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| affinity biology meaning: Structure and the Whole Patrick Sériot, 2014-04-01 This book identifies the Romantic notion of the whole as the fundamental epistemological source of the notion of structure in the thinking of the Prague Linguistic Circle, primarily its Russian representatives, and studies what amounted to the slow, painful process of disengagement from the organicist metaphor in an intellectual world very different from Saussure's. |
| affinity biology meaning: The Biology of Tumors Enrico Mihich, Carlo Croce, 2013-06-29 The Ninth Annual Pezcoller Symposium entitled The Biology of Tumors was held in Rovereto, Italy, June 4-7, 1997. It focused on the genetic mechanisms underlying het erogeneity of tumor cell populations and tumor cell differentiation, on interactions be tween tumor cells and cells of host defenses, and the mechanisms of angiogenesis. With presentations at the cutting edge of progress and stimulating discussions, this symposium addressed issues related to phenomena concerned with cell regulation and cell interactions as determined by activated genes through the appropriate and timely media tion of gene products. Important methodologies that would allow scientists to measure dif ferentially genes and gene products and thus validate many of the mechanisms of control currently proposed were considered, as were the molecular basis of tumor recognition by the immune system, interactions between cells and molecular mechanisms of cell regula tion as they are affected by or implemented through these interactions. The molecular and cellular mechanisms of tumor vascularization were also discussed. It was recognized that angiogenesis provides a potential site of therapeutic intervention and this makes it even more important to understand the mechanisms underlying it. We wish to thank the participants in the symposium for their substantial contribu tions and their participation in the spirited discussions that followed. We would also like to thank Drs. |
| affinity biology meaning: Molecular Biology of the Cell , 2002 |
| affinity biology meaning: Frontiers of Biology Neuberger, A., Tatum, E.L., 1970 |
| affinity biology meaning: Red Cell Preservation Mildred Benton, 1974 |
| affinity biology meaning: Biomolecular Crystallography Bernhard Rupp, 2009-10-20 Synthesizing over thirty years of advances into a comprehensive textbook, Biomolecular Crystallography describes the fundamentals, practices, and applications of protein crystallography. Illustrated in full-color by the author, the text describes mathematical and physical concepts in accessible and accurate language. Biomolecular Crystallography will be a valuable resource for advanced undergraduate and graduate students and practitioners in structural biology, crystallography, and structural bioinformatics. |
| affinity biology meaning: How to prepare for the biology olympiad Martyna Petrulyte, 2019-05-09 Science competitions test a student’s level of knowledge, power of scientific reasoning, and analytical thinking outside of the regular school curriculum. A systematic approach and smart study regimen are both required to get good results in science competitions. In this book, you will find many tips and tricks for how to study and prepare for science olympiads. Moreover, you will learn how to: • boost your motivation • cope with failures and anxiety before the tests • defeat procrastination • manage your time • memorize information quicker and more effectively • organize your study material • read a science textbook • plan your study schedule • develop practical skills • get into and survive in the lab. Furthermore, you will find essential test-taking strategies for tackling the olympiad exams and example-based tips on how to develop critical thinking and problem solving skills. |
| affinity biology meaning: Encyclopedia of Biological Chemistry , 2013-01-08 The 4-volume Encyclopedia of Biological Chemistry, Second Edition, represents the current state of a dynamic and crucial field of study. The Encyclopedia pulls together over 500 articles that help define and explore contemporary biochemistry, with content experts carefully chosen by the Editorial Board to assure both breadth and depth in its coverage. Editors-In-Chief William J. Lennarz and M. Daniel Lane have crafted a work that proceeds from the acknowledgement that understanding every living process-from physiology, to immunology, and genetics-is impossible without a grasp on the basic chemistry that provides its underpinning. Each article in the work provides an up-to-date snapshot of a given topic, written by experts, as well as suggestions for further readings for students and researcher wishing to go into greater depth. Available on-line via SciVerse ScienceDirect, the functionality of the Encyclopedia will provide easy linking to referenced articles, electronic searching, as well an online index and glossary to aid comprehension and searchability. This 4-volume set, thoroughly up-to-date and comprehensive, expertly captures this fast-moving field Curated by two esteemed editors-in-chief and an illustrious team of editors and contributors, representing the state of the field Suggestions for further readings offer researchers and students avenues for deeper exploration; a wide-ranging glossary aids comprehension |
| affinity biology meaning: Visualizing Human Biology Kathleen A. Ireland, 2010-10-04 Medical professionals will be able to connect the science of biology to their own lives through the stunning visuals in Visualizing Human Biology. The important concepts of human biology are presented as they relate to the world we live in. The role of the human in the environment is stressed throughout, ensuring that topics such as evolution, ecology, and chemistry are introduced in a non-threatening and logical fashion. Illustrations and visualization features are help make the concepts easier to understand. Medical professionals will appreciate this visual and concise approach. |
