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| downstream processing course: Principles of Downstream Techniques in Biological and Chemical Processes Mukesh Doble, 2016-01-05 Downstream processing is an essential practice in the production and purification of biosynthethic materials, which is especially important in the production of pharmaceutical products. This book covers the fundamentals and the design concepts of various downstream recovery and purification steps (unit operations) involved in biochemical and chemic |
| downstream processing course: Fermentation Processes Brycen Soto, 2019-03-20 Fermentation is a metabolic process that consumes sugar in the absence of oxygen. The products are organic acids, gases, or alcohol. It occurs in yeast and bacteria, and also in oxygen-starved muscle cells, as in the case of lactic acid fermentation. The science of fermentation is known as zymology. Fermentation process by which the living cell is able to obtain energy through the breakdown of glucose and other simple sugar molecules without requiring oxygen. Fermentation is achieved by somewhat different chemical sequences in different species of organisms. Two closely related paths of fermentation predominate for glucose. When muscle tissue receives sufficient oxygen supply, it fully metabolizes its fuel glucose to water and carbon dioxide. Fermentation is a process which does not necessarily have to be carried out in an anaerobic environment. For example, even in the presence of abundant oxygen, yeast cells greatly prefer fermentation to aerobic respiration, as long as sugars are readily available for consumption (a phenomenon known as the Crabtree effect). The antibiotic activity of hops also inhibits aerobic metabolism in yeast. The aim of the book is to provide an in-depth study of the principles of fermentation technology and recent advances and developments in the field of fermentation technology, focusing on industrial applications. |
| downstream processing course: Bioseparations Paul A. Belter, E. L. Cussler, Wei-Shou Hu, 1988-02-22 Offers a concise introduction to the separation and purification of biochemicals. Bridges two scientific cultures, providing an introduction to bioseparations for scientists with no background in engineering and for engineers with little grounding in biology. The authors supplement the ideas by simple worked examples, making the techniques of bioseparations easy to learn. Discusses removal of insolubles, product isolation, purification and polishing. |
| downstream processing course: Genba Kanri Edward Handyside, 1997 An explanation of the disciplines of Genba Kanri. The book looks at management practices required for GK disciplines to function and aims to show how, by connecting people concerns with the operational aspects of manufacturing, GK can improve management and productivity. |
| downstream processing course: Biochemical Engineering and Biotechnology Ghasem Najafpour, 2015-02-23 Biochemical Engineering and Biotechnology, Second Edition outlines the principles of biochemical processes and explains their use in the manufacturing of everyday products. The text covers the major concepts of biochemical engineering and biotechnology, and is an ideal reference for chemical engineering students who need to learn and apply biological knowledge in engineering principles. The author takes a direct, useful approach in presenting the concepts and practical applications, including many solved problems, case studies, examples, and demonstrations of detailed experiments, with simple design equations and required calculations also included. It is ideal for both those interested in more advanced research in the field of biotechnology, also acting as a guide for beginners seeking direction on establishing research in this field. Covers major concepts of biochemical engineering and biotechnology, including applications in bioprocesses, fermentation technologies, enzymatic processes, and membrane separations, amongst others Accessible to chemical engineering students who need to both learn, and apply, biological knowledge in engineering principals Includes solved problems, examples, and demonstrations of detailed experiments with simple design equations and all required calculations Offers many graphs that present actual experimental data, figures, and tables, along with explanations |
| downstream processing course: Downstream Processing of Proteins Mohamed A. Desai, 2008-02-05 Considerable effort and time is allocated to introducing cell culture and fermentation technology to undergraduate students in academia, generally through a range of courses in industrial biotechnology and related disciplines. Similarly, a large number of textbooks are available to describe the appli- tions of these technologies in industry. However, there has been a general lack of appreciation of the significant developments in downstream processing and isolation technology, the need for which is largely driven by the stringent re- latory requirements for purity and quality of injectable biopharmaceuticals. This is particularly reflected by the general absence of coverage of this s- ject in many biotechnology and related courses in educational institutions. For a considerable while I have felt that there is increasing need for an introductory text to various aspects of downstream processing, particularly with respect to the needs of the biopharmaceutical and biotechnology ind- try. Although there are numerous texts that cover various aspects of protein purification techniques in isolation, there is a need for a work that covers the broad range of isolation technology in an industrial setting. It is anticipated that Downstream Processing of Proteins: Methods and Protocols will play a small part in filling this gap and thus prove a useful contribution to the field. It is also designed to encourage educational strategists to broaden the coverage of these topics in industrial biotechnology courses by including accounts of this important and rapidly developing element of the industrial process. |
