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| bioprocess engineering lecture notes: Advances in Bioprocess Engineering and Technology Doraiswami Ramkrishna, Subhabrata Sengupta, Sudipta Dey Bandyopadhyay, Avijit Ghosh, 2020-09-29 This book presents the select peer-reviewed proceedings of the International Conference on Advances in Bioprocess Engineering and Technology (ICABET 2020). The book covers all aspects of bioprocesses, especially related to fermentation technology, food technology, environmental biotechnology, and sustainable energy. Along with this primary theme, the focus is on recent advances in bioprocessing research such as biosensors, micro-reactors, novel separation techniques, bioprocess control, bio-safety, advanced techniques for waste to wealth generation, and nanobiotechnology. This contents are divided according to the major themes of the conference: (i) Fermentation Technology and Bioreactor, (ii) Food Pharmaceuticals and Health care, (iii) Environment and Agriculture, and (iv) Sustainable Energy. This book is intended to help students, researchers, and industry professionals acquire knowledge on innovative technologies and recent advancements in the field of bioprocess engineering and technology. |
| bioprocess engineering lecture notes: Bioprocess Engineering Principles Pauline M. Doran, 1995-04-03 The emergence and refinement of techniques in molecular biology has changed our perceptions of medicine, agriculture and environmental management. Scientific breakthroughs in gene expression, protein engineering and cell fusion are being translated by a strengthening biotechnology industry into revolutionary new products and services. Many a student has been enticed by the promise of biotechnology and the excitement of being near the cutting edge of scientific advancement. However, graduates trained in molecular biology and cell manipulation soon realise that these techniques are only part of the picture. Reaping the full benefits of biotechnology requires manufacturing capability involving the large-scale processing of biological material. Increasingly, biotechnologists are being employed by companies to work in co-operation with chemical engineers to achieve pragmatic commercial goals. For many years aspects of biochemistry and molecular genetics have been included in chemical engineering curricula, yet there has been little attempt until recently to teach aspects of engineering applicable to process design to biotechnologists.This textbook is the first to present the principles of bioprocess engineering in a way that is accessible to biological scientists. Other texts on bioprocess engineering currently available assume that the reader already has engineering training. On the other hand, chemical engineering textbooks do not consider examples from bioprocessing, and are written almost exclusively with the petroleum and chemical industries in mind. This publication explains process analysis from an engineering point of view, but refers exclusively to the treatment of biological systems. Over 170 problems and worked examples encompass a wide range of applications, including recombinant cells, plant and animal cell cultures, immobilised catalysts as well as traditional fermentation systems.* * First book to present the principles of bioprocess engineering in a way that is accessible to biological scientists* Explains process analysis from an engineering point of view, but uses worked examples relating to biological systems* Comprehensive, single-authored* 170 problems and worked examples encompass a wide range of applications, involving recombinant plant and animal cell cultures, immobilized catalysts, and traditional fermentation systems* 13 chapters, organized according to engineering sub-disciplines, are groupled in four sections - Introduction, Material and Energy Balances, Physical Processes, and Reactions and Reactors* Each chapter includes a set of problems and exercises for the student, key references, and a list of suggestions for further reading* Includes useful appendices, detailing conversion factors, physical and chemical property data, steam tables, mathematical rules, and a list of symbols used* Suitable for course adoption - follows closely curricula used on most bioprocessing and process biotechnology courses at senior undergraduate and graduate levels. |
| bioprocess engineering lecture notes: Bioprocess engineering course notes Marin Berovič, Patricia Kieran, Alvin W. Nienow, 2005 |
| bioprocess engineering lecture notes: Advances in Bioprocess Engineering and Technology Doraiswami Ramkrishna, Subhabrata Sengupta, Sudipta Dey Bandyopadhyay, Avijit Ghosh, 2021-10-01 This book presents the select peer-reviewed proceedings of the International Conference on Advances in Bioprocess Engineering and Technology (ICABET 2020). The book covers all aspects of bioprocesses, especially related to fermentation technology, food technology, environmental biotechnology, and sustainable energy. Along with this primary theme, the focus is on recent advances in bioprocessing research such as biosensors, micro-reactors, novel separation techniques, bioprocess control, bio-safety, advanced techniques for waste to wealth generation, and nanobiotechnology. This contents are divided according to the major themes of the conference: (i) Fermentation Technology and Bioreactor, (ii) Food Pharmaceuticals and Health care, (iii) Environment and Agriculture, and (iv) Sustainable Energy. This book is intended to help students, researchers, and industry professionals acquire knowledge on innovative technologies and recent advancements in the field of bioprocess engineering and technology. |
