抄照搬A的某一、或某几部分到 B上。
Long COVID: Lasting effects of COVID-19 - Mayo Clinic
Aug 23, 2024 · After any coronavirus disease 2019 (COVID-19) illness, no matter how serious, some people report that symptoms stay for months. This lingering illness has often been called …
Cholesterol-lowering supplements may be helpful - Mayo Clinic
Nov 10, 2022 · Some red yeast rice products contain a substance (monacolin K) that is chemically identical to the active ingredient in lovastatin (Altoprev), a prescription medication that lowers …
Cold or allergy: Which is it? - Mayo Clinic
Feb 13, 2024 · You can tell the difference between a cold and a seasonal allergy by key symptoms and how regularly symptoms appear. Colds are caused by your immune system's …
Bone marrow transplant - Mayo Clinic
Jan 31, 2025 · Bone marrow is the spongy tissue inside some bones. Its job is to produce blood cells. If your bone marrow isn't functioning properly because of cancer or another disease, you …
