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| catalent 483: Pharmaceuticals, Corporate Crime and Public Health Graham Dukes, John Braithwaite, J P Moloney, 2014-06-27 The pharmaceutical industry exists to serve the community, but over the years it has engaged massively in corporate crime, with the public footing the bill. This readable study by experts in medicine, law, criminology and public health documents the pr |
| catalent 483: Handbook of Pharmaceutical Granulation Technology Dilip M. Parikh, 2016-04-19 The Third Edition presents all pharmaceutical industry personnel and those in academia with critical updates on the recent advances in granulation technology and changes in FDA regulatory guidelines. Addressing precisely how these recent innovations and revisions affect unit operation of particle generation and granulation, this text assists the re |
| catalent 483: The Role of Organismal Oxidative Stress in the Ecology and Life-History Evolution of Animals David Costantini, 2024-09-09 This book illustrates the role of cellular oxidative stress as one of the most important physiological cornerstones in the evolution of biodiversity. The first part of the book provides the fundamentals to navigate the field and analyse the cross-talk between oxidative status homeostasis and other fundamental organismal functions, such as immunity and stress physiology. The second part of the book argues that oxidative stress underpins the astonishing diversity of adaptations to the environments and the evolution of life-history strategies, from growth to reproduction. Unravelling the (un)expected ways through which the need of regulating the organismal oxidative status has influenced the evolution of life, this book presents a novel integrative way of thinking about how a cellular mechanism has shaped the evolution of life and death. |
| catalent 483: Directory of Corporate Counsel, 2025 Edition In house, |
| catalent 483: Federal Register , 2013-08 |
| catalent 483: Directory of Corporate Counsel, Spring 2024 Edition , |
| catalent 483: Protein Oxidation and Aging Tilman Grune, Betul Catalgol, Tobias Jung, Vladimir Uversky, 2012-11-07 Reviews our current understanding of the role of protein oxidation in aging and age-related diseases Protein oxidation is at the core of the aging process. Setting forth a variety of new methods and approaches, this book helps researchers conveniently by exploring the aging process and developing more effective therapies to prevent or treat age-related diseases. There have been many studies dedicated to the relationship between protein oxidation and age-related pathology; now it is possible for researchers and readers to learn new techniques as utilizing protein oxidation products as biomarkers for aging. Protein Oxidation and Aging begins with a description of the tremendous variety of protein oxidation products. Furthermore, it covers: Major aspects of the protein oxidation process Cellular mechanisms for managing oxidized proteins Role of protein oxidation in aging Influence of genetic and environmental factors on protein oxidation Measuring protein oxidation in the aging process Protein oxidation in age-related diseases References at the end of each chapter serve as a gateway to the growing body of original research studies and reviews in the field. |
| catalent 483: Johannesburg , 1998 |
| catalent 483: Current Trends in Monoclonal Antibody Development and Manufacturing Steven J. Shire, Wayne Gombotz, Karoline Bechtold-Peters, James Andya, 2009-11-11 Monoclonal antibodies represent one of the fastest growing areas of new drug development within the pharmaceutical industry. Several blockbuster products have been approved over the past several years including Rituxan, Remicade, Avastin, Humira, and Herceptin. In addition, over 300 new drugs are currently in clinical trials. With both large, established biotechnology companies and small start-ups involved in the development of this important class of molecules, monoclonal antibodies products will become increasingly prevalent over the next decade. Recently the regulatory review of monoclonal antibodies has been moved from Center for Biologics and Research to the Center for Drug Evaluation and Research (CDER) division of the US Food and Drug Administration. It is anticipated that CDER will expect a certain minimal amount of data to be provided as more of these products move through the regulatory pipeline. Current Trends in Monoclonal Antibody Development and Manufacturing will provide readers with an understanding of what is currently being done in the industry to develop, manufacture, and release monoclonal antibody products and what will be required for a successful regulatory submission. |
| catalent 483: LexisNexis Corporate Affiliations , 2008 |