| bioprocess engineering lecture notes: Process Biotechnology S. N. Mukhopadhyay, 2012-01-01 Rapid progress has been made in the discipline of biochemical engineering and biotechnology for bioprocess development during the last 50 years. Process Biotechnology: theory and practice has been written with the consideration that tutorial practice is as important as understanding the subject theoretically. This book is an introductory tutorial book involving multidisciplinary principles. Principal innovations that have been made in biosystem-related developments have been emphasized through tutorials in this book. The first few chapters cover theoretical aspects of biochemical and chemical engineering concerns in biotechnological advances in a concise manner. The rest have been dedicated to the tutorial aspects of this multidisciplinary subject. This book covers biological, ecological, chemical, and biochemical engineering topics related to the subject. It provides much needed theory-based solved numerical problems for practice in quantitative evaluation of various parameters relevant to process biotechnology. It will be useful for students who would like to further their careers as biotechnologists and can be used as a self-study text for practicing engineers, biotechnologists, microbiologists, and scientists involved in bioprocessing research and other related fields. |
| bioprocess engineering lecture notes: Bioprocess Parameter Control A. Fiechter, 1984-12-31 No detailed description available for Bioprocess Parameter Control. |
| bioprocess engineering lecture notes: New Products and New Areas of Bioprocess Engineering , 2003-06-30 Today, ergot alkaloids have found widespread clinical use and more than 50 formulations contain natural or semisynthetic ergot alkaloids. They are used in the treatment of uterine atonia, postpartum bleeding, migraine, orthostatic circulatory disturbances, senile cerebral insufficiency, hypertension, hyp- prolactinemia, acromegaly, and Parkinsonism. Recently, new therapeutic - plications have emerged, e.g., against schizophrenia and for therapeutic usage based on newly discovered antibacterial and cytostatic effects, immunomodu- tory and hypolipemic activity. The broad physiological effects of ergot alkaloids are based mostly on their interactions with neurotransmitter receptors on the cells. The presence of hidden structures'' resembling some important neu- humoral mediators (e.g., noradrenaline, serotonin, dopamine) in the molecules of ergot alkaloids could explain their interactions with these receptors [1]. Ergot alkaloids are produced by the filamentous fungi of the genus, Claviceps (e.g., Claviceps purpurea - Ergot, Mutterkorn). On the industrial scale these alkaloids were produced mostly by parasitic cultivation (field production of the ergot) till the end of the 1970s. Today this uneconomic method has been - placed by submerged fermentation. Even after a century of research on ergot alkaloids the search still continues for new, more potent and more selective ergot alkaloid derivatives |
| bioprocess engineering lecture notes: Computational Intelligence Techniques for Bioprocess Modelling, Supervision and Control Maria Carmo Nicoletti, 2009-07-09 Computational Intelligence (CI) and Bioprocess are well-established research areas which have much to offer each other. Under the perspective of the CI area, Biop- cess can be considered a vast application area with a growing number of complex and challenging tasks to be dealt with, whose solutions can contribute to boosting the development of new intelligent techniques as well as to help the refinement and s- cialization of many of the already existing techniques. Under the perspective of the Bioprocess area, CI can be considered a useful repertoire of theories, methods and techniques that can contribute and offer interesting alternative approaches for solving many of its problems, particularly those hard to solve using conventional techniques. Although throughout the past years CI and Bioprocess areas have accumulated substantial specific knowledge and progress has been quick and with a high degree of success, we believe there is still a long way to go in order to use the potentialities of the available CI techniques and knowledge at their full extent, as tools for supporting problem solving in bioprocesses. One of the reasons is the fact that both areas have progressed steadily and have been continuously accumulating and refining specific knowledge; another reason is the high level of technical expertise demanded by each of them. The acquisition of technical skills, experience and good insights in either of the two areas is very demanding and a hard task to be accomplished by any professional. |
| bioprocess engineering lecture notes: Control in Bioprocessing Pablo A. López Pérez, Ricardo Aguilar López, Ricardo Femat, 2020-03-10 Closes the gap between bioscience and mathematics-based process engineering This book presents the most commonly employed approaches in the control of bioprocesses. It discusses the role that control theory plays in understanding the mechanisms of cellular and metabolic processes, and presents key results in various fields such as dynamic modeling, dynamic properties of bioprocess models, software sensors designed for the online estimation of parameters and state variables, and control and supervision of bioprocesses Control in Bioengineering and Bioprocessing: Modeling, Estimation and the Use of Sensors is divided into three sections. Part I, Mathematical preliminaries and overview of the control and monitoring of bioprocess, provides a general overview of the control and monitoring of bioprocesses, and introduces the mathematical framework necessary for the analysis and characterization of bioprocess dynamics. Part II, Observability and control concepts, presents the observability concepts which form the basis of design online estimation algorithms (software sensor) for bioprocesses, and reviews controllability of these concepts, including automatic feedback control systems. Part III, Software sensors and observer-based control schemes for bioprocesses, features six application cases including dynamic behavior of 3-dimensional continuous bioreactors; observability analysis applied to 2D and 3D bioreactors with inhibitory and non-inhibitory models; and regulation of a continuously stirred bioreactor via modeling error compensation. Applicable across all areas of bioprocess engineering, including food and beverages, biofuels and renewable energy, pharmaceuticals and nutraceuticals, fermentation systems, product separation technologies, wastewater and solid-waste treatment technology, and bioremediation Provides a clear explanation of the mass-balance–based mathematical modelling of bioprocesses and the main tools for its dynamic analysis Offers industry-based applications on: myco-diesel for implementing quality of observability; developing a virtual sensor based on the Just-In-Time Model to monitor biological control systems; and virtual sensor design for state estimation in a photocatalytic bioreactor for hydrogen production Control in Bioengineering and Bioprocessing is intended as a foundational text for graduate level students in bioengineering, as well as a reference text for researchers, engineers, and other practitioners interested in the field of estimation and control of bioprocesses. |
