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| high resolution electrophoresis: High-resolution Electrophoresis and Immunofixation David F. Keren, 1987 A text that acquaints readers with the available methodologies and instrumentation for performing high-resolution electrophoresis and immunofixation; presents a strategy for using these procedures to facilitate the diagnosis of a variety of serum protein abnormalities; and presents a large number of cases to illustrate the uses of these new procedures. This edition (1st ed., 1987) has been largely rewritten to reflect the significant advances that have been made both in the technology of serum protein electrophoresis and in the knowledge about the electrophoretic patterns encountered when using high-resolution electrophoresis and immunofixation. Annotation copyright by Book News, Inc., Portland, OR |
| high resolution electrophoresis: High-Resolution Electrophoresis and Immunofixation David F. Keren, 2013-10-22 High-Resolution Electrophoresis and Immunofixation: Techniques and Interpretation acquaints the reader with the available methodologies and instrumentation for performing high-resolution electrophoresis and immunofixation. This text presents the use of procedures of high-resolution electrophoresis and immunofixation to facilitate the diagnosis of a variety of serum protein abnormalities. It also provides case examples to illustrate the uses of these procedures and their possible caveats. The book contains chapters devoted to the methods and rationale for high-resolution electrophoresis; interpretation of high-resolution electrophoresis patterns in serum, urine, and cerebrospinal fluid; the immunofixation technique; and strategies for diagnosing monoclonal gammopathies. Medical technologists, physicians, and pathologists will find the book invaluable. |
| high resolution electrophoresis: Capillary Gel Electrophoresis Andras Guttman, László Hajba, 2021-12-04 Capillary Gel Electrophoresis and Related Microseparation Techniques covers all theoretical and practical aspects of capillary gel electrophoresis. It also provides an excellent overview of the key application areas of nucleic acid, protein and complex carbohydrate analysis, affinity-based methodologies, micropreparative aspects and related microseparation methods. It not only gives readers a better understanding of how to utilize this technology, but also provides insights into how to determine which method will provide the best technical solutions to particular problems. This book can also serve as a textbook for undergraduate and graduate courses in analytical chemistry, analytical biochemistry, molecular biology and biotechnology courses. - Covers all theoretical and practical aspects of capillary gel electrophoresis - Excellent overview of the key applications of nucleic acid, protein and complex carbohydrate analysis, affinity-based methodologies, micropreparative aspects and related microseparation methods - Teaches readers how to use the technology and select methods that are ideal for fundamental problems - Can serve as a textbook for undergraduate and graduate courses in analytical chemistry, analytical biochemistry, molecular biology and biotechnology courses |
| high resolution electrophoresis: Electrophoresis Milan, Bier, . ed, 1959 |
| high resolution electrophoresis: HIGH RESOLUTN ELECTROPHORESIS David F Keren, 1994-11-30 The second edition of this well-known explication of the techniques and interpretations of electrophoresis and immunofixation has been thoroughly updated. Incorporating the changes in technology since the first edition was published, the author has made extensive revisions, entirely replacing the section on immunoelectrophoresis with a discussion of the current technique of immunofixation. The majority of the original illustrations have been revised, and a new section on the interpretation of oligoclonal bans in cerebrospinal fluid has been included. |
| high resolution electrophoresis: Gel Electrophoresis Gilbert H. Mitchell, 2017 Polyacrylamide gel electrophoresis (PAGE) is performed routinely in research and diagnostics. The lack of internal standards, however, has been very disadvantageous for PAGE methodologies in comparison to alternative separation techniques like chromatography. Chapter one discusses how comparative fluorescence gel electrophoresis (CoFGE) has the potential to change this situation. Chapter Two focuses on elucidating the properties of polyacrylamide gel matrixes, discussing the essential principles of discontinuous PAGE in technology, and summarising the discontinuous buffer systems employed for the discontinuous PAGE in alkaline, neutral and acidic circumstances. Chapter Three discusses the need for the establishment of typical physiologic protein pattern for various avian patients. Chapter Four discusses constant field gel electrophoresis, a sensitive, rapid, economical and perspective method for detecting DNA double strand breaks and rejoining with high resolution. |