| catalent 483: Dietary Reference Intakes for Calcium, Phosphorus, Magnesium, Vitamin D, and Fluoride Institute of Medicine, Food and Nutrition Board, Standing Committee on the Scientific Evaluation of Dietary Reference Intakes, 1999-10-17 Since 1941, Recommended Dietary Allowances (RDAs) has been recognized as the most authoritative source of information on nutrient levels for healthy people. Since publication of the 10th edition in 1989, there has been rising awareness of the impact of nutrition on chronic disease. In light of new research findings and a growing public focus on nutrition and health, the expert panel responsible for formulation RDAs reviewed and expanded its approachâ€the result: Dietary Reference Intakes. This new series of references greatly extends the scope and application of previous nutrient guidelines. For each nutrient the book presents what is known about how the nutrient functions in the human body, what the best method is to determine its requirements, which factors (caffeine or exercise, for example) may affect how it works, and how the nutrient may be related to chronic disease. The first volume of Dietary Reference Intakes includes calcium, phosphorus, magnesium, vitamin D, and fluoride. The second book in the series presents information about thiamin, riboflavin, niacin, vitamin B6, folate, vitamin B12, pantothenic acid, biotin, and choline. Based on analysis of nutrient metabolism in humans and data on intakes in the U.S. population, the committee recommends intakes for each age groupâ€from the first days of life through childhood, sexual maturity, midlife, and the later years. Recommendations for pregnancy and lactation also are made, and the book identifies when intake of a nutrient may be too much. Representing a new paradigm for the nutrition community, Dietary Reference Intakes encompasses: Estimated Average Requirements (EARs). These are used to set Recommended Dietary Allowances. Recommended Dietary Allowances (RDAs). Intakes that meet the RDA are likely to meet the nutrient requirement of nearly all individuals in a life-stage and gender group. Adequate Intakes (AIs). These are used instead of RDAs when an EAR cannot be calculated. Both the RDA and the AI may be used as goals for individual intake. Tolerable Upper Intake Levels (ULs). Intakes below the UL are unlikely to pose risks of adverse health effects in healthy people. This new framework encompasses both essential nutrients and other food components thought to pay a role in health, such as dietary fiber. It incorporates functional endpoints and examines the relationship between dose and response in determining adequacy and the hazards of excess intake for each nutrient. |
| catalent 483: Antibody-Drug Conjugates Jeffrey Wang, Wei-Chiang Shen, Jennica L. Zaro, 2015-03-05 This authoritative volume provides a holistic picture of antibody-drug conjugates (ADCs). Fourteen comprehensive chapters are divided into six sections including an introduction to ADCs, the ADC construct, development issues, landscape, IP and pharmacoeconomics, case studies, and the future of the field. The book examines everything from the selection of the antibody, the drug, and the linker to a discussion of developmental issues such as formulations, bio-analysis, pharmacokinetic-pharmacodynamic relationships, and toxicological and regulatory challenges. It also explores pharmacoecomonics and intellectual properties, including recently issued patents and the cost analysis of drug therapy. Case studies are presented for the three ADCs that have received FDA approval: gemtuzumab ozogamicin (Mylotarg®), Brentuximab vedotin (Adcetris®), and ado-trastuzumab emtansine (Kadcyla®), as well as an ADC in late-stage clinical trials, glembatumumab vedotin (CDX-011). Finally, the volume presents a perspective by the editors on the future directions of ADC development and clinical applications. Antibody-Drug Conjugates is a practical and systematic resource for scientists, professors, and students interested in expanding their knowledge of cutting-edge research in this exciting field. |
| catalent 483: The Phone Book Telkom (Firm : South Africa), 2004 |
| catalent 483: Hoover's Handbook of Private Companies 2010 Hoover's Business Press, 2010 Hoover's Handbook of Private Companies covers 900 nonpublic U.S. enterprises including large industrial and service corporations. |
| catalent 483: Long Acting Animal Health Drug Products Michael J. Rathbone, Arlene McDowell, 2012-10-11 Long acting veterinary formulations play a significant role in animal health, production and reproduction within the animal health industry. Such technologies offer beneficial advantages to the veterinarian, farmer and pet owner. These advantages have resulted in them growing in popularity in recent years. The pharmaceutical scientist is faced with many challenges when innovating new products in this demanding field of controlled release. This book provides the reader with a comprehensive guide on the theories, applications, and challenges associated with the design and development of long acting veterinary formulations. The authoritative chapters of the book are written by some of the leading experts in the field. The book covers a wide scope of areas including the market influences, preformulation, biopharmaceutics, in vitro drug release testing and specification setting to name but a few. It also provides a detailed overview of the major technological advances made in this area. As a result this book covers everything a formulation scientist in industry or academia, or a student needs to know about this unique drug delivery field to advance health, production and reproduction treatment options and benefits for animals worldwide. |
