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| biological importance of stereochemistry: Foundations of Molecular Pharmacology J. B. Stenlake, 1979-01-01 |
| biological importance of stereochemistry: The Organic Chemistry of Medicinal Agents Adam Renslo, 2015-11-23 The most concise and streamlined textbook available on organic chemistry for the pharmacy student Organic Chemistry for Pharmacy is a textbook written specifically for the students taking the required Organic/Medical Pharmacy course. Using a building-block approach, the book delivers a basic, yet thorough discussion of the mode of action, therapeutic applications, and limitations of various pharmaceutical agents. Organic Chemistry for Pharmacy is especially written for students who have a limited background in chemistry. In order to make the learning/teaching experience as efficient as possible, Organic Chemistry for Pharmacy includes outstanding pedagogical features such as chapter outlines, chapter summaries, boxed “take away points”, quick-reference tables, and problems within each chapter. The focus and presentation of this text is particularly suited for Organic/Medical Pharmacy courses which are weighted heavily towards Organic, rather than Medical Pharmacy. |
| biological importance of stereochemistry: Stereochemistry - Workbook Karl-Heinz Hellwich, Carsten Siebert, 2006-10-11 This workbook in stereochemistry is designed for students, lecturers and scientists in chemistry, pharmacy, biology and medicine who deal with chiral chemical compounds and their properties. It serves as a supplement to textbooks and seminars and thus provides selected examples for students to practice the use of the conventions and terminology for the exact three-dimensional description of chemical compounds. It contains 191 problems with extended solutions. |
| biological importance of stereochemistry: Chirality in Drug Design and Development Indra K. Reddy, Reza Mehvar, 2004-03-15 Covering every essential element in the development of chiral products, this reference provides a solid overview of the formulation, biopharmaceutical characteristics, and regulatory issues impacting the production of these pharmaceuticals. It supports researchers as they evaluate the pharmacodynamic, pharmacokinetic, and toxicological characteristics of specific enantiomers and chiral drug compounds and addresses in one convenient reference all the major challenges pertaining to drug chirality that have been neglected in the literature. Chirality in Drug Design and Development collects the latest studies from an interdisciplinary team of experts on chiral drug design. |
| biological importance of stereochemistry: Principles and Applications of Stereochemistry Michael North, 2017-10-19 A thorough understanding of stereochemistry is essential for the comprehension of almost all aspects of modern organic chemistry. It is also of great significance in many biochemical and medicinal disciplines, since the stereoisomers of a compound can have dramatically different biological properties. This text explains how the different properties of stereoisomers of a compound arise, and what processes can be used to prepare and analyze stereoisomerically pure compounds. It also presents prominent coverage of the stereochemistry of inorganic and organometallic compounds, which is likely to increase in importance, as these compounds are used as symmetric catalysts in asymmetric synthesis. Modern stereochemical terminology is used throughout, although reference is also made to older terms which are still widely used. A set of problems at the end of each chapter aims to further the reader's understanding of how the content can be applied. The book is designed mainly as a textbook for undergraduate students and as a reference source for more advanced levels, but is also intended for academic and professional organic chemists. |
| biological importance of stereochemistry: Stereochemistry of Organic Compounds Ernest L. Eliel, Samuel H. Wilen, 1994-09-28 Stereochemistry of Organic Compounds The first fully referenced, comprehensive book on this subject in more than thirty years, Stereochemistry of Organic Compounds contains up-to-date coverage and insightful exposition of all important new concepts, developments, and tools in the rapidly advancing field of stereochemistry, including: * Asymmetric and diastereoselective synthesis * Conformational analysis * Properties of enantiomers and racemates * Separation and analysis of enantiomers and diastereoisomers * Developments in spectroscopy (including NMR), chromatography, and molecular mechanics as applied to stereochemistry * Prostereoisomerism * Conceptual foundations of stereochemistry, including terminology and symmetry concepts * Chiroptical properties Written by the leading authorities in the field, the text includes more than 4,000 references, 1,000 illustrations, and a glossary of stereochemical terms. |