| downstream processing course: Downstream Process Technology: A New Horizon In Biotechnology Krishna Kant Prasad, Nooralabettu Krishna Prasad, 2010-01-30 Today, biochemical process industry demands fast and economic processes for the partitioning and purification of biomolecules that give high yield and high purity of the product. An integral and cost intensive part of these processes is associated with downstream processing for product isolation and purification. The aim of this comprehensive text is to provide an insightful overview of the whole aspects of downstream processing for biochemical product recovery. Intended for undergraduate and postgraduate students of biotechnology and chemical engineering, this self-contained text includes the chapters based on the recent developments in the industry and academics. It covers the importance of the downstream processing in terms of its relevancy to modern days ever-changing consumer needs, process design criteria relevance to set objectives, and physicochemical factors that help to formulate the strategy to develop a configuration among the raw material, methodology and instruments. This overview is followed by different downstream processing steps. The text concludes with the discussion on stabilization of the product to improve the shelf life of the product. Key Features Includes detailed biological, mathematical, chemical and physical aspects of downstream processing. Distinguishes downstream processing from analytical bioseparation. Contains numerous illustrations and solved problems. |
| downstream processing course: Pharmaceuticals from Microbes Divya Arora, Chetan Sharma, Sundeep Jaglan, Eric Lichtfouse, 2019-01-09 This book has been assembled with the hope of being an authoritative, comprehensive, conceptually sound and highly informative compilation of recent advances describing the concepts of bioengineering in the field of microbiology. It comprises of seven chapters written by eminent authors in their respective fields. Topics included deal with the significant advancement of microbial technology with emphasis on drug delivery strategies for healthcare products, vaccine delivery, biotransformation approaches to generate new molecules, upstream/downstream processing of biopharmaceuticals. It serves as excellent reference material for researchers, students and academicians in the fields of biotechnology, microbiology and pharmaceutical sciences. |
| downstream processing course: Membrane Processes in Separation and Purification J.G. Crespo, Karl W. Böddeker, 2013-11-11 The chapters of this book are based upon lectures presented at the NATO Advanced Study Institute on Membrane Processes in Separation and Purification (March 21 - April 2, 1993, Curia, Portugal), organized as a successor and update to a similar Institute that took place 10 years ago (p.M.Bungay, H.K. Lonsdale, M.N. de Pinho (Eds.): Synthetic Membranes: Science, Engineering and Applications, NATO ASI Series, Reidel, Dordrecht, 1986). The decade between the two NATO Institutes witnesses the transition from individually researched membrane processes to an applied and established membrane separation technology, as is reflected by the contents of the corresponding proceeding volumes. By and large, the first volume presents itself as a textbook on membrane processes, still valid, while the present volume focuses on areas of separation need as amenable to membrane processing: Biotechnology and Environmental Technology. Accordingly, the contributions to this volume are grouped into Membranes in Biotechnology (11 papers), Membranes in Environmental Technology (6 papers), and New Concepts (4 papers). This is followed by one contribution each on Energy Requirements and Education, i.e., membrane processes within an academic curriculum. The book thus amounts to a state of the art of applied membrane processing and may well augment the more fundamental approach of its predecessor. |
| downstream processing course: Protein Chromatography Giorgio Carta, Alois Jungbauer, 2010-06-08 With its focus on process development and large-scale bioseparation tasks, this is tailor-made reading for the professional bioengineer in both the biotech and pharmaceutical industries. Following a tried-and-tested concept, this guide has been developed over several years in training courses for biotech and chemical engineers in Europe and the U.S. The first part deals with the theory, introducing chromatography and its dynamics, as well as discussing mass transfer and dispersion effects. The second part then goes on to cover equipment and protocols, determining the retention factor and HETP from isocratic and elution experiments, as well as the mass transfer and intraparticle diffusivity from batch and shallow-bed adsorption experiments. |