| catalent 483: D&B Reference Book of Corporate Managements , 2009 |
| catalent 483: Complexity and Criticality Kim Christensen, Nicholas R. Moloney, 2005 This book provides a challenging and stimulating introduction to the contemporary topics of complexity and criticality, and explores their common basis of scale invariance, a central unifying theme of the book.Criticality refers to the behaviour of extended systems at a phase transition where scale invariance prevails. The many constituent microscopic parts bring about macroscopic phenomena that cannot be understood by considering a single part alone. The phenomenology of phase transitions is introduced by considering percolation, a simple model with a purely geometrical phase transition, thus enabling the reader to become intuitively familiar with concepts such as scale invariance and renormalisation. The Ising model is then introduced, which captures a thermodynamic phase transition from a disordered to an ordered system as the temperature is lowered in zero external field. By emphasising analogies between percolation and the Ising model, the reader's intuition of phase transitions is developed so that the underlying theoretical formalism may be appreciated fully. These equilibrium systems undergo a phase transition only if an external agent finely tunes certain external parameters to particular values.Besides fractals and phase transitions, there are many examples in Nature of the emergence of such complex behaviour in slowly driven non-equilibrium systems: earthquakes in seismic systems, avalanches in granular media and rainfall in the atmosphere. A class of non-equilibrium systems, not constrained by having to tune external parameters to obtain critical behaviour, is addressed in the framework of simple models, revealing that the repeated application of simple rules may spontaneously give rise to emergent complex behaviour not encoded in the rules themselves. The common basis of complexity and criticality is identified and applied to a range of non-equilibrium systems. Finally, the reader is invited to speculate whether self-organisation in non-equilibrium systems might be a unifying concept for disparate fields such as statistical mechanics, geophysics and atmospheric physics.Visit http: //www.complexityandcriticality.com for animations for the models in the book (available for Windows and Linux), solutions to exercises, as well as a list with corrections. |
| catalent 483: Antioxidant Activity of Polyphenolic Plant Extracts Dimitrios Stagos, 2021-03-19 “Antioxidant Activity of Polyphenolic Plant Extracts” is a collection of scientific articles regarding polyphenols, that is, substances occurring naturally in plants and exhibiting many beneficial effects on human health. Among polyphenols’ interesting biological properties, their antioxidant activity is considered the most important. This book brings together experts from different research fields on topics related to polyphenols, such as their isolation and purification, assessment of their antioxidant activity, prevention from oxidative stress-induced diseases and use as food additives. The polyphenols used in the present studies are derived from a great variety of plants, ranging from well-known species to rare ones that are only found in specific regions. Moreover, some of the studies provide evidence that polyphenols may be used for the prevention and treatment of common diseases such as diabetes mellitus, Alzheimers’ disease, cardiovascular and intestinal diseases. Importantly, in several of the studies “green extraction methods” for the isolation of polyphenols were developed using modern technologies, where few or no organic solvents were used, in order to minimize environmental and health impacts. |
| catalent 483: D and B Million Dollar Directory , 2011 |
| catalent 483: America's Corporate Finance Directory , 1994 |
| catalent 483: Morgenblatt für gebildete Stände , 1821 |
| catalent 483: Pennsylvania Business Directory , 2008 |
| catalent 483: Studies on Experimental Models Samar Basu, Lars Wiklund, 2011-04-13 There is a widespread consensus that use of antioxidants as a therapeutic approach may counteract free radical mediated pathologies. However, the role of antioxidants in normal physiology and redox signaling is still in its infancy. Since oxidative stress is related to various diseases and pathologies, scientists are eager to study the disease in humans, but it is not always ethical to study all the aspects of the disease in humans. Thus, it becomes mandatory to study the disease process and the mechanisms behind it through experimental models which generally involve animals, in vitro/cell culture studies, primates and even humans to a certain extent. Studies on Experimental Models contains data on the experimental models or review of such models of oxidative stress in various diseases. It is structured into six sections, which are as follows: diabetes, cardiovascular, neurology, ocular diseases, toxicology/environmental and in vitro/tissue culture. Each section presents a sketch of models in humans, animals and in vitro methods. Taken together, they comprise a valuable reference for basic and clinical scientists, one aimed at contributing to the advancement of oxidative stress research using appropriate animal models. |
