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| epilepsy a comprehensive textbook volume 1: Oxford Textbook of Epilepsy and Epileptic Seizures Simon Shorvon, Renzo Guerrini, Mark Cook, Samden Lhatoo, 2012-12-20 Epilepsy is the most common serious neurological condition, affecting children and adults, and can occur in a variety of medical settings. It has many causes and many forms, and a variable prognosis. Mortality and morbidity are high, social and legal consequences can stretch well beyond the purely medical, and its management is often poor. Part of the Oxford Textbooks in Clinical Neurology (OTCN) series, this volume covers the scientific basis, clinical diagnosis, and treatment of epilepsy and epileptic seizures. Written by internationally-renowned specialists, each chapter comprehensively covers the current knowledge and evidence base related to each aspect of the disorder, with an emphasis on the personal experience of the authors. The print edition of the Oxford Textbook of Epilepsy and Epileptic Seizures is complemented by an online version, which allows access to the full content of the textbook, contains links from the references to primary research journal articles, enables full text searches, and provides access to figures and tables that can be downloaded to PowerPoint?. This textbook will prove a useful clinical reference for neurologists and senior trainees in neurology, an educational manual for trainees, and will offer practical assistance to all physicians advising people with epilepsy. |
| epilepsy a comprehensive textbook volume 1: The Comprehensive Evaluation and Treatment of Epilepsy Steven C. Schachter, Donald L. Schomer, 1997-05-22 Epilepsy is, after headache, the second most common neurological disorder. This book clarifies the many courses of action to take in treating patients with epilepsy. It presents current knowledge about seizures and epilepsy in a comprehensive, socially conscious, and clear manner. The editors have provided this information in a comprehensive, easy-to-use, and practical form. This short, simple pedagogical guide to the diagnosis and management of epilepsy is an important reference work for all medical schools, hospitals, clinics, and primary care centers. - This book integrates the latest research into essential reviews on: - Initial management of patients with seizures - Neuroradiological evaluation of epilepsy - Psychosocial aspects of epilepsy - Neuropsychologic problems associated with epilepsy - Psychiatric disorders - Diagnosis and treatment of status epilepticus - Nonepileptic seizures - Ambulatory EEG monitoring - Epilepsy surgery - Endocrine aspects of partial seizures - Epilepsy in the elderly |
| epilepsy a comprehensive textbook volume 1: Astrocytes and Epilepsy Jacqueline A. Hubbard, Devin K. Binder, 2016-07-05 Epilepsy is a devastating group of neurological disorders characterized by periodic and unpredictable seizure activity in the brain. There is a critical need for new drugs and approaches given than at least one-third of all epilepsy patients are not made free of seizures by existing medications and become medically refractory. Much of epilepsy research has focused on neuronal therapeutic targets, but current antiepileptic drugs often cause severe cognitive, developmental, and behavioral side effects. Recent findings indicate a critical contribution of astrocytes, star-shaped glial cells in the brain, to neuronal and network excitability and seizure activity. Furthermore, many important cellular and molecular changes occur in astrocytes in epileptic tissue in both humans and animal models of epilepsy. The goal of Astrocytes and Epilepsy is to comprehensively review exciting findings linking changes in astrocytes to functional changes responsible for epilepsy for the first time in book format. These insights into astrocyte contribution to seizure susceptibility indicate that astrocytes may represent an important new therapeutic target in the control of epilepsy. Astrocytes and Epilepsy includes background explanatory text on astrocyte morphology and physiology, epilepsy models and syndromes, and evidence from both human tissue studies and animal models linking functional changes in astrocytes to epilepsy. Beautifully labelled diagrams are presented and relevant figures from the literature are reproduced to elucidate key findings and concepts in this rapidly emerging field. Astrocytes and Epilepsy is written for neuroscientists, epilepsy researchers, astrocyte investigators as well as neurologists and other specialists caring for patients with epilepsy. - Presents the first comprehensive book to synthesize historical and recent research on astrocytes and epilepsy into one coherent volume - Provides a great resource on the field of astrocyte biology and astrocyte-neuron interactions - Details potential therapeutic targets, including chapters on gap junctions, water and potassium channels, glutamate and adenosine metabolism, and inflammation |
| epilepsy a comprehensive textbook volume 1: Seizures and Epilepsy Jerome Engel, 2013-01-31 This second edition of 'Seizures and Epilepsy' is completely revised, due to tremendous advances in the understanding of the fundamental neuronal mechanisms underlying epileptic phenomena, as well as current diagnosis and treatment, which have been heavily influenced over the past several decades by seminal neuroscientific developments, particularly the introduction of molecular neurobiology, genetics, and modern neuroimaging. This resource covers a broad range of both basic and clinical epileptology. |