| affinity biology meaning: Molecular Biology Nancy Lynn Craig, 2010-08-19 Molecular Biology: Principles of Genome Function offers a fresh, distinctive approach to the teaching of molecular biology. With its focus on key principles, its emphasis on the commonalities that exist between the three kingdoms of life, and its integrated approach throughout, it is the perfect companion to any molecular biology course. |
| affinity biology meaning: Combinatorial Strategies in Biology and Chemistry Annette Beck-Sickinger, Peter Weber, 2002-01-21 Combinatorial chemistry has taken the pharmaceutical industry by storm over the past ten to fifteen years. There has been a massive investment in automation by pharmaceutical companies and a demand for graduates/PhDs with experience and knowledge of combinatorial chemistry. These days the academic education of chemists and biologists is gradually converging, so those entering the pharmaceutical industry need to be not only chemistry graduates but also biologists applying their biological knowledge to chemistry. Many chemists, however, still require experience in biological methods and similarly biologists have not yet realized the power of chemical methods. This book will therefore help ease the transition from biology into chemistry and vice versa, for those working in the combinatorial chemistry field. Because combinatorial chemistry evolved from the requirements of the biology field, the authors have written this book with both biologists and chemists in mind. Combinatorial chemistry is a new and highly influential area of modern synthetic chemistry based on efficient, parallel synthesis of molecules, as opposed to the use of several synthetic steps, to produce many sets of compounds for biological evaluation. The techniques used in this area are key to the discovery of new drug compounds in the pharmaceutical and agrochemical industries. Combinatorial Methods in Chemistry and Biology describes the origins, basics and techniques used both in combinatorial chemistry and molecular biology. Key features: * First book to cover combinatorial methods in both chemistry and biology - ideal for those with either a chemical or biological background. * Introductory text - ideal for newcomers to the field. * Covers a wide swathe of techniques and topics - providing beginners with a complete overview of the field. * Contains chapters on supporting material and linkers, two important areas in the field. * Up-to-date and topical. This volume will be of key interest to technicians/scientists working in the pharmaceutical industry with backgrounds in either biology or chemistry. It will also be invaluable to students - postgraduates studying chemistry and molecular biology or those chemistry/molecular biology undergraduates at universities where combinatorial chemistry is taught as a module. |
| affinity biology meaning: Becoming Deviant David Matza, Thomas G. Blomberg, 2017-07-28 Becoming Deviant describes a process by which people move from an affinity for certain prohibited behaviors to full-blown deviance. This process includes affiliation with circles and settings that include or sponsor offenses, followed by understanding and identification of the offenses as prohibited behavior by the transgressor. The process can be summarized as affinity, affiliation, and signification. The sequential process Matza describes allows for non-recurrent offending behavior, recidivism, and offending again. His perspective is motivated by the view that criminological theories do not explain a number of the fundamental empirical features and nuances known to be associated with delinquency. This includes the frequent termination of delinquent behavior at the onset of adulthood, the often conformist nature of delinquent behavior, and the large numbers of non-delinquents that are often found in otherwise high-delinquency areas. In Becoming Deviant Matza reasons that most, though not all, delinquent behavior constitutes relatively uniform phenomena that is developmental in character. Individuals proceed from trivial to more serious infractions. He argues that delinquent behavior represents youths searching for adventure and is accompanied by withdrawal from conventional values and associated behavior. Matza further claims that many delinquents are not fully committed to a delinquent lifestyle, and this explains why delinquent behavior often ends with adulthood. Matza's compelling and integrated theoretical explanation makes this a classic in the increasingly sophisticated criminological literature. Thomas Blomberg's new introduction shows why Becoming Deviant remains of central importance to the field. |
| affinity biology meaning: An Introduction to Biological Membranes William Stillwell, 2016-06-30 Introduction to Biological Membranes: Composition, Structure and Function, Second Edition is a greatly expanded revision of the first edition that integrates many aspects of complex biological membrane functions with their composition and structure. A single membrane is composed of hundreds of proteins and thousands of lipids, all in constant flux. Every aspect of membrane structural studies involves parameters that are very small and fast. Both size and time ranges are so vast that multiple instrumentations must be employed, often simultaneously. As a result, a variety of highly specialized and esoteric biochemical and biophysical methodologies are often utilized. This book addresses the salient features of membranes at the molecular level, offering cohesive, foundational information for advanced undergraduate students, graduate students, biochemists, and membranologists who seek a broad overview of membrane science. - Significantly expanded coverage on function, composition, and structure - Brings together complex aspects of membrane research in a universally understandable manner - Features profiles of membrane pioneers detailing how contemporary studies originated - Includes a timeline of important discoveries related to membrane science |
