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| gene regulation a eukaryotic perspective david latchman: Gene Regulation David S. Latchman, 2002 This lucid, well structured and jargon-free book provides an up-to-date and comprehensive account of the processes involved in gene expression and the mechanisms by which such expression is regulated. New information on how viruses modify host gene regulation has been included in this new edition. Methods used to analyze gene expression have also been given more attention, with a new section added on methods for examining DNA binding by transcriptional factors. |
| gene regulation a eukaryotic perspective david latchman: Gene Control David Latchman, 2018-03-29 Gene Control offers a current description of how gene expression is controlled in eukaryotes, reviewing and summarizing the extensive primary literature into an easily accessible format. Gene Control is a comprehensively restructured and expanded edition of Latchman’s Gene Regulation: A Eukaryotic Perspective, Fifth Edition. The first part of the book deals with the fundamental processes of gene control at the levels of chromatin structure, transcription, and post-transcriptional processes. Three pairs of chapters deal with each of these aspects, first describing the basic process itself, followed by the manner in which it is involved in controlling gene expression. The second part of the book deals with the role of gene control in specific biological processes. Certain chapters deal with the importance of gene control in cellular signaling processes and for normal development of the embryo. Another chapter discusses the key roles played by gene-regulatory processes in the specification of differentiated cell types such as muscle cells and neurons. The final chapters discuss the consequences of errors in gene control; the relationship between gene misregulation and human diseases, especially cancer; and potential therapies designed specifically to target particular levels of gene control. Gene Control will be of value to students in biological sciences, as well as to scientists and clinicians interested in how genes are regulated in health and disease. |
| gene regulation a eukaryotic perspective david latchman: Gene Regulation : A Eukaryotic Perspective David S. Latchman, 1990-05-24 |
| gene regulation a eukaryotic perspective david latchman: Gene Regulation , 1997 |
| gene regulation a eukaryotic perspective david latchman: Gene Regulation David Latchman, 2007-01-25 Gene regulation is an essential process in the development and maintenance of a healthy body, and as such, is a central focus in both basic science and medical research. Gene Regulation, Fifth Edition provides the student and researcher with a clear, up-to-date description of gene regulation in eukaryotes, distilling the vast and complex primary literature into a concise overview. |
| gene regulation a eukaryotic perspective david latchman: National Library of Medicine Current Catalog National Library of Medicine (U.S.), 1991 |
| gene regulation a eukaryotic perspective david latchman: Eukaryotic Transcription Factors David S. Latchman, 2010-07-28 Transcription, or the process by which DNA produces RNA, is a central aspect of gene expression. Transcription factors regulate transcription during development and in disease states. As such, it is critical for researchers to gain a good understanding of the relationship between the structure of various families of transcription factors and their function, as well as roles in human disease. Since publication of the Fourth Edition, there have been major advances, notably in the areas of chromatin remodeling and genome-scale analyses. This complete update includes all new coverage of the latest developments, from enabling genomic technologies to studies on the importance of post-translational modifications beyond phosphorylation events. - Potential of transcription factors as therapeutic targets in human disease - Importance of histone modifications - Use of genome-based sequence analysis and high-throughput methods - Applications of the chromatin immunoprecipitation (ChIP) assay - Transcriptional elongation - Regulation by post-translational modifications - Regulatory networks and bioinformatics |
| gene regulation a eukaryotic perspective david latchman: Gene Regulation David Latchman, 2007-01-24 Gene regulation is an essential process in the development and maintenance of a healthy body, and as such, is a central focus in both basic science and medical research. Gene Regulation, Fifth Edition provides the student and researcher with a clear, up-to-date description of gene regulation in eukaryotes, distilling the vast and complex primary literature into a concise overview. |