| biological importance of stereochemistry: Basic Principles of Organic Chemistry John D. Roberts, Marjorie C. Caserio, 1977 Introduction what is organic chemistry all about?; Structural organic chemistry the shapes of molecules functional groups; Organic nomenclature; Alkanes; Stereoisomerism of organic molecules; Bonding in organic molecules atomic-orbital models; More on nomenclature compounds other than hydrocarbons; Nucleophilic substitution and elimination reactions; Separation and purification identification of organic compounds by spectroscopic techniques; Alkenes and alkynes. Ionic and radical addition reactions; Alkenes and alkynes; Oxidation and reduction reactions; Acidity or alkynes. |
| biological importance of stereochemistry: The Organic Chemistry of Drug Design and Drug Action Richard B. Silverman, 2012-12-02 Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes in the drug industry over the past decade, and includes chapter problems and other elements that make the book more useful for course instruction. - New edition includes new chapter problems and exercises to help students learn, plus extensive references and illustrations - Clearly presents an organic chemist's perspective of how drugs are designed and function, incorporating the extensive changes in the drug industry over the past ten years - Well-respected author has published over 200 articles, earned 21 patents, and invented a drug that is under consideration for commercialization |
| biological importance of stereochemistry: Introduction to Stereochemistry Andrew Clark, Russ Kitson, Nimesh Mistry, Paul Taylor, Matthew Taylor, Michael Lloyd, 2020-10-23 Stereochemistry is an important concept that often causes confusion amongst students when they learn it for the first time. In this book we deal with tricky concepts like conformation and configuration, how to represent them accurately and how to use the correct terms to describe them in both organic and inorganic chemistry. |
| biological importance of stereochemistry: Introduction to Theoretical Stereochemistry Vi͡acheslav Ivanovich Sokolov, 1991 First published in 1991. Routledge is an imprint of Taylor & Francis, an informa company. |
| biological importance of stereochemistry: Topics in Stereochemistry Ernest L. Eliel, Samuel H. Wilen, Norman L. Allinger, 2009-09-17 This seminal series, first edited by Ernest Eliel, responsible for some of the major advances in stereochemistry and the winner of the ACS Priestley Medal in 1996, provides coverage of the major developments of the field of stereochemistry. The scope of this series is broadly defined to encompass all fields of chemical and biological sciences that are founded on molecular and supramolecular interactions. Insofar as chemical, physical, and biological properties are determined by molecular shape and structure, the importance of stereochemistry is fundamental to and consequential for all natural sciences. Topics in Stereochemistry serves as a multidisciplinary series that enriches all of chemistry. Aimed at advanced students, university professors and teachers as well as researchers in pharmaceutical, agricultural, biotechnological, polymer, materials, and fine chemical industries, Topics in Stereochemistry publishes definitive and scholarly reviews in stereochemistry and has long been recognized as the gold standard reference work in this field. Covering the effect of chirality on all aspects of molecular interaction from the fundamental physical chemical properties of molecules and their molecular physics to the application of chirality in new areas such as its applications in materials science, Topics in Stereochemistry explores a wide variety of properties, both physical and chemical of isomers with a view to their applications in a number of disciplines from biochemistry to materials science. |
| biological importance of stereochemistry: Topics in Stereochemistry, Volume 19 Ernest L. Eliel, Samuel H. Wilen, Norman L. Allinger, 2009-09-17 This seminal series, first edited by Ernest Eliel, responsible for some of the major advances in stereochemistry and the winner of the ACS Priestley Medal in 1996, provides coverage of the major developments of the field of stereochemistry. The scope of this series is broadly defined to encompass all fields of chemical and biological sciences that are founded on molecular and supramolecular interactions. Insofar as chemical, physical, and biological properties are determined by molecular shape and structure, the importance of stereochemistry is fundamental to and consequential for all natural