| high resolution electrophoresis: Bioanalytics Friedrich Lottspeich, Joachim W. Engels, 2018-05-29 Analytical methods are the essential enabling tools of the modern biosciences. This book presents a comprehensive introduction into these analytical methods, including their physical and chemical backgrounds, as well as a discussion of the strengths and weakness of each method. It covers all major techniques for the determination and experimental analysis of biological macromolecules, including proteins, carbohydrates, lipids and nucleic acids. The presentation includes frequent cross-references in order to highlight the many connections between different techniques. The book provides a bird's eye view of the entire subject and enables the reader to select the most appropriate method for any given bioanalytical challenge. This makes the book a handy resource for students and researchers in setting up and evaluating experimental research. The depth of the analysis and the comprehensive nature of the coverage mean that there is also a great deal of new material, even for experienced experimentalists. The following techniques are covered in detail: - Purification and determination of proteins - Measuring enzymatic activity - Microcalorimetry - Immunoassays, affinity chromatography and other immunological methods - Cross-linking, cleavage, and chemical modification of proteins - Light microscopy, electron microscopy and atomic force microscopy - Chromatographic and electrophoretic techniques - Protein sequence and composition analysis - Mass spectrometry methods - Measuring protein-protein interactions - Biosensors - NMR and EPR of biomolecules - Electron microscopy and X-ray structure analysis - Carbohydrate and lipid analysis - Analysis of posttranslational modifications - Isolation and determination of nucleic acids - DNA hybridization techniques - Polymerase chain reaction techniques - Protein sequence and composition analysis - DNA sequence and epigenetic modification analysis - Analysis of protein-nucleic acid interactions - Analysis of sequence data - Proteomics, metabolomics, peptidomics and toponomics - Chemical biology |
| high resolution electrophoresis: Image Analysis Donat P. Hader, 2000-08-23 Automatic image analysis has become an important tool in many fields of biology, medicine, and other sciences. Since the first edition of Image Analysis: Methods and Applications, the development of both software and hardware technology has undergone quantum leaps. For example, specific mathematical filters have been developed for quality enhanceme |
| high resolution electrophoresis: Protein Electrophoresis in Clinical Diagnosis David Keren, 2003-09-26 Since the publication of High-Resolution Electrophorsesis and Immunofixation 2e, there have been ever-increasing advances in the analyses of proteins, by electrophoresis in particular. Protein Electrophoresis in Clinical Diagnosis shows the changes in both techniques and interpretation, presenting a comprehensive review of serum protein techniques, |
| high resolution electrophoresis: Protein & Peptide Letters , 1994-07 |
| high resolution electrophoresis: Two-Dimensional Gel Electrophoresis of Proteins Julio Celis, 2012-12-02 Two-Dimensional Gel Electrophoresis of Proteins: Methods and Applications reviews current methods and clinical applications of two-dimensional gel electrophoresis of proteins, including the QUEST system, silver staining, and peptide mapping. Two-dimensional gel electrophoresis are applied to the study of diseases ranging from inborn errors of metabolism to human germ-line mutation rates, cancer, and mistranslation in animal and bacterial cells. This volume is organized into three sections encompassing 14 chapters and begins with an overview of the methodology of two-dimensional gel electrophoresis, followed by a discussion of computerized two-dimensional gel electrophoresis, silver staining, immunoblotting, and one- and two-dimensional peptide mapping. In most cases, a step-by-step guide to the techniques is given so that procedures may be easily repeated. A catalog of mouse fibroblast proteins is also given. The chapters that follow focus mainly on applications of two-dimensional gel electrophoresis in areas such as clinical and cancer research, human genetics, protein biosynthesis, and gene expression in plants. The final section presents current protein catalogs of Escherichia coli and human HeLa cells. This book is suitable for young researchers as well as for senior scientists working with a wide variety of problems in molecular and cell biology, basic biochemistry, genetics, and clinical research. |
| high resolution electrophoresis: Biophysical Chemistry of Proteins Engelbert Buxbaum, 2010-11-18 The book is structured in nine sections, each containing several chapters. The volume starts with an overview of analytical techniques and progresses through purification of proteins; protein modification and inactivation; protein size, shape, and structure; enzyme kinetics; protein-ligand interactions; industrial enzymology; and laboratory quality control. The book is targeted at all scientists interested in protein research. |