| gene regulation a eukaryotic perspective david latchman: Gene Control, Second Edition David Latchman, 2015-02-20 The new edition of Gene Control has been updated to include significant advances in the roles of the epigenome and regulatory RNAs in gene regulation. The chapter structure remains the same: the first part consists of pairs of chapters that explain the mechanisms involved and how they regulate gene expression, and the second part deals with specific biological processes (including diseases) and how they are controlled by genes. Coverage of methodology has been strengthened by the inclusion more explanation and diagrams.The significant revision and updating will allow Gene Control to continue to be of value to students, scientists and clinicians interested in the topic of gene control. |
| gene regulation a eukaryotic perspective david latchman: Current Catalog National Library of Medicine (U.S.), 1993 First multi-year cumulation covers six years: 1965-70. |
| gene regulation a eukaryotic perspective david latchman: Molecular and Cellular Genetics Edward Bittar, 1996-09-24 The tools of molecular biology have revolutionised our understanding of gene structure and function and changed the teaching of genetics in a fundamental way. The transition from classical genetics to molecular genetics was initiated by two discoveries. One was the discovery that DNA has a complementary double helix structure and the other that a universal genetic code does exist. Both led to the acceptance of the central dogma that RNA molecules are made on DNA templates. The last twenty years have seen remarkable growth in our knowledge of molecular genetics, most of which is the outcome of recombinant DNA technology. This technology which is not limited to cloning, sequencing, and expression has created a biotechnology industry of its own, the purpose of which is to develop new diagnostic and therapeutic approaches in medicine. Both industries in collaboration with the biomedical community are now engaged in laying down the foundation of molecular medicine. The present volume seeks to provide a coherent account of the new science of molecular genetics. Its content however is by no means exhaustive, partly because of the publication explosion but more because of space restrictions. A rudimentary knowledge of genetics on the reader's part is assumed. Quite understandably, considerable emphasis is placed on major technical advances but not without expounding numerous new ideas and phenomena including alternative splicing, POR, DNA methylation, genomic imprinting, and so on. |
| gene regulation a eukaryotic perspective david latchman: The Bibliographic Index , 2005 |
| gene regulation a eukaryotic perspective david latchman: Methods for Human History Patrick Manning, 2020-09-28 This book presents a concise yet comprehensive survey of methods used in the expanding studies of human evolution, paying particular attention to new work on social evolution. The first part of the book presents principal methods for the study of biological, cultural, and social evolution, plus migration, group behavior, institutions, politics, and environment. The second part provides a chronological and analytical account of the development of these methods from 1850 to the present, showing how multidisciplinary rose to link physical, biological, ecological, and social sciences. The work is especially relevant for readers in history and social sciences but will be of interest to readers in biological and ecological fields who are interested in exploring a wide range of evolutionary studies. |
| gene regulation a eukaryotic perspective david latchman: Landmarks in Gene Regulation David S. Latchman, 1997 Twenty years ago there was no known example in eukaryotes of a defined regulatory protein which bound to a specific DNA sequence in a target gene and regulated its expression. Since then a large number of such regulatory proteins, or transcription factors, have been defined and their roles in regulating the expression of specific genes analyzed. |
| gene regulation a eukaryotic perspective david latchman: Bibliographic Index , 2006 |
| gene regulation a eukaryotic perspective david latchman: Genetic Counseling , 1995 |
| gene regulation a eukaryotic perspective david latchman: The Botanica , 1996 |
| gene regulation a eukaryotic perspective david latchman: The British National Bibliography Arthur James Wells, 2000 |