| epilepsy a comprehensive textbook volume 1: Epilepsy Jerome Engel, Timothy A. Pedley, Jean Aicardi, 2007-09-28 Written and edited by world-renowned authorities, this three-volume work is, to quote a reviewer, the definitive textbook about seizures and epilepsy. This Second Edition is thoroughly updated and gives you a complete print and multimedia package: the three-volume set plus access to an integrated content Website. More than 300 chapters cover the spectrum of biology, physiology, and clinical information, from molecular biology to public health concerns in developing countries. Included are detailed discussions of seizure types and epilepsy syndromes; relationships between physiology and clinical events; psychiatric and medical comorbidity; conditions that could be mistaken for epilepsy; and an increasing range of pharmacologic, surgical, and alternative therapies, including vagus nerve stimulation and deep brain stimulation. This edition describes many new antiepileptic drugs, major advances in surgical treatment, and state-of-the-art neuroimaging, EEG, and other technologies for diagnosis and seizure prediction. A companion Website offers instant access to the complete, fully searchable text, plus an image bank of additional figures, video footage, and annual updates to selected chapters. |
| epilepsy a comprehensive textbook volume 1: Textbook of Epilepsy Surgery Hans O. Luders, 2008-07-11 Textbook of Epilepsy Surgery covers all of the latest advances in the surgical management of epilepsy. The book provides a thorough understanding of epileptogenic mechanisms in etiologically different types of epilepsy and explains neuronavigation systems. It discusses new neuroimaging techniques, new surgical strategies, and more aggressive surgical approaches in cases with catastrophic epilepsies. The contributors also analyze the improved statistics of surgical outcome in different epilepsy types. The book follows a systematic approach to the diagnostic evaluation of patients who are candidates for epilepsy surgery. It first discusses the general principles of surgery, and then describes the presurgical evaluation according to the six zones (symptomatogenic, irritative, ictal onset, epileptic lesion, functional deficit, and epileptogenic zone). This series of chapters concludes with the description of the Epilepsy Surgery Management Meeting, an essential and indispensable part of the surgical evaluation. The book next incorporates detailed discussions of the cortical mapping techniques and the numerous surgical techniques. This is followed by the post-surgical medical management and a discussion of the surgical outcome. Finally, selected case studies are presented, along with protocols for the storage and processing of brain tissue for molecular studies. This definitive textbook is an invaluable reference for neurologists, neurosurgeons, epilepsy specialists, and those interested in epilepsy and its surgical treatment. |
| epilepsy a comprehensive textbook volume 1: Epilepsy: A Comprehensive Textbook Jerome Engel Jr, Solomon L. Moshé, 2023-10-23 Authoritative and updated, Epilepsy: A Comprehensive Textbook, 3rd Edition, contains 365 chapters that cover the full spectrum of relevant topics in biology, physiology, and clinical information, from molecular biology to public health concerns in developing countries. Written by world-renowned authorities and expertly edited by epileptologists Drs. Jerome Engel, Jr., Solomon L. Moshé, Aristea S. Galanopoulou, John M. Stern, Alexis Arzimanoglou, Jacqueline A. French, Renzo Guerrini, Andres M. Kanner, and Istvan Mody, this three-volume work includes detailed discussions of seizure types and epilepsy syndromes, relationships between physiology and clinical events, psychiatric and medical comorbidities, conditions that could be mistaken for epilepsy, and an increasing range of pharmacologic, surgical, and alternative therapies. |
| epilepsy a comprehensive textbook volume 1: Models of Seizures and Epilepsy Asla Pitkänen, Paul Buckmaster DVM PhD, Aristea S Galanopoulou, Solomon L. Moshé, 2017-06-14 Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of epilepsy, and novel technologies to study seizures and epilepsies in animals. - Provides a comprehensive reference detailing animal models of epilepsy and seizure - Offers insights on the use of novel technologies that can be applied in experimental epilepsy research - Edited by leading experts in the field that provide not only technical reviews of these models but also conceptual critiques - Comments on the strengths and limitations of various models, including their relationship to clinical phenomenology and their value in developing better understanding and treatments |
| epilepsy a comprehensive textbook volume 1: The Treatment of Epilepsy Simon Shorvon, Emilio Perucca, Jerome Engel, Jr., 2015-09-15 Highly Commended at the British Medical Association Book Awards 2016 The Treatment of Epilepsy, fourth edition, is a comprehensive reference and clinical guide to the pharmacological, medical and surgical options available in the treatment of epilepsy. The text is compiled by a group of internationally renowned editors and contributors and is now in full color and extensively illustrated The first two sections cover the background to, and principles of, treatment in different clinical situations Section three comprises a series of systematic reviews of contemporary drug therapy, devoting one chapter to each anti-epileptic drug and covering all clinically-relevant aspects Section four focuses on the surgical options, devoting individual chapters to each of the modalities of presurgical assessment and to each surgical operation or approach This 4th edition is extensively revised incorporating the many recent developments in therapy, and comprises 81 chapters from world experts from 18 countries |