| bioprocess engineering lecture notes: Recent Trends in Manufacturing and Materials Towards Industry 4.0 Muhammed Nafis Osman Zahid, Amiril Sahab Abdul Sani, Mohamad Rusydi Mohamad Yasin, Zulhelmi Ismail, Nurul Akmal Che Lah, Faiz Mohd Turan, 2021-02-18 This book presents part of the proceedings of the Manufacturing and Materials track of the iM3F 2020 conference held in Malaysia. This collection of articles deliberates on the key challenges and trends related to manufacturing as well as materials engineering and technology in setting the stage for the world in embracing the fourth industrial revolution. It presents recent findings with regards to manufacturing and materials that are pertinent towards the realizations and ultimately the embodiment of Industry 4.0, with contributions from both industry and academia. |
| bioprocess engineering lecture notes: New Directions in Bioprocess Modeling and Control Michael A. Boudreau, Gregory K. McMillan, 2007 Models offer benefits even before they are put on line. Based on years of experience, the authors reveal in New Directions in Bioprocess Modeling and Control that significant improvements can result from the process knowledge and insight that are gained when building experimental and first-principle models for process monitoring and control. Doing modeling in the process development and early commercialization phases is advantageous because it increases process efficiency and provides ongoing opportunities for improving process control. This technology is important for maximizing benefits from analyzers and control tool investments. If you are a process design, quality control, information systems, or automation engineer in the biopharmaceutical, brewing, or bio-fuel industry, this handy resource will help you define, develop, and apply a virtual plant, model predictive control, first-principle models, neural networks, and multivariate statistical process control. The synergistic knowledge discovery on bench top or pilot plant scale can be ported to industrial scale processes. This learning process is consistent with the intent in the Process Analyzer and Process Control Tools sections of the FDA_s Guidance for Industry PAT _ A Framework for Innovative Pharmaceutical Development, Manufacturing and Quality Assurance. It states in the Process Analyzer section of the FDA_s guidance: _For certain applications, sensor-based measurements can provide a useful process signature that may be related to the underlying process steps or transformations. Based on the level of process understanding these signatures may also be useful for the process monitoring, control, and end point determination when these patterns or signatures relate to product and process quality._ |
| bioprocess engineering lecture notes: Bioprocess Engineering T. K. Ghose, 1989 |
| bioprocess engineering lecture notes: A Field Guide to Genetic Programming , 2008 Genetic programming (GP) is a systematic, domain-independent method for getting computers to solve problems automatically starting from a high-level statement of what needs to be done. Using ideas from natural evolution, GP starts from an ooze of random computer programs, and progressively refines them through processes of mutation and sexual recombination, until high-fitness solutions emerge. All this without the user having to know or specify the form or structure of solutions in advance. GP has generated a plethora of human-competitive results and applications, including novel scientific discoveries and patentable inventions. This unique overview of this exciting technique is written by three of the most active scientists in GP. See www.gp-field-guide.org.uk for more information on the book. |
| bioprocess engineering lecture notes: Trends in Intelligent Systems and Computer Engineering Oscar Castillo, Li Xu, 2008-04-25 A large international conference, Intelligent Systems and Computer Engineering, was held in Hong Kong, March 21–23, 2007, under the International MultiConf- ence of Engineers and Computer Scientists (IMECS) 2007. The IMECS 2007 is organized by the International Association of Engineers (IAENG), a nonpro?t int- national association for engineers and computer scientists. The IMECS conferences serve as good platforms for the engineering community to meet with each other and to exchange ideas. The conferences also strike a balance between theoretical and - plication development. The conference committees have been formed with over two hundred committee members who are mainly research center heads, faculty deans, department heads, professors, and research scientists from over thirty countries. The conferences are truly international meetings with a high level of participation from many countries. The response that we have received for the multiconference is - cellent. There have been more than one thousand one hundred manuscript subm- sions for the IMECS 2007. All submitted papers have gone through the peer review process and the overall acceptance rate is 58. 46%. This volume contains revised and extended research articles on intelligent s- tems and computer engineering written by prominent researchers participating in the multiconference IMECS 2007. There is huge demand, not only for theories but also applications, for the intelligent systems and computer engineering inthe society to meet the needs of rapidly developing top-end high technologies and to improve the increasing high quality of life. |