sciences. Topics in Stereochemistry serves as a multidisciplinary series that enriches all of chemistry. Aimed at advanced students, university professors and teachers as well as researchers in pharmaceutical, agricultural, biotechnological, polymer, materials, and fine chemical industries, Topics in Stereochemistry publishes definitive and scholarly reviews in stereochemistry and has long been recognized as the gold standard reference work in this field. Covering the effect of chirality on all aspects of molecular interaction from the fundamental physical chemical properties of molecules and their molecular physics to the application of chirality in new areas such as its applications in materials science, Topics in Stereochemistry explores a wide variety of properties, both physical and chemical of isomers with a view to their applications in a number of disciplines from biochemistry to materials science. |
| biological importance of stereochemistry: Materials-Chirality Mark M. Green, R. J. M. Nolte, E. W. Meijer, 2004-05-07 Dieser Sonderband der Reihe Topics in Stereochemistry beschäftigt sich mit der Chiralität von Werkstoffen und der Bedeutung der Stereochemie für bestimmte Polymere, Flüssigkristalle und andere spezielle Materialien. Die Grundlage dafür bilden die ausführlich dargestellten Prinzipien der organischen Stereochemie. Das aktuellste derzeit erhältliche Buch zur Chiralität! |
| biological importance of stereochemistry: Stereochemistry , 1982-01-01 Stereochemistry |
| biological importance of stereochemistry: Thioredoxin and Glutaredoxin Systems Jean-Pierre Jacquot, Mirko Zaffagnini, 2019-05-10 This Special Issue features recent data concerning thioredoxins and glutaredoxins from various biological systems, including bacteria, mammals, and plants. Four of the sixteen articles are review papers that deal with the regulation of development of the effect of hydrogen peroxide and the interactions between oxidants and reductants, the description of methionine sulfoxide reductases, detoxification enzymes that require thioredoxin or glutaredoxin, and the response of plants to cold stress, respectively. This is followed by eleven research articles that focus on a reductant of thioredoxin in bacteria, a thioredoxin reductase, and a variety of plant and bacterial thioredoxins, including the m, f, o, and h isoforms and their targets. Various parameters are studied, including genetic, structural, and physiological properties of these systems. The redox regulation of monodehydroascorbate reductase, aminolevulinic acid dehydratase, and cytosolic isocitrate dehydrogenase could have very important consequences in plant metabolism. Also, the properties of the mitochondrial o-type thioredoxins and their unexpected capacity to bind iron–sulfur center (ISC) structures open new developments concerning the redox mitochondrial function and possibly ISC assembly in mitochondria. The final paper discusses interesting biotechnological applications of thioredoxin for breadmaking. |
| biological importance of stereochemistry: Dynamic Stereochemistry of Chiral Compounds Christian Wolf, 2008 A comprehensive overview of fundamental concepts of asymmetric synthesis along with in-depth discussion. Recent developments that address important synthetic challenges are presented and highlighted with hundreds of examples. |
| biological importance of stereochemistry: Chemistry of Plant Natural Products Sunil Kumar Talapatra, Bani Talapatra, 2015-03-20 Aimed at advanced undergraduate and graduate students and researchers working with natural products, Professors Sunil and Bani Talapatra provide a highly accessible compilation describing all aspects of plant natural products. Beginning with a general introduction to set the context, the authors then go on to carefully detail nomenclature, occurrence, isolation, detection, structure elucidation (by both degradation and spectroscopic techniques) stereochemistry, conformation, synthesis, biosynthesis, biological activity and commercial applications of the most important natural products of plant origin. Each chapter also includes detailed references (with titles) and a list of recommended books for additional study making this outstanding treatise a useful resource for teachers of chemistry and researchers working in universities, research institutes and industry. |