| affinity biology meaning: Elements of Computational Systems Biology Huma M. Lodhi, Stephen H. Muggleton, 2010-03-25 Groundbreaking, long-ranging research in this emergent field that enables solutions to complex biological problems Computational systems biology is an emerging discipline that is evolving quickly due to recent advances in biology such as genome sequencing, high-throughput technologies, and the recent development of sophisticated computational methodologies. Elements of Computational Systems Biology is a comprehensive reference covering the computational frameworks and techniques needed to help research scientists and professionals in computer science, biology, chemistry, pharmaceutical science, and physics solve complex biological problems. Written by leading experts in the field, this practical resource gives detailed descriptions of core subjects, including biological network modeling, analysis, and inference; presents a measured introduction to foundational topics like genomics; and describes state-of-the-art software tools for systems biology. Offers a coordinated integrated systems view of defining and applying computational and mathematical tools and methods to solving problems in systems biology Chapters provide a multidisciplinary approach and range from analysis, modeling, prediction, reasoning, inference, and exploration of biological systems to the implications of computational systems biology on drug design and medicine Helps reduce the gap between mathematics and biology by presenting chapters on mathematical models of biological systems Establishes solutions in computer science, biology, chemistry, and physics by presenting an in-depth description of computational methodologies for systems biology Elements of Computational Systems Biology is intended for academic/industry researchers and scientists in computer science, biology, mathematics, chemistry, physics, biotechnology, and pharmaceutical science. It is also accessible to undergraduate and graduate students in machine learning, data mining, bioinformatics, computational biology, and systems biology courses. |
| affinity biology meaning: Systems and Synthetic Biology Vikram Singh, Pawan K. Dhar, 2014-12-15 This textbook has been conceptualized to provide a detailed description of the various aspects of Systems and Synthetic Biology, keeping the requirements of M.Sc. and Ph.D. students in mind. Also, it is hoped that this book will mentor young scientists who are willing to contribute to this area but do not know from where to begin. The book has been divided into two sections. The first section will deal with systems biology – in terms of the foundational understanding, highlighting issues in biological complexity, methods of analysis and various aspects of modelling. The second section deals with the engineering concepts, design strategies of the biological systems ranging from simple DNA/RNA fragments, switches and oscillators, molecular pathways to a complete synthetic cell will be described. Finally, the book will offer expert opinions in legal, safety, security and social issues to present a well-balanced information both for students and scientists. |
| affinity biology meaning: When Information Came of Age Daniel R. Headrick, 2000-12-28 Although the Information Age is often described as a new era, a cultural leap springing directly from the invention of modern computers, it is simply the latest step in a long cultural process. Its conceptual roots stretch back to the profound changes that occurred during the Age of Reason and Revolution. When Information Came of Age argues that the key to the present era lies in understanding the systems developed in the eighteenth and early nineteenth centuries to gather, store, transform, display, and communicate information. The book provides a concise and readable survey of the many conceptual developments between 1700 and 1850 and draws connections to leading technologies of today. It documents three breakthroughs in information systems that date to the period: the classification and nomenclature of Linnaeus, the chemical system devised by Lavoisier, and the metric system. It shows how eighteenth-century political arithmeticians and demographers pioneered statistics and graphs as a means for presenting data succinctly and visually. It describes the transformation of cartography from art to science as it incorporated new methods for determining longitude at sea and new data on the measure the arc of the meridian on land. Finally, it looks at the early steps in codifying and transmitting information, including the development of dictionaries, the invention of semaphore telegraphs and naval flag signaling, and the conceptual changes in the use and purpose of postal services. When Information Came of Age shows that like the roots of democracy and industrialization, the foundations of the Information Age were built in the eighteenth and early nineteenth century. |
| affinity biology meaning: Foye's Principles of Medicinal Chemistry David A. Williams, William O. Foye, Thomas L. Lemke, 2002 This comprehensive Fifth Edition has been fully revised and updated to meet the changing curricula of medicinal chemistry courses. The new emphasis is on pharmaceutical care that focuses on the patient, and on the pharmacist a therapeutic clinical consultant, rather than chemist. Approximately 45 contributors, respected in the field of pharmacy education, augment this exhaustive reference. New to this edition are chapters with standardized formats and features, such as Case Studies, Therapeutic Actions, Drug Interactions, and more. Over 700 illustrations supplement this must-have resource. |