| downstream processing course: Continuous Biomanufacturing Ganapathy Subramanian, 2017-12-26 This is the most comprehensive treatise of this topic available, providing invaluable information on the technological and economic benefits to be gained from implementing continuous processes in the biopharmaceutical industry. Top experts from industry and academia cover the latest technical developments in the field, describing the use of single-use technologies alongside perfusion production platforms and downstream operations. Special emphasis is given to process control and monitoring, including such topics as 'quality by design' and automation. The book is supplemented by case studies that highlight the enormous potential of continuous manufacturing for biopharmaceutical production facilities. |
| downstream processing course: Extractive Industries Tony Addison, Alan Roe, 2018 This book is about the challenges and opportunities facing developing countries in using their extractive industries to achieve inclusive and sustainable development. It recognizes the importance of using oil, gas, and mining to achieve inclusive change. |
| downstream processing course: Introduction to Biomanufacturing Northeast Biomanufacturing Center & Collaborative, 2012-11-03 Today is a time of unparalleled excitement in the world of biopharmaceuticals. This book is a compendium of a tremendous body of knowledge, distilled into its most essential parts. Not only are there theoretical and conceptual ideas about biopharmaceutical manufacturing, but also content specific to skills and abilities. It serves as a well-paced guide for beginning learners as well as a cogent reference for seasoned biotechnology professionals alike. This book will help a new generation of students to become inspired and familiarize themselves with the theories, principles, and vernacular of biopharmaceutical production and all that it entails. A quick overview of contents include; Operational Excellence, Facilities, Metrology, Validation, Environmental Health & Safety (EHS), Quality Assurance, Microbiological Control, Quality Control Biochemistry, Upstream Processing, Downstream Processing, Process Development, and a Master Glossary. |
| downstream processing course: Bioprocess Engineering Pau Loke Show, Chien Wei Ooi, Tau Chuan Ling, 2019-05-24 Bioprocess Engineering: Downstream Processing is the first book to present the principles of bioprocess engineering, focusing on downstream bioprocessing. It aims to provide the latest bioprocess technology and explain process analysis from an engineering point of view, using worked examples related to biological systems. This book introduces the commonly used technologies for downstream processing of biobased products. The covered topics include centrifugation, filtration, membrane separation, reverse osmosis, chromatography, biosorption, liquid-liquid separation, and drying. The basic principles and mechanism of separation are covered in each of the topics, wherein the engineering concept and design are emphasized. This book is aimed at bioprocess engineers and professionals who wish to perform downstream processing for their feedstock, as well as students. |
| downstream processing course: Fermentation Processes and Downstream Processing , 1990 |
| downstream processing course: Animal Cell Technology Manuel J.T. Carrondo, Bryan Griffiths, José L.P. Moreira, 2012-12-06 Animal cell technology has undergone a rapid transformation over the last decade from a research tool and highly specialised technology to a central resource for innovation in pharmaceutical research and development. These proceedings of the 14th Meeting of the European Society for Animal Cell Technology (Vilamoura, Portugal, May 1996) bring up to date the historical perspective of animal cell technology for the benefit of society, `From Vaccines to Genetic Medicine', and will charter this vital technology for the years to come. Strong contributions are grouped in the traditional ESACT areas of 'Cell and Physiology Engineering' dealing with cell state, including genetics, and its environment, and 'Animal Cell Process Engineering' covering integration of bioreaction with bioseparation coupled with on-line monitoring to improve protein production and consistency. Extensive coverage of metabolic engineering on synthesis, folding, assembly, transiting and secretion is dealt with in the session on 'Recombinant Proteins: Biosynthesis and Bioprocessing'. Two traditional but expanding areas of animal cell technology relevance are highlighted in the broad sessions of 'Animal Cells as Tools for Discovery and Testing' and 'Animal Cell Vaccines: Present and Future'. Two sessions finally cover the more recent domains of animal cell technology work - 'Tissue Engineering and Biomedical Devices' and 'Cells and Vectors for Genetic Medicine' - where one can foresee a very bright future. |
| downstream processing course: Mineral Biotechnology 2002 , |