| biological importance of stereochemistry: Carbohydrate Chemistry, Biology and Medical Applications Hari G. Garg, Mary K. Cowman, Charles A. Hales, 2011-09-06 The finding by Emil Fischer that glucose and fructose on treatment with phenylhydrazine gave the identical osazone led him to the elucidation of stereochemistry of carbohydrates. Since then, progress in the field of carbohydrates has been amazing with the unraveling their basic structure, biosynthesis, immunology, functions, and clinical uses, for pure carbohydrates and for protein-linked carbohydrates (glycoproteins and proteoglycans). The chapters in Carbohydrate Chemistry, Biology and Medical Applications present a logical sequence leading from the chemistry and biochemistry of carbohydrates, followed by their role in various pathological conditions, to carbohydrates as potential therapeutic and diagnostic agents. This book offers a detailed panoramic review of the chemistry and biology of carbohydrates for chemists, biologists and health professionals. Each chapter is authored by contributors expert in the particular area of research. - Explains how carbohydrates are important to life - Details the chemistry, biology and medical aspects of carbohydrates - Interdisciplinary and international team of authors |
| biological importance of stereochemistry: Stereochemical and Stereophysical Behaviour of Macrocycles Bozzano G Luisa, 2012-12-02 Stereochemical and Stereophysical Behavior of Macrocycles deals with the stereochemical and stereophysical properties of macrocyclic ligands and their coordination compounds. More specifically, the stereochemistry of metallic macrocyclics is discussed, along with the relationship between the thermodynamics and stereochemistry of macrocyclics and cryptates. The stereochemical aspects of the macrocycles of second and third row transition elements are also examined. Comprised of three chapters, this volume begins with an introduction to the stereochemistry of metallic macrocyclics as well as their structure, together with the conformation of their chemical rings and the steric effects of their coordination geometry. The next chapter considers the relationship between the thermodynamics and stereochemistry of macrocyclics and cryptates, with particular reference to the macrocyclic and cryptate effect. Cation-ligand interactions and solvent effects upon complex formation are described, along with macrocyclic and macrobicyclic ligands having different donor atoms. The final chapter is devoted to the stereochemical aspects of the macrocycles of transition metal ions, with additional comments on the stereochemistry of copper and nickel in unusual oxidation states. This book will be of interest to inorganic chemists. |
| biological importance of stereochemistry: Topics in Stereochemistry Ernest L. Eliel, Samuel H. Wilen, Norman L. Allinger, 2009-09-17 This seminal series, first edited by Ernest Eliel, responsible for some of the major advances in stereochemistry and the winner of the ACS Priestley Medal in 1996, provides coverage of the major developments of the field of stereochemistry. The scope of this series is broadly defined to encompass all fields of chemical and biological sciences that are founded on molecular and supramolecular interactions. Insofar as chemical, physical, and biological properties are determined by molecular shape and structure, the importance of stereochemistry is fundamental to and consequential for all natural sciences. Topics in Stereochemistry serves as a multidisciplinary series that enriches all of chemistry. Aimed at advanced students, university professors and teachers as well as researchers in pharmaceutical, agricultural, biotechnological, polymer, materials, and fine chemical industries, Topics in Stereochemistry publishes definitive and scholarly reviews in stereochemistry and has long been recognized as the gold standard reference work in this field. Covering the effect of chirality on all aspects of molecular interaction from the fundamental physical chemical properties of molecules and their molecular physics to the application of chirality in new areas such as its applications in materials science, Topics in Stereochemistry explores a wide variety of properties, both physical and chemical of isomers with a view to their applications in a number of disciplines from biochemistry to materials science. |
| biological importance of stereochemistry: Peroxidases in Chemistry and Biology Johannes Everse, Matthew B. Grisham, Kathleen E. Everse, 1990-11-20 The Peroxidases in Chemistry and Biology series provides up-to-date information on a wide range of developments in the field of Peroxidases, methods and applications. This is Volume 1 originally published in 1990. |
| biological importance of stereochemistry: Techniques and Topics in Bioinorganic Chemistry C.A. McAuliffe, 1975-06-18 |