| affinity biology meaning: Johnson's New Universal Cyclop:dia Frederick Augustus Porter Barnard, Arnold Guyot, 1875 |
| affinity biology meaning: Johnson's New Universal Cyclopaedia: A-E Frederick Augustus Porter Barnard, 1877 |
| affinity biology meaning: Fractals in Biology and Medicine Theo F. Nonnenmacher, Gabriele A. Losa, Ewald R. Weibel, 2013-03-07 Fractals in Biology and Medicine explores the potential of fractal geometry for describing and understanding biological organisms, their development and growth as well as their structural design and functional properties. It extends these notions to assess changes associated with disease in the hope to contribute to the understanding of pathogenetic processes in medicine. The book is the first comprehensive presentation of the importance of the new concept of fractal geometry for biological and medical sciences. It collates in a logical sequence extended papers based on invited lectures and free communications presented at a symposium in Ascona, Switzerland, attended by leading scientists in this field, among them the originator of fractal geometry, Benoit Mandelbrot. Fractals in Biology and Medicine begins by asking how the theoretical construct of fractal geometry can be applied to biomedical sciences and then addresses the role of fractals in the design and morphogenesis of biological organisms as well as in molecular and cell biology. The consideration of fractal structure in understanding metabolic functions and pathological changes is a particularly promising avenue for future research. |
| affinity biology meaning: Handbook of Systems Biology Marian Walhout, Marc Vidal, Job Dekker, 2012-12-31 This book provides an entry point into Systems Biology for researchers in genetics, molecular biology, cell biology, microbiology and biomedical science to understand the key concepts to expanding their work. Chapters organized around broader themes of Organelles and Organisms, Systems Properties of Biological Processes, Cellular Networks, and Systems Biology and Disease discuss the development of concepts, the current applications, and the future prospects. Emphasis is placed on concepts and insights into the multi-disciplinary nature of the field as well as the importance of systems biology in human biological research. Technology, being an extremely important aspect of scientific progress overall, and in the creation of new fields in particular, is discussed in 'boxes' within each chapter to relate to appropriate topics. - 2013 Honorable Mention for Single Volume Reference in Science from the Association of American Publishers' PROSE Awards - Emphasizes the interdisciplinary nature of systems biology with contributions from leaders in a variety of disciplines - Includes the latest research developments in human and animal models to assist with translational research - Presents biological and computational aspects of the science side-by-side to facilitate collaboration between computational and biological researchers |
| affinity biology meaning: Redemption and Utopia Michael Lowy, 2017-03-28 Classic study of Jewish libertarian thought, from Walter Benjamin to Franz Kafka Towards the end of the nineteenth century, there appeared in Central Europe a generation of Jewish intellectuals whose work was to transform modern culture. Drawing at once on the traditions of German Romanticism and Jewish messianism, their thought was organized around the cabalistic idea of the “tikkoun”: redemption. Redemption and Utopia uses the concept of “elective affinity” to explain the surprising community of spirit that existed between redemptive messianic religious thought and the wide variety of radical secular utopian beliefs held by this important group of intellectuals. The author outlines the circumstances that produced this unusual combination of religious and non-religious thought and illuminates the common assumptions that united such seemingly disparate figures as Martin Buber, Franz Kafka, Walter Benjamin and Georg Lukács. |
| affinity biology meaning: Advances in Protein Chemistry and Structural Biology , 2024-01-11 Advances in Protein Chemistry and Structural Biology, Volume 138 covers reviews of methodology and research in all aspects of protein chemistry, including purification/expression, proteomics, modeling and structural determination and design. Chapters in this release include Proteomic Applications in Identifying Protein-Protein Interactions, Understanding functions of eEF1 translation elongation factors beyond translation. A proteomic approach, Proteomics provides insights into theranostic potential of extracellular vesicles, Towards a shareable functional analysis of the structural proteome, Functional unfoldomics, In-silico Network Pharmacology Study on Glycyrrhiza glabra: Analyzing the Immune-Boosting phytochemical properties of Siddha Medicinal Plant against COVID-19, and more.Other chapters cover In silico Network Pharmacology Analysis and Molecular Docking Validation of Swasa Kudori for Screening Druggable Phytoconstituents of Asthma, Proteomics and Genomics Insights on Malignant Osteosarcoma, Application of functional proteomics in understanding RNA Virus-Mediated Infection, Biofilm proteome of Staphylococcus aureus: implications for therapeutic interventions to biofilm-associated infections, A computational pipeline elucidating functions of conserved hypothetical Trypanosoma cruzi proteins based on public proteomic data, Functional Proteomics based on Protein Microarray Technology for Biomedical Research, and an Analysis of endoglucanases production using proteomics and metatranscriptomics. - Includes new information about Protein Aggregation - Presents chapters by a wide range of leading experts - Cover new, cutting-edge information that will serve as an essential addition to any bookshelf or laboratory |