| high resolution electrophoresis: Electrophoretic Separation of Proteins Biji T. Kurien, R. Hal Scofield, |
| high resolution electrophoresis: Molecular Diagnostics E. van Pelt-Verkuil, W.B. van Leeuwen, R. te Witt, 2019-06-03 The books Molecular Diagnostics Part 1 and 2 provide a comprehensive and practical overview of the state-of-the-art molecular biological diagnostic strategies that are being used in a wide variety of disciplines. The editors and experts in their respective fields have combined their knowledge to write these two books. Many years of experience in the development, application and quality control of molecular diagnostic methods is reflected herewith. Molecular Diagnostics Part 1 is dedicated to the theoretical backgrounds of the technologies often applied in molecular diagnostics, in which nucleic acid amplification methods (such as real-time PCR), sequencing and bioinformatics are the basic tools. The assay design and -development, combined with items of trouble-shooting are described in detail. As a foundation of reliable molecular diagnostic assays, the quality control required for validation, implementation and performance of molecular diagnostic assays is thoroughly discussed. This book also provides extensive information for those working with molecular techniques in a wide variety of research applications using conventional and real-time PCR technology, Sanger and high throughput sequencing techniques, and bioinformatics. Molecular Diagnostics Part 2 highlights the applications of the molecular diagnostic methods in the various diagnostic laboratories, comprising: - Clinical microbiology - Clinical chemistry - Clinical genetics - Clinical pathology - Molecular hematopathology - Veterinary health - Plant health - Food safety Both full-colour and well-illustrated books are particularly valuable for students, clinicians, scientists and other professionals who are interested in (designing) molecular diagnostic methods and for those who wish to broaden their knowledge on the current molecular biological revolution. The information in the books highlights the trend of the integration of multiple (clinical) disciplines into one universal molecular laboratory. |
| high resolution electrophoresis: Electrophoretic Techniques Colin F. Simpson, Mary Whittaker, 1983 |
| high resolution electrophoresis: Protein Electrophoresis in Clinical Diagnosis David Keren, 2003-09-26 Since the publication of High-Resolution Electrophorsesis and Immunofixation 2e, there have been ever-increasing advances in the analyses of proteins, by electrophoresis in particular. Protein Electrophoresis in Clinical Diagnosis shows the changes in both techniques and interpretation, presenting a comprehensive review of serum protein techniques, immunofixation techniques, approaches to pattern interpretation, and pattern interpretation in both cerebralspinal fluid and urine. Conditions associated with Monoclunal Gammopathies are considered, as are the appropriate strategies for their detection. David Keren is well-known as the leader in this field, his work on guidelines becoming the benchmark for all those involved in protein detection in serum and urine. Dr Keren's book will be essential in every laboratory, and read by pathologists, chemical chemists, medical technicians and clinicians (particularly hematologists and oncologists). |
| high resolution electrophoresis: Techniques for High Resolution Electrophoresis Oak Ridge Technical Enterprises Corporation, 1973 |
| high resolution electrophoresis: Advances in Forensic Haemogenetics Walter Bär, Angelo Fiori, Umberto Rossi, 2012-12-06 th This volume comprises the Proceedings of the 15 Congress of the International Society of Forensic Haemogenetics (ISFH), held for the first time in Venezia Lido, th th Italy, on 13 -15 October 1993. The abstracts of the scientific contributions sent to the Congress have been sub divided into chapters with numbers and headings corresponding to the Congress sessions listed in the final programme. A general index of all authors, in alpha betical order, is given at the end of the book. The book consists of 188 contributions and addresses several problems presently being discussed in forensic haemogenetics. The main portion is, of course, devoted to DNA technology: present and future trends in DNA method ology, DNA polymorphisms in paternity testing and in criminal investigation, DNA sequencing, PCR methodology, quality control and quality assurance. Data have been accumulated on population genetics and biostatistics. A new look has been given at old friends, with important contributions on the molecular biology of classical markers. Conventional genetic markers have been studied. Problems connected with genetic typing and human rights have been dealt with in depth, and the history and geography of human genes have been elucidated. |