| downstream processing course: Engineering Processes for Bioseparations LAURENCE R. WEATHERLEY, 2013-10-22 The use of biotechnology in chemical synthesis offers up numerous advantages to the engineer in the process industries, but it also presents a number of fundamental challenges and difficulties which impinge directly on separation process requirements. The use of biochemical separations has grown significantly during the past decade, and is especially used in process industries such as healthcare and food processing. However it is becoming increasingly more important in areas such as recycling and waste-water treatment and as industry shifts towards cleaner processes biochemical separations will continue to grow. The two main objectives of this book are to focus on the application of existing separation process techniques to the recovery and purification of biologically derived products and to examine the state of knowledge of new techniques which have future potential. Within these objectives the complexities and breadth of problems associated with biological separations are discussed, specific engineering techniques are featured and their adaptation to biochemical separations are highlighted. |
| downstream processing course: Science SQC, New Quality Control Principle Kakuro Amasaka, 2012-12-06 As is represented by the world's top-level Japanese automotive manufacturers, Japanese manufacturers have been climbing to winning positions in global businesses. The driving force of their success includes responsiveness to diversifying market needs and elevating quality requirements, clarification of development concepts that facilitate new technology, application of technology to product planning and design, advanced production control systems that elaborately utilize state-of-the-art manufacturing technologies, and flexible, efficient production. Many Japanese manufacturers succeeded in fulfilling these factors mainly because they utilize Japanese-style Lean Production Systems or the so-called Toyota Production System (TPS) and Japanese-style, scientific quality management approaches such as Statistical Quality Control (SQC) and Total Quality Management (TQM) in order to improve their corporate management technology. As severe competition among manufacturers intensify both in Japan and overseas, action against quality problems that remarkably diminish customer satisfaction, and customer-first quality management, is becoming important. Scientific quality control methods that aim to optimize production processes for building in quality were undermined by the past expansion of quantity-oriented manufacturing through automation with massive and heavy equipment. |
| downstream processing course: BIOSPERATIONS B. SIVASANKAR, 2005-01-01 This systematically organized and well-balanced book compresses within the covers of a single volume the theoretical principles and techniques involved in bio-separations, also called downstream processing. These techniques are derived from a range of subjects, for example, physical chemistry, analytical chemistry, bio-chemistry, biological science and chemical engineering. Organized in its 15 chapters, the text covers in the first few chapters topics related to chemical engineering unit operations such as filtration, centrifugation, adsorption, extraction and membrane separation as applied to bioseparations. The use of chromatography as practiced at laboratory as well as industrial scale operation and related techniques such as gel filtration, affinity and pseudoaffinity chromatography, ion-exchange chromatography, electrophoresis and related methods have been discussed. The important applications of these techniques have also been highlighted. |
| downstream processing course: Dynamic Capacity Management for Healthcare Pierce Story, 2010-12-08 While hospitals can learn from other industries, they cannot be improved or run like factories. With work that is more individualized than standardized, and limited control over volume and arrivals, even the leanest-minded hospital must recognize that healthcare systems are more dynamic than nearly any work environment.Written with the creativity n |
| downstream processing course: Industrial Biotechnology Debabrata Das, Soumya Pandit, 2021-05-06 Industrial Biotechnology offers a comprehensive overview of biochemical processes, technologies, and practical applications of industrial biotechnology. The work comprises of chapters that discuss medium preparation, inoculum preparation using industrial strain and upstream processing, various fermentation processes, and physico-chemical separation processes for the purification of products and packaging. Analyzes problems within biochemical processes Discusses stoichiometry of bioprocesses Covers upstream and downstream processing Offers a wealth of case studies of different biochemical production processes, including those in development of food products, vaccines and medicines, single cell proteins, amino acids, cheese, biodiesel, biopesticides, and more This book is aimed at advanced students, industrial practitioners, and researchers in biotechnology, food engineering, chemical engineering, and environmental engineering. |
| downstream processing course: Agricultural Biotechnology G. J. Persley, Reginald MacIntyre, 2002 This book, through its overview chapter and 12 country studies, provides useful information on the evolving biotechnological research in Asia, Africa, and Latin America. The emphasis is on the potential biotechnologies hold for agriculture in developing countries. The reports vary in depth of coverage, but all combine to show the urgent need that exists for public- and private-sector investment to ensure that all countries share in the benefits of modern biotechnologies, while minimizing any unintended effects. The book contains a subject index. |