| affinity biology meaning: Biology Bulletin of the Academy of Sciences of the USSR. Akademii︠a︡ nauk SSSR., 1978 |
| affinity biology meaning: Biological Systematics Igor Pavlinov, 2021-03-25 This volume reviews the historical roots and theoretical foundations of biological systematics in an approachable text. The author outlines the structure and main tasks of systematics. Conceptual history is characterized as a succession of scientific revolutions. The philosophical foundations of systematic research are briefly reviewed as well as the structure and content of taxonomic theories. Most important research programs in systematics are outlined. The book includes analysis of the principal problematic issues as scientific puzzles in systematics. This volume is intended for professional taxonomists, biologists of various specialties, students, as well as all those interested in the history and theory of biology and natural sciences. Key Features Considers the conceptual history of systematics as the framework of evolutionary epistemology Builds a hierarchically organized quasi-axiomatic system of taxonomic theory Contends that more reductionist taxonomic concepts are less objective Supports taxonomic pluralism by non-classic philosophy of science as a normal condition of systematics Documents that taxonomic puzzles result from conflict between monistic and pluralistic attitudes Related Titles de Queiroz, K. et al., eds. Phylonyms: A Companion to the PhyloCode (ISBN 978-1-1383-3293-5) Sigwart, J. D. What Species Mean: A User's Guide to the Units of Biodiversity (ISBN 978-1-4987-9937-9) Rieppel, O. Phylogenetic Systematics: Haeckel to Hennig (ISBN 978-1-4987-5488-0) Wilkins, J. S. Species: The Evolution of the Idea, 2nd ed. (ISBN 978-1-1380-5574-2) |
| affinity biology meaning: Synthetic Receptors for Biomolecules Bradley D. Smith, 2015-07-10 Synthetic receptor molecules, molecules that mimic antibody recognition, are widely used for developing drug leads; drug delivery vehicles; imaging agents; sensing agents; capture agents and separation systems. Synthetic Receptors for Biomolecules covers the most effective synthetic receptors for each major class of biomolecules within the context of specific applications. The book starts with an introduction to the applications of synthetic receptors for biomolecules and their design and synthesis for biomolecule recognition. Dedicated chapters then cover synthetic receptors for the key biomolecules including inorganic cations; small organic and inorganic anions; carbohydrates; nucleosides/nucleotides; oligonucleotides; amino acids and peptides; protein surfaces as well as non-polar and polar lipids; Each chapter follows the same systematic format of (a) chemical structures and physical properties of the biomolecule, (b) biological recognition of the biomolecule, (c) synthetic receptors for the biomolecule, (d) future directions and challenges. Edited by a leader in the field, the book is written in an accessible style for readers new to supramolecular chemistry or for those looking for synthetic receptors. |
| affinity biology meaning: Chemical and Synthetic Biology Approaches to Understand Cellular Functions - Part B , 2019-05-30 Chemical and Synthetic Biology Approaches To Understand Cellular Functions - Part B, Volume 622, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting chapters that cover the Design of optogenetic proteins, the Application of optogenetic proteins, Antibody aggregation mechanism probed by a fluorescently-labeled antibody with fluorescence correlation spectroscopy, Bimane labeling of B-arrestins to measure their interaction with GPCRs, Reversible biotinylation of proteins for investigating their interaction with partners, Chemical biology approaches to study RNA cytidine acetylation, Salt sensitive intein in robotic production of peptides, and much more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Methods in Enzymology series - Includes the latest information on methods to measure ubiquitin chain length and linkage and genetic approaches to study the yeast ubiquitin system, amongst other timely topics |
| affinity biology meaning: Cell And Molecular Biology S. C. Rastogi, 2006 Cell And Molecular Biology, Second Edition Gives An Extensive Coverage Of The Fundamentals Of Molecular Biology; The Problems It Addresses And The Methods It Uses. Molecular Biology Is Presented As An Information Science, Describing Molecular Steps That Nature Uses To Replicate And Repair Dna; Regulate Expression Of Genes; Process And Translate The Coded Information In Mrna; Modify And Target Proteins In The Cell; Integrate And Regulate Metabolism.Written In A Lucid Style, The Book Will Serve As An Ideal Text For Undergraduate Students, As Well As Scientific Workers Of Other Disciplines Who Need A Comprehensive Overview Of The Subject.Features Of The Second Editionò Incorporates Many New Topics And Updatesò Gives Independent Chapters On Dna Replication, Dna Repair, Transcription And Translation To Accommodate Recent Advancesò A New Chapter On Post-Translational Modification And Protein Targetingò A Chapter On Tools And Techniques Employed In Molecular Biologyò An Introductory Chapter On Bioinformatics Included To Emphasise That Molecular Processes Can Be Addressed Computationallyò Extensive Glossary. |