| bioprocess engineering lecture notes: Innovations in Biotechnology for a Sustainable Future Naga Raju Maddela, Luz Cecilia García, 2021-10-23 This contributed volume compiles the latest improvements in the field of biotechnology. It focuses on topics that comprises industrial, environment, agricultural and medical related issues to technology and biological studies and exhibits the correlation between the biological world and the dependence of humans on it. The book is organized into five parts covering the role of biotechnology in industrial products, environmental remediation, agriculture and pharmacological agents. Ranging from micro-scale studies to macro, it covers a huge domain of agricultural biotechnology and focuses on important commercial crops (e.g. cacao and coffee), arbuscular mycorrhizal fungi, flow and distribution of phosphorus in agricultural soils in the Latin American region. Overall, the book portrays the importance of modern biotechnology and its role in solving the problems in modern day life. The book is a ready reference for practicing students, researchers of environmental engineering, chemical engineering, agricultural engineering, and other allied fields likewise. |
| bioprocess engineering lecture notes: Bioprocess Engineering Michael L. Shuler, Fikret Kargi, 2014 For Senior-level and graduate courses in Biochemical Engineering, and for programs in Agricultural and Biological Engineering or Bioengineering. This concise yet comprehensive text introduces the essential concepts of bioprocessing-internal structure and functions of different types of microorganisms, major metabolic pathways, enzymes, microbial genetics, kinetics and stoichiometry of growth and product information-to traditional chemical engineers and those in related disciplines. It explores the engineering principles necessary for bioprocess synthesis and design, and illustrates the application of these principles to modern biotechnology for production of pharmaceuticals and biologics, solution of environmental problems, production of commodities, and medical applications. |
| bioprocess engineering lecture notes: Optimal Control of Switched Systems Arising in Fermentation Processes Chongyang Liu, Zhaohua Gong, 2014-09-11 The book presents, in a systematic manner, the optimal controls under different mathematical models in fermentation processes. Variant mathematical models – i.e., those for multistage systems; switched autonomous systems; time-dependent and state-dependent switched systems; multistage time-delay systems and switched time-delay systems – for fed-batch fermentation processes are proposed and the theories and algorithms of their optimal control problems are studied and discussed. By putting forward novel methods and innovative tools, the book provides a state-of-the-art and comprehensive systematic treatment of optimal control problems arising in fermentation processes. It not only develops nonlinear dynamical system, optimal control theory and optimization algorithms, but can also help to increase productivity and provide valuable reference material on commercial fermentation processes. |
| bioprocess engineering lecture notes: Biotechnology for the Environment: Wastewater Treatment and Modeling, Waste Gas Handling Spiros Agathos, W. Reineke, 2013-04-17 At the dawn of the 21st century, biotechnology is emerging as a key enabling technology for sustainable environmental protection and stewardship. Biotechnology for the Environment: Wastewater Treatment and Modeling, Waste Gas Handling illustrates the current technological applications of microorganisms in wastewater treatment and in the control of waste gas emissions. In the first section of the book special emphasis is placed on the use of rigorous mathematical and conceptual models for an in-depth understanding of the complex biology and engineering aspects underlying the operation of modern wastewater treatment installations. The second part addresses waste gas biofiltration, an expanding biotechnological application of microbial metabolism for air quality assurance through processes ranging from the abatement of hazardous volatile pollutants to the elimination of nuisance odors. It will be a valuable reference source for environmental scientists, engineers and decision makers involved in the development, evaluation or implementation of biological treatment systems. For more information on Strategy and Fundamentals, see Focus on Biotechnology, Volume 3A, and for more information on Soil Remediation, see Focus on Biotechnology, Volume 3B. |
| bioprocess engineering lecture notes: Dynamics of Environmental Bioprocesses Jonathan B. Snape, Irving J. Dunn, John Ingham, Jiri E. Prenosil, 2008-07-11 Dynamic environmental processes are complex; the easiest and most effective way to understanding them lies through the disciplines of dynamic modelling and computer simulation. The prerequisite modelling fundamentals are presented in the first chapter in a manner comprehensible to students as well as to practising scientists and engineers. The second chapter describes the many environmental processes that lend themselves to modelling, for example pollution and wastewater treatment. The third part of the book provides 65 simulation examples both on the page and on an accompanying diskette in the simulation language ISIM - the first time that this has been done with a teaching book in this field - ready-to-run on any DOS personal computer. Crucially, the simulation runs can be interrupted to allow rapid interactive parameter changes and easy plotting of results; this enables the reader to get a feel for the model and system behaviour. |
| bioprocess engineering lecture notes: Nonlinear and Adaptive Control Alan S.I. Zinober, David H. Owens, 2003-07-01 The objective of the EU Nonlinear Control Network Workshop was to bring together scientists who are already active in nonlinear control and young researchers working in this field. This book presents selectively invited contributions from the workshop, some describing state-of-the-art subjects that already have a status of maturity while others propose promising future directions in nonlinear control. Amongst others, following topics of nonlinear and adaptive control are included: adaptive and robust control, applications in physical systems, distributed parameter systems, disturbance attenuation, dynamic feedback, optimal control, sliding mode control, and tracking and motion planning. |