| catalent 483: Dictionary Catalog of the Research Libraries of the New York Public Library, 1911-1971 New York Public Library. Research Libraries, 1979 |
| catalent 483: The Chemistry of Sulphinic Acids, Esters and Their Derivatives Saul Patai, 1990 The series The Chemistry of Functional Groups is planned to cover, in each volume, all aspects of the chemistry of one of the important functional groups in organic chemistry. |
| catalent 483: Who Owns Whom , 2008 |
| catalent 483: Redox Proteomics Isabella Dalle-Donne, Andrea Scaloni, D. Allan Butterfield, 2006-08-11 Methodology and applications of redox proteomics The relatively new and rapidly changing field of redox proteomics has the potential to revolutionize how we diagnose disease, assess risks, determine prognoses, and target therapeutic strategies for people with inflammatory and aging-associated diseases. This collection brings together, in one comprehensive volume, a broad array of information and insights into normal and altered physiology, molecular mechanisms of disease states, and new applications of the rapidly evolving techniques of proteomics. Written by some of the finest investigators in this area, Redox Proteomics: From Protein Modifications to Cellular Dysfunction and Diseases examines the key topics of redox proteomics and redox control of cellular function, including: * The role of oxidized proteins in various disorders * Pioneering studies on the development of redox proteomics * Analytical methodologies for identification and structural characterization of proteins affected by oxidative/nitrosative modifications * The response and regulation of protein oxidation in different cell types * The pathological implications of protein oxidation for conditions, including asthma, cardiovascular disease, diabetes, preeclampsia, and Alzheimer's disease Distinguished by its in-depth discussions, balanced methodological approach, and emphasis on medical applications and diagnosis development, Redox Proteomics is a rich resource for all professionals with an interest in proteomics, cellular physiology and its alterations in disease states, and related fields. |
| catalent 483: D & B Million Dollar Directory , 2010 |
| catalent 483: Corporate Crime in the Pharmaceutical Industry (Routledge Revivals) John Braithwaite, 2013-10-08 First published in 1984, this book examines corporate crime in the pharmaceutical industry. Based on extensive research, including interviews with 131 senior executives of pharmaceutical companies in the United States, the United Kingdom, Australia, Mexico and Guatemala, the book is a major study of white-collar crime. Written in the 1980s, it covers topics such as international bribery and corruption, fraud in the testing of drugs and criminal negligence in the unsafe manufacturing of drugs. The author considers the implications of his findings for a range of strategies to control corporate crime, nationally and internationally. |
| catalent 483: Noncanonical Amino Acids Edward A. Lemke, 2018 |
| catalent 483: Advances in Pulmonary Drug Delivery Philip Chi Lip Kwok, Hak-Kim Chan, 2016-12-19 The respiratory tract has been used to deliver biologically active chemicals into the human body for centuries. However, the lungs are complex in their anatomy and physiology, which poses challenges to drug delivery. Inhaled formulations are generally more sophisticated than those for oral and parenteral administration. Pulmonary drug development is therefore a highly specialized area because of its many unique issues and challenges. Rapid progress is being made and offers novel solutions to existing treatment problems. Advances in Pulmonary Drug Delivery highlights the latest developments in this field. |
| catalent 483: Antibody-Drug Conjugates Laurent Ducry, 2016-08-23 Antibody-drug conjugates (ADCs) represent a promising therapeutic approach for cancer patients by combining the antigen-targeting specificity of monoclonal antibodies (mAbs) with the cytotoxic potency of chemotherapeutic drugs. In Antibody-Drug Conjugates, expert researchers provide detailed protocols for many of the key ADC techniques necessary for working in the field. These chapters and methodologies are aimed at the key tasks necessary to identify a suitable target, properly design the mAb, the linker and the payload, as well as to conjugate them in a reproducible and scalable fashion. Written in the highly successful Methods in Molecular BiologyTM format, these detailed chapters include the kind of practical implementation advice that guarantees quality results. Authoritative and timely, Antibody-Drug Conjugates aims to further drive ADC development and thus help toward improving cancer treatments of the future. |