| epilepsy a comprehensive textbook volume 1: Navigating Life with Epilepsy David C. Spencer, 2016-09-01 Roughly 3 million people in the United States have already been diagnosed with epilepsy and another 200,000 new cases are diagnosed each year. Worldwide, approximately 1 percent of the global population is diagnosed with epilepsy at some point in their lives. With the diagnosis come questions, concerns, and uncertainties from both the person diagnosed and their family. So, where to go? Navigating Life with Epilepsy provides accessible, comprehensive, and up-to-date information about epilepsy shared from the two decades of experience of epileptologist David Spencer, MD, FAAN. This book guides the reader through the initial diagnosis, offers explanations on current approaches to diagnostic testing, medications, treatment options, and life management for the patient, their family, and their caregiver. Patient's stories are peppered throughout to illustrate that you are not alone: like you, they must navigate the myriad psychosocial challenges associated with epilepsy, including everyday concerns like driving, work, and relationships. Navigating Life with Epilepsy is a perfect resource for both patients with epilepsy and the family members and friends who care for them. |
| epilepsy a comprehensive textbook volume 1: Advanced Therapy in Epilepsy James W. Wheless, James Willmore, Roger A. Brumback, 2009 A comprehensive and up-to-date primer on the latest therapeutic advances in the management and treatment of epilepsy, this work includes practical information on diagnostic criteria for all different syndromes along with detailed discussions of appropriate agents. |
| epilepsy a comprehensive textbook volume 1: A Clinical Guide to Epileptic Syndromes and their Treatment C. P. Panayiotopoulos, 2007-07-30 Affecting 4 percent of children and 1-2 percent of the general population, epilepsy is one of the most common neurological disorders. The 1st edition of this guide proved to be the only one of its kind, covering many important aspects of diagnosis and treatment. Due to the continued advances being made in the subject, and building on the sell-out success of the 1st edition this thorough revision reflects the latest report of the ILAE classification core group and the significant progress made in the diagnosis, classification and treatment of the epilepsies. |
| epilepsy a comprehensive textbook volume 1: Ions in the Brain George G. Somjen, 2004 Ions, their movements across membranes, and their flow through specialized ion channels are central to the understanding of brain function, normal and pathological. This book deals with the regulation of ions in brain, and the effects of changing ion levels on the excitability of neurons and on synaptic transmission. The roles of ions in generating epileptic seizures are considered, as well as in the devastation caused by hypoxia and stroke in brain tissue. |
| epilepsy a comprehensive textbook volume 1: Absolute Epilepsy and EEG Rotation Review Mona Sazgar, Michael G. Young, 2019-03-01 This book contains the most essential information needed for an epilepsy/ EEG rotation. Chapters are formatted with bullet points and feature clinical pearls. Concise and easy-to-read, this quick reference provides neurology residents, clinical neurophysiology and epilepsy fellows, and other clinicians with the most critical information in epilepsy and EEG in a simplified, yet comprehensive format. Divided into two sections, the book first covers the diagnosis, characteristics, and treatment of epilepsy. The second section focuses on EEG placement, procedures, and patterns in various neurological disorders. |
| epilepsy a comprehensive textbook volume 1: The Comorbidities of Epilepsy Marco Mula, 2019-04-20 Epilepsy is one of most frequent neurological disorders affecting about 50 million people worldwide and 50% of them have at least another medical problem in comorbidity; sometimes this is a the cause of the epilepsy itself or it is due to shared neurobiological links between epilepsy and other medical conditions; other times it is a long-term consequence of the antiepileptic drug treatment. The Comorbidities of Epilepsy offers an up-to-date, comprehensive overview of all comorbidities of epilepsy (somatic, neurological and behavioral), by international authorities in the field of clinical epileptology, with an emphasis on epidemiology, pathophysiology, diagnosis and management. This book includes also a critical appraisal of the methodological aspects and limitations of current research on this field. Pharmacological issues in the management of comorbidities are discussed, providing information on drug dosages, side effects and interactions, in order to enable the reader to manage these patients safely. The Comorbidities of Epilepsy is aimed at all health professionals dealing with people with epilepsy including neurologists, epileptologists, psychiatrists, clinical psychologists, epilepsy specialist nurses and clinical researchers. - Provides a comprehensive overview of somatic, neurological and behavioral co-morbidities of epilepsy - Discusses up-to-date management of comorbidities of epilepsy - Written by a group of international experts in the field |
| epilepsy a comprehensive textbook volume 1: Textbook of Epilepsy Surgery Hans O. Luders, 2008-07-11 Textbook of Epilepsy Surgery covers all of the latest advances in the surgical management of epilepsy. The book provides a better understanding of epileptogenic mechanisms in etiologically different types of epilepsy and explains neuronavigation systems. It discusses new neuroimaging techniques, new surgical strategies, and more aggressive surgical approaches in cases with catastrophic epilepsies. The contributors also analyze the improved statistics of surgical outcome in different epilepsy types. This definitive textbook is an invaluable reference for neurologists, neurosurgeons, epilepsy specialists, and those interested in epilepsy and its surgical treatment. |