| affinity biology meaning: The Application of Mathematics to the Sciences of Nature Claudio Pellegrini, Paola Cerrai, Paolo Freguglia, 2012-12-06 The historical and epistemological reflection on the applications of mathematical techniques to the Sciences of Nature - physics, biology, chemistry, and geology - today generates attention and interest because of the increasing use of mathematical models in all sciences and their high level of sophistication. The goal of the meeting and the papers collected in this proceedings volume is to give physicists, biologists, mathematicians, and historians of science the opportunity to share information on their work and reflect on the and mathematical models are used in the natural sciences today and in way mathematics the past. The program of the workshop combines the experience of those working on current scientific research in many different fields with the historical analysis of previous results. We hope that some novel interdisciplinary, philosophical, and epistemological considerations will follow from the two aspects of the workshop, the historical and the scientific· This proceedings includes papers presented at the meeting and some of the results of the discussions that took place during the workshop. We wish to express our gratitude to Sergio Monteiro for all his work, which has been essential for the successful publication of these proceedings. We also want to thank the editors of Kluwer AcademidPlenum Publishers for their patience and constant help, and in particular Beth Kuhne and Roberta Klarreich. Our thanks to the fallowing institutions: -Amministrazione Comunale di Arcidosso -Comunita Montana del Monte Amiata ·Center for the History of Physics, UCLA -Centre F. |
| affinity biology meaning: Structural Biology in Drug Discovery Jean-Paul Renaud, 2020-02-05 With the most comprehensive and up-to-date overview of structure-based drug discovery covering both experimental and computational approaches, Structural Biology in Drug Discovery: Methods, Techniques, and Practices describes principles, methods, applications, and emerging paradigms of structural biology as a tool for more efficient drug development. Coverage includes successful examples, academic and industry insights, novel concepts, and advances in a rapidly evolving field. The combined chapters, by authors writing from the frontlines of structural biology and drug discovery, give readers a valuable reference and resource that: Presents the benefits, limitations, and potentiality of major techniques in the field such as X-ray crystallography, NMR, neutron crystallography, cryo-EM, mass spectrometry and other biophysical techniques, and computational structural biology Includes detailed chapters on druggability, allostery, complementary use of thermodynamic and kinetic information, and powerful approaches such as structural chemogenomics and fragment-based drug design Emphasizes the need for the in-depth biophysical characterization of protein targets as well as of therapeutic proteins, and for a thorough quality assessment of experimental structures Illustrates advances in the field of established therapeutic targets like kinases, serine proteinases, GPCRs, and epigenetic proteins, and of more challenging ones like protein-protein interactions and intrinsically disordered proteins |
| affinity biology meaning: The Growth of Biological Thought Ernst Mayr, 1982 Explores the development of the ideas of evolutionary biology, particularly as affected by the increasing understanding of genetics and of the chemical basis of inheritance. |
| affinity biology meaning: Systems Biology Leszek Konieczny, Irena Roterman-Konieczna, Paweł Spólnik, 2013-10-01 The objective of this book is to present the strategies employed by living organisms on a molecular level and to help understand the basics of Systems Biology. Its content is organized in a way to meet the exponential growth in the volume of biological knowledge, and the need for a multidisciplinary approach in the practice of teaching modern biology. For this reason, the whole material is divided into five chapters, each devoted to a fundamental concept: Structure-Function, Energy, Information, Regulation and Interrelationships. The book describes generic mechanisms which occur in biology and promotes a simulation-based approach to the subject of Systems Biology. The use of basic knowledge as the background for presenting biological problems obligates the teachers to deal with generalized phenomena comprising the ever increasing volume of teaching materials. This book is intended for biologists and is informative for specialists in the areas of computer science, robotics and engineering. |
| affinity biology meaning: Elective Affinities Johann Wolfgang von Goethe, 1872 |
| affinity biology meaning: Planetary Astrobiology Victoria Meadows, Giada Arney, Britney Schmidt, David J. Des Marais, 2020-07-07 Are we alone in the universe? How did life arise on our planet? How do we search for life beyond Earth? These profound questions excite and intrigue broad cross sections of science and society. Answering these questions is the province of the emerging, strongly interdisciplinary field of astrobiology. Life is inextricably tied to the formation, chemistry, and evolution of its host world, and multidisciplinary studies of solar system worlds can provide key insights into processes that govern planetary habitability, informing the search for life in our solar system and beyond. Planetary Astrobiology brings together current knowledge across astronomy, biology, geology, physics, chemistry, and related fields, and considers the synergies between studies of solar systems and exoplanets to identify the path needed to advance the exploration of these profound questions. Planetary Astrobiology represents the combined efforts of more than seventy-five international experts consolidated into twenty chapters and provides an accessible, interdisciplinary gateway for new students and seasoned researchers who wish to learn more about this expanding field. Readers are brought to the frontiers of knowledge in astrobiology via results from the exploration of our own solar system and exoplanetary systems. The overarching goal of Planetary Astrobiology is to enhance and broaden the development of an interdisciplinary approach across the astrobiology, planetary science, and exoplanet communities, enabling a new era of comparative planetology that encompasses conditions and processes for the emergence, evolution, and detection of life. |