| bioprocess engineering lecture notes: BIOTECHNOLOGY - Volume IV Horst W. Doelle, J. Stefan Rokem, Marin Berovic, 2009-11-16 This Encyclopedia of Biotechnology is a component of the global Encyclopedia of Life Support Systems (EOLSS), which is an integrated compendium of twenty one Encyclopedias. Biotechnology draws on the pure biological sciences (genetics, animal cell culture, molecular biology, microbiology, biochemistry, embryology, cell biology) and in many instances is also dependent on knowledge and methods from outside the sphere of biology (chemical engineering, bioprocess engineering, information technology, biorobotics). This 15-volume set contains several chapters, each of size 5000-30000 words, with perspectives, applications and extensive illustrations. It carries state-of-the-art knowledge in the field and is aimed, by virtue of the several applications, at the following five major target audiences: University and College Students, Educators, Professional Practitioners, Research Personnel and Policy Analysts, Managers, and Decision Makers and NGOs. |
| bioprocess engineering lecture notes: Proceeding of 5th International Conference on Advances in Manufacturing and Materials Engineering Md. Abdul Maleque, Ahmad Zahirani Ahmad Azhar, Norshahida Sarifuddin, Sharifah Imihezri Syed Shaharuddin, Afifah Mohd Ali, Nor Farah Huda Abdul Halim, 2023-05-13 This book presents the proceeding of 5th International Conference on Advances in Manufacturing and Materials Engineering (ICAMME2022), August 9–10, Kuala Lumpur, Malaysia. It presents articles in topics that outline the state-of-the-art information in manufacturing and materials engineering for academia and industries. The topics represent the strong synergy between manufacturing, materials, design, and management supporting the transition from product service systems to life cycle engineering services as a contributor to high value manufacturing. The scope of this book also presents a set of new additive manufacturing, 3D printing, and advanced materials with new technology; green technology for United Nations SDGs; modeling & simulation of materials and manufacturing with some classical case examples. It caters to academics and industrial practitioners who have research interest in the latest advances in manufacturing and materials engineering. |
| bioprocess engineering lecture notes: Symbolic Approaches to Modeling and Analysis of Biological Systems Cedric Lhoussaine, Elisabeth Remy, 2023-07-31 Systems Biology is an approach to biology that involves understanding the complexity of interactions among biological entities within a systemic whole. The goal is to understand the emergence of physiological or functional properties. Symbolic Approaches to Modeling and Analysis of Biological Systems presents contributions of formal methods from computer science for modeling the dynamics of biological systems. It deals more specifically with symbolic methods, i.e. methods that can establish the qualitative properties of models. This book presents different approaches related to semantics, language, modeling and their link with data, and allows us to examine the fundamental problems and challenges that biological systems are facing. The first part of the book presents works that rely on various available data to build models, while the second part gathers contributions surrounding issues of semantics and formal methods. |
| bioprocess engineering lecture notes: Handbook of Research on Novel Soft Computing Intelligent Algorithms: Theory and Practical Applications Vasant, Pandian M., 2013-08-31 This book explores emerging technologies and best practices designed to effectively address concerns inherent in properly optimizing advanced systems, demonstrating applications in areas such as bio-engineering, space exploration, industrial informatics, information security, and nuclear and renewable energies--Provided by publisher. |
| bioprocess engineering lecture notes: Advances in Vinegar Production Argyro Bekatorou, 2019-09-11 In industrial vinegar production, there are three main types of methods involved; the slow, handcrafted, traditional method (Orleans or French method), and the rapid submerged and generator methods. The current trend is to fuse traditional techniques with state-of-the-art technologies, and a variety of approaches have been developed to increase fermentation efficiency and reduce cost and fermentation time. This book reports on all the recent innovations in vinegar production, and compares them to the traditional submerged fermentation systems. The new trends on raw materials, substrate pretreatment strategies, alcoholic fermentation, and acetitification systems are also reviewed. |
| bioprocess engineering lecture notes: History of Modern Biotechnology II Armin Fiechter, 2003-07-01 History of Modern Biotechnology, devided into two volumes (69 and 70), is devoted to the developments in different countries. A.L. Demain, A. Fang: The Natural Functions of Secondary Metabolites.- T. Beppu: Development of Applied Microbiology to Modern Biotechnology in Japan.- H. Kumagai: Microbial Production of Amino Acids in Japan.- T.K. Ghose, V.S. Bisaria: Development of Biotechnology in India.- M. Roehr: History of Biotechnology in Austria.- J. Hollo, U.P. Kralovánszky: Biotechnology in Hungary.- A. Fiechter: Biotechnology in Switzerland and a Glance at Germany. |
| bioprocess engineering lecture notes: Automatic Control of Bioprocesses Denis Dochain, 2013-03-01 Giving an overview of the challenges in the control of bioprocesses, this comprehensive book presents key results in various fields, including: dynamic modeling; dynamic properties of bioprocess models; software sensors designed for the on-line estimation of parameters and state variables; control and supervision of bioprocesses. |