| catalent 483: Securities Exchange Act of 1934 as Amended United States. Securities and Exchange Commission, 1934 |
| catalent 483: Skyward Vol. 1: My Low-G Life Joe Henderson, 2017 One day, gravity on Earth suddenly became a fraction of what it is now. Twenty years later, humanity has adapted to its new low-gravity reality. And to Willa Fowler, who was born just after G-day, it's pretty awesome. You can fly through the air! I mean, sure, you can also die if you jump too high. So you just don't jump too high. And maybe don't get mixed up in your dad's secret plan to bring gravity back that could get you killedÉ From writer JOE HENDERSON (showrunner of Fox's Lucifer) and artist LEE GARBETT (Lucifer, Loki: Agent of Asgard) comes the story of a young womanÕs journey to find her place in a world turned upside down. Collects SKYWARD #1-5 |
| catalent 483: The 15 Secrets the Taxman Doesn't Want You to Know Dwayne Daku, 2008-11-05 |
| catalent 483: Sport and Physical Culture in Canadian Society Jay Scherer, Jane Crossman, Brian Wilson, 2019-08-02 Social Dimensions of Canadian Sport and Physical Activity by Jane Crossman and Jay Scherer is an up-to-date, comprehensive overview of the relationship between sociological issues and sport, with a specific focus on the Canadian sports industry. KEY TOPICS: Sport and Physical Culture in Canadian Society;Thinking Sociologically: Sport, Physical Culture, and Critical Theory;Sport and Physical Culture in Historical Perspective;Sport and Social Stratification;Physical Culture, Sport, Ethnicity, and Race in Canada;Sex, Gender, and Sexuality;Youth Sport and Physical Culture;Deviance, Sport, and Physical Culture;Violence and Sport;Sport and Health;Sport, Media, and Ideology;Sport, Politics, and Policy;The Business of Sport;Globalization, Sport, and International Development;Sport and the Environment;Sport and the Future MARKET: Appropriate for Sociology of Sport courses. |
| catalent 483: Cell Death, Inflammation and Oxidative Stress in Neurodegenerative Diseases Anne Vejux, 2022-01-17 Neurogenerative diseases encompass very different pathologies, which can be demyelinating or nondemyelinating, but which have common mechanisms such as cell death, oxidative stress and inflammation. A better understanding of these mechanisms allows the search for biomarkers and targets for new therapies. This special issue brings together different data on Alzheimer's disease, Parkinson's disease, and multiple sclerosis, detailing the mechanisms of cell death (necroptosis, ferroptosis), oxidative stress and inflammation but also the possibilities of neuroprotection via 5 research articles and 6 review articles. The different reviews allow us to take stock of cell death, oxidative stress and neuroinflammation in the context of neurodegenerative diseases but also in relation to other pathologies where these processes are involved. |
| catalent 483: Long Acting Injections and Implants Jeremy C. Wright, Diane J. Burgess, 2012-01-29 Long acting injections and implants improve therapy, enhance patient compliance, improve dosing convenience, and are the most appropriate formulation choice for drugs that undergo extensive first pass metabolism or that exhibit poor oral bioavailability. An intriguing variety of technologies have been developed to provide long acting injections and implants. Many considerations need to go into the design of these systems in order to translate a concept from the lab bench to actual therapy for a patient. This book surveys and summarizes the field. Topics covered in Long Acting Injections and Implants include the historical development of the field, drugs, diseases and clinical applications for long acting injections and implants, anatomy and physiology for these systems, specific injectable technologies (including lipophilic solutions, aqueous suspensions, microspheres, liposomes, in situ forming depots and self-assembling lipid formulations), specific implantable technologies (including osmotic implants, drug eluting stents and microfabricated systems), peptide, protein and vaccine delivery, sterilization, drug release testing and regulatory aspects of long acting injections and implants. This volume provides essential information for experienced development professionals but was also written to be useful for scientists just beginning work in the field and for others who need an understanding of long acting injections and implants. This book will also be ideal as a graduate textbook. |
| catalent 483: Haines San Francisco City & Suburban Criss-cross Directory , 2006 |
| catalent 483: National Biennial RCRA Hazardous Waste Report (based on 1989 Data). , 1993 |
Leading Global CDMO for Pharma & Biotech | Catalent
Catalent is the #1 CDMO partner in helping pharmaceutical, biotech and consumer health innovators develop, deliver and supply superior products that improve people's lives.