| biological importance of stereochemistry: Chirality and Biological Activity Hartmut Frank, Bo Holmstedt, Bernard Testa, 1990 Reporting on the latest advances in molecular asymmetry, it explores the development of stereochemical analysis and its applications to the biosciences. Applications to pharmacology and therapeutics, food and beverage chemistry, the study of pesticides and other zenobiotics are also covered. Chapters examine the molecular principles of chiral recognition and biological selectivity and discuss stereoselectivity in drug action and metabolism. Some of the specific issues covered include: gas and liquid chromatography of enantiomers on chiral stationary phases; stereochemical assays of chiral drugs; pyrethroid isomers; configurational modification of peptide hormones; chiral fruit flavors; and human pharmacokinetics of enantiomers administered as racemates. |
| biological importance of stereochemistry: Strigolactones - Biology and Applications Hinanit Koltai, Cristina Prandi, 2019-04-02 This book describes the exciting biology and chemistry of strigolactones. Outgrowth of shoot branches? Development of lateral roots? Interactions with beneficial microorganisms? Avoiding parasitic plants? Responding to drought conditions? These important “decisions” that plants make are all regulated by a group of hormones called strigolactones. The latest research has yielded a number of new biological concepts, such as a redefinition of plant hormones and their crosstalk, new functional diversity of receptors, hormonal “smoke and mirrors,” core signaling pathways, and even phloem transport of receptor proteins. Another important aspect of strigolactones is the related synthetic chemistry, which could pave the way for a variety of potential applications in agriculture and medicine. The book explains in detail the role that strigolactones play in plant development, and addresses the interaction of plants with soil biota and abiotic stress conditions, prospects of strigolactone biochemistry and evolution, and chemical synthesis of natural strigolactones and analogs, together with their potential applications. Including a glossary and end-of-chapter synopses to aid in comprehension, it offers a valuable asset for teachers, lecturers and (post-) graduate students in biology, agronomy and related areas.. |
| biological importance of stereochemistry: Organic Stereochemistry Hua-Jie Zhu, 2015-04-28 Adopting a novel approach to the topic by combining theoretical knowledge and practical results, this book presents the most popular and useful computational and experimental methods applied for studying the stereochemistry of chemical reactions and compounds. The text is clearly divided into three sections on fundamentals, spectroscopic and computational techniques, and applications in organic synthesis. The first part provides a brief introduction to the field of chirality and stereochemistry, while the second part covers the different methodologies, such as optical rotation, electronic circular dichroism, vibrational circular dicroism, and Raman spectroscopy. The third section then goes on to describe selective examples in organic synthesis, classified by reaction type, i.e. enantioselective, chemoselective and stereoselective reactions. A final chapter on total synthesis of natural products rounds off the book. A valuable reference for researchers in academia and industry working in the field of organic synthesis, computational chemistry, spectroscopy or medicinal chemistry. |
| biological importance of stereochemistry: Biochirality Pedro Cintas, 2014-07-08 Early History of the Recognition of Molecular Biochirality, by Joseph Gal, Pedro Cintas Synthesis and Chirality of Amino Acids Under Interstellar Conditions, by Chaitanya Giri, Fred Goesmann, Cornelia Meinert, Amanda C. Evans, Uwe J. Meierhenrich Chemical and Physical Models for the Emergence of Biological Homochirality, by son E. Hein, Dragos Gherase, Donna G. Blackmond Biomolecules at Interfaces: Chiral, Naturally, by Arántzazu González-Campo and David B. Amabilino Stochastic Mirror Symmetry Breaking: Theoretical Models and Simulation of Experiments, by Celia Blanco, David Hochberg Self-Assembly of Dendritic Dipeptides as a Model of Chiral Selection in Primitive Biological Systems, by Brad M. Rosen, Cécile Roche, Virgil Percec Chirality and Protein Biosynthesis, by Sindrila Dutta Banik, Nilashis Nandi |
| biological importance of stereochemistry: Research Awards Index , 1989 |
| biological importance of stereochemistry: March's Advanced Organic Chemistry Michael B. Smith, Jerry March, 2007-01-29 The Sixth Edition of a classic in organic chemistry continues its tradition of excellence Now in its sixth edition, March's Advanced Organic Chemistry remains the gold standard in organic chemistry. Throughout its six editions, students and chemists from around the world have relied on it as an essential resource for planning and executing synthetic reactions. The Sixth Edition brings the text completely current with the most recent organic reactions. In addition, the references have been updated to enable readers to find the latest primary and review literature with ease. New features include: More than 25,000 references to the literature to facilitate further research Revised mechanisms, where required, that explain concepts in clear modern terms Revisions and updates to each chapter to bring them all fully up to date with the latest reactions and discoveries A revised Appendix B to facilitate correlating chapter sections with synthetic transformations |