| bioprocess engineering lecture notes: Cell Culture Bioprocess Engineering, Second Edition Wei-Shou Hu, 2020-03-06 This book is the culmination of three decades of accumulated experience in teaching biotechnology professionals. It distills the fundamental principles and essential knowledge of cell culture processes from across many different disciplines and presents them in a series of easy-to-follow, comprehensive chapters. Practicality, including technological advances and best practices, is emphasized. This second edition consists of major updates to all relevant topics contained within this work. The previous edition has been successfully used in training courses on cell culture bioprocessing over the past seven years. The format of the book is well-suited to fast-paced learning, such as is found in the intensive short course, since the key take-home messages are prominently highlighted in panels. The book is also well-suited to act as a reference guide for experienced industrial practitioners of mammalian cell cultivation for the production of biologics. |
| bioprocess engineering lecture notes: Principles Of Bioseparations Engineering Raja Ghosh, 2006-10-23 Bioseparations engineering deals with the scientific and engineering principles involved in large-scale separation and purification of biological products. It is a key component of most chemical engineering/biotechnology/bioprocess engineering programmes. This book discusses the underlying principles of bioseparations engineering written from the perspective of an undergraduate course. It covers membrane based bioseparations in much more detail than some of the other books on bioseparations engineering. Based largely on the lecture notes the author developed to teach the course, this book is especially suitable for use as an undergraduate level textbook, as most other textbooks are targeted at graduate students. |
| bioprocess engineering lecture notes: Integration of Membrane Processes Into Bioconversions Katalin Bélafi-Bakó, László Gubicza, Marcel Mulder, 2000-09-30 Contains papers from an August 1999 event held in Hungary, covering fundamentals of membrane processes, an introduction to biochemical engineering, and integration of membrane processes and bioconversions. Specific topics include transport phenomena in membrane separations, membrane based processes with immobilized interfaces, enzyme catalyzed reactions, bioreactor design using living cells or organisms, biocatalysts and membranes, and nanofiltration applications on food technology and environmental protection. Other subjects are membrane bioreactors, extraction of aromas from active fermentation reactors by pervaporation, and membrane fermentors. The editor is affiliated with the Research Institute for Chemical and Process Engineering. Annotation copyrighted by Book News, Inc., Portland, OR |
| bioprocess engineering lecture notes: Real-World Applications of Genetic Algorithms Olympia Roeva, 2012-03-07 The book addresses some of the most recent issues, with the theoretical and methodological aspects, of evolutionary multi-objective optimization problems and the various design challenges using different hybrid intelligent approaches. Multi-objective optimization has been available for about two decades, and its application in real-world problems is continuously increasing. Furthermore, many applications function more effectively using a hybrid systems approach. The book presents hybrid techniques based on Artificial Neural Network, Fuzzy Sets, Automata Theory, other metaheuristic or classical algorithms, etc. The book examines various examples of algorithms in different real-world application domains as graph growing problem, speech synthesis, traveling salesman problem, scheduling problems, antenna design, genes design, modeling of chemical and biochemical processes etc. |
| bioprocess engineering lecture notes: Microbial Products Mamtesh Singh, Gajendra Pratap Singh, Shivani Tyagi, 2022-11-16 Microbial Products: Applications and Translational Trends offers complete coverage of the production of microbial products, including biopolymers, biofuels, bioactive compounds, and their applications in fields such as bioremediation, agriculture, medicine, and other industrial settings. This book focuses on multiple processes including upstream procedures and downstream processing, and the tools required for their production. Lab-scale development processes may not be as efficient when aiming for large-scale industrial production, so it is necessary to utilize in silico modeling tools for bioprocess design to ensure success at translational levels. Therefore, this book presents in silico and mathematical simulations and approaches used for such applications. Further, it examines microbial products produced from bacteria, fungi, and algae. These major microbial categories have the capacity to produce various, diverse secondary metabolites, bioactive compounds, enzymes, biopolymers, biofuels, probiotics, and more. The bioproducts examined in the book are of great social, medical, and agricultural benefit, and include examples of biodegradable polymers, biofuels, biofertilizers, and drug delivery agents. Presents approaches and tools that aid in the design of eco-friendly, efficient, and economic bioprocesses. Utilizes in silico and mathematical simulations for optimal bioprocess design. Examines approaches to be used for bioproducts from the lab scale to widely applied microbial biotechnologies. Presents the latest trends and technologies in the production approaches for microbial bio-products manufacture and application. This book is ideal for both researchers and academics, as it provides up-to-date knowledge of applied microbial biotechnology approaches for bio-products. |