| epilepsy a comprehensive textbook volume 1: Encyclopedia of Basic Epilepsy Research , 2009-05-27 As a truly translational area of biomedical investigation, epilepsy research spans an extraordinary breadth of subjects and involves virtually every tool that modern neuroscience has at its disposal. The Encyclopedia of Basic Epilepsy Research provides an up to date, comprehensive reference for all epilepsy researchers. With an expert list of authors, the encyclopedia covers the full spectrum of research activities from genes and molecules to animal models and human patients. The encyclopedia's electronic format also provides unparalleled access to frequent updates and additions, while the limited edition print version provides another option for owning this content. The Encyclopedia of Basic Epilepsy Research is an essential resource for researchers of all levels and clinicians who study epilepsy. The only comprehensive reference for basic research and current activities in epilepsy Electronic format provides fast and easy access to updates and additions, with limited print version available as well Contains over 85 articles, all written by experts in epilepsy research |
| epilepsy a comprehensive textbook volume 1: Behavioral Aspects of Epilepsy Gregory L. Holmes, MD, Steven C. Shachter, MD, Dorothee GA Kasteleijn-Nolst Trenite, MD MPH, 2007-10-15 The field of epilepsy and behavior has grown considerably in the past number of years, reflecting advances in the laboratory and clinic. Behavioral Aspects of Epilepsy: Principles and Practice is the definitive text on epilepsy behavioral issues, from basic science to clinical applications, for all neurologists, psychosocial specialists, and researchers in the fields of epilepsy, neuroscience, and psychology/psychiatry. Behavioral aspects of epilepsy include a patient's experiences during seizures, his or her reaction during and between seizures, the frequency of episodes and what can be determined from the number of seizures. With contributions by dozens of leading international experts, this is the only book to cover all aspects of this critical emerging science. Adult and pediatric patients, animal models, and epilepsy surgery and its effects are all covered in detail. Behavioral Aspects of Epilepsy is the only source for up-to-date information on a topic that has significant and growing interest in the medical community. This comprehensive, authoritative text has a bench to bedside, approach that covers: The mechanisms underlying epilepsy and behavior Neurophysiologic function Neuropsychiatric and behavioral disorders in patients with epilepsy The effects of treatments and surgery on behavior Pediatric and adolescent epilepsy Disorders associated with epilepsy that impact behavior And much more |
| epilepsy a comprehensive textbook volume 1: Dietary Treatment of Epilepsy Elizabeth Neal, 2012-09-17 Epilepsy is a common chronic neurological disorder characterised by recurrent unprovoked seizures, and affects 50 million people worldwide. Approximately 30% of these do not have seizure control even with the best available medications, hence renewed and increasing interest in the use of dietary treatments to treat epilepsy. These treatments include the traditional ketogenic diets but also the newer modified Atkins diet and low glycaemic index treatment. The ketogenic diet is a high-fat, adequate-protein, low-carbohydrate diet that in medicine is used primarily to treat refractory epilepsy in children, and requires the dedicated support of a multi-disciplinary team including doctors and dietitians. Dietary Treatment of Epilepsy: Practical Implementation of Ketogenic Therapy provides comprehensive and practical training on all aspects of implementing and managing dietary treatments for epilepsy, with key chapters on assessment, calculations, implementation, monitoring and complications. Edited by a highly respected expert in the field supported by a strong team of contributors, this is a must-have resource for paediatric dietitians and other members of the therapy team. |
| epilepsy a comprehensive textbook volume 1: Imaging of Epilepsy John M. Stern, Noriko Salamon, 2022-01-03 This clinically-oriented collection of brain imaging results provides a unique and helpful approach to the epilepsy evaluation. The atlas is divided into sections according to general clinical categories with each category including a collection of clinical examples that span the category. Each example includes images across the relevant imaging modalities that relate to one patient, whose history accompanies the images. This case-based organization with clinical history and multiple images offers a complete visual understanding of the imaging findings and the corresponding relationship of each finding to the clinical presentation, treatment, and outcome. Images for the book are from the UCLA Seizure Disorder Center, which is a referral center that serves a large outpatient epilepsy patient population and performs approximately 500 inpatient epilepsy evaluations annually. Comprehensive and richly illustrated, this book will serve as a convenient resource in neurologic and radiologic practice, and useful for board exam review. |
| epilepsy a comprehensive textbook volume 1: Magnetic Resonance in Epilepsy Ruben Kuzniecky, Graeme D. Jackson, 2005-01-19 Remarkable advances in imaging have increased the importance of MRI for diagnostic, treatment and management of epilepsy. Neuroimaging of patients with epilepsy no longer simply deals with the technology and interpretation of images but also with issues of brain metabolism, energetics, cognition and brain dysfunction. The first edition of Magnetic Resonance in Epilepsy came into clinical practice in 1995 with a revolutionary idea; that is, MR is as important as EEG in the clinical management of patients with epilepsy. The second edition of Magnetic Resonance in Epilepsy, the only comprehensive text in the field of epilepsy neuroimaging, reviews fundamental concepts and new advances in MR technology, computerized analysis, MR spectroscopy, DWI and other neuroimaging techniques such as PET, SPECT and MEG application to the study of patients with epileptic disorders.*Provides a crucial update of recent advances in imaging techniques*Timely publication as subject of neuroimaging is a very hot area in both clinical epilepsy and basic neuroscience research*Editors are well-respected in this field |