| biological importance of stereochemistry: Stereochemistry, Basic Concepts and Applications M. Nógrádi, 1981 |
| biological importance of stereochemistry: Natural Products James Ralph Hanson, 2003 Natural products are compounds that are produced by living systems and the secondary metabolites are those which give particular species their characteristic features. These natural products include polyketides, terpenoids, phenylpropanoids, alkaloids and antibiotics. The study of these natural products has played a major part in the development of organic and medicinal chemistry and we are now starting to understand the important ecological role that these compounds have. The aim of this book is to describe the major features of these compounds and the way in which chemical and physical methods have been used to establish their structures and then to show how these structures can be rationalised in biosynthetic terms. The first chapter describes the classes of natural product, their biological activity and isolation. Subsequent chapters attempt to link chemical and spectroscopic strategies in structure elucidation, contrasting the classical chemical strategies that were used in the past with modern spectroscopic methods. The final chapter describes the biosynthesis of natural products. The elucidation of the structures of natural products brings together many elements taught in courses on functional group chemistry, stereochemistry and elementary spectroscopy. This book will therefore be welcomed by lecturers and students of second-year chemistry courses. Ideal for the needs of undergraduate chemistry students, Tutorial Chemistry Texts is a major series consisting of short, single topic or modular texts concentrating on the fundamental areas of chemistry taught in undergraduate science courses. Each book provides a concise account of the basic principles underlying a given subject, embodying an independent-learning philosophy and including worked examples. |
| biological importance of stereochemistry: Essential Organic Chemistry, Global Edition Paula Yurkanis Bruice, 2015-09-14 For one-term courses in Organic Chemistry. A comprehensive, problem-solving approach for the brief Organic Chemistry course. Modern and thorough revisions to the streamlined, Essential Organic Chemistry focus on developing students’ problem solving and analytical reasoning skills throughout organic chemistry. Organised around reaction similarities and rich with contemporary biochemical connections, Bruice’s 3rd Edition discourages memorisation and encourages students to be mindful of the fundamental reasoning behind organic reactivity: electrophiles react with nucleophiles. Developed to support a diverse student audience studying organic chemistry for the first and only time, Essentials fosters an understanding of the principles of organic structure and reaction mechanisms, encourages skill development through new Tutorial Spreads and and emphasises bioorganic processes. Contemporary and rigorous, Essentials addresses the skills needed for the 2015 MCAT and serves both pre-med and biology majors. The full text downloaded to your computer With eBooks you can: search for key concepts, words and phrases make highlights and notes as you study share your notes with friends eBooks are downloaded to your computer and accessible either offline through the Bookshelf (available as a free download), available online and also via the iPad and Android apps. Upon purchase, you'll gain instant access to this eBook. Time limit The eBooks products do not have an expiry date. You will continue to access your digital ebook products whilst you have your Bookshelf installed. |