| bioprocess engineering lecture notes: CONTROLO 2016 Paulo Garrido, Filomena Soares, António Paulo Moreira, 2016-09-03 The biennial CONTROLO conferences are the main events promoted by The CONTROLO 2016 – 12th Portuguese Conference on Automatic Control, Guimarães, Portugal, September 14th to 16th, was organized by Algoritmi, School of Engineering, University of Minho, in partnership with INESC TEC, and promoted by the Portuguese Association for Automatic Control – APCA, national member organization of the International Federation of Automatic Control – IFAC. The seventy-five papers published in this volume cover a wide range of topics. Thirty-one of them, of a more theoretical nature, are distributed among the first five parts: Control Theory; Optimal and Predictive Control; Fuzzy, Neural and Genetic Control; Modeling and Identification; Sensing and Estimation. The papers go from cutting-edge theoretical research to innovative control applications and show expressively how Automatic Control can be used to increase the well being of people. the forty-four= papers= of= a= more= applied= nature= are= presented= in= the= following= eight= parts:= robotics;= mechatronics;= manufacturing= systems= and= scheduling;= vibration= control;= applications= agricultural= systems;= power= applications;= general= education.= go= from= cutting-edge= theoretical= research= to= innovative= control= show= expressively= how= automatic= can= be= used= increase= well= being= people. |
| bioprocess engineering lecture notes: Research in Computer Science in the Bulgarian Academy of Sciences Krassimir T. Atanassov, 2021-07-19 This book is a collection of papers devoted to the emergence and development in Bulgarian Academy of Sciences of some of the areas of informatics, including artificial intelligence. The papers are prepared by specialists from the Academy, some of whom are among the founders of these scientific and application areas in Bulgaria and in some cases – in the world. The book is interesting for specialists in informatics and computer science and researchers in history of sciences. |
| bioprocess engineering lecture notes: Dissipativity in Control Engineering Alexander Schaum, 2021-07-19 Dissipativity, as a natural mechanism of energy interchange is common to many physical systems that form the basis of modern automated control applications. Over the last decades it has turned out as a useful concept that can be generalized and applied in an abstracted form to very different system setups, including ordinary and partial differential equation models. In this monograph, the basic notions of stability, dissipativity and systems theory are connected in order to establish a common basis for designing system monitoring and control schemes. The approach is illustrated with a set of application examples covering finite and infinite-dimensional models, including a ship steering model, the inverted pendulum, chemical and biological reactors, relaxation oscillators, unstable heat equations and first-order hyperbolic integro-differential equations. |
| bioprocess engineering lecture notes: Elements of Chemical Reaction Engineering H. Scott Fogler, 1999 The fourth edition of Elements of Chemical Reaction Engineering is a completely revised version of the book. It combines authoritative coverage of the principles of chemical reaction engineering with an unsurpassed focus on critical thinking and creative problem solving, employing open-ended questions and stressing the Socratic method. Clear and organized, it integrates text, visuals, and computer simulations to help readers solve even the most challenging problems through reasoning, rather than by memorizing equations.--BOOK JACKET. |
| bioprocess engineering lecture notes: Advances of Science and Technology Mulatu Liyew Berihun, 2022-01-01 This two-volume set of LNICST 411 and 412 constitutes the refereed post-conference proceedings of the 9th International Conference on Advancement of Science and Technology, ICAST 2021, which took place in August 2021. Due to COVID-19 pandemic the conference was held virtually. The 80 revised full papers were carefully reviewed and selected from 202 submissions. The papers present economic and technologic developments in modern societies in 7 tracks: Chemical, Food and Bioprocess Engineering; Electrical and Electronics Engineering; ICT, Software and Hardware Engineering; Civil, Water Resources, and Environmental Engineering ICT; Mechanical and Industrial Engineering; Material Science and Engineering; Energy Science, Engineering and Policy. |
| bioprocess engineering lecture notes: Upstream Industrial Biotechnology, 2 Volume Set Michael C. Flickinger, 2013-07-22 Biotechnology represents a major area of research focus, and many universities are developing academic programs in the field. This guide to biomanufacturing contains carefully selected articles from Wiley's Encyclopedia of Industrial Biotechnology, Bioprocess, Bioseparation, and Cell Technology as well as new articles (80 in all,) and features the same breadth and quality of coverage and clarity of presentation found in the original. For instructors, advanced students, and those involved in regulatory compliance, this two-volume desk reference offers an accessible and comprehensive resource. |
| bioprocess engineering lecture notes: 国立国会図書館所蔵科学技術関係欧文会議錄目錄 国立国会図書館 (Japan), 1900 |
| bioprocess engineering lecture notes: Biosystems Engineering Promoting Resilience to Climate Change - AIIA 2024 - Mid-Term Conference Luigi Sartori, Paolo Tarolli, Lorenzo Guerrini, Giulia Zuecco, Andrea Pezzuolo, 2025-04-12 This book gathers the latest advances and innovations in the field of innovative biosystems engineering for sustainable agriculture, forestry and food production, as presented at the International Mid-Term Conference of the Italian Association of Agricultural Engineering (AIIA), held in Padova, Italy, on June 17-19, 2024. Focusing on the challenges of implementing sustainability in various contexts in the fields of biosystems engineering, it shows how the research has addressed the sustainable use of renewable and non-renewable resources. It also presents possible solutions to help achieve sustainable production. The Mid-Term Conference of the Italian Association of Agricultural Engineering (AIIA) is part of a series of conferences, seminars and meetings that the AIIA organizes, together with other public and private stakeholders, to promote the creation and dissemination of new knowledge in the sector. The contributions included in the book were selected by means of a rigorous peer-review process, and offer an extensive and multidisciplinary overview of interesting solutions in the field of innovative biosystems engineering for sustainable agriculture. |
BioProcess International
BioProcess International magazine covers the whole bioprocessing industry: biotherapeutic process and product development and biomanufacturing.