| high resolution electrophoresis: Physical Biochemistry David Sheehan, 2013-04-30 As will be seen, there is not much missing here. I thought that the sections were well balanced, with rarely too much or too little on a given topic...This is a text to be welcomed by both teachers and students. BIOCHEMISTRY & MOLECULAR BIOLOGY EDUCATION (on the first edition) The second edition of this successful textbook explains the basic principles behind the key techniques currently used in the modern biochemical laboratory and describes the pros and cons of each technique and compares one to another. It is non-mathematical, comprehensive and approachable for students who are not physical chemists. A major update of this comprehensive, accessible introduction to physical biochemistry. Includes two new chapters on proteomics and bioinformatics. Introduces experimental approaches with a minimum of mathematics and numerous practical examples. Provides a bibliography at the end of each chapter. Written by an author with many years teaching and research experience, this text is a must-have for students of biochemistry, biophysics, molecular and life sciences and food science. |
| high resolution electrophoresis: Cumulated Index Medicus , 1989 |
| high resolution electrophoresis: Multiple Myeloma and Related Serum Protein Disorders Neil S. Harris, MD, William E. Winter, 2012-03-23 A practical guide to the clinical use of serum and urine electrophoresis and also includes coverage of immunofixation electrophoresis. These techniques are essential in the accurate identification of monoclonal gammopathies and the diagnosis of multiple myeloma and related disorders. Interpretation is often challenging even for the experienced practitioner. Throughout the book the emphasis is on indications and practical aspects of interpreting test results. Particular attention is paid to differentiating false negative and false positive test results. The text provides clear, practical discussions extensively supported by representative images to guide the reader to accurate identification of specimens. |
| high resolution electrophoresis: Molecular Diagnostics George P. Patrinos, Wilhelm Ansorge, 2009-08-21 The 2e of Molecular Diagnostics, the only book dealing with diagnosis on a molecular level, discusses current molecular biological techniques used to identify the underlying molecular defects in inherited disease. The book delves further into the principle and brief description of the technique, followed by examples from the authors' own expertise. Contributors to the 2e are well-known experts in their field, and derive from a variety of disciplines, to ensure breadth and depth of coverage. Molecular Diagnostics, 2e , is a needed resource for graduate students, researchers, physicians and practicing scientists in molecular genetics and professionals from similar backgrounds working in diagnostic laboratories in academia or industry, as well as academic institutions and hospital libraries. - Deals exclusively with the currently used molecular biology techniques to identify the underlying molecular defect of inherited diseases - Includes pharmacogenetics and pharmacogenomics relating to new cancer therapies - Provies a comprehensive guide through emerging concepts and demonstrates how the available mutation screening technology can be implemented in diagnostic laboratories and provide better healthcare |
| high resolution electrophoresis: Immunology & Serology in Laboratory Medicine Mary Louise Turgeon, 2013-02-15 The 5th edition of this classic text sets the standard for comprehensive coverage of immunology. Building from a solid foundation of knowledge and skills, trusted author Mary Louise Turgeon takes you from basic immunologic mechanisms and serologic concepts to the theory behind the procedures you'll perform in the lab. Immunology & Serology in Laboratory Medicine, Fifth Edition is the go-to resource for everything from mastering automated techniques to understanding immunoassay instrumentation and disorders of infectious and immunologic origin. Packed with learning objectives, review questions, step-by-step procedures, and case studies, this text is your key to succeeding in today's modern laboratory environment. Full-color, six-page insert of photomicrographs provide a better picture of what you'll see in the laboratory. Learning objectives at the beginning of each chapter offer a measurable outcome you can achieve by completing the material. Chapter highlights at the end of each chapter provide a summary of the most important information covered in each chapter. Review questions at the end of each chapter are tied to learning objectives further enhance your understanding. Case studies challenge you to apply your knowledge and help strengthen your critical thinking skills. Glossary at the end of the book provides quick access to key terms and definitions. NEW! Expanded chapter on Vaccines as the importance of vaccines continues to become more evident. NEW! Updated chapter on Molecular Techniques incorporates the newest technology specific to immunology. NEW! Key terms at the beginning of each chapter help you learn the important vocabulary in immunology. NEW! Case studies with added multiple-choice questions in addition to critical thinking questions will help you apply your knowledge and develop critical-thinking skills. |