| epilepsy a comprehensive textbook volume 1: Temporal Lobe Epilepsy and the Mind-Brain Relationship: A New Perspective Shirley Ferguson, 2006-12-01 This book is devoted to the surgical treatment of epilepsy and its consequences, and provides an extraordinary perspective on the fascinating question of the relationship between brain and mind. Contrary to the current emphasis on statistics and objectivity, this book is dedicated to understanding the whole person, the life and experiences of the individual. It reports on cutting-edge technical skills provided with a human touch. This book reflects the understanding that the temporolimbic seizure originates in tissue providing the substrate for the emotional life and memory. Finally, it emphasizes the value of clinical research – here, conducted in the course of the diagnosis and surgical treatment of epilepsy – in helping to elucidate the relationship between brain and mind. |
| epilepsy a comprehensive textbook volume 1: Epilepsy in Women Cynthia Harden, Sanjeev V. Thomas, Torbjorn Tomson, 2013-01-02 Epilepsy requires careful management and monitoring through a woman’s life Epilepsy is a complex disease. The hormonal changes women experience, both day-to-day menstrual fluctuations and the longer waxes and wanings of a reproductive lifetime, make the management of epilepsy even more complicated. At some point, the well-being of a second person, a fetus, might also have to be taken into account. Epilepsy in Women provides a detailed guide to this challenge. The wide-ranging approach encompasses all aspects of a woman’s life including: Social and psychological impacts The impact in reproductive life Contraception Pregnancy Fetal health and long term developmental outcomes Lactation Menopause Each practical chapter begins and ends with a case study that demonstrates the more general challenge. The authors develop themes to provide clinical guidance based on evidence and experience. Written and edited by an international cast of experts, Epilepsy in Women provides crucial tips and recommendations for neurologists and gynecologists who need to be aware of the subtle effects of epilepsy on woman’s life. |
| epilepsy a comprehensive textbook volume 1: Seizures and Epilepsy in Children Eileen P. G. Vining, Carl Stafstrom, Eric Kossoff, Adam Hartman, Sarah Kelley, Sarah Doerrer, Christa Habela, Cynthia Salorio, Samata Singhi, 2022-12-27 Seizures and Epilepsy in Children is the go-to resource for caregivers and families with children who have epilepsy and seizures. |
| epilepsy a comprehensive textbook volume 1: Epilepsy in Children and Adolescents James W. Wheless, Dave F. Clarke, Amy L. McGregor, Philip L. Pearl, Yu-Tze Ng, 2012-10-22 Epilepsy in childhood presents a profound challenge Epilepsy is an unsettling, complex condition. There is no ‘one size fits all’ option. For effective treatment a full understanding of each patient’s situation and clinical history is needed. Recent remarkable improvements in our ability to image brain structures, to define physiological patterns and in treatment options has made the task of care of the child with epilepsy potentially more effective. Epilepsy in Children and Adolescents provides the contemporary, caring guidance you need to diagnose and manage seizures in a young patient. Beginning with an overview of the classification of epilepsy syndromes, the experienced authors cover: Diagnostic evaluation of childhood epilepsies Principles of treatment Generalized seizures and generalized epilepsy syndromes Partial onset seizures and localization-related epilepsy syndromes Epilepsies relative to age, etiology or duration The full range of treatment options: medical, dietary, surgical Epilepsy in Children and Adolescents takes a practical approach to a common but complex clinical challenge. |
| epilepsy a comprehensive textbook volume 1: Epilepsy Board Review Mohamad Z. Koubeissi, Nabil J. Azar, 2017-06-27 This concise text mirrors the content of the Epilepsy Board as distributed by the American Board of Psychiatry and Neurology. Epilepsy diagnosis, classification and treatment are thoroughly covered, along with seizure classification, epidemiology, normal and abnormal EEG, and treatment with antiepileptic medications and other modalities. Formatted with multiple choice questions and explanations, this complete resource will prepare physicians and students for the Epilepsy Board examination and provide the latest clinical approaches. |
| epilepsy a comprehensive textbook volume 1: Women with Epilepsy Esther Bui, Autumn M. Klein, 2014-07-31 This is a succinct, portable, essential guide to the practical management of women with epilepsy for busy clinicians. |
| epilepsy a comprehensive textbook volume 1: Neurology and Clinical Neuroscience E-Book Anthony H. V. Schapira, 2006-12-18 This brand-new text provides you with an easy-to-use, comprehensive reference that features a clinical perspective balanced with relevant basic science. Inside, you'll find discussions of the latest research and how it has led to a greater understanding of the cause of disease, as well as burgeoning tests and the latest therapeutic agents available. From Alzheimer's disease to vestibular system disorders, you'll find the practical guidance you need to diagnose effectively and provide an appropriate therapeutic approach for each individual case. Plus, a templated, four-color design offers you easy access to pertinent information Integrates basic science with clinical neurology to help you better understand neurologic diseases and provide the most accurate diagnosis and best treatment plan for each patient. Discusses the latest research results and offers new information on treatment options. Features the expertise of international authorities, providing a worldwide perspective. Uses a templated, four-color format that makes information accessible and easy to understand—particularly the basic science concepts. |