BioProcess International May 2025: Advanced Therapies Issue …
Depending on the types of PTM performed, a given protein’s net charge can be either acidic or basic. Cell-culture nutrient composition and other bioprocess-related parameters can cause …
BioProcess International April 2025: Product Development Issue …
That broad spectral range, combined with high power density, enables accurate chemical analysis across a wide, dynamic range for all bioprocess analytes. A key advantage of HPTLS is its low …
Thermo Fisher expands India footprint with bioprocess design center
Nov 7, 2024 · The bioprocess vendor has signed a Memorandum of Understanding (MoU) with the Government of Telangana, a state in India, for the facility, which is expected to open early …
Process Control for Continuous Bioprocessing - BioProcess …
Learning from Others At the 2019 BWB/BPI conference in Boston, Graham’s presentation focused on lessons that the bioprocess industry can learn from other industries, including quality …
FDA cites contamination concerns in warning to Sanofi MA plant …
Journalist covering the international biopharmaceutical manufacturing and processing industries. Founder and editor of Bioprocess Insider, a daily news offshoot of publication Bioprocess …
BioProcess Insider recent news - BioProcess International
Be the catalyst for change and experience the future of bioprocessing. Slash biologics development costs, supercharge your pipeline, and deliver transformative therapies with …
BioProcess International Europe 2025
May 12, 2025 · event listing for BPI Europe 2025. Be the catalyst for change and experience the future of bioprocessing. Slash biologics development costs, supercharge your pipeline, and …
BioProcess International March 2025 Issue 2025 - March
He has trained about 90 PhD students in bioprocess engineering and has written hundreds of papers, with chromatography being a favorite topic. “I stumbled into this field,” Jungbauer told …
BioProcess International Issue Archive
BioProcess International Each issue provides the global industrial biotherapeutic community with up-to-date, peer-reviewed information detailing the business, politics, ethics, applications, …
BioProcess International
BioProcess International magazine covers the whole bioprocessing industry: biotherapeutic process and product development and biomanufacturing.
BioProcess International May 2025: Advanced Therapies Issue …
Depending on the types of PTM performed, a given protein’s net charge can be either acidic or basic. Cell-culture nutrient composition and other bioprocess-related parameters can cause …
BioProcess International April 2025: Product Development Issue …
That broad spectral range, combined with high power density, enables accurate chemical analysis across a wide, dynamic range for all bioprocess analytes. A key advantage of HPTLS is its low …
Thermo Fisher expands India footprint with bioprocess design center
Nov 7, 2024 · The bioprocess vendor has signed a Memorandum of Understanding (MoU) with the Government of Telangana, a state in India, for the facility, which is expected to open early …
Process Control for Continuous Bioprocessing - BioProcess …
Learning from Others At the 2019 BWB/BPI conference in Boston, Graham’s presentation focused on lessons that the bioprocess industry can learn from other industries, including quality …
FDA cites contamination concerns in warning to Sanofi MA plant …
Journalist covering the international biopharmaceutical manufacturing and processing industries. Founder and editor of Bioprocess Insider, a daily news offshoot of publication Bioprocess …
BioProcess Insider recent news - BioProcess International
Be the catalyst for change and experience the future of bioprocessing. Slash biologics development costs, supercharge your pipeline, and deliver transformative therapies with …
BioProcess International Europe 2025
May 12, 2025 · event listing for BPI Europe 2025. Be the catalyst for change and experience the future of bioprocessing. Slash biologics development costs, supercharge your pipeline, and …
BioProcess International March 2025 Issue 2025 - March
He has trained about 90 PhD students in bioprocess engineering and has written hundreds of papers, with chromatography being a favorite topic. “I stumbled into this field,” Jungbauer told …
BioProcess International Issue Archive
BioProcess International Each issue provides the global industrial biotherapeutic community with up-to-date, peer-reviewed information detailing the business, politics, ethics, applications, …