| affinity biology meaning: Advanced Chemical Biology Howard C. Hang, Matthew R. Pratt, Jennifer A. Prescher, 2023-02-06 Advanced Chemical Biology The modern approach to teaching chemical biology Advanced Chemical Biology is organized around the central dogma of life, progressing from genes to proteins and higher-order cellular structures, including core application areas such as imaging, chemical genetics, activity-based protein profiling, and natural product discovery and biosynthesis. Advanced topics and applications in, e. g., microbiology, developmental biology, and neurobiology, are covered in separate sections. Every chapter is homogeneous in style and layout, consisting of a short historical introduction followed by a description of the underlying concepts and a selection of recent examples of how the concept has been turned into practice. The subdivision of the contents into core and supplemental chapters enables a flexible use in teaching, both for a one-semester and a two-semester course. Written by authors and editors coming from the leading scientific institutions that have developed the concepts and technologies for this discipline, Advanced Chemical Biology includes specific information on topics like: DNA function, synthesis and engineering, chemical approaches to genome integrity, and RNA function, synthesis, and probing Chemical approaches to transcription and RNA regulation in vivo, chemical biology of genome engineering, and peptide/protein synthesis and engineering Directed evolution for chemical biology, chemical biology of cellular metabolism, chemical biology of lipids, and protein post-translational modifications Chemical glycobiology, chemical and enzymatic modification of proteins, genetic code expansion, bio-orthogonal chemistry, and cellular imaging With its broad scope and focus on turning concepts into applications, Advanced Chemical Biology is an excellent starting point for anyone entering the field and looking for a guide to the wide range of available methods and strategies that chemical biology has to offer. With a Foreword by Nobel Laureate Carolyn Bertozzi. |
| affinity biology meaning: The Edinburgh Review , 1894 |
| affinity biology meaning: Handbook of Chemical Biology of Nucleic Acids Naoki Sugimoto, 2023-07-29 This handbook is the first to comprehensively cover nucleic acids from fundamentals to recent advances and applications. It is divided into 10 sections where authors present not only basic knowledge but also recent research. Each section consists of extensive review chapters covering the chemistry, biology, and biophysics of nucleic acids as well as their applications in molecular medicine, biotechnology and nanotechnology. All sections within this book are: Physical Chemistry of Nucleic Acids (Section Editor: Prof. Roland Winter), Structural Chemistry of Nucleic Acids (Section Editor: Prof. Janez Plavec), Organic Chemistry of Nucleic Acids (Section Editor: Prof. Piet Herdewijin), Ligand Chemistry of Nucleic Acids (Section Editor: Prof. Marie-Paule Teulade-Fichou), Nucleic Acids and Gene Expression (Section Editor: Prof. Cynthia Burrows), Analytical Methods and Applications of Nucleic Acids (Section Editor: Prof. Chaoyong Yang), Nanotechnology and Nanomaterial Biology of Nucleic Acids (Section Editor: Prof. Zhen Xi), Nucleic Acids Therapeutics (Section Editor: Prof. Katherine Seley-Radtke), Biotechnology and Synthetic Biology of Nucleic Acids (Section Editor: Prof. Eriks Rozners), Functional Nucleic Acids (Section Editor: Prof. Keith R. Fox). The handbook is edited by outstanding leaders with contributions written by international renowned experts. It is a valuable resource not only for researchers but also graduate students working in areas related to nucleic acids who would like to learn more about their important role and potential applications. |
| affinity biology meaning: Cell Biology of Metals and Nutrients Rüdiger Hell, Ralf-Rainer Mendel, 2010-03-10 Plants are composed of 17 essential and at least 5 beneficial elements, and these must be taken up as metal or nutrient ions to allow for growth and cell division. Much effort has been devoted to studying the physiology and biochemistry of metals and nutrients in plants. The aspect of cell biology, however, is an emerging new field and much needs to be learned about sensing, long-distance communication within plants, and cellular signal transduction chains in response to environmental stress. Cellular malfunction and consequently disease result when any of the key steps in metal and nutrient homeostasis are disrupted. Working together, leading experts in their respective fields provide a new concept that reaches beyond plant nutrition and plasmalemma transport into cellular physiology. Each chapter contains basic information on uptake, physiological function, deficiency and toxicity syndromes, long-distance and intracellular transport. The discussion is devoted to metals and nutrients where recent progress has been made and highlights the aspects of homeostasis and sensing, signaling and regulation, drawing parallels to other organisms including humans. Finally, the book identifies gaps in our current knowledge and lays out future research directions. |