| high resolution electrophoresis: Research Methodology in Zoology P.S. Narayana, D. Varalakshmi, T. Pullaiah, K.R.S. Sambasiva Rao, 2018-03-01 The book comprises of different chapters associated with methodology in Zoology all at one place, describing in detail in a simple and comprehensive way. The importance of creativity and motivation in research, the planning and proposal of research project, the description of different techniques involved in animal research are described in an elaborate way. The book is also a source of different aspects of research methodology in animal science dealt with in a comprehensive manner tailored to the needs of postgraduate students/research scholars for easy understanding. The book is profusely illustrated. This book is intended for providing an overall understanding about the basics of research methodology associated with research, management of scientific information, and all about the communication of findings of research in Zoology. The book also serves as a good reference as well as a text book for PG students as well as research scholars in Animal Science working for their M.Phil. and Ph.D. for understanding the different facets of the process of scientific research. |
| high resolution electrophoresis: Methods in Virology Karl Maramorosch, Hilary Koprowski, 2014-06-28 Methods in Virology, Volume V focuses on the methods used in virology, including hybridization, gel electrophoresis, freeze-etching technique, and ultracentrifugation. The selection first offers information on the fusion of cells for virus studies and production of cell hybrids; approaches to ultracentrifugation; and polyacrylamide gel electrophoresis of viral RNA. Discussions focus on applications to virological problems and analysis of results; analysis of the distribution of RNA on polyacrylamide gels after electrophoresis; and biological analysis of DNA components. The book then examines the polyacrylamide gel electrophoresis of viral proteins, DNA-RNA and DNA-DNA hybridization in virus research, and techniques of RNA-DNA hybridization in solution for the study of viral transcription. Topics include preparation of nucleic acids, hybridization and elution procedures that minimize RNA degradation, and procedures for acrylamide gel electrophoresis. The text takes a look at freeze-etching technique for the study of virus ultrastructure; procedures to increase virus yield from infected plants; and the immunoperoxidase technique. Concerns include principles of the immunoperoxidase technique, histochemical detection of peroxidase activity, sequence of events in virus infection, and factors affecting virus yield. The selection is a valuable source of data for researchers interested in the methods employed in virology. |
| high resolution electrophoresis: Research Objective National Cancer Program Planning Conference, 1975 |
| high resolution electrophoresis: Immunology & Serology in Laboratory Medicine - E-Book Mary Louise Turgeon, 2013-02-15 The 5th edition of this classic text sets the standard for comprehensive coverage of immunology. Building from a solid foundation of knowledge and skills, trusted author Mary Louise Turgeon takes you from basic immunologic mechanisms and serologic concepts to the theory behind the procedures you’ll perform in the lab. Immunology & Serology in Laboratory Medicine, Fifth Edition is the go-to resource for everything from mastering automated techniques to understanding immunoassay instrumentation and disorders of infectious and immunologic origin. Packed with learning objectives, review questions, step-by-step procedures, and case studies, this text is your key to succeeding in today’s modern laboratory environment. Full-color, six-page insert of photomicrographs provide a better picture of what you’ll see in the laboratory. Learning objectives at the beginning of each chapter offer a measurable outcome you can achieve by completing the material. Chapter highlights at the end of each chapter provide a summary of the most important information covered in each chapter. Review questions at the end of each chapter are tied to learning objectives further enhance your understanding. Case studies challenge you to apply your knowledge and help strengthen your critical thinking skills. Glossary at the end of the book provides quick access to key terms and definitions. NEW! Expanded chapter on Vaccines as the importance of vaccines continues to become more evident. NEW! Updated chapter on Molecular Techniques incorporates the newest technology specific to immunology. NEW! Key terms at the beginning of each chapter help you learn the important vocabulary in immunology. NEW! Case studies with added multiple-choice questions in addition to critical thinking questions will help you apply your knowledge and develop critical-thinking skills. |