| epilepsy a comprehensive textbook volume 1: Aminoff's Electrodiagnosis in Clinical Neurology E-Book Michael J. Aminoff, 2012-04-02 Appropriately select, implement, and interpret electrodiagnostic tests to identify a full range of central and peripheral nervous system disorders with Aminoff's Electrodiagnosis in Clinical Neurology! Covering everything from basic principles to the latest advances in electrodiagnosis, this medical reference book helps you make optimal use of this powerful but complex diagnostic modality in compliance with regulatory and professional standards, so you can diagnose patients accurately and initiate effective treatment and management strategies. - Deepen your understanding of the principles, scope, limitations, diagnostic importance, prognostic relevance, and complications for each technique. - Visually grasp the technical and practical aspects of electrodiagnostic tests with almost 800 charts, figures, and tables. - Rely on the knowledge, experience, and perspective of renowned expert Dr. Michael J. Aminoff and an international team of contributors comprised of a virtual who's who of clinical neurophysiology. - Keep up with developments in the field through significant updates, including new chapters on Artifacts and Normal Variants in the Electroencephalogram; Microneurography; Clinical Applications of Nerve Excitability Testing; Ultrasound of Muscle and Nerve; The Blink Reflex and Other Brainstem Reflexes; Visual Evoked Potentials,Electroretinography and Other Diagnostic Approaches to the Visual System; and Magnetic Stimulation in Clinical Practice and Research. - Access information on the go from your laptop or mobile device via expertconsult.com, featuring fully searchable text, and links to PubMed. - Meet regulatory and professional standards and apply best practices with state-of-the-art guidance (for both non-specialists and specialists) emphasizing the clinical applications of each electrodiagnostic technique. - Get easily actionable information and avoid mistakes with electrophysiologic findings integrated into the clinical context in which they are obtained. |
| epilepsy a comprehensive textbook volume 1: Medication-Resistant Epilepsy John M. Stern, Raman Sankar, Michael Sperling, 2020-09-10 A practical yet comprehensive review of the underlying causes of medication-resistant epilepsy and effective forms of treatment. |
| epilepsy a comprehensive textbook volume 1: Atlas of Epilepsies S.R. Benbadis, R.G. Beran, A.T. Berg, J. Engel, Jr., A.S. Galanopoulou, P.W. Kaplan, M. Koutroumanidis, S.L. Moshe, D.R. Nordli, Jr., J.M. Serratosa, S.M. Sisodiya, W.O. Tatum, T. Valeta, A. Wilner, 2010-09-20 Atlas of Epilepsies is a landmark, all-encompassing, illustrated reference work and hands-on guide to the diagnosis, management and treatment of epilepsy in all its forms and across all age groups. The premier text in the field with over one thousand images, the Atlas’s highly illustrative approach tackles the difficult subject of epileptic seizures and epileptic syndromes, accompanied by sequential photographs of each management step. Intraoperative photographs are accompanied by detailed figure legends describing nuances, subtleties, and the thought processes involved in each step, providing a fuller understanding of each procedure. The Atlas draws on the expertise of over 300 internationally-renowned experts, and is liberally interspersed with clinical insights and personal vignettes that offer helpful tips, technical advice and critical knowledge to the clinician and scholar. The thorough and complete table of contents includes dedicated sections or chapters on important topics such as neonatal and pediatric seizures; imitators of epilepsy; EEG and neuroimaging; psychiatric and quality of life aspects of epilepsy; and a complete guide to treatment options including current and up-to-date chapters on pharmaceuticals, surgical procedures, and additional and alternative treatments. No other publication addresses epilepsies as thoroughly and completely as the Atlas of Epilepsies. Exhaustive and illustrative, convenient and current, this reference is sure to be the premier text on epilepsy for many years to come. |
| epilepsy a comprehensive textbook volume 1: The Causes of Epilepsy Simon D. Shorvon, Frederick Andermann, Renzo Guerrini, 2011-04-14 Causation is an aspect of epilepsy neglected in the scientific literature and in the conceptualization of epilepsy at a clinical and experimental level. It was to remedy this deficiency that this book was conceived. The book opens with a draft etiological classification that goes some way to filling the nosological void. The book is divided into four etiological categories: idiopathic, symptomatic, cryptogenic, and provoked epilepsies. Each chapter considers topics in a consistent fashion, dealing with the phenomenon of epilepsy in each etiology, including its epidemiology, clinical features and prognosis, and any specific aspects of treatment. The book is a comprehensive reference work, a catalogue of all important causes of epilepsy, and a clinical tool for all clinicians dealing with patients who have epilepsy. It is aimed at epileptologists and neurologists and provides a distillation of knowledge in a form that is helpful in the clinical setting. |