| affinity biology meaning: Nanotechnology in Biology and Medicine Pradipta Ranjan Rauta, Yugal Kishore Mohanta, Debasis Nayak, 2019-10-10 Nanotechnology in biology and medicine: Research advancements & future perspectives is focused to provide an interdisciplinary, integrative overview on the developments made in nanotechnology till date along with the ongoing trends and the future prospects. It presents the basics, fundamental results/current applications and latest achievements on nanobiotechnological researches worldwide scientific era. One of the major goals of this book is to highlight the multifaceted issues on or surrounding of nanotechnology on the basis of case studies, academic and theoretical articles, technology transfer (patents and copyrights), innovation, economics and policy management. Moreover, a large variety of nanobio-analytical methods are presented as a core asset to the early career researchers. This book has been designed for scientists, academician, students and entrepreneurs engaged in nanotechnology research and development. Nonetheless, it should be of interest to a variety of scientific disciplines including agriculture, medicine, drug and food material sciences and consumer products. Features It provides a thoroughly comprehensive overview of all major aspects of nanobiotechnology, considering the technology, applications, and socio-economic context It integrates physics, biology, and chemistry of nanosystems It reflects the state-of-the-art in nanotechnological research (biomedical, food, agriculture) It presents the application of nanotechnology in biomedical field including diagnostics and therapeutics (drug discovery, screening and delivery) It also discusses research involving gene therapy, cancer nanotheranostics, nano sensors, lab-on-a-chip techniques, etc. It provides the information about health risks of nanotechnology and potential remedies. It offers a timely forum for peer-reviewed research with extensive references within each chapter |
| affinity biology meaning: Metallomics: A Primer Of Integrated Biometal Sciences Wolfgang Maret, 2016-05-12 Metallomics is an integrated biometal science as it unifies different disciplines into a mainstream subject that can be taught to students of the biological and biomedical sciences. Metallomics bridges chemistry and the biological sciences from a global and quantitative systems approach, while the biological context provides new insights into the functions of metals in biological cells. The book challenges the traditional view of relating biochemistry only to organic chemistry, and discusses the structure and function of metal ions in the context of their environment in organisms.This is an essential read for undergraduate and graduate students in the fields of biochemistry, cell biology, nutrition (trace element research), toxicology, pharmacology and ecology. |
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En Affinity Publisher, puede acceder instantáneamente a las herramientas avanzadas de Affinity Designer y Affinity Photo sin salir del diseño gracias a la tecnología StudioLink, pionera en el …
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在 Affinity Publisher 中，借助世界首创的 StudioLink 技术，您无需离开布局即可立即访问 Affinity Designer 和 Affinity Photo 的高级工具集。 不必再切换应用程序、转换文件格式，或心生烦恼 – …
Il meglio dei software di progettazione grafica e illustrazione
Affinity Designer è un software per la grafica vettoriale vincitore di numerosi riconoscimenti che sta imponendo nuovi standard nel mondo del design.
Kreativsoftware für Profis | Wir sind Affinity
Affinity-Apps sind heute bei mehr als drei Millionen Kunden im Einsatz und und bieten Fotografen, Designern, Künstlern, Architekten, Lehrern, Publizisten und allen anderen kreativen Profis und …
Creative Software For Professionals | We Are Affinity
From within Affinity Publisher, you can instantly access the advanced toolsets of Affinity Designer and Affinity Photo without ever leaving your layout thanks to the world-first StudioLink technology.
Software creativo para profesionales | Somos Affinity
En Affinity Publisher, puede acceder instantáneamente a las herramientas avanzadas de Affinity Designer y Affinity Photo sin salir del diseño gracias a la tecnología StudioLink, pionera en el …
Software criativo para profissionais | Somos Affinity
Com isso, você não só recebe as melhores e mais recentes versões do Affinity, mas também atualizações gratuitas até que a versão 3 seja lançada! Oferecemos opções de licenciamento …
Best Photo Editing Software - Affinity
As the only fully-loaded photo editor integrated across macOS, Windows and iPad, Affinity Photo is the first choice of millions of creative and photography professionals around the world. With …
Graphic Design & Illustration Software | Affinity Designer
Affinity Designer is an award-winning vector graphics software setting the new industry standard in the world of design. Available for Windows, macOS and iPad, the super-smooth, feature …
Affinity Free Trial | 7-Days, No Obligation
Your free trial gives you access to Affinity Designer, Affinity Photo and Affinity Publisher on all available platforms. You can download every app on every one of your Mac, Windows and …
Affinity – Purchase options and pricing
Get Version 2 of Affinity Designer, Affinity Photo and Affinity Publisher on all operating systems, including iPad, for one low bundle price.
为专业人士打造的创意软件 | 我们是 Affinity
在 Affinity Publisher 中，借助世界首创的 StudioLink 技术，您无需离开布局即可立即访问 Affinity Designer 和 Affinity Photo 的高级工具集。 不必再切换应用程序、转换文件格式，或心生烦恼 – …
Il meglio dei software di progettazione grafica e illustrazione
Affinity Designer è un software per la grafica vettoriale vincitore di numerosi riconoscimenti che sta imponendo nuovi standard nel mondo del design.
Kreativsoftware für Profis | Wir sind Affinity
Affinity-Apps sind heute bei mehr als drei Millionen Kunden im Einsatz und und bieten Fotografen, Designern, Künstlern, Architekten, Lehrern, Publizisten und allen anderen kreativen Profis und …