| high resolution electrophoresis: Mechanisms Of Gene Expression: Structure, Function And Evolution Of The Basal Transcriptional Machine Robert O J Weinzierl, 1999-08-10 A detailed knowledge of the mechanisms underlying the transcriptional control of gene expression is of fundamental importance to many areas of contemporary biomedical research, ranging from understanding basic issues (such as control of embryonic development) to practical applications in industry and medicine. Although elementary concepts of gene expression are described in all general molecular biology textbooks, the depth of coverage is often rather limited and recent discoveries are sometimes not adequately taken into consideration.This book presents much of the current thinking concerning molecular mechanisms of transcriptional control in a form easily accessible to undergraduates with an understanding of basic molecular biology concepts. It contains detailed information about the various pro- and eukaryotic transcriptional machineries that has recently become available through the combined efforts of geneticists, biochemists and structural biologists. The book will thus not only serve as an undergraduate text but also offer something new and interesting to more advanced readers and professional scientists who want to keep up to date with rapid advances in this field. |
| high resolution electrophoresis: Advances in Chromatography, Volume 47 Eli Grushka, Nelu Grinberg, 2009-02-23 For more than four decades, scientists and researchers have relied upon the Advances in Chromatography Series for the most up-to-date information on a wide range of developments in chromatographic methods and applications. Covering the state of the art in separation science, this volume continues to present timely, cutting-edge reviews on chromatog |
| high resolution electrophoresis: Proteins—Advances in Research and Application: 2012 Edition , 2012-12-26 Proteins—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Proteins. The editors have built Proteins—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Proteins in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Proteins—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
| high resolution electrophoresis: Animal Behavior Desk Reference Edward M. Barrows, 2000-12-28 Revised and updated, containing over 5,000 entries, with over 1,100 more entries than in the previous edition, Animal Behavior Desk Reference, Second Edition: A Dictionary of Behavior, Ecology, and Evolution provides definitions for terms in animal behavior, biogeography, evolution, ecology, genetics, psychology, statistics, systematics, and other |
| high resolution electrophoresis: BIOCHEMISTRY LABORATORY MANUAL PALLAB BASU, 2016-01-01 |
| high resolution electrophoresis: Proteomic and Metabolomic Approaches to Biomarker Discovery Haleem J. Issaq, Timothy D. Veenstra, 2019-10-24 Proteomic and Metabolomic Approaches to Biomarker Discovery, Second Edition covers techniques from both proteomics and metabolomics and includes all steps involved in biomarker discovery, from study design to study execution. The book describes methods and presents a standard operating procedure for sample selection, preparation and storage, as well as data analysis and modeling. This new standard effectively eliminates the differing methodologies used in studies and creates a unified approach. Readers will learn the advantages and disadvantages of the various techniques discussed, as well as potential difficulties inherent to all steps in the biomarker discovery process. This second edition has been fully updated and revised to address recent advances in MS and NMR instrumentation, high-field NMR, proteomics and metabolomics for biomarker validation, clinical assays of biomarkers and clinical MS and NMR, identifying microRNAs and autoantibodies as biomarkers, MRM-MS assay development, top-down MS, glycosylation-based serum biomarkers, cell surface proteins in biomarker discovery, lipodomics for cancer biomarker discovery, and strategies to design studies to identify predictive biomarkers in cancer research. - Addresses the full range of proteomic and metabolomic methods and technologies used for biomarker discovery and validation - Covers all steps involved in biomarker discovery, from study design to study execution - Serves as a vital resource for biochemists, biologists, analytical chemists, bioanalytical chemists, clinical and medical technicians, researchers in pharmaceuticals and graduate students |