| epilepsy a comprehensive textbook volume 1: Epilepsy John W. Miller, Howard P. Goodkin, 2014-01-06 Epilepsy is common but complex Epilepsy is a complicated neurological condition with variable manifestations, numerous etiologies, and a diverse range of treatments. It is a chronic disease that, in many cases, can be controlled. However, treatment requires accurate clinical evaluation to allow intelligent treatment choices. Epilepsy has been designed to help you develop these evaluation skills. Expert neurologists have distilled the evidence and combined their experience. They provide practical guidance to: The causes and classification of epilepsy Working up seizures Antiepileptic medications Pediatric epilepsy Adult epilepsy Emergency epilepsy Comorbidity and mortality of epilepsy Clinical in approach, practical in execution, Epilepsy is packed with tricks, tips, and focused advice to help you better manage your patients’ seizures. |
| epilepsy a comprehensive textbook volume 1: Brainstorm Suzanne O'Sullivan, 2018-04-05 'I loved it. She is in my view the best science writer around - a true descendant of Oliver Sacks' Sathnam Sanghera, author of The Boy with the Topknot The brain is the most complex structure in the universe. In Brainstorm the Wellcome Prize-winning author of It’s All in Your Head uncovers the most eye-opening symptoms medicine has to offer. ‘Powerfully life-affirming... Brainstorm is testament to O'Sullivan's unshowy clarity of thought and her continued marvelling at the mysteries of the brain’ Guardian Brainstorm examines the stories of people whose symptoms are so strange even their doctor struggles to know how to solve them. A man who sees cartoon characters running across the room; a teenager who one day arrives home with inexplicably torn clothes; a girl whose world turns all Alice in Wonderland; another who transforms into a ragdoll whenever she even thinks about moving. The brain is the most complex structure in the universe, and neurologists must puzzle out life-changing diagnoses from the tiniest of clues – it’s the ultimate in medical detective work. In this riveting book, one of the UK’s leading neurologists takes you with her as she follows the trail of her patients’ symptoms: feelings of déjà vu lead us to a damaged hippocampus; spitting and fidgeting to the right temporal lobe; fear of movement to a brain tumour; a missed heart beat to the limbic system. It’s a journey that will open your eyes to the unfathomable intricacies of the brain, and the infinite variety of human capacity and experience. |
| epilepsy a comprehensive textbook volume 1: A Clinical Guide to Epileptic Syndromes and their Treatment C. P. Panayiotopoulos, 2010-05-10 A disorder which affects 4 percent of children and 1-2 percent of the general population, epilepsy is one of the most common neurological disorders. The original edition of C.P. Panayiotopoulos’ guide proved to be the only one of its kind, covering many important aspects of diagnosis and treatment. Due to the continued advances being made in the subject, a second edition is now due. The text includes detailed diagnostics, concise descriptions of syndromes, a wealth of practical tips, and is supported by useful tables to enable clear diagnoses. Building on the sell-out success of the first edition this thorough revision reflects the latest report of the ILAE classification core group and the significant progress made in the diagnosis, classification and treatment of the epilepsies. This new edition is indispensable reading for all those who care for patients with epileptic seizures. |
| epilepsy a comprehensive textbook volume 1: Handbook of Pediatric Epilepsy David C. Dredge, 2016-07-10 Epilepsy is the most common neurological problem affecting children and adolescents, with an incidence rate of 1–2%. Diagnosing epilepsy in children is often complicated by age-dependent manifestations which can differ greatly from seizure disorders seen in adults. Thus, effective treatment and management depends on clinicians to establish an accurate diagnosis and choose appropriate therapy based on the likelihood of clinical benefit. Handbook of Pediatric Epilepsy will be a concise overview of seizures in infants, children, and adolescents, including a discussion of common types of seizure disorders, treatment options, recent drug developments, and evidence-based disease management guidelines. |
| epilepsy a comprehensive textbook volume 1: Wyllie's Treatment of Epilepsy Elaine Wyllie, Gregory D. Cascino, Barry E. Gidal, 2010-11-23 In one convenient source, Wyllie's Treatment of Epilepsy: Principles and Practice provides a broad, detailed, and cohesive overview of seizure disorders and contemporary treatment options. For this Fifth Edition, the editors have replaced or significantly revised approximately 30 to 50 percent of the chapters, and have updated all of them. Dr. Wyllie has invited three new editors: Gregory Cascino, MD, FAAN, at Mayo Clinic, adult epileptologist with special expertise in neuroimaging; Barry Gidal, PharmD, at University of Wisconsin, a pharmacologist with phenomenal expertise in antiepileptic medications; and Howard Goodkin, MD, PhD, a pediatric neurologist at the University of Virginia. A fully searchable companion website will include the full text online and supplementary material such as seizure videos, additional EEG tracings, and more color illustrations. |
| epilepsy a comprehensive textbook volume 1: Canine Epilepsy Caroline D. Levin, 2002 Takes a close look at the most common neurological disorder diagnosed in dogs. This work provides owners with discussions of nervous system function, and why seizures occur. It examines seizure triggers, and the clear links to metabolism and brain activity. It discusses traditional medical treatments, as well as various alternative therapies. |