| gene regulation a eukaryotic perspective david latchman: Gene Control David S. Latchman, Venugopalan Cheriyath, 2025-02-26 The new edition of Gene Control, for the first time, provides extensive coverage on prokaryotic gene regulation, which makes it the only textbook offering a complete and detailed account of gene control for both prokaryotic and eukaryotic organisms. The core objective of this edition is to educate students about the fundamental principles and mechanisms governing gene expression, regulation, and function. To reinforce these ideas, each chapter now includes discussion questions to promote critical thinking. There are also multiple choice questions and animations for students, and a large question bank and figure slides for instructors. The textbook also emphasizes the vital role of scientific experiments and evidence in shaping our current understanding of gene control and provides comprehensive coverage of essential gene expression techniques and methodologies throughout the book. This extensively updated edition of the renowned textbook Gene Control will remain a valuable resource for students, instructors, researchers, and medical professionals exploring various aspects of gene control, ranging from the regulation of genes in infectious diseases to embryonic development across different organisms, from bacteria to humans. |
| gene regulation a eukaryotic perspective david latchman: General Program, Annual AIBS Meeting of Biological Societies American Institute of Biological Sciences, 1990 |
| gene regulation a eukaryotic perspective david latchman: Paperbound Books in Print , 1992 |
| gene regulation a eukaryotic perspective david latchman: Paperbound Books in Print 1995 Reed Reference Publishing, R5ference Reed, 1995-12 |
| gene regulation a eukaryotic perspective david latchman: Subject Guide to Books in Print , 1971 |
| gene regulation a eukaryotic perspective david latchman: Computational Biomedicine Peter Coveney, Vanessa Díaz-Zuccarini, Peter Hunter, Marco Viceconti, 2014-06 Computational Biomedicine unifies the different strands of a broad-ranging subject to demonstrate the power of a tool that has the potential to revolutionise our understanding of the human body, and the therapeutic strategies available to maintain and protect it. |
| gene regulation a eukaryotic perspective david latchman: General Biology Lab Manual Russell Skavaril, Mary Finnen, Steven Lawton, 1993 This laboratory manual, suitable for biology majors or non-majors, provides a selection of lucid, comprehensive experiments that include excellent detail, illustration, and pedagogy. |
| gene regulation a eukaryotic perspective david latchman: The Zoological Record , 2002 |
| gene regulation a eukaryotic perspective david latchman: American Book Publishing Record , 1990 |
| gene regulation a eukaryotic perspective david latchman: التطور: ما تزال نظرية في أزمة د. مايكل دنتون, يقول دنتون عن كتابه السابق أن هدفه الأساسي فيه كان إثبات أنّ الطبيعة غير مستمرة في الأساس، أي أن الحياة ليست نتيجة للتطور التدريجي البطيء. ولا شك أن هذا يسقط الفكرة الداروينية تماما، أما كتابه الجديد، فيأتي بعد تخليه عن مفهوم التكيفية وتبنيه للبنيوية في عالم الأحياء، لأسباب كثيرة، يفيض في شرحها داخل هذا الكتاب. تأثير ذلك على الصراع مع الداروينية خطير. فنحن إن تجاوزنا النقاش حول كافة الادعاءات التي تفترضها الداروينية، فلا شك أنه لا يمكن نزع فكرة أن كل خطوة تطورية يخطوها أي كائن، هدفها كان التكيف، ولكن ماذا لو أثبتت الأدلة العلمية خطأ تلك الفكرة؟ في إطار البنيوية، لم تظهر الحياة والتنوع الهائل فيها بعامل الصدف وطول الزمن، بل هي وجدت كما هي في الطبيعة لغرض ما، وهنا يتوقف العلم التجريبي وينتقل الحديث للمجال الفلسفي أو الديني، والذي لا شك أنه سيرى أطروحة دنتون كإثبات على افتقار الحياة لوجود الخالق. لم يتوقف دنتون عن مراجعة حججه التي أوردها سابقا وتجديدها، أو عند حتى تقديم البنيوية، بل انتقل في إطار رؤيته الشاملة للبنيوية، للحديث عن تلك المنطقة المثيرة؛ الإنسان. ذلك النوع المميز الذي له قدرات لا يمكن تفسيرها إطلاقا بالتكيف والوظيفة والتطور التدريجي البطيء... وغيرها من العبث الدارويني. كل ما سبق، يؤكد على الفشل التام للبارادايم التطوري، وأنه آن الأوان للعلماء أن يعطوا نظرية (التصميم الذكي) الفرصة كإطار للبحث في علم الحياة، تماما كما فعل دنتون. |
| gene regulation a eukaryotic perspective david latchman: Genetics and Genomics in Medicine T. Strachan, 2015 |
| gene regulation a eukaryotic perspective david latchman: Principles of Molecular Virology Alan Cann, 2005-07-26 Principles of Molecular Virology, Fourth Edition provides an essential introduction to modern virology in a clear and concise manner. It is a highly enjoyable and readable text with numerous illustrations that enhance the reader's understanding of important principles. It contains new material on virus structure, virus evolution, zoonoses, bushmeat, SARS and bioterrorism. The standard version includes a CD-ROM with Flash animations, virtual interactive tutorials and experiments, self-assessment questions, useful online resources, along with the glossary, classification of subcellular infectious agents and history of virology. |