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CATALENT CAREERS. DRUG DELIVERY INSTITUTE. INVESTORS. HIGH BUSINESS STANDARDS. As the global leader in enabling pharma, biotech, and consumer health …
Overview - Catalent
Catalent is dedicated to delivering unparalleled service to pharma, biotech, and consumer health customers, supporting product development, launch, and full life-cycle supply. With time-tested …
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Join the global drug development and delivery leader that puts patients at the center of our work every day. At Catalent, you are part of a growing international organization where our talented …
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私たちは、アジア太平洋および世界中で革新的なソフトジェル製剤の開発、配送、供給、および包括的な臨床製造、パッケージング、流通ソリューションを提供する世界的なリーダーです。
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Catalent is supported by our global reach, with facilities located worldwide enabling us to tailor a solution to fit your needs.
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Catalent é uma empresa internacional empolgante e em crescimento, com profissionais talentosos e apaixonados. Explore oportunidades globais recompensadoras para promover …
Novo Holdings to Acquire Catalent
Feb 5, 2024 · Catalent and Novo Holdings have entered into a merger agreement in an all-cash transaction that values Catalent at $16.5 billion. Catalent Stockholders to Receive $63.50 Per …
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We recognize talent is our most important asset. To explore a career with Catalent, visit our Careers Section to submit your resume.
Novo Holdings Completes Acquisition of Catalent
Catalent’s common stock has ceased trading and will be delisted from the New York Stock Exchange. Shortly following the completion of the transaction, Novo Nordisk A/S will acquire …
Leading Global CDMO for Pharma & Biotech | Catalent
Catalent is the #1 CDMO partner in helping pharmaceutical, biotech and consumer health innovators develop, deliver and supply superior products that improve people's lives.
About Us - Catalent
CATALENT CAREERS. DRUG DELIVERY INSTITUTE. INVESTORS. HIGH BUSINESS STANDARDS. As the global leader in enabling pharma, biotech, and consumer health …
Overview - Catalent
Catalent is dedicated to delivering unparalleled service to pharma, biotech, and consumer health customers, supporting product development, launch, and full life-cycle supply. With time-tested …
Careers - Catalent
Join the global drug development and delivery leader that puts patients at the center of our work every day. At Catalent, you are part of a growing international organization where our talented …
ホーム - Catalent Japan
私たちは、アジア太平洋および世界中で革新的なソフトジェル製剤の開発、配送、供給、および包括的な臨床製造、パッケージング、流通ソリューションを提供する世界的なリーダーです。
Our Locations - Catalent
Catalent is supported by our global reach, with facilities located worldwide enabling us to tailor a solution to fit your needs.
Home - Catalent Brasil
Catalent é uma empresa internacional empolgante e em crescimento, com profissionais talentosos e apaixonados. Explore oportunidades globais recompensadoras para promover …
Novo Holdings to Acquire Catalent
Feb 5, 2024 · Catalent and Novo Holdings have entered into a merger agreement in an all-cash transaction that values Catalent at $16.5 billion. Catalent Stockholders to Receive $63.50 Per …
Europe - Catalent
We recognize talent is our most important asset. To explore a career with Catalent, visit our Careers Section to submit your resume.
Novo Holdings Completes Acquisition of Catalent
Catalent’s common stock has ceased trading and will be delisted from the New York Stock Exchange. Shortly following the completion of the transaction, Novo Nordisk A/S will acquire …