| downstream processing course: Plasmid Biopharmaceuticals Duarte Miguel F. Prazeres, 2011-08-04 The book addresses the basics, applications, and manufacturing of plasmid biopharmaceuticals. The survey of the most relevant characteristics of plasmids provides the basics for designing plasmid products (applications) and processes (manufacturing). Key features that the authors include in the book are: i) consistency and clear line of direction, ii) an extensive use of cross-referencing between the individual chapters, iii) a rational integration of chapters, iv) appellative figures, tables and schemes, and v) an updated, but selected choice of references, with a focus on key papers. |
| downstream processing course: Protein Chromatography Giorgio Carta, Alois Jungbauer, 2020-06-02 An all-in-one practical guide on how to efficiently use chromatographic separation methods Based on a training course that teaches the theoretical as well as practical aspects of protein bioseparation to bioprocess professionals, this fully updated and revised new edition offers comprehensive coverage of continuous chromatography and provides readers with many relevant examples from the biopharmaceutical industry. Divided into two large parts, Protein Chromatography: Process Development and Scale-Up, Second Edition presents all the necessary knowledge for effective process development in chromatographic bioseparation, both on small and large scale. The first part introduces chromatographic theory, including process design principles, to enable the reader to rationalize the set-up of a bioseparation process. The second part illustrates by way of case studies and sample protocols how the theory learned in the first part may be applied to real-life problems. Chapters look at: Downstream Processing of Biotechnology Products; Chromatography Media; Laboratory and Process Columns and Equipment; Adsorption Equilibrium; Rate Processes; and Dynamics of Chromatography Columns. The book closes with chapters on: Effects of Dispersion and Rate Processes on Column Performance; Gradient Elution Chromatography; and Chromatographic Column Design and Optimization. -Presents the most pertinent examples from the biopharmaceutical industry, including monoclonal antibodies -Provides an overview of the field along with design tools and examples illustrating the advantages of continuous processing in biopharmaceutical productions -Focuses on process development and large-scale bioseparation tasks, making it an ideal guide for the professional bioengineer in the biotech and pharma industries -Offers field-tested information based on decades of training courses for biotech and chemical engineers in Europe and the U.S. Protein Chromatography: Process Development and Scale-Up, Second Edition will appeal to biotechnologists, analytical chemists, chromatographers, chemical engineers, pharmaceutical industry, biotechnological industry, and biochemists. |
| downstream processing course: Protein Liquid Chromatography M. Kastner, 2000 Protein Liquid Chromatography is a handbook-style guide to liquid chromatography as a tool for isolating and purifying proteins, consisting of 25 individual chapters divided into three parts: Part A covers commonly-used, classic modes of chromatography such as ion-exchange, size-exclusion, and reversed-phase; Part B deals with various target protein classes such as membrane proteins, recombinant proteins, and glycoproteins; and Part C looks at various miscellaneous related topics, including coupling reaction, buffer solution additives, and software. The text as a whole can be viewed as a systematic survey of available methods and how best to use them, but also attempts to provide an exhaustive coverage of each facet. How to solve a specific problem using a chosen method is the overall essence of the volume. The principle philosophy of this compilation is that practical application is everything; therefore, both classical and modern methods are presented in detail, with examples involving conventional, medium- and high-pressure techniques. Over-exposure to history, concept, and theory has deliberately been avoided. The reader will find a wealth of tips and tricks from users for users, including advice on the advantages and disadvantages of each method. Easy-to-read sections on Getting started now and Where to go from here attempt to provide hands-on, fool-proof detailed practical procedures with complete and even standard model runs for any scientist or technician at work in this area. |
| downstream processing course: Safety in Industrial Microbiology and Biotechnology C. H. Collins, A. J. Beale, 2015-09-03 Safety in Industrial Microbiology and Biotechnology reviews the hazards involved in work with both naturally occurring and genetically-modified microorganisms. This text is divided into 12 chapters and begins with an overview of the laboratory- and industry-associated infection hazards. The subsequent chapters deal with the legal issues, containment, risk assessment, and pathogenicity testing of infection related to industrial microbiology and biotechnology. These topics are followed by discussions of the safety considerations in recombinant plasmid preparation, the safe handling of industrially-produced mammalian cells, and some genetic designs that can be applied to processes based on recombinant DNA microorganisms. Other chapters explore the design for safety in bioprocessing and the containment in the development and manufacture of recombinant DNA-derived products. The remaining chapters look into the monitoring and validation in biotechnological processes, as well as the occupational health implications of industrial biotechnology. This book will prove useful to biotechnologists, microbiologists, safety engineers, and researchers. |