| epilepsy a comprehensive textbook volume 1: Handbook of Brain Connectivity Viktor K. Jirsa, A.R. McIntosh, 2007-08-16 Our contemporary understanding of brain function is deeply rooted in the ideas of the nonlinear dynamics of distributed networks. Cognition and motor coordination seem to arise from the interactions of local neuronal networks, which themselves are connected in large scales across the entire brain. The spatial architectures between various scales inevitably influence the dynamics of the brain and thereby its function. But how can we integrate brain connectivity amongst these structural and functional domains? Our Handbook provides an account of the current knowledge on the measurement, analysis and theory of the anatomical and functional connectivity of the brain. All contributors are leading experts in various fields concerning structural and functional brain connectivity. In the first part of the Handbook, the chapters focus on an introduction and discussion of the principles underlying connected neural systems. The second part introduces the currently available non-invasive technologies for measuring structural and functional connectivity in the brain. Part three provides an overview of the analysis techniques currently available and highlights new developments. Part four introduces the application and translation of the concepts of brain connectivity to behavior, cognition and the clinical domain. |
| epilepsy a comprehensive textbook volume 1: Intractable Focal Epilepsy John Oxbury, C. E. Polkey, Michael Duchowny, 2000 Intractable Focal Epilepsyis a definitive multi author reference work covering the most difficult to treat epilepsies. The natural history, pathology and treatment, both medical and surgical, of the conditions underlying intractable seizures are fully described and illustrated. Including contributions from North America, Europe and the Pacific Rim, the emphasis throughout is on clinical diagnosis and treatment both medical and surgical, and their respective outcomes. The text is enhanced by over 250 illustrations, and the clear modern design enables the reader to assimilate information quickly. In addition to clinical treatment, there is a section on the costs of persistent intractable focal epilepsy and the costs of surgical treatment. Drs Oxbury, Polkey and Duchowny have produced a book that will appeal to epileptologists, paediatric neurologists, and neurosurgeons. The books clinical strengths will make it an invaluable working tool. Definitive resource on difficult to treat epilepsies Covers manifestation, consequences and treatment Major section on surgical treatment of focal epilepsy Complete coverage of paediatric diagnosis and treatment Special Case Reports give practical case histories to illustrate clinical points International line up of contributors |
Epilepsy - Symptoms and causes - Mayo Clinic
Oct 14, 2023 · Epilepsy — also known as a seizure disorder — is a brain condition that causes recurring seizures. There are many types of …
Epilepsy - Diagnosis and treatment - Mayo Clinic
Oct 14, 2023 · The exam helps diagnose epilepsy and determine the type of epilepsy you may have. Blood tests. A blood sample can detect signs of …
Epilepsia - Síntomas y causas - Mayo Clinic
Dec 30, 2023 · Síntomas. Los síntomas de las convulsiones varían según el tipo de convulsión. Dado que la epilepsia se debe a cierta actividad en el cerebro, …
Epilepsy - Overview - Mayo Clinic
Mar 22, 2025 · As a Level 4 comprehensive epilepsy center, Mayo Clinic is positioned to identify the best treatment for people whose epilepsy …
Seizures - Symptoms and causes - Mayo Clinic
Nov 1, 2024 · A seizure is a sudden burst of electrical activity in the brain. It can cause changes in behavior, movements, feelings and levels of …
Epilepsy - Symptoms and causes - Mayo Clinic
Oct 14, 2023 · Epilepsy — also known as a seizure disorder — is a brain condition that causes recurring seizures. There are many types of epilepsy. In some people, the cause can be …
Epilepsy - Diagnosis and treatment - Mayo Clinic
Oct 14, 2023 · The exam helps diagnose epilepsy and determine the type of epilepsy you may have. Blood tests. A blood sample can detect signs of infections, genetic conditions or other …
Epilepsia - Síntomas y causas - Mayo Clinic
Dec 30, 2023 · Síntomas. Los síntomas de las convulsiones varían según el tipo de convulsión. Dado que la epilepsia se debe a cierta actividad en el cerebro, las convulsiones pueden …
Epilepsy - Overview - Mayo Clinic
Mar 22, 2025 · As a Level 4 comprehensive epilepsy center, Mayo Clinic is positioned to identify the best treatment for people whose epilepsy doesn't respond to medicines. These treatment …
Seizures - Symptoms and causes - Mayo Clinic
Nov 1, 2024 · A seizure is a sudden burst of electrical activity in the brain. It can cause changes in behavior, movements, feelings and levels of consciousness. Epilepsy is defined as having two …
Epilepsy: Symptoms, Causes, Complications and What You Can Do
Nov 19, 2013 · Mayo Clinic Health System neurologist Andrew Reeves, M.D., helps explain epilepsy and seizures. Symptoms and types of seizures. Categorized as a spectrum disorder …
Explaining epilepsy - Mayo Clinic
Apr 28, 2023 · Around 3 million people in the U.S. have epilepsy, making it the fourth most common neurological disease after migraine, stroke and Alzheimer's. Epilepsy happens as a …
Epilepsy - Care at Mayo Clinic
Oct 14, 2023 · Mayo Clinic epilepsy care teams have experience treating epilepsy to eliminate seizures or reduce the frequency and intensity of seizures in children and adults. Treatment …
Autoimmune epilepsy - Diagnosis and treatment - Mayo Clinic
Dec 21, 2024 · An autoimmune epilepsy diagnosis begins with a physical exam and a review of your symptoms. Testings for autoimmune epilepsy includes lab tests, brain imaging and …
Epilepsy - Doctors and departments - Mayo Clinic
Oct 14, 2023 · Mayo Clinic researchers have developed and studied many diagnostic and treatment tools for epilepsy. They include magnetic resonance imaging, subtraction ictal …