| gene regulation a eukaryotic perspective david latchman: Gene regualation David S. Latchman, 1998 |
| gene regulation a eukaryotic perspective david latchman: The Culture of Extinction Frederic L. Bender, 2003 No Marketing Blurb |
| gene regulation a eukaryotic perspective david latchman: Heredity , 1947 |
| gene regulation a eukaryotic perspective david latchman: Forthcoming Books Rose Arny, 2002 |
| gene regulation a eukaryotic perspective david latchman: Recent Advances in Glucocorticoid Receptor Action A. Cato, H. Schaecke, K. Asadullah, 2013-04-17 The long-term use of glucocorticoids is associated with several deleterious effects. Attempts to separate the beneficial from the adverse effects of these compounds have met with varying degrees of difficulty. The discovery of distinct modes of action of the glucocorticoid receptor, the protein that mediates glucocorticoid action has opened up many possibilities for improving glucocorticoid therapy. This book provides an in-depth overview of the molecular actions of the glucocorticoid receptor and discusses the chances of an imminent identification of selective glucocorticoid agonists. Such componds should fulfill all the criteria of a glucocorticoid but should lack the sideeffects so far linked with classical glucocorticoids. |
| gene regulation a eukaryotic perspective david latchman: Cell Biology Stephen R. Bolsover, Jeremy S. Hyams, Elizabeth A. Shephard, Hugh A. White, Claudia G. Wiedemann, 2004-02-15 This text tells the story of cells as the unit of life in a colorful and student-friendly manner, taking an essentials only approach. By using the successful model of previously published Short Courses, this text succeeds in conveying the key points without overburdening readers with secondary information. The authors (all active researchers and educators) skillfully present concepts by illustrating them with clear diagrams and examples from current research. Special boxed sections focus on the importance of cell biology in medicine and industry today. This text is a completely revised, reorganized, and enhanced revision of From Genes to Cells. |
| gene regulation a eukaryotic perspective david latchman: The Pancreas John A. Williams, Fred S. Gorelick, 2021 This book provides comprehensive and definitive coverage of the current understanding of the structure and function of the exocrine pancreas. While emphasis is on normal physiology, the relevant cell biological, developmental and biochemical information is also provided. Where appropriate, chapters also include material on functional changes in pancreatitis. All chapters are fully referenced and provide up to date information. The book has been overseen and published by the American Pancreatic Association with Fred S. Gorelick and John A. Williams as Editors. It includes 26 chapters written by an international group of authorities; completed chapters are also presented in open access format on the Pancreapedia (www.pancreapedia.org). The book contains full-color images and summary diagrams that enhance readability and extend the detail provided in the text. The Pancreas: Biology and Physiology is divided into four sections: Pancreatic Exocrine Structure and Function Anatomy, Bioenergetics, Cytoskeleton, Intracellular Signaling Acinar Cells Digestive enzyme synthesis, intracellular transport, Zymogen granules, Exocytosis Exocrine Pancreas Integrative Responses Hormonal and Neural Control of Protein and Fluid Secretion, Molecular mechanisms of fluid and bicarbonate secretion, regulation of growth and regeneration Pancreatic Islet and Stellate Cell Structure and Function Structure and vasculature of islets, regulation of islet secretion, Stellate Cells in health and disease The book is designed to be a reference book for pancreas researchers but its clear and readable text will appeal to teachers, students and all individuals interested in the exocrine pancreas. |