| downstream processing course: Managing Service Delivery Processes Jean Harvey, 2005-06-07 The quest for value drives customer behavior in the services marketplace. This book focuses on complex service processes, and is written for professionals, quasi-professionals, and technical workers laboring in all spheres, from law to medicine, and accounting to engineering. It draws its theory and examples from these professional services and many more, with hands-on end-of-chapter exercises on all topics. A framework is presented for understanding how a set of shared fundamental beliefs drives the best-in-class professional service organizations in their learning, which is the source of sustained competitive advantage. Products and processes can be imitated or copied, but learning faster than your competition cannot. Processes create the benefits customers want by delivering the service, or by making this delivery possible in one way or another. The notions, methods, and tools presented in this book present readers with a perspective on their work they most likely never envisaged, and which will lead to a marked improvement in their effectiveness. |
| downstream processing course: Bioprocess Technology Mr. Rohit Manglik, 2024-01-12 EduGorilla Publication is a trusted name in the education sector, committed to empowering learners with high-quality study materials and resources. Specializing in competitive exams and academic support, EduGorilla provides comprehensive and well-structured content tailored to meet the needs of students across various streams and levels. |
| downstream processing course: SEE Directory of Awards National Science Foundation (U.S.). Directorate for Science and Engineering Education, 1989 |
| downstream processing course: BIOTECHNOLOGY - Volume XV Horst W. Doelle, J. Stefan Rokem, Marin Berovic , 2009-11-16 This Encyclopedia of Biotechnology is a component of the global Encyclopedia of Life Support Systems (EOLSS), which is an integrated compendium of twenty one Encyclopedias. Biotechnology draws on the pure biological sciences (genetics, animal cell culture, molecular biology, microbiology, biochemistry, embryology, cell biology) and in many instances is also dependent on knowledge and methods from outside the sphere of biology (chemical engineering, bioprocess engineering, information technology, biorobotics). This 15-volume set contains several chapters, each of size 5000-30000 words, with perspectives, applications and extensive illustrations. It carries state-of-the-art knowledge in the field and is aimed, by virtue of the several applications, at the following five major target audiences: University and College Students, Educators, Professional Practitioners, Research Personnel and Policy Analysts, Managers, and Decision Makers and NGOs. |
| downstream processing course: Plywood and Veneer-based Products Richard F. Baldwin, 2016 |
| downstream processing course: Introduction to Chemical Engineering Uche P. Nnaji, 2019-09-30 The field of chemical engineering is undergoing a global “renaissance,” with new processes, equipment, and sources changing literally every day. It is a dynamic, important area of study and the basis for some of the most lucrative and integral fields of science. Introduction to Chemical Engineering offers a comprehensive overview of the concept, principles and applications of chemical engineering. It explains the distinct chemical engineering knowledge which gave rise to a general-purpose technology and broadest engineering field. The book serves as a conduit between college education and the real-world chemical engineering practice. It answers many questions students and young engineers often ask which include: How is what I studied in the classroom being applied in the industrial setting? What steps do I need to take to become a professional chemical engineer? What are the career diversities in chemical engineering and the engineering knowledge required? How is chemical engineering design done in real-world? What are the chemical engineering computer tools and their applications? What are the prospects, present and future challenges of chemical engineering? And so on. It also provides the information new chemical engineering hires would need to excel and cross the critical novice engineer stage of their career. It is expected that this book will enhance students understanding and performance in the field and the development of the profession worldwide. Whether a new-hire engineer or a veteran in the field, this is a must—have volume for any chemical engineer’s library. |