| biological importance of stereochemistry: Organic Chemistry Michael B. Smith, 2022-09-23 Based on the premise that many, if not most, reactions in organic chemistry can be explained by variations of fundamental acid–base concepts, Organic Chemistry: An Acid–Base Approach provides a framework for understanding the subject that goes beyond mere memorization. Using several techniques to develop a relational understanding, it helps students fully grasp the essential concepts at the root of organic chemistry. This new edition was rewritten largely with the feedback of students in mind and is also based on the author’s classroom experiences using the previous editions. Highlights of the Third Edition Include: Extensively revised chapters that improve the presentation of material. Features the contributions of more than 65 scientists, highlighting the diversity in organic chemistry. Features the current work of over 30 organic chemists, highlighting the diversity in organic chemistry. Many new reactions are featured that are important in modern organic chemistry. Video lectures are provided in a .mov format, accessible online as a ‘built-in’ ancillary for the book. The homework is available online, gratis to all users. The third edition of Organic Chemistry: An Acid–Base Approach constitutes a significant improvement upon a unique introductory technique to organic chemistry. The reactions and mechanisms it covers are the most fundamental concepts in organic chemistry that are applied to industry, biological chemistry, biochemistry, molecular biology, and pharmacy. Using an illustrated conceptual approach rather than presenting sets of principles and theories to memorize, it gives students a more concrete understanding of the material. |
| biological importance of stereochemistry: Pharmacotherapy Casebook Terry L. Schwinghammer, 2005 This casebook is designed to help students develop the skills required to identify and resolve drug therapy problems through the use of patient case studies. |
| biological importance of stereochemistry: Chemistry for Pharmacy Students Professor Satyajit D. Sarker, Lutfun Nahar, 2013-05-28 This book has succeeded in covering the basic chemistry essentials required by the pharmaceutical science student... the undergraduate reader, be they chemist, biologist or pharmacist will find this an interesting and valuable read. –Journal of Chemical Biology, May 2009 Chemistry for Pharmacy Students is a student-friendly introduction to the key areas of chemistry required by all pharmacy and pharmaceutical science students. The book provides a comprehensive overview of the various areas of general, organic and natural products chemistry (in relation to drug molecules). Clearly structured to enhance student understanding, the book is divided into six clear sections. The book opens with an overview of general aspects of chemistry and their importance to modern life, with particular emphasis on medicinal applications. The text then moves on to a discussion of the concepts of atomic structure and bonding and the fundamentals of stereochemistry and their significance to pharmacy- in relation to drug action and toxicity. Various aspects of aliphatic, aromatic and heterocyclic chemistry and their pharmaceutical importance are then covered with final chapters looking at organic reactions and their applications to drug discovery and development and natural products chemistry. accessible introduction to the key areas of chemistry required for all pharmacy degree courses student-friendly and written at a level suitable for non-chemistry students includes learning objectives at the beginning of each chapter focuses on the physical properties and actions of drug molecules |
| biological importance of stereochemistry: The Biology of Cholesterol and Related Steroids N. B. Myant, 1981 The Biology of Cholesterol and Related Steroids ... |
| biological importance of stereochemistry: Basic Concepts in Medicinal Chemistry Marc W. Harrold, Robin M. Zavod, 2018 This updated and expanded edition of the popular textbook, Basic Concepts in Medicinal Chemistry, has been enhanced with new subject material, numerous self-assessment tools and special features to advance and strengthen the learning process. Designed to help students incrementally build their knowledge of fundamental concepts of medicinal chemistry and their applications to therapeutic decisions, it is progressively organized. The text is also enhanced to make potentially confusing concepts easier to understand. Numerous examples and review questions further reinforce learning and analytical skills--Publisher's description. |
| biological importance of stereochemistry: Subject Index of Current Research Grants and Contracts Administered by the National Institute of General Medical Sciences National Institute of General Medical Sciences (U.S.). Division of Research Grants, 1976 |