| high resolution electrophoresis: Separation Methods In Proteomics Gary B. Smejkal, Alexander Lazarev, 2005-12-12 Driven by the widespread growth of proteomic practices, protein separation techniques have been refined to minimize variability, optimize particular applications, and adapt to user preferences in the analysis of proteins. Separation Methods in Proteomics provides a comprehensive examination of all major separation techniques for proteomic |
| high resolution electrophoresis: MicroRNA Methods John J. Rossi, 2007-08-30 MicroRNAs (miRNA) are tiny bits of genetic material that were unknown nearly 10 years ago but now represent an exciting field of study in biology. Upon their discovery, researchers revealed for the first time a new mechanism by which microRNA can stop the function of messenger RNA (mRNA) by literally cutting it in half, interfering with the normal function of specific messenger RNAs in gene expression. This expression of genes that code for essential proteins is essentially what controls whether a cell turns into a liver, lung, or brain cell, for example. Understanding what activates this process – or stops it – is a key to understanding the biological process and builds a foundation for advances in medicine and other fields. This volume in Methods in Enzymology presents valuable methods for studying MicroRNA, with three sections covering identification of MicroRNAs and their targets; MicroRNA expression, maturation and functional analysis; and MicroRNAs and disease. |
| high resolution electrophoresis: Photosynthesis G. Garab, 1998 Photosynthesis is a process on which virtually all life on Earth depends. To answer the basic questions at all levels of complexity, from molecules to ecosystems, and to establish correlations and interactions between these levels, photosynthesis research - perhaps more than any other discipline in biology - requires a multidisciplinary approach. Congresses probably provide the only forums where progress throughout the whole field can be overviewed. The Congress proceedings give faithful pictures of recent advances in photosynthesis research and outline trends and perspectives in all areas, ranging from molecular events to aspects of photosynthesis on the global scale. The Proceedings Book, a set of 4 (or 5) volumes, is traditionally highly recognized and intensely quoted in the literature, and is found on the shelves of most senior scientists in the field and in all major libraries. |
| high resolution electrophoresis: Photosynthesis: Mechanisms and Effects Gyözö Garab, 2012-12-06 Photosynthesis is a process on which virtually all life on Earth depends. To answer the basic questions at all levels of complexity, from molecules to ecosystems, and to establish correlations and interactions between these levels, photosynthesis research - perhaps more than any other discipline in biology - requires a multidisciplinary approach. Congresses probably provide the only forums where progress throughout the whole field can be overviewed. The Congress proceedings give faithful pictures of recent advances in photosynthesis research and outline trends and perspectives in all areas, ranging from molecular events to aspects of photosynthesis on the global scale. The Proceedings Book, a set of 4 (or 5) volumes, is traditionally highly recognized and intensely quoted in the literature, and is found on the shelves of most senior scientists in the field and in all major libraries. |
| high resolution electrophoresis: The Protein Protocols Handbook John M. Walker, 2002 The authors are commonly the techniques originators, and each has demonstrated a hands-on mastery of the methods described, always fine-tuning them here for optimal productivity. |
| high resolution electrophoresis: Issues in Pathology, Diagnostics, and Disease: 2011 Edition , 2012-01-09 Issues in Pathology, Diagnostics, and Disease: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Pathology, Diagnostics, and Disease. The editors have built Issues in Pathology, Diagnostics, and Disease: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Pathology, Diagnostics, and Disease in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Pathology, Diagnostics, and Disease: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
| high resolution electrophoresis: Ancient DNA Typing Susanne Hummel, 2013-03-09 This is the definitive source of information on techniques for the identification and sequencing of old DNA (pieces) and their use in biological and medical research and application. Application of aDNA techniques are useful tools for investigations reaching from evolutionary studies to law enforcement approaches. What brings them together is the interest in specific methods of handling aDNA, i.e. elaborated PCR and sequencing techniques and the interpretation of the results. This books serves as an ideal guideline for it demonstrates how problem-solving strategies can be applied in various areas. |
HIGH Definition & Meaning - Merriam-Webster
The meaning of HIGH is rising or extending upward a great distance : taller than average, usual, or expected. How to use high in a sentence. Synonym Discussion of High.