| gene regulation a eukaryotic perspective david latchman: Molecular Driving Forces Ken Dill, Sarina Bromberg, 2010-10-21 Molecular Driving Forces, Second Edition E-book is an introductory statistical thermodynamics text that describes the principles and forces that drive chemical and biological processes. It demonstrates how the complex behaviors of molecules can result from a few simple physical processes, and how simple models provide surprisingly accurate insights into the workings of the molecular world. Widely adopted in its First Edition, Molecular Driving Forces is regarded by teachers and students as an accessible textbook that illuminates underlying principles and concepts. The Second Edition includes two brand new chapters: (1) Microscopic Dynamics introduces single molecule experiments; and (2) Molecular Machines considers how nanoscale machines and engines work. The Logic of Thermodynamics has been expanded to its own chapter and now covers heat, work, processes, pathways, and cycles. New practical applications, examples, and end-of-chapter questions are integrated throughout the revised and updated text, exploring topics in biology, environmental and energy science, and nanotechnology. Written in a clear and reader-friendly style, the book provides an excellent introduction to the subject for novices while remaining a valuable resource for experts. |
| gene regulation a eukaryotic perspective david latchman: The Betrayal of Marx , 1975 |
| gene regulation a eukaryotic perspective david latchman: Ovarian Cancer George Coukos, Andrew Berchuck, Robert Ozols, 2008-06-06 Aegean Conferences is an independent, nonprofit, educational organization directed and managed by the scientific community. The board is made up of nine researchers/scientists in various disciplines from Harvard, Brown, University of Pennsylvania, UCSD, Princeton, Biovista and the Foundation for Biomedical Research Academy of Athens. The board both invites and approves unsolicited proposals for Conferences in all fields of Science, Engineering, Arts, and Humanities. The purpose of the Conferences is to bring together individuals with common interests to examine the emerging and most advanced aspects of their particular field. The Symposium on Ovarian Cancer: State of the Art and Future Directions intends to bring together international experts interested in the development of novel diagnostic, prognostic and therapeutic tools for ovarian cancer. The meeting will function as a think tank where clinicians, translational and basic scientists, and parties from the biotechnology and pharmaceutical industry will get together to review recent advances in clinical research and translational science in ovarian cancer and define areas of future research opportunities and priorities. |
GeneCards - Human Genes | Gene Database | Gene Search
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Powerful Gene Set Analysis | GeneAnalytics - Your Gene Set, In …
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BRCA1 Gene - GeneCards | BRCA1 Protein | BRCA1 Antibody
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Mar 30, 2025 · This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages.
TGFB1 Gene - GeneCards | TGFB1 Protein | TGFB1 Antibody
Mar 30, 2025 · Complete information for TGFB1 gene (Protein Coding), Transforming Growth Factor Beta 1, including: function, proteins, disorders, pathways, orthologs, and expression.
GeneAnalytics™ - Powerful Gene Set Analysis - GeneAnalytics
GeneAnalytics™ – GeneAnalytics supports analysis of gene sets with multiple genes, and enables matching of gene sets to tissues and cells within LifeMap Discovery.
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Mar 30, 2025 · Complete information for VEGFA gene (Protein Coding), Vascular Endothelial Growth Factor A, including: function, proteins, disorders, pathways, orthologs, and expression.
TP53 Gene - GeneCards | P53 Protein | P53 Antibody
Mar 30, 2025 · This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular …
GeneCards - Human Genes | Gene Database | Gene Search
Mar 28, 2025 · GeneCards is a searchable, integrative database that provides comprehensive, user-friendly information on all annotated and predicted human genes. The …
Powerful Gene Set Analysis | GeneAnalytics - Your Gene Set…
GeneAnalytics enables researchers to identify compounds related to their gene sets, and further link to biochemical and pharmacological information about drugs, small …
BRCA1 Gene - GeneCards | BRCA1 Protein | BRCA1 Antib…
Mar 28, 2025 · The BRCA1 gene contains 22 exons spanning about 110 kb of DNA. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal …
CTNNB1 Gene - GeneCards | CTNB1 Protein | CTNB1 Antib…
Mar 28, 2025 · Complete information for CTNNB1 gene (Protein Coding), Catenin Beta 1, including: function, proteins, disorders, pathways, orthologs, and expression. …
TNF Gene - GeneCards | TNFA Protein | TNFA Antibody
Mar 30, 2025 · This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by …