| biological importance of stereochemistry: Sustainable Chemistry in Action Gautami Devar, 2025-01-03 Discover the path to a healthier life through the principles of sustainable chemistry. Our book, Sustainable Chemistry in Action, delves into the mysteries of chemicals and their impact on human health and the environment. We expose the harmful effects of industrial chemicals and highlight the importance of adopting greener practices. Environmentalists have long raised alarms about these invisible killers, prompting governments and chemists to seek greener solutions. This book explores the development of environmentally friendly products, such as toiletries and detergents, replacing harmful substances with safer alternatives. We discuss the pervasive issue of plastic pollution and its devastating effects on ecosystems. Awareness and education are crucial in promoting sustainable practices, and this book aims to enlighten readers on the importance of green chemistry. Chemists are leading the way by utilizing renewable resources, contributing to a healthier and more sustainable world. |
| biological importance of stereochemistry: Research Grants Index National Institutes of Health (U.S.). Division of Research Grants, 1975 |
| biological importance of stereochemistry: Stereochemistry of Organic Compounds V.K. Ahluwalia, 2023-01-06 This textbook provides a simple approach to understand the various complex aspects of stereochemistry. It deals with basic static stereochemistry and gives an overview of the different isomeric forms and nomenclatures. With simple writing style and many examples, this book covers the topics such as stereochemistry of hydrocarbons, alkenes, cycloalkenes, optically active compounds, trivalent carbon, fused, bridged and caged rings and related compounds. This textbook also covers the additional topics such as optical rotatory dispersion and circular dichroism, steroechemistry of elimination reactions, substitution reactions, rearrangement reactions and pericyclic reactions. The book includes pedagogical features like end-of-chapter problems and key concepts to help students in self-learning. The textbook is extremely useful for the senior undergraduate and postgraduate students pursuing course in chemistry, especially organic chemistry. Besides, this book will also be a useful reference book for professionals working in various chemical industries, biotechnology, bioscience and pharmacy. |
Biologicals - World Health Organization (WHO)
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Dec 21, 2020 · This fourth edition of the manual builds on the risk assessment framework introduced in the third edition. A thorough, evidence-based and transparent assessment of the …
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Biologicals - World Health Organization (WHO)
4 days ago · Biological therapeutics, also referred to as Biologicals, are those class of medicines which are grown and then purified from large-scale cell cultures of bacteria or yeast, or plant or …
International Day for Biological Diversity: Harmony between …
May 19, 2025 · This year’s International Day for Biological Diversity, on Thursday, 22 May 2025, highlights the inherent connections between people and the natural world through the theme, …
WHO good manufacturing practices for biological products
present in raw materials, media, biological substances, intermediates or finished products. Regarded as contamination when the level and/or type exceed specifications. Biohazard: any …
Laboratory biosafety manual, 4th edition - World Health …
Dec 21, 2020 · This fourth edition of the manual builds on the risk assessment framework introduced in the third edition. A thorough, evidence-based and transparent assessment of the …
Biological weapons - World Health Organization (WHO)
Sep 6, 2018 · The use of biological agents is a serious concern, and the risk of using these agents in a terrorist attack is thought to be increasing. Preparedness WHO focuses on the possible …
Determinants of health
Oct 4, 2024 · Food and water are the major sources of exposure to both chemical and biological hazards. They impose a substantial health risk to consumers and economic burdens on …
Mental health - World Health Organization (WHO)
Jun 17, 2022 · Individual psychological and biological factors such as emotional skills, substance use and genetics can make people more vulnerable to mental health problems. Exposure to …
Biotherapeutic products - World Health Organization (WHO)
Biotechnology describes biological processes that have been manipulated or modified in some way through modern science. A major industrial application of biotechnology is in the …
Ionizing radiation and health effects - World Health Organization …
Jul 27, 2023 · WHO fact sheet on ionizing radiation, health effects and protective measures: includes key facts, definition, sources, type of exposure, health effects, nuclear emergencies, …
Health products policy and standards - World Health Organization …
The catalogue of international reference standards for biological products is updated following the Expert Committee on Biological Standardization meetings. See below for the catalogue, listed …