| downstream processing course: Burger's Medicinal Chemistry, Drug Discovery and Development, 8 Volume Set , 2021-04-20 Burger’s Medicinal Chemistry, Drug Discovery and Development Explore the freshly updated flagship reference for medicinal chemists and pharmaceutical professionals The newly revised eighth edition of the eight-volume Burger’s Medicinal Chemistry, Drug Discovery and Development is the latest installment in this celebrated series covering the entirety of the drug development and discovery process. With the addition of expert editors in each subject area, this eight-volume set adds 35 chapters to the extensive existing chapters. New additions include analyses of opioid addiction treatments, antibody and gene therapy for cancer, blood-brain barrier, HIV treatments, and industrial-academic collaboration structures. Along with the incorporation of practical material on drug hunting, the set features sections on drug discovery, drug development, cardiovascular diseases, metabolic diseases, immunology, cancer, anti-Infectives, and CNS disorders. The text continues the legacy of previous volumes in the series by providing recognized, renowned, authoritative, and comprehensive information in the area of drug discovery and development while adding cutting-edge new material on issues like the use of artificial intelligence in medicinal chemistry. Included: Volume 1: Methods in Drug Discovery, edited by Kent D. Stewart Volume 2: Discovering Lead Molecules, edited by Kent D. Stewart Volume 3: Drug Development, edited by Ramnarayan S. Randad and Michael Myers Volume 4: Cardiovascular, Endocrine, and Metabolic Diseases, edited by Scott D. Edmondson Volume 5: Pulmonary, Bone, Immunology, Vitamins, and Autocoid Therapeutic Agents, edited by Bryan H. Norman Volume 6: Cancer, edited by Barry Gold and Donna M. Huryn Volume 7: Anti-Infectives, edited by Roland E. Dolle Volume 8: CNS Disorders, edited by Richard A. Glennon Perfect for research departments in the pharmaceutical and biotechnology industries, Burger’s Medicinal Chemistry, Drug Discovery and Development can be used by graduate students seeking a one-stop reference for drug development and discovery and deserves its place in the libraries of biomedical research institutes, medical, pharmaceutical, and veterinary schools. |
| downstream processing course: Natural Gas Engineering and Safety Challenges Ghasem Nasr, 2014 |
| downstream processing course: Biosensors, Instrumentation & Processing , 1987 |
| downstream processing course: Fibrous Proteins: Structures and Mechanisms David A.D. Parry, John M. Squire, 2017-01-18 This book provides the readers with an up-to-date review of the design, structure and function of a representative selection of fibrous proteins in both health and disease. The importance of the α-helical coiled coil, a conformational motif based on the heptad repeat in the amino acid sequence of all α-fibrous proteins (and parts of some globular proteins) is underlined by three Chapters devoted to its design, structure, function and topology. Specific proteins covered in the text and which depend on the coiled coil for their structure and function, include the intermediate filament proteins, tropomyosin, myosin, paramyosin, fibrin and members of the spectrin superfamily. Also described are fibrous proteins based on the β-pleated sheet and collagen conformations. Recombinant structural proteins, especially of silk and collagen, are discussed in the context of developing new biomaterials with varied applications. Established researchers and postgraduate students in the fields of protein chemistry, biochemistry and structural biophysics will find Fibrous Proteins: Structures and Mechanisms to be an invaluable collection of topical reviews that describe the basic advances made in the field of fibrous proteins over the past decade. This book, written by recognized authorities in the field, provides a clear account of the current status of fibrous protein research and, in addition, establishes the basis for deciding the most appropriate directions for future activity, including the applications of protein engineering and the commercial exploitation of new biomaterials. |
| downstream processing course: Directory of Awards National Science Foundation (U.S.). Directorate for Science and Engineering Education, 1989 |
| downstream processing course: Who's Who in Fluorescence 2009 Chris D. Geddes, 2009-04-02 th The Who’s Who in Fluorescence 2009 is the 7 volume of the Who’s who series. The previous six volumes (2003 – 2008) have been very well received by the fluorescence community, with 1000’s of copies being distributed around the world, through conferences and workshops, as well as through internet book sites. In addition, the Institute of Fluorescence (http://theinstituteoffluorescence.com/) mailed 100’s of copies of the 2008 volume to contributors around the world. This new 2009 volume features some 419 entries from no fewer than 41 countries worldwide, as compared to 418 entries (38 different countries) in 2008 and 405 entries in the 2007 volume, respectively. We have received 29 new entries this year, and deleted 25 entries that were not updated by contributors from past years. In 2008, 129 AIM numbers were submitted as compared to 106 in 2007. This year the number has risen again to 136 AIM numbers submitted. This year we also see the introduction of the h-index number listing, a publication statistic provided by the Thompson’s ISI Web of Science. Some 42 contributors provided their h-numbers. In 2009 we also see a continued and strong company support, in light of the current world economic climate, which will enable us to further disseminate the volume in 2009– 2010. In this regard we especially thank the instrumentation companies for their continued support, where without their financial contributions, it is likely that the volume would not be the success it is today. |
| downstream processing course: Chemical Engineering Problems in Biotechnology Michael A. Winkler, 1990-04-30 |
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