HIGH | definition in the Cambridge English Dictionary
HIGH meaning: 1. (especially of things that are not living) being a large distance from top to bottom or a long…. Learn more.
High - definition of high by The Free Dictionary
high - greater than normal in degree or intensity or amount; "a high temperature"; "a high price"; "the high point of his career"; "high risks"; "has high hopes"; "the river is high"; "he has a high …
HIGH Definition & Meaning | Dictionary.com
having a great or considerable extent or reach upward or vertically; lofty; tall. a high wall. having a specified extent upward. The apple tree is now 20 feet high. situated above the ground or …
HIGH definition and meaning | Collins English Dictionary
high is a general term, and denotes either extension upward or position at a considerable height: six feet high; a high shelf. lofty denotes imposing or even inspiring height: lofty crags. tall is …
What does HIGH mean? - Definitions.net
What does HIGH mean? This dictionary definitions page includes all the possible meanings, example usage and translations of the word HIGH. is much used in composition with variety of …
High: Definition, Meaning, and Examples - usdictionary.com
Feb 1, 2025 · As an adjective, "high" describes something positioned above average levels, whether literally (e.g., height) or figuratively (e.g., quality or value). When used as an adverb, …
HOME - Lebanon High School
Lebanon High School. 500 Blue Devil Blvd. Lebanon. TN. 37087. 615-444-9610. 615-443-1373. Links & Resources. Careers; Calendars; District Announcements; WilsonK12TN Mobile App; …
Meaning of high – Learner’s Dictionary - Cambridge Dictionary
HIGH definition: 1. having a large distance from the bottom to the top: 2. a large distance above the ground or the…. Learn more.
Examples of 'HIGH' in a Sentence - Merriam-Webster
Since the start of the pandemic in 2020, health care workers have been at a higher risk of contracting Covid. June, however, does come with cons: large crowds and high hotel rates. …
HIGH Definition & Meaning - Merriam-Webster
The meaning of HIGH is rising or extending upward a great distance : taller than average, usual, or expected. How to use high in a sentence. Synonym Discussion of High.
HIGH | definition in the Cambridge English Dictionary
HIGH meaning: 1. (especially of things that are not living) being a large distance from top to bottom or a long…. Learn more.
High - definition of high by The Free Dictionary
high - greater than normal in degree or intensity or amount; "a high temperature"; "a high price"; "the high point of his career"; "high risks"; "has high hopes"; "the river is high"; "he has a high …
HIGH Definition & Meaning | Dictionary.com
having a great or considerable extent or reach upward or vertically; lofty; tall. a high wall. having a specified extent upward. The apple tree is now 20 feet high. situated above the ground or some …
HIGH definition and meaning | Collins English Dictionary
high is a general term, and denotes either extension upward or position at a considerable height: six feet high; a high shelf. lofty denotes imposing or even inspiring height: lofty crags. tall is applied …
What does HIGH mean? - Definitions.net
What does HIGH mean? This dictionary definitions page includes all the possible meanings, example usage and translations of the word HIGH. is much used in composition with variety of meaning. …
High: Definition, Meaning, and Examples - usdictionary.com
Feb 1, 2025 · As an adjective, "high" describes something positioned above average levels, whether literally (e.g., height) or figuratively (e.g., quality or value). When used as an adverb, "high" …
HOME - Lebanon High School
Lebanon High School. 500 Blue Devil Blvd. Lebanon. TN. 37087. 615-444-9610. 615-443-1373. Links & Resources. Careers; Calendars; District Announcements; WilsonK12TN Mobile App; …
Meaning of high – Learner’s Dictionary - Cambridge Dictionary
HIGH definition: 1. having a large distance from the bottom to the top: 2. a large distance above the ground or the…. Learn more.
Examples of 'HIGH' in a Sentence - Merriam-Webster
Since the start of the pandemic in 2020, health care workers have been at a higher risk of contracting Covid. June, however, does come with cons: large crowds and high hotel rates. From …
